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GSE58827: Dynamics of the Mouse Liver

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Results for Rfx2_Rfx7

Z-value: 0.90

Motif logo

Transcription factors associated with Rfx2_Rfx7

Gene Symbol Gene ID Gene Info
ENSMUSG00000024206.16 regulatory factor X, 2 (influences HLA class II expression)
ENSMUSG00000037674.16 regulatory factor X, 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rfx7mm39_v1_chr9_+_72439496_72439553-0.464.7e-03Click!
Rfx2mm39_v1_chr17_-_57137898_571380130.183.0e-01Click!

Activity profile of Rfx2_Rfx7 motif

Sorted Z-values of Rfx2_Rfx7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_44117444 5.91 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josephin domain containing 2
chr7_+_44117511 5.58 ENSMUST00000121922.3
ENSMUST00000208117.2
Josephin domain containing 2
chr7_+_44117475 5.06 ENSMUST00000118493.8
Josephin domain containing 2
chr7_+_44117404 4.11 ENSMUST00000035844.11
Josephin domain containing 2
chr10_-_62258195 2.67 ENSMUST00000020277.9
hexokinase domain containing 1
chr11_+_114618209 1.69 ENSMUST00000069325.14
dynein axonemal intermediate chain 2
chr11_-_120715351 1.55 ENSMUST00000055655.9
fatty acid synthase
chr7_+_140774962 1.55 ENSMUST00000047093.11
leucine rich repeat containing 56
chr2_-_152673585 1.49 ENSMUST00000156688.2
ENSMUST00000007803.12
BCL2-like 1
chr7_-_4687916 1.42 ENSMUST00000206306.2
ENSMUST00000205952.2
ENSMUST00000079970.6
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr7_+_140711181 1.33 ENSMUST00000026568.10
phosphatidylserine synthase 2
chr8_+_112667328 1.31 ENSMUST00000034428.8
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
chr1_-_131065967 1.20 ENSMUST00000189756.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr7_+_24246575 1.20 ENSMUST00000063249.9
X-ray repair complementing defective repair in Chinese hamster cells 1
chr1_-_131066004 1.20 ENSMUST00000016670.9
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr8_-_71245036 1.17 ENSMUST00000212038.2
ENSMUST00000212551.2
ENSMUST00000211948.2
microtubule associated serine/threonine kinase 3
chr10_-_93425553 1.16 ENSMUST00000020203.7
small nuclear ribonucleoprotein polypeptide F
chr7_-_132415528 1.06 ENSMUST00000097998.9
family with sequence similarity 53, member B
chr11_-_5900019 1.02 ENSMUST00000102920.4
glucokinase
chr12_-_40088024 0.95 ENSMUST00000101472.4
ADP-ribosylation factor-like 4A
chr2_-_152673032 0.93 ENSMUST00000128172.3
BCL2-like 1
chr11_-_116472272 0.92 ENSMUST00000082152.5
ubiquitin-conjugating enzyme E2O
chr15_-_81810349 0.91 ENSMUST00000023113.7
polymerase (RNA) III (DNA directed) polypeptide H
chr5_-_117527094 0.89 ENSMUST00000111953.2
ENSMUST00000086461.13
replication factor C (activator 1) 5
chr8_+_39472981 0.83 ENSMUST00000239508.1
ENSMUST00000239509.1
tumor suppressor candidate 3
chr11_+_102772030 0.78 ENSMUST00000021307.10
ENSMUST00000159834.2
coiled-coil domain containing 103
chr7_-_44542098 0.78 ENSMUST00000003049.8
mediator complex subunit 25
chr3_-_50398027 0.77 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr4_+_134591847 0.68 ENSMUST00000030627.8
Rh blood group, D antigen
chr11_+_117006020 0.65 ENSMUST00000103026.10
ENSMUST00000090433.6
SEC14-like lipid binding 1
chr11_-_53371050 0.65 ENSMUST00000104955.4
sosondowah ankyrin repeat domain family member A
chr11_-_102771751 0.65 ENSMUST00000021306.14
elongation factor Tu GTP binding domain containing 2
chr9_-_21202353 0.64 ENSMUST00000086374.8
cyclin dependent kinase inhibitor 2D
chr9_-_21913896 0.64 ENSMUST00000044926.6
outer dynein arm docking complex subunit 3
chr4_+_6191084 0.63 ENSMUST00000029907.6
UBX domain protein 2B
chr9_-_21202545 0.63 ENSMUST00000215619.2
cyclin dependent kinase inhibitor 2D
chr7_+_18810097 0.63 ENSMUST00000032570.14
dystrophia myotonica-containing WD repeat motif
chr2_+_162916551 0.62 ENSMUST00000142729.3
myeloblastosis oncogene-like 2
chr17_+_34823236 0.62 ENSMUST00000174041.8
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr8_+_41246310 0.61 ENSMUST00000056331.8
a disintegrin and metallopeptidase domain 20
chr2_+_32665781 0.60 ENSMUST00000066352.6
peptidyl-tRNA hydrolase 1 homolog
chr7_-_45463701 0.60 ENSMUST00000210898.2
ENSMUST00000107729.10
ENSMUST00000056820.13
cytohesin 2
chrX_-_93410383 0.59 ENSMUST00000044989.12
family with sequence similarity 90, member A1B
chr9_+_72345801 0.59 ENSMUST00000184604.8
ENSMUST00000034746.10
meiosis-specific nuclear structural protein 1
chr5_+_30486375 0.59 ENSMUST00000101448.5
dynein regulatory complex subunit 1
chr11_-_102771806 0.58 ENSMUST00000107060.8
elongation factor Tu GTP binding domain containing 2
chr11_-_78056347 0.58 ENSMUST00000017530.4
TNF receptor associated factor 4
chr2_-_32665637 0.58 ENSMUST00000161958.2
tetratricopeptide repeat domain 16
chr10_+_79505203 0.57 ENSMUST00000020552.8
ENSMUST00000239401.2
tubulin polyglutamylase complex subunit 1
chr4_+_137989526 0.57 ENSMUST00000030539.10
kinesin family member 17
chr3_-_75389047 0.56 ENSMUST00000193989.4
ENSMUST00000203169.3
WD repeat domain 49
chr17_+_25690538 0.56 ENSMUST00000234449.2
ENSMUST00000025002.3
ENSMUST00000235033.2
tektin 4
chr11_+_117005958 0.56 ENSMUST00000021177.15
SEC14-like lipid binding 1
chr9_-_21202693 0.55 ENSMUST00000213407.2
cyclin dependent kinase inhibitor 2D
chr2_-_93292800 0.54 ENSMUST00000028644.11
CD82 antigen
chr8_-_106434565 0.54 ENSMUST00000013299.11
enkurin domain containing 1
chr19_+_9979033 0.54 ENSMUST00000121418.8
RAB3A interacting protein (rabin3)-like 1
chr4_+_137989783 0.53 ENSMUST00000105821.3
kinesin family member 17
chr9_-_21913833 0.53 ENSMUST00000115336.10
outer dynein arm docking complex subunit 3
chr2_-_32665596 0.53 ENSMUST00000161430.8
tetratricopeptide repeat domain 16
chr19_-_10460238 0.53 ENSMUST00000235392.2
ENSMUST00000237522.2
ENSMUST00000038842.5
protein phosphatase 1, regulatory subunit 32
chr5_-_21850579 0.51 ENSMUST00000051358.11
F-box and leucine-rich repeat protein 13
chr19_+_47926086 0.51 ENSMUST00000238163.2
ENSMUST00000066308.9
cilia and flagella associated protein 58
chr8_+_41205245 0.51 ENSMUST00000096663.5
a disintegrin and metallopeptidase domain 25 (testase 2)
chr5_-_21850539 0.51 ENSMUST00000115234.2
F-box and leucine-rich repeat protein 13
chr13_-_55684317 0.50 ENSMUST00000021956.9
ENSMUST00000224765.2
DEAD box helicase 41
chr7_+_100145192 0.49 ENSMUST00000133044.3
uncoupling protein 2 (mitochondrial, proton carrier)
chr8_-_123170102 0.49 ENSMUST00000006692.6
mevalonate (diphospho) decarboxylase
chr7_-_125090540 0.48 ENSMUST00000138616.3
NSE1 homolog, SMC5-SMC6 complex component
chr1_+_46105898 0.48 ENSMUST00000069293.10
dynein, axonemal, heavy chain 7B
chr1_-_133728779 0.47 ENSMUST00000143567.8
ATPase, Ca++ transporting, plasma membrane 4
chr7_+_44545501 0.47 ENSMUST00000071207.14
ENSMUST00000209132.2
ENSMUST00000207069.2
ENSMUST00000209039.2
ENSMUST00000207939.3
ENSMUST00000207485.2
ENSMUST00000208179.2
fuzzy planar cell polarity protein
chr2_+_70339157 0.46 ENSMUST00000100041.9
glutamate rich 2
chr7_-_125090757 0.46 ENSMUST00000033006.14
NSE1 homolog, SMC5-SMC6 complex component
chr2_+_30331839 0.46 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr2_+_70339175 0.46 ENSMUST00000134607.8
glutamate rich 2
chr14_+_55855484 0.45 ENSMUST00000002395.8
REC8 meiotic recombination protein
chr7_+_4925781 0.45 ENSMUST00000207527.2
ENSMUST00000207687.2
ENSMUST00000208754.2
N-acetyltransferase 14
chr11_-_66059330 0.45 ENSMUST00000080665.10
dynein, axonemal, heavy chain 9
chr11_-_66059270 0.45 ENSMUST00000108691.2
dynein, axonemal, heavy chain 9
chr17_+_69144053 0.44 ENSMUST00000178545.3
transmembrane protein 200C
chr11_+_101358990 0.44 ENSMUST00000001347.7
Rho family GTPase 2
chr2_-_151822114 0.44 ENSMUST00000062047.6
family with sequence similarity 110, member A
chr14_-_56339915 0.44 ENSMUST00000015583.2
cathepsin G
chr7_+_26932425 0.44 ENSMUST00000003860.13
ENSMUST00000108378.10
coenzyme Q8B
chr11_+_100436433 0.43 ENSMUST00000092684.12
ENSMUST00000006976.8
outer dynein arm complex subunit 4
chr1_+_46106006 0.43 ENSMUST00000238212.2
dynein, axonemal, heavy chain 7B
chr17_+_71980249 0.43 ENSMUST00000097284.10
TOG array regulator of axonemal microtubules 2
chr14_+_46997984 0.42 ENSMUST00000067426.6
cyclin-dependent kinase inhibitor 3
chr11_+_78068931 0.42 ENSMUST00000147819.8
TLC domain containing 1
chr7_+_126575510 0.42 ENSMUST00000206780.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr5_-_108922819 0.42 ENSMUST00000200159.2
ENSMUST00000212212.2
ring finger protein 212
chr4_-_117109074 0.42 ENSMUST00000165128.9
armadillo-like helical domain containing 1
chr6_-_87699767 0.42 ENSMUST00000238521.2
Riken cDNA 1810020O05 gene
chr7_-_55669702 0.42 ENSMUST00000052204.6
non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)
chr8_-_85751897 0.42 ENSMUST00000064314.10
guided entry of tail-anchored proteins factor 3, ATPase
chr15_-_54953819 0.41 ENSMUST00000110231.2
ENSMUST00000023059.13
DNA replication and sister chromatid cohesion 1
chr12_+_111132779 0.41 ENSMUST00000117269.8
TNF receptor-associated factor 3
chr3_+_82265351 0.40 ENSMUST00000193559.6
ENSMUST00000192595.6
ENSMUST00000091014.10
microtubule-associated protein 9
chr9_+_22322802 0.40 ENSMUST00000058868.9
RIKEN cDNA 9530077C05 gene
chr3_+_146110709 0.39 ENSMUST00000129978.2
synovial sarcoma, X 2 interacting protein
chrX_+_71962157 0.39 ENSMUST00000033715.5
NAD(P) dependent steroid dehydrogenase-like
chr11_+_68477812 0.39 ENSMUST00000154294.8
ENSMUST00000063006.12
coiled-coil domain containing 42
chr10_+_57521930 0.39 ENSMUST00000177325.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr11_+_97697128 0.38 ENSMUST00000138919.2
LIM and SH3 protein 1
chr17_-_11059172 0.38 ENSMUST00000041463.7
PARK2 co-regulated
chr9_+_72345267 0.38 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chr8_-_79975199 0.37 ENSMUST00000034109.6
RIKEN cDNA 1700011L22 gene
chr8_-_55177510 0.37 ENSMUST00000175915.8
WD repeat domain 17
chr17_-_46558894 0.37 ENSMUST00000142706.9
ENSMUST00000173349.8
ENSMUST00000087026.13
polymerase (RNA) I polypeptide C
chr7_-_28465870 0.37 ENSMUST00000085851.12
ENSMUST00000032815.11
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
chr11_-_117673008 0.37 ENSMUST00000152304.3
transmembrane channel-like gene family 6
chr1_-_16163506 0.37 ENSMUST00000145070.8
ENSMUST00000151004.2
RIKEN cDNA 4930444P10 gene
chr12_-_85335193 0.37 ENSMUST00000121930.2
acylphosphatase 1, erythrocyte (common) type
chr1_-_119764729 0.37 ENSMUST00000163621.2
ENSMUST00000168303.8
protein tyrosine phosphatase, non-receptor type 4
chr16_+_36832119 0.37 ENSMUST00000071452.12
ENSMUST00000054034.7
polymerase (DNA directed), theta
chr3_+_156267429 0.37 ENSMUST00000074015.11
neuronal growth regulator 1
chr5_-_149559667 0.36 ENSMUST00000074846.14
heat shock 105kDa/110kDa protein 1
chr9_+_49014020 0.36 ENSMUST00000070390.12
ENSMUST00000167095.8
transmembrane protease, serine 5 (spinesin)
chr11_+_115802828 0.36 ENSMUST00000132961.2
small integral membrane protein 6
chr5_-_116427003 0.36 ENSMUST00000086483.4
ENSMUST00000050178.13
coiled-coil domain containing 60
chr8_+_72993862 0.36 ENSMUST00000003117.15
ENSMUST00000212841.2
adaptor-related protein complex AP-1, mu subunit 1
chr7_+_18810167 0.35 ENSMUST00000108479.2
dystrophia myotonica-containing WD repeat motif
chr4_+_100336003 0.35 ENSMUST00000133493.9
ENSMUST00000092730.5
ubiquitin-conjugating enzyme E2U (putative)
chr5_+_30623379 0.35 ENSMUST00000127815.2
ENSMUST00000031078.10
ENSMUST00000114743.2
family with sequence similarity 166, member C
chr9_-_21061196 0.35 ENSMUST00000215296.2
ENSMUST00000019615.11
cell division cycle 37
chr14_-_64225223 0.35 ENSMUST00000022532.6
RIKEN cDNA 4930578I06 gene
chr8_-_55177352 0.35 ENSMUST00000129132.3
ENSMUST00000150488.8
ENSMUST00000127511.9
WD repeat domain 17
chr11_-_69470139 0.34 ENSMUST00000048139.12
WD repeat containing, antisense to Trp53
chr11_+_62441992 0.34 ENSMUST00000019649.4
ubiquitin B
chr7_-_79882313 0.34 ENSMUST00000206084.2
ENSMUST00000205996.2
ENSMUST00000071457.12
calcium and integrin binding 1 (calmyrin)
chr12_+_111132847 0.34 ENSMUST00000021706.11
TNF receptor-associated factor 3
chr11_-_30421792 0.34 ENSMUST00000041763.14
RIKEN cDNA 4930505A04 gene
chr3_+_82265474 0.34 ENSMUST00000195471.6
ENSMUST00000195640.2
microtubule-associated protein 9
chr3_+_146110387 0.33 ENSMUST00000106151.8
ENSMUST00000106153.9
ENSMUST00000039021.11
ENSMUST00000106149.8
ENSMUST00000149262.8
synovial sarcoma, X 2 interacting protein
chr6_-_38852857 0.33 ENSMUST00000162359.8
homeodomain interacting protein kinase 2
chr1_-_53745920 0.33 ENSMUST00000094964.7
dynein, axonemal, heavy chain 7A
chr9_+_119766672 0.32 ENSMUST00000035100.6
tetratricopeptide repeat domain 21A
chr6_-_8259098 0.32 ENSMUST00000012627.5
replication protein A3
chr15_+_78798116 0.32 ENSMUST00000089378.5
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr6_+_128352419 0.32 ENSMUST00000130785.4
ENSMUST00000100926.4
ENSMUST00000204223.2
testis expressed 52
predicted gene 44596
chr11_+_59839032 0.32 ENSMUST00000081980.7
mediator complex subunit 9
chr6_-_38852899 0.32 ENSMUST00000160360.2
homeodomain interacting protein kinase 2
chr14_+_46998004 0.32 ENSMUST00000227149.2
cyclin-dependent kinase inhibitor 3
chr2_-_35226981 0.32 ENSMUST00000028241.7
stomatin
chr12_+_87247297 0.32 ENSMUST00000182869.2
sterile alpha motif domain containing 15
chr5_-_149559792 0.32 ENSMUST00000202361.4
ENSMUST00000202089.4
ENSMUST00000200825.2
ENSMUST00000201559.4
heat shock 105kDa/110kDa protein 1
chr3_+_75655504 0.32 ENSMUST00000189155.4
predicted gene 29133
chr5_+_120727068 0.31 ENSMUST00000069259.9
ENSMUST00000094391.6
IQ motif containing D
chr1_-_119765068 0.31 ENSMUST00000163435.8
protein tyrosine phosphatase, non-receptor type 4
chr12_+_113149487 0.31 ENSMUST00000058491.8
transmembrane protein 121
chr10_+_57521958 0.31 ENSMUST00000177473.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr17_-_34822649 0.31 ENSMUST00000015622.8
ring finger protein 5
chr12_+_33444853 0.31 ENSMUST00000020878.8
EF-hand calcium binding domain 10
chr6_-_113577606 0.31 ENSMUST00000035870.5
Fancd2 opposite strand
chr1_+_60448931 0.30 ENSMUST00000189082.7
ENSMUST00000187709.7
abl interactor 2
chr5_+_27466914 0.30 ENSMUST00000101471.4
dipeptidylpeptidase 6
chr7_-_143153785 0.30 ENSMUST00000105909.4
ENSMUST00000010899.14
cysteinyl-tRNA synthetase
chr7_+_4785936 0.30 ENSMUST00000013235.6
transmembrane protein 190
chr11_+_11414256 0.29 ENSMUST00000020410.11
spermatogenesis associated 48
chr5_+_123627365 0.29 ENSMUST00000196809.5
ENSMUST00000094327.10
ENSMUST00000121444.2
leucine rich repeat containing 43
chr10_-_22607136 0.29 ENSMUST00000238910.2
ENSMUST00000127698.8
novel protein
TATA box binding protein-like 1
chr4_+_118266526 0.29 ENSMUST00000084319.11
ENSMUST00000106384.10
ENSMUST00000126089.8
ENSMUST00000073881.8
ENSMUST00000019229.15
mediator complex subunit 8
chr2_-_164876690 0.29 ENSMUST00000122070.2
ENSMUST00000121377.8
ENSMUST00000153905.2
ENSMUST00000040381.15
nuclear receptor coactivator 5
chr18_+_57666852 0.29 ENSMUST00000079738.10
ENSMUST00000135806.8
ENSMUST00000127130.9
coiled-coil domain containing 192
chr2_-_181340226 0.29 ENSMUST00000052416.4
LKAAEAR motif containing 1 (IKAAEAR murine motif)
chr11_+_117672902 0.29 ENSMUST00000127080.9
transmembrane channel-like gene family 8
chr9_-_103569984 0.29 ENSMUST00000049452.15
transmembrane protein 108
chr2_-_69619864 0.29 ENSMUST00000094942.4
coiled-coil domain containing 173
chr7_-_28297565 0.28 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr2_-_152239966 0.28 ENSMUST00000063332.9
ENSMUST00000182625.2
SRY (sex determining region Y)-box 12
chr5_+_124802149 0.28 ENSMUST00000141137.7
ENSMUST00000058440.12
dynein, axonemal, heavy chain 10
chr6_+_85564566 0.28 ENSMUST00000213058.2
ALMS1, centrosome and basal body associated
chr10_-_74868360 0.28 ENSMUST00000159994.2
ENSMUST00000179546.8
ENSMUST00000160450.8
ENSMUST00000160072.8
ENSMUST00000009214.10
ENSMUST00000166088.8
radial spoke head homolog 14 (Chlamydomonas)
chr8_+_27937691 0.28 ENSMUST00000081321.5
POTE ankyrin domain family, member G
chr5_+_135807334 0.27 ENSMUST00000019323.11
malate dehydrogenase 2, NAD (mitochondrial)
chr2_-_71377088 0.27 ENSMUST00000024159.8
distal-less homeobox 2
chr5_-_149559636 0.27 ENSMUST00000201452.4
heat shock 105kDa/110kDa protein 1
chr15_+_85016261 0.27 ENSMUST00000023067.4
RIB43A domain with coiled-coils 2
chr7_+_90075762 0.27 ENSMUST00000061391.9
coiled-coil domain containing 89
chr11_-_119190896 0.27 ENSMUST00000026667.15
eukaryotic translation initiation factor 4A3
chr7_-_79882501 0.27 ENSMUST00000065163.15
calcium and integrin binding 1 (calmyrin)
chr8_+_106434901 0.27 ENSMUST00000013302.7
ENSMUST00000211852.2
RIKEN cDNA 4933405L10 gene
chr19_+_34078333 0.26 ENSMUST00000025685.8
lipase, family member M
chr6_-_24515036 0.26 ENSMUST00000052277.5
IQ motif and ubiquitin domain containing
chr3_+_156267587 0.26 ENSMUST00000041425.12
ENSMUST00000106065.2
neuronal growth regulator 1
chr1_+_191553556 0.26 ENSMUST00000027931.8
NIMA (never in mitosis gene a)-related expressed kinase 2
chr5_+_77163869 0.26 ENSMUST00000031161.11
ENSMUST00000117880.8
theg spermatid protein like
chr14_-_29443792 0.26 ENSMUST00000022567.9
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr8_+_123844090 0.25 ENSMUST00000037900.9
copine VII
chr15_-_89263466 0.25 ENSMUST00000228111.2
outer dense fiber of sperm tails 3B
chr7_-_127187767 0.25 ENSMUST00000072155.5
coiled-coil domain containing 189
chr7_-_44541787 0.25 ENSMUST00000208551.2
ENSMUST00000208253.2
ENSMUST00000207654.2
ENSMUST00000207278.2
mediator complex subunit 25
chr7_+_3632982 0.25 ENSMUST00000179769.8
ENSMUST00000008517.13
pre-mRNA processing factor 31
chr6_+_83055321 0.25 ENSMUST00000165164.9
ENSMUST00000092614.9
polycomb group ring finger 1
chr16_-_3725515 0.25 ENSMUST00000177221.2
ENSMUST00000177323.8
RIKEN cDNA 1700037C18 gene
chr5_+_98477157 0.25 ENSMUST00000080333.8
cilia and flagella associated protein 299
chr12_+_113120023 0.25 ENSMUST00000049271.13
tubulin epsilon and delta complex 1
chr4_+_118266582 0.25 ENSMUST00000144577.2
mediator complex subunit 8
chr6_-_73198608 0.25 ENSMUST00000064948.13
ENSMUST00000114040.8
dynein, axonemal, heavy chain 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Rfx2_Rfx7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0046898 response to cycloheximide(GO:0046898)
0.5 2.4 GO:0035617 stress granule disassembly(GO:0035617)
0.3 1.0 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.2 1.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 1.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 1.6 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2 0.8 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 1.2 GO:0015871 choline transport(GO:0015871)
0.2 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.5 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 0.5 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2 1.1 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 0.5 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.2 2.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0080154 regulation of fertilization(GO:0080154)
0.1 21.0 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 1.8 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.5 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.3 GO:0046038 GMP catabolic process(GO:0046038)
0.1 0.6 GO:0032202 telomere assembly(GO:0032202)
0.1 0.3 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.1 2.4 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 0.3 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 0.3 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0035822 meiotic gene conversion(GO:0006311) gene conversion(GO:0035822)
0.1 1.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.2 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0007144 female meiosis I(GO:0007144)
0.0 2.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0061193 taste bud development(GO:0061193)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.4 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.2 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.9 GO:0006301 postreplication repair(GO:0006301)
0.0 1.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0061090 positive regulation of sequestering of zinc ion(GO:0061090)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.4 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 1.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0007141 male meiosis I(GO:0007141)
0.0 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0006348 DNA replication-dependent nucleosome assembly(GO:0006335) chromatin silencing at telomere(GO:0006348) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685) termination of signal transduction(GO:0023021)
0.0 0.2 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.8 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.0 0.1 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.2 GO:0005683 U7 snRNP(GO:0005683)
0.2 2.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.2 2.0 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.6 GO:0042587 glycogen granule(GO:0042587)
0.1 1.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 0.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.3 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.3 GO:0017177 glucosidase II complex(GO:0017177)
0.1 0.3 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.2 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031177 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) phosphopantetheine binding(GO:0031177)
0.4 3.7 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.2 2.4 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 20.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 0.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 1.5 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.7 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.3 GO:0030622 U4atac snRNA binding(GO:0030622)
0.1 0.2 GO:0008456 alpha-N-acetylgalactosaminidase activity(GO:0008456)
0.1 0.3 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0002046 opsin binding(GO:0002046)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 2.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.0 GO:0019809 spermidine binding(GO:0019809)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis