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GSE58827: Dynamics of the Mouse Liver

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Results for Rhox4e_Rhox6_Vax2

Z-value: 0.65

Motif logo

Transcription factors associated with Rhox4e_Rhox6_Vax2

Gene Symbol Gene ID Gene Info
ENSMUSG00000071770.6 reproductive homeobox 4E
ENSMUSG00000006200.4 reproductive homeobox 6
ENSMUSG00000034777.3 ventral anterior homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rhox4emm39_v1_chrX_+_36739065_36739065-0.153.9e-01Click!
Vax2mm39_v1_chr6_+_83688213_836882700.144.0e-01Click!

Activity profile of Rhox4e_Rhox6_Vax2 motif

Sorted Z-values of Rhox4e_Rhox6_Vax2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127734384 5.05 ENSMUST00000047134.8
4short chain dehydrogenase/reductase family 9C, member 7
chr7_+_51528788 5.01 ENSMUST00000107591.9
growth arrest specific 2
chr6_+_121815473 4.26 ENSMUST00000032228.9
murinoglobulin 1
chr19_-_39637489 4.09 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr3_-_67422821 3.76 ENSMUST00000054825.5
retinoic acid receptor responder (tazarotene induced) 1
chr16_+_22737128 3.64 ENSMUST00000170805.9
fetuin beta
chr16_+_22737227 3.54 ENSMUST00000231880.2
fetuin beta
chr16_+_22737050 3.50 ENSMUST00000231768.2
fetuin beta
chr8_+_46111703 3.48 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
sorbin and SH3 domain containing 2
chr4_+_43493344 3.41 ENSMUST00000030181.12
ENSMUST00000107922.3
coiled-coil domain containing 107
chr6_+_121983720 3.36 ENSMUST00000081777.8
murinoglobulin 2
chr15_+_59186876 2.74 ENSMUST00000022977.14
ENSMUST00000100640.5
squalene epoxidase
chr11_-_113600838 2.41 ENSMUST00000018871.8
cleavage and polyadenylation specific factor 4-like
chr2_+_69727563 2.20 ENSMUST00000055758.16
ENSMUST00000112251.9
ubiquitin protein ligase E3 component n-recognin 3
chr5_-_87240405 2.06 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr2_+_172994841 1.80 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr19_-_39801188 1.79 ENSMUST00000162507.2
ENSMUST00000160476.9
ENSMUST00000239028.2
cytochrome P450, family 2, subfamily c, polypeptide 40
chr2_+_69727599 1.66 ENSMUST00000131553.2
ubiquitin protein ligase E3 component n-recognin 3
chr13_+_24023428 1.65 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
solute carrier family 17 (sodium phosphate), member 3
chr5_+_90708962 1.57 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr12_-_79237722 1.52 ENSMUST00000085254.7
retinol dehydrogenase 11
chr2_-_154916367 1.40 ENSMUST00000137242.2
ENSMUST00000054607.16
S-adenosylhomocysteine hydrolase
chrX_+_102400061 1.36 ENSMUST00000116547.3
cysteine-rich hydrophobic domain 1
chr13_+_24023386 1.24 ENSMUST00000039721.14
solute carrier family 17 (sodium phosphate), member 3
chr14_-_45626237 1.23 ENSMUST00000227865.2
ENSMUST00000226856.2
ENSMUST00000226276.2
ENSMUST00000046191.9
glucosamine-phosphate N-acetyltransferase 1
chr7_-_12829100 1.22 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chrM_+_8603 1.20 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr8_+_45960804 1.20 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr13_-_53627110 1.20 ENSMUST00000021922.10
msh homeobox 2
chr5_-_87402659 1.13 ENSMUST00000075858.4
UDP glucuronosyltransferase 2 family, polypeptide B37
chr18_-_10706701 1.09 ENSMUST00000002549.9
ENSMUST00000117726.9
ENSMUST00000117828.9
abhydrolase domain containing 3
chr11_+_58062467 1.07 ENSMUST00000020820.2
mitochondrial ribosomal protein L22
chr7_-_126275529 1.04 ENSMUST00000106372.11
ENSMUST00000155419.3
ENSMUST00000106373.9
sulfotransferase family 1A, phenol-preferring, member 1
chrM_+_10167 1.04 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr4_+_100336003 1.01 ENSMUST00000133493.9
ENSMUST00000092730.5
ubiquitin-conjugating enzyme E2U (putative)
chr8_+_45960931 1.00 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr6_-_125357756 1.00 ENSMUST00000042647.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr10_-_81243475 1.00 ENSMUST00000140916.8
nuclear factor I/C
chr9_+_21634779 0.96 ENSMUST00000034713.9
low density lipoprotein receptor
chr4_-_14621805 0.95 ENSMUST00000042221.14
solute carrier family 26, member 7
chr18_+_60515755 0.95 ENSMUST00000237185.2
interferon inducible GTPase 1
chr9_-_71070506 0.94 ENSMUST00000074465.9
aquaporin 9
chr1_+_87983099 0.93 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr10_-_126956991 0.90 ENSMUST00000080975.6
ENSMUST00000164259.9
amplified in osteosarcoma
chr18_+_60345152 0.90 ENSMUST00000031549.6
predicted gene 4951
chr18_+_12874390 0.90 ENSMUST00000121018.8
ENSMUST00000119108.8
ENSMUST00000186263.2
ENSMUST00000191078.7
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr1_-_72323464 0.88 ENSMUST00000027381.13
peroxisomal trans-2-enoyl-CoA reductase
chr1_-_72323407 0.87 ENSMUST00000097698.5
peroxisomal trans-2-enoyl-CoA reductase
chr2_+_163348728 0.87 ENSMUST00000143911.8
hepatic nuclear factor 4, alpha
chr4_-_14621669 0.86 ENSMUST00000143105.2
solute carrier family 26, member 7
chr4_-_129121676 0.81 ENSMUST00000106051.8
expressed sequence C77080
chr2_-_132089667 0.81 ENSMUST00000110163.8
ENSMUST00000180286.2
ENSMUST00000028816.9
transmembrane protein 230
chr10_+_127226180 0.81 ENSMUST00000077046.12
ENSMUST00000105250.9
R3H domain containing 2
chrM_+_7758 0.80 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr8_+_46111778 0.80 ENSMUST00000143820.8
sorbin and SH3 domain containing 2
chr5_+_104350475 0.78 ENSMUST00000066708.7
dentin matrix protein 1
chr1_+_87983189 0.77 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr9_+_80072361 0.76 ENSMUST00000184480.8
myosin VI
chr17_-_59320257 0.76 ENSMUST00000174122.2
ENSMUST00000025065.12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr17_+_79919267 0.74 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chrM_+_9870 0.73 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr15_-_74508197 0.73 ENSMUST00000023271.8
maestro heat-like repeat family member 4
chr9_-_50472605 0.72 ENSMUST00000034568.7
testis expressed 12
chr14_-_45626198 0.72 ENSMUST00000226590.2
glucosamine-phosphate N-acetyltransferase 1
chr7_-_28855143 0.72 ENSMUST00000153251.8
family with sequence similarity 98, member C
chr4_-_133066594 0.72 ENSMUST00000043305.14
WD and tetratricopeptide repeats 1
chrM_+_7779 0.71 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chrM_+_2743 0.70 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr9_-_50472620 0.69 ENSMUST00000217236.2
testis expressed 12
chr9_-_65792306 0.64 ENSMUST00000122410.8
ENSMUST00000117083.2
thyroid hormone receptor interactor 4
chr18_+_38551960 0.63 ENSMUST00000236085.2
Nedd4 family interacting protein 1
chr16_+_18655318 0.62 ENSMUST00000055413.13
ENSMUST00000123146.8
ENSMUST00000191388.2
RIKEN cDNA 2510002D24 gene
chr13_-_103042294 0.60 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr19_-_39875192 0.58 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr14_-_68771138 0.58 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr19_+_60800012 0.58 ENSMUST00000128357.8
ENSMUST00000119633.8
ENSMUST00000025957.9
DENN domain containing 10
chr13_-_17869314 0.57 ENSMUST00000221598.2
ENSMUST00000068545.6
ENSMUST00000220514.2
succinyl-CoA glutarate-CoA transferase
chr18_+_12874368 0.56 ENSMUST00000235000.2
ENSMUST00000115857.9
calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chrM_+_14138 0.55 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr18_+_38552011 0.55 ENSMUST00000025293.5
Nedd4 family interacting protein 1
chr19_-_44095840 0.55 ENSMUST00000119591.2
ENSMUST00000026217.11
conserved helix-loop-helix ubiquitous kinase
chrX_+_106299484 0.54 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chrM_+_7006 0.53 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr6_-_115569504 0.52 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr7_-_28855020 0.52 ENSMUST00000123416.2
family with sequence similarity 98, member C
chr15_-_66985760 0.50 ENSMUST00000092640.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr7_+_28869770 0.50 ENSMUST00000033886.8
ENSMUST00000209019.2
ENSMUST00000208330.2
gametogenetin
chr4_-_14621497 0.50 ENSMUST00000149633.2
solute carrier family 26, member 7
chr10_+_29074950 0.49 ENSMUST00000217011.2
predicted gene, 49353
chr5_-_3697806 0.49 ENSMUST00000119783.2
ENSMUST00000007559.15
GATA zinc finger domain containing 1
chr3_+_121746862 0.48 ENSMUST00000037958.14
ENSMUST00000196904.5
Rho GTPase activating protein 29
chr5_-_118382926 0.47 ENSMUST00000117177.8
ENSMUST00000133372.2
ENSMUST00000154786.8
ENSMUST00000121369.8
ring finger protein, transmembrane 2
chr10_+_23770586 0.47 ENSMUST00000041416.8
vanin 1
chr13_-_103042554 0.47 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr7_-_24423715 0.46 ENSMUST00000081657.6
Ly6/PLAUR domain containing 11
chr6_-_41752111 0.46 ENSMUST00000214976.3
olfactory receptor 459
chr12_-_85871281 0.45 ENSMUST00000021676.12
ENSMUST00000142331.2
ergosterol biosynthesis 28
chr7_+_28869629 0.45 ENSMUST00000098609.4
gametogenetin
chr9_+_108216466 0.45 ENSMUST00000193987.2
glutathione peroxidase 1
chr8_+_45960855 0.45 ENSMUST00000141039.8
sorbin and SH3 domain containing 2
chr12_+_80690985 0.44 ENSMUST00000219405.2
ENSMUST00000085245.7
solute carrier family 39 (zinc transporter), member 9
chr6_+_145879839 0.43 ENSMUST00000032383.14
sarcospan
chr4_+_15881256 0.43 ENSMUST00000029876.2
calbindin 1
chr12_-_84664001 0.42 ENSMUST00000221070.2
ENSMUST00000021666.6
ENSMUST00000223107.2
ATP-binding cassette, sub-family D (ALD), member 4
chr16_-_29363671 0.42 ENSMUST00000039090.9
ATPase type 13A4
chr2_-_69542805 0.42 ENSMUST00000102706.4
ENSMUST00000073152.13
FAST kinase domains 1
chr1_+_163757334 0.41 ENSMUST00000027876.11
ENSMUST00000170359.8
SCY1-like 3 (S. cerevisiae)
chr12_+_55350023 0.41 ENSMUST00000184766.8
ENSMUST00000183475.8
ENSMUST00000183654.2
protein only RNase P catalytic subunit
chr1_+_88234454 0.40 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr7_-_46316767 0.40 ENSMUST00000168335.3
ENSMUST00000107669.9
tryptophan hydroxylase 1
chr7_+_130375799 0.40 ENSMUST00000048453.7
ENSMUST00000208593.2
BTB (POZ) domain containing 16
chr19_+_3373285 0.39 ENSMUST00000025835.6
carnitine palmitoyltransferase 1a, liver
chr9_+_108216433 0.39 ENSMUST00000191997.2
glutathione peroxidase 1
chr11_-_99241924 0.37 ENSMUST00000017732.3
keratin 27
chr10_-_44024843 0.37 ENSMUST00000200401.2
crystallin beta-gamma domain containing 1
chr9_-_55419442 0.37 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr13_-_81859056 0.36 ENSMUST00000161920.2
ENSMUST00000048993.12
polymerase (RNA) III (DNA directed) polypeptide G
chr12_+_55349422 0.36 ENSMUST00000021411.15
protein only RNase P catalytic subunit
chr19_+_25384024 0.35 ENSMUST00000146647.3
KN motif and ankyrin repeat domains 1
chrM_-_14061 0.35 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr11_+_50917831 0.35 ENSMUST00000072152.2
olfactory receptor 54
chr15_+_98350469 0.33 ENSMUST00000217517.2
olfactory receptor 281
chr2_+_177760959 0.31 ENSMUST00000108916.8
phosphatase and actin regulator 3
chr13_+_90237824 0.31 ENSMUST00000012566.9
transmembrane protein 167
chr4_+_108576846 0.31 ENSMUST00000178992.2
RIKEN cDNA 3110021N24 gene
chr9_+_72866067 0.30 ENSMUST00000098567.9
ENSMUST00000034734.9
dynein axonemal assembly factor 4
chr1_-_63215952 0.30 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr3_-_54962899 0.30 ENSMUST00000199144.5
cyclin A1
chr7_+_30157704 0.30 ENSMUST00000126297.9
nephrosis 1, nephrin
chr2_+_127696548 0.30 ENSMUST00000028859.8
acyl-Coenzyme A oxidase-like
chr2_+_121787131 0.29 ENSMUST00000110574.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_+_173964312 0.29 ENSMUST00000053941.4
olfactory receptor 424
chr19_-_7943365 0.29 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chrX_-_158921370 0.29 ENSMUST00000033662.9
pyruvate dehydrogenase E1 alpha 1
chr4_+_122910382 0.29 ENSMUST00000102649.4
tRNA isopentenyltransferase 1
chr5_-_90788323 0.28 ENSMUST00000202784.4
ENSMUST00000031317.10
ENSMUST00000201370.2
Ras association (RalGDS/AF-6) domain family member 6
chr8_-_62355690 0.28 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr5_-_84565218 0.28 ENSMUST00000113401.4
Eph receptor A5
chr9_+_108216233 0.28 ENSMUST00000082429.8
glutathione peroxidase 1
chr5_+_29400981 0.28 ENSMUST00000160888.8
ENSMUST00000159272.8
ENSMUST00000001247.12
ENSMUST00000161398.8
ENSMUST00000160246.8
ring finger protein 32
chr12_+_116239006 0.27 ENSMUST00000090195.5
predicted gene 11027
chr1_+_135768409 0.27 ENSMUST00000189826.7
troponin T2, cardiac
chr7_+_114344920 0.27 ENSMUST00000136645.8
ENSMUST00000169913.8
INSC spindle orientation adaptor protein
chrX_+_149372903 0.26 ENSMUST00000080884.11
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_+_121786892 0.26 ENSMUST00000110578.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_150998857 0.26 ENSMUST00000105675.8
Parkinson disease (autosomal recessive, early onset) 7
chr5_-_66211842 0.25 ENSMUST00000200852.4
RNA binding motif protein 47
chr13_-_43634695 0.25 ENSMUST00000144326.4
RAN binding protein 9
chr11_-_117764258 0.25 ENSMUST00000033230.8
threonine aldolase 1
chr16_+_56024676 0.25 ENSMUST00000160116.8
ENSMUST00000069936.8
interphotoreceptor matrix proteoglycan 2
chr14_-_36820304 0.25 ENSMUST00000022337.11
cadherin-related family member 1
chr17_+_14087827 0.24 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr14_-_17305238 0.23 ENSMUST00000179659.2
predicted gene 3317
chr1_+_54289833 0.23 ENSMUST00000027128.11
coiled-coil domain containing 150
chr14_-_17955015 0.23 ENSMUST00000112776.4
predicted gene 3173
chr16_+_22965286 0.23 ENSMUST00000023593.6
adiponectin, C1Q and collagen domain containing
chr3_+_103482547 0.23 ENSMUST00000121834.8
synaptotagmin VI
chr5_-_143279378 0.23 ENSMUST00000212715.2
zinc finger protein 853
chr2_+_144112798 0.23 ENSMUST00000028910.9
ENSMUST00000110027.2
mitochondrial genome maintenance exonuclease 1
chr8_+_114362419 0.22 ENSMUST00000035777.10
MON1 homolog B, secretory traffciking associated
chr14_-_19619621 0.22 ENSMUST00000112595.3
predicted gene 2237
chr8_+_114362181 0.21 ENSMUST00000179926.9
MON1 homolog B, secretory traffciking associated
chr1_-_63215812 0.21 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr11_+_115197980 0.21 ENSMUST00000055490.9
otopetrin 2
chr1_-_144052997 0.21 ENSMUST00000111941.2
ENSMUST00000052375.8
regulator of G-protein signaling 13
chr13_+_67981349 0.20 ENSMUST00000222626.2
ENSMUST00000060609.8
predicted gene 10037
chr18_+_24737009 0.20 ENSMUST00000234266.2
ENSMUST00000025120.8
elongator acetyltransferase complex subunit 2
chr5_-_137015683 0.20 ENSMUST00000034953.14
ENSMUST00000085941.12
zinc finger, HIT domain containing 1
chr8_+_65399831 0.20 ENSMUST00000026595.13
ENSMUST00000209852.2
ENSMUST00000079896.9
transmembrane protein 192
chr11_+_69729340 0.19 ENSMUST00000133967.8
ENSMUST00000094065.5
transmembrane protein 256
chr11_+_116734104 0.19 ENSMUST00000106370.10
methyltransferase like 23
chr1_-_135211813 0.19 ENSMUST00000077340.14
ENSMUST00000074357.8
arginyl aminopeptidase (aminopeptidase B)
chr6_-_68968278 0.19 ENSMUST00000197966.2
immunoglobulin kappa variable 4-81
chr12_+_100076407 0.19 ENSMUST00000021595.10
protease (prosome, macropain) 26S subunit, ATPase 1
chr12_+_80691275 0.19 ENSMUST00000217889.2
solute carrier family 39 (zinc transporter), member 9
chrX_-_142716085 0.18 ENSMUST00000087313.10
doublecortin
chr16_-_19341016 0.18 ENSMUST00000214315.2
olfactory receptor 167
chr8_-_41494890 0.18 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr2_+_65676111 0.18 ENSMUST00000122912.8
cysteine-serine-rich nuclear protein 3
chr17_-_45970238 0.17 ENSMUST00000120717.8
calpain 11
chr10_-_83484467 0.16 ENSMUST00000146876.9
ENSMUST00000176294.2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr12_+_78240999 0.16 ENSMUST00000211288.3
predicted gene 6657
chr11_-_99907030 0.16 ENSMUST00000018399.3
keratin 33A
chr8_+_46463633 0.16 ENSMUST00000110381.9
Lrp2 binding protein
chr16_+_22965330 0.16 ENSMUST00000171309.2
adiponectin, C1Q and collagen domain containing
chr6_-_128599779 0.16 ENSMUST00000203275.3
killer cell lectin-like receptor subfamily B member 1A
chr7_+_126549692 0.16 ENSMUST00000106335.8
ENSMUST00000146017.3
seizure related 6 homolog like 2
chr3_+_55369149 0.15 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr1_-_131441962 0.15 ENSMUST00000185445.3
SLIT-ROBO Rho GTPase activating protein 2
chr5_-_90788460 0.15 ENSMUST00000202704.4
Ras association (RalGDS/AF-6) domain family member 6
chr6_+_41520737 0.15 ENSMUST00000103298.2
T cell receptor beta joining 2-7
chrX_+_159551009 0.14 ENSMUST00000033650.14
retinoschisis (X-linked, juvenile) 1 (human)
chr5_-_146521629 0.14 ENSMUST00000200112.2
ENSMUST00000197431.2
ENSMUST00000197825.2
G-protein coupled receptor 12
chr15_+_102927366 0.14 ENSMUST00000165375.3
homeobox C4
chr8_+_20478993 0.14 ENSMUST00000211848.2
predicted gene, 31371
chr10_-_129965752 0.14 ENSMUST00000215217.2
ENSMUST00000214192.2
olfactory receptor 824
chr6_-_90055488 0.14 ENSMUST00000203791.3
ENSMUST00000226368.2
vomeronasal 1, receptor 49
chr1_+_107350411 0.14 ENSMUST00000086690.6
serine (or cysteine) peptidase inhibitor, clade B, member 7
chr1_+_173924457 0.13 ENSMUST00000213832.2
olfactory receptor 427
chr14_+_53315909 0.12 ENSMUST00000103608.4
T cell receptor alpha variable 14D-3-DV8

Network of associatons between targets according to the STRING database.

First level regulatory network of Rhox4e_Rhox6_Vax2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.6 1.8 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.4 1.8 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.4 1.8 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 1.2 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.4 2.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.3 1.4 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.3 0.9 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.3 1.1 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269)
0.3 2.3 GO:0019532 oxalate transport(GO:0019532)
0.2 1.0 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 1.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 0.9 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.2 2.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 3.2 GO:0015747 urate transport(GO:0015747)
0.2 10.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 1.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.8 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 6.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 0.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0019085 early viral transcription(GO:0019085)
0.1 1.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.4 GO:0072249 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.1 0.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.8 GO:0006742 NADP catabolic process(GO:0006742)
0.1 0.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 6.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.6 GO:0033762 response to glucagon(GO:0033762)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0036471 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.6 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 5.2 GO:0007566 embryo implantation(GO:0007566)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.4 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 1.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 1.0 GO:0051923 sulfation(GO:0051923)
0.0 1.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.4 GO:0050955 thermoception(GO:0050955)
0.0 0.8 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 2.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.9 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 1.0 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.4 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.1 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0072144 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 4.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 1.0 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.0 3.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.0 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 1.1 GO:0097413 Lewy body(GO:0097413)
0.1 1.0 GO:0033503 HULC complex(GO:0033503)
0.1 1.4 GO:0000801 central element(GO:0000801)
0.1 2.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.9 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.3 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.1 1.0 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 4.7 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 5.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 4.1 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 10.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 1.8 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 0.9 GO:0070540 stearic acid binding(GO:0070540)
0.3 2.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.3 1.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 5.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.9 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.2 1.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 6.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 2.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.8 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 4.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 3.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.6 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.3 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 1.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.0 6.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 2.5 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 2.0 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 4.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport