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GSE58827: Dynamics of the Mouse Liver

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Results for Rorc_Nr1d1

Z-value: 0.53

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Transcription factors associated with Rorc_Nr1d1

Gene Symbol Gene ID Gene Info
Rorc
ENSMUSG00000028150.15 RAR-related orphan receptor gamma
Nr1d1
ENSMUSG00000020889.12 nuclear receptor subfamily 1, group D, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rorcmm39_v1_chr3_+_94284739_942847580.115.4e-01Click!
Nr1d1mm39_v1_chr11_-_98666159_98666183-0.048.3e-01Click!

Activity profile of Rorc_Nr1d1 motif

Sorted Z-values of Rorc_Nr1d1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_142215027 3.37 ENSMUST00000105936.8
Igf2
insulin-like growth factor 2
chr7_-_142215595 2.70 ENSMUST00000145896.3
Igf2
insulin-like growth factor 2
chr7_+_45354512 2.19 ENSMUST00000080885.12
ENSMUST00000211513.2
ENSMUST00000211357.2
Dbp
D site albumin promoter binding protein
chr1_-_120432669 2.16 ENSMUST00000027639.8
Marco
macrophage receptor with collagenous structure
chr5_+_90708962 1.86 ENSMUST00000094615.8
ENSMUST00000200765.2
Albfm1
albumin superfamily member 1
chr16_-_18904240 1.41 ENSMUST00000103746.3
Iglv1
immunoglobulin lambda variable 1
chr1_-_120432477 1.17 ENSMUST00000186432.3
Marco
macrophage receptor with collagenous structure
chr3_-_10273628 1.13 ENSMUST00000029041.6
Fabp4
fatty acid binding protein 4, adipocyte
chr17_+_43671314 1.11 ENSMUST00000226087.2
Adgrf5
adhesion G protein-coupled receptor F5
chr10_-_128237087 1.02 ENSMUST00000042666.13
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr14_+_79086492 0.96 ENSMUST00000040990.7
Vwa8
von Willebrand factor A domain containing 8
chr14_+_73379930 0.89 ENSMUST00000170370.8
ENSMUST00000164822.8
ENSMUST00000165429.8
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chrX_-_135104589 0.84 ENSMUST00000066819.11
Tceal5
transcription elongation factor A (SII)-like 5
chr17_+_25105617 0.82 ENSMUST00000117890.8
ENSMUST00000168265.8
ENSMUST00000120943.8
ENSMUST00000068508.13
ENSMUST00000119829.8
Spsb3
splA/ryanodine receptor domain and SOCS box containing 3
chr18_-_39000056 0.64 ENSMUST00000236630.2
ENSMUST00000237356.2
Fgf1
fibroblast growth factor 1
chr17_+_33857030 0.57 ENSMUST00000052079.8
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr13_+_6598185 0.56 ENSMUST00000021611.10
ENSMUST00000222485.2
Pitrm1
pitrilysin metallepetidase 1
chr11_+_4833186 0.55 ENSMUST00000139737.2
Nipsnap1
nipsnap homolog 1
chr7_-_105249308 0.54 ENSMUST00000210531.2
ENSMUST00000033185.10
Hpx
hemopexin
chr13_+_52750883 0.53 ENSMUST00000055087.7
Syk
spleen tyrosine kinase
chr4_+_115641996 0.49 ENSMUST00000177280.8
ENSMUST00000176047.8
Atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
chrX_-_135104386 0.46 ENSMUST00000151592.8
ENSMUST00000131510.2
Tceal5
transcription elongation factor A (SII)-like 5
chr11_+_114780867 0.46 ENSMUST00000106582.9
ENSMUST00000045151.6
Cd300a
CD300A molecule
chr5_+_31454787 0.45 ENSMUST00000201166.4
ENSMUST00000072228.9
Gckr
glucokinase regulatory protein
chr4_+_94627513 0.45 ENSMUST00000073939.13
ENSMUST00000102798.8
Tek
TEK receptor tyrosine kinase
chr3_+_108291145 0.44 ENSMUST00000090561.10
ENSMUST00000102629.8
ENSMUST00000128089.2
Psrc1
proline/serine-rich coiled-coil 1
chr2_+_90716204 0.44 ENSMUST00000111466.3
C1qtnf4
C1q and tumor necrosis factor related protein 4
chr8_+_3715747 0.43 ENSMUST00000014118.4
Mcemp1
mast cell expressed membrane protein 1
chr15_-_5137975 0.42 ENSMUST00000118365.3
Card6
caspase recruitment domain family, member 6
chr19_+_6434416 0.42 ENSMUST00000035269.15
ENSMUST00000113483.2
Pygm
muscle glycogen phosphorylase
chr10_+_25317309 0.41 ENSMUST00000217929.2
ENSMUST00000220121.2
Epb41l2
erythrocyte membrane protein band 4.1 like 2
chr6_+_29361408 0.40 ENSMUST00000156163.2
Calu
calumenin
chr3_+_90511068 0.38 ENSMUST00000001046.7
S100a4
S100 calcium binding protein A4
chr7_+_45276906 0.38 ENSMUST00000057927.10
Rasip1
Ras interacting protein 1
chr15_-_66673425 0.37 ENSMUST00000168589.8
Sla
src-like adaptor
chr7_+_126810780 0.36 ENSMUST00000032910.13
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_+_155593030 0.36 ENSMUST00000029140.12
ENSMUST00000132608.2
Procr
protein C receptor, endothelial
chr15_+_58287305 0.36 ENSMUST00000037270.5
Fam91a1
family with sequence similarity 91, member A1
chr17_-_46343291 0.35 ENSMUST00000071648.12
ENSMUST00000142351.9
Vegfa
vascular endothelial growth factor A
chr13_-_63036096 0.35 ENSMUST00000092888.11
Fbp1
fructose bisphosphatase 1
chr11_-_110058899 0.34 ENSMUST00000044850.4
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr8_-_95405234 0.34 ENSMUST00000213043.2
Pllp
plasma membrane proteolipid
chr15_-_5137951 0.34 ENSMUST00000141020.2
Card6
caspase recruitment domain family, member 6
chr7_+_114367971 0.33 ENSMUST00000117543.3
ENSMUST00000151464.2
Insc
INSC spindle orientation adaptor protein
chr17_-_46342739 0.33 ENSMUST00000024747.14
Vegfa
vascular endothelial growth factor A
chr9_-_30833748 0.31 ENSMUST00000065112.7
Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr12_-_84923252 0.31 ENSMUST00000163189.8
ENSMUST00000110254.9
ENSMUST00000002073.13
Ltbp2
latent transforming growth factor beta binding protein 2
chr6_-_88851027 0.29 ENSMUST00000038409.12
Podxl2
podocalyxin-like 2
chr14_-_60434622 0.29 ENSMUST00000131670.3
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr3_+_122305819 0.27 ENSMUST00000199344.2
Bcar3
breast cancer anti-estrogen resistance 3
chr7_-_133833734 0.27 ENSMUST00000134504.8
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr4_+_11558905 0.26 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
Rad54b
RAD54 homolog B (S. cerevisiae)
chr12_-_40298072 0.26 ENSMUST00000169926.8
Ifrd1
interferon-related developmental regulator 1
chr11_+_87471867 0.26 ENSMUST00000018544.12
ENSMUST00000063156.11
ENSMUST00000107960.8
Septin4
septin 4
chr3_+_53371086 0.25 ENSMUST00000058577.5
Proser1
proline and serine rich 1
chr3_-_53370621 0.25 ENSMUST00000056749.14
Nhlrc3
NHL repeat containing 3
chr11_+_101136821 0.24 ENSMUST00000129680.8
Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_-_79115760 0.24 ENSMUST00000125562.2
Polg
polymerase (DNA directed), gamma
chr12_+_3941728 0.24 ENSMUST00000172689.8
ENSMUST00000111186.8
Dnmt3a
DNA methyltransferase 3A
chr7_+_126895463 0.23 ENSMUST00000106306.9
ENSMUST00000120857.8
Itgal
integrin alpha L
chr7_-_79115915 0.22 ENSMUST00000073889.14
Polg
polymerase (DNA directed), gamma
chr5_+_135216090 0.22 ENSMUST00000002825.6
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr3_-_153650068 0.20 ENSMUST00000150070.2
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr7_-_99770280 0.19 ENSMUST00000208184.2
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_122917341 0.19 ENSMUST00000198257.5
ENSMUST00000199599.2
ENSMUST00000196742.2
ENSMUST00000200109.5
ENSMUST00000111668.8
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_-_92493507 0.19 ENSMUST00000194965.6
Smcp
sperm mitochondria-associated cysteine-rich protein
chr12_+_116011332 0.19 ENSMUST00000073551.6
ENSMUST00000183125.2
Zfp386
zinc finger protein 386 (Kruppel-like)
chr7_+_126895531 0.18 ENSMUST00000170971.8
Itgal
integrin alpha L
chr6_-_93890520 0.18 ENSMUST00000203688.3
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr19_+_31846154 0.18 ENSMUST00000224564.2
ENSMUST00000224304.2
ENSMUST00000075838.8
ENSMUST00000224400.2
A1cf
APOBEC1 complementation factor
chr10_+_80003612 0.17 ENSMUST00000105365.9
Cirbp
cold inducible RNA binding protein
chr15_-_10485976 0.17 ENSMUST00000169050.8
ENSMUST00000022855.12
Brix1
BRX1, biogenesis of ribosomes
chr7_-_30738471 0.17 ENSMUST00000162250.8
Fxyd5
FXYD domain-containing ion transport regulator 5
chr7_+_126895423 0.17 ENSMUST00000117762.8
Itgal
integrin alpha L
chr18_+_35987791 0.17 ENSMUST00000235404.2
Cxxc5
CXXC finger 5
chr14_-_36657517 0.16 ENSMUST00000183038.8
Ccser2
coiled-coil serine rich 2
chr14_-_40730180 0.16 ENSMUST00000136661.8
Prxl2a
peroxiredoxin like 2A
chr6_-_93890659 0.16 ENSMUST00000093769.8
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr5_-_65492940 0.16 ENSMUST00000203471.3
ENSMUST00000172732.8
ENSMUST00000204965.3
Rfc1
replication factor C (activator 1) 1
chr11_+_95603494 0.16 ENSMUST00000107717.8
Zfp652
zinc finger protein 652
chr2_+_153133326 0.15 ENSMUST00000028977.7
Kif3b
kinesin family member 3B
chr17_-_45997132 0.14 ENSMUST00000113523.9
Tmem63b
transmembrane protein 63b
chr2_+_48839505 0.14 ENSMUST00000112745.8
ENSMUST00000112754.8
Mbd5
methyl-CpG binding domain protein 5
chr5_-_5564873 0.14 ENSMUST00000060947.14
Cldn12
claudin 12
chr12_-_72455708 0.14 ENSMUST00000078505.14
Rtn1
reticulon 1
chr9_+_75348800 0.14 ENSMUST00000048937.6
Leo1
Leo1, Paf1/RNA polymerase II complex component
chr9_+_65368207 0.13 ENSMUST00000034955.8
ENSMUST00000213957.2
Spg21
SPG21, maspardin
chr4_-_116228921 0.13 ENSMUST00000239239.2
ENSMUST00000239177.2
Mast2
microtubule associated serine/threonine kinase 2
chr2_+_152596075 0.13 ENSMUST00000010020.12
Cox4i2
cytochrome c oxidase subunit 4I2
chr11_-_3599673 0.12 ENSMUST00000193809.2
Tug1
taurine upregulated gene 1
chr17_-_34847354 0.11 ENSMUST00000167097.9
Ppt2
palmitoyl-protein thioesterase 2
chr14_+_105496147 0.11 ENSMUST00000138283.2
Ndfip2
Nedd4 family interacting protein 2
chr13_+_104365432 0.11 ENSMUST00000070761.10
ENSMUST00000225557.2
Cenpk
centromere protein K
chr6_-_30873669 0.11 ENSMUST00000048774.13
ENSMUST00000166192.7
Copg2
coatomer protein complex, subunit gamma 2
chr17_-_34847013 0.10 ENSMUST00000166040.9
Ppt2
palmitoyl-protein thioesterase 2
chr15_+_10486092 0.09 ENSMUST00000022856.15
ENSMUST00000100775.10
ENSMUST00000169519.8
Rad1
RAD1 checkpoint DNA exonuclease
chr15_-_11996084 0.08 ENSMUST00000022816.15
Sub1
SUB1 homolog, transcriptional regulator
chr15_-_98560739 0.08 ENSMUST00000162384.2
ENSMUST00000003450.15
Ddx23
DEAD box helicase 23
chr19_-_43928583 0.08 ENSMUST00000212396.2
Dnmbp
dynamin binding protein
chr7_-_133833854 0.08 ENSMUST00000127524.2
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr3_-_103716593 0.08 ENSMUST00000063502.13
ENSMUST00000106832.2
ENSMUST00000106834.8
ENSMUST00000029435.15
Dclre1b
DNA cross-link repair 1B
chr11_+_58531220 0.08 ENSMUST00000075084.5
Trim58
tripartite motif-containing 58
chr11_+_116089678 0.08 ENSMUST00000021130.7
Ten1
TEN1 telomerase capping complex subunit
chr11_+_96822213 0.08 ENSMUST00000107633.2
Prr15l
proline rich 15-like
chr11_+_51989508 0.07 ENSMUST00000020608.3
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr3_+_79791798 0.06 ENSMUST00000118853.8
ENSMUST00000145992.2
Gask1b
golgi associated kinase 1B
chr14_-_55101505 0.06 ENSMUST00000142283.4
Homez
homeodomain leucine zipper-encoding gene
chr12_-_34578842 0.06 ENSMUST00000110819.4
Hdac9
histone deacetylase 9
chr7_-_99276310 0.05 ENSMUST00000178124.3
Tpbgl
trophoblast glycoprotein-like
chr16_-_20549294 0.05 ENSMUST00000231826.2
ENSMUST00000076422.13
ENSMUST00000232217.2
Thpo
thrombopoietin
chr6_-_124519240 0.05 ENSMUST00000159463.8
ENSMUST00000162844.2
ENSMUST00000160505.8
ENSMUST00000162443.8
C1s1
complement component 1, s subcomponent 1
chr5_+_145020910 0.05 ENSMUST00000124379.3
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr11_-_51526697 0.05 ENSMUST00000001081.10
Rmnd5b
required for meiotic nuclear division 5 homolog B
chr11_+_40624763 0.05 ENSMUST00000127382.2
Nudcd2
NudC domain containing 2
chr10_+_130158737 0.04 ENSMUST00000217702.2
ENSMUST00000042586.10
ENSMUST00000218605.2
Tespa1
thymocyte expressed, positive selection associated 1
chr7_-_126224848 0.04 ENSMUST00000032961.4
Nupr1
nuclear protein transcription regulator 1
chr5_+_145020640 0.04 ENSMUST00000031625.15
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr14_+_33775423 0.03 ENSMUST00000058725.5
Antxrl
anthrax toxin receptor-like
chr5_-_65492907 0.03 ENSMUST00000203581.3
Rfc1
replication factor C (activator 1) 1
chr1_+_86631510 0.02 ENSMUST00000168237.8
ENSMUST00000065694.8
Dis3l2
DIS3 like 3'-5' exoribonuclease 2
chr16_+_21828223 0.02 ENSMUST00000023561.8
Senp2
SUMO/sentrin specific peptidase 2
chrX_-_37665041 0.02 ENSMUST00000050083.6
ENSMUST00000115118.8
Cul4b
cullin 4B
chr14_+_53100756 0.02 ENSMUST00000103616.5
ENSMUST00000186370.2
Trav15d-1-dv6d-1
T cell receptor alpha variable 15D-1-DV6D-1
chr11_-_4045343 0.02 ENSMUST00000004868.6
Mtfp1
mitochondrial fission process 1
chr7_-_119461027 0.02 ENSMUST00000137888.2
ENSMUST00000142120.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr7_+_45683122 0.02 ENSMUST00000033121.7
Nomo1
nodal modulator 1
chr2_+_96148418 0.01 ENSMUST00000135431.8
ENSMUST00000162807.9
Lrrc4c
leucine rich repeat containing 4C
chr16_-_44379226 0.01 ENSMUST00000114634.3
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr2_-_152857239 0.01 ENSMUST00000028972.9
Pdrg1
p53 and DNA damage regulated 1
chr11_-_99176086 0.00 ENSMUST00000017255.4
Krt24
keratin 24
chr1_-_131161312 0.00 ENSMUST00000212202.2
Rassf5
Ras association (RalGDS/AF-6) domain family member 5
chr6_+_71176811 0.00 ENSMUST00000067492.8
Fabp1
fatty acid binding protein 1, liver

Network of associatons between targets according to the STRING database.

First level regulatory network of Rorc_Nr1d1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 0.7 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.2 1.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 0.5 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of eosinophil activation(GO:1902567) negative regulation of activation of JAK2 kinase activity(GO:1902569) negative regulation of eosinophil migration(GO:2000417)
0.1 0.5 GO:0071226 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
0.1 0.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 3.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 1.1 GO:0043031 negative regulation of macrophage activation(GO:0043031) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.1 0.5 GO:0060332 heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.5 GO:0009750 response to fructose(GO:0009750)
0.1 1.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.6 GO:1902563 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.1 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0061091 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.5 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.4 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 0.6 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 3.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 6.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 3.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 6.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein