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GSE58827: Dynamics of the Mouse Liver

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Results for Rxra

Z-value: 1.22

Motif logo

Transcription factors associated with Rxra

Gene Symbol Gene ID Gene Info
ENSMUSG00000015846.16 retinoid X receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxramm39_v1_chr2_+_27567213_275672410.591.7e-04Click!

Activity profile of Rxra motif

Sorted Z-values of Rxra motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39275518 28.65 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr19_+_20470056 16.30 ENSMUST00000225337.3
aldehyde dehydrogenase family 1, subfamily A1
chr7_+_26821266 15.08 ENSMUST00000206552.2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr3_+_138121245 13.47 ENSMUST00000161312.8
ENSMUST00000013458.9
alcohol dehydrogenase 4 (class II), pi polypeptide
chr19_+_20470114 13.19 ENSMUST00000225313.2
aldehyde dehydrogenase family 1, subfamily A1
chr2_+_172994841 11.12 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr11_-_116089866 10.53 ENSMUST00000066587.12
acyl-Coenzyme A oxidase 1, palmitoyl
chr15_+_82336535 10.53 ENSMUST00000089129.7
ENSMUST00000229313.2
ENSMUST00000231136.2
cytochrome P450, family 2, subfamily d, polypeptide 9
chr15_-_82264379 8.28 ENSMUST00000023083.9
cytochrome P450, family 2, subfamily d, polypeptide 22
chr6_-_85797946 8.09 ENSMUST00000032074.5
N-acetyltransferase 8 (GCN5-related) family member 5
chr11_-_78313043 7.72 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr13_-_24098981 7.15 ENSMUST00000110407.4
solute carrier family 17 (sodium phosphate), member 4
chr18_+_12732951 7.00 ENSMUST00000234255.2
ENSMUST00000169401.8
tetratricopeptide repeat domain 39C
chr13_-_24098951 6.60 ENSMUST00000021769.16
solute carrier family 17 (sodium phosphate), member 4
chr15_-_100579450 6.58 ENSMUST00000230740.2
chymotrypsin-like elastase family, member 1
chr11_-_116089595 6.53 ENSMUST00000072948.11
acyl-Coenzyme A oxidase 1, palmitoyl
chr12_-_103796632 6.37 ENSMUST00000164454.3
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr15_-_100579813 6.24 ENSMUST00000230572.2
chymotrypsin-like elastase family, member 1
chr1_+_74324089 5.84 ENSMUST00000113805.8
ENSMUST00000027370.13
ENSMUST00000087226.11
paroxysmal nonkinesiogenic dyskinesia
chr12_-_103706774 5.80 ENSMUST00000186166.7
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr1_-_180073492 5.78 ENSMUST00000010753.14
presenilin 2
chr9_-_103165489 5.68 ENSMUST00000035163.10
RIKEN cDNA 1300017J02 gene
chr9_-_103165423 5.59 ENSMUST00000123530.8
RIKEN cDNA 1300017J02 gene
chr17_-_74257164 4.68 ENSMUST00000024866.6
xanthine dehydrogenase
chr5_-_87402659 4.45 ENSMUST00000075858.4
UDP glucuronosyltransferase 2 family, polypeptide B37
chr2_+_155223728 4.42 ENSMUST00000043237.14
ENSMUST00000174685.8
transformation related protein 53 inducible nuclear protein 2
chr1_-_180073322 4.10 ENSMUST00000111104.2
presenilin 2
chr19_-_44017637 3.53 ENSMUST00000026211.10
ENSMUST00000211830.2
cytochrome P450, family 2, subfamily c, polypeptide 23
chr5_+_92719336 3.38 ENSMUST00000176621.8
ENSMUST00000175974.2
ENSMUST00000131166.9
ENSMUST00000176448.8
ENSMUST00000082382.8
family with sequence similarity 47, member E
chr2_-_121786573 3.35 ENSMUST00000104936.4
MAGE family member B3
chr19_-_6899121 3.29 ENSMUST00000173635.2
estrogen related receptor, alpha
chr9_-_103105638 3.23 ENSMUST00000126359.2
transferrin
chr4_-_103072343 3.18 ENSMUST00000150285.8
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr11_+_114566257 3.09 ENSMUST00000045779.6
tweety family member 2
chr19_+_36532061 2.98 ENSMUST00000169036.9
ENSMUST00000047247.12
HECT domain E3 ubiquitin protein ligase 2
chr19_-_6899173 2.93 ENSMUST00000025906.12
ENSMUST00000239322.2
estrogen related receptor, alpha
chr19_-_3962733 2.80 ENSMUST00000075092.8
ENSMUST00000235847.2
ENSMUST00000235301.2
ENSMUST00000237341.2
NADH:ubiquinone oxidoreductase core subunit S8
chr14_+_69409251 2.69 ENSMUST00000062437.10
NK2 homeobox 6
chr17_-_57024660 2.65 ENSMUST00000164907.3
ENSMUST00000233208.2
vimentin-type intermediate filament associated coiled-coil protein
chr6_+_133082202 2.58 ENSMUST00000191462.2
small integral membrane protein 10 like 1
chr6_+_78402956 2.57 ENSMUST00000079926.6
regenerating islet-derived 1
chr2_+_91033230 2.41 ENSMUST00000150403.8
ENSMUST00000002172.14
ENSMUST00000238832.2
ENSMUST00000239169.2
ENSMUST00000155418.2
acid phosphatase 2, lysosomal
chr16_+_4825216 2.25 ENSMUST00000185147.8
small integral membrane protein 22
chr10_-_7656635 2.02 ENSMUST00000124838.2
ENSMUST00000039763.14
glycoprotein integral membrane 1
chr9_+_65538352 2.01 ENSMUST00000216342.2
ENSMUST00000216382.2
RNA binding protein with multiple splicing 2
chr19_-_21449916 1.94 ENSMUST00000087600.10
guanine deaminase
chr2_-_69172944 1.89 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr10_+_77417554 1.87 ENSMUST00000009435.12
pituitary tumor-transforming 1 interacting protein
chr10_+_62897353 1.86 ENSMUST00000178684.3
ENSMUST00000020266.15
phenazine biosynthesis-like protein domain containing 1
chr10_+_77417608 1.85 ENSMUST00000162429.8
pituitary tumor-transforming 1 interacting protein
chr16_+_4825146 1.82 ENSMUST00000184439.8
small integral membrane protein 22
chr1_-_63215952 1.78 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr9_-_44876817 1.76 ENSMUST00000214761.2
ENSMUST00000213666.2
ENSMUST00000213890.2
ENSMUST00000125642.8
ENSMUST00000213193.2
ENSMUST00000117506.9
ENSMUST00000138559.9
ENSMUST00000117549.8
ubiquitination factor E4A
chr11_-_53313950 1.74 ENSMUST00000036045.6
liver-expressed antimicrobial peptide 2
chr17_+_57024759 1.72 ENSMUST00000002452.8
ENSMUST00000233832.2
ENSMUST00000233233.2
NADH:ubiquinone oxidoreductase subunit A11
chr19_+_5928649 1.67 ENSMUST00000136833.8
ENSMUST00000141362.2
solute carrier family 25, member 45
chr16_+_4825170 1.65 ENSMUST00000178155.9
small integral membrane protein 22
chr4_+_97665843 1.63 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chr11_+_50917831 1.57 ENSMUST00000072152.2
olfactory receptor 54
chr4_+_97665992 1.56 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr17_-_28039506 1.56 ENSMUST00000114859.9
ENSMUST00000233533.2
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr2_-_119060330 1.52 ENSMUST00000110820.3
protein phosphatase 1, regulatory inhibitor subunit 14D
chr14_+_122116002 1.52 ENSMUST00000039803.7
ubiquitin associated domain containing 2
chr9_+_44684248 1.49 ENSMUST00000128150.8
intraflagellar transport 46
chr6_+_73225616 1.47 ENSMUST00000203632.2
succinate-CoA ligase, GDP-forming, alpha subunit
chr8_-_71085097 1.47 ENSMUST00000110103.2
growth differentiation factor 15
chr17_-_15784582 1.46 ENSMUST00000147532.8
PR domain containing 9
chr6_-_85797917 1.38 ENSMUST00000174143.2
N-acetyltransferase 8 (GCN5-related) family member 6
chr4_+_126450762 1.38 ENSMUST00000147675.2
claspin
chr1_+_75456173 1.38 ENSMUST00000113575.9
ENSMUST00000148980.2
ENSMUST00000050899.7
ENSMUST00000187411.2
transmembrane protein 198
chr3_+_100732768 1.37 ENSMUST00000054791.9
V-set domain containing T cell activation inhibitor 1
chr14_+_12016304 1.35 ENSMUST00000161302.8
fragile histidine triad gene
chr10_+_77418221 1.34 ENSMUST00000162943.9
pituitary tumor-transforming 1 interacting protein
chr10_-_67384898 1.32 ENSMUST00000075686.7
2-aminoethanethiol (cysteamine) dioxygenase
chr9_+_44684206 1.29 ENSMUST00000002099.11
intraflagellar transport 46
chr12_-_79239022 1.27 ENSMUST00000161204.8
retinol dehydrogenase 11
chr6_+_41498716 1.27 ENSMUST00000070380.5
protease, serine 2
chr2_-_3420102 1.26 ENSMUST00000115082.10
meiosis expressed gene 1
chr8_-_100143029 1.26 ENSMUST00000155527.8
ENSMUST00000142129.8
ENSMUST00000093249.11
ENSMUST00000142475.3
ENSMUST00000128860.8
cadherin 8
chr9_+_44684285 1.25 ENSMUST00000239014.2
intraflagellar transport 46
chr1_-_63215812 1.22 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr7_-_98305986 1.19 ENSMUST00000205276.2
EMSY, BRCA2-interacting transcriptional repressor
chr9_+_108269992 1.19 ENSMUST00000192995.6
RIKEN cDNA 1700102P08 gene
chr2_-_3420056 1.17 ENSMUST00000115084.8
ENSMUST00000115083.8
meiosis expressed gene 1
chr19_+_10502679 1.14 ENSMUST00000235674.2
cleavage and polyadenylation specific factor 7
chr10_+_23836392 1.09 ENSMUST00000092660.2
trace amine-associated receptor 4
chr7_+_132460954 1.03 ENSMUST00000084497.12
ENSMUST00000106161.8
BRISC complex subunit
chr16_+_29028860 1.02 ENSMUST00000162747.8
phospholipase A and acyltransferase 1
chr17_-_28039588 0.98 ENSMUST00000114863.10
ENSMUST00000233131.2
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr6_+_8259328 0.98 ENSMUST00000159378.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr17_-_56933872 0.95 ENSMUST00000047226.10
lon peptidase 1, mitochondrial
chr7_+_23969822 0.95 ENSMUST00000108438.10
zinc finger protein 93
chr6_+_8259379 0.94 ENSMUST00000162034.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr5_+_14075281 0.94 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_-_172085977 0.93 ENSMUST00000111243.2
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr9_+_44684450 0.92 ENSMUST00000238800.2
ENSMUST00000147559.8
intraflagellar transport 46
chr6_+_8259405 0.92 ENSMUST00000160705.8
ENSMUST00000159433.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr7_-_29931612 0.91 ENSMUST00000006254.6
tubulin folding cofactor B
chr2_-_119060366 0.91 ENSMUST00000076084.6
protein phosphatase 1, regulatory inhibitor subunit 14D
chr14_+_54014387 0.90 ENSMUST00000103670.4
T cell receptor alpha variable 3-4
chr3_-_120965327 0.89 ENSMUST00000170781.2
ENSMUST00000039761.12
ENSMUST00000106467.8
ENSMUST00000106466.10
ENSMUST00000164925.9
RWD domain containing 3
chr10_-_79582387 0.88 ENSMUST00000020580.13
ENSMUST00000159016.8
polymerase (RNA) mitochondrial (DNA directed)
chr1_+_139429430 0.88 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr9_+_108270020 0.88 ENSMUST00000035234.6
RIKEN cDNA 1700102P08 gene
chr4_+_118286898 0.88 ENSMUST00000067896.4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr4_-_137301880 0.87 ENSMUST00000178923.2
low density lipoprotein receptor class A domain containing 2
chr17_-_36220518 0.87 ENSMUST00000141132.2
alpha tubulin acetyltransferase 1
chr4_+_118266582 0.87 ENSMUST00000144577.2
mediator complex subunit 8
chr7_+_43093507 0.85 ENSMUST00000004729.5
ENSMUST00000206286.2
ENSMUST00000206196.2
ENSMUST00000206411.2
electron transferring flavoprotein, beta polypeptide
chr9_+_44684324 0.83 ENSMUST00000214854.3
ENSMUST00000125877.8
intraflagellar transport 46
chr15_-_95426419 0.81 ENSMUST00000229933.2
ENSMUST00000166170.9
NEL-like 2
chr4_+_85123654 0.81 ENSMUST00000030212.15
ENSMUST00000107189.8
ENSMUST00000107184.8
SH3-domain GRB2-like 2
chr5_-_129916283 0.78 ENSMUST00000094280.4
coiled-coil-helix-coiled-coil-helix domain containing 2
chr2_+_164174660 0.78 ENSMUST00000017148.8
seminal vesicle secretory protein 5
chr7_-_28913382 0.77 ENSMUST00000169143.8
ENSMUST00000047846.13
cation channel sperm associated auxiliary subunit gamma 1
chr10_+_14581325 0.77 ENSMUST00000191238.7
ENSMUST00000190114.2
neuromedin B receptor
chr4_-_118266416 0.76 ENSMUST00000075406.12
SZT2 subunit of KICSTOR complex
chr10_+_74896383 0.76 ENSMUST00000164107.3
BCR activator of RhoGEF and GTPase
chr2_+_58991182 0.76 ENSMUST00000168631.8
ENSMUST00000102754.11
ENSMUST00000123908.8
plakophilin 4
chr17_-_36220924 0.74 ENSMUST00000141662.8
ENSMUST00000056034.13
ENSMUST00000077494.13
ENSMUST00000149277.8
ENSMUST00000061052.12
alpha tubulin acetyltransferase 1
chr7_-_98305737 0.74 ENSMUST00000205911.2
ENSMUST00000038359.6
ENSMUST00000206611.2
ENSMUST00000206619.2
EMSY, BRCA2-interacting transcriptional repressor
chrX_+_158197568 0.73 ENSMUST00000112471.9
MAP7 domain containing 2
chr15_-_97902576 0.72 ENSMUST00000023123.15
collagen, type II, alpha 1
chr8_+_12997948 0.72 ENSMUST00000110871.8
mcf.2 transforming sequence-like
chr3_+_27371206 0.72 ENSMUST00000174840.2
tumor necrosis factor (ligand) superfamily, member 10
chr13_+_113063988 0.71 ENSMUST00000038574.7
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chrX_-_147398149 0.71 ENSMUST00000112755.3
predicted gene 8334
chr10_+_78410180 0.69 ENSMUST00000218061.2
ENSMUST00000218787.2
ENSMUST00000105384.5
ENSMUST00000218875.2
ilvB (bacterial acetolactate synthase)-like
chr16_+_11140740 0.68 ENSMUST00000180792.8
sorting nexin 29
chr11_+_97689819 0.68 ENSMUST00000143571.2
LIM and SH3 protein 1
chr18_+_70605476 0.67 ENSMUST00000114959.9
StAR-related lipid transfer (START) domain containing 6
chr4_+_118266526 0.66 ENSMUST00000084319.11
ENSMUST00000106384.10
ENSMUST00000126089.8
ENSMUST00000073881.8
ENSMUST00000019229.15
mediator complex subunit 8
chr16_+_15135322 0.65 ENSMUST00000178312.2
predicted gene, 21897
chr3_+_27371168 0.65 ENSMUST00000046383.12
tumor necrosis factor (ligand) superfamily, member 10
chr11_-_11577824 0.64 ENSMUST00000081896.5
RIKEN cDNA 4930512M02 gene
chr12_-_74363168 0.64 ENSMUST00000110441.2
predicted gene 11042
chr2_-_32665596 0.63 ENSMUST00000161430.8
tetratricopeptide repeat domain 16
chr11_-_69906171 0.62 ENSMUST00000018718.8
ENSMUST00000102574.10
acyl-Coenzyme A dehydrogenase, very long chain
chr15_-_97902515 0.62 ENSMUST00000088355.12
collagen, type II, alpha 1
chr3_-_87965757 0.61 ENSMUST00000029708.8
NAD(P)HX epimerase
chr11_+_4570067 0.61 ENSMUST00000109941.2
predicted gene 11032
chr16_+_11140779 0.61 ENSMUST00000115814.4
sorting nexin 29
chr2_-_52225763 0.59 ENSMUST00000238288.2
ENSMUST00000238749.2
nebulin
chr14_-_14512458 0.59 ENSMUST00000211339.2
predicted gene 45521
chr2_-_26127360 0.59 ENSMUST00000036187.9
quiescin Q6 sulfhydryl oxidase 2
chr11_+_109376432 0.59 ENSMUST00000106697.8
arylsulfatase G
chr14_+_73898665 0.56 ENSMUST00000098874.4
predicted gene, 21750
chr3_-_153610528 0.56 ENSMUST00000190449.2
mutS homolog 4
chr7_+_141048191 0.55 ENSMUST00000211071.2
CD151 antigen
chr4_-_150087587 0.54 ENSMUST00000084117.13
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr19_-_12302465 0.54 ENSMUST00000207241.3
olfactory receptor 1437
chr7_-_29869126 0.54 ENSMUST00000062181.9
zinc finger protein 146
chr11_-_33463627 0.53 ENSMUST00000037522.14
RAN binding protein 17
chr3_-_153610368 0.53 ENSMUST00000188338.7
mutS homolog 4
chr5_-_24760401 0.52 ENSMUST00000088302.10
IQ motif containing with AAA domain 1 like
chr2_-_164041997 0.52 ENSMUST00000063251.3
WAP four-disulfide core domain 15A
chr14_+_53210216 0.50 ENSMUST00000103599.3
T cell receptor alpha variable 3D-3
chr5_+_31107390 0.50 ENSMUST00000006814.9
abhydrolase domain containing 1
chr14_+_53903370 0.48 ENSMUST00000181768.3
T cell receptor alpha variable 3-3
chr9_-_78285942 0.48 ENSMUST00000034900.8
oocyte expressed protein
chr2_-_32665637 0.47 ENSMUST00000161958.2
tetratricopeptide repeat domain 16
chr17_+_49922129 0.45 ENSMUST00000162854.2
kinesin family member 6
chr2_-_165210622 0.44 ENSMUST00000141140.2
ENSMUST00000103085.8
zinc finger protein 663
chr8_-_85741037 0.43 ENSMUST00000059072.6
ENSMUST00000209421.2
bestrophin 2
chr1_-_84912810 0.43 ENSMUST00000027422.7
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr17_-_57025022 0.43 ENSMUST00000233400.2
vimentin-type intermediate filament associated coiled-coil protein
chr9_+_45014092 0.43 ENSMUST00000217074.2
junction adhesion molecule like
chr5_-_115257336 0.42 ENSMUST00000031524.11
acyl-Coenzyme A dehydrogenase, short chain
chr7_-_43906629 0.41 ENSMUST00000012921.9
acid phosphatase 4
chr5_-_109704339 0.41 ENSMUST00000198960.2
cytokine receptor-like factor 2
chr1_+_165957909 0.41 ENSMUST00000166159.2
glycoprotein A33 (transmembrane)
chr8_-_4267459 0.40 ENSMUST00000176227.2
proline rich 36
chr11_+_5578738 0.40 ENSMUST00000137933.2
ankyrin repeat domain 36
chrX_+_6327790 0.40 ENSMUST00000143641.4
shroom family member 4
chr12_-_33142858 0.40 ENSMUST00000095774.3
cadherin-related family member 3
chrX_+_99537897 0.39 ENSMUST00000033570.6
immunoglobulin (CD79A) binding protein 1
chr5_-_73132045 0.39 ENSMUST00000043711.9
predicted gene 10135
chr1_-_57445576 0.38 ENSMUST00000160837.8
tRNA-yW synthesizing protein 5
chr4_+_118560720 0.37 ENSMUST00000214131.2
ENSMUST00000215117.3
olfactory receptor 1341
chr5_-_143831842 0.36 ENSMUST00000079624.12
ENSMUST00000110717.9
ankyrin repeat domain 61
chr1_-_74323795 0.35 ENSMUST00000178235.8
ENSMUST00000006462.14
angio-associated migratory protein
chrX_-_41000746 0.34 ENSMUST00000047037.15
THO complex 2
chr8_-_46452896 0.34 ENSMUST00000053558.10
ankyrin repeat domain 37
chr2_+_126057020 0.33 ENSMUST00000164042.3
predicted gene, 17555
chr2_+_164158651 0.33 ENSMUST00000017144.3
seminal vesicle secretory protein 6
chr6_+_21986445 0.33 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr2_+_157870653 0.32 ENSMUST00000152452.8
regulation of nuclear pre-mRNA domain containing 1B
chr2_-_21210151 0.32 ENSMUST00000027992.3
enkurin, TRPC channel interacting protein
chr9_-_20984790 0.32 ENSMUST00000010348.7
ferredoxin 2
chr17_-_35069136 0.32 ENSMUST00000046022.16
superkiller viralicidic activity 2-like (S. cerevisiae)
chr2_-_129541753 0.31 ENSMUST00000028883.12
prodynorphin
chr19_+_4008645 0.30 ENSMUST00000179433.8
aldehyde dehydrogenase 3 family, member B3
chr2_+_121786444 0.29 ENSMUST00000036647.13
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr7_-_4550523 0.29 ENSMUST00000206023.2
synaptotagmin V
chr11_-_106163753 0.28 ENSMUST00000021052.16
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr2_-_19558719 0.28 ENSMUST00000062060.5
RIKEN cDNA 4921504E06 gene
chr11_-_53509485 0.28 ENSMUST00000000889.7
interleukin 4
chr2_+_88644840 0.28 ENSMUST00000214703.2
olfactory receptor 1202
chr15_-_77330396 0.26 ENSMUST00000229434.2
apolipoprotein L 7b
chr13_+_33668761 0.26 ENSMUST00000081927.4
serine (or cysteine) peptidase inhibitor, clade B, member 9g

Network of associatons between targets according to the STRING database.

First level regulatory network of Rxra

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.1 GO:0018931 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
3.4 13.5 GO:0006069 ethanol oxidation(GO:0006069)
3.3 29.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
2.8 17.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
2.8 11.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
1.8 12.8 GO:0060309 elastin catabolic process(GO:0060309)
1.0 8.3 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.9 4.6 GO:0009115 xanthine catabolic process(GO:0009115)
0.9 28.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.7 2.7 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.6 1.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.6 9.9 GO:0043589 skin morphogenesis(GO:0043589)
0.6 5.8 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.5 1.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 1.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.5 1.9 GO:0046098 guanine metabolic process(GO:0046098)
0.4 3.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3 3.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 1.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 0.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.3 10.5 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.2 1.9 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 5.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 12.2 GO:0006953 acute-phase response(GO:0006953)
0.2 5.8 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 2.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 2.4 GO:0048102 autophagic cell death(GO:0048102)
0.2 3.2 GO:0072189 ureter development(GO:0072189)
0.2 1.4 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.1 1.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 7.9 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 1.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.4 GO:0072602 interleukin-4 secretion(GO:0072602)
0.1 0.4 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 1.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 2.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.4 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 6.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 1.0 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.5 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 4.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.3 GO:2000422 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1 13.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.1 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.9 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0031000 response to caffeine(GO:0031000)
0.1 0.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.4 GO:0035696 monocyte extravasation(GO:0035696)
0.1 1.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 8.6 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.8 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 1.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 4.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 3.0 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 1.3 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.4 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 1.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.0 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 3.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.6 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.4 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 2.5 GO:0035304 regulation of protein dephosphorylation(GO:0035304)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.9 GO:0035253 ciliary rootlet(GO:0035253)
0.3 3.2 GO:0097433 dense body(GO:0097433)
0.3 3.1 GO:0045098 type III intermediate filament(GO:0045098)
0.2 0.9 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 1.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.1 GO:0005713 recombination nodule(GO:0005713)
0.2 16.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 5.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 0.8 GO:1990130 Iml1 complex(GO:1990130)
0.1 7.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.6 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.0 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 1.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.6 GO:0042588 zymogen granule(GO:0042588)
0.1 0.8 GO:0036128 CatSper complex(GO:0036128)
0.0 3.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.4 GO:0005776 autophagosome(GO:0005776)
0.0 2.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 4.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:1904602 serotonin-activated cation-selective channel complex(GO:1904602)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 66.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 29.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
4.8 28.7 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
4.5 13.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
3.7 11.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.4 17.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.0 9.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.9 4.7 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.9 13.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.8 25.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.7 5.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.5 1.5 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.5 3.2 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 8.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391)
0.4 3.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.3 1.4 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.6 GO:0017099 long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 5.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 0.5 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.2 2.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 3.1 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 4.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 12.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 6.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 6.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 5.1 GO:0002039 p53 binding(GO:0002039)
0.0 2.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 6.9 GO:0005506 iron ion binding(GO:0005506)
0.0 8.2 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 3.0 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 4.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 9.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 15.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 43.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.7 17.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.6 9.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.5 9.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.5 6.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.5 7.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 3.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 8.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.3 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 6.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation