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GSE58827: Dynamics of the Mouse Liver

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Results for Scrt1

Z-value: 1.09

Motif logo

Transcription factors associated with Scrt1

Gene Symbol Gene ID Gene Info
ENSMUSG00000048385.10 scratch family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Scrt1mm39_v1_chr15_-_76406102_76406258-0.521.0e-03Click!

Activity profile of Scrt1 motif

Sorted Z-values of Scrt1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_30623592 14.10 ENSMUST00000217812.2
ENSMUST00000074671.9
hepcidin antimicrobial peptide 2
chr19_-_40062174 12.48 ENSMUST00000048959.5
cytochrome P450, family 2, subfamily c, polypeptide 54
chr10_-_127843377 9.25 ENSMUST00000219447.2
ENSMUST00000219780.2
ENSMUST00000219707.2
ENSMUST00000219953.2
ENSMUST00000219183.2
hydroxysteroid (17-beta) dehydrogenase 6
chr7_+_140343652 8.26 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr1_-_150341911 7.98 ENSMUST00000162367.8
ENSMUST00000161611.8
ENSMUST00000161320.8
ENSMUST00000159035.2
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr11_+_83637766 6.52 ENSMUST00000070832.3
WAP four-disulfide core domain 21
chr10_-_81127057 6.05 ENSMUST00000045744.7
tight junction protein 3
chr8_-_71990085 6.02 ENSMUST00000051672.9
bone marrow stromal cell antigen 2
chr7_-_30672747 5.83 ENSMUST00000205961.2
lipolysis stimulated lipoprotein receptor
chr7_-_30672824 5.57 ENSMUST00000147431.2
ENSMUST00000098553.11
ENSMUST00000108116.10
lipolysis stimulated lipoprotein receptor
chr10_-_81127334 5.50 ENSMUST00000219479.2
tight junction protein 3
chr6_+_138117519 5.48 ENSMUST00000120939.8
ENSMUST00000204628.3
ENSMUST00000140932.2
ENSMUST00000120302.8
microsomal glutathione S-transferase 1
chr7_-_30672889 5.45 ENSMUST00000001279.15
lipolysis stimulated lipoprotein receptor
chr6_+_138118565 5.21 ENSMUST00000118091.8
microsomal glutathione S-transferase 1
chr9_+_78164402 4.44 ENSMUST00000217203.2
predicted gene 3776
chr15_-_100576715 4.41 ENSMUST00000229869.2
chymotrypsin-like elastase family, member 1
chr7_-_105249308 4.27 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr13_-_53135064 3.94 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr12_-_103623418 3.91 ENSMUST00000044159.7
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr12_+_87193922 3.59 ENSMUST00000222885.2
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr18_+_56565188 3.34 ENSMUST00000070166.6
GRAM domain containing 3
chr10_-_106959444 3.33 ENSMUST00000165067.9
acyl-CoA synthetase short-chain family member 3
chr3_+_123061094 3.32 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr8_-_85620537 3.30 ENSMUST00000003907.14
ENSMUST00000109745.8
ENSMUST00000142748.2
glutaryl-Coenzyme A dehydrogenase
chr12_-_103871146 3.28 ENSMUST00000074051.6
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr4_-_57916283 3.24 ENSMUST00000063816.6
RIKEN cDNA D630039A03 gene
chr9_-_121745354 3.20 ENSMUST00000062474.5
cytochrome P450, family 8, subfamily b, polypeptide 1
chr11_-_59340739 3.13 ENSMUST00000136436.2
ENSMUST00000150297.2
ENSMUST00000010038.10
ENSMUST00000156146.8
ENSMUST00000132969.8
ENSMUST00000120940.8
synaptosomal-associated protein, 47
chr11_-_12414947 3.12 ENSMUST00000046755.14
ENSMUST00000109651.9
cordon-bleu WH2 repeat
chr15_-_96947963 3.07 ENSMUST00000230907.2
solute carrier family 38, member 4
chr17_-_56312555 2.78 ENSMUST00000043785.8
signal transducing adaptor family member 2
chr11_-_115078653 2.75 ENSMUST00000103041.8
N-acetyltransferase 9 (GCN5-related, putative)
chr10_+_75768964 2.73 ENSMUST00000219839.2
coiled-coil-helix-coiled-coil-helix domain containing 10
chr18_-_3281089 2.69 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr19_+_37425180 2.68 ENSMUST00000128184.3
hematopoietically expressed homeobox
chr10_+_116137277 2.66 ENSMUST00000092167.7
protein tyrosine phosphatase, receptor type, B
chr5_+_138170259 2.65 ENSMUST00000019662.11
ENSMUST00000151318.8
adaptor-related protein complex AP-4, mu 1
chr9_-_110709175 2.53 ENSMUST00000050958.9
transmembrane inner ear
chr17_+_56312672 2.49 ENSMUST00000133998.8
MPN domain containing
chr3_-_89009214 2.49 ENSMUST00000081848.13
farnesyl diphosphate synthetase
chr19_+_11514132 2.46 ENSMUST00000025581.7
membrane-spanning 4-domains, subfamily A, member 4D
chr3_-_89009153 2.46 ENSMUST00000199668.3
ENSMUST00000196709.5
farnesyl diphosphate synthetase
chr7_-_127545896 2.40 ENSMUST00000118755.8
ENSMUST00000094026.10
protease, serine 36
chr11_-_12414850 2.34 ENSMUST00000109650.8
cordon-bleu WH2 repeat
chr10_+_128158413 2.34 ENSMUST00000219836.2
canopy FGF signaling regulator 2
chr1_-_183150867 2.30 ENSMUST00000194543.4
melanoma inhibitory activity 3
chr12_-_103923145 2.29 ENSMUST00000085054.5
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr2_+_24866039 2.28 ENSMUST00000045295.14
patatin-like phospholipase domain containing 7
chr10_-_106959462 2.28 ENSMUST00000044668.5
acyl-CoA synthetase short-chain family member 3
chr6_-_23839136 2.21 ENSMUST00000166458.9
ENSMUST00000142913.9
ENSMUST00000069074.14
ENSMUST00000115361.9
ENSMUST00000018122.14
ENSMUST00000115356.3
Ca2+-dependent activator protein for secretion 2
chr15_-_77813123 2.20 ENSMUST00000109748.9
ENSMUST00000109747.9
ENSMUST00000100486.6
ENSMUST00000005487.12
thioredoxin 2
chr6_+_78402956 2.15 ENSMUST00000079926.6
regenerating islet-derived 1
chr5_+_137568113 2.14 ENSMUST00000031729.13
ENSMUST00000199054.5
transferrin receptor 2
chr8_+_77628916 2.14 ENSMUST00000109912.8
ENSMUST00000128862.2
ENSMUST00000109911.8
nuclear receptor subfamily 3, group C, member 2
chr5_+_137568086 2.12 ENSMUST00000198866.5
transferrin receptor 2
chr1_-_155912159 2.10 ENSMUST00000097527.10
torsin A interacting protein 1
chr5_-_33815760 2.09 ENSMUST00000019439.9
transmembrane protein 129
chr10_+_128158328 2.00 ENSMUST00000219037.2
ENSMUST00000026446.4
canopy FGF signaling regulator 2
chr12_-_86931529 1.97 ENSMUST00000038422.8
interferon regulatory factor 2 binding protein-like
chr7_-_133378410 1.97 ENSMUST00000130182.2
ENSMUST00000106139.8
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr18_-_3281727 1.88 ENSMUST00000154705.8
ENSMUST00000151084.8
cAMP responsive element modulator
chr1_+_131794962 1.87 ENSMUST00000112386.8
ENSMUST00000027693.8
RAB29, member RAS oncogene family
chr7_+_30673212 1.81 ENSMUST00000129773.2
family with sequence similarity 187, member B
chr2_+_153334710 1.81 ENSMUST00000109783.2
RIKEN cDNA 4930404H24 gene
chr7_-_88987917 1.78 ENSMUST00000137723.2
ENSMUST00000117852.8
ENSMUST00000041968.11
transmembrane protein 135
chr11_-_12414804 1.78 ENSMUST00000172919.8
cordon-bleu WH2 repeat
chr9_+_107765320 1.77 ENSMUST00000191906.6
ENSMUST00000035202.4
MON1 homolog A, secretory traffciking associated
chr16_+_3702604 1.76 ENSMUST00000115860.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr16_+_3702523 1.75 ENSMUST00000176625.8
ENSMUST00000186375.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr7_-_44318710 1.73 ENSMUST00000208131.2
myosin, heavy polypeptide 14
chr15_-_75886166 1.70 ENSMUST00000060807.12
family with sequence similarity 83, member H
chr16_+_16888084 1.68 ENSMUST00000231514.2
yippee like 1
chr16_+_16887991 1.64 ENSMUST00000232258.2
yippee like 1
chr8_-_106863423 1.63 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr4_-_129083251 1.60 ENSMUST00000117965.8
S100P binding protein
chr14_+_52122439 1.60 ENSMUST00000167984.2
methyltransferase like 17
chr17_-_56490887 1.58 ENSMUST00000019723.8
myeloid derived growth factor
chr7_-_44465998 1.56 ENSMUST00000209072.2
ENSMUST00000047356.11
activating transcription factor 5
chr7_-_133378468 1.56 ENSMUST00000033290.12
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr11_+_100960838 1.55 ENSMUST00000001802.10
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr16_+_36514386 1.54 ENSMUST00000119464.2
immunoglobulin-like domain containing receptor 1
chr19_+_24976864 1.53 ENSMUST00000025831.8
dedicator of cytokinesis 8
chr16_+_36514334 1.51 ENSMUST00000023617.13
ENSMUST00000089618.10
immunoglobulin-like domain containing receptor 1
chr6_-_148732893 1.50 ENSMUST00000145960.2
importin 8
chr7_-_133384449 1.49 ENSMUST00000063669.8
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chrX_+_5959507 1.49 ENSMUST00000103007.4
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr8_-_106863521 1.48 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr19_-_21630143 1.48 ENSMUST00000179768.8
ENSMUST00000178523.2
ENSMUST00000038830.10
RIKEN cDNA 1110059E24 gene
chr13_-_34837469 1.47 ENSMUST00000053459.15
PX domain containing 1
chr6_-_90693471 1.47 ENSMUST00000101153.10
IQ motif and Sec7 domain 1
chr1_-_156131155 1.44 ENSMUST00000141760.4
ENSMUST00000121146.10
tudor domain containing 5
chr16_+_16888145 1.42 ENSMUST00000232574.2
yippee like 1
chr7_+_99659121 1.39 ENSMUST00000107084.8
chordin-like 2
chr17_-_25300112 1.37 ENSMUST00000024984.7
transmembrane protein 204
chr16_-_4950285 1.37 ENSMUST00000035672.5
periplakin
chr10_-_102866076 1.36 ENSMUST00000218282.2
ENSMUST00000170026.2
ALX homeobox 1
predicted gene 17028
chr4_-_135221810 1.35 ENSMUST00000105856.9
NIPA-like domain containing 3
chr1_-_189075903 1.32 ENSMUST00000192723.2
ENSMUST00000110920.7
potassium channel, subfamily K, member 2
chr4_-_83242366 1.31 ENSMUST00000030205.14
ENSMUST00000048274.11
tetratricopeptide repeat domain 39B
chr6_-_41012435 1.30 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr18_-_3280999 1.29 ENSMUST00000049942.13
cAMP responsive element modulator
chr12_+_4642629 1.29 ENSMUST00000218402.2
intersectin 2
chr5_+_37403098 1.28 ENSMUST00000031004.11
collapsin response mediator protein 1
chr14_+_55120777 1.26 ENSMUST00000022806.10
BCL2-like 2
chr18_+_36693024 1.26 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr1_+_165288606 1.25 ENSMUST00000027853.6
mitochondrial pyruvate carrier 2
chr10_+_62935430 1.24 ENSMUST00000044059.5
atonal bHLH transcription factor 7
chr6_-_148732946 1.24 ENSMUST00000048418.14
importin 8
chr2_+_131075965 1.24 ENSMUST00000041362.12
ENSMUST00000110199.3
mitochondrial antiviral signaling protein
chr4_-_106474429 1.23 ENSMUST00000189032.7
ENSMUST00000106788.2
lymphocyte expansion molecule
chr17_-_26063488 1.23 ENSMUST00000176709.2
ras homolog family member T2
chr7_-_28981335 1.22 ENSMUST00000108236.5
ENSMUST00000098604.12
serine protease inhibitor, Kunitz type 2
chr19_-_21630078 1.20 ENSMUST00000177577.2
RIKEN cDNA 1110059E24 gene
chr17_+_24570991 1.17 ENSMUST00000039013.15
ATP-binding cassette, sub-family A (ABC1), member 3
chr11_+_53661251 1.17 ENSMUST00000138913.8
ENSMUST00000123376.8
ENSMUST00000019043.13
ENSMUST00000133291.3
interferon regulatory factor 1
chr1_+_172309337 1.16 ENSMUST00000127052.8
immunoglobulin superfamily, member 9
chr1_-_155912216 1.14 ENSMUST00000027738.14
torsin A interacting protein 1
chr16_-_3726503 1.14 ENSMUST00000115859.8
RIKEN cDNA 1700037C18 gene
chr9_+_81745723 1.14 ENSMUST00000057067.10
ENSMUST00000189832.7
ENSMUST00000189391.2
meiotic double-stranded break formation protein 4
chr15_-_100583044 1.13 ENSMUST00000230312.2
chymotrypsin-like elastase family, member 1
chr15_+_76555838 1.12 ENSMUST00000135388.3
protein phosphatase 1, regulatory subunit 16A
chr12_-_69771604 1.12 ENSMUST00000021370.10
L-2-hydroxyglutarate dehydrogenase
chr16_+_31482658 1.11 ENSMUST00000115201.8
discs large MAGUK scaffold protein 1
chr18_-_3281752 1.10 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr9_+_121245036 1.07 ENSMUST00000211187.2
trafficking protein, kinesin binding 1
chrX_+_69429475 1.07 ENSMUST00000053981.6
endothelium and lymphocyte associated ASCH domain 1
chr12_+_105302853 1.05 ENSMUST00000180458.9
Tcl1 upstream neural differentiation associated RNA
chr17_+_24571011 1.04 ENSMUST00000079594.12
ATP-binding cassette, sub-family A (ABC1), member 3
chr15_+_76555815 1.04 ENSMUST00000037551.15
protein phosphatase 1, regulatory subunit 16A
chr17_+_28491085 1.04 ENSMUST00000169040.3
peroxisome proliferator activator receptor delta
chr9_-_121686643 1.04 ENSMUST00000215007.2
ENSMUST00000216914.2
HIG1 domain family, member 1A
chrX_-_56549092 1.03 ENSMUST00000057645.6
G protein-coupled receptor 101
chr8_+_91635192 1.02 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr6_-_23839419 0.99 ENSMUST00000115358.9
ENSMUST00000163871.9
Ca2+-dependent activator protein for secretion 2
chr6_-_33037107 0.99 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr17_-_24752683 0.99 ENSMUST00000061764.14
RAB26, member RAS oncogene family
chr8_-_84874468 0.99 ENSMUST00000117424.9
ENSMUST00000040383.9
coiled-coil and C2 domain containing 1A
chr7_-_41042684 0.98 ENSMUST00000071804.10
ENSMUST00000206801.2
ENSMUST00000205338.2
expressed sequence AI987944
chr5_+_38434738 0.98 ENSMUST00000114099.6
otopetrin 1
chr16_-_10131804 0.96 ENSMUST00000078357.5
epithelial membrane protein 2
chr14_+_57661514 0.96 ENSMUST00000122063.8
intraflagellar transport 88
chr9_-_121686601 0.96 ENSMUST00000213124.2
ENSMUST00000215300.2
ENSMUST00000213147.2
HIG1 domain family, member 1A
chr4_+_95467653 0.95 ENSMUST00000043335.11
FGGY carbohydrate kinase domain containing
chr15_-_5137951 0.93 ENSMUST00000141020.2
caspase recruitment domain family, member 6
chr11_+_103540391 0.92 ENSMUST00000057870.4
reprimo-like
chrX_-_165262631 0.92 ENSMUST00000049435.15
RAB9, member RAS oncogene family
chr13_+_24118417 0.91 ENSMUST00000072391.2
H2A clustered histone 1
chr10_+_121477699 0.90 ENSMUST00000120642.9
ENSMUST00000132744.2
RIKEN cDNA D930020B18 gene
chr14_+_31750946 0.90 ENSMUST00000022460.11
polypeptide N-acetylgalactosaminyltransferase 15
chr4_+_40269563 0.90 ENSMUST00000129758.3
small integral membrane protein 27
chr18_-_7004717 0.87 ENSMUST00000079788.7
mohawk homeobox
chr14_+_28233301 0.87 ENSMUST00000112272.2
wingless-type MMTV integration site family, member 5A
chr3_+_80943667 0.85 ENSMUST00000029652.4
platelet-derived growth factor, C polypeptide
chr1_+_185187000 0.85 ENSMUST00000061093.7
solute carrier family 30, member 10
chr5_-_135807092 0.84 ENSMUST00000053906.11
ENSMUST00000177559.8
ENSMUST00000111161.9
ENSMUST00000111162.8
ENSMUST00000111163.9
serine/threonine/tyrosine interacting-like 1
chr15_-_5137975 0.84 ENSMUST00000118365.3
caspase recruitment domain family, member 6
chr7_-_118047394 0.84 ENSMUST00000203796.4
ENSMUST00000203485.3
synaptotagmin XVII
chr15_+_39609320 0.83 ENSMUST00000227368.2
ENSMUST00000228556.2
ENSMUST00000022913.6
ENSMUST00000228701.2
ENSMUST00000227792.2
dendrocyte expressed seven transmembrane protein
chr6_-_85742726 0.83 ENSMUST00000050780.8
N-acetyltransferase 8 (GCN5-related) family member 3
chr4_-_11386394 0.83 ENSMUST00000155519.2
epithelial splicing regulatory protein 1
chrX_-_151552457 0.83 ENSMUST00000101141.9
ENSMUST00000062317.5
shroom family member 2
chr9_+_110162470 0.82 ENSMUST00000198761.5
ENSMUST00000197630.3
SREBF chaperone
chr6_-_33037191 0.82 ENSMUST00000066379.11
coiled-coil-helix-coiled-coil-helix domain containing 3
chrX_-_71318353 0.81 ENSMUST00000064780.4
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr5_+_118307754 0.81 ENSMUST00000054836.7
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr2_+_164327988 0.80 ENSMUST00000109350.9
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_+_87704258 0.79 ENSMUST00000029711.9
ENSMUST00000107582.3
insulin receptor-related receptor
chr12_-_103623354 0.79 ENSMUST00000152517.2
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr14_+_61022006 0.78 ENSMUST00000063562.9
ENSMUST00000225043.2
mitochondrial intermediate peptidase
chr16_+_31482745 0.78 ENSMUST00000100001.10
ENSMUST00000064477.14
discs large MAGUK scaffold protein 1
chr17_+_34879431 0.77 ENSMUST00000238967.2
tenascin XB
chr5_-_30410720 0.77 ENSMUST00000088117.11
adhesion G protein-coupled receptor F3
chr9_+_110709301 0.77 ENSMUST00000123389.8
ALS2 C-terminal like
chr17_-_66258110 0.77 ENSMUST00000233580.2
ENSMUST00000024906.6
twisted gastrulation BMP signaling modulator 1
chr3_-_108747767 0.77 ENSMUST00000196679.5
syntaxin binding protein 3
chr17_-_25564501 0.77 ENSMUST00000153118.2
ENSMUST00000146856.3
tryptase alpha/beta 1
chr3_-_10400710 0.76 ENSMUST00000078748.4
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr5_-_33786919 0.75 ENSMUST00000153696.8
ENSMUST00000045329.10
ENSMUST00000065119.15
family with sequence similarity 53, member A
chr9_+_65122381 0.74 ENSMUST00000213396.2
poly (ADP-ribose) polymerase family, member 16
chr7_+_127440924 0.74 ENSMUST00000033075.14
syntaxin 4A (placental)
chr15_+_74828272 0.73 ENSMUST00000188042.2
lymphocyte antigen 6 complex, locus E
chr12_-_17374704 0.72 ENSMUST00000020884.16
ENSMUST00000095820.12
ENSMUST00000221129.2
ENSMUST00000127185.8
ATPase, H+ transporting, lysosomal V1 subunit C2
chr19_-_10857734 0.72 ENSMUST00000133303.8
transmembrane protein 109
chr6_+_107506678 0.71 ENSMUST00000049285.10
leucine rich repeat protein 1, neuronal
chrX_-_100865583 0.71 ENSMUST00000239206.2
predicted gene 3858
chr4_-_129083392 0.71 ENSMUST00000117497.8
ENSMUST00000117350.2
S100P binding protein
chr7_-_44465043 0.71 ENSMUST00000107893.9
activating transcription factor 5
chr17_-_26063391 0.71 ENSMUST00000176591.8
ras homolog family member T2
chr4_-_129083439 0.70 ENSMUST00000106059.8
S100P binding protein
chr9_+_110709223 0.69 ENSMUST00000084926.9
ALS2 C-terminal like
chr9_+_110709353 0.68 ENSMUST00000155014.2
ALS2 C-terminal like
chr5_-_114411851 0.67 ENSMUST00000044790.12
forkhead box N4
chr16_-_92262969 0.67 ENSMUST00000232239.2
ENSMUST00000060005.15
regulator of calcineurin 1
chr14_+_119375753 0.67 ENSMUST00000065904.5
heparan sulfate 6-O-sulfotransferase 3
chr8_+_4399588 0.66 ENSMUST00000110982.8
ENSMUST00000024004.9
chemokine (C-C motif) ligand 25
chr8_-_47986473 0.66 ENSMUST00000039061.15
trafficking protein particle complex 11
chr4_-_143677586 0.66 ENSMUST00000105766.2
PRAME like 16
chr9_+_110709260 0.65 ENSMUST00000130386.8
ALS2 C-terminal like
chr1_+_120268299 0.65 ENSMUST00000037286.12
complement component 1, q subcomponent-like 2
chr1_+_192856044 0.64 ENSMUST00000193307.2
RIKEN cDNA A130010J15 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Scrt1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
3.5 14.1 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
2.7 10.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
1.2 4.9 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
1.2 6.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
1.1 3.3 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
1.0 12.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
1.0 7.2 GO:0001757 somite specification(GO:0001757)
0.8 5.5 GO:0060309 elastin catabolic process(GO:0060309)
0.7 2.7 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.6 4.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.6 4.3 GO:0060335 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.6 5.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.5 1.4 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.5 1.9 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.4 1.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.4 1.3 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.4 1.2 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.4 1.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.4 3.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.4 3.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 3.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 4.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 2.7 GO:0061010 gall bladder development(GO:0061010)
0.4 1.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.4 1.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.3 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.3 5.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 3.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 3.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 0.9 GO:0060067 chemorepulsion of dopaminergic neuron axon(GO:0036518) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) melanocyte proliferation(GO:0097325) regulation of cell proliferation in midbrain(GO:1904933)
0.3 8.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.3 0.8 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.3 0.8 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.2 1.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.2 1.2 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 1.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 1.5 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.8 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.2 6.5 GO:0050872 white fat cell differentiation(GO:0050872)
0.2 0.6 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.3 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 2.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.2 0.9 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 1.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 4.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.2 2.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0042376 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 2.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 2.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.8 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 0.9 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.8 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 2.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.2 GO:0060129 corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 1.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.7 GO:0042407 cristae formation(GO:0042407)
0.1 7.4 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 3.3 GO:0032438 melanosome organization(GO:0032438)
0.1 0.4 GO:1990743 protein sialylation(GO:1990743)
0.1 0.3 GO:0071640 macrophage inflammatory protein-1 alpha production(GO:0071608) regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.1 0.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 1.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 3.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.5 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 1.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0060174 limb bud formation(GO:0060174)
0.1 1.3 GO:0022615 protein to membrane docking(GO:0022615)
0.1 1.8 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 0.3 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 2.0 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.1 2.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.2 GO:0021554 optic nerve development(GO:0021554)
0.1 1.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 1.0 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.7 GO:0048242 epinephrine secretion(GO:0048242)
0.1 0.2 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.1 1.0 GO:2001212 renal system process involved in regulation of blood volume(GO:0001977) regulation of glomerular filtration(GO:0003093) caveola assembly(GO:0070836) regulation of vasculogenesis(GO:2001212)
0.1 0.3 GO:0014028 notochord formation(GO:0014028)
0.1 1.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 2.8 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 1.0 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 2.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 6.8 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.8 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.4 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 1.4 GO:0031424 keratinization(GO:0031424)
0.0 1.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 1.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.4 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.0 GO:0035272 exocrine system development(GO:0035272)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901)
0.0 0.1 GO:0071043 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 1.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.8 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 5.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 7.2 GO:0008202 steroid metabolic process(GO:0008202)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 2.3 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 4.4 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.6 GO:0001964 startle response(GO:0001964)
0.0 0.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 2.2 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.2 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.0 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 19.9 GO:0061689 tricellular tight junction(GO:0061689)
0.8 7.2 GO:1990357 terminal web(GO:1990357)
0.7 2.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.4 4.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.7 GO:0097513 myosin II filament(GO:0097513)
0.2 1.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.8 GO:0061617 MICOS complex(GO:0061617)
0.2 1.3 GO:0044305 calyx of Held(GO:0044305)
0.2 3.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.3 GO:0070820 tertiary granule(GO:0070820)
0.2 0.7 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 3.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.0 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 1.4 GO:0071546 pi-body(GO:0071546)
0.1 11.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.9 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.5 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0042629 mast cell granule(GO:0042629)
0.1 2.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.5 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.7 GO:0045095 keratin filament(GO:0045095)
0.1 10.7 GO:0070160 occluding junction(GO:0070160)
0.0 9.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 6.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0044299 C-fiber(GO:0044299)
0.0 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 5.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 1.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 47.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 2.0 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 11.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 5.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 24.6 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.3 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.2 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
1.2 4.9 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.2 3.6 GO:0016034 maleylacetoacetate isomerase activity(GO:0016034)
1.2 9.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.1 5.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.9 4.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.8 3.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.8 2.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.7 2.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.7 4.3 GO:0015232 heme transporter activity(GO:0015232)
0.7 16.8 GO:0030228 low-density lipoprotein particle binding(GO:0030169) lipoprotein particle receptor activity(GO:0030228)
0.5 2.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 10.7 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3 1.0 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.3 1.0 GO:0019002 GMP binding(GO:0019002)
0.3 1.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.3 1.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 0.9 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 1.7 GO:1990254 keratin filament binding(GO:1990254)
0.3 6.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.9 GO:0097016 L27 domain binding(GO:0097016)
0.3 8.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 8.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 1.5 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 1.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 3.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 2.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.7 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 0.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 7.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 3.2 GO:0005521 lamin binding(GO:0005521)
0.1 1.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 14.1 GO:0005179 hormone activity(GO:0005179)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 2.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.4 GO:0047874 dolichyldiphosphatase activity(GO:0047874)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0004935 adrenergic receptor activity(GO:0004935)
0.1 11.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 5.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 3.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 3.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 6.5 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.3 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 2.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 1.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 2.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 9.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 10.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 3.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 3.5 GO:0000149 SNARE binding(GO:0000149)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 2.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 7.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 8.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 4.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 4.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 10.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 3.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 3.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 4.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 3.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 5.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events