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GSE58827: Dynamics of the Mouse Liver

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Results for Sox17

Z-value: 1.06

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Transcription factors associated with Sox17

Gene Symbol Gene ID Gene Info
Sox17
ENSMUSG00000025902.14 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox17mm39_v1_chr1_-_4566619_4566643-0.618.0e-05Click!

Activity profile of Sox17 motif

Sorted Z-values of Sox17 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_48516447 19.86 ENSMUST00000034808.12
ENSMUST00000119426.2
Nnmt
nicotinamide N-methyltransferase
chr8_-_93956143 9.08 ENSMUST00000176282.2
ENSMUST00000034173.14
Ces1e
carboxylesterase 1E
chr2_+_102489558 9.05 ENSMUST00000111213.8
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_+_22769822 8.66 ENSMUST00000023590.9
Hrg
histidine-rich glycoprotein
chr16_-_18232202 8.60 ENSMUST00000165430.8
ENSMUST00000147720.3
Comt
catechol-O-methyltransferase
chr16_+_22769844 8.10 ENSMUST00000232422.2
Hrg
histidine-rich glycoprotein
chr8_-_94063823 8.05 ENSMUST00000044602.8
Ces1g
carboxylesterase 1G
chr8_-_93924426 8.01 ENSMUST00000034172.8
Ces1d
carboxylesterase 1D
chr6_-_128503666 6.84 ENSMUST00000143664.2
ENSMUST00000112132.8
Pzp
PZP, alpha-2-macroglobulin like
chrX_+_59044796 6.39 ENSMUST00000033477.5
F9
coagulation factor IX
chr3_-_98670369 5.90 ENSMUST00000107019.8
ENSMUST00000107018.8
Hsd3b3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr8_+_107877252 5.65 ENSMUST00000034400.5
Cyb5b
cytochrome b5 type B
chr5_-_89605622 5.56 ENSMUST00000049209.13
Gc
vitamin D binding protein
chr7_-_100306160 5.24 ENSMUST00000107046.8
ENSMUST00000107045.9
ENSMUST00000139708.9
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr12_-_84447702 4.67 ENSMUST00000122194.8
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr5_-_104169696 4.46 ENSMUST00000119025.2
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr12_-_84447625 4.16 ENSMUST00000117286.2
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr1_-_162694076 4.12 ENSMUST00000046049.14
Fmo1
flavin containing monooxygenase 1
chr5_+_90708962 3.99 ENSMUST00000094615.8
ENSMUST00000200765.2
Albfm1
albumin superfamily member 1
chr4_-_42773987 3.97 ENSMUST00000095114.5
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr9_+_57428490 3.72 ENSMUST00000000090.8
Cox5a
cytochrome c oxidase subunit 5A
chr5_-_53370761 3.72 ENSMUST00000031090.8
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr6_+_121709891 3.05 ENSMUST00000204124.2
Gm7298
predicted gene 7298
chr11_-_59340739 2.64 ENSMUST00000136436.2
ENSMUST00000150297.2
ENSMUST00000010038.10
ENSMUST00000156146.8
ENSMUST00000132969.8
ENSMUST00000120940.8
Snap47
synaptosomal-associated protein, 47
chr8_-_41507808 2.59 ENSMUST00000093534.11
Mtus1
mitochondrial tumor suppressor 1
chr17_-_24428351 2.55 ENSMUST00000024931.6
Ntn3
netrin 3
chr7_+_28937859 2.44 ENSMUST00000108237.2
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr13_-_35211060 2.33 ENSMUST00000170538.8
ENSMUST00000163280.8
Eci2
enoyl-Coenzyme A delta isomerase 2
chr16_-_22847808 2.21 ENSMUST00000115349.9
Kng2
kininogen 2
chr5_-_38659449 2.20 ENSMUST00000005238.13
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr16_-_22847760 2.08 ENSMUST00000039338.13
Kng2
kininogen 2
chr11_-_109986763 2.05 ENSMUST00000046223.14
ENSMUST00000106664.10
ENSMUST00000106662.2
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr11_-_77784922 2.04 ENSMUST00000017597.5
Pipox
pipecolic acid oxidase
chr16_-_22847829 2.03 ENSMUST00000100046.9
Kng2
kininogen 2
chr11_-_109986804 1.97 ENSMUST00000100287.9
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr19_+_8897732 1.95 ENSMUST00000096243.7
B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_34560922 1.92 ENSMUST00000102825.4
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
chr7_-_127490139 1.89 ENSMUST00000205300.2
ENSMUST00000121394.3
Prss53
protease, serine 53
chr1_-_182169150 1.84 ENSMUST00000051431.10
Fbxo28
F-box protein 28
chr10_+_80084955 1.81 ENSMUST00000105364.8
Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
chr4_+_41903610 1.79 ENSMUST00000098128.4
Ccl21d
chemokine (C-C motif) ligand 21D
chr9_+_50405817 1.78 ENSMUST00000114474.8
ENSMUST00000188047.2
Plet1
placenta expressed transcript 1
chr4_+_42612121 1.75 ENSMUST00000178168.3
Gm10591
predicted gene 10591
chr4_+_42255693 1.68 ENSMUST00000178864.3
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr7_+_28937898 1.66 ENSMUST00000138128.3
ENSMUST00000142519.3
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr2_+_80447389 1.65 ENSMUST00000028384.5
Dusp19
dual specificity phosphatase 19
chr8_+_118428643 1.64 ENSMUST00000034304.9
Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_8288627 1.55 ENSMUST00000046470.16
ENSMUST00000150790.2
ENSMUST00000142899.2
Mettl22
methyltransferase like 22
chr16_+_22877000 1.55 ENSMUST00000039492.14
ENSMUST00000023589.15
ENSMUST00000089902.8
Kng1
kininogen 1
chr17_+_47747540 1.52 ENSMUST00000037701.13
AI661453
expressed sequence AI661453
chr17_+_47747657 1.52 ENSMUST00000150819.3
AI661453
expressed sequence AI661453
chr7_+_28937746 1.50 ENSMUST00000108238.8
ENSMUST00000032809.10
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_+_78488499 1.45 ENSMUST00000012331.7
Mogat1
monoacylglycerol O-acyltransferase 1
chr19_-_32717166 1.39 ENSMUST00000235142.2
ENSMUST00000070210.6
ENSMUST00000236011.2
Atad1
ATPase family, AAA domain containing 1
chrX_-_47966588 1.38 ENSMUST00000114928.2
Fsip2l
fibrous sheath-interacting protein 2-like
chr13_+_19374502 1.35 ENSMUST00000198330.2
ENSMUST00000103555.3
Trgv6
T cell receptor gamma, variable 6
chr19_-_32717138 1.34 ENSMUST00000236985.2
Atad1
ATPase family, AAA domain containing 1
chr9_+_108269992 1.34 ENSMUST00000192995.6
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr17_+_8529932 1.32 ENSMUST00000154553.2
ENSMUST00000140890.3
Sft2d1
Gm49987
SFT2 domain containing 1
predicted gene, 49987
chr11_-_68291638 1.29 ENSMUST00000108674.9
Ntn1
netrin 1
chr5_-_38659422 1.28 ENSMUST00000147664.8
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr16_-_22848153 1.26 ENSMUST00000232459.2
Kng2
kininogen 2
chr5_-_125466240 1.22 ENSMUST00000108707.3
Ubc
ubiquitin C
chr9_+_66853343 1.22 ENSMUST00000040917.14
ENSMUST00000127896.8
Rps27l
ribosomal protein S27-like
chr11_-_86698484 1.20 ENSMUST00000018569.14
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr2_+_52747855 1.18 ENSMUST00000155586.9
ENSMUST00000090952.11
ENSMUST00000127122.9
ENSMUST00000049483.14
ENSMUST00000050719.13
Fmnl2
formin-like 2
chr13_-_74642055 1.15 ENSMUST00000202645.4
ENSMUST00000221173.2
Zfp825
zinc finger protein 825
chr1_-_60605867 1.07 ENSMUST00000027168.12
ENSMUST00000090293.11
ENSMUST00000140485.8
Raph1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr9_+_3335507 1.06 ENSMUST00000212154.2
Alkbh8
alkB homolog 8, tRNA methyltransferase
chr2_-_57003064 1.04 ENSMUST00000112627.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr7_+_97049210 0.96 ENSMUST00000032882.9
ENSMUST00000149122.2
Ndufc2
NADH:ubiquinone oxidoreductase subunit C2
chr17_-_40553176 0.94 ENSMUST00000026499.6
Crisp3
cysteine-rich secretory protein 3
chr7_-_28329924 0.94 ENSMUST00000159095.2
ENSMUST00000159418.8
ENSMUST00000159560.3
Acp7
acid phosphatase 7, tartrate resistant
chr9_+_108270020 0.91 ENSMUST00000035234.6
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chrY_-_26732144 0.90 ENSMUST00000189518.2
Gm20890
predicted gene, 20890
chrY_-_27477265 0.90 ENSMUST00000188744.2
Gm21488
predicted gene, 21488
chr19_+_6356486 0.89 ENSMUST00000025681.8
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chrY_-_28226857 0.89 ENSMUST00000188864.2
Gm20894
predicted gene, 20894
chr18_+_80298441 0.86 ENSMUST00000123750.8
Slc66a2
solute carrier family 66 member 2
chr9_-_49338321 0.85 ENSMUST00000034792.7
Ankk1
ankyrin repeat and kinase domain containing 1
chr13_-_99584091 0.79 ENSMUST00000223725.2
Map1b
microtubule-associated protein 1B
chr1_+_171330978 0.78 ENSMUST00000081527.2
Alyref2
Aly/REF export factor 2
chr19_+_6234392 0.78 ENSMUST00000025699.9
ENSMUST00000113528.2
Majin
membrane anchored junction protein
chr12_-_40249314 0.72 ENSMUST00000095760.3
Lsmem1
leucine-rich single-pass membrane protein 1
chr7_-_28330322 0.67 ENSMUST00000040112.5
ENSMUST00000239470.2
Acp7
acid phosphatase 7, tartrate resistant
chr5_-_74863514 0.66 ENSMUST00000117388.8
Lnx1
ligand of numb-protein X 1
chr18_+_37440497 0.66 ENSMUST00000056712.4
Pcdhb4
protocadherin beta 4
chr6_-_112364974 0.62 ENSMUST00000238755.2
ENSMUST00000060847.6
Ssu2
ssu-2 homolog (C. elegans)
chr8_+_4298189 0.60 ENSMUST00000110993.2
Tgfbr3l
transforming growth factor, beta receptor III-like
chr6_-_144155197 0.59 ENSMUST00000038815.14
ENSMUST00000111749.8
ENSMUST00000170367.9
Sox5
SRY (sex determining region Y)-box 5
chr8_-_25215856 0.57 ENSMUST00000033958.15
Adam3
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr13_+_54225828 0.56 ENSMUST00000021930.10
Sfxn1
sideroflexin 1
chrX_+_73171069 0.54 ENSMUST00000033771.11
ENSMUST00000101457.10
Opn1mw
opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
chr14_+_54664359 0.53 ENSMUST00000010550.12
ENSMUST00000199195.3
ENSMUST00000196273.2
Mrpl52
mitochondrial ribosomal protein L52
chr9_+_110663656 0.53 ENSMUST00000011391.12
ENSMUST00000146794.4
Prss45
protease, serine 45
chr18_-_33346885 0.52 ENSMUST00000025236.9
Stard4
StAR-related lipid transfer (START) domain containing 4
chr10_+_77891161 0.50 ENSMUST00000131825.8
ENSMUST00000139539.8
ENSMUST00000123940.2
Dnmt3l
DNA (cytosine-5-)-methyltransferase 3-like
chr10_-_62198043 0.50 ENSMUST00000149534.2
Hk1
hexokinase 1
chr1_-_38875757 0.50 ENSMUST00000147695.9
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr2_-_76698725 0.48 ENSMUST00000149616.8
ENSMUST00000152185.8
ENSMUST00000130915.8
ENSMUST00000155365.8
ENSMUST00000128071.8
Ttn
titin
chr3_-_107240989 0.47 ENSMUST00000061772.11
Rbm15
RNA binding motif protein 15
chr10_-_128012336 0.45 ENSMUST00000092033.4
Rbms2
RNA binding motif, single stranded interacting protein 2
chr7_-_127897253 0.45 ENSMUST00000033044.16
Rusf1
RUS family member 1
chr6_-_144155167 0.45 ENSMUST00000077160.12
Sox5
SRY (sex determining region Y)-box 5
chr13_-_27852017 0.44 ENSMUST00000006660.7
Prl7a2
prolactin family 7, subfamily a, member 2
chr7_+_16693604 0.43 ENSMUST00000038163.8
Pnmal1
PNMA-like 1
chr5_-_107745404 0.40 ENSMUST00000124140.2
Glmn
glomulin, FKBP associated protein
chr10_-_23226684 0.39 ENSMUST00000220299.2
Eya4
EYA transcriptional coactivator and phosphatase 4
chr14_-_121935829 0.38 ENSMUST00000040700.9
ENSMUST00000212181.2
Dock9
dedicator of cytokinesis 9
chr5_+_27022355 0.38 ENSMUST00000071500.13
Dpp6
dipeptidylpeptidase 6
chr7_+_119927885 0.31 ENSMUST00000207220.2
ENSMUST00000121265.7
ENSMUST00000076272.5
Abca15
ATP-binding cassette, sub-family A (ABC1), member 15
chr17_+_48070100 0.30 ENSMUST00000125177.2
Tfeb
transcription factor EB
chr6_+_116466052 0.29 ENSMUST00000203700.3
Olfr211
olfactory receptor 211
chr2_-_121287174 0.27 ENSMUST00000110613.9
ENSMUST00000056312.10
Serinc4
serine incorporator 4
chr2_+_89804937 0.26 ENSMUST00000214630.2
ENSMUST00000111512.10
ENSMUST00000144710.3
ENSMUST00000216678.2
Olfr1260
olfactory receptor 1260
chr19_+_12394797 0.26 ENSMUST00000216506.2
ENSMUST00000214153.2
Olfr1441
olfactory receptor 1441
chr10_-_128904846 0.26 ENSMUST00000204515.3
Olfr766-ps1
olfactory receptor 766, pseudogene 1
chr11_-_97666701 0.25 ENSMUST00000107576.2
1700001P01Rik
RIKEN cDNA 1700001P01 gene
chr7_-_139785877 0.25 ENSMUST00000215815.2
Olfr524
olfactory receptor 524
chr7_+_103583554 0.23 ENSMUST00000214711.2
Olfr632
olfactory receptor 632
chr17_+_46739852 0.23 ENSMUST00000113465.10
ENSMUST00000024764.12
ENSMUST00000165993.2
Crip3
cysteine-rich protein 3
chr2_-_151528259 0.22 ENSMUST00000149319.2
Tmem74bos
transmembrane 74B, opposite strand
chr7_+_99384352 0.21 ENSMUST00000098264.2
Olfr520
olfactory receptor 520
chr10_-_102864921 0.21 ENSMUST00000217946.2
ENSMUST00000219194.2
Alx1
ALX homeobox 1
chr18_-_33346819 0.20 ENSMUST00000119991.8
ENSMUST00000118990.2
Stard4
StAR-related lipid transfer (START) domain containing 4
chr11_+_98537582 0.18 ENSMUST00000093938.10
ENSMUST00000017355.12
Gsdma2
gasdermin A2
chr8_-_25215778 0.18 ENSMUST00000171438.8
ENSMUST00000171611.9
Adam3
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr6_+_121222865 0.14 ENSMUST00000032198.11
Usp18
ubiquitin specific peptidase 18
chr8_+_106154266 0.13 ENSMUST00000067305.8
Lrrc36
leucine rich repeat containing 36
chr6_-_129761233 0.13 ENSMUST00000118532.8
Klrh1
killer cell lectin-like receptor subfamily H, member 1
chr4_+_118818775 0.13 ENSMUST00000058651.5
Lao1
L-amino acid oxidase 1
chr3_+_92259448 0.12 ENSMUST00000068399.2
Sprr2e
small proline-rich protein 2E
chr11_-_49005701 0.11 ENSMUST00000060398.3
ENSMUST00000215553.2
ENSMUST00000109201.2
Olfr1396
olfactory receptor 1396
chr9_-_35701371 0.11 ENSMUST00000034619.2
Pate6
prostate and testis expressed 6
chr13_+_33668761 0.10 ENSMUST00000081927.4
Serpinb9g
serine (or cysteine) peptidase inhibitor, clade B, member 9g
chr17_-_23783063 0.06 ENSMUST00000095606.5
Zfp213
zinc finger protein 213
chr5_+_138185747 0.06 ENSMUST00000110934.9
Cnpy4
canopy FGF signaling regulator 4
chr6_+_24857967 0.06 ENSMUST00000200968.4
Hyal5
hyaluronoglucosaminidase 5
chr6_+_68414401 0.05 ENSMUST00000103324.3
Igkv15-103
immunoglobulin kappa chain variable 15-103
chr3_-_87934772 0.04 ENSMUST00000005014.9
Hapln2
hyaluronan and proteoglycan link protein 2
chr9_-_75504926 0.04 ENSMUST00000164100.2
Tmod2
tropomodulin 2
chr14_+_68321302 0.04 ENSMUST00000022639.8
Nefl
neurofilament, light polypeptide
chr7_+_44984723 0.03 ENSMUST00000211327.2
Hrc
histidine rich calcium binding protein
chr3_+_132335575 0.03 ENSMUST00000212804.2
ENSMUST00000212852.2
Gimd1
GIMAP family P-loop NTPase domain containing 1
chr5_-_5713264 0.03 ENSMUST00000148193.2
Cfap69
cilia and flagella associated protein 69
chr15_-_97808502 0.01 ENSMUST00000173104.8
ENSMUST00000174633.8
Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
chr14_+_53220658 0.00 ENSMUST00000200548.2
Trav9d-4
T cell receptor alpha variable 9D-4
chr18_+_35731735 0.00 ENSMUST00000236868.2
Paip2
polyadenylate-binding protein-interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:0097037 heme export(GO:0097037)
2.7 8.1 GO:0034378 chylomicron assembly(GO:0034378) regulation of chylomicron remnant clearance(GO:0090320)
2.7 8.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
2.1 8.6 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
1.3 4.0 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
1.3 9.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.1 4.5 GO:0006710 androgen catabolic process(GO:0006710)
0.7 2.0 GO:0006553 lysine metabolic process(GO:0006553)
0.4 1.9 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.3 1.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.3 8.8 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.3 5.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.3 2.6 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 1.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 3.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 4.1 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 1.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 2.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 0.7 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 1.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 1.3 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 3.1 GO:0046415 urate metabolic process(GO:0046415)
0.1 9.1 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.5 GO:0043056 forward locomotion(GO:0043056)
0.1 0.8 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 1.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 6.8 GO:0007566 embryo implantation(GO:0007566)
0.1 0.3 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 2.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.5 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 2.8 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 1.8 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.0 7.6 GO:0031638 zymogen activation(GO:0031638)
0.0 20.2 GO:0032259 methylation(GO:0032259)
0.0 0.8 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.0 5.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 2.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 5.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 2.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.0 GO:0033693 neurofilament bundle assembly(GO:0033693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.8 GO:0061474 phagolysosome membrane(GO:0061474)
0.2 3.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 9.1 GO:0030673 axolemma(GO:0030673)
0.1 8.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 5.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 2.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 2.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 5.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 6.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 13.6 GO:0072562 blood microparticle(GO:0072562)
0.0 4.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 2.7 GO:0044439 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 6.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 6.1 GO:0043197 dendritic spine(GO:0043197)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.8 GO:0000800 lateral element(GO:0000800)
0.0 27.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 3.6 GO:0005743 mitochondrial inner membrane(GO:0005743)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
2.7 8.0 GO:0004771 sterol esterase activity(GO:0004771)
1.8 8.8 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
1.5 9.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.4 5.6 GO:1902271 D3 vitamins binding(GO:1902271)
0.8 5.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.5 1.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.5 6.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.5 2.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.5 9.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.4 4.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 6.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.3 2.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 1.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 1.4 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.2 25.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 3.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 19.9 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 5.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 3.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0008494 translation activator activity(GO:0008494)
0.1 2.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 8.0 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 5.7 GO:0020037 heme binding(GO:0020037)
0.0 8.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 4.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 30.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 28.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.2 3.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 6.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 18.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 9.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 6.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 4.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis