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GSE58827: Dynamics of the Mouse Liver
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Results for Sox2
Z-value: 3.56
Motif logo
Transcription factors associated with Sox2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Sox2
|
ENSMUSG00000074637.8 | SRY (sex determining region Y)-box 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox2 | mm39_v1_chr3_+_34704554_34704554 | 0.17 | 3.2e-01 | Click! |
Activity profile of Sox2 motif
Sorted Z-values of Sox2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of Sox2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 33.5 | 100.6 | GO:0034117 | erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118) |
| 13.7 | 41.2 | GO:0060217 | hemangioblast cell differentiation(GO:0060217) |
| 11.3 | 45.3 | GO:0032849 | positive regulation of cellular pH reduction(GO:0032849) dipeptide transmembrane transport(GO:0035442) regulation of oligopeptide transport(GO:0090088) regulation of dipeptide transport(GO:0090089) positive regulation of oligopeptide transport(GO:2000878) positive regulation of dipeptide transport(GO:2000880) regulation of dipeptide transmembrane transport(GO:2001148) positive regulation of dipeptide transmembrane transport(GO:2001150) |
| 8.7 | 26.1 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 6.2 | 18.7 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 5.5 | 16.4 | GO:1904024 | negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024) |
| 5.2 | 41.3 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 4.9 | 19.7 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 4.8 | 14.4 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 4.6 | 13.8 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 4.4 | 17.5 | GO:0051673 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 4.0 | 60.7 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
| 3.5 | 24.8 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 3.2 | 16.2 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
| 3.2 | 12.9 | GO:1990091 | sodium-dependent self proteolysis(GO:1990091) |
| 3.1 | 12.6 | GO:1904209 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 3.1 | 25.1 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 3.1 | 61.4 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 3.1 | 15.3 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 3.0 | 18.1 | GO:1903964 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 3.0 | 9.0 | GO:0042628 | mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297) seminal vesicle development(GO:0061107) |
| 3.0 | 3.0 | GO:1901003 | negative regulation of fermentation(GO:1901003) |
| 2.8 | 17.1 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 2.8 | 8.5 | GO:0019417 | sulfur oxidation(GO:0019417) |
| 2.8 | 22.2 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 2.7 | 24.6 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 2.7 | 16.2 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 2.7 | 31.9 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 2.6 | 7.8 | GO:0090673 | endothelial cell-matrix adhesion(GO:0090673) |
| 2.5 | 15.2 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 2.5 | 30.2 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 2.5 | 12.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 2.5 | 10.0 | GO:0003290 | atrial septum secundum morphogenesis(GO:0003290) |
| 2.4 | 24.0 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) |
| 2.4 | 14.3 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 2.3 | 9.3 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 2.2 | 11.1 | GO:0070543 | response to linoleic acid(GO:0070543) |
| 2.2 | 8.7 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 2.2 | 6.5 | GO:0033189 | response to vitamin A(GO:0033189) |
| 2.1 | 23.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 2.1 | 6.3 | GO:0015825 | L-serine transport(GO:0015825) |
| 2.1 | 8.3 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 2.0 | 14.3 | GO:0045716 | positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
| 2.0 | 8.1 | GO:0033377 | protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382) |
| 2.0 | 17.8 | GO:0030035 | microspike assembly(GO:0030035) |
| 1.9 | 7.6 | GO:0032752 | positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226) |
| 1.9 | 46.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 1.9 | 5.6 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 1.8 | 42.1 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 1.8 | 7.3 | GO:1904008 | response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009) |
| 1.8 | 12.6 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 1.8 | 7.1 | GO:0097477 | lateral motor column neuron migration(GO:0097477) |
| 1.7 | 3.4 | GO:0046984 | regulation of hemoglobin biosynthetic process(GO:0046984) |
| 1.7 | 10.0 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 1.6 | 4.9 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
| 1.6 | 1.6 | GO:0033122 | negative regulation of purine nucleotide catabolic process(GO:0033122) |
| 1.6 | 8.0 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 1.6 | 9.4 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 1.6 | 4.7 | GO:0002270 | plasmacytoid dendritic cell activation(GO:0002270) |
| 1.5 | 4.6 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 1.5 | 4.6 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 1.5 | 18.2 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 1.5 | 4.5 | GO:1990428 | miRNA transport(GO:1990428) |
| 1.5 | 4.4 | GO:0071846 | actin filament debranching(GO:0071846) |
| 1.5 | 1.5 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 1.4 | 4.3 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 1.4 | 5.8 | GO:1902896 | terminal web assembly(GO:1902896) |
| 1.4 | 8.5 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
| 1.4 | 4.2 | GO:1901074 | regulation of engulfment of apoptotic cell(GO:1901074) |
| 1.4 | 8.3 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 1.3 | 4.0 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
| 1.3 | 4.0 | GO:0046021 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 1.3 | 7.9 | GO:0010424 | DNA methylation on cytosine within a CG sequence(GO:0010424) |
| 1.3 | 6.6 | GO:1903898 | negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 1.3 | 5.2 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 1.3 | 5.1 | GO:0060221 | retinal rod cell differentiation(GO:0060221) |
| 1.2 | 17.5 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 1.2 | 3.7 | GO:0098749 | cerebellar neuron development(GO:0098749) |
| 1.2 | 26.0 | GO:0001675 | acrosome assembly(GO:0001675) |
| 1.2 | 3.7 | GO:0072720 | response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720) |
| 1.2 | 4.9 | GO:2001201 | regulation of transforming growth factor-beta secretion(GO:2001201) |
| 1.2 | 3.7 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 1.2 | 4.9 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 1.2 | 31.5 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 1.2 | 3.6 | GO:0045074 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) |
| 1.2 | 18.6 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 1.2 | 2.3 | GO:0060857 | establishment of glial blood-brain barrier(GO:0060857) |
| 1.2 | 26.6 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 1.2 | 33.5 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 1.1 | 8.0 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 1.1 | 1.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 1.1 | 4.6 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 1.1 | 6.8 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 1.1 | 11.3 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 1.1 | 6.8 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 1.1 | 7.9 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 1.1 | 29.0 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 1.1 | 4.5 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 1.1 | 6.6 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 1.1 | 6.6 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 1.1 | 8.7 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 1.1 | 5.4 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 1.1 | 7.5 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 1.1 | 6.5 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 1.0 | 29.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 1.0 | 16.1 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 1.0 | 9.0 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.9 | 6.5 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.9 | 0.9 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
| 0.9 | 6.5 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.9 | 2.8 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.9 | 1.8 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.9 | 9.2 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.9 | 2.7 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.9 | 5.4 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.9 | 2.7 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
| 0.9 | 2.7 | GO:0099552 | establishment of synaptic specificity at neuromuscular junction(GO:0007529) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
| 0.9 | 7.1 | GO:0060313 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.9 | 2.6 | GO:0072695 | negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695) |
| 0.9 | 4.4 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 0.9 | 2.6 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.9 | 2.6 | GO:0046832 | negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.8 | 6.7 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.8 | 11.0 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.8 | 12.6 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.8 | 3.3 | GO:0010609 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.8 | 4.9 | GO:0007412 | axon target recognition(GO:0007412) |
| 0.8 | 4.8 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
| 0.8 | 11.8 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.8 | 3.1 | GO:2000657 | regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657) |
| 0.8 | 3.1 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.8 | 7.8 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.8 | 3.0 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.7 | 9.6 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.7 | 2.9 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
| 0.7 | 5.1 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 0.7 | 8.7 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.7 | 10.1 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
| 0.7 | 2.8 | GO:0051586 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.7 | 3.5 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.7 | 2.6 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.7 | 2.6 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.6 | 2.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.6 | 1.9 | GO:2000328 | regulation of T-helper 17 cell lineage commitment(GO:2000328) |
| 0.6 | 4.3 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.6 | 4.2 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.6 | 5.3 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.6 | 2.3 | GO:0016584 | nucleosome positioning(GO:0016584) regulation of molecular function, epigenetic(GO:0040030) |
| 0.6 | 4.0 | GO:2000121 | regulation of removal of superoxide radicals(GO:2000121) |
| 0.6 | 4.0 | GO:0021888 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.6 | 3.4 | GO:2000327 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.6 | 7.3 | GO:0006527 | arginine catabolic process(GO:0006527) |
| 0.5 | 6.6 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
| 0.5 | 6.0 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.5 | 1.6 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642) |
| 0.5 | 1.6 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.5 | 3.7 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.5 | 2.6 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.5 | 12.6 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.5 | 1.0 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.5 | 1.5 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 0.5 | 2.5 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
| 0.5 | 10.8 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 0.5 | 9.2 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) |
| 0.5 | 1.4 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.5 | 8.1 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.5 | 3.8 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.5 | 4.7 | GO:0021546 | rhombomere development(GO:0021546) |
| 0.5 | 5.7 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.5 | 3.8 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.5 | 1.4 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.5 | 4.2 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.5 | 6.0 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.5 | 1.8 | GO:1902080 | regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081) |
| 0.5 | 3.7 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.5 | 4.1 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.5 | 4.1 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.4 | 3.1 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.4 | 2.7 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.4 | 3.1 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.4 | 6.7 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.4 | 4.3 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
| 0.4 | 9.3 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.4 | 12.3 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.4 | 1.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.4 | 10.0 | GO:0043486 | histone exchange(GO:0043486) |
| 0.4 | 16.3 | GO:0030220 | platelet formation(GO:0030220) |
| 0.4 | 1.2 | GO:0055130 | D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130) |
| 0.4 | 2.0 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.4 | 2.4 | GO:0036216 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.4 | 2.8 | GO:0043578 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.4 | 1.2 | GO:2001200 | positive regulation of dendritic cell differentiation(GO:2001200) |
| 0.4 | 6.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.4 | 4.3 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.4 | 1.6 | GO:0061187 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.4 | 3.1 | GO:0006689 | ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313) |
| 0.4 | 1.9 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.4 | 5.3 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
| 0.4 | 3.0 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.4 | 0.7 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) |
| 0.4 | 5.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.4 | 2.2 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
| 0.4 | 2.5 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.4 | 2.9 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.4 | 2.5 | GO:0099638 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
| 0.4 | 26.1 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.4 | 1.1 | GO:1903352 | mitochondrial ornithine transport(GO:0000066) histidine transport(GO:0015817) L-lysine transport(GO:1902022) L-ornithine transmembrane transport(GO:1903352) L-arginine transmembrane transport(GO:1903400) L-lysine transmembrane transport(GO:1903401) arginine transmembrane transport(GO:1903826) |
| 0.4 | 0.7 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.4 | 4.9 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.4 | 3.5 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.3 | 3.5 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.3 | 1.7 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.3 | 2.1 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.3 | 5.7 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.3 | 1.7 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 0.3 | 3.3 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.3 | 2.3 | GO:0040031 | snRNA modification(GO:0040031) |
| 0.3 | 7.2 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.3 | 1.3 | GO:0003162 | atrioventricular node development(GO:0003162) |
| 0.3 | 2.3 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.3 | 1.9 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.3 | 3.9 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.3 | 1.3 | GO:0018201 | peptidyl-glycine modification(GO:0018201) |
| 0.3 | 1.6 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.3 | 2.2 | GO:0070875 | positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875) |
| 0.3 | 4.7 | GO:0046036 | CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.3 | 1.5 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.3 | 1.2 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.3 | 1.8 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.3 | 0.6 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
| 0.3 | 3.0 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.3 | 29.8 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.3 | 1.5 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.3 | 3.6 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.3 | 1.5 | GO:0034164 | negative regulation of toll-like receptor 9 signaling pathway(GO:0034164) |
| 0.3 | 7.4 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.3 | 7.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.3 | 1.5 | GO:0030576 | Cajal body organization(GO:0030576) |
| 0.3 | 3.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.3 | 1.1 | GO:2000397 | positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 0.3 | 5.1 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.3 | 2.8 | GO:0001781 | neutrophil apoptotic process(GO:0001781) |
| 0.3 | 7.5 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.3 | 1.9 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.3 | 1.1 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.3 | 12.9 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.3 | 0.3 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.3 | 4.4 | GO:0030049 | muscle filament sliding(GO:0030049) |
| 0.3 | 3.6 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.3 | 1.0 | GO:0070858 | negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252) |
| 0.3 | 1.0 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) |
| 0.3 | 1.0 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.3 | 5.0 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.3 | 1.5 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.2 | 12.1 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.2 | 1.5 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.2 | 1.0 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.2 | 5.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.2 | 0.9 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
| 0.2 | 3.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.2 | 0.9 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.2 | 7.8 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
| 0.2 | 0.7 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.2 | 3.1 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.2 | 20.8 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.2 | 3.0 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.2 | 4.3 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
| 0.2 | 1.1 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.2 | 0.8 | GO:0042494 | detection of bacterial lipoprotein(GO:0042494) |
| 0.2 | 1.3 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.2 | 1.9 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.2 | 4.4 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.2 | 2.3 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
| 0.2 | 3.9 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.2 | 5.1 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.2 | 2.6 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.2 | 3.7 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.2 | 1.2 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.2 | 3.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.2 | 0.6 | GO:0060353 | regulation of cell adhesion molecule production(GO:0060353) |
| 0.2 | 6.9 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.2 | 8.4 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 12.6 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.2 | 4.7 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.2 | 0.8 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
| 0.2 | 0.8 | GO:0001711 | endodermal cell fate commitment(GO:0001711) |
| 0.2 | 3.2 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.2 | 3.0 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.2 | 3.2 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
| 0.2 | 1.7 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
| 0.2 | 2.6 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.2 | 4.2 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.2 | 4.9 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.2 | 1.4 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.2 | 4.3 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.2 | 1.2 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 0.9 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 0.2 | 1.7 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 1.7 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.2 | 2.1 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.2 | 1.9 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.2 | 25.3 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.2 | 1.6 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.2 | 4.4 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.2 | 1.2 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
| 0.2 | 1.1 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
| 0.2 | 4.9 | GO:0014823 | response to activity(GO:0014823) |
| 0.2 | 0.9 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.2 | 11.9 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 2.8 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 14.0 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.1 | 2.4 | GO:0006855 | drug transmembrane transport(GO:0006855) |
| 0.1 | 0.4 | GO:0030887 | positive regulation of myeloid dendritic cell activation(GO:0030887) |
| 0.1 | 3.2 | GO:0050860 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 0.9 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
| 0.1 | 4.2 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 3.8 | GO:1903427 | negative regulation of reactive oxygen species biosynthetic process(GO:1903427) |
| 0.1 | 2.2 | GO:0043306 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
| 0.1 | 1.7 | GO:1990035 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.1 | 0.8 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.1 | 1.3 | GO:0090190 | regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.1 | 3.5 | GO:0021535 | cell migration in hindbrain(GO:0021535) |
| 0.1 | 1.2 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.1 | 0.4 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.1 | 2.0 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.3 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
| 0.1 | 4.4 | GO:0008203 | cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652) |
| 0.1 | 1.2 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.1 | 2.5 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.1 | 8.4 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.1 | 0.9 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 1.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.1 | 2.9 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.1 | 2.1 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.1 | 3.0 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.1 | 0.9 | GO:0060017 | parathyroid gland development(GO:0060017) |
| 0.1 | 3.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 1.9 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.1 | 4.6 | GO:1901099 | negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
| 0.1 | 1.3 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 1.9 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.1 | 3.9 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
| 0.1 | 6.8 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
| 0.1 | 0.3 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 3.5 | GO:2000401 | regulation of lymphocyte migration(GO:2000401) |
| 0.1 | 3.2 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.5 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 1.2 | GO:0016073 | snRNA transcription(GO:0009301) snRNA metabolic process(GO:0016073) |
| 0.1 | 1.7 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.1 | 1.5 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 1.2 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.1 | 0.5 | GO:0098957 | anterograde axonal transport of mitochondrion(GO:0098957) |
| 0.1 | 8.0 | GO:0030168 | platelet activation(GO:0030168) |
| 0.1 | 0.3 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.1 | 9.5 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.1 | 4.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.4 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.1 | 0.4 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 1.0 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.1 | 3.3 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 2.9 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
| 0.1 | 1.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.1 | 1.7 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.1 | 0.5 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.1 | 0.6 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.1 | 7.9 | GO:0007127 | meiosis I(GO:0007127) |
| 0.1 | 0.3 | GO:1902808 | positive regulation of cell cycle G1/S phase transition(GO:1902808) |
| 0.1 | 0.8 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 0.2 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.1 | 1.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 1.4 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.1 | 0.7 | GO:0043247 | telomere maintenance in response to DNA damage(GO:0043247) |
| 0.1 | 0.3 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.1 | 0.4 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.1 | 1.1 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.1 | 0.4 | GO:1900084 | regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.1 | 0.5 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.1 | 0.5 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 1.5 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.1 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.1 | 3.0 | GO:0032204 | regulation of telomere maintenance(GO:0032204) |
| 0.1 | 0.4 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.1 | 2.5 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 0.1 | 1.7 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 2.7 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 1.3 | GO:0001967 | suckling behavior(GO:0001967) |
| 0.1 | 0.2 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.5 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.1 | 11.7 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 0.1 | 7.0 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.1 | 3.8 | GO:0032092 | positive regulation of protein binding(GO:0032092) |
| 0.1 | 3.5 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 1.1 | GO:2000036 | regulation of stem cell population maintenance(GO:2000036) |
| 0.1 | 4.3 | GO:0007586 | digestion(GO:0007586) |
| 0.1 | 1.9 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.1 | 0.6 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.0 | 0.4 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.0 | 0.3 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.0 | 0.3 | GO:0046479 | glycosphingolipid catabolic process(GO:0046479) |
| 0.0 | 1.3 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.1 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 0.0 | 0.3 | GO:0070893 | transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895) |
| 0.0 | 2.2 | GO:0019319 | hexose biosynthetic process(GO:0019319) |
| 0.0 | 0.2 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.0 | 0.9 | GO:1990089 | response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.0 | 0.4 | GO:0046851 | negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851) |
| 0.0 | 0.3 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.0 | 0.3 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 2.4 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 1.1 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.0 | 0.4 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.4 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) |
| 0.0 | 5.2 | GO:1903169 | regulation of calcium ion transmembrane transport(GO:1903169) |
| 0.0 | 2.4 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 0.3 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 0.2 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.4 | GO:0046549 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.0 | 0.5 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.0 | 4.6 | GO:0006694 | steroid biosynthetic process(GO:0006694) |
| 0.0 | 4.2 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 1.5 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.2 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 0.0 | 0.6 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.0 | 1.0 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 0.8 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.4 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.0 | 0.3 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.1 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.2 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 1.5 | GO:0006096 | glycolytic process(GO:0006096) |
| 0.0 | 0.0 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.0 | 0.2 | GO:0007527 | adult somatic muscle development(GO:0007527) |
| 0.0 | 0.2 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.4 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.2 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.0 | 0.0 | GO:2000744 | anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
| 0.0 | 1.0 | GO:0051057 | positive regulation of small GTPase mediated signal transduction(GO:0051057) |
| 0.0 | 0.1 | GO:0050854 | regulation of antigen receptor-mediated signaling pathway(GO:0050854) regulation of T cell receptor signaling pathway(GO:0050856) |
| 0.0 | 0.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.3 | GO:0042246 | tissue regeneration(GO:0042246) |
| 0.0 | 0.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.2 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
| 0.0 | 0.3 | GO:0035094 | response to nicotine(GO:0035094) |
| 0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 0.3 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.1 | GO:0043981 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 4.2 | GO:0008380 | RNA splicing(GO:0008380) |
| 0.0 | 1.1 | GO:2000045 | regulation of G1/S transition of mitotic cell cycle(GO:2000045) |
| 0.0 | 0.4 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.0 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.0 | 0.0 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 13.7 | 41.2 | GO:0033193 | Lsd1/2 complex(GO:0033193) |
| 7.7 | 31.0 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 7.2 | 43.1 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 4.9 | 29.7 | GO:0042585 | germinal vesicle(GO:0042585) |
| 4.7 | 18.7 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 4.4 | 17.8 | GO:0008623 | CHRAC(GO:0008623) |
| 4.4 | 48.3 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 3.9 | 15.7 | GO:0001740 | Barr body(GO:0001740) |
| 3.7 | 100.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 3.6 | 10.9 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 3.2 | 3.2 | GO:0035101 | FACT complex(GO:0035101) |
| 3.1 | 15.3 | GO:0071914 | prominosome(GO:0071914) |
| 2.9 | 17.5 | GO:0044218 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 2.8 | 17.1 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 2.8 | 14.2 | GO:0044393 | microspike(GO:0044393) |
| 2.8 | 8.5 | GO:0031904 | endosome lumen(GO:0031904) |
| 2.3 | 16.2 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 1.9 | 30.7 | GO:0042555 | MCM complex(GO:0042555) |
| 1.9 | 9.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 1.9 | 39.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 1.8 | 10.9 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 1.8 | 8.9 | GO:0071953 | elastic fiber(GO:0071953) |
| 1.8 | 12.4 | GO:0098645 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 1.7 | 17.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 1.7 | 30.9 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 1.7 | 28.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 1.6 | 6.3 | GO:0031094 | platelet dense tubular network(GO:0031094) |
| 1.5 | 4.6 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 1.5 | 10.8 | GO:0005638 | lamin filament(GO:0005638) |
| 1.5 | 19.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 1.5 | 9.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 1.5 | 4.4 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 1.4 | 8.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 1.4 | 8.1 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 1.2 | 9.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.2 | 19.2 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.2 | 3.5 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 1.1 | 9.0 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.1 | 5.5 | GO:0061673 | mitotic spindle astral microtubule(GO:0061673) |
| 1.1 | 7.6 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 1.1 | 5.4 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 1.0 | 6.8 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.9 | 7.8 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.8 | 6.7 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.8 | 7.8 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.8 | 9.0 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.7 | 6.7 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.7 | 8.1 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.7 | 3.7 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.7 | 5.3 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.6 | 3.2 | GO:0031251 | PAN complex(GO:0031251) |
| 0.6 | 6.4 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.6 | 16.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.6 | 3.1 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.6 | 1.8 | GO:0070877 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.6 | 9.2 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.6 | 2.4 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.6 | 13.6 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.6 | 10.5 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.6 | 6.4 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.5 | 7.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.5 | 38.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.5 | 6.9 | GO:0034709 | methylosome(GO:0034709) |
| 0.5 | 25.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.5 | 2.6 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.5 | 7.8 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.5 | 5.7 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.5 | 3.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.5 | 5.5 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.5 | 3.9 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.5 | 4.8 | GO:0002177 | manchette(GO:0002177) |
| 0.5 | 4.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.5 | 4.2 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 0.5 | 4.6 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.5 | 3.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.4 | 6.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.4 | 1.3 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.4 | 1.2 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.4 | 2.8 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.4 | 1.6 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.4 | 5.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.4 | 3.5 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.4 | 51.3 | GO:0005902 | microvillus(GO:0005902) |
| 0.4 | 30.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.4 | 2.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.4 | 3.2 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.4 | 3.5 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.4 | 3.5 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.3 | 58.1 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.3 | 2.8 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.3 | 31.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.3 | 2.8 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.3 | 2.8 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.3 | 7.6 | GO:0032982 | myosin filament(GO:0032982) |
| 0.3 | 1.2 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.3 | 18.1 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.3 | 5.6 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.3 | 1.7 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.3 | 21.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.3 | 1.9 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.3 | 3.0 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.3 | 2.7 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.3 | 1.1 | GO:0005606 | laminin-1 complex(GO:0005606) |
| 0.3 | 6.6 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 3.0 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.2 | 1.7 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 2.2 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.2 | 3.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.2 | 7.1 | GO:0098827 | endoplasmic reticulum subcompartment(GO:0098827) |
| 0.2 | 6.0 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 2.8 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.2 | 4.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.2 | 1.2 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.2 | 0.7 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.2 | 2.7 | GO:0016600 | zonula adherens(GO:0005915) flotillin complex(GO:0016600) |
| 0.2 | 10.3 | GO:0002102 | podosome(GO:0002102) |
| 0.2 | 0.7 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 1.7 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.2 | 3.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.2 | 0.8 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.2 | 1.5 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.2 | 10.4 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.2 | 3.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 5.7 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.2 | 1.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.2 | 6.0 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.2 | 3.0 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 4.4 | GO:0045120 | pronucleus(GO:0045120) |
| 0.2 | 1.7 | GO:0035770 | ribonucleoprotein granule(GO:0035770) |
| 0.2 | 2.8 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.2 | 44.9 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.2 | 22.9 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.2 | 1.4 | GO:0060091 | kinocilium(GO:0060091) |
| 0.2 | 2.1 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.2 | 1.5 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.1 | 0.4 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.1 | 15.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 1.1 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.1 | 2.7 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 1.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 3.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 15.5 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 1.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 14.5 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 2.0 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.5 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.1 | 0.6 | GO:0035363 | histone locus body(GO:0035363) |
| 0.1 | 5.7 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 7.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 1.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 1.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 1.9 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526) |
| 0.1 | 4.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 8.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 0.3 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.1 | 4.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 4.1 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.0 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 6.5 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 6.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 7.6 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 0.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.1 | 12.1 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.1 | 0.3 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.1 | 3.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 0.5 | GO:0001652 | granular component(GO:0001652) |
| 0.1 | 1.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.4 | GO:0097059 | CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059) |
| 0.1 | 7.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 0.8 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 0.7 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.1 | 1.0 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 2.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.0 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.1 | 1.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 0.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 0.9 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
| 0.1 | 4.3 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 1.1 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 6.6 | GO:0005930 | axoneme(GO:0005930) |
| 0.1 | 12.6 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 1.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 2.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 2.8 | GO:0031966 | mitochondrial membrane(GO:0031966) |
| 0.1 | 0.5 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 0.4 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 15.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.8 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.7 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 2.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 4.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 1.2 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 2.1 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 4.1 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 14.2 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) |
| 0.0 | 2.1 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 14.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 0.2 | GO:0070938 | contractile ring(GO:0070938) |
| 0.0 | 0.4 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 1.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 2.1 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 32.1 | GO:0005856 | cytoskeleton(GO:0005856) |
| 0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.0 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.2 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.2 | 36.6 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 8.2 | 24.6 | GO:0052894 | norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895) |
| 7.5 | 44.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 7.2 | 43.1 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 4.7 | 4.7 | GO:0031691 | alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) |
| 4.5 | 45.3 | GO:0004064 | arylesterase activity(GO:0004064) |
| 4.4 | 100.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 4.2 | 25.0 | GO:1990254 | keratin filament binding(GO:1990254) |
| 3.8 | 19.0 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 3.7 | 14.7 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 3.4 | 10.3 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 3.0 | 21.3 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 3.0 | 18.1 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 2.8 | 17.1 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 2.8 | 19.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 2.4 | 14.3 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 2.3 | 4.6 | GO:0032129 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 2.3 | 4.6 | GO:0001003 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 2.2 | 9.0 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 2.2 | 11.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 2.0 | 5.9 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 2.0 | 33.6 | GO:0005522 | profilin binding(GO:0005522) |
| 2.0 | 2.0 | GO:0004819 | glutamine-tRNA ligase activity(GO:0004819) |
| 2.0 | 19.7 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 1.9 | 5.6 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142) |
| 1.8 | 7.2 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 1.7 | 6.9 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 1.6 | 16.4 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 1.6 | 4.9 | GO:0019202 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
| 1.6 | 21.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 1.6 | 18.8 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 1.6 | 4.7 | GO:0000401 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 1.5 | 4.6 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 1.5 | 4.4 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 1.4 | 31.8 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 1.4 | 5.6 | GO:0030519 | snoRNP binding(GO:0030519) |
| 1.4 | 4.2 | GO:0034188 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 1.4 | 9.7 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 1.4 | 10.9 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 1.3 | 12.1 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
| 1.3 | 29.7 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 1.3 | 3.9 | GO:0005275 | amine transmembrane transporter activity(GO:0005275) |
| 1.3 | 5.1 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 1.2 | 4.9 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 1.2 | 8.1 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 1.1 | 4.4 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 1.1 | 4.3 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 1.0 | 3.1 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 1.0 | 6.2 | GO:0022858 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 1.0 | 9.2 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 1.0 | 7.1 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
| 1.0 | 14.4 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.9 | 5.7 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.9 | 4.7 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.9 | 36.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.9 | 8.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.9 | 25.1 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.9 | 27.9 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.9 | 6.5 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.9 | 12.9 | GO:0031432 | titin binding(GO:0031432) |
| 0.9 | 2.7 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.9 | 8.8 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.9 | 9.5 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.9 | 20.6 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.9 | 32.4 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.8 | 3.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.8 | 6.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.8 | 9.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.8 | 40.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.8 | 4.1 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.8 | 3.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.8 | 4.0 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.8 | 19.0 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.8 | 30.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.8 | 3.1 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.8 | 4.7 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.8 | 81.0 | GO:0005518 | collagen binding(GO:0005518) |
| 0.8 | 43.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.8 | 12.2 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.8 | 2.3 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.7 | 1.5 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.7 | 3.7 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.7 | 55.9 | GO:0070888 | E-box binding(GO:0070888) |
| 0.7 | 3.7 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.7 | 6.2 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.7 | 2.7 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.7 | 3.3 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.7 | 2.6 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.7 | 2.6 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.6 | 1.9 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.6 | 7.5 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.6 | 36.3 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.6 | 21.1 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.6 | 3.7 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.6 | 3.1 | GO:0004308 | exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.6 | 6.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.6 | 5.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.6 | 3.4 | GO:0000828 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.6 | 1.7 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
| 0.6 | 2.8 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.5 | 2.7 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.5 | 2.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.5 | 5.6 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.5 | 4.1 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.5 | 2.0 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.5 | 30.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.5 | 0.5 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.5 | 2.9 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
| 0.5 | 6.7 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.5 | 8.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.5 | 3.3 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.5 | 1.9 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.5 | 1.9 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.5 | 3.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.5 | 1.8 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.4 | 4.3 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.4 | 13.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.4 | 1.3 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.4 | 11.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.4 | 6.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 22.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.4 | 2.8 | GO:0030172 | troponin C binding(GO:0030172) troponin I binding(GO:0031013) |
| 0.4 | 1.6 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.4 | 6.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.4 | 4.8 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.4 | 4.0 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.4 | 1.6 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.4 | 4.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.4 | 8.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.4 | 13.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.4 | 6.2 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.4 | 1.8 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
| 0.4 | 8.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.4 | 1.1 | GO:0005292 | high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292) |
| 0.3 | 37.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.3 | 2.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.3 | 4.4 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.3 | 4.0 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.3 | 10.4 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.3 | 3.3 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.3 | 1.9 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.3 | 5.4 | GO:0016918 | retinal binding(GO:0016918) |
| 0.3 | 2.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.3 | 3.8 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.3 | 2.2 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.3 | 2.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.3 | 1.9 | GO:1990269 | RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269) |
| 0.3 | 3.7 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.3 | 2.5 | GO:0019158 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.3 | 26.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.3 | 8.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.3 | 1.2 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) |
| 0.3 | 9.7 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) |
| 0.3 | 2.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 22.0 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.3 | 2.4 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.3 | 6.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.3 | 9.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.3 | 4.0 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.3 | 5.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.3 | 1.7 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.3 | 3.6 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.3 | 3.0 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.3 | 3.7 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.3 | 0.8 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.3 | 2.6 | GO:0005113 | patched binding(GO:0005113) |
| 0.3 | 8.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 4.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 1.2 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.2 | 1.0 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.2 | 6.4 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 2.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.2 | 13.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.2 | 6.8 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.2 | 11.6 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.2 | 1.2 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 3.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.2 | 2.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 0.7 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 0.7 | GO:0016890 | site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890) |
| 0.2 | 2.2 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 5.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.2 | 5.0 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.2 | 1.6 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 1.2 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.2 | 4.8 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.2 | 4.0 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.2 | 5.1 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.2 | 1.7 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.2 | 1.5 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.2 | 3.7 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.2 | 3.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.2 | 3.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.2 | 13.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.2 | 2.3 | GO:0052813 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.2 | 39.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.2 | 6.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.2 | 4.8 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.2 | 0.8 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.2 | 7.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.2 | 1.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 2.8 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.2 | 3.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 8.7 | GO:0042805 | actinin binding(GO:0042805) |
| 0.2 | 1.7 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.2 | 1.1 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.2 | 0.8 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.2 | 2.4 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.2 | 5.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 1.5 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 4.4 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 5.9 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 1.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 7.7 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 16.5 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 7.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 2.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 2.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 2.4 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.1 | 1.3 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 1.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 1.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.4 | GO:0004945 | angiotensin type II receptor activity(GO:0004945) |
| 0.1 | 5.5 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 2.6 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.1 | 2.3 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 0.1 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.1 | 42.5 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 17.8 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 14.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 0.2 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 1.8 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 0.7 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 1.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 1.7 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 0.8 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.4 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 0.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 2.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.5 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 0.5 | GO:0019209 | kinase activator activity(GO:0019209) |
| 0.1 | 0.2 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 1.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 2.2 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.1 | 0.4 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
| 0.1 | 5.1 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.1 | 0.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 0.3 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.1 | 1.7 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 10.4 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.1 | 1.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.5 | GO:0051733 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 0.1 | 0.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 2.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 3.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 1.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 3.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 1.6 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 3.6 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 5.9 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 0.6 | GO:0015288 | porin activity(GO:0015288) |
| 0.1 | 0.7 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 1.4 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.1 | 0.9 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 1.1 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 1.7 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 2.4 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.4 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 1.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 1.1 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.1 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.0 | 66.1 | GO:0003723 | RNA binding(GO:0003723) |
| 0.0 | 0.1 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.0 | 13.0 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 0.7 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 1.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.6 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.1 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 0.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.8 | GO:0052866 | phosphatidylinositol phosphate phosphatase activity(GO:0052866) |
| 0.0 | 0.5 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.0 | 0.3 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 3.9 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 2.1 | GO:0015405 | primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.0 | 0.3 | GO:0042166 | acetylcholine binding(GO:0042166) |
| 0.0 | 0.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.5 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.2 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 1.6 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 6.5 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 1.2 | 23.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 1.1 | 63.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 1.1 | 22.6 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 1.0 | 57.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 1.0 | 2.0 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 1.0 | 19.7 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 1.0 | 98.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.8 | 44.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.7 | 28.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.7 | 23.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.7 | 16.8 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.6 | 18.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.6 | 22.5 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.5 | 10.8 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.5 | 17.0 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.5 | 25.9 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.5 | 10.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.5 | 32.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.5 | 33.1 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.5 | 15.1 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.4 | 4.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.4 | 7.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.4 | 26.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.4 | 5.9 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.4 | 5.3 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.3 | 11.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.3 | 18.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.3 | 2.7 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.3 | 5.6 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.3 | 10.1 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.3 | 60.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 5.5 | PID ATM PATHWAY | ATM pathway |
| 0.3 | 6.3 | PID MYC PATHWAY | C-MYC pathway |
| 0.2 | 7.2 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.2 | 10.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.2 | 2.6 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.2 | 8.9 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.2 | 7.2 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 9.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.2 | 9.3 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.2 | 3.1 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.2 | 15.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 5.3 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.2 | 3.5 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.2 | 2.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 4.3 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.1 | 12.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 2.5 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 9.1 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 3.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 4.4 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.1 | 3.1 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 2.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 8.5 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 2.8 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 2.4 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.1 | 7.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.9 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 1.0 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 3.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 6.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 3.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 4.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 0.9 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.1 | 7.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 1.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 1.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 0.9 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 2.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 0.6 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 1.7 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.9 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 2.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.5 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.8 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.8 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 1.1 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 28.0 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 2.0 | 22.0 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 2.0 | 31.9 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 2.0 | 43.1 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 1.5 | 27.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 1.5 | 32.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 1.4 | 21.3 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 1.4 | 28.9 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 1.3 | 38.8 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 1.2 | 29.4 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.9 | 29.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.9 | 40.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.9 | 9.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.8 | 13.2 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.8 | 3.1 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.7 | 6.5 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.7 | 34.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.7 | 34.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.7 | 32.7 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.6 | 32.3 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.6 | 23.3 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.5 | 69.2 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.5 | 16.3 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.5 | 10.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.5 | 8.6 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.5 | 7.8 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.4 | 14.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.4 | 19.0 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.4 | 5.3 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.4 | 38.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.4 | 4.7 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.4 | 2.6 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.4 | 4.8 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.4 | 4.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.4 | 60.7 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.4 | 9.9 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.4 | 36.5 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.3 | 5.5 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.3 | 18.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.3 | 24.6 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.3 | 3.3 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.3 | 17.3 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.3 | 5.4 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.3 | 34.2 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.3 | 4.6 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.3 | 1.0 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.2 | 10.6 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.2 | 15.6 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.2 | 3.7 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 4.1 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.2 | 6.7 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.2 | 6.2 | REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
| 0.2 | 1.5 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.2 | 9.6 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.2 | 2.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.2 | 4.4 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.2 | 12.7 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 4.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.2 | 12.8 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 4.2 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.2 | 1.0 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.2 | 1.9 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.2 | 8.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 4.4 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.1 | 3.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 10.1 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.1 | 3.7 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.1 | 14.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 2.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 2.3 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.1 | 0.1 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.1 | 2.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 4.7 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.1 | 0.3 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.1 | 0.7 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 0.5 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 3.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.1 | 1.8 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 2.4 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 0.1 | 0.8 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 1.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 3.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 3.4 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 1.2 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.6 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 1.0 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 6.3 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 2.8 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.0 | 0.7 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.5 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 1.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.9 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.3 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.3 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 0.4 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.3 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.1 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.1 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 0.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.4 | REACTOME INTERFERON SIGNALING | Genes involved in Interferon Signaling |
| 0.0 | 0.5 | REACTOME TRANSLATION | Genes involved in Translation |