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GSE58827: Dynamics of the Mouse Liver

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Results for Sox6_Sox9

Z-value: 0.81

Motif logo

Transcription factors associated with Sox6_Sox9

Gene Symbol Gene ID Gene Info
ENSMUSG00000051910.14 SRY (sex determining region Y)-box 6
ENSMUSG00000000567.6 SRY (sex determining region Y)-box 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox9mm39_v1_chr11_+_112673041_1126730590.692.6e-06Click!
Sox6mm39_v1_chr7_-_115445315_115445347-0.316.7e-02Click!

Activity profile of Sox6_Sox9 motif

Sorted Z-values of Sox6_Sox9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_46749370 4.58 ENSMUST00000087012.7
solute carrier family 22 (organic anion transporter), member 7
chr4_+_140970161 3.94 ENSMUST00000138096.8
ENSMUST00000006618.9
ENSMUST00000125392.8
Rho guanine nucleotide exchange factor (GEF) 19
chr14_-_52151537 3.18 ENSMUST00000227402.2
ENSMUST00000227237.2
N-myc downstream regulated gene 2
chr3_+_20011251 3.16 ENSMUST00000108328.8
ceruloplasmin
chr13_-_93774469 3.08 ENSMUST00000099309.6
betaine-homocysteine methyltransferase
chr3_+_20011405 3.02 ENSMUST00000108325.9
ceruloplasmin
chr3_+_20011201 2.73 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr19_-_4384029 2.62 ENSMUST00000176653.2
lysine (K)-specific demethylase 2A
chr4_+_134123631 2.28 ENSMUST00000105869.9
platelet-activating factor acetylhydrolase 2
chr6_+_82018604 2.28 ENSMUST00000042974.15
eva-1 homolog A (C. elegans)
chr6_-_47790272 2.24 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr3_-_116762476 2.19 ENSMUST00000119557.8
palmdelphin
chr9_+_13677266 1.92 ENSMUST00000152532.8
myotubularin related protein 2
chr17_+_31605184 1.79 ENSMUST00000047168.13
ENSMUST00000127929.8
ENSMUST00000134525.9
ENSMUST00000236454.2
ENSMUST00000238091.2
ENSMUST00000235719.2
phosphodiesterase 9A
chr16_+_22739028 1.78 ENSMUST00000232097.2
fetuin beta
chr6_+_34575435 1.72 ENSMUST00000079391.10
ENSMUST00000142512.8
ENSMUST00000115027.8
ENSMUST00000115026.8
caldesmon 1
chr15_+_25622611 1.69 ENSMUST00000110457.8
ENSMUST00000137601.8
myosin X
chr9_-_64928927 1.66 ENSMUST00000036615.7
3-hydroxyacyl-CoA dehydratase 3
chr7_+_78922947 1.66 ENSMUST00000037315.13
abhydrolase domain containing 2
chr8_+_22996233 1.65 ENSMUST00000210854.2
solute carrier family 20, member 2
chr5_-_105491795 1.59 ENSMUST00000171587.2
guanylate binding protein 11
chr11_-_106605772 1.55 ENSMUST00000124958.3
platelet/endothelial cell adhesion molecule 1
chr11_-_106469938 1.41 ENSMUST00000103070.3
testis expressed gene 2
chr8_+_46944000 1.40 ENSMUST00000110372.9
ENSMUST00000130563.2
acyl-CoA synthetase long-chain family member 1
chr9_+_7764042 1.37 ENSMUST00000052865.16
transmembrane protein 123
chr8_+_45960804 1.37 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr13_-_4200627 1.35 ENSMUST00000110704.9
ENSMUST00000021635.9
aldo-keto reductase family 1, member C18
chr10_+_96453408 1.35 ENSMUST00000218953.2
BTG anti-proliferation factor 1
chr16_+_31482658 1.33 ENSMUST00000115201.8
discs large MAGUK scaffold protein 1
chr14_+_5894220 1.32 ENSMUST00000063750.8
retinoic acid receptor, beta
chr5_-_123320767 1.30 ENSMUST00000154713.8
ENSMUST00000031398.14
4-hydroxyphenylpyruvic acid dioxygenase
chr6_+_54249817 1.29 ENSMUST00000204921.3
ENSMUST00000203091.3
ENSMUST00000204115.3
ENSMUST00000203941.3
ENSMUST00000204746.2
chimerin 2
chr7_-_126275529 1.29 ENSMUST00000106372.11
ENSMUST00000155419.3
ENSMUST00000106373.9
sulfotransferase family 1A, phenol-preferring, member 1
chr6_-_93889483 1.28 ENSMUST00000205116.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr4_-_63073028 1.26 ENSMUST00000142901.2
alpha 1 microglobulin/bikunin precursor
chr11_+_101258368 1.25 ENSMUST00000019469.3
glucose-6-phosphatase, catalytic
chr3_-_116762617 1.24 ENSMUST00000143611.2
ENSMUST00000040097.14
palmdelphin
chr6_+_17463748 1.23 ENSMUST00000115443.8
met proto-oncogene
chr11_+_93935021 1.22 ENSMUST00000075695.13
ENSMUST00000092777.11
sperm associated antigen 9
chr16_+_31482745 1.22 ENSMUST00000100001.10
ENSMUST00000064477.14
discs large MAGUK scaffold protein 1
chr18_-_16942289 1.21 ENSMUST00000025166.14
cadherin 2
chr8_+_11362805 1.21 ENSMUST00000033899.14
collagen, type IV, alpha 2
chr1_-_155022501 1.20 ENSMUST00000027744.10
major histocompatibility complex, class I-related
chr11_-_106606076 1.17 ENSMUST00000080853.11
ENSMUST00000183610.8
ENSMUST00000103069.10
ENSMUST00000106796.9
platelet/endothelial cell adhesion molecule 1
chr1_-_72914036 1.17 ENSMUST00000027377.9
insulin-like growth factor binding protein 5
chr9_+_54771064 1.16 ENSMUST00000034843.9
iron responsive element binding protein 2
chr9_+_108924457 1.15 ENSMUST00000072093.13
plexin B1
chr8_-_11362731 1.15 ENSMUST00000033898.10
collagen, type IV, alpha 1
chr11_-_11840367 1.13 ENSMUST00000155690.2
dopa decarboxylase
chr11_-_30218167 1.12 ENSMUST00000006629.14
spectrin beta, non-erythrocytic 1
chr15_+_75468473 1.10 ENSMUST00000189944.7
ENSMUST00000023243.11
GPI-anchored HDL-binding protein 1
chr1_+_62742444 1.10 ENSMUST00000102822.9
ENSMUST00000075144.12
neuropilin 2
chr4_-_104967032 1.09 ENSMUST00000030243.8
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr11_-_11840394 1.09 ENSMUST00000109659.9
dopa decarboxylase
chr2_-_160208977 1.08 ENSMUST00000099126.5
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr12_+_29988035 1.05 ENSMUST00000122328.8
ENSMUST00000118321.3
peroxidasin
chr2_-_65068917 1.04 ENSMUST00000090896.10
ENSMUST00000155082.2
Cobl-like 1
chr15_+_59520199 1.01 ENSMUST00000067543.8
tribbles pseudokinase 1
chr14_-_33169099 1.00 ENSMUST00000111944.10
ENSMUST00000022504.12
ENSMUST00000111945.9
mitogen-activated protein kinase 8
chr8_+_45960931 1.00 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr12_+_40495951 0.99 ENSMUST00000037488.8
dedicator of cytokinesis 4
chr16_+_31482949 0.99 ENSMUST00000023454.12
discs large MAGUK scaffold protein 1
chr16_+_34815177 0.98 ENSMUST00000231589.2
myosin, light polypeptide kinase
chr1_-_97689263 0.97 ENSMUST00000171129.8
diphosphoinositol pentakisphosphate kinase 2
chr16_+_78098344 0.96 ENSMUST00000232148.2
ENSMUST00000023572.15
coxsackie virus and adenovirus receptor
chr4_+_137720326 0.96 ENSMUST00000139759.8
ENSMUST00000058133.10
ENSMUST00000105830.9
ENSMUST00000084215.12
eukaryotic translation initiation factor 4 gamma, 3
chr3_+_135531548 0.95 ENSMUST00000167390.8
solute carrier family 39 (metal ion transporter), member 8
chr6_+_54016543 0.94 ENSMUST00000046856.14
chimerin 2
chr15_-_37458768 0.94 ENSMUST00000116445.9
neurocalcin delta
chr2_+_67948057 0.92 ENSMUST00000112346.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr6_-_129449739 0.92 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr10_+_41395870 0.92 ENSMUST00000189300.2
CD164 antigen
chr10_-_24712034 0.90 ENSMUST00000218044.2
ENSMUST00000020169.9
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr12_+_31315270 0.88 ENSMUST00000002979.16
ENSMUST00000239496.2
ENSMUST00000170495.3
laminin B1
chr6_+_48570817 0.87 ENSMUST00000154010.8
ENSMUST00000009420.15
ENSMUST00000163452.7
ENSMUST00000118229.2
ENSMUST00000135151.3
replication initiator 1
chr11_+_93935066 0.87 ENSMUST00000103168.10
sperm associated antigen 9
chr2_+_67935015 0.87 ENSMUST00000042456.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr13_+_81034214 0.86 ENSMUST00000161441.2
arrestin domain containing 3
chr2_+_102489558 0.85 ENSMUST00000111213.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_102488985 0.84 ENSMUST00000080210.10
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_127399776 0.84 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_+_39940189 0.83 ENSMUST00000191761.6
ENSMUST00000193682.6
ENSMUST00000195860.6
ENSMUST00000195259.6
ENSMUST00000195636.6
ENSMUST00000192509.6
mitogen-activated protein kinase kinase kinase kinase 4
chr15_+_75468494 0.82 ENSMUST00000189874.2
GPI-anchored HDL-binding protein 1
chr14_+_63075127 0.82 ENSMUST00000014691.10
WD repeat and FYVE domain containing 2
chr15_-_10713621 0.80 ENSMUST00000090339.11
retinoic acid induced 14
chr1_+_24717968 0.79 ENSMUST00000095062.10
LMBR1 domain containing 1
chr7_-_37722938 0.79 ENSMUST00000206581.2
URI1, prefoldin-like chaperone
chr15_+_6416079 0.79 ENSMUST00000080880.12
disabled 2, mitogen-responsive phosphoprotein
chr9_+_74883377 0.78 ENSMUST00000081746.7
family with sequence similarity 214, member A
chr5_+_65288418 0.78 ENSMUST00000101191.10
ENSMUST00000204348.3
kelch-like 5
chr7_+_128290204 0.78 ENSMUST00000118605.2
inositol polyphosphate-5-phosphatase F
chr15_+_6416229 0.78 ENSMUST00000110664.9
ENSMUST00000110663.9
ENSMUST00000161812.8
ENSMUST00000160134.8
disabled 2, mitogen-responsive phosphoprotein
chr11_-_68848271 0.77 ENSMUST00000108671.2
Rho guanine nucleotide exchange factor (GEF) 15
chr1_+_176642226 0.75 ENSMUST00000056773.15
ENSMUST00000027785.15
serologically defined colon cancer antigen 8
chr18_-_60881679 0.74 ENSMUST00000237783.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_-_63072367 0.74 ENSMUST00000030041.5
alpha 1 microglobulin/bikunin precursor
chr7_-_110681402 0.74 ENSMUST00000159305.2
eukaryotic translation initiation factor 4, gamma 2
chrX_+_100427331 0.74 ENSMUST00000119190.2
gap junction protein, beta 1
chrX_+_76554608 0.73 ENSMUST00000088217.12
transducin (beta)-like 1 X-linked
chr15_-_90934059 0.73 ENSMUST00000109288.9
ENSMUST00000100304.11
kinesin family member 21A
chr15_+_41694317 0.70 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chrX_+_99811325 0.70 ENSMUST00000000901.13
ENSMUST00000113736.9
ENSMUST00000087984.11
discs large MAGUK scaffold protein 3
chr16_-_22847760 0.69 ENSMUST00000039338.13
kininogen 2
chrX_-_23151771 0.69 ENSMUST00000115319.9
kelch-like 13
chr18_+_32055339 0.69 ENSMUST00000233994.2
LIM and senescent cell antigen like domains 2
chr4_+_137720755 0.68 ENSMUST00000084214.12
ENSMUST00000105831.9
ENSMUST00000203828.3
eukaryotic translation initiation factor 4 gamma, 3
chr5_-_146521629 0.68 ENSMUST00000200112.2
ENSMUST00000197431.2
ENSMUST00000197825.2
G-protein coupled receptor 12
chr6_+_143112936 0.67 ENSMUST00000204947.3
ENSMUST00000032413.7
ENSMUST00000205256.2
ethanolamine kinase 1
chr16_-_22847829 0.67 ENSMUST00000100046.9
kininogen 2
chr6_-_87312743 0.66 ENSMUST00000042025.12
ENSMUST00000205033.2
anthrax toxin receptor 1
chr11_+_29642937 0.65 ENSMUST00000102843.10
ENSMUST00000102842.10
ENSMUST00000078830.11
ENSMUST00000170731.8
reticulon 4
chr6_+_17463819 0.65 ENSMUST00000140070.8
met proto-oncogene
chr19_+_32734884 0.65 ENSMUST00000013807.8
phosphatase and tensin homolog
chr10_+_80003612 0.64 ENSMUST00000105365.9
cold inducible RNA binding protein
chr5_+_88712840 0.64 ENSMUST00000196894.5
ENSMUST00000198965.5
RUN and FYVE domain containing 3
chr16_-_22847808 0.64 ENSMUST00000115349.9
kininogen 2
chr9_-_75316625 0.64 ENSMUST00000168937.8
mitogen-activated protein kinase 6
chr13_-_18118736 0.64 ENSMUST00000009003.9
v-ral simian leukemia viral oncogene A (ras related)
chr15_+_34082805 0.63 ENSMUST00000022865.17
metadherin
chr12_+_31315227 0.62 ENSMUST00000169088.8
laminin B1
chr17_+_53873964 0.62 ENSMUST00000000724.15
K(lysine) acetyltransferase 2B
chr1_+_153776323 0.61 ENSMUST00000140685.4
ENSMUST00000139476.8
glutamate-ammonia ligase (glutamine synthetase)
chr17_-_34340918 0.61 ENSMUST00000151986.2
bromodomain containing 2
chr17_+_47747657 0.60 ENSMUST00000150819.3
expressed sequence AI661453
chr14_-_56499690 0.60 ENSMUST00000015581.6
granzyme B
chr16_-_22848153 0.60 ENSMUST00000232459.2
kininogen 2
chr16_-_23807602 0.59 ENSMUST00000023151.6
B cell leukemia/lymphoma 6
chr4_+_94627755 0.58 ENSMUST00000071168.6
TEK receptor tyrosine kinase
chr5_+_3978266 0.58 ENSMUST00000044492.10
A kinase (PRKA) anchor protein (yotiao) 9
chr16_+_78098626 0.58 ENSMUST00000114229.4
ENSMUST00000231356.2
coxsackie virus and adenovirus receptor
chr1_+_24717793 0.58 ENSMUST00000186190.2
LMBR1 domain containing 1
chr8_+_26008773 0.58 ENSMUST00000084027.13
ENSMUST00000178276.8
ENSMUST00000179592.8
fibroblast growth factor receptor 1
chr9_-_32452885 0.58 ENSMUST00000016231.14
Friend leukemia integration 1
chr5_+_124939739 0.57 ENSMUST00000111417.9
zinc finger protein 664
chr18_+_67338437 0.57 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr8_-_85526653 0.56 ENSMUST00000126806.2
ENSMUST00000076715.13
nuclear factor I/X
chr12_-_83643964 0.55 ENSMUST00000048319.6
zinc finger, FYVE domain containing 1
chr8_+_26008799 0.54 ENSMUST00000119398.10
ENSMUST00000117179.9
fibroblast growth factor receptor 1
chr1_-_151376544 0.54 ENSMUST00000187991.2
ENSMUST00000187048.7
ENSMUST00000186415.7
ring finger protein 2
chr2_+_6327431 0.53 ENSMUST00000114937.8
USP6 N-terminal like
chr19_-_32080496 0.53 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr3_-_116601700 0.53 ENSMUST00000159742.8
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr5_+_138170259 0.52 ENSMUST00000019662.11
ENSMUST00000151318.8
adaptor-related protein complex AP-4, mu 1
chrX_-_103457431 0.52 ENSMUST00000033695.6
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr1_-_46927230 0.52 ENSMUST00000185520.2
solute carrier family 39 (zinc transporter), member 10
chr7_-_129867967 0.51 ENSMUST00000117872.8
ENSMUST00000120187.9
fibroblast growth factor receptor 2
chr16_+_23044763 0.51 ENSMUST00000178797.8
beta galactoside alpha 2,6 sialyltransferase 1
chr17_+_37504783 0.51 ENSMUST00000038844.7
ubiquitin D
chr10_+_79986988 0.50 ENSMUST00000146516.8
ENSMUST00000144526.2
midnolin
chr11_+_48967411 0.50 ENSMUST00000109202.3
interferon gamma inducible protein 47
chr12_-_58315949 0.49 ENSMUST00000062254.4
C-type lectin domain family 14, member a
chr17_-_32074754 0.49 ENSMUST00000024839.6
salt inducible kinase 1
chr10_-_59277570 0.49 ENSMUST00000009798.5
oncoprotein induced transcript 3
chr12_+_117652526 0.49 ENSMUST00000222185.2
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_84481058 0.49 ENSMUST00000111670.9
ENSMUST00000111697.9
ENSMUST00000111696.8
ENSMUST00000111678.8
ENSMUST00000111690.8
ENSMUST00000111695.8
ENSMUST00000111677.8
ENSMUST00000111698.8
ENSMUST00000099941.9
ENSMUST00000111676.8
ENSMUST00000111694.8
ENSMUST00000111675.8
ENSMUST00000111689.8
ENSMUST00000111687.8
ENSMUST00000111692.8
ENSMUST00000111685.8
ENSMUST00000111686.8
ENSMUST00000111688.8
ENSMUST00000111693.8
ENSMUST00000111684.8
catenin (cadherin associated protein), delta 1
chr6_+_51409643 0.48 ENSMUST00000005103.12
nuclear factor, erythroid derived 2, like 3
chr4_-_135600854 0.48 ENSMUST00000142585.2
proline-rich nuclear receptor coactivator 2
chr1_-_168259264 0.47 ENSMUST00000176790.8
pre B cell leukemia homeobox 1
chr12_-_83643883 0.46 ENSMUST00000221919.2
zinc finger, FYVE domain containing 1
chr5_-_92231517 0.46 ENSMUST00000202258.4
ENSMUST00000113127.7
GTPase activating protein (SH3 domain) binding protein 2
chr5_-_92231314 0.46 ENSMUST00000169094.8
ENSMUST00000167918.8
GTPase activating protein (SH3 domain) binding protein 2
chr11_-_31621727 0.45 ENSMUST00000109415.2
biorientation of chromosomes in cell division 1
chr10_-_37014859 0.45 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr3_+_135531834 0.45 ENSMUST00000029810.6
solute carrier family 39 (metal ion transporter), member 8
chr17_-_71158052 0.45 ENSMUST00000186358.6
TGFB-induced factor homeobox 1
chrX_-_112095181 0.44 ENSMUST00000026607.15
ENSMUST00000113388.3
choroidermia (RAB escort protein 1)
chr2_-_35994072 0.44 ENSMUST00000112961.10
ENSMUST00000112966.10
LIM homeobox protein 6
chr6_-_116084810 0.44 ENSMUST00000204353.3
transmembrane and coiled coil domains 1
chr11_-_31621863 0.44 ENSMUST00000058060.14
biorientation of chromosomes in cell division 1
chr19_+_46611826 0.43 ENSMUST00000111855.5
WW domain binding protein 1 like
chr17_-_24863907 0.43 ENSMUST00000234505.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_+_75105282 0.43 ENSMUST00000207750.2
ENSMUST00000166315.7
A kinase (PRKA) anchor protein 13
chr6_-_124718316 0.43 ENSMUST00000004389.6
gene rich cluster, C10 gene
chr11_-_62283431 0.43 ENSMUST00000151498.9
nuclear receptor co-repressor 1
chr17_-_24863956 0.42 ENSMUST00000019684.13
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr8_-_71848429 0.42 ENSMUST00000049184.9
USH1 protein network component harmonin binding protein 1
chr19_+_5088854 0.42 ENSMUST00000053705.8
ENSMUST00000235776.2
beta-1,4-glucuronyltransferase 1
chr11_+_93935156 0.42 ENSMUST00000024979.15
sperm associated antigen 9
chr11_+_32405367 0.42 ENSMUST00000051053.5
ubiquitin domain containing 2
chr11_-_6224830 0.41 ENSMUST00000132147.3
ENSMUST00000004508.13
transmembrane p24 trafficking protein 4
chr7_-_127214372 0.41 ENSMUST00000128731.8
ENSMUST00000122066.8
zinc finger protein 629
chr12_-_83609217 0.40 ENSMUST00000222448.2
zinc finger, FYVE domain containing 1
chr11_+_51152546 0.40 ENSMUST00000130641.8
CDC like kinase 4
chr2_-_146353819 0.40 ENSMUST00000131824.8
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr9_+_110361561 0.40 ENSMUST00000153838.8
SET domain containing 2
chr11_-_49077986 0.40 ENSMUST00000046522.13
butyrophilin-like 9
chr12_+_25024913 0.39 ENSMUST00000066652.7
ENSMUST00000220459.2
ENSMUST00000222941.2
kinase D-interacting substrate 220
chr7_+_119499322 0.39 ENSMUST00000106516.2
LYR motif containing 1
chr7_-_127214398 0.39 ENSMUST00000134446.8
ENSMUST00000084564.10
zinc finger protein 629
chr3_-_116601815 0.39 ENSMUST00000040603.14
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr1_-_173703424 0.39 ENSMUST00000186442.7
myeloid nuclear differentiation antigen like
chr10_+_62896492 0.38 ENSMUST00000219687.2
ENSMUST00000219045.2
phenazine biosynthesis-like protein domain containing 1
chr18_-_75094323 0.38 ENSMUST00000066532.5
lipase, endothelial
chr18_+_4921663 0.38 ENSMUST00000143254.8
supervillin
chr1_-_160040286 0.37 ENSMUST00000195654.2
ENSMUST00000014370.11
calcyclin binding protein
chr2_-_146353911 0.37 ENSMUST00000109986.9
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr17_+_47747540 0.37 ENSMUST00000037701.13
expressed sequence AI661453
chr1_+_39940043 0.37 ENSMUST00000168431.7
ENSMUST00000163854.9
mitogen-activated protein kinase kinase kinase kinase 4
chr9_-_106666329 0.36 ENSMUST00000046502.7
RAD54 like 2 (S. cerevisiae)
chr5_+_34706936 0.35 ENSMUST00000179943.3
SH3-domain binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox6_Sox9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.9 3.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.7 2.2 GO:1903334 positive regulation of protein folding(GO:1903334)
0.6 1.9 GO:0090320 regulation of chylomicron remnant clearance(GO:0090320)
0.5 3.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.5 3.1 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.5 1.4 GO:0009753 sesquiterpenoid metabolic process(GO:0006714) response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 1.3 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.4 1.2 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.4 1.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4 1.1 GO:1903465 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.4 1.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 1.4 GO:0038016 insulin receptor internalization(GO:0038016)
0.3 2.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 2.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 1.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.3 2.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 1.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 0.9 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 1.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3 1.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 2.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.3 8.9 GO:0046688 response to copper ion(GO:0046688)
0.2 1.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 1.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.2 1.8 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.4 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.2 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.6 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.5 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365)
0.2 0.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.2 0.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.6 GO:0043379 memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380)
0.1 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.6 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 2.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1 4.6 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.8 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 1.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.8 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 1.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 1.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 1.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.8 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.1 0.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.5 GO:1990743 protein sialylation(GO:1990743)
0.1 0.4 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 1.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.0 GO:0051923 sulfation(GO:0051923)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 1.7 GO:0032570 response to progesterone(GO:0032570)
0.1 1.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.8 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.2 GO:0055089 fatty acid homeostasis(GO:0055089)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.6 GO:0051665 membrane raft localization(GO:0051665)
0.1 1.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.1 GO:0000239 pachytene(GO:0000239)
0.1 0.9 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 1.3 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.9 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 1.0 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 2.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.9 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 2.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.0 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 1.2 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.1 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:1901673 viral budding via host ESCRT complex(GO:0039702) regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.0 1.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.4 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.6 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 1.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.2 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.0 0.6 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 0.3 GO:0010596 negative regulation of endothelial cell migration(GO:0010596)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 1.0 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 2.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.3 GO:2000772 regulation of cellular senescence(GO:2000772)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005607 laminin-2 complex(GO:0005607)
0.4 3.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 2.4 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 1.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 2.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.2 1.1 GO:0032437 cuticular plate(GO:0032437)
0.2 1.7 GO:0030478 actin cap(GO:0030478)
0.1 2.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 9.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0044307 dendritic branch(GO:0044307)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 1.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.2 GO:0016342 catenin complex(GO:0016342)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.8 GO:0005915 zonula adherens(GO:0005915)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 2.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.6 GO:0097386 glial cell projection(GO:0097386)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.7 GO:0043197 dendritic spine(GO:0043197)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 2.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.5 GO:0016234 inclusion body(GO:0016234)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 2.2 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.5 3.5 GO:0097016 L27 domain binding(GO:0097016)
0.5 1.9 GO:0019862 IgA binding(GO:0019862)
0.5 1.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.5 1.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 1.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 2.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 1.3 GO:0008127 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868) quercetin 2,3-dioxygenase activity(GO:0008127)
0.4 1.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.4 3.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.4 1.9 GO:0035478 chylomicron binding(GO:0035478)
0.3 1.0 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.3 1.7 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3 1.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 1.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 1.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 1.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 0.9 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.2 0.6 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.2 0.8 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.2 1.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.9 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 1.2 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 2.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 0.8 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 2.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 4.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.5 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 2.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 1.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.9 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.3 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.1 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 1.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 4.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 1.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 8.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.8 PID FOXO PATHWAY FoxO family signaling
0.0 1.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 11.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 5.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 3.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 5.1 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination