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GSE58827: Dynamics of the Mouse Liver
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Results for Sp2
Z-value: 0.92
Motif logo
Transcription factors associated with Sp2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Sp2
|
ENSMUSG00000018678.14 | Sp2 transcription factor |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sp2 | mm39_v1_chr11_-_96868483_96868537 | 0.43 | 8.1e-03 | Click! |
Activity profile of Sp2 motif
Sorted Z-values of Sp2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of Sp2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.3 | GO:0010269 | response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269) |
| 0.7 | 2.1 | GO:0019413 | acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542) |
| 0.7 | 4.2 | GO:0070458 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 0.7 | 2.0 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.6 | 4.8 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.5 | 2.7 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 0.5 | 2.7 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 0.5 | 5.3 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.5 | 2.1 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.5 | 1.6 | GO:0098749 | cerebellar neuron development(GO:0098749) |
| 0.5 | 6.1 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) |
| 0.5 | 1.9 | GO:1905077 | negative regulation of interleukin-17 secretion(GO:1905077) |
| 0.4 | 2.2 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.4 | 3.8 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.4 | 6.4 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.4 | 2.3 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.3 | 1.7 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.3 | 0.9 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
| 0.3 | 0.9 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) |
| 0.3 | 1.1 | GO:1904578 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.3 | 1.3 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 2.1 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.2 | 3.0 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.2 | 3.4 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 0.2 | 1.3 | GO:0002554 | serotonin secretion by platelet(GO:0002554) |
| 0.2 | 0.7 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.2 | 1.2 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
| 0.2 | 1.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.2 | 0.8 | GO:0035795 | negative regulation of mitochondrial membrane permeability(GO:0035795) |
| 0.2 | 0.8 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 0.2 | 1.5 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 0.2 | 1.3 | GO:0015871 | choline transport(GO:0015871) |
| 0.2 | 1.3 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.2 | 1.3 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.2 | 0.7 | GO:0090290 | positive regulation of osteoclast proliferation(GO:0090290) |
| 0.2 | 1.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.2 | 1.2 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.2 | 2.4 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.2 | 1.4 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.2 | 0.8 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.2 | 1.2 | GO:0015919 | peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046) |
| 0.2 | 2.6 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.1 | 1.5 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.1 | 0.4 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.1 | 0.4 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.1 | 0.4 | GO:0097037 | heme export(GO:0097037) |
| 0.1 | 1.0 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.1 | 0.4 | GO:0035037 | sperm entry(GO:0035037) |
| 0.1 | 1.3 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 0.6 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 0.4 | GO:0040040 | thermosensory behavior(GO:0040040) |
| 0.1 | 1.4 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 0.1 | 0.9 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.1 | 0.5 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 1.2 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 0.7 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.3 | GO:0061723 | glycophagy(GO:0061723) |
| 0.1 | 0.9 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.1 | 1.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 1.6 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.1 | 0.4 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 0.3 | GO:0002017 | regulation of blood volume by renal aldosterone(GO:0002017) |
| 0.1 | 0.4 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.1 | 0.5 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.1 | 1.6 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 0.4 | GO:0009197 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
| 0.1 | 0.4 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.1 | 0.3 | GO:2000387 | regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388) negative regulation of eosinophil migration(GO:2000417) |
| 0.1 | 0.2 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 0.1 | 1.5 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 0.1 | 0.5 | GO:1901228 | positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 0.1 | 0.9 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 1.1 | GO:0048199 | vesicle targeting, to, from or within Golgi(GO:0048199) |
| 0.1 | 0.3 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.1 | 0.2 | GO:0061366 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.1 | 0.3 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.1 | 0.5 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
| 0.1 | 0.4 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
| 0.1 | 0.8 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 0.5 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.1 | 0.3 | GO:0018201 | peptidyl-glycine modification(GO:0018201) |
| 0.1 | 0.6 | GO:0000056 | ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056) |
| 0.1 | 0.2 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.1 | 0.8 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.1 | 0.7 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.5 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
| 0.1 | 0.4 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.4 | GO:0050760 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.1 | 1.1 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 0.9 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.1 | 1.3 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.1 | 0.6 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 0.2 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
| 0.1 | 0.4 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.1 | 0.2 | GO:0021558 | trochlear nerve development(GO:0021558) |
| 0.1 | 0.2 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.1 | 0.2 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.1 | 0.3 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.1 | 0.3 | GO:0060577 | pulmonary vein morphogenesis(GO:0060577) |
| 0.1 | 0.3 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.1 | 0.3 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.1 | 0.6 | GO:0061072 | voluntary musculoskeletal movement(GO:0050882) iris morphogenesis(GO:0061072) |
| 0.1 | 3.6 | GO:0006414 | translational elongation(GO:0006414) |
| 0.1 | 1.2 | GO:0070633 | transepithelial transport(GO:0070633) |
| 0.1 | 0.6 | GO:1902856 | negative regulation of nonmotile primary cilium assembly(GO:1902856) |
| 0.1 | 0.7 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 1.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.4 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.1 | 0.4 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 0.5 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
| 0.1 | 0.8 | GO:0090261 | positive regulation of inclusion body assembly(GO:0090261) |
| 0.1 | 2.0 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 0.6 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 1.0 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.1 | 0.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.1 | 0.8 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.6 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 1.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 0.7 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.3 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.0 | 0.1 | GO:1904456 | negative regulation of neuronal action potential(GO:1904456) |
| 0.0 | 2.5 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 0.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.0 | 1.1 | GO:0006924 | activation-induced cell death of T cells(GO:0006924) |
| 0.0 | 0.4 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.6 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 1.5 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.0 | 0.6 | GO:0045086 | positive regulation of interleukin-2 biosynthetic process(GO:0045086) |
| 0.0 | 0.2 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.0 | 3.1 | GO:0009250 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.2 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.0 | 0.3 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.0 | 0.2 | GO:0032290 | peripheral nervous system myelin formation(GO:0032290) |
| 0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.0 | 1.0 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 1.3 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.0 | 0.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 0.4 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
| 0.0 | 0.4 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.0 | 0.5 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.0 | 0.4 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 0.9 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.0 | 0.5 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.2 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) |
| 0.0 | 0.2 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.0 | 0.1 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.0 | 0.1 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.0 | 1.2 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.8 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.0 | 1.7 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.3 | GO:0060526 | prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527) |
| 0.0 | 1.1 | GO:0007099 | centriole replication(GO:0007099) |
| 0.0 | 0.2 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.0 | 0.6 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 1.1 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.0 | 0.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 1.4 | GO:0007140 | male meiosis(GO:0007140) |
| 0.0 | 0.6 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.0 | 0.3 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.0 | 0.7 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.0 | 0.1 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
| 0.0 | 0.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.0 | 0.4 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.0 | 0.2 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.0 | 0.3 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.0 | 0.2 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 0.3 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.0 | 1.0 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.2 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.0 | 0.4 | GO:0009437 | carnitine metabolic process(GO:0009437) |
| 0.0 | 0.3 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 0.1 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.0 | 0.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.2 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.0 | 0.1 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.0 | 5.3 | GO:0001666 | response to hypoxia(GO:0001666) |
| 0.0 | 0.7 | GO:0006084 | acetyl-CoA metabolic process(GO:0006084) |
| 0.0 | 0.6 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.0 | 1.7 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.5 | GO:0046457 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.0 | 0.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.1 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 0.0 | 0.2 | GO:0061085 | regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.0 | 0.1 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.0 | 0.7 | GO:1903146 | regulation of mitophagy(GO:1903146) |
| 0.0 | 0.6 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.3 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
| 0.0 | 0.8 | GO:0055069 | zinc ion homeostasis(GO:0055069) |
| 0.0 | 1.3 | GO:0046323 | glucose import(GO:0046323) |
| 0.0 | 0.2 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 0.4 | GO:0031100 | organ regeneration(GO:0031100) |
| 0.0 | 0.4 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.0 | 0.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.1 | GO:1902363 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.0 | 0.3 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.0 | 0.3 | GO:1904816 | negative regulation of telomere maintenance via telomerase(GO:0032211) positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 0.0 | 0.5 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.0 | 0.5 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.4 | GO:0072112 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 0.0 | 0.2 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
| 0.0 | 0.3 | GO:0030011 | maintenance of cell polarity(GO:0030011) |
| 0.0 | 0.3 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.0 | 1.2 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.0 | 0.1 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.0 | 0.7 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 0.0 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.0 | 0.2 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.0 | 0.5 | GO:0031111 | negative regulation of microtubule polymerization or depolymerization(GO:0031111) |
| 0.0 | 0.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 6.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.5 | 2.0 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.4 | 5.3 | GO:0000796 | condensin complex(GO:0000796) |
| 0.4 | 3.3 | GO:0097413 | Lewy body(GO:0097413) |
| 0.4 | 1.1 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.3 | 1.3 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.3 | 1.4 | GO:0070442 | integrin alphaIIb-beta3 complex(GO:0070442) |
| 0.3 | 0.8 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.3 | 0.8 | GO:1990622 | CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622) |
| 0.2 | 2.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 0.9 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.2 | 1.2 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
| 0.2 | 2.6 | GO:0034464 | BBSome(GO:0034464) |
| 0.2 | 2.0 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.2 | 1.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.2 | 0.5 | GO:0090537 | CERF complex(GO:0090537) |
| 0.2 | 0.5 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.2 | 4.2 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.2 | 1.3 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.2 | 2.0 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 0.9 | GO:0031523 | Myb complex(GO:0031523) |
| 0.1 | 0.4 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.1 | 0.4 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 0.9 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 0.7 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 0.7 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 2.5 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 1.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 1.0 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 7.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 1.5 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.8 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 0.4 | GO:0000938 | GARP complex(GO:0000938) EARP complex(GO:1990745) |
| 0.1 | 0.5 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.8 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 0.9 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.4 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.1 | 0.7 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 0.6 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.1 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.3 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.1 | 1.5 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 0.2 | GO:0034774 | secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205) |
| 0.1 | 0.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 1.1 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 0.6 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 0.4 | GO:0089701 | U2AF(GO:0089701) |
| 0.1 | 1.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 0.3 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.1 | 0.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 2.0 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.8 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 0.6 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.8 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 2.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.5 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 1.1 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 0.2 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 0.0 | 0.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.4 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
| 0.0 | 0.3 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 5.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.3 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.6 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.4 | GO:0044754 | autolysosome(GO:0044754) |
| 0.0 | 0.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 4.2 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 1.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.2 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.0 | 0.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.1 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.0 | 3.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.5 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 0.7 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 2.2 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 2.9 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 9.1 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 6.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 1.2 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 1.5 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 0.3 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 0.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 0.5 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.0 | 2.1 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.2 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 0.5 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.1 | GO:1990696 | stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696) |
| 0.0 | 0.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.4 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.0 | 0.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 1.5 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.3 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.2 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 1.5 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 0.4 | GO:0030684 | preribosome(GO:0030684) |
| 0.0 | 0.6 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.3 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.8 | GO:0042602 | riboflavin reductase (NADPH) activity(GO:0042602) |
| 1.0 | 3.1 | GO:0004373 | glycogen (starch) synthase activity(GO:0004373) |
| 0.5 | 1.6 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.5 | 7.0 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.4 | 2.1 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.3 | 0.6 | GO:0055105 | ubiquitin-protein transferase inhibitor activity(GO:0055105) |
| 0.3 | 6.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.3 | 1.3 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.3 | 2.1 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.3 | 1.2 | GO:0000010 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.3 | 0.9 | GO:0030622 | U4atac snRNA binding(GO:0030622) |
| 0.3 | 2.3 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.2 | 1.2 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.2 | 1.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.2 | 1.6 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 0.9 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
| 0.2 | 1.2 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.2 | 0.8 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209) |
| 0.2 | 1.2 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.2 | 1.0 | GO:0052724 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.2 | 0.8 | GO:1990188 | euchromatin binding(GO:1990188) |
| 0.2 | 4.7 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.2 | 0.9 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.2 | 1.5 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.2 | 1.1 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.1 | 1.3 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 0.9 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.1 | 1.4 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.1 | 1.1 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 3.1 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 0.8 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 0.4 | GO:0004019 | adenylosuccinate synthase activity(GO:0004019) |
| 0.1 | 0.8 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.1 | 2.7 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 1.2 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.1 | 1.7 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 0.4 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
| 0.1 | 0.4 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 0.1 | 1.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.8 | GO:0019158 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 0.7 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.4 | GO:0003681 | bent DNA binding(GO:0003681) |
| 0.1 | 0.7 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.3 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.1 | 0.4 | GO:0050145 | cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145) |
| 0.1 | 1.1 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.1 | 2.0 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.7 | GO:0042285 | xylosyltransferase activity(GO:0042285) |
| 0.1 | 0.9 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.1 | 0.5 | GO:1990269 | RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269) |
| 0.1 | 2.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.8 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 0.7 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.4 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 0.3 | GO:2001069 | glycogen binding(GO:2001069) starch binding(GO:2001070) |
| 0.1 | 1.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.1 | 0.2 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.1 | 0.3 | GO:0052832 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
| 0.1 | 0.4 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 0.2 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.1 | 0.4 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.0 | 0.2 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.0 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.0 | 2.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 1.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.4 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.3 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.4 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.0 | 0.6 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 2.2 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.2 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.0 | 0.3 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.7 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.0 | 7.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.3 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.0 | 0.3 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.0 | 2.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.9 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.9 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.0 | 0.2 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.3 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.0 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.3 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 0.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 0.2 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.0 | 1.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.5 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 0.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 8.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.9 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 1.0 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 0.3 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 3.2 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 1.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 1.3 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.3 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 0.3 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 3.1 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 1.1 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.4 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 0.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.5 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.0 | 0.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 1.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.1 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.0 | 1.2 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.3 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.0 | 0.3 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 0.5 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 1.5 | GO:0019209 | kinase activator activity(GO:0019209) |
| 0.0 | 1.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.0 | 0.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.3 | GO:0042054 | histone methyltransferase activity(GO:0042054) |
| 0.0 | 0.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.2 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 1.1 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 2.6 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.3 | 7.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 6.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 3.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 2.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 2.5 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 6.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 2.2 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 0.2 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.9 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 3.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.6 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 1.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.5 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.8 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.2 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.1 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.0 | 0.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.5 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 0.2 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 0.5 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 0.2 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.8 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.3 | 6.4 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.2 | 4.4 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.2 | 2.0 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.2 | 2.1 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.2 | 3.3 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 1.3 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 6.4 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.1 | 1.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 0.2 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.1 | 3.9 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 9.2 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.7 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 2.3 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 3.0 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 0.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 3.8 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 0.8 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
| 0.1 | 2.1 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 1.0 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 2.7 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 1.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.4 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.6 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.8 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.5 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 1.9 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 2.2 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.8 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.6 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 2.0 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.0 | 1.1 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.3 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 0.8 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 0.4 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 1.2 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.3 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 1.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.5 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.6 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.2 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.0 | 1.0 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.2 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.2 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.5 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.3 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.5 | REACTOME RNA POL I TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
| 0.0 | 0.9 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 3.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 1.0 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.2 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.1 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |