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GSE58827: Dynamics of the Mouse Liver

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Results for Spdef

Z-value: 0.54

Motif logo

Transcription factors associated with Spdef

Gene Symbol Gene ID Gene Info
ENSMUSG00000024215.15 SAM pointed domain containing ets transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spdefmm39_v1_chr17_-_27947863_279479300.019.4e-01Click!

Activity profile of Spdef motif

Sorted Z-values of Spdef motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_65815958 1.22 ENSMUST00000119245.8
ENSMUST00000134338.8
ENSMUST00000179395.8
thyroid hormone receptor interactor 4
chr7_+_86895851 0.80 ENSMUST00000032781.14
NADPH oxidase 4
chrX_-_74886623 0.79 ENSMUST00000114057.8
plastin 3 (T-isoform)
chrX_-_74886791 0.78 ENSMUST00000137192.2
plastin 3 (T-isoform)
chr7_+_45354512 0.74 ENSMUST00000080885.12
ENSMUST00000211513.2
ENSMUST00000211357.2
D site albumin promoter binding protein
chr18_+_67338437 0.67 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr2_-_73216743 0.62 ENSMUST00000112044.8
ENSMUST00000112043.8
ENSMUST00000076463.12
G protein-coupled receptor 155
chr7_+_130633776 0.58 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr3_+_135531548 0.57 ENSMUST00000167390.8
solute carrier family 39 (metal ion transporter), member 8
chr8_+_46080746 0.56 ENSMUST00000145458.9
ENSMUST00000134321.8
sorbin and SH3 domain containing 2
chr3_-_84489783 0.55 ENSMUST00000107687.9
ENSMUST00000098990.10
ADP-ribosylation factor interacting protein 1
chr13_-_59970885 0.55 ENSMUST00000225179.2
ENSMUST00000225576.2
ENSMUST00000071703.6
terminal uridylyl transferase 7
chr9_+_117869543 0.55 ENSMUST00000044454.12
5-azacytidine induced gene 2
chr18_+_12776358 0.55 ENSMUST00000234966.2
ENSMUST00000025294.9
tetratricopeptide repeat domain 39C
chr3_-_84489923 0.54 ENSMUST00000143514.3
ADP-ribosylation factor interacting protein 1
chr16_-_87229485 0.54 ENSMUST00000039449.9
listerin E3 ubiquitin protein ligase 1
chr9_+_117869577 0.52 ENSMUST00000133580.8
5-azacytidine induced gene 2
chr3_-_5641171 0.51 ENSMUST00000071280.8
ENSMUST00000195855.6
ENSMUST00000165309.8
ENSMUST00000164828.8
peroxisomal biogenesis factor 2
chr1_+_135746330 0.51 ENSMUST00000038760.10
ladinin
chr18_-_46730547 0.51 ENSMUST00000151189.2
transmembrane p24 trafficking protein 7
chr6_-_95695781 0.51 ENSMUST00000204224.3
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr3_-_108053396 0.50 ENSMUST00000000001.5
guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr18_-_31742946 0.48 ENSMUST00000060396.7
solute carrier family 25, member 46
chr8_+_114362419 0.47 ENSMUST00000035777.10
MON1 homolog B, secretory traffciking associated
chr5_+_124577952 0.46 ENSMUST00000059580.11
lysine methyltransferase 5A
chr7_-_30672747 0.46 ENSMUST00000205961.2
lipolysis stimulated lipoprotein receptor
chr6_+_90443293 0.45 ENSMUST00000203607.2
Kruppel-like factor 15
chr2_+_83474779 0.45 ENSMUST00000081591.7
zinc finger CCCH-type containing 15
chr1_+_128171859 0.44 ENSMUST00000027592.6
UBX domain protein 4
chr3_+_135531409 0.44 ENSMUST00000180196.8
solute carrier family 39 (metal ion transporter), member 8
chr9_+_117869642 0.44 ENSMUST00000134433.8
5-azacytidine induced gene 2
chr3_-_5641295 0.44 ENSMUST00000059021.10
peroxisomal biogenesis factor 2
chr16_-_87229367 0.43 ENSMUST00000232095.2
listerin E3 ubiquitin protein ligase 1
chr9_+_80072274 0.43 ENSMUST00000035889.15
ENSMUST00000113268.8
myosin VI
chr5_+_67464284 0.42 ENSMUST00000113676.6
ENSMUST00000162372.8
solute carrier family 30 (zinc transporter), member 9
chr18_+_34994253 0.42 ENSMUST00000165033.2
early growth response 1
chr11_+_87482971 0.42 ENSMUST00000103179.10
ENSMUST00000092802.12
ENSMUST00000146871.8
myotubularin related protein 4
chr2_+_71884943 0.41 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chr2_-_12424212 0.41 ENSMUST00000124603.8
ENSMUST00000129993.3
ENSMUST00000028105.13
MINDY lysine 48 deubiquitinase 3
chr13_+_41040657 0.41 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr3_-_63872189 0.41 ENSMUST00000029402.15
solute carrier family 33 (acetyl-CoA transporter), member 1
chr9_+_80072361 0.40 ENSMUST00000184480.8
myosin VI
chr13_-_104057016 0.39 ENSMUST00000022222.12
Erbb2 interacting protein
chrX_-_106859842 0.39 ENSMUST00000120722.2
RIKEN cDNA 2610002M06 gene
chr3_-_82811269 0.39 ENSMUST00000029632.7
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
chr9_+_123358810 0.39 ENSMUST00000026270.9
ENSMUST00000239083.2
SAC1 suppressor of actin mutations 1-like (yeast)
chr10_+_58207229 0.39 ENSMUST00000238939.2
LIM and senescent cell antigen-like domains 1
chr5_-_38637474 0.38 ENSMUST00000143758.8
ENSMUST00000156272.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr15_+_35371300 0.38 ENSMUST00000048646.9
vacuolar protein sorting 13B
chr3_-_63872079 0.38 ENSMUST00000161659.8
solute carrier family 33 (acetyl-CoA transporter), member 1
chr1_-_183078488 0.38 ENSMUST00000057062.12
BRO1 domain and CAAX motif containing
chr6_-_119365632 0.38 ENSMUST00000169744.8
adiponectin receptor 2
chr8_+_114362181 0.37 ENSMUST00000179926.9
MON1 homolog B, secretory traffciking associated
chr2_+_145627900 0.37 ENSMUST00000110005.8
ENSMUST00000094480.11
Ras and Rab interactor 2
chr18_-_46730381 0.37 ENSMUST00000036030.14
transmembrane p24 trafficking protein 7
chr11_-_21522193 0.37 ENSMUST00000102874.11
ENSMUST00000238916.2
malate dehydrogenase 1, NAD (soluble)
chr1_-_84817000 0.37 ENSMUST00000186648.7
thyroid hormone receptor interactor 12
chr11_-_5492175 0.37 ENSMUST00000020776.5
coiled-coil domain containing 117
chr9_-_106353792 0.36 ENSMUST00000214682.2
ENSMUST00000112479.9
poly (ADP-ribose) polymerase family, member 3
chr8_-_84059048 0.36 ENSMUST00000177594.8
ENSMUST00000053902.4
ELMO/CED-12 domain containing 2
chr1_+_138891447 0.36 ENSMUST00000168527.8
DENN/MADD domain containing 1B
chr2_+_31462659 0.36 ENSMUST00000113482.8
far upstream element (FUSE) binding protein 3
chr4_-_4793274 0.35 ENSMUST00000084949.3
3'(2'), 5'-bisphosphate nucleotidase 2
chr5_-_146157711 0.35 ENSMUST00000169407.9
ENSMUST00000161331.8
ENSMUST00000159074.3
ENSMUST00000067837.10
ring finger protein (C3H2C3 type) 6
chr11_-_21521934 0.35 ENSMUST00000239073.2
malate dehydrogenase 1, NAD (soluble)
chr9_+_123358913 0.35 ENSMUST00000238984.2
SAC1 suppressor of actin mutations 1-like (yeast)
chr9_+_110306020 0.35 ENSMUST00000198858.5
kinesin family member 9
chrX_+_37278636 0.34 ENSMUST00000049740.3
ENSMUST00000115142.3
ENSMUST00000131124.2
zinc finger and BTB domain containing 33
chr17_-_57554631 0.34 ENSMUST00000233568.2
ENSMUST00000005975.8
G protein-coupled receptor 108
chr5_+_138083345 0.33 ENSMUST00000019660.11
ENSMUST00000066617.12
ENSMUST00000110963.8
zinc finger with KRAB and SCAN domains 1
chr9_+_110306052 0.33 ENSMUST00000197248.5
ENSMUST00000061155.12
ENSMUST00000198043.5
ENSMUST00000084952.8
kinesin family member 9
chr2_-_18397547 0.33 ENSMUST00000091418.12
ENSMUST00000166495.8
DnaJ heat shock protein family (Hsp40) member C1
chr15_+_94441486 0.32 ENSMUST00000074936.10
interleukin-1 receptor-associated kinase 4
chr5_-_146158235 0.32 ENSMUST00000161859.8
ring finger protein (C3H2C3 type) 6
chr15_+_102011352 0.32 ENSMUST00000169627.9
tensin 2
chr1_-_170042947 0.32 ENSMUST00000027979.14
ENSMUST00000123399.2
U2AF homology motif (UHM) kinase 1
chr12_+_33004178 0.32 ENSMUST00000020885.13
synaptophysin-like protein
chr15_+_102011415 0.32 ENSMUST00000046144.10
tensin 2
chr11_-_72686627 0.32 ENSMUST00000079681.6
cytochrome b5 domain containing 2
chrX_-_12628309 0.31 ENSMUST00000096495.11
ENSMUST00000076016.6
mediator complex subunit 14
chr18_-_3281089 0.31 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr11_-_48707763 0.31 ENSMUST00000140800.2
tripartite motif-containing 41
chr10_-_39775182 0.31 ENSMUST00000178045.9
ENSMUST00000178563.3
major facilitator superfamily domain containing 4B4
chr11_-_4110286 0.31 ENSMUST00000093381.11
ENSMUST00000101626.9
coiled-coil domain containing 157
chr8_+_72973560 0.30 ENSMUST00000003123.10
family with sequence similarity 32, member A
chr11_-_20062876 0.30 ENSMUST00000000137.8
ARP2 actin-related protein 2
chr13_-_74956924 0.30 ENSMUST00000223206.2
calpastatin
chr13_+_41013230 0.30 ENSMUST00000110191.10
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr11_-_105835238 0.30 ENSMUST00000019734.11
ENSMUST00000184269.3
ENSMUST00000150563.3
cytochrome b-561
chr13_-_60325170 0.29 ENSMUST00000065086.6
growth arrest specific 1
chr8_+_110505184 0.29 ENSMUST00000093157.13
adaptor protein complex AP-1, gamma 1 subunit
chr1_+_55170390 0.29 ENSMUST00000159311.8
ENSMUST00000162364.8
MOB family member 4, phocein
chr10_+_34359395 0.29 ENSMUST00000019913.15
fyn-related kinase
chr11_+_117545037 0.29 ENSMUST00000026658.13
trinucleotide repeat containing 6C
chr8_+_87350672 0.29 ENSMUST00000034141.18
ENSMUST00000122188.10
lon peptidase 2, peroxisomal
chr4_+_44756553 0.28 ENSMUST00000107824.9
zinc finger, CCHC domain containing 7
chr12_-_75642969 0.28 ENSMUST00000021447.9
ENSMUST00000220035.2
protein phosphatase 2, regulatory subunit B', epsilon
chr9_-_88320991 0.28 ENSMUST00000239462.2
ENSMUST00000165315.9
ENSMUST00000173039.9
sorting nexin 14
chr5_+_117271632 0.28 ENSMUST00000179276.8
ENSMUST00000092889.12
ENSMUST00000145640.8
TAO kinase 3
chr19_+_6096606 0.28 ENSMUST00000138532.8
ENSMUST00000129081.8
ENSMUST00000156550.8
synovial apoptosis inhibitor 1, synoviolin
chr13_-_42000958 0.27 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr15_-_36609812 0.27 ENSMUST00000226496.2
poly(A) binding protein, cytoplasmic 1
chr14_-_20596580 0.27 ENSMUST00000022355.11
ENSMUST00000161445.8
ENSMUST00000159027.8
protein phosphatase 3, catalytic subunit, beta isoform
chr14_+_53980561 0.26 ENSMUST00000103667.6
T cell receptor alpha variable 16
chr8_+_86567600 0.26 ENSMUST00000053771.14
ENSMUST00000161850.8
phosphorylase kinase beta
chr13_-_95511837 0.26 ENSMUST00000022189.9
angiogenic factor with G patch and FHA domains 1
chr1_+_151631088 0.26 ENSMUST00000188145.7
ENSMUST00000059498.12
ER degradation enhancer, mannosidase alpha-like 3
chr4_-_107780716 0.26 ENSMUST00000106719.8
ENSMUST00000106720.9
ENSMUST00000131644.2
ENSMUST00000030345.15
carnitine palmitoyltransferase 2
chr1_+_55170476 0.25 ENSMUST00000162553.2
MOB family member 4, phocein
chr4_+_140688514 0.25 ENSMUST00000010007.9
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr4_+_80828883 0.25 ENSMUST00000055922.4
leucine rich adaptor protein 1-like
chr4_+_44756608 0.25 ENSMUST00000143385.2
zinc finger, CCHC domain containing 7
chr12_-_55045887 0.25 ENSMUST00000173529.2
bromodomain adjacent to zinc finger domain 1A
chr3_+_137573436 0.25 ENSMUST00000090178.10
DnaJ heat shock protein family (Hsp40) member B14
chr5_-_38637624 0.25 ENSMUST00000067886.12
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_-_22930188 0.25 ENSMUST00000114544.10
ENSMUST00000139038.8
ENSMUST00000126112.8
ENSMUST00000178908.2
ENSMUST00000078977.14
ENSMUST00000140164.8
ENSMUST00000149719.8
abl interactor 1
chr1_+_151631203 0.25 ENSMUST00000187951.7
ENSMUST00000191070.2
ER degradation enhancer, mannosidase alpha-like 3
chr10_-_95159933 0.25 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_-_84817022 0.25 ENSMUST00000189496.7
ENSMUST00000027421.13
ENSMUST00000186894.7
thyroid hormone receptor interactor 12
chr5_-_21990170 0.25 ENSMUST00000115193.8
ENSMUST00000115192.2
ENSMUST00000115195.8
ENSMUST00000030771.12
DnaJ heat shock protein family (Hsp40) member C2
chr11_-_44361289 0.24 ENSMUST00000102795.4
ubiquitin-like domain containing CTD phosphatase 1
chr17_-_36290571 0.24 ENSMUST00000173724.2
ENSMUST00000172900.8
ENSMUST00000174849.8
proline-rich polypeptide 3
chr9_-_50657800 0.23 ENSMUST00000239417.2
ENSMUST00000034564.4
RIKEN cDNA 2310030G06 gene
chrX_+_106860083 0.23 ENSMUST00000143975.8
ENSMUST00000144695.8
ENSMUST00000167154.2
terminal nucleotidyltransferase 5D
chr19_+_57349112 0.23 ENSMUST00000036407.6
family with sequence similarity 160, member B1
chr15_-_99717956 0.23 ENSMUST00000109024.9
LIM domain and actin binding 1
chr3_+_89958940 0.23 ENSMUST00000159064.8
RIKEN cDNA 4933434E20 gene
chr8_-_86567506 0.23 ENSMUST00000034140.9
integrin alpha FG-GAP repeat containing 1
chr9_-_88320962 0.23 ENSMUST00000174806.9
sorting nexin 14
chr6_+_30509826 0.23 ENSMUST00000031797.11
serine-rich single-pass membrane protein 1
chr3_-_122778052 0.23 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr8_-_81741495 0.23 ENSMUST00000042724.8
ubiquitin specific peptidase 38
chrX_-_133177717 0.23 ENSMUST00000087541.12
ENSMUST00000087540.4
TRM2 tRNA methyltransferase 2B
chr6_+_54016543 0.23 ENSMUST00000046856.14
chimerin 2
chr17_+_85264134 0.23 ENSMUST00000112305.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr6_-_57668992 0.22 ENSMUST00000053386.6
Pigy upstream reading frame
chrX_+_36059274 0.22 ENSMUST00000016463.4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chrX_-_133177638 0.22 ENSMUST00000113252.8
TRM2 tRNA methyltransferase 2B
chr6_+_21986445 0.22 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr9_-_88320937 0.22 ENSMUST00000173011.9
sorting nexin 14
chr7_+_101027390 0.22 ENSMUST00000084895.12
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_+_44966464 0.22 ENSMUST00000114664.8
myelin protein zero-like 3
chrX_-_72759748 0.22 ENSMUST00000002091.6
B cell receptor associated protein 31
chr15_+_88703786 0.22 ENSMUST00000024042.5
cysteine-rich with EGF-like domains 2
chr13_+_22017906 0.22 ENSMUST00000180288.2
H2B clustered histone 24
chr15_-_9529898 0.22 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr7_+_143027473 0.22 ENSMUST00000052348.12
solute carrier family 22 (organic cation transporter), member 18
chr13_-_59970383 0.22 ENSMUST00000225987.2
terminal uridylyl transferase 7
chr9_+_107173907 0.22 ENSMUST00000168260.2
cytokine inducible SH2-containing protein
chr2_+_166647426 0.22 ENSMUST00000099078.10
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr7_+_27770655 0.22 ENSMUST00000138392.8
ENSMUST00000076648.8
Fc fragment of IgG binding protein
chr10_+_34359513 0.22 ENSMUST00000170771.3
fyn-related kinase
chr17_-_56312555 0.21 ENSMUST00000043785.8
signal transducing adaptor family member 2
chr16_+_94171477 0.21 ENSMUST00000117648.9
ENSMUST00000147352.8
ENSMUST00000150346.8
ENSMUST00000155692.8
ENSMUST00000153988.9
ENSMUST00000139513.9
ENSMUST00000141856.8
ENSMUST00000152117.8
ENSMUST00000150097.8
ENSMUST00000122895.8
ENSMUST00000151770.8
ENSMUST00000231569.2
ENSMUST00000147046.8
ENSMUST00000149885.8
ENSMUST00000127667.8
ENSMUST00000119131.3
ENSMUST00000145883.2
tetratricopeptide repeat domain 3
chr8_+_110505494 0.21 ENSMUST00000034171.9
adaptor protein complex AP-1, gamma 1 subunit
chr19_+_46587523 0.21 ENSMUST00000138302.9
ENSMUST00000099376.11
WW domain binding protein 1 like
chr3_-_10505113 0.21 ENSMUST00000029047.12
ENSMUST00000195822.2
ENSMUST00000099223.11
sorting nexin 16
chr15_-_76079891 0.21 ENSMUST00000023226.13
plectin
chr3_-_75464066 0.21 ENSMUST00000162138.2
ENSMUST00000029424.12
ENSMUST00000161137.8
programmed cell death 10
chr9_+_64940004 0.21 ENSMUST00000167773.2
dipeptidylpeptidase 8
chr4_+_118266582 0.21 ENSMUST00000144577.2
mediator complex subunit 8
chr1_-_43866910 0.21 ENSMUST00000153317.6
ENSMUST00000128261.2
ENSMUST00000126008.8
ENSMUST00000139451.8
UDP-glucuronate decarboxylase 1
chr17_-_26063488 0.21 ENSMUST00000176709.2
ras homolog family member T2
chr19_-_10807220 0.21 ENSMUST00000174176.3
CD6 antigen
chr11_-_83193412 0.21 ENSMUST00000176374.2
peroxisomal biogenesis factor 12
chr12_+_11316101 0.21 ENSMUST00000218866.2
structural maintenance of chromosomes 6
chr16_+_4825216 0.21 ENSMUST00000185147.8
small integral membrane protein 22
chr3_+_85946145 0.20 ENSMUST00000238331.2
SH3 domain protein D19
chr10_+_17598961 0.20 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr5_-_69749617 0.20 ENSMUST00000173927.8
ENSMUST00000120789.8
ENSMUST00000031117.13
glucosamine-6-phosphate deaminase 2
chr19_+_41017714 0.20 ENSMUST00000051806.12
ENSMUST00000112200.3
deoxynucleotidyltransferase, terminal
chr5_-_146158201 0.20 ENSMUST00000161574.8
ring finger protein (C3H2C3 type) 6
chrX_+_100298134 0.20 ENSMUST00000062000.6
forkhead box O4
chrX_+_106299484 0.20 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr9_+_64939695 0.20 ENSMUST00000034960.14
dipeptidylpeptidase 8
chr8_-_65302573 0.20 ENSMUST00000210166.2
kelch-like 2, Mayven
chr7_+_27879650 0.20 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr9_-_59260713 0.20 ENSMUST00000026265.8
Bardet-Biedl syndrome 4 (human)
chr4_+_155666933 0.20 ENSMUST00000105612.2
NAD kinase
chr9_+_65816370 0.19 ENSMUST00000206594.2
casein kinase 1, gamma 1
chr13_-_18118736 0.19 ENSMUST00000009003.9
v-ral simian leukemia viral oncogene A (ras related)
chr2_-_12424189 0.19 ENSMUST00000124515.2
MINDY lysine 48 deubiquitinase 3
chr9_-_60595401 0.19 ENSMUST00000114034.9
ENSMUST00000065603.12
leucine rich repeat containing 49
chr15_+_58805605 0.19 ENSMUST00000022980.5
NADH:ubiquinone oxidoreductase subunit B9
chr3_+_122039206 0.19 ENSMUST00000029769.14
glutamate-cysteine ligase, modifier subunit
chr19_-_10807409 0.19 ENSMUST00000080292.12
CD6 antigen
chr3_-_89300936 0.19 ENSMUST00000124783.8
ENSMUST00000126027.8
zinc finger and BTB domain containing 7B
chr8_-_123768759 0.19 ENSMUST00000098334.13
ankyrin repeat domain 11
chr9_+_65816206 0.19 ENSMUST00000205379.2
ENSMUST00000206048.2
ENSMUST00000034949.10
ENSMUST00000154589.2
casein kinase 1, gamma 1
chr19_-_59932079 0.19 ENSMUST00000171986.8
RAB11 family interacting protein 2 (class I)
chr14_-_20596508 0.19 ENSMUST00000161989.2
protein phosphatase 3, catalytic subunit, beta isoform
chr19_-_10807285 0.19 ENSMUST00000039043.15
CD6 antigen
chr2_+_3425159 0.19 ENSMUST00000100463.10
ENSMUST00000061852.12
ENSMUST00000102988.10
ENSMUST00000115066.8
DNA cross-link repair 1C
chr1_+_55170411 0.19 ENSMUST00000027122.14
MOB family member 4, phocein
chr14_-_26390986 0.19 ENSMUST00000052932.10
phosphodiesterase 12
chr18_+_30405800 0.19 ENSMUST00000115812.10
ENSMUST00000115811.8
ENSMUST00000091978.12
phosphatidylinositol 3-kinase catalytic subunit type 3
chr6_+_54794433 0.18 ENSMUST00000127331.2
zinc and ring finger 2
chr3_-_79536166 0.18 ENSMUST00000029386.14
electron transferring flavoprotein, dehydrogenase
chr11_-_83189734 0.18 ENSMUST00000108146.8
ENSMUST00000136369.2
ENSMUST00000018877.9
peroxisomal biogenesis factor 12
chr8_-_65302657 0.18 ENSMUST00000034017.9
kelch-like 2, Mayven

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 0.8 GO:0019085 early viral transcription(GO:0019085)
0.2 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.5 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 0.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.9 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.6 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 1.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.5 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.2 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 0.2 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.1 0.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.8 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:0061354 chemorepulsion of dopaminergic neuron axon(GO:0036518) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) melanocyte proliferation(GO:0097325) regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.7 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.3 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.8 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.6 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.1 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0060807 cardiogenic plate morphogenesis(GO:0003142) regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification(GO:0060807)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.7 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 1.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.0 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.3 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.2 GO:0005879 axonemal microtubule(GO:0005879) symmetric synapse(GO:0032280)
0.1 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0090537 CERF complex(GO:0090537)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0044393 microspike(GO:0044393)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0070722 Tle3-Aes complex(GO:0070722)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 2.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.5 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 0.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.1 0.6 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.4 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.2 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0051381 histamine binding(GO:0051381)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA