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GSE58827: Dynamics of the Mouse Liver
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Results for Spi1
Z-value: 3.17
Motif logo
Transcription factors associated with Spi1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
Spi1
|
ENSMUSG00000002111.9 | spleen focus forming virus (SFFV) proviral integration oncogene |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Spi1 | mm39_v1_chr2_+_90912710_90912735 | 0.90 | 4.2e-14 | Click! |
Activity profile of Spi1 motif
Sorted Z-values of Spi1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of Spi1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 19.7 | 59.1 | GO:0002149 | hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149) |
| 14.2 | 56.8 | GO:0070488 | neutrophil aggregation(GO:0070488) |
| 9.6 | 28.8 | GO:0001807 | regulation of type IV hypersensitivity(GO:0001807) |
| 8.6 | 25.7 | GO:0070947 | neutrophil mediated killing of fungus(GO:0070947) |
| 6.2 | 18.7 | GO:0051714 | regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714) |
| 6.2 | 18.6 | GO:0045660 | positive regulation of neutrophil differentiation(GO:0045660) |
| 5.4 | 16.3 | GO:0002215 | defense response to nematode(GO:0002215) |
| 5.0 | 20.2 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 4.5 | 13.6 | GO:0014805 | smooth muscle adaptation(GO:0014805) |
| 4.4 | 13.3 | GO:0002277 | myeloid dendritic cell activation involved in immune response(GO:0002277) |
| 3.7 | 3.7 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
| 3.6 | 10.8 | GO:0035702 | monocyte homeostasis(GO:0035702) |
| 3.6 | 32.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 3.6 | 7.1 | GO:0036301 | macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256) |
| 3.5 | 10.6 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 3.5 | 17.6 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 3.5 | 31.3 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 3.4 | 10.2 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
| 3.2 | 35.6 | GO:0030886 | negative regulation of myeloid dendritic cell activation(GO:0030886) |
| 3.1 | 15.4 | GO:0006742 | NADP catabolic process(GO:0006742) |
| 3.1 | 49.4 | GO:0033572 | transferrin transport(GO:0033572) |
| 3.1 | 9.2 | GO:0003330 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 3.0 | 9.1 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 3.0 | 6.1 | GO:0033624 | negative regulation of integrin activation(GO:0033624) |
| 3.0 | 6.1 | GO:2000473 | regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
| 3.0 | 12.0 | GO:0045575 | basophil activation(GO:0045575) |
| 2.9 | 22.9 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 2.8 | 11.2 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 2.8 | 66.5 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 2.7 | 2.7 | GO:0072249 | metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) |
| 2.7 | 10.7 | GO:2000449 | regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) |
| 2.6 | 5.2 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 2.6 | 15.4 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 2.6 | 10.3 | GO:0072355 | histone H3-T3 phosphorylation(GO:0072355) |
| 2.5 | 20.4 | GO:0070943 | neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) |
| 2.5 | 5.0 | GO:0002433 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
| 2.5 | 9.9 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 2.5 | 7.4 | GO:0060734 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) |
| 2.4 | 7.3 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 2.4 | 9.8 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 2.4 | 7.3 | GO:0030221 | basophil differentiation(GO:0030221) |
| 2.4 | 7.2 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 2.4 | 16.8 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
| 2.4 | 11.9 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
| 2.4 | 14.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 2.3 | 2.3 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
| 2.3 | 9.1 | GO:2001287 | negative regulation of caveolin-mediated endocytosis(GO:2001287) |
| 2.2 | 31.3 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 2.2 | 4.3 | GO:0038094 | Fc-gamma receptor signaling pathway(GO:0038094) |
| 2.1 | 10.6 | GO:1904171 | negative regulation of bleb assembly(GO:1904171) |
| 2.1 | 6.2 | GO:0002344 | peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344) |
| 2.1 | 16.5 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 2.1 | 6.2 | GO:0010138 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035) |
| 2.1 | 8.2 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 2.0 | 36.4 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
| 2.0 | 2.0 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
| 2.0 | 8.0 | GO:0001805 | type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 1.9 | 5.8 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 1.9 | 3.8 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
| 1.9 | 7.5 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 1.9 | 22.5 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 1.9 | 11.2 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 1.8 | 66.2 | GO:0045730 | respiratory burst(GO:0045730) |
| 1.8 | 1.8 | GO:1903281 | positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 1.8 | 5.3 | GO:0097045 | activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045) |
| 1.7 | 8.3 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 1.6 | 6.5 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 1.6 | 22.5 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 1.6 | 4.8 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
| 1.6 | 9.5 | GO:0006116 | NADH oxidation(GO:0006116) |
| 1.6 | 4.7 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 1.6 | 6.2 | GO:1990091 | sodium-dependent self proteolysis(GO:1990091) |
| 1.6 | 10.9 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 1.6 | 7.8 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 1.6 | 23.3 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 1.5 | 15.4 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 1.5 | 18.3 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 1.5 | 29.0 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) |
| 1.5 | 15.2 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
| 1.5 | 3.0 | GO:0050712 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
| 1.5 | 20.9 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 1.5 | 16.4 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 1.5 | 4.4 | GO:0002625 | regulation of T cell antigen processing and presentation(GO:0002625) |
| 1.5 | 7.3 | GO:1903898 | negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 1.4 | 1.4 | GO:0032066 | nucleolus to nucleoplasm transport(GO:0032066) |
| 1.4 | 1.4 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 1.4 | 7.1 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 1.4 | 5.6 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 1.4 | 19.7 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 1.4 | 5.6 | GO:0032298 | positive regulation of DNA-dependent DNA replication initiation(GO:0032298) |
| 1.4 | 2.8 | GO:0002309 | T cell proliferation involved in immune response(GO:0002309) |
| 1.4 | 6.8 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 1.4 | 10.8 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 1.3 | 4.0 | GO:0000451 | rRNA 2'-O-methylation(GO:0000451) |
| 1.3 | 11.9 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 1.3 | 9.3 | GO:1903525 | regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527) |
| 1.3 | 3.9 | GO:1903632 | positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
| 1.3 | 6.5 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 1.3 | 9.0 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 1.3 | 5.2 | GO:0035926 | chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 1.3 | 7.7 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 1.3 | 5.1 | GO:2000588 | positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588) |
| 1.3 | 3.8 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
| 1.3 | 5.1 | GO:0061534 | gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 1.3 | 2.5 | GO:0010956 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) |
| 1.3 | 3.8 | GO:1904959 | regulation of cytochrome-c oxidase activity(GO:1904959) |
| 1.2 | 5.0 | GO:0010286 | heat acclimation(GO:0010286) |
| 1.2 | 3.7 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 1.2 | 10.9 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 1.2 | 4.8 | GO:0042119 | neutrophil activation(GO:0042119) |
| 1.2 | 3.6 | GO:0019389 | glucuronoside metabolic process(GO:0019389) |
| 1.2 | 5.9 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 1.2 | 16.5 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 1.2 | 9.3 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 1.2 | 4.6 | GO:0035771 | interleukin-4-mediated signaling pathway(GO:0035771) |
| 1.1 | 5.7 | GO:0048478 | replication fork protection(GO:0048478) |
| 1.1 | 4.6 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 1.1 | 6.8 | GO:0042117 | monocyte activation(GO:0042117) |
| 1.1 | 4.6 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 1.1 | 5.7 | GO:1904976 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
| 1.1 | 3.4 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 1.1 | 8.9 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 1.1 | 5.5 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 1.1 | 5.4 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
| 1.1 | 9.6 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 1.1 | 2.1 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 1.1 | 8.5 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 1.1 | 8.5 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 1.1 | 6.3 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 1.0 | 1.0 | GO:0051542 | elastin biosynthetic process(GO:0051542) |
| 1.0 | 3.1 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 1.0 | 21.8 | GO:0072606 | interleukin-8 secretion(GO:0072606) |
| 1.0 | 3.1 | GO:0051325 | interphase(GO:0051325) mitotic interphase(GO:0051329) |
| 1.0 | 5.1 | GO:1901355 | response to rapamycin(GO:1901355) |
| 1.0 | 7.2 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 1.0 | 4.0 | GO:1900368 | regulation of RNA interference(GO:1900368) |
| 1.0 | 3.0 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
| 1.0 | 7.0 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 1.0 | 4.0 | GO:0030576 | Cajal body organization(GO:0030576) |
| 1.0 | 2.9 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
| 1.0 | 4.9 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 1.0 | 2.9 | GO:0021570 | rhombomere 4 development(GO:0021570) |
| 1.0 | 17.3 | GO:1904776 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.9 | 3.8 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.9 | 4.7 | GO:0007356 | thorax and anterior abdomen determination(GO:0007356) |
| 0.9 | 1.9 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.9 | 4.7 | GO:0002339 | B cell selection(GO:0002339) B cell negative selection(GO:0002352) |
| 0.9 | 1.9 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.9 | 2.8 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.9 | 4.6 | GO:2000418 | regulation of eosinophil migration(GO:2000416) positive regulation of eosinophil migration(GO:2000418) |
| 0.9 | 1.8 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.9 | 3.7 | GO:0002030 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) |
| 0.9 | 9.2 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.9 | 22.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.9 | 14.6 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.9 | 3.6 | GO:0032079 | positive regulation of endodeoxyribonuclease activity(GO:0032079) glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.9 | 9.0 | GO:0060315 | negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) |
| 0.9 | 17.0 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.9 | 2.7 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.9 | 1.8 | GO:1903969 | regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972) |
| 0.9 | 7.0 | GO:0061621 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.9 | 0.9 | GO:1902462 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.9 | 5.2 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.9 | 3.4 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.8 | 2.5 | GO:0042091 | interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.8 | 3.4 | GO:0009826 | unidimensional cell growth(GO:0009826) |
| 0.8 | 2.5 | GO:0036090 | cleavage furrow ingression(GO:0036090) |
| 0.8 | 5.0 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.8 | 3.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.8 | 2.4 | GO:0051659 | maintenance of mitochondrion location(GO:0051659) |
| 0.8 | 7.3 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.8 | 3.2 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.8 | 4.0 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 0.8 | 4.8 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
| 0.8 | 7.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.8 | 2.4 | GO:0002238 | response to molecule of fungal origin(GO:0002238) |
| 0.8 | 5.5 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.8 | 3.9 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.8 | 3.9 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.8 | 4.7 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.8 | 3.1 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
| 0.8 | 6.2 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.8 | 3.8 | GO:0000492 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
| 0.8 | 4.6 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.8 | 10.0 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.8 | 3.8 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.8 | 12.9 | GO:1901299 | negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299) |
| 0.8 | 4.6 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
| 0.8 | 6.8 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.8 | 12.8 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.8 | 3.8 | GO:0044849 | estrous cycle(GO:0044849) |
| 0.7 | 3.0 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.7 | 6.7 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.7 | 2.2 | GO:2000813 | negative regulation of barbed-end actin filament capping(GO:2000813) |
| 0.7 | 0.7 | GO:0071288 | cellular response to mercury ion(GO:0071288) |
| 0.7 | 5.1 | GO:0090343 | positive regulation of cell aging(GO:0090343) |
| 0.7 | 11.0 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.7 | 6.6 | GO:0045588 | positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) |
| 0.7 | 2.2 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.7 | 11.7 | GO:2000269 | regulation of fibroblast apoptotic process(GO:2000269) |
| 0.7 | 5.8 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
| 0.7 | 2.9 | GO:2000434 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.7 | 2.2 | GO:0060994 | regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) |
| 0.7 | 2.2 | GO:0034473 | U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) |
| 0.7 | 7.9 | GO:0032494 | response to peptidoglycan(GO:0032494) |
| 0.7 | 4.3 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
| 0.7 | 2.1 | GO:0035638 | patched ligand maturation(GO:0007225) signal maturation(GO:0035638) |
| 0.7 | 5.0 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.7 | 1.4 | GO:0070889 | platelet alpha granule organization(GO:0070889) |
| 0.7 | 2.8 | GO:0043096 | adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084) |
| 0.7 | 3.5 | GO:0060931 | sinoatrial node cell development(GO:0060931) |
| 0.7 | 2.1 | GO:0003294 | atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) regulation of renin secretion into blood stream(GO:1900133) |
| 0.7 | 2.1 | GO:0006427 | histidyl-tRNA aminoacylation(GO:0006427) |
| 0.7 | 4.2 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.7 | 2.8 | GO:0090004 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.7 | 0.7 | GO:0021508 | floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505) |
| 0.7 | 2.0 | GO:0006714 | sesquiterpenoid metabolic process(GO:0006714) |
| 0.7 | 3.4 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.7 | 4.0 | GO:1901228 | positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 0.7 | 12.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.7 | 7.3 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.7 | 1.3 | GO:0042891 | antibiotic transport(GO:0042891) |
| 0.7 | 6.6 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.7 | 3.9 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.7 | 5.9 | GO:0046884 | follicle-stimulating hormone secretion(GO:0046884) |
| 0.6 | 5.2 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.6 | 5.8 | GO:0021778 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.6 | 19.3 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.6 | 27.4 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.6 | 1.3 | GO:0042222 | interleukin-1 biosynthetic process(GO:0042222) |
| 0.6 | 1.9 | GO:0032685 | negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701) |
| 0.6 | 5.0 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.6 | 3.8 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.6 | 8.2 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.6 | 1.9 | GO:2000232 | regulation of rRNA processing(GO:2000232) |
| 0.6 | 0.6 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.6 | 2.5 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 0.6 | 2.5 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.6 | 0.6 | GO:0009176 | pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078) |
| 0.6 | 3.0 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.6 | 4.8 | GO:0008228 | opsonization(GO:0008228) |
| 0.6 | 4.8 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.6 | 4.2 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.6 | 4.8 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.6 | 1.8 | GO:2000118 | regulation of sodium-dependent phosphate transport(GO:2000118) |
| 0.6 | 4.7 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.6 | 3.5 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.6 | 1.8 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.6 | 5.8 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) |
| 0.6 | 29.1 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.6 | 2.3 | GO:0051140 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
| 0.6 | 1.7 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 0.6 | 1.7 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.6 | 1.7 | GO:0030472 | mitotic spindle organization in nucleus(GO:0030472) |
| 0.6 | 8.6 | GO:0045820 | negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198) |
| 0.6 | 4.0 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.6 | 4.5 | GO:1900086 | positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.6 | 6.8 | GO:0033033 | negative regulation of myeloid cell apoptotic process(GO:0033033) |
| 0.6 | 10.1 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.6 | 1.7 | GO:0040031 | snRNA modification(GO:0040031) |
| 0.6 | 4.5 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.6 | 5.0 | GO:0071474 | cellular hyperosmotic response(GO:0071474) |
| 0.6 | 2.2 | GO:0090154 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.6 | 5.0 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.5 | 1.6 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 0.5 | 3.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.5 | 1.6 | GO:0048611 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.5 | 14.1 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.5 | 2.7 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.5 | 0.5 | GO:0032741 | positive regulation of interleukin-18 production(GO:0032741) |
| 0.5 | 2.1 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.5 | 2.1 | GO:0015786 | UDP-glucose transport(GO:0015786) |
| 0.5 | 1.6 | GO:1904117 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.5 | 2.6 | GO:0052204 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.5 | 2.6 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 0.5 | 1.0 | GO:0015860 | purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642) |
| 0.5 | 2.6 | GO:0071236 | cellular response to antibiotic(GO:0071236) |
| 0.5 | 2.6 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.5 | 2.0 | GO:0050705 | regulation of interleukin-1 alpha production(GO:0032650) regulation of interleukin-1 alpha secretion(GO:0050705) |
| 0.5 | 5.1 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.5 | 2.0 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.5 | 2.0 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
| 0.5 | 35.9 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.5 | 1.5 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.5 | 2.0 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.5 | 10.0 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.5 | 4.5 | GO:0070235 | regulation of activation-induced cell death of T cells(GO:0070235) |
| 0.5 | 16.8 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.5 | 12.8 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.5 | 1.5 | GO:1902167 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167) |
| 0.5 | 0.5 | GO:0060032 | notochord regression(GO:0060032) |
| 0.5 | 2.4 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.5 | 2.9 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 0.5 | 1.5 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
| 0.5 | 5.8 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.5 | 8.7 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.5 | 1.9 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 0.5 | 3.3 | GO:0071169 | establishment of protein localization to chromatin(GO:0071169) |
| 0.5 | 3.3 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.5 | 1.4 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
| 0.5 | 2.4 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.5 | 0.5 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.5 | 1.9 | GO:0015904 | tetracycline transport(GO:0015904) |
| 0.5 | 1.9 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.5 | 9.7 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.5 | 2.3 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.5 | 4.2 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
| 0.5 | 2.3 | GO:0051572 | negative regulation of histone H3-K4 methylation(GO:0051572) |
| 0.5 | 1.4 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
| 0.5 | 9.1 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.5 | 4.1 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.5 | 8.6 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.4 | 0.9 | GO:0006296 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 0.4 | 2.7 | GO:0044838 | cell quiescence(GO:0044838) |
| 0.4 | 2.2 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.4 | 2.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.4 | 1.3 | GO:0010615 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.4 | 2.6 | GO:1903436 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.4 | 0.9 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.4 | 1.3 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.4 | 2.6 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.4 | 1.7 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
| 0.4 | 3.9 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.4 | 6.9 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.4 | 2.6 | GO:0032829 | regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) |
| 0.4 | 1.7 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.4 | 0.9 | GO:0061193 | taste bud development(GO:0061193) |
| 0.4 | 3.0 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.4 | 11.0 | GO:0048821 | erythrocyte development(GO:0048821) |
| 0.4 | 1.3 | GO:1990180 | mitochondrial tRNA 3'-end processing(GO:1990180) |
| 0.4 | 5.1 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.4 | 5.1 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.4 | 3.8 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.4 | 4.6 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.4 | 9.8 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.4 | 1.6 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.4 | 1.6 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.4 | 3.6 | GO:0002295 | T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell lineage commitment(GO:0072540) |
| 0.4 | 1.2 | GO:0015867 | ATP transport(GO:0015867) |
| 0.4 | 0.4 | GO:0030853 | negative regulation of granulocyte differentiation(GO:0030853) |
| 0.4 | 1.6 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.4 | 2.4 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
| 0.4 | 5.6 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.4 | 4.3 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.4 | 0.8 | GO:0001983 | baroreceptor response to increased systemic arterial blood pressure(GO:0001983) |
| 0.4 | 1.6 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.4 | 3.1 | GO:1901750 | peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750) |
| 0.4 | 3.9 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.4 | 3.1 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.4 | 6.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.4 | 6.1 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.4 | 0.4 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.4 | 1.1 | GO:0015827 | angiotensin-mediated drinking behavior(GO:0003051) aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827) |
| 0.4 | 3.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.4 | 0.4 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.4 | 2.3 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
| 0.4 | 6.8 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.4 | 4.9 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.4 | 6.4 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.4 | 1.5 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.4 | 0.4 | GO:0097694 | establishment of RNA localization to telomere(GO:0097694) |
| 0.4 | 31.3 | GO:0045576 | mast cell activation(GO:0045576) |
| 0.4 | 1.5 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.4 | 2.2 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.4 | 2.2 | GO:0060352 | cell adhesion molecule production(GO:0060352) |
| 0.4 | 1.4 | GO:1904579 | response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) |
| 0.4 | 3.6 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.4 | 4.2 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.4 | 15.5 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.4 | 3.9 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.3 | 4.5 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.3 | 6.6 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.3 | 2.4 | GO:0021776 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 0.3 | 3.1 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.3 | 0.7 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
| 0.3 | 3.4 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.3 | 1.4 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.3 | 4.8 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.3 | 4.8 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.3 | 5.1 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.3 | 0.7 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.3 | 3.7 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.3 | 1.7 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.3 | 1.7 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
| 0.3 | 2.7 | GO:0032202 | telomere assembly(GO:0032202) |
| 0.3 | 10.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.3 | 0.7 | GO:0001810 | regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068) |
| 0.3 | 6.3 | GO:0071173 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.3 | 0.7 | GO:0002586 | regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) |
| 0.3 | 1.0 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) spermidine catabolic process(GO:0046203) |
| 0.3 | 4.5 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.3 | 1.6 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.3 | 4.5 | GO:0046040 | IMP metabolic process(GO:0046040) |
| 0.3 | 8.6 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.3 | 1.3 | GO:0071348 | cellular response to interleukin-11(GO:0071348) |
| 0.3 | 1.3 | GO:0009816 | defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477) |
| 0.3 | 13.1 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.3 | 4.1 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.3 | 2.8 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.3 | 0.6 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.3 | 4.2 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
| 0.3 | 1.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.3 | 1.8 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.3 | 1.2 | GO:1990868 | response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107) |
| 0.3 | 1.2 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.3 | 4.4 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
| 0.3 | 3.8 | GO:0070203 | regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851) |
| 0.3 | 0.6 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.3 | 1.5 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
| 0.3 | 0.9 | GO:0034443 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) |
| 0.3 | 1.8 | GO:0019660 | glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.3 | 1.5 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.3 | 1.2 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.3 | 2.9 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.3 | 1.4 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.3 | 1.1 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.3 | 0.6 | GO:0019918 | peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) |
| 0.3 | 6.7 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.3 | 7.3 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.3 | 2.5 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.3 | 0.8 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
| 0.3 | 3.0 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.3 | 1.4 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.3 | 1.4 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.3 | 3.0 | GO:0071285 | response to lithium ion(GO:0010226) cellular response to lithium ion(GO:0071285) |
| 0.3 | 1.9 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
| 0.3 | 1.4 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.3 | 9.3 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 0.3 | 3.0 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.3 | 0.5 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.3 | 3.0 | GO:0015074 | DNA integration(GO:0015074) |
| 0.3 | 1.6 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
| 0.3 | 0.5 | GO:0042488 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) |
| 0.3 | 1.9 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.3 | 2.9 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
| 0.3 | 0.8 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.3 | 0.5 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
| 0.3 | 1.1 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.3 | 2.6 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.3 | 3.9 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.3 | 0.5 | GO:0071033 | nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
| 0.3 | 1.3 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.3 | 2.6 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.3 | 2.8 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.3 | 2.0 | GO:0060022 | hard palate development(GO:0060022) |
| 0.3 | 0.8 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.3 | 4.3 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.3 | 0.5 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 0.2 | 1.2 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.2 | 3.7 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.2 | 1.0 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.2 | 1.0 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
| 0.2 | 1.7 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.2 | 1.0 | GO:0072386 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.2 | 0.2 | GO:0046351 | disaccharide biosynthetic process(GO:0046351) |
| 0.2 | 1.5 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.2 | 2.2 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 0.2 | 3.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.2 | 1.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.2 | 5.8 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 1.2 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.2 | 0.2 | GO:0030167 | proteoglycan catabolic process(GO:0030167) |
| 0.2 | 0.7 | GO:0042539 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.2 | 5.4 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 1.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.2 | 2.3 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.2 | 1.4 | GO:0032596 | protein transport into membrane raft(GO:0032596) |
| 0.2 | 3.9 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.2 | 1.8 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
| 0.2 | 8.5 | GO:0032012 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.2 | 13.1 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.2 | 0.4 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
| 0.2 | 1.8 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.2 | 1.6 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.2 | 1.8 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.2 | 1.7 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.2 | 1.5 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.2 | 1.9 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.2 | 6.5 | GO:0006929 | substrate-dependent cell migration(GO:0006929) |
| 0.2 | 7.3 | GO:0030865 | cortical cytoskeleton organization(GO:0030865) |
| 0.2 | 16.3 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.2 | 0.2 | GO:2001200 | positive regulation of dendritic cell differentiation(GO:2001200) |
| 0.2 | 0.4 | GO:0045416 | positive regulation of interleukin-8 biosynthetic process(GO:0045416) |
| 0.2 | 0.9 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.2 | 0.8 | GO:0061188 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.2 | 0.4 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.2 | 1.0 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.2 | 0.6 | GO:0042128 | nitrate assimilation(GO:0042128) |
| 0.2 | 1.6 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.2 | 1.6 | GO:0033210 | leptin-mediated signaling pathway(GO:0033210) |
| 0.2 | 1.4 | GO:0050857 | positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) |
| 0.2 | 3.4 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.2 | 2.8 | GO:0001553 | luteinization(GO:0001553) |
| 0.2 | 2.4 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.2 | 0.4 | GO:0002579 | positive regulation of antigen processing and presentation(GO:0002579) |
| 0.2 | 0.8 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.2 | 3.9 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.2 | 0.6 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.2 | 1.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.2 | 2.2 | GO:0033628 | regulation of cell adhesion mediated by integrin(GO:0033628) |
| 0.2 | 0.7 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.2 | 6.7 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.2 | 0.6 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
| 0.2 | 2.8 | GO:0043485 | endosome to melanosome transport(GO:0035646) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
| 0.2 | 5.6 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.2 | 3.3 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.2 | 0.9 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.2 | 1.6 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.2 | 2.9 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.2 | 2.5 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.2 | 0.9 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.2 | 24.2 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.2 | 0.7 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.2 | 1.4 | GO:0090009 | primitive streak formation(GO:0090009) |
| 0.2 | 1.2 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.2 | 1.4 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.2 | 1.0 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.2 | 6.0 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.2 | 0.9 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.2 | 0.5 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.2 | 5.4 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.2 | 0.5 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.2 | 3.9 | GO:1990089 | response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.2 | 3.0 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.2 | 2.6 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.2 | 1.8 | GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254) |
| 0.2 | 0.3 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.2 | 1.4 | GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) |
| 0.2 | 0.9 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
| 0.2 | 3.8 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.2 | 1.1 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.2 | 1.4 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.2 | 0.9 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.2 | 0.6 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.2 | 0.5 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
| 0.2 | 2.3 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.2 | 0.2 | GO:0031448 | regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) |
| 0.2 | 1.5 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.2 | 2.0 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) |
| 0.2 | 0.5 | GO:2000370 | positive regulation of clathrin-mediated endocytosis(GO:2000370) |
| 0.2 | 2.6 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
| 0.2 | 6.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.2 | 1.5 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.2 | 1.1 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 0.1 | 6.6 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
| 0.1 | 0.6 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.1 | 12.4 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.1 | 2.1 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 2.4 | GO:0000305 | response to oxygen radical(GO:0000305) |
| 0.1 | 18.3 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.1 | 0.1 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.1 | 0.3 | GO:2000011 | adaxial/abaxial pattern specification(GO:0009955) regulation of adaxial/abaxial pattern formation(GO:2000011) |
| 0.1 | 0.6 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.1 | 0.7 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 0.4 | GO:0002380 | immunoglobulin secretion involved in immune response(GO:0002380) |
| 0.1 | 1.6 | GO:0090501 | RNA phosphodiester bond hydrolysis(GO:0090501) |
| 0.1 | 0.6 | GO:2000047 | regulation of cell-cell adhesion mediated by cadherin(GO:2000047) |
| 0.1 | 0.1 | GO:1904306 | positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
| 0.1 | 1.3 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 1.3 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 0.4 | GO:0031590 | C-terminal protein methylation(GO:0006481) wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
| 0.1 | 0.7 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
| 0.1 | 10.4 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
| 0.1 | 2.3 | GO:0030168 | platelet activation(GO:0030168) |
| 0.1 | 0.4 | GO:0071455 | positive regulation of integrin biosynthetic process(GO:0045726) cellular response to hyperoxia(GO:0071455) |
| 0.1 | 0.8 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393) |
| 0.1 | 3.4 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.1 | 0.4 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.1 | 0.4 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.1 | 3.0 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 1.5 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.1 | 1.3 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.1 | 0.6 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 1.5 | GO:0032096 | negative regulation of response to food(GO:0032096) |
| 0.1 | 0.2 | GO:0071873 | response to norepinephrine(GO:0071873) |
| 0.1 | 0.9 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.1 | 0.3 | GO:1903826 | mitochondrial ornithine transport(GO:0000066) L-lysine transport(GO:1902022) L-ornithine transmembrane transport(GO:1903352) L-arginine transmembrane transport(GO:1903400) L-lysine transmembrane transport(GO:1903401) arginine transmembrane transport(GO:1903826) |
| 0.1 | 1.6 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.1 | 0.3 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.1 | 1.3 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.1 | 0.6 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.1 | 8.5 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.1 | 4.1 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.1 | 0.5 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.3 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
| 0.1 | 0.5 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) |
| 0.1 | 0.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 0.9 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
| 0.1 | 0.9 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.1 | 3.9 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.1 | 1.2 | GO:0036260 | 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260) |
| 0.1 | 0.2 | GO:0045196 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 2.4 | GO:0006541 | glutamine metabolic process(GO:0006541) |
| 0.1 | 0.8 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 1.5 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.1 | 0.5 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.1 | 0.3 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.1 | 0.4 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
| 0.1 | 0.4 | GO:0098912 | membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.1 | 0.7 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.1 | 0.6 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 0.1 | 3.5 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
| 0.1 | 0.3 | GO:2000617 | positive regulation of histone H3-K9 acetylation(GO:2000617) |
| 0.1 | 1.5 | GO:0008356 | asymmetric cell division(GO:0008356) |
| 0.1 | 4.9 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.1 | 2.0 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.8 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 0.1 | 1.9 | GO:0030838 | positive regulation of actin filament polymerization(GO:0030838) |
| 0.1 | 0.7 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 4.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.9 | GO:0071380 | cellular response to prostaglandin E stimulus(GO:0071380) |
| 0.1 | 7.6 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.1 | 0.7 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 1.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 1.6 | GO:0046599 | regulation of centriole replication(GO:0046599) |
| 0.1 | 0.4 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 0.3 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.1 | 1.1 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.2 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 1.4 | GO:1903392 | negative regulation of adherens junction organization(GO:1903392) |
| 0.1 | 0.9 | GO:0014072 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 0.1 | 0.2 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.1 | 1.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.1 | 1.2 | GO:0002931 | response to ischemia(GO:0002931) |
| 0.1 | 0.6 | GO:0045631 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.1 | 0.5 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.3 | GO:0001777 | T cell homeostatic proliferation(GO:0001777) |
| 0.1 | 3.9 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.1 | 0.5 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.1 | 1.7 | GO:0070828 | heterochromatin organization(GO:0070828) |
| 0.1 | 3.3 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 0.5 | GO:0072366 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.1 | 0.4 | GO:1902177 | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177) |
| 0.1 | 0.7 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.1 | 0.7 | GO:0032485 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.1 | 0.4 | GO:2000352 | negative regulation of endothelial cell apoptotic process(GO:2000352) |
| 0.1 | 0.4 | GO:0035660 | MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660) |
| 0.1 | 1.4 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 0.7 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
| 0.1 | 0.2 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.1 | 0.5 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
| 0.1 | 0.2 | GO:0002355 | detection of tumor cell(GO:0002355) |
| 0.1 | 0.2 | GO:0042374 | phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662) |
| 0.1 | 4.2 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.1 | 0.2 | GO:0046666 | retinal cell programmed cell death(GO:0046666) |
| 0.1 | 0.2 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 0.3 | GO:0071681 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.1 | 0.4 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
| 0.1 | 0.5 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 0.4 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.1 | 2.3 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 0.3 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 0.8 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 1.1 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.1 | 0.7 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.1 | 0.8 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.1 | 4.7 | GO:0006413 | translational initiation(GO:0006413) |
| 0.1 | 1.2 | GO:0033233 | regulation of protein sumoylation(GO:0033233) |
| 0.1 | 0.5 | GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) |
| 0.1 | 0.5 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 0.2 | GO:0006393 | termination of mitochondrial transcription(GO:0006393) |
| 0.1 | 0.3 | GO:0090214 | spongiotrophoblast layer developmental growth(GO:0090214) |
| 0.1 | 0.2 | GO:0038156 | interleukin-3-mediated signaling pathway(GO:0038156) |
| 0.1 | 2.0 | GO:1901799 | negative regulation of proteasomal protein catabolic process(GO:1901799) |
| 0.1 | 1.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.4 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.0 | 0.1 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.0 | 1.0 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.0 | 0.8 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.3 | GO:0008611 | ether lipid biosynthetic process(GO:0008611) wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.0 | 0.9 | GO:0032272 | negative regulation of protein polymerization(GO:0032272) |
| 0.0 | 0.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.4 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
| 0.0 | 0.5 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.0 | 0.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 0.3 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.0 | 0.5 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.0 | 0.2 | GO:0002034 | regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) |
| 0.0 | 0.2 | GO:0043031 | negative regulation of macrophage activation(GO:0043031) |
| 0.0 | 0.3 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
| 0.0 | 1.2 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.3 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 1.8 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.1 | GO:0071469 | cellular response to alkaline pH(GO:0071469) |
| 0.0 | 11.1 | GO:0006397 | mRNA processing(GO:0006397) |
| 0.0 | 0.5 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.1 | GO:1901203 | positive regulation of extracellular matrix assembly(GO:1901203) |
| 0.0 | 0.4 | GO:0090314 | positive regulation of protein targeting to membrane(GO:0090314) |
| 0.0 | 0.1 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.0 | 0.1 | GO:0045324 | late endosome to vacuole transport(GO:0045324) late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.2 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.0 | 1.8 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 0.3 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.1 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.0 | 0.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.3 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.7 | GO:0032109 | positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109) |
| 0.0 | 0.1 | GO:0001757 | somite specification(GO:0001757) |
| 0.0 | 0.2 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.2 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
| 0.0 | 0.3 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.0 | 0.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.5 | GO:0019884 | antigen processing and presentation of exogenous antigen(GO:0019884) |
| 0.0 | 1.3 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.7 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.3 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
| 0.0 | 0.4 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.2 | GO:0060444 | branching involved in mammary gland duct morphogenesis(GO:0060444) |
| 0.0 | 0.2 | GO:0035404 | histone-serine phosphorylation(GO:0035404) |
| 0.0 | 0.2 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
| 0.0 | 0.2 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.0 | 0.6 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
| 0.0 | 0.0 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 0.0 | 0.1 | GO:0071231 | neural crest cell migration involved in heart formation(GO:0003147) folic acid metabolic process(GO:0046655) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231) |
| 0.0 | 0.0 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 0.5 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 79.8 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 5.2 | 15.6 | GO:0036398 | TCR signalosome(GO:0036398) |
| 4.6 | 4.6 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 3.4 | 58.5 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 3.2 | 9.5 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 3.0 | 9.1 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 3.0 | 9.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 2.8 | 8.5 | GO:1990031 | pinceau fiber(GO:1990031) |
| 2.6 | 7.7 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 2.6 | 28.1 | GO:0097451 | glial limiting end-foot(GO:0097451) |
| 2.6 | 10.2 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
| 2.4 | 14.6 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 2.4 | 9.6 | GO:0032127 | dense core granule membrane(GO:0032127) |
| 2.2 | 15.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 2.2 | 37.5 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 2.1 | 6.3 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 2.1 | 6.2 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 2.0 | 10.1 | GO:0044279 | other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 2.0 | 12.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 1.8 | 12.6 | GO:0097443 | sorting endosome(GO:0097443) |
| 1.8 | 15.9 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 1.8 | 23.0 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 1.7 | 5.1 | GO:0032997 | Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998) |
| 1.6 | 6.4 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 1.5 | 10.7 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 1.5 | 11.9 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.5 | 5.9 | GO:0036284 | tubulobulbar complex(GO:0036284) |
| 1.4 | 5.7 | GO:0033597 | mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298) |
| 1.4 | 8.4 | GO:0097149 | centralspindlin complex(GO:0097149) |
| 1.4 | 4.2 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 1.4 | 8.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 1.4 | 11.0 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 1.4 | 2.7 | GO:0005608 | laminin-3 complex(GO:0005608) |
| 1.4 | 13.5 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 1.3 | 6.6 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 1.3 | 3.9 | GO:0034066 | RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066) |
| 1.3 | 6.4 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 1.3 | 19.0 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 1.2 | 87.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 1.2 | 1.2 | GO:1990357 | terminal web(GO:1990357) |
| 1.2 | 2.4 | GO:0031673 | H zone(GO:0031673) |
| 1.2 | 39.9 | GO:0001891 | phagocytic cup(GO:0001891) |
| 1.2 | 10.9 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 1.2 | 14.5 | GO:0000801 | central element(GO:0000801) |
| 1.2 | 11.8 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 1.2 | 5.8 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
| 1.1 | 3.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 1.1 | 9.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 1.1 | 9.7 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 1.1 | 4.3 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 1.1 | 5.3 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 1.1 | 6.3 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 1.0 | 18.5 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 1.0 | 2.1 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 1.0 | 11.8 | GO:0008278 | cohesin complex(GO:0008278) |
| 1.0 | 3.9 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 1.0 | 2.9 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.9 | 6.5 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.9 | 2.7 | GO:0070992 | translation initiation complex(GO:0070992) |
| 0.9 | 3.5 | GO:0008623 | CHRAC(GO:0008623) |
| 0.9 | 2.6 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.9 | 8.8 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.9 | 8.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.9 | 35.6 | GO:0008305 | integrin complex(GO:0008305) |
| 0.9 | 8.7 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.9 | 2.6 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.8 | 5.1 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.8 | 4.1 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.8 | 15.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.8 | 2.4 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.8 | 1.6 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.8 | 3.9 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.8 | 3.9 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.7 | 36.7 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.7 | 3.7 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.7 | 6.5 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.7 | 11.5 | GO:0042555 | MCM complex(GO:0042555) |
| 0.7 | 6.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.7 | 35.0 | GO:0002102 | podosome(GO:0002102) |
| 0.7 | 53.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.6 | 3.2 | GO:0061673 | mitotic spindle astral microtubule(GO:0061673) |
| 0.6 | 1.9 | GO:0097144 | BAX complex(GO:0097144) |
| 0.6 | 3.8 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.6 | 4.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.6 | 3.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.6 | 5.4 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.6 | 1.8 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.6 | 3.5 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.6 | 6.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.6 | 4.5 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.6 | 13.4 | GO:0033202 | DNA helicase complex(GO:0033202) |
| 0.6 | 16.1 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.5 | 6.0 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.5 | 3.8 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 0.5 | 3.7 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.5 | 3.7 | GO:0005638 | lamin filament(GO:0005638) |
| 0.5 | 2.1 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.5 | 3.6 | GO:0036396 | MIS complex(GO:0036396) |
| 0.5 | 2.5 | GO:0098890 | extrinsic component of postsynaptic membrane(GO:0098890) |
| 0.5 | 10.1 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.5 | 2.5 | GO:0070938 | contractile ring(GO:0070938) |
| 0.5 | 27.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.5 | 1.5 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.5 | 13.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.5 | 3.7 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.5 | 6.8 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.4 | 0.9 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.4 | 2.6 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.4 | 2.9 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.4 | 16.2 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.4 | 1.2 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.4 | 2.4 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.4 | 9.7 | GO:0000145 | exocyst(GO:0000145) |
| 0.4 | 7.2 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.4 | 5.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.4 | 1.9 | GO:0043219 | lateral loop(GO:0043219) |
| 0.4 | 9.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.4 | 10.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.4 | 2.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.4 | 4.0 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.4 | 16.8 | GO:0031430 | M band(GO:0031430) |
| 0.4 | 15.3 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.4 | 3.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.4 | 4.6 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 0.4 | 2.8 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.4 | 1.4 | GO:0032021 | NELF complex(GO:0032021) |
| 0.4 | 4.9 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.4 | 5.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.4 | 1.1 | GO:0005607 | laminin-2 complex(GO:0005607) |
| 0.3 | 6.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.3 | 0.7 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.3 | 5.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.3 | 2.0 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.3 | 0.7 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.3 | 1.6 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.3 | 1.3 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.3 | 9.3 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.3 | 1.3 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.3 | 1.6 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.3 | 1.9 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.3 | 5.9 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.3 | 0.9 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.3 | 4.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.3 | 0.9 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.3 | 1.7 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
| 0.3 | 2.3 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.3 | 4.0 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.3 | 0.6 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.3 | 3.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.3 | 1.7 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.3 | 2.8 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.3 | 3.6 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.3 | 0.8 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.3 | 0.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.3 | 2.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.3 | 1.3 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.3 | 1.6 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.3 | 2.1 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
| 0.3 | 2.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.3 | 2.8 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.3 | 1.8 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
| 0.2 | 1.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.2 | 1.5 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.2 | 0.7 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.2 | 0.5 | GO:0032545 | CURI complex(GO:0032545) UTP-C complex(GO:0034456) |
| 0.2 | 1.7 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.2 | 0.5 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.2 | 2.4 | GO:0032009 | early phagosome(GO:0032009) |
| 0.2 | 1.6 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 3.2 | GO:0090543 | Flemming body(GO:0090543) |
| 0.2 | 1.4 | GO:0031523 | Myb complex(GO:0031523) |
| 0.2 | 35.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.2 | 3.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.2 | 3.8 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.2 | 6.1 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 0.5 | GO:0020016 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.2 | 0.7 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.2 | 1.5 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.2 | 4.0 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 2.0 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 0.2 | 3.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 2.2 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.2 | 3.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.2 | 0.6 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
| 0.2 | 6.9 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.2 | 6.6 | GO:0016592 | mediator complex(GO:0016592) |
| 0.2 | 2.1 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.2 | 5.0 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.2 | 28.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.2 | 13.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 2.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.2 | 1.2 | GO:0033503 | HULC complex(GO:0033503) |
| 0.2 | 2.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.2 | 15.0 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.2 | 1.1 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.2 | 16.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 1.3 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.2 | 3.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.2 | 2.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.2 | 2.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.2 | 2.8 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.2 | 3.0 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.2 | 1.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 3.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 1.0 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 0.5 | GO:0005760 | gamma DNA polymerase complex(GO:0005760) |
| 0.2 | 3.0 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.2 | 2.5 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.2 | 10.7 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.2 | 0.5 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.2 | 1.1 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.2 | 2.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.2 | 27.4 | GO:0001726 | ruffle(GO:0001726) |
| 0.2 | 0.8 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.2 | 4.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.2 | 0.5 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.2 | 19.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 3.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 0.6 | GO:0071942 | XPC complex(GO:0071942) |
| 0.1 | 1.0 | GO:0070187 | telosome(GO:0070187) |
| 0.1 | 4.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 2.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.4 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.1 | 1.5 | GO:0005845 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.1 | 2.5 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 10.2 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.1 | 1.0 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 3.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 3.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 3.5 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 0.4 | GO:0002095 | caveolar macromolecular signaling complex(GO:0002095) |
| 0.1 | 1.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 6.0 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.1 | 2.2 | GO:0032155 | cell division site(GO:0032153) cell division site part(GO:0032155) |
| 0.1 | 0.9 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.1 | 2.4 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 3.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 1.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 4.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.3 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 1.8 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 2.7 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 17.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 13.3 | GO:0019814 | immunoglobulin complex(GO:0019814) |
| 0.1 | 1.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.3 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.1 | 0.9 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.3 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 0.1 | 1.2 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 3.7 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 0.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 5.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 6.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 3.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 3.2 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 22.2 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 0.4 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 0.6 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.1 | 2.7 | GO:0005657 | replication fork(GO:0005657) |
| 0.1 | 2.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 0.4 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.1 | 1.0 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.6 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 3.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 1.2 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 1.0 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 5.9 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 6.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 11.4 | GO:0005819 | spindle(GO:0005819) |
| 0.1 | 0.7 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 7.9 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 3.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.5 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.1 | 8.0 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 0.2 | GO:0036501 | UFD1-NPL4 complex(GO:0036501) |
| 0.1 | 0.3 | GO:0070449 | elongin complex(GO:0070449) |
| 0.1 | 1.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 0.7 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.1 | 0.5 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 1.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 0.6 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 3.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.1 | 2.4 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.1 | 0.9 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 1.5 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.1 | 1.6 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 1.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 2.9 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.1 | 2.3 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 14.9 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 0.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.1 | 0.2 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.5 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.5 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 2.4 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 2.9 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.5 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 0.3 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 0.2 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.0 | 2.1 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.1 | GO:0090537 | CERF complex(GO:0090537) |
| 0.0 | 5.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.1 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.3 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.1 | GO:0036157 | outer dynein arm(GO:0036157) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.3 | 73.0 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 7.2 | 36.2 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 6.8 | 27.3 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 5.9 | 23.6 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 5.4 | 70.8 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 4.2 | 21.0 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 3.8 | 11.3 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 3.6 | 32.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 3.4 | 10.3 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
| 3.4 | 13.7 | GO:0032093 | SAM domain binding(GO:0032093) |
| 3.3 | 9.8 | GO:0004686 | elongation factor-2 kinase activity(GO:0004686) |
| 2.8 | 33.3 | GO:0008061 | chitin binding(GO:0008061) |
| 2.7 | 8.1 | GO:0035717 | chemokine (C-C motif) ligand 7 binding(GO:0035717) |
| 2.5 | 20.3 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 2.4 | 14.7 | GO:0016019 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019) |
| 2.4 | 7.2 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 2.3 | 9.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 2.2 | 6.7 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
| 2.2 | 6.5 | GO:0044715 | 8-oxo-dGDP phosphatase activity(GO:0044715) |
| 2.0 | 2.0 | GO:0031433 | telethonin binding(GO:0031433) |
| 2.0 | 14.2 | GO:0015265 | urea channel activity(GO:0015265) |
| 2.0 | 5.9 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 1.9 | 9.5 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 1.9 | 18.9 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 1.9 | 5.6 | GO:0004132 | dCMP deaminase activity(GO:0004132) |
| 1.9 | 14.9 | GO:0051425 | PTB domain binding(GO:0051425) |
| 1.8 | 5.5 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
| 1.8 | 5.5 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 1.8 | 5.4 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 1.8 | 5.3 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 1.8 | 7.0 | GO:0031720 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
| 1.6 | 6.5 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 1.6 | 3.2 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 1.6 | 6.4 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 1.6 | 6.3 | GO:0050309 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 1.6 | 4.7 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 1.5 | 16.9 | GO:0033691 | sialic acid binding(GO:0033691) |
| 1.5 | 88.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 1.5 | 15.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 1.5 | 1.5 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 1.5 | 4.4 | GO:0004088 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 1.4 | 8.6 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 1.4 | 6.9 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 1.3 | 4.0 | GO:0070039 | rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039) |
| 1.2 | 6.2 | GO:0019767 | IgE receptor activity(GO:0019767) |
| 1.2 | 4.9 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 1.2 | 11.0 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 1.2 | 3.6 | GO:0019959 | interleukin-8 binding(GO:0019959) |
| 1.2 | 5.9 | GO:0004974 | leukotriene receptor activity(GO:0004974) |
| 1.2 | 5.8 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 1.1 | 4.6 | GO:0031493 | nucleosomal histone binding(GO:0031493) |
| 1.1 | 14.7 | GO:0052813 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 1.1 | 12.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 1.1 | 5.5 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 1.1 | 20.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 1.1 | 6.3 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 1.0 | 3.1 | GO:0070138 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
| 1.0 | 18.0 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 1.0 | 41.7 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 1.0 | 8.9 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 1.0 | 6.9 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 1.0 | 14.5 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.9 | 7.6 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.9 | 2.8 | GO:0003999 | adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999) |
| 0.9 | 15.1 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.9 | 1.8 | GO:0035197 | siRNA binding(GO:0035197) |
| 0.9 | 4.6 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.9 | 2.7 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.9 | 8.2 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.9 | 9.0 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.9 | 2.7 | GO:0009383 | rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) |
| 0.9 | 5.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.9 | 1.8 | GO:0042497 | triacyl lipopeptide binding(GO:0042497) |
| 0.9 | 6.2 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.9 | 2.6 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.9 | 58.0 | GO:0004601 | peroxidase activity(GO:0004601) |
| 0.9 | 9.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.9 | 12.9 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.9 | 6.0 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.8 | 8.5 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.8 | 5.1 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.8 | 3.4 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.8 | 2.5 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.8 | 3.3 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.8 | 5.0 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.8 | 3.3 | GO:0071553 | uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553) |
| 0.8 | 4.9 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.8 | 5.5 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.8 | 8.7 | GO:0004908 | interleukin-1 receptor activity(GO:0004908) |
| 0.8 | 3.8 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.8 | 6.1 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.8 | 33.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.8 | 3.0 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.7 | 4.5 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.7 | 2.2 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.7 | 7.4 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.7 | 7.4 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.7 | 5.9 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.7 | 2.2 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.7 | 2.2 | GO:0019002 | GMP binding(GO:0019002) |
| 0.7 | 2.2 | GO:0001132 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
| 0.7 | 7.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.7 | 4.3 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.7 | 3.5 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
| 0.7 | 2.8 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.7 | 2.1 | GO:0004821 | histidine-tRNA ligase activity(GO:0004821) |
| 0.7 | 6.3 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.7 | 7.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.7 | 9.5 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.7 | 3.4 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.7 | 4.7 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.7 | 11.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.7 | 37.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.6 | 1.9 | GO:0016426 | tRNA (adenine) methyltransferase activity(GO:0016426) |
| 0.6 | 4.5 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.6 | 2.6 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.6 | 10.1 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.6 | 4.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.6 | 9.4 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.6 | 3.7 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.6 | 5.0 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.6 | 3.7 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 0.6 | 1.8 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 0.6 | 1.8 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.6 | 15.6 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
| 0.6 | 7.8 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.6 | 1.8 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.6 | 2.4 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.6 | 12.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.6 | 1.8 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.6 | 4.1 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.6 | 0.6 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.6 | 2.4 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.6 | 2.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.6 | 13.9 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.6 | 2.9 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
| 0.6 | 19.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.6 | 30.3 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.6 | 14.5 | GO:0042171 | lysophosphatidic acid acyltransferase activity(GO:0042171) |
| 0.6 | 2.8 | GO:0102344 | 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345) |
| 0.5 | 3.3 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.5 | 1.6 | GO:0050785 | advanced glycation end-product receptor activity(GO:0050785) |
| 0.5 | 11.7 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.5 | 3.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.5 | 2.1 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 0.5 | 55.8 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.5 | 6.8 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.5 | 7.3 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.5 | 5.7 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.5 | 2.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.5 | 3.6 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
| 0.5 | 1.5 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.5 | 1.5 | GO:0004420 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.5 | 2.0 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.5 | 2.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.5 | 4.9 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.5 | 4.4 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.5 | 8.2 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.5 | 2.4 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.5 | 18.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.5 | 1.9 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.5 | 1.9 | GO:0008493 | tetracycline transporter activity(GO:0008493) |
| 0.5 | 5.1 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.5 | 0.9 | GO:0030622 | U4atac snRNA binding(GO:0030622) |
| 0.5 | 4.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.5 | 3.7 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.5 | 1.8 | GO:0051435 | BH4 domain binding(GO:0051435) |
| 0.5 | 2.3 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.4 | 22.5 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.4 | 6.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.4 | 3.6 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.4 | 1.3 | GO:0001096 | TFIIF-class transcription factor binding(GO:0001096) |
| 0.4 | 11.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.4 | 1.3 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
| 0.4 | 32.8 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.4 | 2.6 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.4 | 3.4 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.4 | 3.4 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.4 | 2.1 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.4 | 4.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.4 | 1.7 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.4 | 2.1 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.4 | 1.2 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
| 0.4 | 8.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.4 | 1.2 | GO:0018169 | ribosomal S6-glutamic acid ligase activity(GO:0018169) |
| 0.4 | 1.2 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.4 | 6.1 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.4 | 6.0 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.4 | 3.2 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.4 | 2.8 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.4 | 1.6 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.4 | 2.8 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.4 | 3.9 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.4 | 1.6 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.4 | 1.9 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.4 | 1.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.4 | 6.9 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.4 | 14.5 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.4 | 2.7 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.4 | 4.9 | GO:0001054 | RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055) |
| 0.4 | 3.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.4 | 4.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.4 | 1.9 | GO:0070538 | oleic acid binding(GO:0070538) |
| 0.4 | 5.9 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.4 | 1.8 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.4 | 1.8 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.4 | 6.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.3 | 4.5 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.3 | 1.4 | GO:0070976 | TIR domain binding(GO:0070976) |
| 0.3 | 23.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.3 | 3.8 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.3 | 2.0 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.3 | 3.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.3 | 1.3 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
| 0.3 | 14.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.3 | 30.7 | GO:0001190 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.3 | 2.6 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.3 | 3.6 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.3 | 3.2 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.3 | 1.6 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.3 | 22.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.3 | 2.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.3 | 0.6 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) |
| 0.3 | 7.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.3 | 35.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.3 | 1.5 | GO:0019976 | interleukin-2 binding(GO:0019976) |
| 0.3 | 8.6 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.3 | 3.9 | GO:1990446 | snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446) |
| 0.3 | 1.2 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
| 0.3 | 2.1 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.3 | 1.8 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.3 | 2.1 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.3 | 9.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.3 | 1.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.3 | 1.2 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.3 | 1.7 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
| 0.3 | 2.6 | GO:1903136 | cuprous ion binding(GO:1903136) |
| 0.3 | 13.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.3 | 2.0 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.3 | 9.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.3 | 0.9 | GO:0005167 | neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKB receptor binding(GO:0005169) |
| 0.3 | 4.2 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.3 | 8.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.3 | 2.0 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.3 | 0.6 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.3 | 16.5 | GO:0019209 | kinase activator activity(GO:0019209) |
| 0.3 | 11.9 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.3 | 11.6 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.3 | 1.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.3 | 1.4 | GO:0089720 | caspase binding(GO:0089720) |
| 0.3 | 1.1 | GO:0008386 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) |
| 0.3 | 2.7 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.3 | 1.6 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.3 | 18.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.3 | 2.1 | GO:0015197 | peptide transporter activity(GO:0015197) |
| 0.3 | 16.5 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.3 | 32.5 | GO:0005178 | integrin binding(GO:0005178) |
| 0.3 | 1.1 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.3 | 1.3 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.3 | 1.0 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.3 | 1.8 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.3 | 3.1 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.3 | 5.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.3 | 2.8 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.3 | 1.0 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.2 | 3.5 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.2 | 1.0 | GO:0032558 | adenyl deoxyribonucleotide binding(GO:0032558) |
| 0.2 | 4.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 30.9 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.2 | 2.2 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.2 | 1.0 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.2 | 0.7 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.2 | 4.1 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.2 | 4.7 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 1.2 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.2 | 1.6 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 5.1 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.2 | 0.9 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.2 | 6.9 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.2 | 1.6 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.2 | 2.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.2 | 1.8 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.2 | 3.7 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.2 | 0.8 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.2 | 3.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.2 | 0.4 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 4.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.2 | 1.0 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.2 | 31.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.2 | 1.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.2 | 0.6 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.2 | 0.8 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 0.2 | 1.8 | GO:0022821 | potassium ion antiporter activity(GO:0022821) |
| 0.2 | 1.0 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.2 | 0.8 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.2 | 0.8 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 0.2 | 8.0 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.2 | 70.4 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.2 | 3.8 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.2 | 1.5 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 2.3 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.2 | 2.4 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.2 | 0.7 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.2 | 1.8 | GO:0004536 | deoxyribonuclease activity(GO:0004536) |
| 0.2 | 9.1 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.2 | 6.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.2 | 0.9 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.2 | 0.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.2 | 2.2 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
| 0.2 | 1.8 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.2 | 0.7 | GO:0035827 | rubidium ion transmembrane transporter activity(GO:0035827) |
| 0.2 | 0.9 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 1.0 | GO:0019961 | interferon binding(GO:0019961) |
| 0.2 | 1.0 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.2 | 1.4 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 1.4 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.2 | 2.6 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.2 | 1.2 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
| 0.2 | 2.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.2 | 3.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 0.5 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 0.2 | 0.5 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.2 | 1.0 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.2 | 1.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.2 | 2.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.2 | 7.0 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.2 | 3.8 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.2 | 2.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.2 | 2.6 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.2 | 4.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 4.3 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.2 | 13.2 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.2 | 2.5 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 1.4 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.2 | 0.9 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.1 | 9.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 5.0 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.1 | 4.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 0.7 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.1 | 0.8 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 1.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 0.8 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 1.0 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 5.3 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 0.8 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 0.8 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.1 | 0.9 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 0.6 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.1 | 2.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.8 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 3.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 1.2 | GO:0004445 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030) |
| 0.1 | 0.3 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 1.0 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.1 | 0.3 | GO:0004958 | prostaglandin F receptor activity(GO:0004958) |
| 0.1 | 7.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 0.3 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.1 | 5.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 0.2 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.1 | 0.6 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.1 | 3.7 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 5.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 1.5 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.3 | GO:0030943 | mitochondrion targeting sequence binding(GO:0030943) |
| 0.1 | 2.0 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 1.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 1.1 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 55.4 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 15.0 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 0.9 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
| 0.1 | 4.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 0.5 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 1.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.5 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 1.3 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.1 | 2.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 4.7 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 1.0 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.1 | 2.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.5 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 0.2 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 1.7 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.4 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.1 | 2.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.4 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.1 | 0.8 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 0.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.8 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.1 | 0.1 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.1 | 0.4 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.1 | 1.4 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 1.0 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.1 | 0.4 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.1 | 0.4 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.1 | 2.1 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 3.0 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 0.2 | GO:0005174 | CD40 receptor binding(GO:0005174) |
| 0.1 | 1.0 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.5 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.1 | 0.7 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 1.0 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.1 | 0.2 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.1 | 1.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 6.5 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.1 | 0.5 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 1.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 1.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.2 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 0.7 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.1 | 0.9 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.5 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 0.5 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.5 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.1 | 0.2 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.1 | 0.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 0.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 0.3 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.1 | 1.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 1.6 | GO:0043175 | RNA polymerase core enzyme binding(GO:0043175) |
| 0.1 | 12.3 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 2.0 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.1 | 1.1 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 3.5 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.1 | 0.2 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) interleukin-3 binding(GO:0019978) |
| 0.1 | 0.5 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.1 | 3.2 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 0.3 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.6 | GO:0005372 | water transmembrane transporter activity(GO:0005372) |
| 0.0 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 1.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.9 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.0 | 0.3 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.0 | 0.4 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.0 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 1.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.1 | GO:0052723 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.0 | 1.6 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.3 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.0 | 0.1 | GO:0034191 | apolipoprotein A-I receptor binding(GO:0034191) |
| 0.0 | 0.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 1.5 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 3.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.3 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.2 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.0 | 0.7 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.1 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 0.0 | 3.2 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.2 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.0 | 0.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 0.5 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.1 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.0 | 0.1 | GO:0097604 | temperature-gated cation channel activity(GO:0097604) |
| 0.0 | 0.1 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.0 | 0.5 | GO:0034062 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
| 0.0 | 2.4 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 8.3 | GO:0003712 | transcription cofactor activity(GO:0003712) |
| 0.0 | 0.1 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) hemi-methylated DNA-binding(GO:0044729) |
| 0.0 | 0.4 | GO:0016595 | glutamate binding(GO:0016595) |
| 0.0 | 0.2 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.2 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 0.1 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.0 | 0.4 | GO:0005351 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.0 | 0.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 1.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.4 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 0.4 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.2 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.0 | 0.1 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.0 | 0.1 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 0.3 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.1 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.0 | 11.4 | GO:0003723 | RNA binding(GO:0003723) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 29.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 1.7 | 40.9 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 1.2 | 20.6 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 1.2 | 42.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 1.1 | 53.9 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 1.1 | 81.6 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 1.1 | 7.7 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 1.0 | 38.5 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 1.0 | 17.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 1.0 | 17.2 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 1.0 | 13.9 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.9 | 26.3 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.9 | 68.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.8 | 11.5 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.8 | 54.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.8 | 46.8 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.7 | 18.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.7 | 20.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.7 | 24.7 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.7 | 67.5 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.6 | 6.2 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.6 | 13.8 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.6 | 19.5 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.6 | 14.0 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.5 | 55.9 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.5 | 12.4 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.5 | 14.5 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.5 | 37.2 | PID E2F PATHWAY | E2F transcription factor network |
| 0.5 | 10.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.5 | 8.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.5 | 12.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.5 | 10.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.4 | 20.5 | PID ATR PATHWAY | ATR signaling pathway |
| 0.4 | 9.6 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.4 | 9.0 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.4 | 4.5 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.4 | 30.2 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.4 | 25.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.3 | 14.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.3 | 2.7 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.3 | 4.2 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.3 | 12.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.3 | 14.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.3 | 4.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.3 | 7.6 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.3 | 7.2 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.3 | 17.7 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.3 | 13.6 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.3 | 2.3 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.2 | 9.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.2 | 4.0 | PID FOXO PATHWAY | FoxO family signaling |
| 0.2 | 4.2 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.2 | 2.8 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 10.7 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.2 | 7.5 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.2 | 3.7 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.2 | 7.9 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.2 | 2.7 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.2 | 6.4 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.2 | 3.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.2 | 3.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.2 | 1.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.2 | 22.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.2 | 5.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.2 | 10.8 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.2 | 1.0 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.2 | 4.3 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 6.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.2 | 7.8 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 1.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 1.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 0.9 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 2.2 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 3.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 3.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 1.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 1.3 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 1.2 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 2.4 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 7.3 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 0.7 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 3.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 1.5 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 15.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 1.8 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 1.7 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.4 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 2.6 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 4.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 0.7 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.5 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.5 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.5 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.7 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 1.1 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.2 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 0.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.7 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.5 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.1 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.4 | 37.6 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 2.4 | 52.7 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 2.0 | 98.8 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 1.8 | 10.7 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 1.5 | 97.5 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 1.5 | 23.0 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 1.4 | 19.0 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 1.3 | 9.3 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 1.3 | 16.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 1.3 | 20.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.3 | 34.5 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 1.0 | 3.0 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 1.0 | 52.4 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 1.0 | 20.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.9 | 14.8 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.9 | 9.8 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.8 | 36.9 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.8 | 5.0 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.8 | 1.6 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.8 | 46.7 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.8 | 38.9 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.7 | 31.2 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.7 | 5.2 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.7 | 5.1 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.7 | 9.3 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.7 | 83.9 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.7 | 11.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.7 | 23.7 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.7 | 13.5 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.7 | 6.0 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.6 | 10.6 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.6 | 2.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.6 | 2.3 | REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | Genes involved in SCF-beta-TrCP mediated degradation of Emi1 |
| 0.6 | 8.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.6 | 9.5 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.6 | 14.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.6 | 27.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.5 | 28.8 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.5 | 6.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.5 | 9.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.5 | 5.0 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.5 | 7.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.5 | 10.5 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.5 | 9.5 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.5 | 6.5 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.5 | 12.9 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.5 | 12.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.4 | 10.8 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.4 | 4.9 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.4 | 12.0 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.4 | 1.3 | REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 0.4 | 7.3 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.4 | 2.6 | REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.4 | 12.8 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.4 | 9.0 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.4 | 2.7 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.4 | 35.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.4 | 3.3 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.4 | 7.5 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.3 | 37.1 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.3 | 11.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.3 | 15.3 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.3 | 14.2 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.3 | 7.2 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.3 | 5.0 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.3 | 4.8 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.3 | 10.1 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.3 | 3.1 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.3 | 6.4 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.3 | 24.1 | REACTOME G ALPHA1213 SIGNALLING EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.3 | 3.8 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.2 | 5.4 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 2.9 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 7.2 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.2 | 2.1 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.2 | 3.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.2 | 3.0 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.2 | 29.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.2 | 1.4 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.2 | 2.2 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.2 | 5.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.2 | 3.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.2 | 4.6 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.2 | 5.6 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.2 | 1.1 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.2 | 2.9 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.2 | 0.7 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.2 | 3.1 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.2 | 9.9 | REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.2 | 7.9 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 2.0 | REACTOME ER PHAGOSOME PATHWAY | Genes involved in ER-Phagosome pathway |
| 0.2 | 5.5 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 5.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.7 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.1 | 3.6 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.1 | 2.8 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 17.1 | REACTOME INTERFERON SIGNALING | Genes involved in Interferon Signaling |
| 0.1 | 2.1 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 15.2 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 0.4 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 2.2 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 0.9 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.1 | 0.8 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.1 | 3.4 | REACTOME TCR SIGNALING | Genes involved in TCR signaling |
| 0.1 | 2.8 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 1.6 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 2.3 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 8.7 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 1.9 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 2.8 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 0.8 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.1 | 1.1 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 5.6 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 1.6 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.1 | 0.5 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 0.8 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 0.6 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.1 | 3.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.8 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.1 | 3.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.6 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 1.1 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 5.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 0.6 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 0.9 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 2.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.3 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.0 | 0.3 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 0.3 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 1.0 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.5 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.2 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.3 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 1.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.8 | REACTOME PI3K EVENTS IN ERBB4 SIGNALING | Genes involved in PI3K events in ERBB4 signaling |
| 0.0 | 0.9 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 1.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.1 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.1 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.0 | 0.2 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |