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GSE58827: Dynamics of the Mouse Liver

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Results for Stat2

Z-value: 1.59

Motif logo

Transcription factors associated with Stat2

Gene Symbol Gene ID Gene Info
ENSMUSG00000040033.17 signal transducer and activator of transcription 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat2mm39_v1_chr10_+_128106414_1281064460.806.1e-09Click!

Activity profile of Stat2 motif

Sorted Z-values of Stat2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41498716 11.84 ENSMUST00000070380.5
protease, serine 2
chr19_+_3372296 9.04 ENSMUST00000237938.2
carnitine palmitoyltransferase 1a, liver
chr16_+_36041838 6.58 ENSMUST00000187183.7
ENSMUST00000187742.7
cystatin A family member 2
chr12_+_104372962 6.57 ENSMUST00000021506.6
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr12_-_26506422 5.80 ENSMUST00000020970.10
radical S-adenosyl methionine domain containing 2
chr18_+_60515755 5.70 ENSMUST00000237185.2
interferon inducible GTPase 1
chr14_+_40827108 5.46 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr19_+_34560922 5.37 ENSMUST00000102825.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_48883053 5.29 ENSMUST00000059930.3
ENSMUST00000068063.4
predicted gene 12185
T cell specific GTPase 1
chr6_+_121222865 5.19 ENSMUST00000032198.11
ubiquitin specific peptidase 18
chr11_-_83421333 5.05 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr14_+_78141679 4.35 ENSMUST00000022591.16
ENSMUST00000169978.2
ENSMUST00000227903.2
epithelial stromal interaction 1 (breast)
chr4_-_156285247 3.84 ENSMUST00000085425.6
ISG15 ubiquitin-like modifier
chr2_-_173060647 3.82 ENSMUST00000109116.3
ENSMUST00000029018.14
Z-DNA binding protein 1
chr4_+_34893772 3.80 ENSMUST00000029975.10
ENSMUST00000135871.8
ENSMUST00000108130.2
glycoprotein hormones, alpha subunit
chr14_+_40826970 3.79 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr11_+_58090382 3.79 ENSMUST00000035266.11
ENSMUST00000094169.11
ENSMUST00000168280.2
ENSMUST00000058704.9
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr1_+_85577709 3.77 ENSMUST00000155094.8
ENSMUST00000054279.15
ENSMUST00000147552.8
ENSMUST00000153574.8
ENSMUST00000150967.8
nuclear antigen Sp100
chr5_-_120915693 3.77 ENSMUST00000044833.9
2'-5' oligoadenylate synthetase 3
chr14_+_40827317 3.48 ENSMUST00000047286.7
methionine adenosyltransferase I, alpha
chr1_-_173594475 3.26 ENSMUST00000111214.4
interferon activated gene 204
chr12_+_26519203 3.11 ENSMUST00000020969.5
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_+_170846482 3.06 ENSMUST00000078825.5
Fc receptor, IgG, low affinity IV
chr16_+_23428650 3.00 ENSMUST00000038423.6
ENSMUST00000211349.2
receptor transporter protein 4
chr8_-_112064783 2.99 ENSMUST00000056157.14
ENSMUST00000120432.3
mixed lineage kinase domain-like
chrX_-_9335525 2.98 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr7_+_142014546 2.90 ENSMUST00000105968.8
ENSMUST00000018963.11
ENSMUST00000105967.8
lymphocyte specific 1
chr5_-_121045568 2.88 ENSMUST00000080322.8
2'-5' oligoadenylate synthetase 1A
chr16_-_35759461 2.86 ENSMUST00000081933.14
ENSMUST00000114885.3
deltex 3-like, E3 ubiquitin ligase
chr19_+_34585322 2.85 ENSMUST00000076249.6
interferon-induced protein with tetratricopeptide repeats 3B
chr18_+_60345152 2.75 ENSMUST00000031549.6
predicted gene 4951
chr1_-_85526517 2.71 ENSMUST00000093508.7
Sp110 nuclear body protein
chr11_-_118292678 2.54 ENSMUST00000106290.4
lectin, galactoside-binding, soluble, 3 binding protein
chr12_+_37291728 2.54 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr15_+_79776597 2.54 ENSMUST00000175714.8
ENSMUST00000109620.10
ENSMUST00000165537.8
ENSMUST00000175752.8
ENSMUST00000176325.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr17_+_43700327 2.51 ENSMUST00000113599.2
ENSMUST00000224278.2
ENSMUST00000225466.2
adhesion G protein-coupled receptor F5
chr13_+_74787952 2.50 ENSMUST00000221822.2
ENSMUST00000221526.2
endoplasmic reticulum aminopeptidase 1
chr5_-_92496730 2.49 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr1_-_173740467 2.35 ENSMUST00000009340.10
interferon activated gene 211
chr4_-_46536088 2.35 ENSMUST00000102924.3
ENSMUST00000046897.13
tripartite motif-containing 14
chr6_+_145067457 2.34 ENSMUST00000032396.13
lymphoid-restricted membrane protein
chr4_-_132125510 2.33 ENSMUST00000136711.2
ENSMUST00000084249.11
phosphatase and actin regulator 4
chr1_+_85577766 2.30 ENSMUST00000066427.11
nuclear antigen Sp100
chr11_+_119283887 2.29 ENSMUST00000093902.12
ENSMUST00000131035.10
ring finger protein 213
chr7_-_104114384 2.21 ENSMUST00000076922.6
tripartite motif-containing 30A
chr1_+_52158599 2.18 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
signal transducer and activator of transcription 1
chr17_+_34406523 2.16 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_20011251 2.12 ENSMUST00000108328.8
ceruloplasmin
chr11_-_48762170 2.11 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr3_+_20011405 2.11 ENSMUST00000108325.9
ceruloplasmin
chr7_-_140846328 2.01 ENSMUST00000106023.8
ENSMUST00000097952.9
ENSMUST00000026571.11
interferon regulatory factor 7
chr1_-_173569301 2.00 ENSMUST00000042610.15
ENSMUST00000127730.2
interferon activated gene 207
chr11_+_46701619 2.00 ENSMUST00000068877.7
T cell immunoglobulin and mucin domain containing 4
chr11_-_70350783 2.00 ENSMUST00000019064.9
chemokine (C-X-C motif) ligand 16
chr4_-_40239700 2.00 ENSMUST00000142055.2
DEAD/H box helicase 58
chr5_+_115034997 1.99 ENSMUST00000031542.13
ENSMUST00000146072.8
ENSMUST00000150361.2
2'-5' oligoadenylate synthetase-like 2
chr1_-_173770010 1.95 ENSMUST00000042228.15
ENSMUST00000081216.12
ENSMUST00000129829.8
ENSMUST00000123708.8
interferon activated gene 203
chr11_-_118292758 1.94 ENSMUST00000043722.10
lectin, galactoside-binding, soluble, 3 binding protein
chr19_+_12438125 1.93 ENSMUST00000081035.9
macrophage expressed gene 1
chr3_+_81839908 1.92 ENSMUST00000029649.3
cathepsin O
chr16_+_35758836 1.88 ENSMUST00000114878.8
poly (ADP-ribose) polymerase family, member 9
chr17_+_34406762 1.86 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_+_29344846 1.82 ENSMUST00000016640.8
CD274 antigen
chr1_+_52158693 1.81 ENSMUST00000189347.7
signal transducer and activator of transcription 1
chr18_-_33596890 1.80 ENSMUST00000237066.2
neuronal regeneration related protein
chr10_-_94780695 1.79 ENSMUST00000099337.5
plexin C1
chr2_-_166904625 1.79 ENSMUST00000128676.2
zinc finger, NFX1-type containing 1
chr1_-_173707677 1.77 ENSMUST00000190651.4
ENSMUST00000188804.7
myeloid nuclear differentiation antigen like
chr10_-_43880353 1.77 ENSMUST00000020017.14
crystallin beta-gamma domain containing 1
chr12_-_79027531 1.75 ENSMUST00000174072.8
transmembrane protein 229B
chr13_+_37529184 1.74 ENSMUST00000021860.7
lymphocyte antigen 86
chr4_+_135455427 1.73 ENSMUST00000102546.4
interleukin 22 receptor, alpha 1
chr6_+_128339882 1.73 ENSMUST00000073316.13
forkhead box M1
chr17_-_35392254 1.71 ENSMUST00000025257.12
allograft inflammatory factor 1
chr3_+_20011201 1.71 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr12_+_108601963 1.71 ENSMUST00000223109.2
Ena-vasodilator stimulated phosphoprotein
chr19_-_40502117 1.69 ENSMUST00000225148.2
ENSMUST00000224667.2
ENSMUST00000225153.2
ENSMUST00000238831.2
ENSMUST00000226047.2
ENSMUST00000224247.2
sorbin and SH3 domain containing 1
chr3_+_137377285 1.69 ENSMUST00000166899.3
predicted gene, 21962
chr3_-_14843512 1.68 ENSMUST00000094365.11
carbonic anhydrase 1
chr7_-_25488060 1.65 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr2_+_155224105 1.63 ENSMUST00000134218.2
transformation related protein 53 inducible nuclear protein 2
chr4_+_94627755 1.61 ENSMUST00000071168.6
TEK receptor tyrosine kinase
chr18_+_61178211 1.60 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr10_+_51367052 1.60 ENSMUST00000217705.2
ENSMUST00000078778.5
ENSMUST00000220182.2
ENSMUST00000220226.2
leukocyte immunoglobulin-like receptor, subfamily B, member 4A
chr17_+_29879684 1.57 ENSMUST00000235014.2
ENSMUST00000130423.4
cap methyltransferase 1
chr1_-_173859321 1.54 ENSMUST00000059226.7
interferon activated gene 205
chr12_-_79054050 1.54 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr2_-_180883813 1.53 ENSMUST00000094203.11
ENSMUST00000108831.8
helicase with zinc finger 2, transcriptional coactivator
chr19_-_43741363 1.51 ENSMUST00000045562.6
cytochrome c oxidase assembly protein 15
chr19_+_10819896 1.51 ENSMUST00000025646.3
solute carrier family 15, member 3
chr7_-_102214636 1.48 ENSMUST00000106913.3
ENSMUST00000033264.12
tripartite motif-containing 21
chr14_+_14475188 1.48 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr3_-_104725853 1.47 ENSMUST00000106775.8
ENSMUST00000166979.8
Mov10 RISC complex RNA helicase
chr16_+_35759346 1.47 ENSMUST00000023622.13
poly (ADP-ribose) polymerase family, member 9
chr3_+_89638044 1.45 ENSMUST00000029563.14
ENSMUST00000121094.8
ENSMUST00000118341.6
ENSMUST00000107405.6
adenosine deaminase, RNA-specific
chr14_+_11307729 1.42 ENSMUST00000160956.2
ENSMUST00000160340.8
ENSMUST00000162278.8
fragile histidine triad gene
chr1_-_173318607 1.42 ENSMUST00000160565.4
interferon activated gene 206
chr7_+_130179063 1.40 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
transforming, acidic coiled-coil containing protein 2
chr7_-_104157006 1.40 ENSMUST00000033211.14
ENSMUST00000071069.13
tripartite motif-containing 30D
chr1_+_171216480 1.40 ENSMUST00000056449.9
Rho GTPase activating protein 30
chr10_+_128106414 1.40 ENSMUST00000085708.3
ENSMUST00000105238.10
signal transducer and activator of transcription 2
chr3_-_104725581 1.39 ENSMUST00000168015.8
Mov10 RISC complex RNA helicase
chr1_+_52158721 1.39 ENSMUST00000186057.7
signal transducer and activator of transcription 1
chr15_+_81629258 1.39 ENSMUST00000109554.3
ENSMUST00000230946.2
zinc finger CCCH type containing 7B
chr11_+_72192455 1.37 ENSMUST00000151440.8
ENSMUST00000146233.8
ENSMUST00000140842.9
XIAP associated factor 1
chr5_-_120887864 1.37 ENSMUST00000053909.13
ENSMUST00000081491.13
2'-5' oligoadenylate synthetase 2
chr7_-_101667346 1.35 ENSMUST00000209844.2
ENSMUST00000211502.2
ENSMUST00000094134.5
interleukin 18 binding protein
chr7_+_100742070 1.35 ENSMUST00000208439.2
FCH and double SH3 domains 2
chr3_-_136031799 1.33 ENSMUST00000196159.5
ENSMUST00000041577.13
B cell scaffold protein with ankyrin repeats 1
chr12_-_80307110 1.32 ENSMUST00000021554.16
actinin, alpha 1
chr16_-_35691914 1.31 ENSMUST00000042665.9
poly (ADP-ribose) polymerase family, member 14
chr3_-_104725535 1.30 ENSMUST00000002297.12
Mov10 RISC complex RNA helicase
chr18_-_33596792 1.29 ENSMUST00000051087.16
neuronal regeneration related protein
chr11_+_88890202 1.27 ENSMUST00000100627.9
ENSMUST00000107896.10
ENSMUST00000000284.7
tripartite motif-containing 25
chr4_+_94627513 1.26 ENSMUST00000073939.13
ENSMUST00000102798.8
TEK receptor tyrosine kinase
chr12_+_37292029 1.26 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr5_-_121025645 1.24 ENSMUST00000086368.12
2'-5' oligoadenylate synthetase 1G
chr7_+_78563184 1.24 ENSMUST00000121645.8
interferon-stimulated protein
chr18_-_33597060 1.23 ENSMUST00000168890.2
neuronal regeneration related protein
chr13_-_56326695 1.22 ENSMUST00000225063.2
TRAF-interacting protein with forkhead-associated domain, family member B
chr10_+_122514669 1.21 ENSMUST00000161487.8
ENSMUST00000067918.12
protein phosphatase 1H (PP2C domain containing)
chr9_-_58156982 1.20 ENSMUST00000135310.8
ENSMUST00000085673.11
ENSMUST00000114136.9
ENSMUST00000153820.8
ENSMUST00000124982.2
promyelocytic leukemia
chr19_+_6214416 1.19 ENSMUST00000045042.8
ENSMUST00000237511.2
basic leucine zipper transcription factor, ATF-like 2
chr16_+_26400454 1.19 ENSMUST00000096129.9
ENSMUST00000166294.9
ENSMUST00000174202.8
ENSMUST00000023156.13
interleukin 1 receptor accessory protein
chr3_+_142265787 1.19 ENSMUST00000199325.5
ENSMUST00000106222.9
guanylate binding protein 3
chr12_+_108602008 1.19 ENSMUST00000172409.2
Ena-vasodilator stimulated phosphoprotein
chr6_+_57557978 1.16 ENSMUST00000031817.10
hect domain and RLD 6
chr4_-_58911902 1.14 ENSMUST00000134848.2
ENSMUST00000107557.9
ENSMUST00000149301.8
Ecm29 proteasome adaptor and scaffold
chr4_+_138700195 1.11 ENSMUST00000123636.8
ENSMUST00000043042.10
ENSMUST00000050949.9
transmembrane and coiled-coil domains 4
chr2_-_180883746 1.10 ENSMUST00000121484.2
helicase with zinc finger 2, transcriptional coactivator
chr11_-_48941949 1.05 ENSMUST00000132768.2
ENSMUST00000101295.9
ENSMUST00000093152.2
RIKEN cDNA 9930111J21 gene 2
chr14_+_55842002 1.04 ENSMUST00000138037.2
interferon regulatory factor 9
chr11_+_72580823 1.04 ENSMUST00000155998.2
ankyrin repeat and FYVE domain containing 1
chr19_-_4384029 1.02 ENSMUST00000176653.2
lysine (K)-specific demethylase 2A
chr9_-_58156935 1.02 ENSMUST00000124063.2
ENSMUST00000126690.8
promyelocytic leukemia
chr17_-_35081129 1.02 ENSMUST00000154526.8
complement factor B
chr7_+_78563964 1.02 ENSMUST00000120331.4
interferon-stimulated protein
chr15_-_66684442 0.99 ENSMUST00000100572.10
src-like adaptor
chr2_-_35994072 0.99 ENSMUST00000112961.10
ENSMUST00000112966.10
LIM homeobox protein 6
chr11_+_106642052 0.99 ENSMUST00000147326.9
ENSMUST00000182896.8
ENSMUST00000182908.8
ENSMUST00000086353.11
mast cell immunoglobulin like receptor 1
chr18_-_78185334 0.98 ENSMUST00000160639.2
solute carrier family 14 (urea transporter), member 1
chr4_-_40239778 0.98 ENSMUST00000037907.13
DEAD/H box helicase 58
chr18_-_33596468 0.97 ENSMUST00000171533.9
neuronal regeneration related protein
chr8_-_112064393 0.97 ENSMUST00000145862.3
mixed lineage kinase domain-like
chr12_+_37291632 0.97 ENSMUST00000049874.14
alkylglycerol monooxygenase
chr4_-_136626073 0.97 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr14_+_48683581 0.96 ENSMUST00000227440.2
ENSMUST00000124720.8
ENSMUST00000226422.2
ENSMUST00000226400.2
transmembrane protein 260
chr2_-_132095146 0.95 ENSMUST00000028817.7
proliferating cell nuclear antigen
chr7_+_43057611 0.92 ENSMUST00000005592.7
sialic acid binding Ig-like lectin G
chr5_-_134258435 0.90 ENSMUST00000016094.13
ENSMUST00000111275.8
ENSMUST00000144086.2
neutrophil cytosolic factor 1
chr16_-_43959361 0.89 ENSMUST00000124102.8
ATPase, H+ transporting, lysosomal V1 subunit A
chr3_-_32670628 0.86 ENSMUST00000193050.2
ENSMUST00000108234.8
ENSMUST00000155737.8
guanine nucleotide binding protein (G protein), beta 4
chr13_-_56326511 0.84 ENSMUST00000169652.3
TRAF-interacting protein with forkhead-associated domain, family member B
chr14_+_55815999 0.83 ENSMUST00000172738.2
ENSMUST00000089619.13
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr11_+_43365103 0.82 ENSMUST00000173002.8
ENSMUST00000057679.10
C1q and tumor necrosis factor related protein 2
chr14_+_55815879 0.82 ENSMUST00000174563.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr14_+_55815580 0.80 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr9_-_58065800 0.80 ENSMUST00000168864.4
immunoglobulin superfamily containing leucine-rich repeat
chr5_+_34494272 0.78 ENSMUST00000182047.2
ring finger protein 4
chr2_-_131953359 0.78 ENSMUST00000128899.2
solute carrier family 23 (nucleobase transporters), member 2
chr1_+_34511793 0.77 ENSMUST00000188972.3
protein tyrosine phosphatase, non-receptor type 18
chr17_+_34354556 0.77 ENSMUST00000236322.2
ENSMUST00000237402.2
histocompatibility 2, class II, locus DMa
chr7_+_78563513 0.76 ENSMUST00000038142.15
interferon-stimulated protein
chr11_-_48870105 0.76 ENSMUST00000141200.2
ENSMUST00000097494.9
ENSMUST00000093153.2
RIKEN cDNA 9930111J21 gene 1
chr9_-_110819639 0.76 ENSMUST00000198702.2
receptor transporter protein 3
chr18_+_65022035 0.75 ENSMUST00000224385.3
ENSMUST00000163516.9
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr3_+_94861386 0.75 ENSMUST00000107260.9
ENSMUST00000142311.8
ENSMUST00000137088.8
ENSMUST00000152869.8
ENSMUST00000107254.8
ENSMUST00000107253.8
regulatory factor X, 5 (influences HLA class II expression)
chr3_+_142266113 0.75 ENSMUST00000106221.8
guanylate binding protein 3
chr1_+_173501215 0.73 ENSMUST00000085876.12
interferon activated gene 208
chr3_-_59038031 0.73 ENSMUST00000091112.6
ENSMUST00000065220.13
purinergic receptor P2Y, G-protein coupled, 14
chr17_+_37148015 0.73 ENSMUST00000179968.8
ENSMUST00000130367.8
ENSMUST00000053434.15
ENSMUST00000130801.8
ENSMUST00000144182.8
ENSMUST00000123715.8
tripartite motif-containing 26
chr11_+_115725140 0.72 ENSMUST00000173289.8
ENSMUST00000137900.2
LLGL2 scribble cell polarity complex component
chr5_-_90487583 0.72 ENSMUST00000197021.2
ankyrin repeat domain 17
chr9_+_107852733 0.71 ENSMUST00000035216.11
ubiquitin-like modifier activating enzyme 7
chr7_+_103893658 0.71 ENSMUST00000106849.9
ENSMUST00000060315.12
tripartite motif-containing 34A
chr17_-_35081456 0.70 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr16_-_43959993 0.70 ENSMUST00000137557.8
ATPase, H+ transporting, lysosomal V1 subunit A
chr13_+_120761861 0.70 ENSMUST00000225029.2
cDNA sequence BC147527
chr2_-_152239966 0.70 ENSMUST00000063332.9
ENSMUST00000182625.2
SRY (sex determining region Y)-box 12
chr11_-_82882613 0.70 ENSMUST00000092840.11
ENSMUST00000038211.13
schlafen 9
chr13_-_103901010 0.68 ENSMUST00000210489.2
splicing regulatory glutamine/lysine-rich protein 1
chr14_-_63781381 0.67 ENSMUST00000058679.7
myotubularin related protein 9
chr7_+_75351713 0.67 ENSMUST00000207239.2
A kinase (PRKA) anchor protein 13
chr3_-_136031723 0.66 ENSMUST00000198206.2
B cell scaffold protein with ankyrin repeats 1
chr11_-_121120052 0.66 ENSMUST00000169393.8
ENSMUST00000106115.8
ENSMUST00000038709.14
ENSMUST00000147490.6
cytochrome b 245 chaperone 1
chr3_+_142265904 0.65 ENSMUST00000128609.8
ENSMUST00000029935.14
guanylate binding protein 3
chr7_+_78564062 0.64 ENSMUST00000205981.2
interferon-stimulated protein
chr17_+_29879569 0.63 ENSMUST00000024816.13
ENSMUST00000235031.2
ENSMUST00000234911.2
cap methyltransferase 1
chr5_+_34493633 0.62 ENSMUST00000182709.8
ENSMUST00000030992.13
ring finger protein 4
chr6_-_39095144 0.61 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chrX_+_80114242 0.59 ENSMUST00000171953.8
ENSMUST00000026760.3
transmembrane protein 47
chr4_+_108691798 0.59 ENSMUST00000030296.9
thioredoxin domain containing 12 (endoplasmic reticulum)
chr2_-_120370333 0.59 ENSMUST00000171215.8
zinc finger protein 106
chr14_+_55815817 0.56 ENSMUST00000174259.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_-_105229653 0.55 ENSMUST00000006128.7
reticulocalbin 1
chr11_-_51748450 0.54 ENSMUST00000020655.14
ENSMUST00000109090.8
jade family PHD finger 2
chr17_-_34406193 0.52 ENSMUST00000173831.3
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr17_+_34138699 0.52 ENSMUST00000234320.2
TAP binding protein
chr1_-_184464810 0.52 ENSMUST00000048572.7
H2.0-like homeobox
chr4_-_42773987 0.50 ENSMUST00000095114.5
chemokine (C-C motif) ligand 21A (serine)

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0009087 methionine catabolic process(GO:0009087)
1.8 5.4 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
1.4 5.8 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
1.3 4.0 GO:0046967 cytosol to ER transport(GO:0046967)
1.3 5.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.3 3.8 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
1.0 4.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.0 3.1 GO:0006233 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.6 2.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.6 3.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 3.0 GO:0035546 detection of virus(GO:0009597) interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.6 11.8 GO:0031000 response to caffeine(GO:0031000)
0.6 29.9 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.6 2.3 GO:0061386 closure of optic fissure(GO:0061386)
0.6 2.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.6 1.7 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.6 4.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.6 9.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.5 1.6 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.5 2.0 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.5 1.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.5 3.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.4 1.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 2.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.4 2.1 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.4 4.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.4 2.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.4 3.0 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.4 4.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.4 0.7 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 3.5 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.3 2.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.3 2.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.3 0.9 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.3 3.8 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.3 0.8 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 0.8 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.2 1.0 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 3.0 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 2.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.4 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.2 2.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 1.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 2.5 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 0.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 1.4 GO:0018377 protein myristoylation(GO:0018377)
0.2 2.0 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.2 1.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 5.2 GO:0035634 response to stilbenoid(GO:0035634)
0.2 5.9 GO:0046688 copper ion transport(GO:0006825) response to copper ion(GO:0046688)
0.2 1.4 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.1 1.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.7 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 1.5 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 2.5 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 1.0 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 6.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:0009397 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 3.1 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.7 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 1.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 2.0 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 1.2 GO:0072602 interleukin-4 secretion(GO:0072602)
0.1 0.7 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.5 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.4 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 2.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 1.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 2.4 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 1.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 1.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.7 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.1 0.8 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.1 2.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 2.4 GO:0070266 necroptotic process(GO:0070266)
0.1 0.7 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.4 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.1 2.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.2 GO:0050822 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 1.8 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 1.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 4.2 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 1.7 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 3.0 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.2 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 12.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.5 4.2 GO:0042825 TAP complex(GO:0042825)
0.5 3.0 GO:0008537 proteasome activator complex(GO:0008537)
0.4 1.3 GO:0032127 dense core granule membrane(GO:0032127)
0.3 1.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 2.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 1.7 GO:0005899 insulin receptor complex(GO:0005899)
0.3 9.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 3.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 1.7 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.5 GO:0042629 mast cell granule(GO:0042629)
0.1 1.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.1 GO:0044754 autolysosome(GO:0044754)
0.1 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0097443 sorting endosome(GO:0097443)
0.1 10.8 GO:0016605 PML body(GO:0016605)
0.1 5.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 12.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 6.2 GO:0005811 lipid particle(GO:0005811)
0.1 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 12.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0070069 cytochrome complex(GO:0070069)
0.0 3.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 3.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.1 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 17.9 GO:0005730 nucleolus(GO:0005730)
0.0 3.7 GO:0030027 lamellipodium(GO:0030027)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 12.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
3.0 9.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
1.8 5.3 GO:0003692 left-handed Z-DNA binding(GO:0003692)
1.7 5.1 GO:0031726 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
1.6 4.8 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
1.3 4.0 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
1.0 3.1 GO:0004798 thymidylate kinase activity(GO:0004798)
0.8 9.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.7 3.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 3.1 GO:0019767 IgE receptor activity(GO:0019767)
0.6 1.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.5 5.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 5.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.5 1.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.5 3.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 2.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.4 2.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 3.8 GO:0051434 BH3 domain binding(GO:0051434)
0.4 2.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4 1.4 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.3 1.0 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.3 1.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.3 2.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 3.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 0.8 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 3.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 2.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 3.8 GO:0031386 protein tag(GO:0031386)
0.2 1.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 0.6 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.2 1.0 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 2.9 GO:0005522 profilin binding(GO:0005522)
0.2 1.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 1.7 GO:0004064 arylesterase activity(GO:0004064)
0.2 4.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.0 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 5.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 4.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 5.7 GO:0019003 GDP binding(GO:0019003)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 12.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 9.6 GO:0004386 helicase activity(GO:0004386)
0.0 1.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 6.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 13.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 13.4 GO:0001047 core promoter binding(GO:0001047)
0.0 5.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 2.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 1.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 6.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 7.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.2 PID MYC PATHWAY C-MYC pathway
0.1 1.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 13.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 3.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.7 PID INSULIN PATHWAY Insulin Pathway
0.0 1.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.0 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.8 REACTOME DEFENSINS Genes involved in Defensins
0.4 10.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.4 3.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 12.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 6.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 9.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 13.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 8.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 4.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 8.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 2.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 3.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 5.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 4.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 5.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.3 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases