GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Tbp Links Ensembl NCBI MGI UniProt	ENSMUSG00000014767.18	TATA box binding protein

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tbp	mm39_v1_chr17_+_15720150_15720222	0.53	9.3e-04	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_90603013 Show fit	42.90	ENSMUST00000069960.12 ENSMUST00000117167.2	S100a9 Links Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A9 (calgranulin B)
chr11_+_87684299 Show fit	33.63	ENSMUST00000020779.11	Mpo Links Ensembl NCBI MGI UniProt Show fit	myeloperoxidase
chr5_+_90920294 Show fit	29.10	ENSMUST00000031320.8	Pf4 Links Ensembl NCBI MGI UniProt Show fit	platelet factor 4
chr5_+_90920353 Show fit	27.87	ENSMUST00000202625.2	Pf4 Links Ensembl NCBI MGI UniProt Show fit	platelet factor 4
chr9_+_98372575 Show fit	27.82	ENSMUST00000035029.3	Rbp2 Links Ensembl NCBI MGI UniProt Show fit	retinol binding protein 2, cellular
chr4_+_120523758 Show fit	25.96	ENSMUST00000094814.6	Cited4 Links Ensembl NCBI MGI UniProt Show fit	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr7_-_103463120 Show fit	25.60	ENSMUST00000098192.4	Hbb-bt Links Ensembl NCBI MGI UniProt Show fit	hemoglobin, beta adult t chain
chr6_-_41291634 Show fit	23.71	ENSMUST00000064324.12	Try5 Links Ensembl NCBI MGI UniProt Show fit	trypsin 5
chr17_-_31348576 Show fit	23.42	ENSMUST00000024827.5	Tff3 Links Ensembl NCBI MGI UniProt Show fit	trefoil factor 3, intestinal
chr7_-_103477126 Show fit	22.12	ENSMUST00000023934.8	Hbb-bs Links Ensembl NCBI MGI UniProt Show fit	hemoglobin, beta adult s chain
chr7_-_45175570 Show fit	21.46	ENSMUST00000167273.2 ENSMUST00000042105.11	Ppp1r15a Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 15A
chr8_+_94905710 Show fit	21.43	ENSMUST00000034215.8 ENSMUST00000212291.2 ENSMUST00000211807.2	Mt1 Links Ensembl NCBI MGI UniProt Show fit	metallothionein 1
chr6_-_41354538 Show fit	21.21	ENSMUST00000096003.7	Prss3 Links Ensembl NCBI MGI UniProt Show fit	protease, serine 3
chr1_+_134110142 Show fit	21.20	ENSMUST00000082060.10 ENSMUST00000153856.8 ENSMUST00000133701.8 ENSMUST00000132873.8	Chil1 Links Ensembl NCBI MGI UniProt Show fit	chitinase-like 1
chr14_-_56339915 Show fit	20.57	ENSMUST00000015583.2	Ctsg Links Ensembl NCBI MGI UniProt Show fit	cathepsin G
chr7_-_4815111 Show fit	19.84	ENSMUST00000205885.2	Ube2s Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-conjugating enzyme E2S
chr3_-_20329823 Show fit	17.75	ENSMUST00000011607.6	Cpb1 Links Ensembl NCBI MGI UniProt Show fit	carboxypeptidase B1 (tissue)
chr11_-_55075855 Show fit	17.60	ENSMUST00000039305.6	Slc36a2 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 36 (proton/amino acid symporter), member 2
chr7_-_4815542 Show fit	17.45	ENSMUST00000079496.9	Ube2s Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-conjugating enzyme E2S
chr8_+_85696216 Show fit	16.95	ENSMUST00000109734.8 ENSMUST00000005292.15	Prdx2 Links Ensembl NCBI MGI UniProt Show fit	peroxiredoxin 2
chr1_+_134109888 Show fit	16.20	ENSMUST00000156873.8	Chil1 Links Ensembl NCBI MGI UniProt Show fit	chitinase-like 1
chr8_+_85696453 Show fit	16.02	ENSMUST00000125893.8	Prdx2 Links Ensembl NCBI MGI UniProt Show fit	peroxiredoxin 2
chr11_-_99328969 Show fit	15.65	ENSMUST00000017743.3	Krt20 Links Ensembl NCBI MGI UniProt Show fit	keratin 20
chr6_+_41331039 Show fit	15.13	ENSMUST00000072103.7	Try10 Links Ensembl NCBI MGI UniProt Show fit	trypsin 10
chr7_-_143056252 Show fit	15.03	ENSMUST00000010904.5	Phlda2 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology like domain, family A, member 2
chr8_+_85696396 Show fit	14.90	ENSMUST00000109733.8	Prdx2 Links Ensembl NCBI MGI UniProt Show fit	peroxiredoxin 2
chr9_+_7558449 Show fit	14.36	ENSMUST00000018765.4	Mmp8 Links Ensembl NCBI MGI UniProt Show fit	matrix metallopeptidase 8
chr2_-_164197987 Show fit	13.75	ENSMUST00000165980.2	Slpi Links Ensembl NCBI MGI UniProt Show fit	secretory leukocyte peptidase inhibitor
chr13_-_22017677 Show fit	13.73	ENSMUST00000081342.7	H2ac24 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 24
chr6_-_41012435 Show fit	13.65	ENSMUST00000031931.6	2210010C04Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2210010C04 gene
chr11_-_98915005 Show fit	13.64	ENSMUST00000068031.8	Top2a Links Ensembl NCBI MGI UniProt Show fit	topoisomerase (DNA) II alpha
chr6_-_87958611 Show fit	13.60	ENSMUST00000056403.7	H1f10 Links Ensembl NCBI MGI UniProt Show fit	H1.10 linker histone
chr6_-_57802131 Show fit	13.57	ENSMUST00000204878.3 ENSMUST00000145608.7 ENSMUST00000203212.3 ENSMUST00000114297.5	Vopp1 Links Ensembl NCBI MGI UniProt Show fit	vesicular, overexpressed in cancer, prosurvival protein 1
chr2_-_164198427 Show fit	13.50	ENSMUST00000109367.10	Slpi Links Ensembl NCBI MGI UniProt Show fit	secretory leukocyte peptidase inhibitor
chr6_-_72935468 Show fit	13.50	ENSMUST00000114050.8	Tmsb10 Links Ensembl NCBI MGI UniProt Show fit	thymosin, beta 10
chr6_+_41435846 Show fit	13.00	ENSMUST00000031910.8	Prss1 Links Ensembl NCBI MGI UniProt Show fit	protease, serine 1 (trypsin 1)
chr11_-_69838971 Show fit	12.65	ENSMUST00000179298.3 ENSMUST00000018710.13 ENSMUST00000135437.3 ENSMUST00000141837.9 ENSMUST00000142500.8	Slc2a4 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 4
chr6_+_41369290 Show fit	12.56	ENSMUST00000049079.9	Gm5771 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 5771
chr11_-_102787950 Show fit	12.33	ENSMUST00000067444.10	Gfap Links Ensembl NCBI MGI UniProt Show fit	glial fibrillary acidic protein
chr7_-_44181477 Show fit	12.18	ENSMUST00000098483.9 ENSMUST00000035323.6	Spib Links Ensembl NCBI MGI UniProt Show fit	Spi-B transcription factor (Spi-1/PU.1 related)
chr8_+_85696695 Show fit	11.78	ENSMUST00000164807.2	Prdx2 Links Ensembl NCBI MGI UniProt Show fit	peroxiredoxin 2
chr6_-_72935382 Show fit	11.63	ENSMUST00000144337.2	Tmsb10 Links Ensembl NCBI MGI UniProt Show fit	thymosin, beta 10
chr11_-_115405200 Show fit	11.58	ENSMUST00000021083.7	Jpt1 Links Ensembl NCBI MGI UniProt Show fit	Jupiter microtubule associated homolog 1
chr2_+_119449192 Show fit	11.55	ENSMUST00000028771.8	Nusap1 Links Ensembl NCBI MGI UniProt Show fit	nucleolar and spindle associated protein 1
chr18_-_78166595 Show fit	11.46	ENSMUST00000091813.12	Slc14a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 14 (urea transporter), member 1
chr7_-_103502404 Show fit	11.40	ENSMUST00000033229.5	Hbb-y Links Ensembl NCBI MGI UniProt Show fit	hemoglobin Y, beta-like embryonic chain
chr4_-_41098174 Show fit	11.35	ENSMUST00000055327.8	Aqp3 Links Ensembl NCBI MGI UniProt Show fit	aquaporin 3
chr17_+_24939072 Show fit	11.15	ENSMUST00000054289.13	Rps2 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S2
chr17_+_24939225 Show fit	10.27	ENSMUST00000146867.2	Rps2 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S2
chr11_+_76889415 Show fit	10.04	ENSMUST00000108402.9 ENSMUST00000021195.11	Slc6a4 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr17_+_24939037 Show fit	10.01	ENSMUST00000170715.8	Rps2 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S2
chr13_-_22225527 Show fit	9.90	ENSMUST00000102977.4	H4c9 Links Ensembl NCBI MGI UniProt Show fit	H4 clustered histone 9
chr2_+_13579092 Show fit	9.88	ENSMUST00000193675.2	Vim Links Ensembl NCBI MGI UniProt Show fit	vimentin
chr18_-_78166539 Show fit	9.83	ENSMUST00000160292.8	Slc14a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 14 (urea transporter), member 1
chr2_+_13578738 Show fit	9.50	ENSMUST00000141365.3 ENSMUST00000028062.8	Vim Links Ensembl NCBI MGI UniProt Show fit	vimentin
chr7_-_126651847 Show fit	9.50	ENSMUST00000205424.2	Zg16 Links Ensembl NCBI MGI UniProt Show fit	zymogen granule protein 16
chr17_-_34043502 Show fit	9.50	ENSMUST00000087342.13 ENSMUST00000173844.8	Rps28 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S28
chr6_-_72935171 Show fit	9.21	ENSMUST00000114049.2	Tmsb10 Links Ensembl NCBI MGI UniProt Show fit	thymosin, beta 10
chr18_+_34758062 Show fit	9.15	ENSMUST00000166044.3	Kif20a Links Ensembl NCBI MGI UniProt Show fit	kinesin family member 20A
chr17_-_34043320 Show fit	8.98	ENSMUST00000173879.8 ENSMUST00000166693.3 ENSMUST00000173019.8	Rps28 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S28
chr17_+_23945310 Show fit	8.84	ENSMUST00000024701.9	Pkmyt1 Links Ensembl NCBI MGI UniProt Show fit	protein kinase, membrane associated tyrosine/threonine 1
chr1_-_134006847 Show fit	8.81	ENSMUST00000020692.7	Btg2 Links Ensembl NCBI MGI UniProt Show fit	BTG anti-proliferation factor 2
chr2_-_119448935 Show fit	8.72	ENSMUST00000123818.2	Oip5 Links Ensembl NCBI MGI UniProt Show fit	Opa interacting protein 5
chr8_-_106660470 Show fit	8.59	ENSMUST00000034368.8	Ctrl Links Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like
chr4_-_132080916 Show fit	8.32	ENSMUST00000155129.2 ENSMUST00000151374.2	Rcc1 Links Ensembl NCBI MGI UniProt Show fit Snhg3 Links Ensembl NCBI MGI UniProt Show fit	regulator of chromosome condensation 1 small nucleolar RNA host gene 3
chr15_-_79967543 Show fit	8.32	ENSMUST00000081650.15	Rpl3 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L3
chr18_+_34757687 Show fit	7.91	ENSMUST00000237407.2	Kif20a Links Ensembl NCBI MGI UniProt Show fit	kinesin family member 20A
chr2_-_113883285 Show fit	7.91	ENSMUST00000090269.7	Actc1 Links Ensembl NCBI MGI UniProt Show fit	actin, alpha, cardiac muscle 1
chr10_-_35587888 Show fit	7.87	ENSMUST00000080898.4	Amd2 Links Ensembl NCBI MGI UniProt Show fit	S-adenosylmethionine decarboxylase 2
chr10_-_128462616 Show fit	7.80	ENSMUST00000026420.7	Rps26 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S26
chr11_+_94827050 Show fit	7.66	ENSMUST00000001547.8	Col1a1 Links Ensembl NCBI MGI UniProt Show fit	collagen, type I, alpha 1
chr7_-_15993110 Show fit	7.57	ENSMUST00000168818.2	C5ar1 Links Ensembl NCBI MGI UniProt Show fit	complement component 5a receptor 1
chr9_-_61821820 Show fit	7.55	ENSMUST00000008036.9	Rplp1 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein, large, P1
chr4_+_118965908 Show fit	7.51	ENSMUST00000030398.10	Slc2a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 1
chr18_+_34757666 Show fit	7.40	ENSMUST00000167161.9	Kif20a Links Ensembl NCBI MGI UniProt Show fit	kinesin family member 20A
chr15_-_66841465 Show fit	7.25	ENSMUST00000170903.8 ENSMUST00000166420.8 ENSMUST00000005256.14 ENSMUST00000164070.2	Ndrg1 Links Ensembl NCBI MGI UniProt Show fit	N-myc downstream regulated gene 1
chr10_-_80512117 Show fit	7.21	ENSMUST00000200082.5	Mknk2 Links Ensembl NCBI MGI UniProt Show fit	MAP kinase-interacting serine/threonine kinase 2
chr11_-_101998648 Show fit	7.14	ENSMUST00000177304.8 ENSMUST00000017455.15	Pyy Links Ensembl NCBI MGI UniProt Show fit	peptide YY
chr11_+_67167950 Show fit	6.97	ENSMUST00000019625.12	Myh8 Links Ensembl NCBI MGI UniProt Show fit	myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr17_-_34174631 Show fit	6.87	ENSMUST00000174609.9 ENSMUST00000008812.9	Rps18 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S18
chr2_-_25114660 Show fit	6.80	ENSMUST00000043584.5	Tubb4b Links Ensembl NCBI MGI UniProt Show fit	tubulin, beta 4B class IVB
chr4_+_118965992 Show fit	6.75	ENSMUST00000134105.8 ENSMUST00000144329.8 ENSMUST00000208090.2	Slc2a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 1
chr1_-_172722589 Show fit	6.73	ENSMUST00000027824.7	Apcs Links Ensembl NCBI MGI UniProt Show fit	serum amyloid P-component
chr4_-_3835595 Show fit	6.65	ENSMUST00000138502.2	Rps20 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S20
chr17_-_80514725 Show fit	6.35	ENSMUST00000234696.2 ENSMUST00000235069.2 ENSMUST00000063417.11	Srsf7 Links Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 7
chr6_-_40976413 Show fit	6.32	ENSMUST00000166306.3	Gm2663 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 2663
chr11_-_33113071 Show fit	6.31	ENSMUST00000093201.13 ENSMUST00000101375.5 ENSMUST00000109354.10 ENSMUST00000075641.10	Npm1 Links Ensembl NCBI MGI UniProt Show fit	nucleophosmin 1
chr2_+_152578164 Show fit	6.29	ENSMUST00000038368.9 ENSMUST00000109824.2	Id1 Links Ensembl NCBI MGI UniProt Show fit	inhibitor of DNA binding 1, HLH protein
chr13_+_21900554 Show fit	6.10	ENSMUST00000070124.5	H2ac13 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 13
chr5_+_139239247 Show fit	6.09	ENSMUST00000138508.8 ENSMUST00000110878.2	Get4 Links Ensembl NCBI MGI UniProt Show fit	golgi to ER traffic protein 4
chr6_+_4747298 Show fit	5.97	ENSMUST00000166678.2 ENSMUST00000176204.8	Peg10 Links Ensembl NCBI MGI UniProt Show fit	paternally expressed 10
chr6_+_78402956 Show fit	5.83	ENSMUST00000079926.6	Reg1 Links Ensembl NCBI MGI UniProt Show fit	regenerating islet-derived 1
chr4_+_126915104 Show fit	5.75	ENSMUST00000030623.8	Sfpq Links Ensembl NCBI MGI UniProt Show fit	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr4_+_34893772 Show fit	5.64	ENSMUST00000029975.10 ENSMUST00000135871.8 ENSMUST00000108130.2	Cga Links Ensembl NCBI MGI UniProt Show fit	glycoprotein hormones, alpha subunit
chr3_+_145855929 Show fit	5.60	ENSMUST00000098524.5	Mcoln2 Links Ensembl NCBI MGI UniProt Show fit	mucolipin 2
chr9_+_108385247 Show fit	5.59	ENSMUST00000207810.2 ENSMUST00000207862.2 ENSMUST00000208581.2 ENSMUST00000134939.9 ENSMUST00000207713.2	Qars Links Ensembl NCBI MGI UniProt Show fit	glutaminyl-tRNA synthetase
chr3_-_20296337 Show fit	5.52	ENSMUST00000001921.3	Cpa3 Links Ensembl NCBI MGI UniProt Show fit	carboxypeptidase A3, mast cell
chr10_-_88440869 Show fit	5.47	ENSMUST00000119185.8 ENSMUST00000238199.2	Mybpc1 Links Ensembl NCBI MGI UniProt Show fit	myosin binding protein C, slow-type
chr11_-_102787972 Show fit	5.43	ENSMUST00000077902.5	Gfap Links Ensembl NCBI MGI UniProt Show fit	glial fibrillary acidic protein
chr2_+_122479770 Show fit	5.28	ENSMUST00000047498.15 ENSMUST00000110512.4	AA467197 Links Ensembl NCBI MGI UniProt Show fit	expressed sequence AA467197
chr8_-_71292295 Show fit	5.24	ENSMUST00000212405.2 ENSMUST00000002989.11	Arrdc2 Links Ensembl NCBI MGI UniProt Show fit	arrestin domain containing 2
chr2_+_90927053 Show fit	5.14	ENSMUST00000132741.3	Spi1 Links Ensembl NCBI MGI UniProt Show fit	spleen focus forming virus (SFFV) proviral integration oncogene
chr7_-_30643444 Show fit	5.12	ENSMUST00000062620.9	Hamp Links Ensembl NCBI MGI UniProt Show fit	hepcidin antimicrobial peptide
chr10_-_88440996 Show fit	5.09	ENSMUST00000121629.8	Mybpc1 Links Ensembl NCBI MGI UniProt Show fit	myosin binding protein C, slow-type
chr6_+_40941688 Show fit	5.09	ENSMUST00000076638.7	1810009J06Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1810009J06 gene
chr2_+_36120438 Show fit	5.01	ENSMUST00000062069.6	Ptgs1 Links Ensembl NCBI MGI UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr1_-_66974492 Show fit	5.00	ENSMUST00000120415.8 ENSMUST00000119429.8	Myl1 Links Ensembl NCBI MGI UniProt Show fit	myosin, light polypeptide 1
chr3_+_142470806 Show fit	4.92	ENSMUST00000029938.10	Gtf2b Links Ensembl NCBI MGI UniProt Show fit	general transcription factor IIB
chr13_+_21901791 Show fit	4.84	ENSMUST00000188775.2	H3c10 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 10
chr5_+_142946098 Show fit	4.83	ENSMUST00000031565.15 ENSMUST00000198017.5	Fscn1 Links Ensembl NCBI MGI UniProt Show fit	fascin actin-bundling protein 1
chr6_-_4747157 Show fit	4.82	ENSMUST00000126151.8 ENSMUST00000115577.9 ENSMUST00000101677.9 ENSMUST00000115579.8 ENSMUST00000004750.15	Sgce Links Ensembl NCBI MGI UniProt Show fit	sarcoglycan, epsilon
chr19_+_39049442 Show fit	4.82	ENSMUST00000087236.5	Cyp2c65 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 65
chr7_+_130633776 Show fit	4.79	ENSMUST00000084509.7 ENSMUST00000213064.3 ENSMUST00000208311.4	Dmbt1 Links Ensembl NCBI MGI UniProt Show fit	deleted in malignant brain tumors 1
chr4_-_116484675 Show fit	4.78	ENSMUST00000081182.5 ENSMUST00000030457.12	Nasp Links Ensembl NCBI MGI UniProt Show fit	nuclear autoantigenic sperm protein (histone-binding)
chr17_+_29251602 Show fit	4.76	ENSMUST00000130216.3	Srsf3 Links Ensembl NCBI MGI UniProt Show fit	serine and arginine-rich splicing factor 3
chr1_-_125362321 Show fit	4.73	ENSMUST00000191544.7	Actr3 Links Ensembl NCBI MGI UniProt Show fit	ARP3 actin-related protein 3
chr18_+_36661198 Show fit	4.72	ENSMUST00000237174.2 ENSMUST00000236124.2 ENSMUST00000236779.2 ENSMUST00000235181.2 ENSMUST00000074298.13 ENSMUST00000115694.3 ENSMUST00000236126.2	Slc4a9 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr6_-_87649173 Show fit	4.66	ENSMUST00000032130.8	Aplf Links Ensembl NCBI MGI UniProt Show fit	aprataxin and PNKP like factor
chr10_-_40178182 Show fit	4.64	ENSMUST00000099945.6 ENSMUST00000238953.2 ENSMUST00000238969.2	Amd1 Links Ensembl NCBI MGI UniProt Show fit	S-adenosylmethionine decarboxylase 1
chr12_+_102521225 Show fit	4.59	ENSMUST00000021610.7	Chga Links Ensembl NCBI MGI UniProt Show fit	chromogranin A
chr6_-_112673565 Show fit	4.57	ENSMUST00000113182.8 ENSMUST00000113180.8 ENSMUST00000068487.12 ENSMUST00000077088.11	Rad18 Links Ensembl NCBI MGI UniProt Show fit	RAD18 E3 ubiquitin protein ligase
chrX_+_73314418 Show fit	4.57	ENSMUST00000008826.14 ENSMUST00000151702.8 ENSMUST00000074085.12 ENSMUST00000135690.2	Rpl10 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L10
chr6_-_87649124 Show fit	4.49	ENSMUST00000065997.5	Aplf Links Ensembl NCBI MGI UniProt Show fit	aprataxin and PNKP like factor
chr4_+_63478478 Show fit	4.48	ENSMUST00000080336.4	Tmem268 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 268
chr5_+_33176160 Show fit	4.43	ENSMUST00000019109.8	Ywhah Links Ensembl NCBI MGI UniProt Show fit	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr11_+_85202990 Show fit	4.43	ENSMUST00000127717.2	Ppm1d Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1D magnesium-dependent, delta isoform
chr17_-_34000804 Show fit	4.40	ENSMUST00000002360.17	Angptl4 Links Ensembl NCBI MGI UniProt Show fit	angiopoietin-like 4
chr11_-_100012384 Show fit	4.40	ENSMUST00000007275.3	Krt13 Links Ensembl NCBI MGI UniProt Show fit	keratin 13
chr9_-_67739607 Show fit	4.35	ENSMUST00000054500.7	C2cd4a Links Ensembl NCBI MGI UniProt Show fit	C2 calcium-dependent domain containing 4A
chr1_-_154975376 Show fit	4.33	ENSMUST00000055322.6	Ier5 Links Ensembl NCBI MGI UniProt Show fit	immediate early response 5
chr2_-_62313981 Show fit	4.29	ENSMUST00000136686.2 ENSMUST00000102733.10	Gcg Links Ensembl NCBI MGI UniProt Show fit	glucagon
chr6_-_34294377 Show fit	4.19	ENSMUST00000154655.2 ENSMUST00000102980.11	Akr1b3 Links Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member B3 (aldose reductase)
chr13_-_23946359 Show fit	4.10	ENSMUST00000091701.3	H3c1 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 1
chr13_+_23947641 Show fit	4.08	ENSMUST00000055770.4	H1f1 Links Ensembl NCBI MGI UniProt Show fit	H1.1 linker histone, cluster member
chr19_+_39102342 Show fit	4.03	ENSMUST00000087234.3	Cyp2c66 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 66
chr13_-_21967540 Show fit	3.98	ENSMUST00000189457.2	H3c11 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 11
chr8_-_85696040 Show fit	3.96	ENSMUST00000214133.2 ENSMUST00000147812.8	Gm49661 Links Ensembl NCBI MGI UniProt Show fit Rnaseh2a Links Ensembl NCBI MGI UniProt Show fit	predicted gene, 49661 ribonuclease H2, large subunit
chr10_+_79613083 Show fit	3.88	ENSMUST00000020575.5	Fstl3 Links Ensembl NCBI MGI UniProt Show fit	follistatin-like 3
chr19_-_3464447 Show fit	3.83	ENSMUST00000025842.8 ENSMUST00000237521.2	Gal Links Ensembl NCBI MGI UniProt Show fit	galanin and GMAP prepropeptide
chr4_-_119515978 Show fit	3.78	ENSMUST00000106309.9 ENSMUST00000044426.8	Guca2b Links Ensembl NCBI MGI UniProt Show fit	guanylate cyclase activator 2b (retina)
chr13_+_95460110 Show fit	3.78	ENSMUST00000221807.2	Zbed3 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, BED type containing 3
chr6_-_72416531 Show fit	3.76	ENSMUST00000205335.2 ENSMUST00000206692.2 ENSMUST00000059472.10	Mat2a Links Ensembl NCBI MGI UniProt Show fit	methionine adenosyltransferase II, alpha
chr11_+_62442502 Show fit	3.66	ENSMUST00000136938.2	Ubb Links Ensembl NCBI MGI UniProt Show fit	ubiquitin B
chr4_-_116485118 Show fit	3.56	ENSMUST00000030456.14	Nasp Links Ensembl NCBI MGI UniProt Show fit	nuclear autoantigenic sperm protein (histone-binding)
chr13_-_23929490 Show fit	3.44	ENSMUST00000091752.5	H3c3 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 3
chr14_+_69846517 Show fit	3.36	ENSMUST00000022660.14	Loxl2 Links Ensembl NCBI MGI UniProt Show fit	lysyl oxidase-like 2
chr8_+_108162985 Show fit	3.32	ENSMUST00000166615.3 ENSMUST00000213097.2 ENSMUST00000212205.2	Wwp2 Links Ensembl NCBI MGI UniProt Show fit	WW domain containing E3 ubiquitin protein ligase 2
chr11_-_100026754 Show fit	3.32	ENSMUST00000107411.3	Krt15 Links Ensembl NCBI MGI UniProt Show fit	keratin 15
chr14_-_57015748 Show fit	3.13	ENSMUST00000022507.13 ENSMUST00000163924.2	Pspc1 Links Ensembl NCBI MGI UniProt Show fit	paraspeckle protein 1
chrX_+_72818003 Show fit	3.12	ENSMUST00000002081.6	Srpk3 Links Ensembl NCBI MGI UniProt Show fit	serine/arginine-rich protein specific kinase 3
chr13_-_73848807 Show fit	3.10	ENSMUST00000022048.6	Slc6a19 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter), member 19
chr15_+_6673167 Show fit	3.06	ENSMUST00000163073.2	Fyb Links Ensembl NCBI MGI UniProt Show fit	FYN binding protein
chr11_+_120489358 Show fit	2.98	ENSMUST00000093140.5	Anapc11 Links Ensembl NCBI MGI UniProt Show fit	anaphase promoting complex subunit 11
chr2_+_128942900 Show fit	2.93	ENSMUST00000103205.11	Polr1b Links Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) I polypeptide B
chr6_-_67512768 Show fit	2.91	ENSMUST00000058178.6	Tacstd2 Links Ensembl NCBI MGI UniProt Show fit	tumor-associated calcium signal transducer 2
chr8_-_84467798 Show fit	2.88	ENSMUST00000075843.13 ENSMUST00000109802.3 ENSMUST00000166939.8 ENSMUST00000002964.14	Adgre5 Links Ensembl NCBI MGI UniProt Show fit	adhesion G protein-coupled receptor E5
chrX_+_158623460 Show fit	2.87	ENSMUST00000112451.8 ENSMUST00000112453.9	Sh3kbp1 Links Ensembl NCBI MGI UniProt Show fit	SH3-domain kinase binding protein 1
chr7_-_34089109 Show fit	2.86	ENSMUST00000085585.12	Lsm14a Links Ensembl NCBI MGI UniProt Show fit	LSM14A mRNA processing body assembly factor
chr13_-_23806530 Show fit	2.82	ENSMUST00000062045.4	H1f4 Links Ensembl NCBI MGI UniProt Show fit	H1.4 linker histone, cluster member
chr6_-_4747066 Show fit	2.81	ENSMUST00000090686.11 ENSMUST00000133306.8	Sgce Links Ensembl NCBI MGI UniProt Show fit	sarcoglycan, epsilon
chr14_-_51045182 Show fit	2.81	ENSMUST00000227614.2	Ccnb1ip1 Links Ensembl NCBI MGI UniProt Show fit	cyclin B1 interacting protein 1
chr4_+_133097013 Show fit	2.81	ENSMUST00000030669.8	Slc9a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr6_+_4747356 Show fit	2.78	ENSMUST00000176551.3	Peg10 Links Ensembl NCBI MGI UniProt Show fit	paternally expressed 10
chr15_-_101389384 Show fit	2.76	ENSMUST00000023718.9	Krt83 Links Ensembl NCBI MGI UniProt Show fit	keratin 83
chr2_+_128942919 Show fit	2.74	ENSMUST00000028874.8	Polr1b Links Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) I polypeptide B
chr11_-_120489172 Show fit	2.71	ENSMUST00000026125.3	Alyref Links Ensembl NCBI MGI UniProt Show fit	Aly/REF export factor
chr13_-_23755374 Show fit	2.69	ENSMUST00000102969.6	H2ac8 Links Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 8
chr6_+_5390386 Show fit	2.62	ENSMUST00000183358.2	Asb4 Links Ensembl NCBI MGI UniProt Show fit	ankyrin repeat and SOCS box-containing 4
chr12_+_85520652 Show fit	2.60	ENSMUST00000021674.7	Fos Links Ensembl NCBI MGI UniProt Show fit	FBJ osteosarcoma oncogene
chr3_+_103739877 Show fit	2.59	ENSMUST00000062945.12	Bcl2l15 Links Ensembl NCBI MGI UniProt Show fit	BCLl2-like 15
chr15_-_101602734 Show fit	2.58	ENSMUST00000023788.8	Krt6a Links Ensembl NCBI MGI UniProt Show fit	keratin 6A
chr15_+_91722524 Show fit	2.57	ENSMUST00000109276.8 ENSMUST00000088555.10 ENSMUST00000100293.9 ENSMUST00000126508.8 ENSMUST00000239545.1	Smgc Links Ensembl NCBI MGI UniProt Show fit ENSMUSG00000118670.1 Links Ensembl NCBI MGI UniProt Show fit	submandibular gland protein C mucin 19
chr11_+_6510167 Show fit	2.55	ENSMUST00000109722.9	Ccm2 Links Ensembl NCBI MGI UniProt Show fit	cerebral cavernous malformation 2
chr13_+_23936250 Show fit	2.54	ENSMUST00000091703.3	H3c2 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 2
chr18_-_35855383 Show fit	2.47	ENSMUST00000133064.8	Ecscr Links Ensembl NCBI MGI UniProt Show fit	endothelial cell surface expressed chemotaxis and apoptosis regulator
chr16_-_92196954 Show fit	2.38	ENSMUST00000023672.10	Rcan1 Links Ensembl NCBI MGI UniProt Show fit	regulator of calcineurin 1
chr8_-_85696369 Show fit	2.34	ENSMUST00000109736.9 ENSMUST00000140561.8	Rnaseh2a Links Ensembl NCBI MGI UniProt Show fit	ribonuclease H2, large subunit
chr11_+_62441992 Show fit	2.31	ENSMUST00000019649.4	Ubb Links Ensembl NCBI MGI UniProt Show fit	ubiquitin B
chr7_-_30312246 Show fit	2.27	ENSMUST00000006476.6	Upk1a Links Ensembl NCBI MGI UniProt Show fit	uroplakin 1A
chr18_-_34757653 Show fit	2.27	ENSMUST00000003876.10 ENSMUST00000115766.8 ENSMUST00000097626.10 ENSMUST00000115765.2	Brd8 Links Ensembl NCBI MGI UniProt Show fit	bromodomain containing 8
chr7_-_140846328 Show fit	2.26	ENSMUST00000106023.8 ENSMUST00000097952.9 ENSMUST00000026571.11	Irf7 Links Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 7
chr7_-_141241632 Show fit	2.26	ENSMUST00000239500.1	ENSMUSG00000118661.1 Links Ensembl NCBI MGI UniProt Show fit	mucin 6, gastric
chr19_+_60744385 Show fit	2.25	ENSMUST00000088237.6	Nanos1 Links Ensembl NCBI MGI UniProt Show fit	nanos C2HC-type zinc finger 1
chr19_-_40982576 Show fit	2.23	ENSMUST00000117695.8	Blnk Links Ensembl NCBI MGI UniProt Show fit	B cell linker
chr15_-_101621332 Show fit	2.22	ENSMUST00000023709.7	Krt5 Links Ensembl NCBI MGI UniProt Show fit	keratin 5
chr17_+_29587930 Show fit	2.12	ENSMUST00000137644.3	Fgd2 Links Ensembl NCBI MGI UniProt Show fit	FYVE, RhoGEF and PH domain containing 2
chr9_-_70564403 Show fit	2.10	ENSMUST00000213380.2 ENSMUST00000049031.6	Mindy2 Links Ensembl NCBI MGI UniProt Show fit	MINDY lysine 48 deubiquitinase 2
chr6_-_78355834 Show fit	2.08	ENSMUST00000089667.8 ENSMUST00000167492.4	Reg3d Links Ensembl NCBI MGI UniProt Show fit	regenerating islet-derived 3 delta
chr8_+_124138163 Show fit	2.08	ENSMUST00000071134.4 ENSMUST00000212743.2	Tubb3 Links Ensembl NCBI MGI UniProt Show fit	tubulin, beta 3 class III
chr2_-_93787441 Show fit	2.07	ENSMUST00000099689.5	Gm13889 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 13889
chr13_+_23759930 Show fit	2.05	ENSMUST00000105105.4	H3c4 Links Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 4
chr17_+_34174782 Show fit	2.05	ENSMUST00000025178.17	Vps52 Links Ensembl NCBI MGI UniProt Show fit	VPS52 GARP complex subunit
chr14_-_50479161 Show fit	1.98	ENSMUST00000214388.2	Olfr731 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 731
chr17_-_14914484 Show fit	1.93	ENSMUST00000170872.3	Thbs2 Links Ensembl NCBI MGI UniProt Show fit	thrombospondin 2
chr15_-_98380567 Show fit	1.92	ENSMUST00000023726.5	Lalba Links Ensembl NCBI MGI UniProt Show fit	lactalbumin, alpha
chr1_-_36312482 Show fit	1.92	ENSMUST00000056946.8	Neurl3 Links Ensembl NCBI MGI UniProt Show fit	neuralized E3 ubiquitin protein ligase 3
chr10_+_87926932 Show fit	1.91	ENSMUST00000048621.8	Pmch Links Ensembl NCBI MGI UniProt Show fit	pro-melanin-concentrating hormone
chr4_+_150572847 Show fit	1.86	ENSMUST00000105680.9	Rere Links Ensembl NCBI MGI UniProt Show fit	arginine glutamic acid dipeptide (RE) repeats
chr3_-_92393193 Show fit	1.84	ENSMUST00000054599.8	Sprr1a Links Ensembl NCBI MGI UniProt Show fit	small proline-rich protein 1A
chr10_-_79744726 Show fit	1.83	ENSMUST00000165684.8 ENSMUST00000164705.8 ENSMUST00000105378.9 ENSMUST00000170409.2	Med16 Links Ensembl NCBI MGI UniProt Show fit	mediator complex subunit 16

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View png image

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.5	43.4	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
12.4	62.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
11.2	33.6	GO:0002148	hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
7.5	37.3	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
7.2	21.5	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
5.0	59.7	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536)
4.6	13.9	GO:0060722	spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
4.4	17.6	GO:0036233	proline transmembrane transport(GO:0035524) glycine import(GO:0036233)
4.2	12.5	GO:0006597	spermine biosynthetic process(GO:0006597)
3.8	11.3	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
3.5	21.3	GO:0071918	urea transmembrane transport(GO:0071918)
3.2	6.3	GO:0006407	rRNA export from nucleus(GO:0006407)
3.1	27.8	GO:0006776	vitamin A metabolic process(GO:0006776)
2.9	14.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
2.7	13.6	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
2.7	21.4	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
2.5	10.0	GO:0021941	negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
2.4	19.4	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
2.2	6.7	GO:0052055	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
2.2	17.8	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) regulation of chaperone-mediated autophagy(GO:1904714)
2.1	20.6	GO:0070944	neutrophil mediated killing of bacterium(GO:0070944)
2.0	49.9	GO:0000028	ribosomal small subunit assembly(GO:0000028)
1.5	4.4	GO:0006713	glucocorticoid catabolic process(GO:0006713)
1.5	8.7	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.4	5.7	GO:0017126	nucleologenesis(GO:0017126)
1.4	4.2	GO:0090420	hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
1.3	9.2	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
1.3	11.4	GO:0015671	oxygen transport(GO:0015671)
1.3	29.0	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
1.2	3.7	GO:0007439	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
1.1	4.6	GO:1901079	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) regulation of dense core granule biogenesis(GO:2000705)
1.1	7.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
1.1	24.5	GO:0000920	cell separation after cytokinesis(GO:0000920)
1.1	6.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
1.0	1.9	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.0	7.7	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0	3.8	GO:0051795	positive regulation of catagen(GO:0051795)
0.9	4.7	GO:1904171	negative regulation of bleb assembly(GO:1904171)
0.9	2.8	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.9	6.0	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.8	26.9	GO:0019731	antibacterial humoral response(GO:0019731)
0.8	8.7	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.8	7.9	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.8	6.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.8	6.1	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.8	8.3	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7	2.2	GO:0098749	cerebellar neuron development(GO:0098749)
0.7	4.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.7	5.0	GO:0019371	cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.7	7.2	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.6	11.5	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.6	3.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.6	4.9	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.6	2.9	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.6	9.9	GO:0032096	negative regulation of response to food(GO:0032096)
0.5	7.0	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.5	4.8	GO:0030035	microspike assembly(GO:0030035)
0.5	5.8	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.5	5.6	GO:0032275	luteinizing hormone secretion(GO:0032275)
0.5	1.5	GO:0071288	cellular response to mercury ion(GO:0071288)
0.5	1.9	GO:0046351	disaccharide biosynthetic process(GO:0046351)
0.5	1.4	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.5	76.4	GO:0007586	digestion(GO:0007586)
0.5	1.9	GO:0021699	cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.5	9.5	GO:0044243	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.4	4.3	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.4	12.1	GO:0045109	intermediate filament organization(GO:0045109)
0.4	8.8	GO:0060213	dentate gyrus development(GO:0021542) regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.4	12.7	GO:0044381	glucose import in response to insulin stimulus(GO:0044381)
0.4	7.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.4	1.5	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.4	2.3	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.4	1.1	GO:1903487	regulation of lactation(GO:1903487)
0.4	12.9	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.3	7.0	GO:0030049	muscle filament sliding(GO:0030049)
0.3	7.2	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.3	15.3	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.3	3.3	GO:0007021	tubulin complex assembly(GO:0007021)
0.3	4.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.3	0.5	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.3	12.2	GO:0030225	macrophage differentiation(GO:0030225)
0.3	1.0	GO:0070384	Harderian gland development(GO:0070384)
0.3	3.9	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.2	2.6	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.2	5.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.2	1.8	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	8.3	GO:0051290	protein heterotetramerization(GO:0051290)
0.2	2.8	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.2	2.6	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.2	1.0	GO:0031509	telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.2	14.2	GO:0002181	cytoplasmic translation(GO:0002181)
0.2	0.7	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
0.2	22.3	GO:0043627	response to estrogen(GO:0043627)
0.2	1.0	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) regulation of ovarian follicle development(GO:2000354)
0.2	0.3	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.1	5.8	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.1	0.3	GO:1902623	response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of monocyte chemotaxis(GO:0090027) regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of neutrophil migration(GO:1902623)
0.1	2.3	GO:0051026	chiasma assembly(GO:0051026)
0.1	0.4	GO:1901561	cellular response to benomyl(GO:0072755) response to benomyl(GO:1901561)
0.1	1.5	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	2.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.9	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	1.8	GO:2000018	regulation of male gonad development(GO:2000018)
0.1	8.5	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1	1.2	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	3.0	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.8	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	2.5	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	0.5	GO:0035747	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1	0.3	GO:2000422	T-helper 1 cell lineage commitment(GO:0002296) regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.1	0.5	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	2.4	GO:0007614	short-term memory(GO:0007614) locomotion involved in locomotory behavior(GO:0031987)
0.1	1.1	GO:0042255	ribosome assembly(GO:0042255)
0.1	0.6	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	3.4	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.1	2.4	GO:0035994	response to muscle stretch(GO:0035994)
0.1	9.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	0.7	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.1	1.7	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	1.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	0.2	GO:0042414	epinephrine metabolic process(GO:0042414)
0.1	3.1	GO:0015804	neutral amino acid transport(GO:0015804)
0.1	3.3	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	1.6	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.1	2.8	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.1	0.7	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1	0.6	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	7.9	GO:0050684	regulation of mRNA processing(GO:0050684)
0.1	0.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	2.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	2.2	GO:0018149	peptide cross-linking(GO:0018149)
0.1	1.0	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	1.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	4.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	3.8	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.4	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.2	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0	3.1	GO:0045576	mast cell activation(GO:0045576)
0.0	0.2	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	1.8	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	6.9	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	2.7	GO:0051028	mRNA transport(GO:0051028)
0.0	2.9	GO:0008360	regulation of cell shape(GO:0008360)
0.0	2.3	GO:0051453	regulation of intracellular pH(GO:0051453)
0.0	2.8	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.0	2.5	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0	0.6	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.2	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.0	2.9	GO:0060048	cardiac muscle contraction(GO:0060048)
0.0	3.6	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.4	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	11.0	GO:0030036	actin cytoskeleton organization(GO:0030036)
0.0	0.4	GO:0021591	ventricular system development(GO:0021591)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.3	41.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
4.1	57.0	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
2.9	11.4	GO:0005833	hemoglobin complex(GO:0005833)
2.6	7.9	GO:0042643	actomyosin, actin portion(GO:0042643)
2.6	7.7	GO:0005584	collagen type I trimer(GO:0005584)
2.2	17.8	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
2.0	33.6	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.8	19.4	GO:0045098	type III intermediate filament(GO:0045098)
1.4	21.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
1.3	3.8	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
1.2	39.9	GO:0005680	anaphase-promoting complex(GO:0005680)
1.2	71.2	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
1.1	6.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.0	4.2	GO:0097454	Schwann cell microvillus(GO:0097454)
1.0	4.8	GO:0044393	microspike(GO:0044393)
0.9	7.4	GO:0001652	granular component(GO:0001652)
0.9	8.9	GO:0042382	paraspeckles(GO:0042382)
0.9	9.5	GO:0005796	Golgi lumen(GO:0005796)
0.8	7.6	GO:0016012	sarcoglycan complex(GO:0016012)
0.8	4.9	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.8	4.6	GO:0042583	chromaffin granule(GO:0042583)
0.8	6.8	GO:0045298	tubulin complex(GO:0045298)
0.8	12.8	GO:0001939	female pronucleus(GO:0001939)
0.7	3.7	GO:0000938	GARP complex(GO:0000938) EARP complex(GO:1990745)
0.7	6.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.7	12.7	GO:0032593	insulin-responsive compartment(GO:0032593)
0.6	7.0	GO:0032982	myosin filament(GO:0032982)
0.5	7.4	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.5	2.6	GO:0035976	AP1 complex(GO:0035976)
0.4	2.6	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4	4.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.3	5.6	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3	8.7	GO:0005859	muscle myosin complex(GO:0005859)
0.3	8.7	GO:0010369	chromocenter(GO:0010369)
0.3	13.7	GO:0035861	site of double-strand break(GO:0035861)
0.3	24.5	GO:0005871	kinesin complex(GO:0005871)
0.3	1.5	GO:0031310	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3	23.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.3	5.3	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.3	20.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.2	4.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.2	1.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.2	2.8	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.2	0.6	GO:0071007	U2-type catalytic step 2 spliceosome(GO:0071007)
0.2	11.5	GO:0005876	spindle microtubule(GO:0005876)
0.2	5.8	GO:0042588	zymogen granule(GO:0042588)
0.2	52.2	GO:0043209	myelin sheath(GO:0043209)
0.2	2.3	GO:0000812	Swr1 complex(GO:0000812)
0.1	0.9	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	1.4	GO:0016272	prefoldin complex(GO:0016272)
0.1	1.0	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	65.2	GO:0031012	extracellular matrix(GO:0031012)
0.1	1.0	GO:0031595	nuclear proteasome complex(GO:0031595)
0.1	9.0	GO:0005882	intermediate filament(GO:0005882)
0.1	24.3	GO:0000793	condensed chromosome(GO:0000793)
0.1	1.0	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	1.1	GO:0045120	pronucleus(GO:0045120)
0.1	8.0	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	2.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	5.0	GO:0016459	myosin complex(GO:0016459)
0.0	16.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	2.6	GO:0031526	brush border membrane(GO:0031526)
0.0	10.7	GO:0030659	cytoplasmic vesicle membrane(GO:0030659)
0.0	0.7	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.7	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	16.0	GO:0005774	vacuolar membrane(GO:0005774)
0.0	1.8	GO:0016592	mediator complex(GO:0016592)
0.0	14.7	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	2.1	GO:0014704	intercalated disc(GO:0014704)
0.0	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.7	GO:0031672	A band(GO:0031672)
0.0	0.9	GO:0001533	cornified envelope(GO:0001533)
0.0	30.9	GO:0005730	nucleolus(GO:0005730)
0.0	1.4	GO:0001772	immunological synapse(GO:0001772)
0.0	2.2	GO:0030139	endocytic vesicle(GO:0030139)
0.0	0.0	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.0	3.8	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	2.1	GO:0005769	early endosome(GO:0005769)
0.0	3.0	GO:0016607	nuclear speck(GO:0016607)
0.0	2.1	GO:0016324	apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.8	59.1	GO:0031721	hemoglobin alpha binding(GO:0031721)
11.3	11.3	GO:0015254	glycerol channel activity(GO:0015254)
9.5	57.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
5.9	17.6	GO:0005302	L-tyrosine transmembrane transporter activity(GO:0005302)
5.4	26.9	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
5.4	42.9	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
4.0	59.7	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
3.4	13.6	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
3.3	10.0	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
3.3	39.2	GO:0008061	chitin binding(GO:0008061)
3.2	19.4	GO:1990254	keratin filament binding(GO:1990254)
3.0	21.3	GO:0015265	urea channel activity(GO:0015265)
2.5	7.6	GO:0001847	opsonin receptor activity(GO:0001847)
1.9	5.6	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
1.8	12.5	GO:0019808	polyamine binding(GO:0019808)
1.8	8.8	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
1.3	24.2	GO:0016918	retinal binding(GO:0016918)
1.2	8.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.9	3.8	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.9	6.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.9	4.4	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.8	6.7	GO:0001849	complement component C1q binding(GO:0001849)
0.8	31.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.8	23.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.7	1.5	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.7	38.3	GO:0004601	peroxidase activity(GO:0004601)
0.7	37.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.7	6.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.7	34.3	GO:0003785	actin monomer binding(GO:0003785)
0.6	1.9	GO:0004461	lactose synthase activity(GO:0004461)
0.6	3.8	GO:0004966	galanin receptor activity(GO:0004966)
0.6	3.8	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.6	4.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6	126.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.6	4.6	GO:0000403	Y-form DNA binding(GO:0000403)
0.6	7.4	GO:0001054	RNA polymerase I activity(GO:0001054)
0.6	3.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.6	8.3	GO:0008097	5S rRNA binding(GO:0008097)
0.5	22.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.5	2.1	GO:0071796	K6-linked polyubiquitin binding(GO:0071796)
0.5	2.4	GO:0030280	structural constituent of epidermis(GO:0030280)
0.5	9.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.5	7.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5	7.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.4	8.7	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.4	4.8	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.4	27.1	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.3	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.3	5.1	GO:0051525	NFAT protein binding(GO:0051525)
0.3	2.8	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.3	1.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	8.6	GO:0008236	serine-type peptidase activity(GO:0008236)
0.3	2.4	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3	48.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.3	3.9	GO:0048185	activin binding(GO:0048185)
0.2	6.3	GO:0070628	proteasome binding(GO:0070628)
0.2	1.8	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.2	7.0	GO:0000146	microfilament motor activity(GO:0000146)
0.2	0.2	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.2	24.5	GO:0003777	microtubule motor activity(GO:0003777)
0.2	5.9	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2	15.5	GO:0005507	copper ion binding(GO:0005507)
0.2	5.3	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2	12.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	0.7	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.2	2.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	5.9	GO:0017025	TBP-class protein binding(GO:0017025)
0.2	23.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	0.5	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.2	8.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.2	6.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	2.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.9	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	0.5	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	18.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	4.8	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	4.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.7	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	2.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	1.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.1	7.9	GO:0017022	myosin binding(GO:0017022)
0.1	6.7	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	0.3	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.1	16.5	GO:0008017	microtubule binding(GO:0008017)
0.1	0.3	GO:0048495	Roundabout binding(GO:0048495)
0.1	1.0	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	3.1	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.1	1.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.5	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	3.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	1.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.6	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	8.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	2.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	5.5	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	2.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	2.5	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	2.5	GO:0051087	chaperone binding(GO:0051087)
0.0	6.2	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.5	GO:0005123	death receptor binding(GO:0005123)
0.0	0.7	GO:0071949	FAD binding(GO:0071949)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.1	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	2.6	GO:1901981	phosphatidylinositol phosphate binding(GO:1901981)
0.0	0.0	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0	1.8	GO:0002020	protease binding(GO:0002020)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	2.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.6	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	50.1	PID AURORA B PATHWAY	Aurora B signaling
0.7	57.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.6	33.6	PID IL23 PATHWAY	IL23-mediated signaling events
0.5	17.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.5	17.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	44.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.4	9.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	82.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3	7.7	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.3	33.0	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.3	15.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	15.2	PID BMP PATHWAY	BMP receptor signaling
0.2	6.1	PID ALK1 PATHWAY	ALK1 signaling events
0.2	7.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	17.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.2	9.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	11.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	2.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	2.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	2.8	PID RHOA PATHWAY	RhoA signaling pathway
0.1	4.4	PID P53 REGULATION PATHWAY	p53 pathway
0.1	1.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	1.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	1.6	PID BARD1 PATHWAY	BARD1 signaling events
0.1	8.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	1.9	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	2.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	3.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	3.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	3.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	57.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
1.6	26.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
1.3	39.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
1.1	71.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.8	11.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.8	24.5	REACTOME KINESINS	Genes involved in Kinesins
0.7	15.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.6	41.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.6	21.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.6	5.7	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.5	8.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5	6.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.5	7.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.4	15.7	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.3	17.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	4.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	20.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	5.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.2	11.2	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2	4.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	2.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	5.7	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.2	11.1	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.2	14.4	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.2	6.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2	2.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	1.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	2.7	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.2	4.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	2.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	8.3	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.1	35.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	3.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	2.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	3.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.7	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	2.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	6.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	3.8	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	1.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	2.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway