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GSE58827: Dynamics of the Mouse Liver

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Results for Tcf3

Z-value: 1.59

Motif logo

Transcription factors associated with Tcf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000020167.15 transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf3mm39_v1_chr10_-_80269436_802694880.728.4e-07Click!

Activity profile of Tcf3 motif

Sorted Z-values of Tcf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_112417633 19.57 ENSMUST00000034435.7
chymotrypsinogen B1
chr2_+_131028861 16.81 ENSMUST00000028804.15
ENSMUST00000079857.9
cell division cycle 25B
chr7_-_142223662 16.68 ENSMUST00000228850.2
predicted gene, 49394
chr6_+_30639217 16.49 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr6_-_41291634 15.05 ENSMUST00000064324.12
trypsin 5
chr2_-_28453374 13.34 ENSMUST00000028161.6
carboxyl ester lipase
chr11_-_102255999 12.72 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr6_+_29694181 12.23 ENSMUST00000046750.14
ENSMUST00000115250.4
tetraspanin 33
chr8_+_23629080 11.74 ENSMUST00000033947.15
ankyrin 1, erythroid
chr8_-_106660470 11.64 ENSMUST00000034368.8
chymotrypsin-like
chr6_-_41354538 11.42 ENSMUST00000096003.7
protease, serine 3
chr12_+_109425769 11.26 ENSMUST00000173812.2
delta like non-canonical Notch ligand 1
chr17_-_26420300 10.90 ENSMUST00000025019.9
Rho GDP dissociation inhibitor (GDI) gamma
chr3_-_20329823 10.71 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr6_-_41423004 8.94 ENSMUST00000095999.7
predicted gene 10334
chr6_+_41435846 8.80 ENSMUST00000031910.8
protease, serine 1 (trypsin 1)
chr6_+_41369290 8.58 ENSMUST00000049079.9
predicted gene 5771
chr7_+_44866635 8.58 ENSMUST00000097216.5
ENSMUST00000209343.2
ENSMUST00000209678.2
TEA domain family member 2
chr17_-_26420332 8.44 ENSMUST00000121959.3
Rho GDP dissociation inhibitor (GDI) gamma
chr8_+_23629046 8.42 ENSMUST00000121075.8
ankyrin 1, erythroid
chr19_-_15901919 8.38 ENSMUST00000162053.8
phosphoserine aminotransferase 1
chr13_-_55676334 7.86 ENSMUST00000047877.5
docking protein 3
chr1_-_75482975 7.38 ENSMUST00000113567.10
ENSMUST00000113565.3
obscurin-like 1
chr4_-_43523388 7.21 ENSMUST00000107913.10
ENSMUST00000030184.12
tropomyosin 2, beta
chr8_+_95703728 7.13 ENSMUST00000179619.9
adhesion G protein-coupled receptor G1
chr9_-_21874802 7.12 ENSMUST00000006397.7
erythropoietin receptor
chr4_-_133600308 6.97 ENSMUST00000137486.3
ribosomal protein S6 kinase polypeptide 1
chr4_-_43523595 6.29 ENSMUST00000107914.10
tropomyosin 2, beta
chr3_-_100396635 6.29 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr6_+_41331039 6.15 ENSMUST00000072103.7
trypsin 10
chr11_+_115790768 6.12 ENSMUST00000152171.8
small integral membrane protein 5
chrX_-_138772383 5.80 ENSMUST00000033811.14
ENSMUST00000087401.12
microrchidia 4
chr11_+_53410697 5.63 ENSMUST00000120878.9
ENSMUST00000147912.2
septin 8
chr5_+_123214332 5.63 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr4_+_140737955 5.29 ENSMUST00000071977.9
microfibrillar-associated protein 2
chr10_+_128745214 5.14 ENSMUST00000220308.2
CD63 antigen
chr8_+_3715747 5.11 ENSMUST00000014118.4
mast cell expressed membrane protein 1
chr4_-_43523745 5.03 ENSMUST00000150592.2
tropomyosin 2, beta
chr5_-_113968483 5.02 ENSMUST00000100874.6
selectin, platelet (p-selectin) ligand
chr18_+_34973605 4.98 ENSMUST00000043484.8
receptor accessory protein 2
chr2_+_103800553 4.77 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr11_+_104468107 4.68 ENSMUST00000106956.10
myosin, light polypeptide 4
chr2_+_103800459 4.54 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr11_-_46203047 4.49 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr7_+_141995545 4.47 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr7_-_16790594 4.46 ENSMUST00000037762.11
hypoxia inducible factor 3, alpha subunit
chr2_+_84564394 4.42 ENSMUST00000238573.2
ENSMUST00000090729.9
yippee like 4
chr11_+_115790951 4.40 ENSMUST00000142089.2
ENSMUST00000131566.2
small integral membrane protein 5
chr11_+_104467791 4.38 ENSMUST00000106957.8
myosin, light polypeptide 4
chr1_-_167221344 4.24 ENSMUST00000028005.3
microsomal glutathione S-transferase 3
chr7_+_142025817 4.22 ENSMUST00000105966.2
lymphocyte specific 1
chr7_+_142025575 4.16 ENSMUST00000038946.9
lymphocyte specific 1
chrX_+_70599524 4.08 ENSMUST00000072699.13
ENSMUST00000114582.9
ENSMUST00000015361.11
ENSMUST00000088874.10
high mobility group box 3
chr11_+_11636213 3.99 ENSMUST00000076700.11
ENSMUST00000048122.13
IKAROS family zinc finger 1
chr9_-_107863062 3.98 ENSMUST00000048568.6
inka box actin regulator 1
chr4_-_133694607 3.93 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr6_-_39397334 3.92 ENSMUST00000031985.13
makorin, ring finger protein, 1
chr4_-_133599616 3.91 ENSMUST00000157067.9
ribosomal protein S6 kinase polypeptide 1
chr11_-_69496655 3.82 ENSMUST00000047889.13
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr3_+_95496270 3.80 ENSMUST00000176674.8
ENSMUST00000177389.8
ENSMUST00000176755.8
ENSMUST00000177399.2
golgi phosphoprotein 3-like
chr14_+_70694887 3.79 ENSMUST00000003561.10
phytanoyl-CoA hydroxylase interacting protein
chr8_+_95720864 3.75 ENSMUST00000212141.2
adhesion G protein-coupled receptor G1
chr11_+_61847589 3.67 ENSMUST00000201671.4
ENSMUST00000202178.4
sperm antigen with calponin homology and coiled-coil domains 1
chr15_+_78810919 3.67 ENSMUST00000089377.6
lectin, galactose binding, soluble 1
chr3_+_95496239 3.65 ENSMUST00000177390.8
ENSMUST00000060323.12
ENSMUST00000098861.11
golgi phosphoprotein 3-like
chr8_-_123425805 3.63 ENSMUST00000127984.9
CBFA2/RUNX1 translocation partner 3
chr7_+_27259895 3.56 ENSMUST00000187032.2
RIKEN cDNA 2310022A10 gene
chr7_+_121888520 3.54 ENSMUST00000064989.12
ENSMUST00000064921.5
protein kinase C, beta
chr1_-_171061838 3.49 ENSMUST00000193973.2
Fc receptor, IgE, high affinity I, gamma polypeptide
chr1_+_135060431 3.48 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr4_-_133694543 3.46 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr8_+_95703506 3.39 ENSMUST00000212581.2
adhesion G protein-coupled receptor G1
chr8_+_95721019 3.32 ENSMUST00000212976.2
ENSMUST00000212995.2
adhesion G protein-coupled receptor G1
chrX_-_47551990 3.27 ENSMUST00000033429.9
ENSMUST00000140486.2
E74-like factor 4 (ets domain transcription factor)
chr19_+_5118103 3.27 ENSMUST00000070630.8
CD248 antigen, endosialin
chr7_+_19024994 3.26 ENSMUST00000108468.5
reticulon 2 (Z-band associated protein)
chr3_+_146110387 3.18 ENSMUST00000106151.8
ENSMUST00000106153.9
ENSMUST00000039021.11
ENSMUST00000106149.8
ENSMUST00000149262.8
synovial sarcoma, X 2 interacting protein
chr11_+_32155415 3.17 ENSMUST00000039601.10
ENSMUST00000149043.3
small nuclear ribonucleoprotein 25 (U11/U12)
chr8_+_46338498 3.12 ENSMUST00000034053.7
PDZ and LIM domain 3
chr8_-_123187406 3.12 ENSMUST00000006762.7
snail family zinc finger 3
chrX_-_149595711 3.12 ENSMUST00000112697.10
MAGE family member D2
chr13_+_97377604 3.03 ENSMUST00000041623.9
ectodermal-neural cortex 1
chr11_+_76889415 3.02 ENSMUST00000108402.9
ENSMUST00000021195.11
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr2_-_113883285 3.01 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr3_-_151871867 2.99 ENSMUST00000046614.10
GIPC PDZ domain containing family, member 2
chr2_+_130119077 2.98 ENSMUST00000028890.15
ENSMUST00000159373.2
NOP56 ribonucleoprotein
chr11_+_32155483 2.98 ENSMUST00000121182.2
small nuclear ribonucleoprotein 25 (U11/U12)
chr13_-_56326695 2.97 ENSMUST00000225063.2
TRAF-interacting protein with forkhead-associated domain, family member B
chrX_-_149595873 2.97 ENSMUST00000131241.2
ENSMUST00000147152.3
ENSMUST00000143843.8
MAGE family member D2
chr6_-_68713748 2.97 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr7_-_24705320 2.96 ENSMUST00000102858.10
ENSMUST00000196684.2
ENSMUST00000080882.11
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr11_-_53371050 2.96 ENSMUST00000104955.4
sosondowah ankyrin repeat domain family member A
chr7_+_92469100 2.93 ENSMUST00000107180.8
ENSMUST00000107179.2
RAB30, member RAS oncogene family
chr14_-_70415117 2.90 ENSMUST00000022681.11
PDZ and LIM domain 2
chr4_+_130643260 2.88 ENSMUST00000030316.7
lysosomal-associated protein transmembrane 5
chr4_-_116228921 2.87 ENSMUST00000239239.2
ENSMUST00000239177.2
microtubule associated serine/threonine kinase 2
chr17_-_43813664 2.83 ENSMUST00000024707.9
ENSMUST00000117137.8
meprin 1 alpha
chr5_-_151574620 2.81 ENSMUST00000038131.10
replication factor C (activator 1) 3
chr8_+_36561982 2.81 ENSMUST00000110492.2
PEAK1 related kinase activating pseudokinase 1
chr7_-_80037153 2.78 ENSMUST00000206728.2
feline sarcoma oncogene
chr12_-_79054050 2.75 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chrX_-_36253309 2.73 ENSMUST00000060474.14
ENSMUST00000053456.11
ENSMUST00000115239.10
septin 6
chr7_-_44180700 2.71 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr13_-_56326511 2.71 ENSMUST00000169652.3
TRAF-interacting protein with forkhead-associated domain, family member B
chr4_-_131695135 2.71 ENSMUST00000146443.8
ENSMUST00000135579.8
erythrocyte membrane protein band 4.1
chr11_+_69856222 2.70 ENSMUST00000018713.13
claudin 7
chr1_+_135060994 2.68 ENSMUST00000167080.3
protein tyrosine phosphatase, non-receptor type 7
chr15_-_78657640 2.66 ENSMUST00000018313.6
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr11_-_100036792 2.66 ENSMUST00000007317.8
keratin 19
chr11_+_61847622 2.66 ENSMUST00000202389.4
sperm antigen with calponin homology and coiled-coil domains 1
chr8_+_72050292 2.65 ENSMUST00000143662.8
niban apoptosis regulator 3
chr11_-_107607343 2.62 ENSMUST00000021065.6
calcium channel, voltage-dependent, gamma subunit 1
chr5_+_21748523 2.60 ENSMUST00000035651.6
leucine rich repeat containing 17
chr2_-_122441719 2.60 ENSMUST00000028624.9
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr4_-_93223746 2.59 ENSMUST00000066774.6
tumor suppressor candidate 1
chr1_-_171061902 2.57 ENSMUST00000079957.12
Fc receptor, IgE, high affinity I, gamma polypeptide
chr12_+_112978051 2.57 ENSMUST00000223502.2
ENSMUST00000084891.5
ENSMUST00000220541.2
phosphofurin acidic cluster sorting protein 2
chr7_+_141996067 2.53 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr6_+_40941688 2.53 ENSMUST00000076638.7
RIKEN cDNA 1810009J06 gene
chr5_-_140612993 2.52 ENSMUST00000199157.2
tweety family member 3
chr4_+_132968082 2.51 ENSMUST00000030677.7
mitogen-activated protein kinase kinase kinase 6
chr16_+_87350202 2.50 ENSMUST00000026700.8
Map3k7 C-terminal like
chr16_+_49620883 2.45 ENSMUST00000229640.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr8_+_46338557 2.41 ENSMUST00000210422.2
PDZ and LIM domain 3
chr11_+_69806866 2.40 ENSMUST00000134581.2
G protein pathway suppressor 2
chr15_-_36598263 2.39 ENSMUST00000155116.2
poly(A) binding protein, cytoplasmic 1
chr12_+_26519203 2.38 ENSMUST00000020969.5
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_+_56610321 2.34 ENSMUST00000001258.15
ubiquitin-like, containing PHD and RING finger domains, 1
chrX_-_56384089 2.32 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr9_+_21249118 2.30 ENSMUST00000034697.8
solute carrier family 44, member 2
chr1_+_135764092 2.24 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr10_+_126899468 2.21 ENSMUST00000120226.8
ENSMUST00000133115.8
cyclin-dependent kinase 4
chr2_+_156681991 2.20 ENSMUST00000073352.10
TGFB-induced factor homeobox 2
chr19_+_56536685 2.18 ENSMUST00000071423.7
NHL repeat containing 2
chr9_-_39515420 2.18 ENSMUST00000042485.11
ENSMUST00000141370.8
expressed sequence AW551984
chr1_+_75336965 2.13 ENSMUST00000027409.10
desmin
chr2_-_125348305 2.08 ENSMUST00000028633.13
fibrillin 1
chr7_+_44866095 2.07 ENSMUST00000209437.2
TEA domain family member 2
chr7_-_105131407 2.06 ENSMUST00000047040.4
caveolae associated 3
chr17_+_56610396 2.03 ENSMUST00000113038.8
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_131664478 2.02 ENSMUST00000155990.8
erythrocyte membrane protein band 4.1
chr19_+_6326755 1.98 ENSMUST00000025684.4
EH-domain containing 1
chr5_-_73413888 1.96 ENSMUST00000101127.12
FRY like transcription coactivator
chr7_+_28488380 1.95 ENSMUST00000209035.2
ENSMUST00000059857.8
Ras and Rab interactor-like
chr11_+_63019799 1.94 ENSMUST00000108702.8
peripheral myelin protein 22
chr7_+_126811831 1.93 ENSMUST00000127710.3
myosin light chain, phosphorylatable, fast skeletal muscle
chr19_+_53128901 1.93 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)
chr4_-_137137088 1.92 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr9_+_107468146 1.90 ENSMUST00000195746.2
interferon-related developmental regulator 2
chr2_+_25152600 1.89 ENSMUST00000114336.4
taperin
chr13_-_111945499 1.88 ENSMUST00000109267.9
mitogen-activated protein kinase kinase kinase 1
chr10_-_128755127 1.86 ENSMUST00000149961.2
ENSMUST00000026406.14
retinol dehydrogenase 5
chr2_-_167503416 1.86 ENSMUST00000125544.3
ENSMUST00000006587.7
predicted gene 20431
transmembrane protein 189
chr5_+_35146727 1.85 ENSMUST00000114284.8
regulator of G-protein signaling 12
chr9_-_40257586 1.84 ENSMUST00000121357.8
GRAM domain containing 1B
chr5_-_137530214 1.81 ENSMUST00000140139.2
guanine nucleotide binding protein (G protein), beta 2
chr6_-_68609426 1.80 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr2_-_91854844 1.79 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chr11_+_96820091 1.78 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr11_+_3152874 1.75 ENSMUST00000179770.8
ENSMUST00000110048.8
eukaryotic translation initiation factor 4E nuclear import factor 1
chr15_-_82128538 1.73 ENSMUST00000229747.2
ENSMUST00000230408.2
centromere protein M
chr7_-_80037622 1.73 ENSMUST00000206698.2
feline sarcoma oncogene
chr7_-_126224848 1.72 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr12_-_114672701 1.71 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr17_+_75485791 1.70 ENSMUST00000135447.8
ENSMUST00000112516.8
latent transforming growth factor beta binding protein 1
chr17_+_35413415 1.70 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr8_+_106245368 1.69 ENSMUST00000034363.7
hydroxysteroid 11-beta dehydrogenase 2
chr15_-_82128888 1.67 ENSMUST00000089155.6
ENSMUST00000089157.11
centromere protein M
chr19_-_6065181 1.67 ENSMUST00000236537.2
ENSMUST00000025891.11
calpain 1
chr6_-_85351524 1.67 ENSMUST00000060837.10
RAB11 family interacting protein 5 (class I)
chr2_+_124910037 1.66 ENSMUST00000070353.4
solute carrier family 24, member 5
chr19_-_56536646 1.66 ENSMUST00000182276.2
DNA cross-link repair 1A
chr2_+_118943274 1.65 ENSMUST00000140939.8
ENSMUST00000028795.10
RAD51 recombinase
chr7_+_101060093 1.64 ENSMUST00000084894.15
predicted gene 45837
chr11_+_99748741 1.63 ENSMUST00000107434.2
predicted gene 11568
chr2_-_164621641 1.62 ENSMUST00000103095.5
troponin C2, fast
chr7_+_19144950 1.62 ENSMUST00000208710.2
ENSMUST00000003643.3
creatine kinase, muscle
chr1_-_182929025 1.61 ENSMUST00000171366.7
dispatched RND transporter family member 1
chr6_-_69792108 1.61 ENSMUST00000103367.3
immunoglobulin kappa variable 12-44
chr7_+_24982206 1.61 ENSMUST00000165239.3
capicua transcriptional repressor
chr5_+_35146880 1.59 ENSMUST00000114285.8
regulator of G-protein signaling 12
chr11_+_115705550 1.58 ENSMUST00000021134.10
ENSMUST00000106481.9
tRNA splicing endonuclease subunit 54
chr13_+_37529184 1.56 ENSMUST00000021860.7
lymphocyte antigen 86
chr7_+_3339077 1.56 ENSMUST00000203566.3
myeloid-associated differentiation marker
chr11_+_70548622 1.56 ENSMUST00000170716.8
enolase 3, beta muscle
chr19_+_32463151 1.55 ENSMUST00000025827.10
multiple inositol polyphosphate histidine phosphatase 1
chr5_-_114911548 1.55 ENSMUST00000178440.8
ENSMUST00000043283.14
ENSMUST00000112185.9
ENSMUST00000155908.8
GIT ArfGAP 2
chr7_+_3339059 1.55 ENSMUST00000096744.8
myeloid-associated differentiation marker
chr8_-_106198112 1.54 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr7_-_141579689 1.54 ENSMUST00000209732.2
MOB kinase activator 2
chr14_-_30329765 1.53 ENSMUST00000112207.8
ENSMUST00000112206.8
ENSMUST00000112202.8
ENSMUST00000112203.2
protein kinase C, delta
chrX_+_70600481 1.53 ENSMUST00000123100.2
high mobility group box 3
chr3_-_75177378 1.52 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr16_+_57173456 1.51 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr16_+_35590745 1.51 ENSMUST00000231579.2
Hspb associated protein 1
chr11_-_120538928 1.50 ENSMUST00000239158.2
ENSMUST00000026134.3
myeloid-associated differentiation marker-like 2
chr7_+_67602565 1.49 ENSMUST00000005671.10
insulin-like growth factor I receptor
chr2_-_92222979 1.49 ENSMUST00000111279.9
mitogen-activated protein kinase 8 interacting protein 1
chrX_+_168662592 1.47 ENSMUST00000112105.8
ENSMUST00000078947.12
midline 1
chr6_-_68812291 1.46 ENSMUST00000199143.5
ENSMUST00000103335.3
immunoglobulin kappa chain variable 12-89

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 16.8 GO:0007144 female meiosis I(GO:0007144)
1.3 4.0 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
1.3 5.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
1.2 3.7 GO:0034117 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
1.2 10.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.1 5.7 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
1.0 8.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.0 5.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.9 5.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.9 5.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.8 5.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.8 2.4 GO:0046072 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.8 3.8 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 6.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.8 3.0 GO:0021941 negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.7 11.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.7 0.7 GO:0072166 posterior mesonephric tubule development(GO:0072166)
0.7 17.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.7 3.4 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.6 1.8 GO:0006601 creatine biosynthetic process(GO:0006601)
0.6 7.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.6 4.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.6 2.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.6 1.7 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.6 2.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.6 1.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.6 1.7 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.5 9.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 1.6 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.5 2.1 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.5 2.1 GO:1901003 negative regulation of fermentation(GO:1901003)
0.5 3.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5 2.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.5 1.0 GO:0003032 detection of oxygen(GO:0003032)
0.5 2.9 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.5 1.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.5 1.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 7.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.5 13.0 GO:0015701 bicarbonate transport(GO:0015701)
0.5 7.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 1.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.5 1.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.4 4.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 1.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.4 1.3 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.4 10.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.4 1.7 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.4 18.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.4 64.2 GO:0007586 digestion(GO:0007586)
0.4 1.2 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.4 1.6 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.4 3.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.4 3.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.4 1.5 GO:0023021 termination of signal transduction(GO:0023021)
0.4 1.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 3.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.4 1.5 GO:1903944 estrous cycle(GO:0044849) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.4 3.0 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.4 3.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.4 1.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.4 2.2 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3 1.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 1.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 2.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.3 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.3 1.0 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
0.3 2.6 GO:0048539 bone marrow development(GO:0048539)
0.3 0.6 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 11.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.3 2.8 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 0.9 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.3 2.4 GO:0008228 opsonization(GO:0008228)
0.3 1.8 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.3 1.2 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.3 0.9 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.3 4.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.3 1.2 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.3 1.2 GO:0060988 lipid tube assembly(GO:0060988)
0.3 1.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 2.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 0.6 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.3 7.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.3 4.4 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.3 3.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.3 4.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 1.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 2.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 1.0 GO:0090096 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 2.2 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 9.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 1.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 3.3 GO:0060033 anatomical structure regression(GO:0060033)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 1.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.2 GO:0061743 motor learning(GO:0061743)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 1.3 GO:0010288 response to lead ion(GO:0010288)
0.2 1.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2 1.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.5 GO:0098749 cerebellar neuron development(GO:0098749)
0.2 0.8 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.2 1.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 6.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 1.3 GO:0031179 peptide modification(GO:0031179)
0.2 0.8 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.4 GO:0036371 T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.2 0.6 GO:0099542 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 2.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.0 GO:0006868 glutamine transport(GO:0006868)
0.1 1.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 5.3 GO:0030220 platelet formation(GO:0030220)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.0 GO:0032202 telomere assembly(GO:0032202)
0.1 2.1 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 1.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 2.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.7 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 2.8 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 0.9 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 2.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 1.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 2.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.5 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.3 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.3 GO:2000554 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.1 0.3 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 2.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 4.5 GO:0031116 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 1.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 2.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.3 GO:0086045 membrane depolarization during AV node cell action potential(GO:0086045)
0.1 0.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.4 GO:1902307 positive regulation of sodium ion transmembrane transport(GO:1902307)
0.1 1.0 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1 0.9 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.5 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 2.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 2.1 GO:0032060 bleb assembly(GO:0032060)
0.1 3.0 GO:0000154 rRNA modification(GO:0000154)
0.1 0.4 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.1 2.2 GO:0045109 intermediate filament organization(GO:0045109)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.5 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.5 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 2.0 GO:0048266 behavioral response to pain(GO:0048266)
0.1 2.3 GO:0030225 macrophage differentiation(GO:0030225)
0.1 1.6 GO:0006301 postreplication repair(GO:0006301)
0.1 0.5 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.7 GO:0060017 parathyroid gland development(GO:0060017)
0.1 2.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.3 GO:0061009 common bile duct development(GO:0061009)
0.1 0.2 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.0 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 2.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.3 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 2.4 GO:0031648 protein destabilization(GO:0031648)
0.0 3.3 GO:0065002 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.0 6.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 1.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.2 GO:0071549 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.5 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.5 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.6 GO:0080111 DNA demethylation(GO:0080111)
0.0 10.1 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 2.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.3 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 1.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.1 GO:0046785 microtubule polymerization(GO:0046785)
0.0 2.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 3.8 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.8 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 5.7 GO:0072659 protein localization to plasma membrane(GO:0072659)
0.0 0.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 2.4 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.5 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 3.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 5.1 GO:0008380 RNA splicing(GO:0008380)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
2.0 6.1 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
1.7 5.1 GO:0031904 endosome lumen(GO:0031904)
1.6 17.6 GO:0097451 glial limiting end-foot(GO:0097451)
1.2 18.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.0 12.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.0 3.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.9 2.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.8 3.3 GO:0014802 terminal cisterna(GO:0014802)
0.7 6.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.7 2.0 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.7 12.4 GO:0005861 troponin complex(GO:0005861)
0.6 17.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 7.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.5 1.5 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.5 1.5 GO:0043512 inhibin A complex(GO:0043512)
0.5 2.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.4 2.5 GO:0097149 centralspindlin complex(GO:0097149)
0.4 6.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 13.3 GO:0042588 zymogen granule(GO:0042588)
0.3 3.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 2.7 GO:1990357 terminal web(GO:1990357)
0.3 7.4 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 1.0 GO:0060171 stereocilium membrane(GO:0060171)
0.2 2.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.9 GO:0036284 tubulobulbar complex(GO:0036284)
0.2 1.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 1.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 4.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 6.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 2.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 10.0 GO:0031672 A band(GO:0031672)
0.2 2.1 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 2.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 3.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 11.8 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 12.2 GO:0014704 intercalated disc(GO:0014704)
0.1 1.3 GO:0061574 ASAP complex(GO:0061574)
0.1 18.9 GO:0000922 spindle pole(GO:0000922)
0.1 1.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 3.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 4.0 GO:0097440 apical dendrite(GO:0097440)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 5.7 GO:0000791 euchromatin(GO:0000791)
0.1 4.2 GO:0099738 cell cortex region(GO:0099738)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 2.5 GO:0005795 Golgi stack(GO:0005795)
0.1 6.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.1 3.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 9.3 GO:0005819 spindle(GO:0005819)
0.1 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.7 GO:0043218 compact myelin(GO:0043218)
0.1 6.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 6.7 GO:0016605 PML body(GO:0016605)
0.1 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 4.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 15.2 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.7 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0030904 retromer complex(GO:0030904)
0.0 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 53.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0036396 MIS complex(GO:0036396)
0.0 6.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 2.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.4 GO:0000776 kinetochore(GO:0000776)
0.0 2.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0050253 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
2.1 19.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.8 18.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.2 6.1 GO:0019767 IgE receptor activity(GO:0019767)
1.1 5.3 GO:0070051 fibrinogen binding(GO:0070051)
1.0 3.0 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.9 3.7 GO:0048030 disaccharide binding(GO:0048030)
0.9 27.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.9 2.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 8.6 GO:0031014 troponin T binding(GO:0031014)
0.8 2.4 GO:0004798 thymidylate kinase activity(GO:0004798)
0.6 4.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 6.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6 1.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.6 2.2 GO:0030172 troponin C binding(GO:0030172)
0.5 12.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.5 2.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.5 32.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 10.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 1.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.4 1.6 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.3 1.4 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.3 1.4 GO:0038100 nodal binding(GO:0038100)
0.3 1.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 3.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.3 1.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 2.8 GO:0000150 recombinase activity(GO:0000150)
0.3 1.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 1.8 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 76.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.3 2.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 1.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 20.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 1.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 2.2 GO:0051425 PTB domain binding(GO:0051425)
0.3 1.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.3 1.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.3 2.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 2.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 3.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.6 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 1.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 2.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 7.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 5.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 1.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.2 10.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.5 GO:0043559 insulin binding(GO:0043559)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.5 GO:0034711 inhibin binding(GO:0034711)
0.2 7.9 GO:0003785 actin monomer binding(GO:0003785)
0.2 5.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 6.0 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 2.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 1.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 2.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 6.0 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 4.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.2 GO:0043495 protein anchor(GO:0043495)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 8.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.6 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 14.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 11.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 3.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 2.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 5.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 4.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 6.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.1 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 3.3 GO:0003924 GTPase activity(GO:0003924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 16.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4 9.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 13.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 9.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 11.2 PID EPO PATHWAY EPO signaling pathway
0.2 4.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 16.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 6.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 9.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 7.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 19.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 5.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 5.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 0.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.3 PID AURORA B PATHWAY Aurora B signaling
0.0 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 16.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.8 24.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 39.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 6.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 17.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 8.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 11.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 4.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 10.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 9.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 4.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 3.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 1.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2 5.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 5.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.6 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 0.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 1.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 2.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 13.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.2 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 2.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 3.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.6 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins