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GSE58827: Dynamics of the Mouse Liver

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Results for Tcf7_Tcf7l2

Z-value: 0.72

Motif logo

Transcription factors associated with Tcf7_Tcf7l2

Gene Symbol Gene ID Gene Info
ENSMUSG00000000782.17 transcription factor 7, T cell specific
ENSMUSG00000024985.21 transcription factor 7 like 2, T cell specific, HMG box

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7mm39_v1_chr11_-_52174129_521742210.563.8e-04Click!
Tcf7l2mm39_v1_chr19_+_55886708_558867410.492.7e-03Click!

Activity profile of Tcf7_Tcf7l2 motif

Sorted Z-values of Tcf7_Tcf7l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_145816774 4.74 ENSMUST00000035918.8
cytochrome P450, family 3, subfamily a, polypeptide 11
chr2_+_102536701 3.93 ENSMUST00000123759.8
ENSMUST00000005220.11
ENSMUST00000111212.8
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_88093726 3.55 ENSMUST00000097659.5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr10_-_127206300 3.48 ENSMUST00000026472.10
inhibin beta-C
chr7_+_13467422 3.40 ENSMUST00000086148.8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr10_-_95678748 3.01 ENSMUST00000210336.2
predicted gene, 33543
chr3_+_118355778 2.95 ENSMUST00000039177.12
dihydropyrimidine dehydrogenase
chr10_-_95678786 2.93 ENSMUST00000211096.2
predicted gene, 33543
chr1_-_139487951 2.91 ENSMUST00000023965.8
complement factor H-related 1
chr7_+_13357892 2.43 ENSMUST00000108525.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr6_+_115398996 2.39 ENSMUST00000000450.5
peroxisome proliferator activated receptor gamma
chr1_-_139708906 2.33 ENSMUST00000111986.8
ENSMUST00000027612.11
ENSMUST00000111989.9
complement factor H-related 4
chr3_+_118355811 2.24 ENSMUST00000149101.3
dihydropyrimidine dehydrogenase
chr19_+_39980868 2.18 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr7_+_25760922 2.16 ENSMUST00000005669.9
cytochrome P450, family 2, subfamily b, polypeptide 13
chr2_-_154916367 2.14 ENSMUST00000137242.2
ENSMUST00000054607.16
S-adenosylhomocysteine hydrolase
chr4_+_45848918 1.96 ENSMUST00000030011.6
STRA6-like
chr6_-_47790272 1.94 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr9_+_46151994 1.88 ENSMUST00000034585.7
apolipoprotein A-IV
chr13_+_24511387 1.85 ENSMUST00000224953.2
ENSMUST00000050859.13
ENSMUST00000167746.8
ENSMUST00000224819.2
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr8_-_25066313 1.79 ENSMUST00000121992.2
indoleamine 2,3-dioxygenase 2
chr5_-_145406533 1.77 ENSMUST00000031633.5
cytochrome P450, family 3, subfamily a, polypeptide 16
chr16_+_22739028 1.73 ENSMUST00000232097.2
fetuin beta
chr8_-_112356957 1.63 ENSMUST00000070004.4
lactate dehydrogenase D
chr5_-_87716882 1.61 ENSMUST00000113314.3
sulfotransferase family 1D, member 1
chr19_+_58658779 1.61 ENSMUST00000057270.9
pancreatic lipase
chr10_-_115423644 1.60 ENSMUST00000020350.15
leucine rich repeat containing G protein coupled receptor 5
chr8_-_112417633 1.58 ENSMUST00000034435.7
chymotrypsinogen B1
chrX_+_59044796 1.57 ENSMUST00000033477.5
coagulation factor IX
chr7_+_67305162 1.55 ENSMUST00000107470.2
tetratricopeptide repeat domain 23
chr14_-_34077340 1.50 ENSMUST00000052126.6
family with sequence similarity 25, member C
chr11_-_52174129 1.42 ENSMUST00000109071.3
transcription factor 7, T cell specific
chr15_-_54141816 1.42 ENSMUST00000079772.4
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr13_-_56696310 1.40 ENSMUST00000062806.6
leukocyte cell-derived chemotaxin 2
chr9_+_77829191 1.39 ENSMUST00000133757.8
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr13_-_56696222 1.38 ENSMUST00000225183.2
leukocyte cell-derived chemotaxin 2
chr19_+_58658838 1.37 ENSMUST00000238108.2
pancreatic lipase
chr19_+_44980565 1.37 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_+_117145496 1.35 ENSMUST00000112866.8
ENSMUST00000112871.8
ENSMUST00000073043.5
chemokine (C-X-C motif) ligand 12
chr7_-_30776081 1.33 ENSMUST00000072331.13
ENSMUST00000167369.8
FXYD domain-containing ion transport regulator 3
chr2_-_34990689 1.30 ENSMUST00000226631.2
ENSMUST00000045776.5
ENSMUST00000226972.2
expressed sequence AI182371
chr1_+_87998487 1.25 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr19_+_4771089 1.21 ENSMUST00000238976.3
spectrin beta, non-erythrocytic 2
chr3_-_113166153 1.15 ENSMUST00000098673.5
amylase 2a5
chr2_+_22958179 1.14 ENSMUST00000227663.2
ENSMUST00000028121.15
ENSMUST00000227809.2
ENSMUST00000144088.2
acyl-Coenzyme A binding domain containing 5
chr12_-_84455764 1.12 ENSMUST00000120942.8
ENSMUST00000110272.9
ectonucleoside triphosphate diphosphohydrolase 5
chr1_+_128171859 1.10 ENSMUST00000027592.6
UBX domain protein 4
chr1_+_157334298 1.09 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr1_+_157334347 1.08 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr10_+_75242745 1.07 ENSMUST00000039925.8
ureidopropionase, beta
chr15_+_10981833 1.06 ENSMUST00000070877.7
alpha-methylacyl-CoA racemase
chr17_+_79922329 1.05 ENSMUST00000040368.3
regulator of microtubule dynamics 2
chr13_-_41981812 1.05 ENSMUST00000223337.2
ENSMUST00000221691.2
androgen dependent TFPI regulating protein
chr7_+_132460954 1.05 ENSMUST00000084497.12
ENSMUST00000106161.8
BRISC complex subunit
chr17_-_35077089 1.03 ENSMUST00000153400.8
complement factor B
chr13_-_41981893 1.03 ENSMUST00000137905.2
androgen dependent TFPI regulating protein
chr17_+_79922486 1.03 ENSMUST00000225357.2
regulator of microtubule dynamics 2
chr18_+_84106188 1.01 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr10_-_24803336 1.00 ENSMUST00000020161.10
arginase, liver
chr14_-_70561231 0.99 ENSMUST00000151011.8
solute carrier family 39 (zinc transporter), member 14
chr6_+_54244116 0.97 ENSMUST00000114402.9
chimerin 2
chr10_+_89580849 0.96 ENSMUST00000020112.7
UHRF1 (ICBP90) binding protein 1-like
chr9_-_15212745 0.96 ENSMUST00000217042.2
RIKEN cDNA 4931406C07 gene
chr12_+_87193922 0.95 ENSMUST00000222885.2
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr13_+_24054267 0.95 ENSMUST00000006785.8
solute carrier family 17 (sodium phosphate), member 1
chr7_-_144493560 0.93 ENSMUST00000093962.5
cyclin D1
chr2_-_34951443 0.92 ENSMUST00000028233.7
hemolytic complement
chr10_+_61484331 0.91 ENSMUST00000020286.7
pyrophosphatase (inorganic) 1
chr9_-_15212849 0.89 ENSMUST00000034414.10
RIKEN cDNA 4931406C07 gene
chr6_+_138117295 0.88 ENSMUST00000008684.11
microsomal glutathione S-transferase 1
chr6_+_138117519 0.87 ENSMUST00000120939.8
ENSMUST00000204628.3
ENSMUST00000140932.2
ENSMUST00000120302.8
microsomal glutathione S-transferase 1
chr6_+_54016543 0.87 ENSMUST00000046856.14
chimerin 2
chr14_-_45456821 0.86 ENSMUST00000128484.8
ENSMUST00000147853.8
ENSMUST00000022377.11
ENSMUST00000143609.2
ENSMUST00000153383.8
ENSMUST00000139526.9
thioredoxin domain containing 16
chr3_+_57332735 0.85 ENSMUST00000029377.8
transmembrane 4 superfamily member 4
chr1_+_87983189 0.85 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr3_+_122277372 0.84 ENSMUST00000197073.2
breast cancer anti-estrogen resistance 3
chr11_-_59927688 0.84 ENSMUST00000102692.10
phosphatidylethanolamine N-methyltransferase
chr2_+_14234198 0.82 ENSMUST00000028045.4
mannose receptor, C type 1
chr15_+_31224460 0.81 ENSMUST00000044524.16
death-associated protein
chr8_+_36924702 0.81 ENSMUST00000135373.8
ENSMUST00000147525.9
tRNA methyltransferase 9B
chr7_-_34914675 0.81 ENSMUST00000118444.3
ENSMUST00000122409.8
low density lipoprotein receptor-related protein 3
chr4_-_19922599 0.79 ENSMUST00000029900.6
ATPase, H+ transporting, lysosomal V0 subunit D2
chr3_-_53771185 0.79 ENSMUST00000122330.2
ENSMUST00000146598.8
ubiquitin-fold modifier 1
chr1_+_87983099 0.79 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr13_+_47276132 0.78 ENSMUST00000068891.12
ring finger protein 144B
chr9_+_106325828 0.78 ENSMUST00000217496.2
abhydrolase domain containing 14b
chr11_+_108811626 0.78 ENSMUST00000140821.2
axin 2
chr9_-_122694999 0.75 ENSMUST00000214558.2
ENSMUST00000216721.2
zinc finger protein 445
chr7_-_101494472 0.74 ENSMUST00000211566.2
ENSMUST00000094141.7
ENSMUST00000209329.2
folate receptor 2 (fetal)
chr9_-_96634874 0.72 ENSMUST00000152594.8
zinc finger and BTB domain containing 38
chr2_+_70305267 0.72 ENSMUST00000100043.3
trans-acting transcription factor 5
chr9_-_96601574 0.71 ENSMUST00000128269.8
zinc finger and BTB domain containing 38
chr2_+_22958956 0.71 ENSMUST00000226571.2
ENSMUST00000114529.10
ENSMUST00000114526.9
ENSMUST00000228050.2
acyl-Coenzyme A binding domain containing 5
chr4_-_63072367 0.69 ENSMUST00000030041.5
alpha 1 microglobulin/bikunin precursor
chr5_+_138083345 0.69 ENSMUST00000019660.11
ENSMUST00000066617.12
ENSMUST00000110963.8
zinc finger with KRAB and SCAN domains 1
chr6_+_21985902 0.69 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr9_+_106325860 0.69 ENSMUST00000185527.3
abhydrolase domain containing 14b
chr8_+_96078886 0.67 ENSMUST00000034243.7
matrix metallopeptidase 15
chr2_+_20742115 0.67 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr14_-_61283911 0.65 ENSMUST00000111234.10
ENSMUST00000224371.2
tumor necrosis factor receptor superfamily, member 19
chr14_-_45626237 0.65 ENSMUST00000227865.2
ENSMUST00000226856.2
ENSMUST00000226276.2
ENSMUST00000046191.9
glucosamine-phosphate N-acetyltransferase 1
chr11_+_98938137 0.64 ENSMUST00000140772.2
insulin-like growth factor binding protein 4
chr5_+_91039092 0.64 ENSMUST00000031327.9
chemokine (C-X-C motif) ligand 1
chr4_+_148686985 0.62 ENSMUST00000105701.9
ENSMUST00000052060.7
mannan-binding lectin serine peptidase 2
chr5_-_105387395 0.61 ENSMUST00000065588.7
guanylate-binding protein 10
chr3_+_122305819 0.61 ENSMUST00000199344.2
breast cancer anti-estrogen resistance 3
chr11_-_99213769 0.61 ENSMUST00000038004.3
keratin 25
chr4_+_134124691 0.60 ENSMUST00000105870.8
platelet-activating factor acetylhydrolase 2
chr11_+_108271990 0.59 ENSMUST00000146050.2
ENSMUST00000152958.8
apolipoprotein H
chr1_-_59276252 0.58 ENSMUST00000163058.2
ENSMUST00000160945.2
ENSMUST00000027178.13
alsin Rho guanine nucleotide exchange factor
chr6_+_78382131 0.58 ENSMUST00000023906.4
regenerating islet-derived 2
chr1_+_182782335 0.57 ENSMUST00000193687.7
toll-like receptor 5
chr6_-_148732893 0.56 ENSMUST00000145960.2
importin 8
chr10_+_127685785 0.55 ENSMUST00000077530.3
retinol dehydrogenase 19
chr7_+_37883300 0.55 ENSMUST00000179992.10
RIKEN cDNA 1600014C10 gene
chr7_+_37883216 0.55 ENSMUST00000177983.2
RIKEN cDNA 1600014C10 gene
chr11_+_114743044 0.55 ENSMUST00000142262.2
G protein-coupled receptor, family C, group 5, member C
chr14_+_26959975 0.54 ENSMUST00000049206.6
Rho guanine nucleotide exchange factor (GEF) 3
chr9_-_50657800 0.54 ENSMUST00000239417.2
ENSMUST00000034564.4
RIKEN cDNA 2310030G06 gene
chr10_-_94780695 0.54 ENSMUST00000099337.5
plexin C1
chr10_-_128425519 0.54 ENSMUST00000082059.7
erb-b2 receptor tyrosine kinase 3
chr2_+_91033230 0.54 ENSMUST00000150403.8
ENSMUST00000002172.14
ENSMUST00000238832.2
ENSMUST00000239169.2
ENSMUST00000155418.2
acid phosphatase 2, lysosomal
chr4_-_124744266 0.54 ENSMUST00000137769.3
RIKEN cDNA 1110065P20 gene
chr9_-_86577940 0.54 ENSMUST00000034989.15
malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_+_102036356 0.53 ENSMUST00000055409.6
N-acetylglutamate synthase
chr9_-_122695071 0.53 ENSMUST00000216063.2
zinc finger protein 445
chr7_-_79492091 0.52 ENSMUST00000049004.8
alanyl (membrane) aminopeptidase
chr19_+_8816663 0.52 ENSMUST00000160556.8
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_65288418 0.52 ENSMUST00000101191.10
ENSMUST00000204348.3
kelch-like 5
chr13_+_33187205 0.52 ENSMUST00000063191.14
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr4_+_141095415 0.52 ENSMUST00000006380.5
family with sequence similarity 131, member C
chr4_+_40723083 0.52 ENSMUST00000149794.2
DnaJ heat shock protein family (Hsp40) member A1
chr6_-_148732946 0.52 ENSMUST00000048418.14
importin 8
chr13_-_104056803 0.51 ENSMUST00000091269.11
ENSMUST00000188997.7
ENSMUST00000169083.8
ENSMUST00000191275.7
Erbb2 interacting protein
chr3_+_137377285 0.51 ENSMUST00000166899.3
predicted gene, 21962
chr18_+_61688378 0.50 ENSMUST00000165721.8
ENSMUST00000115246.9
ENSMUST00000166990.8
ENSMUST00000163205.8
ENSMUST00000170862.8
casein kinase 1, alpha 1
chr5_+_143220897 0.50 ENSMUST00000077485.11
ENSMUST00000032591.15
zinc finger protein 12
chr2_+_30156733 0.50 ENSMUST00000113645.8
ENSMUST00000133877.8
ENSMUST00000139719.8
ENSMUST00000113643.8
ENSMUST00000150695.8
phytanoyl-CoA dioxygenase domain containing 1
chr14_+_56255422 0.50 ENSMUST00000022836.6
mast cell protease 1
chr1_+_88154727 0.50 ENSMUST00000061013.13
ENSMUST00000113130.8
maestro heat-like repeat family member 2A
chr19_+_38121248 0.49 ENSMUST00000025956.13
phosphodiesterase 6C, cGMP specific, cone, alpha prime
chr10_-_128204545 0.49 ENSMUST00000220027.2
coenzyme Q10A
chr5_+_118114795 0.49 ENSMUST00000202447.4
F-box protein 21
chr9_-_65734826 0.49 ENSMUST00000159109.2
zinc finger protein 609
chr3_+_85946145 0.48 ENSMUST00000238331.2
SH3 domain protein D19
chr12_-_79219382 0.48 ENSMUST00000055262.13
vesicle transport through interaction with t-SNAREs 1B
chr5_-_97259302 0.48 ENSMUST00000196078.5
progestin and adipoQ receptor family member III
chr13_+_24560052 0.48 ENSMUST00000110391.4
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr17_-_74257164 0.48 ENSMUST00000024866.6
xanthine dehydrogenase
chr10_-_128204806 0.48 ENSMUST00000043211.7
ENSMUST00000220227.2
coenzyme Q10A
chr13_+_54738014 0.47 ENSMUST00000026986.7
HIG1 domain family, member 2A
chr1_+_157286124 0.47 ENSMUST00000193791.6
ENSMUST00000046743.11
ENSMUST00000119891.7
crystallin zeta like 2
chr5_+_118114826 0.47 ENSMUST00000035579.10
F-box protein 21
chr5_-_147013384 0.47 ENSMUST00000016664.8
ligand of numb-protein X 2
chr14_+_12016304 0.47 ENSMUST00000161302.8
fragile histidine triad gene
chr6_+_34722926 0.47 ENSMUST00000126181.8
caldesmon 1
chr10_-_22696025 0.46 ENSMUST00000218002.2
ENSMUST00000049930.9
transcription factor 21
chr14_+_54669054 0.45 ENSMUST00000089688.6
ENSMUST00000225641.2
matrix metallopeptidase 14 (membrane-inserted)
chr19_+_38121214 0.45 ENSMUST00000112329.3
phosphodiesterase 6C, cGMP specific, cone, alpha prime
chr6_-_124718316 0.45 ENSMUST00000004389.6
gene rich cluster, C10 gene
chr2_+_134627987 0.45 ENSMUST00000131552.5
ENSMUST00000110116.8
phospholipase C, beta 1
chr15_+_9436114 0.45 ENSMUST00000042360.5
ENSMUST00000226688.2
calcyphosine-like
chr18_-_66155651 0.45 ENSMUST00000143990.2
lectin, mannose-binding, 1
chr2_+_71884943 0.44 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chr16_-_43959993 0.44 ENSMUST00000137557.8
ATPase, H+ transporting, lysosomal V1 subunit A
chr6_+_21986445 0.44 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr18_-_12996348 0.44 ENSMUST00000143077.8
ENSMUST00000117361.8
ENSMUST00000234871.2
oxysterol binding protein-like 1A
chr2_+_30156523 0.44 ENSMUST00000091132.13
phytanoyl-CoA dioxygenase domain containing 1
chr10_+_71183571 0.43 ENSMUST00000079252.13
inositol polyphosphate multikinase
chr10_+_38841511 0.43 ENSMUST00000019992.6
laminin, alpha 4
chr7_+_24310738 0.43 ENSMUST00000073325.6
pleckstrin homology like domain, family B, member 3
chr17_+_44263890 0.42 ENSMUST00000177857.9
ENSMUST00000044792.6
regulator of calcineurin 2
chr9_-_64248426 0.42 ENSMUST00000120760.8
ENSMUST00000168844.9
DIS3 like exosome 3'-5' exoribonuclease
chr4_+_99082373 0.41 ENSMUST00000180278.2
autophagy related 4C, cysteine peptidase
chr7_-_13723513 0.41 ENSMUST00000165167.8
ENSMUST00000108520.4
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr11_+_99755302 0.41 ENSMUST00000092694.4
predicted gene 11559
chr6_+_34722887 0.40 ENSMUST00000123823.8
ENSMUST00000136907.8
caldesmon 1
chr10_-_8761777 0.39 ENSMUST00000015449.6
SAM and SH3 domain containing 1
chr14_+_102078038 0.39 ENSMUST00000159314.8
LIM domain only 7
chr4_+_95855442 0.39 ENSMUST00000030306.14
hook microtubule tethering protein 1
chr10_-_122912272 0.39 ENSMUST00000219203.2
ENSMUST00000073792.11
MON2 homolog, regulator of endosome to Golgi trafficking
chr10_+_21854540 0.38 ENSMUST00000142174.8
ENSMUST00000164659.8
serum/glucocorticoid regulated kinase 1
chr3_-_59038031 0.38 ENSMUST00000091112.6
ENSMUST00000065220.13
purinergic receptor P2Y, G-protein coupled, 14
chr10_+_96453408 0.38 ENSMUST00000218953.2
BTG anti-proliferation factor 1
chr18_+_77031788 0.38 ENSMUST00000097522.11
ENSMUST00000097521.12
ENSMUST00000145634.9
haloacid dehalogenase-like hydrolase domain containing 2
chr1_-_171910324 0.37 ENSMUST00000003550.11
nicastrin
chr8_+_45960931 0.37 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr3_-_96721829 0.37 ENSMUST00000047702.8
CD160 antigen
chr14_+_63673843 0.37 ENSMUST00000121288.2
family with sequence similarity 167, member A
chr6_-_85684840 0.37 ENSMUST00000179613.2
N-acetyltransferase 8 (GCN5-related) family member 7
chr10_-_60983438 0.36 ENSMUST00000092498.12
ENSMUST00000137833.2
ENSMUST00000155919.8
sphingosine phosphate lyase 1
chr2_-_38816229 0.36 ENSMUST00000076275.11
ENSMUST00000142130.2
nuclear receptor subfamily 6, group A, member 1
chr2_+_163348728 0.36 ENSMUST00000143911.8
hepatic nuclear factor 4, alpha
chr14_+_52122439 0.35 ENSMUST00000167984.2
methyltransferase like 17
chr10_+_29189159 0.34 ENSMUST00000160399.8
enoyl Coenzyme A hydratase domain containing 1
chr5_-_44259374 0.34 ENSMUST00000171543.8
prominin 1
chr19_+_56276343 0.33 ENSMUST00000095948.11
hyaluronic acid binding protein 2
chr5_-_44259293 0.33 ENSMUST00000074113.13
prominin 1
chr13_-_108026590 0.33 ENSMUST00000225822.4
ENSMUST00000225197.3
zinc finger SWIM-type containing 6
chr10_-_30494431 0.33 ENSMUST00000161074.8
histidine triad nucleotide binding protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7_Tcf7l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0019860 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.7 3.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.7 2.0 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.6 1.9 GO:1903334 positive regulation of protein folding(GO:1903334)
0.6 2.4 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.6 2.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.6 3.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5 6.4 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5 2.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.4 1.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 2.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 1.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.6 GO:0000103 sulfate assimilation(GO:0000103)
0.2 2.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 0.6 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.2 1.2 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 1.0 GO:0090467 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.2 3.6 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.2 0.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.8 GO:0030242 pexophagy(GO:0030242)
0.2 1.8 GO:0006569 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.2 0.8 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.5 GO:0060435 bronchiole development(GO:0060435)
0.1 0.4 GO:0060466 interleukin-12-mediated signaling pathway(GO:0035722) activation of meiosis involved in egg activation(GO:0060466) cellular response to interleukin-12(GO:0071349) response to fluoride(GO:1902617)
0.1 1.4 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 1.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.7 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 4.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 0.8 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.4 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.1 1.1 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 1.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 1.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 1.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.2 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.2 GO:0042197 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.1 0.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.2 GO:2000331 positive regulation of Wnt protein secretion(GO:0061357) regulation of terminal button organization(GO:2000331)
0.1 1.1 GO:0046549 retinal cone cell development(GO:0046549)
0.1 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.5 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.3 GO:0060983 epicardium-derived cardiac endothelial cell differentiation(GO:0003349) epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.1 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.5 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.5 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.1 0.2 GO:0050822 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 3.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 1.1 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.7 GO:0015884 folic acid transport(GO:0015884)
0.0 1.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.5 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 1.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.1 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.7 GO:0001967 suckling behavior(GO:0001967)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.1 GO:1904156 DN2 thymocyte differentiation(GO:1904155) DN3 thymocyte differentiation(GO:1904156)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 1.6 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 1.4 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.0 0.5 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 2.3 GO:0031638 zymogen activation(GO:0031638)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 2.6 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.5 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.6 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0098967 synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0097447 dendritic tree(GO:0097447)
0.2 1.2 GO:0008091 spectrin(GO:0008091)
0.1 2.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 2.5 GO:0042627 chylomicron(GO:0042627)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.1 GO:0070552 BRISC complex(GO:0070552)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0071914 prominosome(GO:0071914)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 3.7 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 6.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 6.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
0.8 2.3 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.8 6.2 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.7 3.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.6 1.8 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.5 1.6 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.5 1.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.4 2.8 GO:0050656 alcohol sulfotransferase activity(GO:0004027) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 1.0 GO:0016034 maleylacetoacetate isomerase activity(GO:0016034)
0.3 2.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 1.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 1.9 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.9 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.5 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 0.7 GO:0019862 IgA binding(GO:0019862)
0.2 0.5 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 2.4 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.5 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 1.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 3.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 6.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.4 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 1.0 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.5 GO:0005118 sevenless binding(GO:0005118)
0.1 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0070540 stearic acid binding(GO:0070540)
0.1 0.5 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 4.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.5 GO:0034618 arginine binding(GO:0034618)
0.1 0.5 GO:0043546 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.1 1.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.2 GO:0001761 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.1 0.2 GO:0016824 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.6 GO:0005537 mannose binding(GO:0005537)
0.1 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.8 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 3.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.2 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.1 3.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.2 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 1.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 1.0 GO:0030553 cGMP binding(GO:0030553)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 5.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.7 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 2.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 6.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.2 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 1.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 3.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 3.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.0 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP