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GSE58827: Dynamics of the Mouse Liver

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Results for Tfap2d

Z-value: 1.19

Motif logo

Transcription factors associated with Tfap2d

Gene Symbol Gene ID Gene Info
ENSMUSG00000042596.8 transcription factor AP-2, delta

Activity profile of Tfap2d motif

Sorted Z-values of Tfap2d motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_57143437 6.67 ENSMUST00000095076.10
ENSMUST00000030142.4
erythrocyte membrane protein band 4.1 like 4b
chr10_-_88339935 6.59 ENSMUST00000117440.8
choline phosphotransferase 1
chrX_+_93278588 5.68 ENSMUST00000096369.10
ENSMUST00000113911.9
kelch-like 15
chrX_+_93278526 5.36 ENSMUST00000113908.8
ENSMUST00000113916.10
kelch-like 15
chr15_-_31367668 5.06 ENSMUST00000110410.10
ENSMUST00000076942.5
ankyrin repeat domain 33B
chr10_-_88339773 4.95 ENSMUST00000117579.8
ENSMUST00000073783.6
choline phosphotransferase 1
chr2_-_173117936 4.92 ENSMUST00000139306.2
prostate transmembrane protein, androgen induced 1
chr10_-_88339814 4.75 ENSMUST00000020253.15
choline phosphotransferase 1
chr2_+_167530835 4.28 ENSMUST00000070642.4
CCAAT/enhancer binding protein (C/EBP), beta
chr2_+_27567213 4.27 ENSMUST00000077257.12
retinoid X receptor alpha
chrX_+_93278203 4.13 ENSMUST00000153900.8
kelch-like 15
chr8_+_86219191 4.08 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr7_+_65511777 3.91 ENSMUST00000055576.12
ENSMUST00000098391.11
proprotein convertase subtilisin/kexin type 6
chr5_-_34345014 3.86 ENSMUST00000042701.13
ENSMUST00000119171.2
Max dimerization protein 4
chr7_-_34914675 3.59 ENSMUST00000118444.3
ENSMUST00000122409.8
low density lipoprotein receptor-related protein 3
chr17_+_37253802 3.50 ENSMUST00000040498.12
ring finger protein 39
chr4_-_46991842 3.45 ENSMUST00000107749.4
gamma-aminobutyric acid (GABA) B receptor, 2
chr10_+_61531282 3.29 ENSMUST00000020284.5
trypsin domain containing 1
chr12_-_30423356 3.27 ENSMUST00000021004.14
syntrophin, gamma 2
chr4_-_41640321 3.20 ENSMUST00000127306.2
energy homeostasis associated
chr15_-_31367872 3.07 ENSMUST00000123325.9
ankyrin repeat domain 33B
chr17_-_24428351 2.95 ENSMUST00000024931.6
netrin 3
chr2_+_155907658 2.84 ENSMUST00000137966.2
sperm associated antigen 4
chr7_+_65511482 2.78 ENSMUST00000176199.8
proprotein convertase subtilisin/kexin type 6
chr1_-_39616445 2.75 ENSMUST00000062525.11
ring finger protein 149
chr2_-_26096547 2.73 ENSMUST00000028302.8
LIM homeobox protein 3
chr8_-_121361097 2.69 ENSMUST00000123927.9
RIKEN cDNA 1190005I06 gene
chr4_-_108637700 2.68 ENSMUST00000106658.8
zinc finger, FYVE domain containing 9
chr13_+_119565424 2.60 ENSMUST00000026520.14
polyadenylate binding protein-interacting protein 1
chr6_-_124391994 2.57 ENSMUST00000035861.6
ENSMUST00000112532.8
ENSMUST00000080557.12
peroxisomal biogenesis factor 5
chr11_-_72686853 2.52 ENSMUST00000156294.8
cytochrome b5 domain containing 2
chr2_-_173118315 2.51 ENSMUST00000036248.13
prostate transmembrane protein, androgen induced 1
chr4_+_141095415 2.49 ENSMUST00000006380.5
family with sequence similarity 131, member C
chr6_+_72332423 2.49 ENSMUST00000069695.9
ENSMUST00000132243.3
transmembrane protein 150A
chr6_-_48422447 2.40 ENSMUST00000114564.8
zinc finger protein 467
chr4_+_40722911 2.32 ENSMUST00000164233.8
ENSMUST00000137246.8
ENSMUST00000125442.8
DnaJ heat shock protein family (Hsp40) member A1
chr8_+_36924702 2.31 ENSMUST00000135373.8
ENSMUST00000147525.9
tRNA methyltransferase 9B
chr6_+_72332449 2.25 ENSMUST00000206064.2
transmembrane protein 150A
chr2_+_27567246 2.24 ENSMUST00000166775.8
retinoid X receptor alpha
chr5_+_34445944 2.20 ENSMUST00000207754.2
cilia and flagella associated protein 99
chr14_+_73790105 2.20 ENSMUST00000160507.8
ENSMUST00000022706.7
succinate-Coenzyme A ligase, ADP-forming, beta subunit
chr4_+_84802650 2.16 ENSMUST00000169371.9
centlein, centrosomal protein
chr16_-_4238280 2.12 ENSMUST00000120080.8
adenylate cyclase 9
chr14_-_20844074 2.11 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr15_+_87428483 2.09 ENSMUST00000230414.2
TAFA chemokine like family member 5
chr5_+_119808722 2.09 ENSMUST00000079719.11
T-box 3
chr5_+_108842294 2.06 ENSMUST00000013633.12
fibroblast growth factor receptor-like 1
chr11_-_72686627 2.05 ENSMUST00000079681.6
cytochrome b5 domain containing 2
chr5_+_114706077 2.02 ENSMUST00000043650.8
family with sequence similarity 222, member A
chr4_-_108637979 2.02 ENSMUST00000106657.8
zinc finger, FYVE domain containing 9
chr5_+_119808890 2.02 ENSMUST00000121021.8
T-box 3
chr1_-_39616369 2.01 ENSMUST00000195705.2
ring finger protein 149
chr14_-_18817743 2.01 ENSMUST00000167430.8
predicted gene 3020
chr5_-_34445662 2.00 ENSMUST00000094868.10
zinc finger, FYVE domain containing 28
chr4_-_115875055 1.97 ENSMUST00000049095.6
fatty acid amide hydrolase
chr3_+_40904253 1.95 ENSMUST00000048490.13
La ribonucleoprotein domain family, member 1B
chr2_-_32872032 1.94 ENSMUST00000195863.2
ENSMUST00000028129.13
solute carrier family 2, (facilitated glucose transporter), member 8
chr4_+_84802592 1.90 ENSMUST00000102819.10
centlein, centrosomal protein
chr2_+_167922924 1.88 ENSMUST00000052125.7
par-6 family cell polarity regulator beta
chr17_-_66826661 1.88 ENSMUST00000167962.2
ENSMUST00000070538.12
RAB12, member RAS oncogene family
chr14_-_19420488 1.86 ENSMUST00000166494.2
predicted gene 2897
chr8_+_84699580 1.84 ENSMUST00000005606.8
protein kinase, cAMP dependent, catalytic, alpha
chr2_-_168072493 1.82 ENSMUST00000109193.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr14_+_14901127 1.81 ENSMUST00000163790.2
predicted gene 3558
chr12_+_103498542 1.79 ENSMUST00000021631.12
protein phosphatase 4, regulatory subunit 4
chr14_+_16508028 1.79 ENSMUST00000163885.2
predicted gene 3248
chr2_-_35091076 1.77 ENSMUST00000028238.15
RAB14, member RAS oncogene family
chr11_+_97690391 1.73 ENSMUST00000043843.12
LIM and SH3 protein 1
chr2_+_90677499 1.72 ENSMUST00000136872.8
ENSMUST00000150232.8
ENSMUST00000111467.4
mitochondrial carrier 2
chr11_+_108811626 1.72 ENSMUST00000140821.2
axin 2
chr14_+_16589391 1.71 ENSMUST00000164484.8
predicted gene 8237
chr2_-_32872019 1.68 ENSMUST00000153484.7
solute carrier family 2, (facilitated glucose transporter), member 8
chr7_-_79882501 1.68 ENSMUST00000065163.15
calcium and integrin binding 1 (calmyrin)
chr5_+_34817704 1.66 ENSMUST00000074651.11
ENSMUST00000001112.14
G protein-coupled receptor kinase 4
chr6_+_91661034 1.65 ENSMUST00000032185.9
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr8_-_70355208 1.64 ENSMUST00000110167.5
NADH:ubiquinone oxidoreductase subunit A13
chr4_+_84802513 1.63 ENSMUST00000047023.13
centlein, centrosomal protein
chr14_-_19635203 1.63 ENSMUST00000170694.9
predicted gene 2237
chr14_-_31552608 1.63 ENSMUST00000014640.9
ankyrin repeat domain 28
chr2_+_76505619 1.62 ENSMUST00000111920.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr5_+_88712840 1.59 ENSMUST00000196894.5
ENSMUST00000198965.5
RUN and FYVE domain containing 3
chr14_-_19261196 1.59 ENSMUST00000112797.12
ENSMUST00000225885.2
RIKEN cDNA D830030K20 gene
chr16_-_18405709 1.59 ENSMUST00000232335.2
T-box 1
chr11_-_107685383 1.59 ENSMUST00000021066.4
calcium channel, voltage-dependent, gamma subunit 4
chr7_-_127307898 1.57 ENSMUST00000207019.2
B cell CLL/lymphoma 7C
chr7_+_106969919 1.57 ENSMUST00000137663.2
synaptotagmin IX
chr9_-_29323500 1.56 ENSMUST00000115237.8
neurotrimin
chr7_+_106969950 1.56 ENSMUST00000073459.12
synaptotagmin IX
chr19_-_7183596 1.55 ENSMUST00000123594.8
OTU domain, ubiquitin aldehyde binding 1
chr2_+_92430043 1.55 ENSMUST00000065797.7
carbohydrate sulfotransferase 1
chr19_-_37340010 1.54 ENSMUST00000131070.3
insulin degrading enzyme
chr10_-_31485180 1.53 ENSMUST00000081989.8
ring finger protein 217
chr13_+_9326513 1.53 ENSMUST00000174552.8
disco interacting protein 2 homolog C
chr11_+_97690585 1.53 ENSMUST00000129558.8
LIM and SH3 protein 1
chr2_+_179666744 1.51 ENSMUST00000055485.12
LSM family member 14B
chr9_-_29323032 1.51 ENSMUST00000115236.2
neurotrimin
chr19_-_10582672 1.49 ENSMUST00000236478.2
ENSMUST00000236950.2
triokinase, FMN cyclase
chr2_-_35090961 1.46 ENSMUST00000230751.2
RAB14, member RAS oncogene family
chr5_+_28370687 1.46 ENSMUST00000036177.9
engrailed 2
chr2_+_30061469 1.46 ENSMUST00000015481.6
endonuclease G
chr19_-_4748696 1.45 ENSMUST00000225896.2
ENSMUST00000177696.8
predicted gene 960
chr16_-_35589726 1.44 ENSMUST00000023554.9
solute carrier family 49 member 4
chr19_-_7183626 1.43 ENSMUST00000025679.11
OTU domain, ubiquitin aldehyde binding 1
chr17_-_13271183 1.43 ENSMUST00000091648.4
G protein-coupled receptor 31, D17Leh66b region
chr14_-_31552335 1.43 ENSMUST00000228037.2
ankyrin repeat domain 28
chr7_-_141055044 1.43 ENSMUST00000043870.9
polymerase (RNA) II (DNA directed) polypeptide L
chr2_+_155907100 1.42 ENSMUST00000038860.12
sperm associated antigen 4
chr11_+_72498029 1.41 ENSMUST00000021148.13
ENSMUST00000138247.8
ubiquitin-conjugating enzyme E2G 1
chr19_-_10582773 1.41 ENSMUST00000237788.2
triokinase, FMN cyclase
chr8_-_105122397 1.39 ENSMUST00000179802.2
CKLF-like MARVEL transmembrane domain containing 4
chrX_-_7440480 1.37 ENSMUST00000115742.9
ENSMUST00000150787.8
protein phosphatase 1, regulatory subunit 3F
chr5_+_141227245 1.35 ENSMUST00000085774.11
sidekick cell adhesion molecule 1
chr2_-_35994819 1.34 ENSMUST00000148852.4
LIM homeobox protein 6
chr15_+_99489018 1.32 ENSMUST00000229728.2
ENSMUST00000231163.2
aquaporin 5
chr14_-_19057159 1.31 ENSMUST00000170123.2
predicted gene 10409
chr11_+_11065782 1.31 ENSMUST00000056344.5
von Willebrand factor C domain containing 2
chr2_-_32178034 1.29 ENSMUST00000183946.8
ENSMUST00000113400.3
ENSMUST00000050410.11
SWI5 recombination repair homolog (yeast)
chr14_+_15295240 1.28 ENSMUST00000172431.8
predicted gene 3512
chr5_-_34445751 1.28 ENSMUST00000114368.2
zinc finger, FYVE domain containing 28
chr1_+_74430575 1.28 ENSMUST00000027367.14
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr3_+_9315662 1.27 ENSMUST00000155203.2
zinc finger and BTB domain containing 10
chr7_-_127308059 1.27 ENSMUST00000061468.9
B cell CLL/lymphoma 7C
chr11_+_69826603 1.26 ENSMUST00000018698.12
Y box protein 2
chr4_+_152093260 1.26 ENSMUST00000097773.4
kelch-like 21
chr2_+_91087668 1.25 ENSMUST00000111349.9
ENSMUST00000131711.8
protein kinase C and casein kinase substrate in neurons 3
chr17_+_37253916 1.25 ENSMUST00000173072.2
ring finger protein 39
chr10_+_11219117 1.24 ENSMUST00000069106.5
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr15_+_34837501 1.23 ENSMUST00000072868.5
K+ voltage-gated channel, subfamily S, 2
chr13_+_31809774 1.22 ENSMUST00000042054.3
forkhead box F2
chr4_-_114766070 1.20 ENSMUST00000068654.5
forkhead box D2
chr14_+_15579811 1.20 ENSMUST00000171906.2
predicted gene 3667
chr16_-_38533597 1.20 ENSMUST00000023487.5
Rho GTPase activating protein 31
chr4_+_48279794 1.20 ENSMUST00000030029.10
inversin
chr11_+_49916136 1.19 ENSMUST00000054684.14
ENSMUST00000238748.2
ENSMUST00000102776.5
ring finger protein 130
chr2_+_122461079 1.19 ENSMUST00000239506.1
spermatosis associated 5-like 1
chr15_-_82872073 1.18 ENSMUST00000229439.2
transcription factor 20
chr14_-_16968099 1.18 ENSMUST00000181562.8
predicted gene, 3488
chr7_+_36397426 1.16 ENSMUST00000021641.8
teashirt zinc finger family member 3
chr13_-_92268156 1.16 ENSMUST00000151408.9
ENSMUST00000216219.2
RAS protein-specific guanine nucleotide-releasing factor 2
chr11_+_117545618 1.15 ENSMUST00000106344.8
trinucleotide repeat containing 6C
chr14_-_24054352 1.14 ENSMUST00000190339.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_-_34856853 1.13 ENSMUST00000036584.13
pantothenate kinase 1
chr13_+_119565669 1.13 ENSMUST00000173627.8
ENSMUST00000126957.9
ENSMUST00000174691.8
polyadenylate binding protein-interacting protein 1
chr17_+_26934617 1.12 ENSMUST00000062519.14
ENSMUST00000144221.2
ENSMUST00000142539.8
ENSMUST00000151681.2
CREB3 regulatory factor
chr7_+_101859542 1.12 ENSMUST00000140631.2
ENSMUST00000120879.8
ENSMUST00000146996.8
post-GPI attachment to proteins 2
chrX_-_73067514 1.11 ENSMUST00000033769.15
ENSMUST00000114352.8
ENSMUST00000068286.12
ENSMUST00000114360.10
ENSMUST00000114354.10
interleukin-1 receptor-associated kinase 1
chr18_+_82929037 1.11 ENSMUST00000236858.2
zinc finger protein 516
chr7_+_128858730 1.10 ENSMUST00000094018.6
ENSMUST00000205896.2
phospholipid phosphatase 4
chr18_+_36414122 1.09 ENSMUST00000051301.6
purine rich element binding protein A
chr6_+_107506678 1.08 ENSMUST00000049285.10
leucine rich repeat protein 1, neuronal
chr3_-_107366868 1.08 ENSMUST00000009617.10
ENSMUST00000238670.2
potassium voltage gated channel, Shaw-related subfamily, member 4
chr11_+_108811168 1.08 ENSMUST00000052915.14
axin 2
chr1_+_59521583 1.07 ENSMUST00000114246.4
frizzled class receptor 7
chr13_-_60324755 1.07 ENSMUST00000223933.2
growth arrest specific 1
chr15_+_39061612 1.06 ENSMUST00000082054.12
ENSMUST00000227243.2
ENSMUST00000042917.10
regulating synaptic membrane exocytosis 2
chr13_+_43070127 1.06 ENSMUST00000239286.2
phosphatase and actin regulator 1
chrX_-_73067351 1.05 ENSMUST00000114353.10
ENSMUST00000101458.9
interleukin-1 receptor-associated kinase 1
chr1_-_157240138 1.05 ENSMUST00000078308.13
RAS protein activator like 2
chr7_+_141047298 1.04 ENSMUST00000106000.10
ENSMUST00000209892.2
ENSMUST00000177840.9
CD151 antigen
chr7_+_141047416 1.04 ENSMUST00000209988.2
CD151 antigen
chr2_-_80411578 1.02 ENSMUST00000028386.12
NCK-associated protein 1
chr13_-_31743316 1.01 ENSMUST00000170573.2
RIKEN cDNA A530084C06 gene
chr7_+_141055135 1.01 ENSMUST00000026585.14
tetraspanin 4
chr4_+_11156411 1.01 ENSMUST00000029865.4
transformation related protein 53 inducible nuclear protein 1
chr15_+_76227695 1.01 ENSMUST00000023210.8
ENSMUST00000231045.2
cytochrome c-1
chr14_-_18135010 1.00 ENSMUST00000165466.8
RIKEN cDNA 2610042L04 gene
chr5_-_24806960 0.99 ENSMUST00000030791.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_-_76452365 0.99 ENSMUST00000075159.5
circadian locomotor output cycles kaput
chr13_+_73775001 0.98 ENSMUST00000022104.9
telomerase reverse transcriptase
chr17_-_85995680 0.98 ENSMUST00000024947.8
ENSMUST00000163568.4
sine oculis-related homeobox 2
chr4_-_45530330 0.98 ENSMUST00000061986.12
src homology 2 domain-containing transforming protein B
chr15_+_34838195 0.97 ENSMUST00000228725.2
K+ voltage-gated channel, subfamily S, 2
chr3_-_104127676 0.96 ENSMUST00000064371.14
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr2_+_84489890 0.96 ENSMUST00000133437.3
BTB (POZ) domain containing 18
chr14_-_18897750 0.96 ENSMUST00000178728.2
predicted gene 3005
chr14_-_18659699 0.96 ENSMUST00000170480.8
predicted gene 3002
chr18_+_82929451 0.94 ENSMUST00000235902.2
zinc finger protein 516
chr12_+_95658987 0.94 ENSMUST00000057324.4
fibronectin leucine rich transmembrane protein 2
chr8_+_108020132 0.93 ENSMUST00000151114.8
ENSMUST00000125721.8
ENSMUST00000075922.11
nuclear factor of activated T cells 5
chr5_-_37981919 0.93 ENSMUST00000063116.10
msh homeobox 1
chr6_+_72333209 0.92 ENSMUST00000206531.2
transmembrane protein 150A
chr9_-_43117052 0.91 ENSMUST00000176636.5
POU domain, class 2, transcription factor 3
chr11_+_94218810 0.90 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr2_-_166838018 0.90 ENSMUST00000049412.12
staufen double-stranded RNA binding protein 1
chr14_-_24054273 0.89 ENSMUST00000188285.7
ENSMUST00000190044.7
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_+_82216800 0.89 ENSMUST00000222298.2
signal-induced proliferation-associated 1 like 1
chr3_-_104127419 0.88 ENSMUST00000121198.8
ENSMUST00000122303.2
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr5_+_135197228 0.88 ENSMUST00000111187.10
ENSMUST00000111188.5
ENSMUST00000202606.3
B cell CLL/lymphoma 7B
chr11_+_70431063 0.88 ENSMUST00000018429.12
ENSMUST00000108557.10
ENSMUST00000108556.2
phospholipase D2
chr3_+_37117676 0.88 ENSMUST00000144629.8
adenosine deaminase domain containing 1 (testis specific)
chr7_+_141055350 0.88 ENSMUST00000138092.8
ENSMUST00000146305.8
tetraspanin 4
chr3_+_37117779 0.88 ENSMUST00000029274.14
adenosine deaminase domain containing 1 (testis specific)
chr6_-_83433357 0.87 ENSMUST00000186548.7
tet methylcytosine dioxygenase 3
chr11_+_59197746 0.87 ENSMUST00000000128.10
ENSMUST00000108783.4
wingless-type MMTV integration site family, member 9A
chr2_-_73605684 0.87 ENSMUST00000112024.10
ENSMUST00000180045.8
chimerin 1
chrX_+_7439839 0.87 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr2_-_166838182 0.85 ENSMUST00000109238.9
ENSMUST00000109235.8
ENSMUST00000109236.9
staufen double-stranded RNA binding protein 1
chr7_-_132724344 0.85 ENSMUST00000167218.8
C-terminal binding protein 2
chr11_+_77821626 0.84 ENSMUST00000093995.10
ENSMUST00000000646.14
seizure related gene 6
chr10_-_127502541 0.84 ENSMUST00000026469.9
Ngfi-A binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2d

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.3 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
2.2 15.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
1.4 4.1 GO:0003167 atrioventricular bundle cell differentiation(GO:0003167)
1.3 6.5 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
1.2 7.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
1.1 6.7 GO:0032902 nerve growth factor production(GO:0032902)
1.0 4.1 GO:0042851 L-alanine metabolic process(GO:0042851)
0.9 2.7 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.9 3.6 GO:0015755 fructose transport(GO:0015755)
0.9 2.6 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.6 6.7 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.5 1.6 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.5 4.3 GO:0002432 granuloma formation(GO:0002432)
0.5 1.6 GO:0021644 vagus nerve morphogenesis(GO:0021644)
0.5 1.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 2.9 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.5 2.8 GO:2000054 regulation of mismatch repair(GO:0032423) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.4 1.8 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.4 2.7 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.4 1.7 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.4 1.2 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.4 1.5 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.4 1.1 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.3 0.7 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.3 1.0 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.3 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.0 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.3 5.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 0.9 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.3 2.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 0.9 GO:0002660 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.3 4.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 0.8 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.3 1.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 1.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.3 1.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.3 1.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 2.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 1.0 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.2 1.5 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.2 4.4 GO:0045176 apical protein localization(GO:0045176)
0.2 1.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.2 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.2 2.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 1.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 0.8 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 0.6 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 0.6 GO:0048320 axial mesoderm formation(GO:0048320)
0.2 1.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.7 GO:0021564 vagus nerve development(GO:0021564)
0.2 0.5 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.2 0.9 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.2 1.5 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 0.6 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.2 0.9 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.2 1.5 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 1.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 1.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.2 GO:0046959 habituation(GO:0046959)
0.1 1.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.4 GO:0015881 creatine transport(GO:0015881)
0.1 0.8 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 3.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.6 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 2.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.0 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.5 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 1.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 1.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 1.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 1.5 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.7 GO:0035106 operant conditioning(GO:0035106)
0.1 0.5 GO:0042414 epinephrine metabolic process(GO:0042414)
0.1 3.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.1 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 1.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 2.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 2.1 GO:0060539 diaphragm development(GO:0060539)
0.1 3.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.0 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.7 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 0.2 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 2.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 4.5 GO:0035690 cellular response to drug(GO:0035690)
0.1 1.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.4 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.6 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 2.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 3.7 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 1.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.3 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.7 GO:0060746 parental behavior(GO:0060746)
0.0 0.3 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 1.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 1.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 1.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.7 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 1.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.3 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0061038 estradiol secretion(GO:0035938) uterus morphogenesis(GO:0061038) regulation of estradiol secretion(GO:2000864)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.7 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.2 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.6 GO:0046039 GTP metabolic process(GO:0046039)
0.0 2.0 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.3 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 2.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.7 3.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 1.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 1.0 GO:0098830 presynaptic endosome(GO:0098830)
0.3 1.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 3.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 15.4 GO:0031901 early endosome membrane(GO:0031901)
0.2 17.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 2.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.3 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 4.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.3 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:0097632 extrinsic component of pre-autophagosomal structure membrane(GO:0097632)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 4.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0001940 male pronucleus(GO:0001940)
0.1 1.7 GO:0032433 filopodium tip(GO:0032433)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.6 GO:0071437 invadopodium(GO:0071437)
0.1 0.3 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 1.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 5.1 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 3.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.9 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 5.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 4.4 GO:0031514 motile cilium(GO:0031514)
0.0 2.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.5 GO:0055037 recycling endosome(GO:0055037)
0.0 1.3 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 4.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 7.2 GO:0043235 receptor complex(GO:0043235)
0.0 4.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0005901 caveola(GO:0005901)
0.0 5.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.3 GO:0005770 late endosome(GO:0005770)
0.0 0.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
1.2 3.6 GO:0005353 fructose transmembrane transporter activity(GO:0005353) uniporter activity(GO:0015292)
1.0 2.9 GO:0050354 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
0.8 4.1 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.8 6.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.7 2.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.7 2.1 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.6 3.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.5 1.6 GO:0005369 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.5 1.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.4 1.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.4 2.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 4.5 GO:0008494 translation activator activity(GO:0008494)
0.4 6.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.4 1.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 1.7 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 2.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 1.2 GO:2001070 starch binding(GO:2001070)
0.3 2.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 4.3 GO:0043495 protein anchor(GO:0043495)
0.3 1.4 GO:2001069 glycogen binding(GO:2001069)
0.3 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 3.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 0.7 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.2 1.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 2.8 GO:0070411 I-SMAD binding(GO:0070411)
0.2 7.9 GO:0070412 R-SMAD binding(GO:0070412)
0.2 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 2.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.8 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.5 GO:0043559 insulin binding(GO:0043559)
0.1 1.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.4 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 3.8 GO:0031489 myosin V binding(GO:0031489)
0.1 1.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 4.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.4 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1 1.0 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 2.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.5 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 4.1 GO:0005109 frizzled binding(GO:0005109)
0.1 1.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.3 GO:0015250 water channel activity(GO:0015250)
0.1 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 4.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 3.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 23.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 4.4 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 3.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.8 GO:0046332 SMAD binding(GO:0046332)
0.0 4.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 3.3 GO:0002020 protease binding(GO:0002020)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.3 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.1 GO:0034648 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 4.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 4.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 7.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 16.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 3.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 7.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 4.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 2.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 3.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 6.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 4.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 4.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 4.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 2.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1