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GSE58827: Dynamics of the Mouse Liver

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Results for Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 0.41

Motif logo

Transcription factors associated with Vsx1_Uncx_Prrx2_Shox2_Noto

Gene Symbol Gene ID Gene Info
ENSMUSG00000033080.10 visual system homeobox 1
ENSMUSG00000029546.13 UNC homeobox
ENSMUSG00000039476.14 paired related homeobox 2
ENSMUSG00000027833.17 short stature homeobox 2
ENSMUSG00000068302.9 notochord homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Shox2mm39_v1_chr3_-_66888474_66888651-0.289.2e-02Click!
Prrx2mm39_v1_chr2_+_30724984_30724984-0.105.7e-01Click!
Uncxmm39_v1_chr5_+_139529643_139529662-0.077.0e-01Click!
Vsx1mm39_v1_chr2_-_150531280_1505312800.029.0e-01Click!

Activity profile of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Sorted Z-values of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_138056914 2.44 ENSMUST00000171804.4
solute carrier family 15, member 5
chr14_-_118289557 0.84 ENSMUST00000022725.4
dopachrome tautomerase
chr12_-_25147139 0.80 ENSMUST00000221761.2
inhibitor of DNA binding 2
chr5_+_115373895 0.77 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr5_+_14075281 0.75 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chrX_+_132751729 0.58 ENSMUST00000033602.9
tenomodulin
chr4_-_14621805 0.53 ENSMUST00000042221.14
solute carrier family 26, member 7
chr9_+_118307412 0.51 ENSMUST00000035020.15
eomesodermin
chr5_-_77262968 0.50 ENSMUST00000081964.7
HOP homeobox
chr4_-_14621669 0.50 ENSMUST00000143105.2
solute carrier family 26, member 7
chr6_-_30936013 0.48 ENSMUST00000101589.5
Kruppel-like factor 14
chr3_+_59989282 0.46 ENSMUST00000029326.6
succinate receptor 1
chr6_-_41752111 0.46 ENSMUST00000214976.3
olfactory receptor 459
chr14_-_64654397 0.44 ENSMUST00000210428.2
methionine sulfoxide reductase A
chrM_+_2743 0.44 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr6_-_115569504 0.44 ENSMUST00000112957.2
makorin, ring finger protein 2, opposite strand
chr9_+_118307250 0.43 ENSMUST00000111763.8
eomesodermin
chr18_+_57601541 0.43 ENSMUST00000091892.4
ENSMUST00000209782.2
cortexin 3
chr1_+_74324089 0.43 ENSMUST00000113805.8
ENSMUST00000027370.13
ENSMUST00000087226.11
paroxysmal nonkinesiogenic dyskinesia
chr8_-_5155347 0.41 ENSMUST00000023835.3
solute carrier family 10, member 2
chr2_+_124978518 0.40 ENSMUST00000238754.2
cortexin 2
chr14_+_26722319 0.40 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr4_-_154721288 0.38 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr14_-_68771138 0.38 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr4_-_97666279 0.38 ENSMUST00000146447.8
RIKEN cDNA E130114P18 gene
chr6_-_147165623 0.38 ENSMUST00000052296.9
ENSMUST00000204197.2
parathyroid hormone-like peptide
chr14_-_64654592 0.38 ENSMUST00000210363.2
methionine sulfoxide reductase A
chr4_+_109835224 0.37 ENSMUST00000061187.4
doublesex and mab-3 related transcription factor like family A2
chr10_+_127734384 0.37 ENSMUST00000047134.8
4short chain dehydrogenase/reductase family 9C, member 7
chr11_-_87249837 0.37 ENSMUST00000055438.5
protein phosphatase 1E (PP2C domain containing)
chr4_+_135870808 0.36 ENSMUST00000008016.3
inhibitor of DNA binding 3
chrX_-_142716085 0.36 ENSMUST00000087313.10
doublecortin
chr15_+_92495007 0.36 ENSMUST00000035399.10
PDZ domain containing RING finger 4
chr18_+_56565188 0.35 ENSMUST00000070166.6
GRAM domain containing 3
chr2_+_124978612 0.34 ENSMUST00000099452.3
ENSMUST00000238377.2
cortexin 2
chr7_+_51528788 0.34 ENSMUST00000107591.9
growth arrest specific 2
chr15_+_39522905 0.34 ENSMUST00000226410.2
regulating synaptic membrane exocytosis 2
chr8_-_3675274 0.34 ENSMUST00000004749.7
Purkinje cell protein 2 (L7)
chr7_+_114344920 0.33 ENSMUST00000136645.8
ENSMUST00000169913.8
INSC spindle orientation adaptor protein
chr7_-_99512558 0.33 ENSMUST00000207137.2
ENSMUST00000207063.2
ENSMUST00000207580.2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr3_+_93301003 0.32 ENSMUST00000045912.3
repetin
chr2_+_27055245 0.32 ENSMUST00000000910.7
dopamine beta hydroxylase
chr5_+_104350475 0.32 ENSMUST00000066708.7
dentin matrix protein 1
chr13_-_103042554 0.32 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr10_+_85763545 0.32 ENSMUST00000170396.3
achaete-scute family bHLH transcription factor 4
chr7_-_12829100 0.32 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chrM_+_7006 0.31 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr10_+_128173603 0.30 ENSMUST00000005826.9
citrate synthase
chr11_+_116734104 0.30 ENSMUST00000106370.10
methyltransferase like 23
chrX_+_110808231 0.30 ENSMUST00000207546.2
predicted gene 45194
chr10_+_50770836 0.30 ENSMUST00000219436.2
single-minded family bHLH transcription factor 1
chr8_-_3674993 0.30 ENSMUST00000142431.8
Purkinje cell protein 2 (L7)
chr4_-_14621497 0.29 ENSMUST00000149633.2
solute carrier family 26, member 7
chrX_+_149330371 0.29 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr11_-_59466995 0.29 ENSMUST00000215339.2
ENSMUST00000214351.2
olfactory receptor 222
chr18_+_23548192 0.28 ENSMUST00000222515.2
dystrobrevin alpha
chr11_+_70410009 0.28 ENSMUST00000057685.3
glycolipid transfer protein domain containing 2
chr7_-_44752508 0.28 ENSMUST00000209830.2
Fc fragment of IgG receptor and transporter
chr13_-_53627110 0.27 ENSMUST00000021922.10
msh homeobox 2
chr13_-_43634695 0.27 ENSMUST00000144326.4
RAN binding protein 9
chrX_+_159551009 0.27 ENSMUST00000033650.14
retinoschisis (X-linked, juvenile) 1 (human)
chr1_-_158183894 0.27 ENSMUST00000004133.11
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr13_-_103042294 0.26 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr9_+_24194729 0.26 ENSMUST00000154644.2
neuropeptide S receptor 1
chr11_+_70410445 0.26 ENSMUST00000179000.2
glycolipid transfer protein domain containing 2
chr10_+_101994841 0.26 ENSMUST00000020039.13
MGAT4 family, member C
chr7_+_65343156 0.26 ENSMUST00000032726.14
ENSMUST00000107495.5
ENSMUST00000143508.3
ENSMUST00000129166.3
ENSMUST00000206517.2
ENSMUST00000206837.2
ENSMUST00000206628.2
ENSMUST00000206361.2
TM2 domain containing 3
chr1_-_163552693 0.26 ENSMUST00000159679.8
methyltransferase like 11B
chr14_-_36820304 0.26 ENSMUST00000022337.11
cadherin-related family member 1
chr3_+_125197722 0.25 ENSMUST00000173932.8
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr17_-_84154196 0.25 ENSMUST00000234214.2
3-hydroxyanthranilate 3,4-dioxygenase
chr5_-_86521273 0.25 ENSMUST00000031175.12
transmembrane protease, serine 11d
chr11_-_43792013 0.25 ENSMUST00000067258.9
ENSMUST00000139906.2
adrenergic receptor, alpha 1b
chr18_+_24737009 0.25 ENSMUST00000234266.2
ENSMUST00000025120.8
elongator acetyltransferase complex subunit 2
chr2_+_9887427 0.25 ENSMUST00000114919.2
RIKEN cDNA 4930412O13 gene
chr7_-_49286594 0.25 ENSMUST00000032717.7
developing brain homeobox 1
chr16_+_43323970 0.24 ENSMUST00000126100.8
ENSMUST00000123047.8
ENSMUST00000156981.8
zinc finger and BTB domain containing 20
chr9_+_55448432 0.24 ENSMUST00000034869.11
insulin related protein 2 (islet 2)
chr3_+_108000425 0.24 ENSMUST00000151326.8
guanine nucleotide binding protein, alpha transducing 2
chr14_-_109151590 0.24 ENSMUST00000100322.4
SLIT and NTRK-like family, member 1
chr17_-_84154173 0.24 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr12_+_111780604 0.24 ENSMUST00000021714.9
ENSMUST00000223211.2
ENSMUST00000222843.2
ENSMUST00000221375.2
zinc finger, FYVE domain containing 21
chr11_+_6366259 0.23 ENSMUST00000213200.2
peptidylprolyl isomerase A
chr5_+_139529643 0.23 ENSMUST00000174792.2
UNC homeobox
chr9_-_37580478 0.23 ENSMUST00000011262.4
pannexin 3
chr13_+_118851214 0.23 ENSMUST00000022246.9
fibroblast growth factor 10
chr5_+_108842294 0.23 ENSMUST00000013633.12
fibroblast growth factor receptor-like 1
chr12_-_11258973 0.23 ENSMUST00000049877.3
mesogenin 1
chr16_-_45544960 0.22 ENSMUST00000096057.5
transgelin 3
chr19_-_13827773 0.22 ENSMUST00000215350.2
olfactory receptor 1501
chr8_-_3675024 0.22 ENSMUST00000133459.8
Purkinje cell protein 2 (L7)
chr15_-_50753792 0.22 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chr6_-_145811028 0.22 ENSMUST00000111703.2
basic helix-loop-helix family, member e41
chr1_-_74924481 0.21 ENSMUST00000159232.2
ENSMUST00000068631.4
FEV transcription factor, ETS family member
chr13_+_22563988 0.21 ENSMUST00000227685.2
ENSMUST00000227689.2
ENSMUST00000227846.2
vomeronasal 1 receptor 199
chr11_+_115225557 0.21 ENSMUST00000106543.8
ENSMUST00000019006.5
otopetrin 3
chrX_+_159551171 0.21 ENSMUST00000112368.3
retinoschisis (X-linked, juvenile) 1 (human)
chr5_+_35156454 0.21 ENSMUST00000114283.8
regulator of G-protein signaling 12
chr19_-_13828056 0.21 ENSMUST00000208493.3
olfactory receptor 1501
chr18_-_81029986 0.21 ENSMUST00000057950.9
spalt like transcription factor 3
chr15_-_103123711 0.20 ENSMUST00000122182.2
ENSMUST00000108813.10
ENSMUST00000127191.2
chromobox 5
chr15_-_34356567 0.20 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr3_+_55369149 0.20 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr10_-_12689345 0.20 ENSMUST00000217899.2
utrophin
chr1_-_14374842 0.20 ENSMUST00000188857.7
ENSMUST00000185453.7
EYA transcriptional coactivator and phosphatase 1
chrX_-_142716200 0.20 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr13_-_23041731 0.20 ENSMUST00000228645.2
vomeronasal 1 receptor 211
chr12_+_38830812 0.20 ENSMUST00000160856.8
ets variant 1
chr1_-_72323464 0.19 ENSMUST00000027381.13
peroxisomal trans-2-enoyl-CoA reductase
chr15_+_21111428 0.19 ENSMUST00000075132.8
cadherin 12
chr17_+_17622934 0.19 ENSMUST00000115576.3
limb and CNS expressed 1
chr1_-_14374794 0.19 ENSMUST00000190337.7
EYA transcriptional coactivator and phosphatase 1
chr1_-_9369463 0.19 ENSMUST00000140295.8
syntrophin, gamma 1
chr18_-_3280999 0.19 ENSMUST00000049942.13
cAMP responsive element modulator
chr1_-_9368721 0.19 ENSMUST00000132064.8
syntrophin, gamma 1
chr2_-_17465410 0.18 ENSMUST00000145492.2
nebulette
chr18_+_23548534 0.18 ENSMUST00000221880.2
ENSMUST00000220904.2
ENSMUST00000047954.15
dystrobrevin alpha
chr8_-_32408864 0.18 ENSMUST00000073884.7
ENSMUST00000238812.2
neuregulin 1
chr1_-_9369045 0.18 ENSMUST00000191683.6
syntrophin, gamma 1
chr8_-_62576140 0.18 ENSMUST00000034052.14
ENSMUST00000034054.9
annexin A10
chr3_+_68479578 0.18 ENSMUST00000170788.9
schwannomin interacting protein 1
chr7_+_43430459 0.18 ENSMUST00000014058.11
kallikrein related-peptidase 10
chr7_+_49559859 0.18 ENSMUST00000056442.12
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr2_+_162829422 0.17 ENSMUST00000117123.2
serum/glucocorticoid regulated kinase 2
chr3_-_72875187 0.17 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr7_+_138828391 0.17 ENSMUST00000093993.5
ENSMUST00000172136.9
PWWP domain containing 2B
chr2_+_83554770 0.17 ENSMUST00000141725.3
integrin alpha V
chr3_-_154760978 0.17 ENSMUST00000064076.6
TNNI3 interacting kinase
chr16_+_42727926 0.17 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr18_+_23548455 0.17 ENSMUST00000115832.4
dystrobrevin alpha
chr1_+_88234454 0.17 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr7_-_115423934 0.17 ENSMUST00000169129.8
SRY (sex determining region Y)-box 6
chr4_-_58499398 0.17 ENSMUST00000107570.2
lysophosphatidic acid receptor 1
chr2_+_162829250 0.17 ENSMUST00000018012.14
serum/glucocorticoid regulated kinase 2
chr7_-_46316767 0.17 ENSMUST00000168335.3
ENSMUST00000107669.9
tryptophan hydroxylase 1
chr4_+_97665992 0.17 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr13_+_8252895 0.17 ENSMUST00000064473.13
adenosine deaminase, RNA-specific, B2
chr4_-_155141241 0.17 ENSMUST00000131173.3
phospholipase C, eta 2
chr3_-_92031247 0.16 ENSMUST00000070284.4
proline rich 9
chr7_+_99512701 0.16 ENSMUST00000207855.2
X-ray radiation resistance associated 1
chr2_-_63014514 0.16 ENSMUST00000112452.2
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr10_+_73782857 0.16 ENSMUST00000191709.6
ENSMUST00000193739.6
ENSMUST00000195531.6
protocadherin 15
chr14_-_110992533 0.16 ENSMUST00000078386.4
SLIT and NTRK-like family, member 6
chr2_-_18053595 0.16 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr2_-_87543523 0.16 ENSMUST00000214209.2
olfactory receptor 1137
chr6_+_145879839 0.16 ENSMUST00000032383.14
sarcospan
chr19_-_42117420 0.16 ENSMUST00000161873.2
ENSMUST00000018965.4
arginine vasopressin-induced 1
chr6_+_8948608 0.16 ENSMUST00000160300.2
neurexophilin 1
chr5_-_66672158 0.16 ENSMUST00000161879.8
ENSMUST00000159357.8
amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_-_72323407 0.16 ENSMUST00000097698.5
peroxisomal trans-2-enoyl-CoA reductase
chr1_+_104696235 0.16 ENSMUST00000062528.9
cadherin 20
chr10_-_107330580 0.16 ENSMUST00000044210.5
myogenic factor 6
chr4_-_110149916 0.15 ENSMUST00000106601.8
ELAV like RNA binding protein 4
chr7_-_37472290 0.15 ENSMUST00000176205.8
zinc finger protein 536
chr13_+_8252957 0.15 ENSMUST00000123187.2
adenosine deaminase, RNA-specific, B2
chr19_-_11816583 0.15 ENSMUST00000214887.2
olfactory receptor 1417
chr4_+_13751297 0.15 ENSMUST00000105566.9
RUNX1 translocation partner 1
chr13_-_21798192 0.15 ENSMUST00000051874.6
olfactory receptor 1362
chr13_+_22508759 0.15 ENSMUST00000226225.2
ENSMUST00000227017.2
vomeronasal 1 receptor 197
chr13_+_111391544 0.15 ENSMUST00000054716.4
actin, beta-like 2
chr17_+_49922129 0.15 ENSMUST00000162854.2
kinesin family member 6
chr9_+_96140750 0.15 ENSMUST00000186609.7
transcription factor Dp 2
chr6_+_63232955 0.15 ENSMUST00000095852.5
glutamate receptor, ionotropic, delta 2
chr1_+_53100796 0.15 ENSMUST00000027269.7
ENSMUST00000191197.2
myostatin
chr11_-_99412162 0.15 ENSMUST00000107445.8
keratin 39
chr8_+_23114035 0.15 ENSMUST00000033936.8
dickkopf WNT signaling pathway inhibitor 4
chr1_-_14380327 0.14 ENSMUST00000080664.14
EYA transcriptional coactivator and phosphatase 1
chr6_+_29853745 0.14 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr11_-_99412084 0.14 ENSMUST00000076948.2
keratin 39
chr10_+_126911134 0.14 ENSMUST00000239120.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr12_+_108145802 0.14 ENSMUST00000221167.2
cyclin K
chr2_+_177969456 0.14 ENSMUST00000133267.3
phosphatase and actin regulator 3
chr15_-_101482320 0.14 ENSMUST00000042957.6
keratin 75
chr3_-_86455575 0.14 ENSMUST00000077524.4
mab-21-like 2
chr6_-_138404076 0.14 ENSMUST00000203435.3
LIM domain only 3
chr19_+_59446804 0.14 ENSMUST00000062216.4
empty spiracles homeobox 2
chr3_-_50398027 0.14 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chrX_-_156198282 0.14 ENSMUST00000079945.11
ENSMUST00000138396.3
phosphate regulating endopeptidase homolog, X-linked
chr8_-_32440071 0.14 ENSMUST00000207678.3
neuregulin 1
chr2_+_61634797 0.14 ENSMUST00000048934.15
T-box brain transcription factor 1
chr10_+_101994719 0.14 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
MGAT4 family, member C
chr8_+_46111703 0.14 ENSMUST00000134675.8
ENSMUST00000139869.8
ENSMUST00000126067.8
sorbin and SH3 domain containing 2
chr1_-_92446141 0.14 ENSMUST00000189174.2
olfactory receptor 1414
chr2_+_57887896 0.14 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr8_-_85573489 0.14 ENSMUST00000003912.7
calreticulin
chr2_-_86857424 0.14 ENSMUST00000214857.2
ENSMUST00000215972.2
olfactory receptor 1104
chr11_+_94218810 0.13 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr13_+_23431304 0.13 ENSMUST00000235331.2
ENSMUST00000236495.2
ENSMUST00000238002.2
vomeronasal 1 receptor 223
chr5_+_104318542 0.13 ENSMUST00000112771.2
dentin sialophosphoprotein
chr12_+_38831093 0.13 ENSMUST00000161513.9
ets variant 1
chr8_+_121842902 0.13 ENSMUST00000054691.8
forkhead box C2
chr15_-_66985760 0.13 ENSMUST00000092640.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr18_-_81029751 0.13 ENSMUST00000238808.2
spalt like transcription factor 3
chr7_-_37472979 0.13 ENSMUST00000176534.8
zinc finger protein 536
chr3_-_130524024 0.13 ENSMUST00000079085.11
ribosomal protein L34
chr2_-_86109346 0.13 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr10_-_23977810 0.13 ENSMUST00000170267.3
trace amine-associated receptor 8C
chr1_+_161322219 0.13 ENSMUST00000086084.2
tumor necrosis factor (ligand) superfamily, member 18
chr18_-_57108405 0.13 ENSMUST00000139243.9
ENSMUST00000025488.15
RIKEN cDNA C330018D20 gene
chr1_+_172383499 0.13 ENSMUST00000061835.10
V-set and immunoglobulin domain containing 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.3 0.8 GO:0001966 thigmotaxis(GO:0001966)
0.2 0.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 1.3 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:0060618 nipple development(GO:0060618)
0.1 0.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.5 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 1.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.3 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 0.4 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.3 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.8 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0061033 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.2 GO:0048880 hindbrain tangential cell migration(GO:0021934) sensory system development(GO:0048880)
0.1 0.3 GO:2000293 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 0.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.5 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.5 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0035934 corticosterone secretion(GO:0035934)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.4 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:2000722 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.0 0.1 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0072144 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.2 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) positive regulation of inhibitory postsynaptic potential(GO:0097151) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0090336 negative regulation of granulocyte differentiation(GO:0030853) positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.9 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 1.5 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.0 GO:0006649 phospholipid transfer to membrane(GO:0006649)
0.0 0.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016014 dystrobrevin complex(GO:0016014)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.1 0.3 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.0 0.1 GO:0002095 caveolar macromolecular signaling complex(GO:0002095)
0.0 0.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.2 0.8 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.3 GO:0016232 HNK-1 sulfotransferase activity(GO:0016232)
0.1 0.3 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.2 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0071820 N-box binding(GO:0071820)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0005118 sevenless binding(GO:0005118)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0019825 oxygen binding(GO:0019825)
0.0 1.5 GO:0005550 pheromone binding(GO:0005550)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.0 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions