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GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb12

Z-value: 0.42

Motif logo

Transcription factors associated with Zbtb12

Gene Symbol Gene ID Gene Info
ENSMUSG00000049823.10 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb12mm39_v1_chr17_+_35113490_35113554-0.307.3e-02Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_25239229 2.30 ENSMUST00000044547.10
ENSMUST00000066503.14
ENSMUST00000064862.13
carcinoembryonic antigen-related cell adhesion molecule 2
chr7_-_25176959 1.36 ENSMUST00000098668.3
ENSMUST00000206687.2
ENSMUST00000206676.2
ENSMUST00000205308.2
ENSMUST00000098669.8
ENSMUST00000206171.2
ENSMUST00000098666.9
carcinoembryonic antigen-related cell adhesion molecule 1
chr15_-_60793115 1.30 ENSMUST00000096418.5
alpha-1-B glycoprotein
chr11_-_70590923 1.20 ENSMUST00000108543.4
ENSMUST00000108542.8
ENSMUST00000108541.9
ENSMUST00000126114.9
ENSMUST00000073625.8
inhibitor of CDK, cyclin A1 interacting protein 1
chr19_-_8196196 1.20 ENSMUST00000113298.9
solute carrier family 22. member 29
chr17_+_37253802 0.92 ENSMUST00000040498.12
ring finger protein 39
chr2_+_43445333 0.88 ENSMUST00000028223.9
ENSMUST00000112826.8
kynureninase
chr2_+_30254239 0.87 ENSMUST00000077977.14
ENSMUST00000140075.9
ENSMUST00000142801.8
ENSMUST00000100214.10
mitoguardin 2
chr11_+_70591299 0.80 ENSMUST00000152618.9
ENSMUST00000102554.8
ENSMUST00000094499.11
ENSMUST00000072187.12
ENSMUST00000137119.3
kinesin family member 1C
chr6_+_90439544 0.75 ENSMUST00000032174.12
Kruppel-like factor 15
chr6_+_90439596 0.75 ENSMUST00000203039.3
Kruppel-like factor 15
chr2_+_43445359 0.73 ENSMUST00000050511.7
kynureninase
chr7_-_48493388 0.67 ENSMUST00000167786.4
cysteine and glycine-rich protein 3
chr17_+_79934096 0.62 ENSMUST00000224618.2
regulator of microtubule dynamics 2
chr15_+_76544058 0.56 ENSMUST00000230451.2
kinesin family member C2
chr15_-_76543889 0.54 ENSMUST00000231152.2
cysteine and histidine rich 1
chr16_-_94657531 0.45 ENSMUST00000232562.2
ENSMUST00000165538.3
potassium inwardly-rectifying channel, subfamily J, member 6
chr4_-_45489794 0.44 ENSMUST00000146236.8
src homology 2 domain-containing transforming protein B
chr9_-_35030479 0.44 ENSMUST00000213526.2
ENSMUST00000215089.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr10_+_62896492 0.41 ENSMUST00000219687.2
ENSMUST00000219045.2
phenazine biosynthesis-like protein domain containing 1
chr14_+_67470884 0.40 ENSMUST00000176161.8
early B cell factor 2
chr6_+_37877413 0.38 ENSMUST00000120238.2
tripartite motif-containing 24
chr11_-_50806962 0.37 ENSMUST00000116378.8
ENSMUST00000109128.8
zinc finger protein 2
chr7_+_100966289 0.36 ENSMUST00000163799.9
ENSMUST00000164479.9
START domain containing 10
chr13_+_9326513 0.35 ENSMUST00000174552.8
disco interacting protein 2 homolog C
chr19_+_46561801 0.34 ENSMUST00000026011.8
sideroflexin 2
chr4_-_43669141 0.34 ENSMUST00000056474.7
family with sequence similarity 221, member B
chr19_-_57170725 0.34 ENSMUST00000133369.2
actin-binding LIM protein 1
chr9_-_58448224 0.33 ENSMUST00000039788.11
CD276 antigen
chr11_+_114743044 0.32 ENSMUST00000142262.2
G protein-coupled receptor, family C, group 5, member C
chr11_+_108271990 0.32 ENSMUST00000146050.2
ENSMUST00000152958.8
apolipoprotein H
chr4_+_43669266 0.30 ENSMUST00000107864.8
transmembrane protein 8B
chr17_+_37253916 0.30 ENSMUST00000173072.2
ring finger protein 39
chr6_-_124791259 0.28 ENSMUST00000172132.10
ENSMUST00000239432.2
triosephosphate isomerase 1
chr11_-_118021460 0.25 ENSMUST00000132685.9
dynein, axonemal, heavy chain 17
chr4_-_119031050 0.24 ENSMUST00000052715.10
ENSMUST00000179290.8
ENSMUST00000154226.2
zinc finger protein 691
chr17_-_28779678 0.24 ENSMUST00000114785.3
ENSMUST00000025062.5
colipase, pancreatic
chr3_-_131138541 0.23 ENSMUST00000090246.5
ENSMUST00000126569.2
sphingomyelin synthase 2
chr9_+_36604516 0.23 ENSMUST00000034620.5
acrosomal vesicle protein 1
chr6_-_24528012 0.22 ENSMUST00000023851.9
NADH:ubiquinone oxidoreductase subunit A5
chr14_-_70449438 0.21 ENSMUST00000227929.2
sorbin and SH3 domain containing 3
chr15_-_82238432 0.20 ENSMUST00000230494.2
ENSMUST00000023085.7
NADH:ubiquinone oxidoreductase subunit A6
chr8_-_107007596 0.20 ENSMUST00000212896.2
sphingomyelin phosphodiesterase 3, neutral
chr18_+_70605691 0.20 ENSMUST00000164223.8
StAR-related lipid transfer (START) domain containing 6
chr18_+_70605476 0.20 ENSMUST00000114959.9
StAR-related lipid transfer (START) domain containing 6
chr15_+_102412157 0.20 ENSMUST00000096145.5
predicted gene 10337
chr18_+_70605722 0.19 ENSMUST00000174118.8
StAR-related lipid transfer (START) domain containing 6
chr13_-_104365310 0.19 ENSMUST00000022226.6
peptidylprolyl isomerase domain and WD repeat containing 1
chr4_-_138351313 0.19 ENSMUST00000030533.12
von Willebrand factor A domain containing 5B1
chr6_+_108041998 0.18 ENSMUST00000049246.7
SET domain without mariner transposase fusion
chr4_+_119396913 0.18 ENSMUST00000137560.8
forkhead box J3
chr15_-_88838605 0.18 ENSMUST00000109371.8
tubulin tyrosine ligase-like family, member 8
chr18_+_70605630 0.17 ENSMUST00000168249.9
StAR-related lipid transfer (START) domain containing 6
chr9_+_38407097 0.17 ENSMUST00000214003.3
ENSMUST00000214264.3
olfactory receptor 907
chr11_+_97697128 0.17 ENSMUST00000138919.2
LIM and SH3 protein 1
chr10_-_85847697 0.16 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr3_+_121243395 0.16 ENSMUST00000198393.2
calponin 3, acidic
chr7_+_140427711 0.16 ENSMUST00000026555.12
outer dense fiber of sperm tails 3
chr7_+_140427729 0.16 ENSMUST00000106049.2
outer dense fiber of sperm tails 3
chr10_-_75658355 0.15 ENSMUST00000160211.2
glutathione S-transferase, theta 4
chr11_+_98337655 0.15 ENSMUST00000019456.5
growth factor receptor bound protein 7
chr13_+_76246853 0.15 ENSMUST00000091466.4
ENSMUST00000224386.2
tetratricopeptide repeat domain 37
chr2_-_150531280 0.15 ENSMUST00000046095.10
visual system homeobox 1
chr11_+_102775991 0.14 ENSMUST00000100369.4
family with sequence similarity 187, member A
chr10_+_63293284 0.14 ENSMUST00000105440.8
catenin (cadherin associated protein), alpha 3
chr17_-_32408431 0.13 ENSMUST00000087721.10
ENSMUST00000162117.3
epoxide hydrolase 3
chr1_-_161807205 0.13 ENSMUST00000162676.2
RIKEN cDNA 4930558K02 gene
chr11_+_100332709 0.13 ENSMUST00000001599.4
ENSMUST00000107395.3
kelch-like 10
chr13_-_92620507 0.13 ENSMUST00000040106.9
family with sequence similarity 151, member B
chr7_+_99825886 0.13 ENSMUST00000178946.9
potassium voltage-gated channel, Isk-related subfamily, gene 3
chr14_-_52728503 0.13 ENSMUST00000073571.6
olfactory receptor 1507
chr8_+_71156071 0.13 ENSMUST00000212436.2
IQ motif containing N
chr14_+_8555284 0.12 ENSMUST00000144914.3
predicted gene 281
chr17_-_15596230 0.12 ENSMUST00000014917.8
delta like canonical Notch ligand 1
chr1_-_75208734 0.12 ENSMUST00000180101.3
RIKEN cDNA A630095N17 gene
chr6_-_143892814 0.11 ENSMUST00000124233.7
ENSMUST00000144289.4
ENSMUST00000111748.8
SRY (sex determining region Y)-box 5
chr12_-_81615248 0.11 ENSMUST00000008582.4
a disintegrin and metallopeptidase domain 21
chr15_-_99372575 0.11 ENSMUST00000040313.6
BCDIN3 domain containing
chr6_+_24528143 0.11 ENSMUST00000031696.10
ankyrin repeat and SOCS box-containing 15
chr1_+_69866145 0.10 ENSMUST00000065425.12
ENSMUST00000113940.4
sperm associated antigen 16
chr8_-_43981143 0.10 ENSMUST00000080135.5
a disintegrin and metallopeptidase domain 26B
chr6_+_136528155 0.10 ENSMUST00000186742.2
activating transcription factor 7 interacting protein
chr7_+_102420428 0.10 ENSMUST00000213432.2
olfactory receptor 561
chr5_+_87955941 0.10 ENSMUST00000072539.12
ENSMUST00000113279.8
ENSMUST00000101057.8
ENSMUST00000197301.2
casein alpha s2-like B
chr3_-_153610528 0.10 ENSMUST00000190449.2
mutS homolog 4
chr3_-_153610368 0.09 ENSMUST00000188338.7
mutS homolog 4
chr9_-_40366966 0.09 ENSMUST00000165104.8
ENSMUST00000045682.7
GRAM domain containing 1B
chr14_+_79718604 0.09 ENSMUST00000040131.13
E74-like factor 1
chr9_-_122673080 0.09 ENSMUST00000203176.3
ENSMUST00000203656.3
ENSMUST00000204619.2
predicted gene, 35549
chr10_-_5144699 0.09 ENSMUST00000215467.2
spectrin repeat containing, nuclear envelope 1
chr7_-_35285001 0.09 ENSMUST00000069912.6
regulator of G-protein signalling 9 binding protein
chr2_-_111942878 0.08 ENSMUST00000217078.2
olfactory receptor 1315, pseudogene 1
chr5_+_96104775 0.08 ENSMUST00000023840.7
chemokine (C-X-C motif) ligand 13
chr5_+_11234174 0.08 ENSMUST00000168407.3
predicted gene 5861
chr15_+_89383799 0.08 ENSMUST00000109309.9
SH3 and multiple ankyrin repeat domains 3
chr3_+_5283606 0.08 ENSMUST00000026284.13
zinc finger homeodomain 4
chr12_+_111540920 0.08 ENSMUST00000075281.8
ENSMUST00000084953.13
MAP/microtubule affinity regulating kinase 3
chr3_-_152232389 0.08 ENSMUST00000200062.2
adenylate kinase 5
chr5_-_142515792 0.08 ENSMUST00000099400.3
poly (A) polymerase beta (testis specific)
chr11_-_59118988 0.08 ENSMUST00000163300.8
ENSMUST00000061242.8
ADP-ribosylation factor 1
chr15_-_76259126 0.08 ENSMUST00000071119.8
testis-specific serine kinase 5
chr14_+_26789345 0.07 ENSMUST00000226105.2
interleukin 17 receptor D
chr14_+_26414422 0.07 ENSMUST00000022433.12
dynein, axonemal, heavy chain 12
chr17_+_83658354 0.07 ENSMUST00000096766.12
ENSMUST00000049503.10
ENSMUST00000112363.10
ENSMUST00000234460.2
echinoderm microtubule associated protein like 4
chr7_+_65693350 0.07 ENSMUST00000206065.2
predicted gene 45213
chr18_-_20995980 0.07 ENSMUST00000224530.2
trafficking protein particle complex 8
chrX_+_106836189 0.06 ENSMUST00000101292.9
terminal nucleotidyltransferase 5D
chr5_-_22070602 0.06 ENSMUST00000030878.8
solute carrier family 26, member 5
chrX_-_36167148 0.06 ENSMUST00000239259.2
NF-kappaB repressing factor
chr14_+_54082691 0.06 ENSMUST00000103674.6
T cell receptor alpha variable 19
chr15_-_98796373 0.05 ENSMUST00000229775.2
ENSMUST00000023737.6
desert hedgehog
chr3_+_5283577 0.04 ENSMUST00000175866.8
zinc finger homeodomain 4
chr11_+_104983022 0.04 ENSMUST00000021029.6
EF-hand calcium binding domain 3
chr8_+_41205245 0.04 ENSMUST00000096663.5
a disintegrin and metallopeptidase domain 25 (testase 2)
chrX_+_93768175 0.04 ENSMUST00000101388.4
zinc finger, X-linked, duplicated B
chr17_-_57181420 0.04 ENSMUST00000043062.5
acyl-CoA synthetase bubblegum family member 2
chr4_-_133360749 0.03 ENSMUST00000084238.5
zinc finger, DHHC domain containing 18
chr10_-_70428611 0.03 ENSMUST00000162251.8
phytanoyl-CoA hydroxylase interacting protein-like
chr19_+_6130059 0.03 ENSMUST00000149347.8
ENSMUST00000143303.2
transmembrane protein 262
chr13_-_14787602 0.03 ENSMUST00000220621.2
mitochondrial ribosomal protein L32
chr3_-_84063067 0.03 ENSMUST00000047368.8
meiotic nuclear divisions 1
chr12_-_101924407 0.02 ENSMUST00000159883.2
ENSMUST00000160251.8
ENSMUST00000161011.8
ENSMUST00000021606.12
ataxin 3
chr9_+_37278647 0.02 ENSMUST00000051839.9
hepatocyte cell adhesion molecule
chr11_+_69881885 0.02 ENSMUST00000018711.15
gamma-aminobutyric acid receptor associated protein
chrX_+_41591476 0.02 ENSMUST00000115070.8
ENSMUST00000153948.2
SH2 domain containing 1A
chr17_+_27248233 0.02 ENSMUST00000053683.7
ENSMUST00000236222.2
gametogenetin binding protein 1
chr2_+_129854256 0.01 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr4_+_32983417 0.01 ENSMUST00000084747.6
Ras-related GTP binding D
chr9_-_78389006 0.01 ENSMUST00000042235.15
eukaryotic translation elongation factor 1 alpha 1
chr5_-_35836761 0.00 ENSMUST00000114233.3
HtrA serine peptidase 3
chr5_-_121641461 0.00 ENSMUST00000079368.5
a disintegrin and metallopeptidase domain 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 1.4 GO:0070237 positive regulation of activation-induced cell death of T cells(GO:0070237)
0.2 0.7 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.2 2.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.2 GO:0015747 urate transport(GO:0015747)
0.0 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.3 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 1.5 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 1.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.0 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005713 recombination nodule(GO:0005713)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 3.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.3 GO:0005118 sevenless binding(GO:0005118)
0.1 1.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling