GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Zbtb18 Links Ensembl NCBI MGI UniProt	ENSMUSG00000063659.12	zinc finger and BTB domain containing 18

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zbtb18	mm39_v1_chr1_+_177273226_177273387	-0.31	6.6e-02	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_-_112417633 Show fit	25.34	ENSMUST00000034435.7	Ctrb1 Links Ensembl NCBI MGI UniProt Show fit	chymotrypsinogen B1
chr8_-_106660470 Show fit	15.53	ENSMUST00000034368.8	Ctrl Links Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like
chr14_+_30608433 Show fit	10.23	ENSMUST00000120269.11 ENSMUST00000078490.14 ENSMUST00000006703.15	Itih4 Links Ensembl NCBI MGI UniProt Show fit	inter alpha-trypsin inhibitor, heavy chain 4
chr14_+_30608478 Show fit	10.11	ENSMUST00000168782.4	Itih4 Links Ensembl NCBI MGI UniProt Show fit	inter alpha-trypsin inhibitor, heavy chain 4
chr6_-_41012435 Show fit	10.08	ENSMUST00000031931.6	2210010C04Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2210010C04 gene
chr4_-_115353326 Show fit	9.81	ENSMUST00000030487.3	Cyp4a14 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 14
chr17_-_28779678 Show fit	8.48	ENSMUST00000114785.3 ENSMUST00000025062.5	Clps Links Ensembl NCBI MGI UniProt Show fit	colipase, pancreatic
chr17_-_12894716 Show fit	8.48	ENSMUST00000024596.10	Slc22a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 22 (organic cation transporter), member 1
chr17_-_84990360 Show fit	8.36	ENSMUST00000066175.10	Abcg5 Links Ensembl NCBI MGI UniProt Show fit	ATP binding cassette subfamily G member 5
chr12_-_103956176 Show fit	6.88	ENSMUST00000151709.3 ENSMUST00000176246.3 ENSMUST00000074693.13 ENSMUST00000120251.9	Serpina11 Links Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr9_-_103097022 Show fit	6.58	ENSMUST00000168142.8	Trf Links Ensembl NCBI MGI UniProt Show fit	transferrin
chr6_+_37507108 Show fit	6.22	ENSMUST00000040987.11	Akr1d1 Links Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member D1
chr4_+_115375461 Show fit	5.90	ENSMUST00000058785.10 ENSMUST00000094886.4	Cyp4a10 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 10
chr10_+_62897353 Show fit	5.82	ENSMUST00000178684.3 ENSMUST00000020266.15	Pbld1 Links Ensembl NCBI MGI UniProt Show fit	phenazine biosynthesis-like protein domain containing 1
chr1_+_160806241 Show fit	5.53	ENSMUST00000195760.2	Serpinc1 Links Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr17_+_84990541 Show fit	5.48	ENSMUST00000045714.15 ENSMUST00000171915.2	Abcg8 Links Ensembl NCBI MGI UniProt Show fit	ATP binding cassette subfamily G member 8
chr1_-_150341911 Show fit	5.06	ENSMUST00000162367.8 ENSMUST00000161611.8 ENSMUST00000161320.8 ENSMUST00000159035.2	Prg4 Links Ensembl NCBI MGI UniProt Show fit	proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr19_+_34268053 Show fit	4.99	ENSMUST00000025691.13	Fas Links Ensembl NCBI MGI UniProt Show fit	Fas (TNF receptor superfamily member 6)
chr7_-_19432933 Show fit	4.88	ENSMUST00000174355.8 ENSMUST00000172983.8 ENSMUST00000174710.2 ENSMUST00000003066.16 ENSMUST00000174064.9	Apoe Links Ensembl NCBI MGI UniProt Show fit	apolipoprotein E
chr2_+_43445333 Show fit	4.82	ENSMUST00000028223.9 ENSMUST00000112826.8	Kynu Links Ensembl NCBI MGI UniProt Show fit	kynureninase
chr5_-_145406533 Show fit	4.63	ENSMUST00000031633.5	Cyp3a16 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 16
chr11_+_98938137 Show fit	4.56	ENSMUST00000140772.2	Igfbp4 Links Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor binding protein 4
chr14_+_40826970 Show fit	4.56	ENSMUST00000225720.2	Mat1a Links Ensembl NCBI MGI UniProt Show fit	methionine adenosyltransferase I, alpha
chr1_+_160806194 Show fit	4.52	ENSMUST00000064725.11 ENSMUST00000191936.2	Serpinc1 Links Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr14_-_31362835 Show fit	4.46	ENSMUST00000167066.8 ENSMUST00000127204.9	Hacl1 Links Ensembl NCBI MGI UniProt Show fit	2-hydroxyacyl-CoA lyase 1
chr14_-_31362909 Show fit	4.43	ENSMUST00000022437.16	Hacl1 Links Ensembl NCBI MGI UniProt Show fit	2-hydroxyacyl-CoA lyase 1
chr19_+_34268071 Show fit	4.33	ENSMUST00000112472.4 ENSMUST00000235232.2	Fas Links Ensembl NCBI MGI UniProt Show fit	Fas (TNF receptor superfamily member 6)
chr1_-_139708906 Show fit	4.19	ENSMUST00000111986.8 ENSMUST00000027612.11 ENSMUST00000111989.9	Cfhr4 Links Ensembl NCBI MGI UniProt Show fit	complement factor H-related 4
chr1_-_139786421 Show fit	4.18	ENSMUST00000194186.6 ENSMUST00000094489.5 ENSMUST00000239380.2	Cfhr2 Links Ensembl NCBI MGI UniProt Show fit	complement factor H-related 2
chr7_-_14180496 Show fit	4.10	ENSMUST00000063509.11	Sult2a8 Links Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
chr8_-_25066313 Show fit	4.06	ENSMUST00000121992.2	Ido2 Links Ensembl NCBI MGI UniProt Show fit	indoleamine 2,3-dioxygenase 2
chr14_+_40827108 Show fit	3.87	ENSMUST00000224514.2	Mat1a Links Ensembl NCBI MGI UniProt Show fit	methionine adenosyltransferase I, alpha
chr6_+_70703409 Show fit	3.87	ENSMUST00000103410.3	Igkc Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa constant
chr5_+_135754568 Show fit	3.80	ENSMUST00000127096.2	Por Links Ensembl NCBI MGI UniProt Show fit	P450 (cytochrome) oxidoreductase
chr1_+_45350698 Show fit	3.67	ENSMUST00000087883.13	Col3a1 Links Ensembl NCBI MGI UniProt Show fit	collagen, type III, alpha 1
chr4_-_49506538 Show fit	3.62	ENSMUST00000043056.9	Baat Links Ensembl NCBI MGI UniProt Show fit	bile acid-Coenzyme A: amino acid N-acyltransferase
chr2_+_43445359 Show fit	3.61	ENSMUST00000050511.7	Kynu Links Ensembl NCBI MGI UniProt Show fit	kynureninase
chr4_+_115458172 Show fit	3.58	ENSMUST00000084342.6	Cyp4a32 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily a, polypeptide 32
chr4_+_140970161 Show fit	3.56	ENSMUST00000138096.8 ENSMUST00000006618.9 ENSMUST00000125392.8	Arhgef19 Links Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 19
chr5_-_145521533 Show fit	3.51	ENSMUST00000075837.8	Cyp3a41b Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 41B
chr8_-_4155758 Show fit	3.50	ENSMUST00000138439.2 ENSMUST00000145007.8	Cd209f Links Ensembl NCBI MGI UniProt Show fit	CD209f antigen
chr5_+_135703426 Show fit	3.43	ENSMUST00000153515.8	Por Links Ensembl NCBI MGI UniProt Show fit	P450 (cytochrome) oxidoreductase
chr17_-_7652863 Show fit	3.42	ENSMUST00000070059.5	Unc93a2 Links Ensembl NCBI MGI UniProt Show fit	unc-93 homolog A2
chr14_-_123150497 Show fit	3.42	ENSMUST00000162164.2 ENSMUST00000110679.9 ENSMUST00000161322.3 ENSMUST00000038075.12	Ggact Links Ensembl NCBI MGI UniProt Show fit	gamma-glutamylamine cyclotransferase
chr7_-_79497940 Show fit	3.39	ENSMUST00000107392.8	Anpep Links Ensembl NCBI MGI UniProt Show fit	alanyl (membrane) aminopeptidase
chr14_+_40827317 Show fit	3.37	ENSMUST00000047286.7	Mat1a Links Ensembl NCBI MGI UniProt Show fit	methionine adenosyltransferase I, alpha
chr7_-_14180576 Show fit	3.36	ENSMUST00000125941.3	Sult2a8 Links Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
chr1_-_162694076 Show fit	3.35	ENSMUST00000046049.14	Fmo1 Links Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 1
chr3_-_108443769 Show fit	3.32	ENSMUST00000048012.13 ENSMUST00000106625.10	Elapor1 Links Ensembl NCBI MGI UniProt Show fit	endosome-lysosome associated apoptosis and autophagy regulator 1
chr5_-_145656934 Show fit	3.29	ENSMUST00000094111.6	Cyp3a41a Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 41A
chr16_+_26400454 Show fit	3.15	ENSMUST00000096129.9 ENSMUST00000166294.9 ENSMUST00000174202.8 ENSMUST00000023156.13	Il1rap Links Ensembl NCBI MGI UniProt Show fit	interleukin 1 receptor accessory protein
chr7_+_43874854 Show fit	3.00	ENSMUST00000206144.2	Klk1 Links Ensembl NCBI MGI UniProt Show fit	kallikrein 1
chr7_+_43874752 Show fit	3.00	ENSMUST00000075162.5	Klk1 Links Ensembl NCBI MGI UniProt Show fit	kallikrein 1
chr1_+_92934050 Show fit	2.94	ENSMUST00000059676.5	Aqp12 Links Ensembl NCBI MGI UniProt Show fit	aquaporin 12
chr8_+_13076024 Show fit	2.87	ENSMUST00000033820.4	F7 Links Ensembl NCBI MGI UniProt Show fit	coagulation factor VII
chr4_-_115875055 Show fit	2.84	ENSMUST00000049095.6	Faah Links Ensembl NCBI MGI UniProt Show fit	fatty acid amide hydrolase
chr11_+_118319319 Show fit	2.79	ENSMUST00000017590.9	C1qtnf1 Links Ensembl NCBI MGI UniProt Show fit	C1q and tumor necrosis factor related protein 1
chr17_-_45997132 Show fit	2.78	ENSMUST00000113523.9	Tmem63b Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 63b
chr17_-_33166346 Show fit	2.75	ENSMUST00000139353.8	Cyp4f13 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily f, polypeptide 13
chr2_-_25390625 Show fit	2.73	ENSMUST00000040042.11	C8g Links Ensembl NCBI MGI UniProt Show fit	complement component 8, gamma polypeptide
chr11_+_120421496 Show fit	2.69	ENSMUST00000026119.8	Gcgr Links Ensembl NCBI MGI UniProt Show fit	glucagon receptor
chr6_+_72332449 Show fit	2.68	ENSMUST00000206064.2	Tmem150a Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 150A
chr17_-_45997046 Show fit	2.65	ENSMUST00000143907.3 ENSMUST00000127065.8	Tmem63b Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 63b
chr1_+_87998487 Show fit	2.62	ENSMUST00000073772.5	Ugt1a9 Links Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_+_72332423 Show fit	2.61	ENSMUST00000069695.9 ENSMUST00000132243.3	Tmem150a Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 150A
chr11_-_75313350 Show fit	2.52	ENSMUST00000125982.2 ENSMUST00000137103.8	Serpinf1 Links Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade F, member 1
chr1_-_170804116 Show fit	2.50	ENSMUST00000159969.8	Fcgr2b Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, low affinity IIb
chr17_-_45996899 Show fit	2.49	ENSMUST00000145873.8	Tmem63b Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 63b
chr1_+_164624200 Show fit	2.45	ENSMUST00000027861.6	Dpt Links Ensembl NCBI MGI UniProt Show fit	dermatopontin
chr11_-_75313412 Show fit	2.35	ENSMUST00000138661.8 ENSMUST00000000769.14	Serpinf1 Links Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade F, member 1
chr3_+_107137924 Show fit	2.33	ENSMUST00000179399.3	A630076J17Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA A630076J17 gene
chr9_-_36708599 Show fit	2.33	ENSMUST00000238932.2 ENSMUST00000115086.13	Ei24 Links Ensembl NCBI MGI UniProt Show fit	etoposide induced 2.4 mRNA
chr13_+_30520416 Show fit	2.25	ENSMUST00000222503.2 ENSMUST00000222370.2 ENSMUST00000066412.8 ENSMUST00000223201.2	Agtr1a Links Ensembl NCBI MGI UniProt Show fit	angiotensin II receptor, type 1a
chr9_+_43978290 Show fit	2.22	ENSMUST00000034508.14	Usp2 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 2
chr8_+_4184652 Show fit	2.12	ENSMUST00000130372.3	Cd209g Links Ensembl NCBI MGI UniProt Show fit	CD209g antigen
chr6_+_87405968 Show fit	2.11	ENSMUST00000032125.7	Bmp10 Links Ensembl NCBI MGI UniProt Show fit	bone morphogenetic protein 10
chr1_-_180021039 Show fit	2.11	ENSMUST00000160482.8 ENSMUST00000170472.8	Coq8a Links Ensembl NCBI MGI UniProt Show fit	coenzyme Q8A
chr16_-_22848153 Show fit	2.09	ENSMUST00000232459.2	Kng2 Links Ensembl NCBI MGI UniProt Show fit	kininogen 2
chr10_-_93375832 Show fit	2.08	ENSMUST00000016034.3	Amdhd1 Links Ensembl NCBI MGI UniProt Show fit	amidohydrolase domain containing 1
chr15_+_31568937 Show fit	2.01	ENSMUST00000162532.8 ENSMUST00000070918.14	Cmbl Links Ensembl NCBI MGI UniProt Show fit	carboxymethylenebutenolidase-like (Pseudomonas)
chr17_-_33166362 Show fit	1.97	ENSMUST00000234083.2 ENSMUST00000075253.13	Cyp4f13 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily f, polypeptide 13
chr15_-_96918203 Show fit	1.89	ENSMUST00000166223.2	Slc38a4 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 38, member 4
chr5_-_38649291 Show fit	1.89	ENSMUST00000129099.8	Slc2a9 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 9
chr7_-_79497922 Show fit	1.88	ENSMUST00000205502.2	Anpep Links Ensembl NCBI MGI UniProt Show fit	alanyl (membrane) aminopeptidase
chr11_-_109986804 Show fit	1.82	ENSMUST00000100287.9	Abca8a Links Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 8a
chr11_+_49500090 Show fit	1.81	ENSMUST00000020617.3	Flt4 Links Ensembl NCBI MGI UniProt Show fit	FMS-like tyrosine kinase 4
chr2_-_27137272 Show fit	1.80	ENSMUST00000102886.10 ENSMUST00000129975.2	Sardh Links Ensembl NCBI MGI UniProt Show fit	sarcosine dehydrogenase
chr12_+_29988035 Show fit	1.79	ENSMUST00000122328.8 ENSMUST00000118321.3	Pxdn Links Ensembl NCBI MGI UniProt Show fit	peroxidasin
chr14_+_31363004 Show fit	1.77	ENSMUST00000090147.7	Btd Links Ensembl NCBI MGI UniProt Show fit	biotinidase
chr17_-_13350642 Show fit	1.74	ENSMUST00000232960.2 ENSMUST00000084966.6 ENSMUST00000233405.2	Unc93a Links Ensembl NCBI MGI UniProt Show fit	unc-93 homolog A
chr17_-_84154196 Show fit	1.73	ENSMUST00000234214.2	Haao Links Ensembl NCBI MGI UniProt Show fit	3-hydroxyanthranilate 3,4-dioxygenase
chr14_+_40873399 Show fit	1.73	ENSMUST00000225792.2	Mbl1 Links Ensembl NCBI MGI UniProt Show fit	mannose-binding lectin (protein A) 1
chr11_-_109986763 Show fit	1.67	ENSMUST00000046223.14 ENSMUST00000106664.10 ENSMUST00000106662.2	Abca8a Links Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family A (ABC1), member 8a
chr4_-_44066960 Show fit	1.65	ENSMUST00000173234.8 ENSMUST00000173274.2	Gne Links Ensembl NCBI MGI UniProt Show fit	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_-_114952984 Show fit	1.65	ENSMUST00000062787.8	Cd300e Links Ensembl NCBI MGI UniProt Show fit	CD300E molecule
chr6_+_112250719 Show fit	1.64	ENSMUST00000032376.6	Lmcd1 Links Ensembl NCBI MGI UniProt Show fit	LIM and cysteine-rich domains 1
chr9_-_63306497 Show fit	1.61	ENSMUST00000168665.3	2300009A05Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2300009A05 gene
chr1_-_170755136 Show fit	1.60	ENSMUST00000046322.14 ENSMUST00000159171.2	Fcrla Links Ensembl NCBI MGI UniProt Show fit	Fc receptor-like A
chr9_+_108174052 Show fit	1.59	ENSMUST00000035230.7	Amt Links Ensembl NCBI MGI UniProt Show fit	aminomethyltransferase
chr6_-_6217126 Show fit	1.58	ENSMUST00000188414.4	Slc25a13 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr7_-_45679703 Show fit	1.57	ENSMUST00000002850.8	Abcc6 Links Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr16_-_56984137 Show fit	1.52	ENSMUST00000231733.2	Nit2 Links Ensembl NCBI MGI UniProt Show fit	nitrilase family, member 2
chr5_-_120610828 Show fit	1.52	ENSMUST00000052258.14 ENSMUST00000031594.13	Sdsl Links Ensembl NCBI MGI UniProt Show fit	serine dehydratase-like
chr6_+_91134358 Show fit	1.52	ENSMUST00000155007.2	Hdac11 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 11
chr6_+_91133755 Show fit	1.52	ENSMUST00000143621.8	Hdac11 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 11
chr6_+_72333209 Show fit	1.51	ENSMUST00000206531.2	Tmem150a Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 150A
chr6_-_35303057 Show fit	1.51	ENSMUST00000051176.9	Fam180a Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 180, member A
chr10_-_76562002 Show fit	1.50	ENSMUST00000001147.5	Col6a1 Links Ensembl NCBI MGI UniProt Show fit	collagen, type VI, alpha 1
chr2_-_150746574 Show fit	1.44	ENSMUST00000056149.15	Abhd12 Links Ensembl NCBI MGI UniProt Show fit	abhydrolase domain containing 12
chr11_+_118319029 Show fit	1.44	ENSMUST00000124861.2	C1qtnf1 Links Ensembl NCBI MGI UniProt Show fit	C1q and tumor necrosis factor related protein 1
chr12_-_58315949 Show fit	1.44	ENSMUST00000062254.4	Clec14a Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 14, member a
chr12_-_101785307 Show fit	1.44	ENSMUST00000021603.9	Fbln5 Links Ensembl NCBI MGI UniProt Show fit	fibulin 5
chr5_+_137348363 Show fit	1.43	ENSMUST00000061244.15	Ephb4 Links Ensembl NCBI MGI UniProt Show fit	Eph receptor B4
chr7_-_98010478 Show fit	1.43	ENSMUST00000094161.11 ENSMUST00000164726.8 ENSMUST00000206414.2 ENSMUST00000167405.3	Tsku Links Ensembl NCBI MGI UniProt Show fit	tsukushi, small leucine rich proteoglycan
chr4_-_130172998 Show fit	1.42	ENSMUST00000120126.9	Serinc2 Links Ensembl NCBI MGI UniProt Show fit	serine incorporator 2
chr9_+_65537834 Show fit	1.41	ENSMUST00000055844.10	Rbpms2 Links Ensembl NCBI MGI UniProt Show fit	RNA binding protein with multiple splicing 2
chr15_+_31225302 Show fit	1.41	ENSMUST00000186425.7	Dap Links Ensembl NCBI MGI UniProt Show fit	death-associated protein
chr4_-_44073016 Show fit	1.39	ENSMUST00000128439.8 ENSMUST00000140724.3	Gne Links Ensembl NCBI MGI UniProt Show fit	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr6_+_91133647 Show fit	1.38	ENSMUST00000041736.11	Hdac11 Links Ensembl NCBI MGI UniProt Show fit	histone deacetylase 11
chr2_-_168576155 Show fit	1.37	ENSMUST00000109175.9	Atp9a Links Ensembl NCBI MGI UniProt Show fit	ATPase, class II, type 9A
chr13_+_58954447 Show fit	1.37	ENSMUST00000224259.2	Ntrk2 Links Ensembl NCBI MGI UniProt Show fit	neurotrophic tyrosine kinase, receptor, type 2
chr1_-_170755109 Show fit	1.35	ENSMUST00000162136.2 ENSMUST00000162887.2	Fcrla Links Ensembl NCBI MGI UniProt Show fit	Fc receptor-like A
chr9_-_58462720 Show fit	1.34	ENSMUST00000165365.3	Cd276 Links Ensembl NCBI MGI UniProt Show fit	CD276 antigen
chr11_-_68848271 Show fit	1.31	ENSMUST00000108671.2	Arhgef15 Links Ensembl NCBI MGI UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 15
chr7_-_63588610 Show fit	1.31	ENSMUST00000063694.10	Klf13 Links Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 13
chr18_+_45402018 Show fit	1.29	ENSMUST00000183850.8 ENSMUST00000066890.14	Kcnn2 Links Ensembl NCBI MGI UniProt Show fit	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr18_-_12995261 Show fit	1.27	ENSMUST00000234427.2	Osbpl1a Links Ensembl NCBI MGI UniProt Show fit	oxysterol binding protein-like 1A
chr17_+_73433422 Show fit	1.24	ENSMUST00000232703.2	Lclat1 Links Ensembl NCBI MGI UniProt Show fit	lysocardiolipin acyltransferase 1
chr16_+_22926504 Show fit	1.23	ENSMUST00000187168.7 ENSMUST00000232287.2 ENSMUST00000077605.12	Eif4a2 Links Ensembl NCBI MGI UniProt Show fit	eukaryotic translation initiation factor 4A2
chr17_+_45997248 Show fit	1.23	ENSMUST00000024734.8	Mrpl14 Links Ensembl NCBI MGI UniProt Show fit	mitochondrial ribosomal protein L14
chr7_-_126497421 Show fit	1.22	ENSMUST00000121532.8 ENSMUST00000032926.12	Tmem219 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 219
chr1_-_14826208 Show fit	1.21	ENSMUST00000027062.7	Msc Links Ensembl NCBI MGI UniProt Show fit	musculin
chr7_+_126549692 Show fit	1.20	ENSMUST00000106335.8 ENSMUST00000146017.3	Sez6l2 Links Ensembl NCBI MGI UniProt Show fit	seizure related 6 homolog like 2
chr4_+_43414696 Show fit	1.17	ENSMUST00000131668.3	Rusc2 Links Ensembl NCBI MGI UniProt Show fit	RUN and SH3 domain containing 2
chr11_-_53313950 Show fit	1.17	ENSMUST00000036045.6	Leap2 Links Ensembl NCBI MGI UniProt Show fit	liver-expressed antimicrobial peptide 2
chr8_+_56747613 Show fit	1.15	ENSMUST00000034026.10	Hpgd Links Ensembl NCBI MGI UniProt Show fit	hydroxyprostaglandin dehydrogenase 15 (NAD)
chr11_-_69553451 Show fit	1.15	ENSMUST00000018905.12	Mpdu1 Links Ensembl NCBI MGI UniProt Show fit	mannose-P-dolichol utilization defect 1
chr16_-_94327689 Show fit	1.15	ENSMUST00000023615.7	Vps26c Links Ensembl NCBI MGI UniProt Show fit	VPS26 endosomal protein sorting factor C
chr4_-_130169335 Show fit	1.14	ENSMUST00000154846.2 ENSMUST00000105996.8	Serinc2 Links Ensembl NCBI MGI UniProt Show fit	serine incorporator 2
chr6_+_68026941 Show fit	1.13	ENSMUST00000103316.2	Igkv9-120 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 9-120
chr10_-_95159933 Show fit	1.12	ENSMUST00000053594.7	Cradd Links Ensembl NCBI MGI UniProt Show fit	CASP2 and RIPK1 domain containing adaptor with death domain
chr13_+_43938251 Show fit	1.11	ENSMUST00000015540.4	Cd83 Links Ensembl NCBI MGI UniProt Show fit	CD83 antigen
chr4_-_107889267 Show fit	1.10	ENSMUST00000106709.9	Podn Links Ensembl NCBI MGI UniProt Show fit	podocan
chr6_+_78382131 Show fit	1.10	ENSMUST00000023906.4	Reg2 Links Ensembl NCBI MGI UniProt Show fit	regenerating islet-derived 2
chr2_+_84880776 Show fit	1.10	ENSMUST00000111605.9	Tnks1bp1 Links Ensembl NCBI MGI UniProt Show fit	tankyrase 1 binding protein 1
chr3_-_88460166 Show fit	1.09	ENSMUST00000119002.2 ENSMUST00000029698.15	Lamtor2 Links Ensembl NCBI MGI UniProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chrX_-_7884688 Show fit	1.08	ENSMUST00000033503.3	Glod5 Links Ensembl NCBI MGI UniProt Show fit	glyoxalase domain containing 5
chr8_-_37200051 Show fit	1.08	ENSMUST00000098826.10	Dlc1 Links Ensembl NCBI MGI UniProt Show fit	deleted in liver cancer 1
chr9_+_65536892 Show fit	1.08	ENSMUST00000169003.8	Rbpms2 Links Ensembl NCBI MGI UniProt Show fit	RNA binding protein with multiple splicing 2
chr7_+_107166925 Show fit	1.07	ENSMUST00000239087.2	Olfml1 Links Ensembl NCBI MGI UniProt Show fit	olfactomedin-like 1
chr14_-_20231871 Show fit	1.06	ENSMUST00000024011.10	Kcnk5 Links Ensembl NCBI MGI UniProt Show fit	potassium channel, subfamily K, member 5
chr15_-_98660873 Show fit	1.04	ENSMUST00000156572.3	Arf3 Links Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor 3
chr9_+_43978369 Show fit	1.04	ENSMUST00000177054.8	Usp2 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 2
chr2_+_127267069 Show fit	1.02	ENSMUST00000062211.4	Gpat2 Links Ensembl NCBI MGI UniProt Show fit	glycerol-3-phosphate acyltransferase 2, mitochondrial
chr2_+_10085411 Show fit	1.02	ENSMUST00000042512.8	Kin Links Ensembl NCBI MGI UniProt Show fit	Kin17 DNA and RNA binding protein
chr5_+_87148697 Show fit	1.01	ENSMUST00000031186.9	Ugt2b35 Links Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B35
chr3_-_88366159 Show fit	1.01	ENSMUST00000147200.8 ENSMUST00000169222.8	Sema4a Links Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_-_98010534 Show fit	1.00	ENSMUST00000165257.8	Tsku Links Ensembl NCBI MGI UniProt Show fit	tsukushi, small leucine rich proteoglycan
chr4_-_107889136 Show fit	1.00	ENSMUST00000106708.8	Podn Links Ensembl NCBI MGI UniProt Show fit	podocan
chr5_-_92475927 Show fit	0.99	ENSMUST00000113093.5	Cxcl9 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) ligand 9
chr12_+_88327607 Show fit	0.97	ENSMUST00000166940.3	Adck1 Links Ensembl NCBI MGI UniProt Show fit	aarF domain containing kinase 1
chr5_-_108596960 Show fit	0.95	ENSMUST00000031455.5	Mfsd7a Links Ensembl NCBI MGI UniProt Show fit	major facilitator superfamily domain containing 7A
chr11_+_101221431 Show fit	0.94	ENSMUST00000103105.10	Aoc3 Links Ensembl NCBI MGI UniProt Show fit	amine oxidase, copper containing 3
chr11_+_95733489 Show fit	0.94	ENSMUST00000100532.10 ENSMUST00000036088.11	Gngt2 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_-_69553390 Show fit	0.94	ENSMUST00000129224.8 ENSMUST00000155200.8	Mpdu1 Links Ensembl NCBI MGI UniProt Show fit	mannose-P-dolichol utilization defect 1
chr11_+_80044931 Show fit	0.93	ENSMUST00000021050.14	Adap2 Links Ensembl NCBI MGI UniProt Show fit	ArfGAP with dual PH domains 2
chr14_-_63746541 Show fit	0.93	ENSMUST00000022522.15	Tdh Links Ensembl NCBI MGI UniProt Show fit	L-threonine dehydrogenase
chr2_+_144435974 Show fit	0.92	ENSMUST00000136628.2	Smim26 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 26
chr11_-_106641454 Show fit	0.92	ENSMUST00000068021.9	Pecam1 Links Ensembl NCBI MGI UniProt Show fit	platelet/endothelial cell adhesion molecule 1
chr7_-_28078671 Show fit	0.90	ENSMUST00000209061.2	Zfp36 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 36
chr11_+_87473027 Show fit	0.90	ENSMUST00000133202.3	Septin4 Links Ensembl NCBI MGI UniProt Show fit	septin 4
chr15_-_103248512 Show fit	0.89	ENSMUST00000168828.3	Zfp385a Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 385A
chr18_+_11972277 Show fit	0.89	ENSMUST00000171109.9 ENSMUST00000046948.10	Cables1 Links Ensembl NCBI MGI UniProt Show fit	CDK5 and Abl enzyme substrate 1
chr4_-_149569614 Show fit	0.89	ENSMUST00000126896.2 ENSMUST00000105693.2 ENSMUST00000030845.13	Nmnat1 Links Ensembl NCBI MGI UniProt Show fit	nicotinamide nucleotide adenylyltransferase 1
chr9_-_116004386 Show fit	0.88	ENSMUST00000035014.8	Tgfbr2 Links Ensembl NCBI MGI UniProt Show fit	transforming growth factor, beta receptor II
chr7_-_97387429 Show fit	0.88	ENSMUST00000206389.2	Aqp11 Links Ensembl NCBI MGI UniProt Show fit	aquaporin 11
chr17_+_11059309 Show fit	0.87	ENSMUST00000233706.2	Prkn Links Ensembl NCBI MGI UniProt Show fit	parkin RBR E3 ubiquitin protein ligase
chr18_-_12995395 Show fit	0.86	ENSMUST00000121888.8	Osbpl1a Links Ensembl NCBI MGI UniProt Show fit	oxysterol binding protein-like 1A
chr12_+_88327391 Show fit	0.85	ENSMUST00000222695.2	Adck1 Links Ensembl NCBI MGI UniProt Show fit	aarF domain containing kinase 1
chr13_+_74787952 Show fit	0.84	ENSMUST00000221822.2 ENSMUST00000221526.2	Erap1 Links Ensembl NCBI MGI UniProt Show fit	endoplasmic reticulum aminopeptidase 1
chr2_+_68966125 Show fit	0.84	ENSMUST00000041865.8	Nostrin Links Ensembl NCBI MGI UniProt Show fit	nitric oxide synthase trafficker
chr6_+_90443293 Show fit	0.84	ENSMUST00000203607.2	Klf15 Links Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 15
chr7_+_126549859 Show fit	0.84	ENSMUST00000106333.8	Sez6l2 Links Ensembl NCBI MGI UniProt Show fit	seizure related 6 homolog like 2
chr17_-_34000804 Show fit	0.83	ENSMUST00000002360.17	Angptl4 Links Ensembl NCBI MGI UniProt Show fit	angiopoietin-like 4
chr3_+_121220146 Show fit	0.83	ENSMUST00000029773.13	Cnn3 Links Ensembl NCBI MGI UniProt Show fit	calponin 3, acidic
chr10_+_59715439 Show fit	0.83	ENSMUST00000142819.8 ENSMUST00000020309.7	Dnajb12 Links Ensembl NCBI MGI UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B12
chr3_-_88366351 Show fit	0.83	ENSMUST00000165898.8 ENSMUST00000127436.8	Sema4a Links Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_-_66826661 Show fit	0.82	ENSMUST00000167962.2 ENSMUST00000070538.12	Rab12 Links Ensembl NCBI MGI UniProt Show fit	RAB12, member RAS oncogene family
chr5_-_36987917 Show fit	0.82	ENSMUST00000031002.10	Man2b2 Links Ensembl NCBI MGI UniProt Show fit	mannosidase 2, alpha B2
chr17_-_36290129 Show fit	0.81	ENSMUST00000165613.9 ENSMUST00000173872.8	Prr3 Links Ensembl NCBI MGI UniProt Show fit	proline-rich polypeptide 3
chr12_+_88327305 Show fit	0.81	ENSMUST00000101165.9	Adck1 Links Ensembl NCBI MGI UniProt Show fit	aarF domain containing kinase 1
chr7_+_3696601 Show fit	0.81	ENSMUST00000123088.8 ENSMUST00000205287.2 ENSMUST00000038521.14 ENSMUST00000108629.8 ENSMUST00000142713.2	Tsen34 Links Ensembl NCBI MGI UniProt Show fit	tRNA splicing endonuclease subunit 34
chr7_-_44711075 Show fit	0.81	ENSMUST00000007981.9 ENSMUST00000210500.2 ENSMUST00000210493.2	Prrg2 Links Ensembl NCBI MGI UniProt Show fit	proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr16_-_10810964 Show fit	0.81	ENSMUST00000023143.14	Litaf Links Ensembl NCBI MGI UniProt Show fit	LPS-induced TN factor
chr4_+_155924181 Show fit	0.80	ENSMUST00000030947.4	Mxra8 Links Ensembl NCBI MGI UniProt Show fit	matrix-remodelling associated 8
chr2_-_65069383 Show fit	0.80	ENSMUST00000155916.8 ENSMUST00000156643.2	Cobll1 Links Ensembl NCBI MGI UniProt Show fit	Cobl-like 1
chr18_+_84869456 Show fit	0.78	ENSMUST00000160180.9	Cyb5a Links Ensembl NCBI MGI UniProt Show fit	cytochrome b5 type A (microsomal)
chrX_-_161426542 Show fit	0.78	ENSMUST00000101102.2	Reps2 Links Ensembl NCBI MGI UniProt Show fit	RALBP1 associated Eps domain containing protein 2
chr3_-_96812610 Show fit	0.78	ENSMUST00000029738.14	Gpr89 Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 89
chr10_+_53213763 Show fit	0.78	ENSMUST00000219491.2 ENSMUST00000163319.9 ENSMUST00000220197.2 ENSMUST00000046221.8 ENSMUST00000218468.2 ENSMUST00000219921.2	Pln Links Ensembl NCBI MGI UniProt Show fit	phospholamban

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.8	GO:0009087	methionine catabolic process(GO:0009087)
2.9	8.7	GO:0031104	dendrite regeneration(GO:0031104)
2.8	8.4	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
2.3	13.8	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
2.1	6.2	GO:0030573	bile acid catabolic process(GO:0030573)
1.9	5.8	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
1.8	7.2	GO:0046210	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
1.6	4.9	GO:1903000	regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
1.3	8.9	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
1.3	10.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
1.3	7.5	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.8	6.6	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.8	1.6	GO:0002514	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.7	2.2	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.7	3.7	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6	2.5	GO:0002884	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) negative regulation of hypersensitivity(GO:0002884) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.6	1.8	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.6	5.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.5	1.6	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5	4.1	GO:0019441	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.5	2.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.5	1.4	GO:0046462	monoacylglycerol metabolic process(GO:0046462)
0.5	2.9	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.4	3.1	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4	2.1	GO:0006548	histidine catabolic process(GO:0006548)
0.4	4.9	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4	1.6	GO:0048388	endosomal lumen acidification(GO:0048388)
0.4	0.4	GO:1901630	negative regulation of presynaptic membrane organization(GO:1901630)
0.4	4.0	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4	2.1	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3	16.4	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.3	1.7	GO:0046874	quinolinate metabolic process(GO:0046874)
0.3	2.7	GO:0033762	response to glucagon(GO:0033762)
0.3	2.0	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.3	1.3	GO:2000297	negative regulation of synapse maturation(GO:2000297)
0.3	1.6	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.3	0.9	GO:0006566	threonine metabolic process(GO:0006566)
0.3	0.9	GO:0090673	endothelial cell-matrix adhesion(GO:0090673)
0.3	1.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.3	3.6	GO:0006544	glycine metabolic process(GO:0006544)
0.3	0.9	GO:1904582	regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.3	5.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3	3.0	GO:0072602	interleukin-4 secretion(GO:0072602)
0.3	5.3	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.2	0.5	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.2	0.7	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2	2.1	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2	2.3	GO:0071494	cellular response to UV-C(GO:0071494)
0.2	0.7	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2	1.1	GO:0032917	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2	0.9	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.2	2.6	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2	1.5	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.2	33.8	GO:0007586	digestion(GO:0007586)
0.2	3.7	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.2	0.6	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2	2.5	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2	3.3	GO:0070995	NADPH oxidation(GO:0070995)
0.2	1.0	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2	6.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.2	2.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.2	0.8	GO:0060857	establishment of glial blood-brain barrier(GO:0060857)
0.2	1.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.2	0.5	GO:0090076	maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.2	0.6	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2	4.6	GO:0006691	leukotriene metabolic process(GO:0006691)
0.1	3.4	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.1	1.4	GO:2000121	regulation of removal of superoxide radicals(GO:2000121)
0.1	0.8	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.3	GO:0002760	positive regulation of antimicrobial humoral response(GO:0002760) negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.1	1.7	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	2.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	3.3	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.1	0.5	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	1.8	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.1	1.7	GO:0007567	parturition(GO:0007567)
0.1	0.7	GO:0006172	ADP biosynthetic process(GO:0006172)
0.1	0.9	GO:0035902	response to immobilization stress(GO:0035902)
0.1	0.9	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.7	GO:0000042	protein targeting to Golgi(GO:0000042)
0.1	0.6	GO:0071718	sodium-independent icosanoid transport(GO:0071718)
0.1	0.2	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1	0.3	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273) negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1	1.8	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	1.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	2.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.1	0.6	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1	0.5	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1	1.9	GO:0046415	urate metabolic process(GO:0046415)
0.1	2.1	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.1	0.3	GO:2000077	transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of establishment of Sertoli cell barrier(GO:1904446) negative regulation of type B pancreatic cell development(GO:2000077)
0.1	1.6	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	0.3	GO:0098749	cerebellar neuron development(GO:0098749)
0.1	1.6	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.1	4.4	GO:0014003	oligodendrocyte development(GO:0014003)
0.1	1.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.4	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	0.7	GO:0061709	reticulophagy(GO:0061709)
0.1	0.8	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1	0.2	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.1	0.8	GO:0006013	mannose metabolic process(GO:0006013)
0.1	1.5	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	1.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.6	GO:0009407	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1	0.6	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.1	1.8	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	0.3	GO:0070173	regulation of enamel mineralization(GO:0070173)
0.1	0.4	GO:0000255	allantoin metabolic process(GO:0000255)
0.1	0.6	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.3	GO:0070829	heterochromatin maintenance(GO:0070829)
0.1	3.1	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	0.3	GO:2000657	regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1	0.2	GO:0015882	L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1	0.4	GO:0009405	pathogenesis(GO:0009405)
0.1	1.8	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.1	0.4	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.2	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1	0.8	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	1.5	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	1.5	GO:0006767	water-soluble vitamin metabolic process(GO:0006767)
0.1	0.4	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
0.1	1.0	GO:0010818	T cell chemotaxis(GO:0010818)
0.1	2.4	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0	0.4	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.0	0.3	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.1	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.0	2.6	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.7	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.8	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	1.4	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.7	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	1.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.1	GO:1902623	negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of monocyte chemotaxis(GO:0090027) negative regulation of neutrophil migration(GO:1902623)
0.0	0.1	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0	0.4	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	1.4	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.6	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.7	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.8	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.6	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0	0.2	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.0	0.8	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	1.4	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.8	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.6	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.5	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.0	0.7	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.5	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:1904124	negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0	0.2	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	1.1	GO:0032008	activation of MAPKK activity(GO:0000186) positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.5	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	2.9	GO:0009062	fatty acid catabolic process(GO:0009062)
0.0	0.1	GO:0098942	cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by soluble gas(GO:0099543)
0.0	2.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.5	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	1.2	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.2	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.3	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.0	0.8	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.1	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0	0.6	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.8	GO:0051452	intracellular pH reduction(GO:0051452)
0.0	0.7	GO:0010644	cell communication by electrical coupling(GO:0010644)
0.0	0.5	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	2.4	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	4.3	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.2	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0	0.2	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.2	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.8	GO:0016239	endosome to lysosome transport(GO:0008333) positive regulation of macroautophagy(GO:0016239)
0.0	0.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0015675	nickel cation transport(GO:0015675)
0.0	0.4	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0	0.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.0	GO:0070340	detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0	0.3	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.1	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.5	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.4	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	2.3	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.3	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	10.8	GO:0055114	oxidation-reduction process(GO:0055114)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	9.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
1.0	4.9	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.9	13.8	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.6	6.6	GO:0097433	dense body(GO:0097433)
0.5	7.5	GO:0031983	vesicle lumen(GO:0031983)
0.3	0.9	GO:0098842	postsynaptic early endosome(GO:0098842)
0.3	2.7	GO:0005579	membrane attack complex(GO:0005579)
0.3	1.4	GO:0071953	elastic fiber(GO:0071953)
0.3	3.7	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3	0.8	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.2	0.7	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.2	3.2	GO:0043203	axon hillock(GO:0043203)
0.2	1.4	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1	1.1	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.6	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	0.7	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.9	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	2.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	11.2	GO:0016363	nuclear matrix(GO:0016363)
0.1	0.9	GO:0060091	kinocilium(GO:0060091)
0.1	7.2	GO:0005581	collagen trimer(GO:0005581)
0.1	0.7	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	19.1	GO:0072562	blood microparticle(GO:0072562)
0.1	0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.1	0.5	GO:1990246	uniplex complex(GO:1990246)
0.1	0.5	GO:0005827	polar microtubule(GO:0005827)
0.1	0.5	GO:0031673	H zone(GO:0031673)
0.1	0.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	1.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.7	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	32.1	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0072534	perineuronal net(GO:0072534)
0.0	2.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	2.5	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	10.9	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.2	GO:1990584	cardiac Troponin complex(GO:1990584)
0.0	3.2	GO:0005901	caveola(GO:0005901)
0.0	7.9	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.2	GO:0097441	basilar dendrite(GO:0097441)
0.0	3.7	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	1.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.8	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	10.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.6	GO:0097225	sperm midpiece(GO:0097225)
0.0	3.7	GO:0055037	recycling endosome(GO:0055037)
0.0	0.5	GO:0031985	Golgi cisterna(GO:0031985)
0.0	12.6	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.2	GO:0070847	core mediator complex(GO:0070847)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	1.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	30.3	GO:0005615	extracellular space(GO:0005615)
0.0	0.3	GO:0042555	MCM complex(GO:0042555)
0.0	0.5	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	18.6	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	1.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	11.8	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
2.8	8.5	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
2.8	19.3	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
2.3	9.3	GO:0043120	tumor necrosis factor binding(GO:0043120)
2.1	8.4	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.8	7.2	GO:0008941	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
1.6	4.9	GO:0046911	metal chelating activity(GO:0046911)
1.4	11.4	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
1.4	4.1	GO:0033754	indoleamine 2,3-dioxygenase activity(GO:0033754)
1.2	6.2	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.9	6.6	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.9	2.7	GO:0004967	glucagon receptor activity(GO:0004967)
0.8	3.1	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.7	2.2	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.7	8.9	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.7	18.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.6	3.0	GO:0008761	UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.6	1.8	GO:0008480	sarcosine dehydrogenase activity(GO:0008480)
0.6	3.4	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.5	1.6	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.5	1.5	GO:0004794	L-threonine ammonia-lyase activity(GO:0004794)
0.5	13.8	GO:0017127	cholesterol transporter activity(GO:0017127)
0.5	4.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.4	1.8	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3	2.0	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3	1.6	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.3	0.9	GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3	2.1	GO:0019770	IgG receptor activity(GO:0019770)
0.3	5.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	3.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3	1.1	GO:0019809	spermidine binding(GO:0019809)
0.3	4.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	2.3	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.3	3.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2	0.7	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2	2.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2	60.5	GO:0008236	serine-type peptidase activity(GO:0008236)
0.2	5.2	GO:0005537	mannose binding(GO:0005537)
0.2	2.1	GO:0031433	telethonin binding(GO:0031433)
0.2	3.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.2	0.7	GO:0008802	betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2	5.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	1.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	1.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.2	3.9	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2	2.7	GO:0019841	retinol binding(GO:0019841)
0.2	1.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.2	1.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.2	0.9	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2	22.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.3	GO:0005119	smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1	1.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.4	GO:0004373	glycogen (starch) synthase activity(GO:0004373)
0.1	3.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.4	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.4	GO:0001847	opsonin receptor activity(GO:0001847)
0.1	1.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.5	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	2.5	GO:0070513	death domain binding(GO:0070513)
0.1	0.6	GO:0001595	angiotensin receptor activity(GO:0001595)
0.1	1.5	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.3	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	1.9	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.7	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1	0.7	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1	2.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.6	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.6	GO:0050610	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1	0.3	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.1	1.6	GO:0015250	water channel activity(GO:0015250)
0.1	0.7	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	3.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.8	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1	0.6	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	3.9	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	1.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	1.7	GO:0019825	oxygen binding(GO:0019825)
0.1	1.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.9	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.0	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.9	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	6.3	GO:0005518	collagen binding(GO:0005518)
0.1	0.2	GO:0070890	L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1	1.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	1.8	GO:0043274	phospholipase binding(GO:0043274)
0.1	1.0	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.1	0.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.3	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	1.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.7	GO:0042731	PH domain binding(GO:0042731)
0.1	0.4	GO:0071617	lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.7	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.8	GO:0015923	alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0	1.1	GO:0031005	filamin binding(GO:0031005)
0.0	6.8	GO:0043492	ATPase activity, coupled to movement of substances(GO:0043492)
0.0	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	2.1	GO:0043531	ADP binding(GO:0043531)
0.0	2.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	2.1	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.2	GO:0031013	troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0	0.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.6	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.6	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0001962	alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.5	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	1.0	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.3	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	3.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	2.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.4	GO:0016594	glycine binding(GO:0016594)
0.0	1.2	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0015099	nickel cation transmembrane transporter activity(GO:0015099)
0.0	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	1.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.8	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	2.2	GO:0016853	isomerase activity(GO:0016853)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707) MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	1.1	GO:0032947	protein complex scaffold(GO:0032947)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	1.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	11.7	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	7.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	4.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	30.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.8	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	5.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.5	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	2.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	2.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	9.3	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	1.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	3.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	5.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	2.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.9	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	1.7	PID SHP2 PATHWAY	SHP2 signaling
0.0	5.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	1.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	14.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.8	23.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.6	8.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.6	2.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.6	13.8	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.5	9.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.5	7.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.4	9.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.4	8.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.3	11.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.3	4.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	2.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	3.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	2.0	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.2	1.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	8.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1	1.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.1	2.9	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	5.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.4	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	1.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	3.5	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	1.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	3.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	2.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	3.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	2.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.9	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.9	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	2.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.8	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	2.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP