Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Zbtb49

Z-value: 0.73

Motif logo

logo of

Transcription factors associated with Zbtb49

Gene Symbol Gene ID Gene Info
Zbtb49
ENSMUSG00000029127.16 zinc finger and BTB domain containing 49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb49mm39_v1_chr5_-_38377746_38377801-0.554.7e-04Click!

Activity profile of Zbtb49 motif

Sorted Z-values of Zbtb49 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_39637489 7.32 ENSMUST00000067328.7
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr15_-_34495329 6.59 ENSMUST00000022946.6
Rida
reactive intermediate imine deaminase A homolog
chr17_+_24955613 5.96 ENSMUST00000115262.9
Msrb1
methionine sulfoxide reductase B1
chr17_+_24955647 5.82 ENSMUST00000101800.7
Msrb1
methionine sulfoxide reductase B1
chr18_-_62044871 5.00 ENSMUST00000166783.3
ENSMUST00000049378.15
Ablim3
actin binding LIM protein family, member 3
chr6_+_71176811 4.19 ENSMUST00000067492.8
Fabp1
fatty acid binding protein 1, liver
chr7_-_34914675 3.18 ENSMUST00000118444.3
ENSMUST00000122409.8
Lrp3
low density lipoprotein receptor-related protein 3
chr7_-_139734637 2.21 ENSMUST00000059241.8
Sprn
shadow of prion protein
chr15_-_100320872 1.50 ENSMUST00000138843.8
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr5_+_108777855 1.34 ENSMUST00000078323.13
ENSMUST00000120327.3
Tmem175
transmembrane protein 175
chr5_+_108777636 1.32 ENSMUST00000146207.6
ENSMUST00000063272.13
Tmem175
transmembrane protein 175
chr15_-_3333003 1.19 ENSMUST00000165386.2
Ccdc152
coiled-coil domain containing 152
chr8_+_105727456 1.06 ENSMUST00000172032.4
Ces2h
carboxylesterase 2H
chr15_+_100321074 1.06 ENSMUST00000148928.2
Gm5475
predicted gene 5475
chr2_-_80411578 0.89 ENSMUST00000028386.12
Nckap1
NCK-associated protein 1
chr2_-_80411724 0.89 ENSMUST00000111760.3
Nckap1
NCK-associated protein 1
chr7_-_97848688 0.80 ENSMUST00000098278.4
B3gnt6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr3_-_52924616 0.76 ENSMUST00000193432.6
ENSMUST00000195183.2
ENSMUST00000036665.10
Cog6
component of oligomeric golgi complex 6
chr8_-_106706035 0.70 ENSMUST00000034371.9
Dpep3
dipeptidase 3
chr14_-_68893253 0.68 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
Adam28
a disintegrin and metallopeptidase domain 28
chr9_+_45341589 0.67 ENSMUST00000239471.2
ENSMUST00000034592.11
ENSMUST00000239429.2
Dscaml1
DS cell adhesion molecule like 1
chr9_+_40180726 0.56 ENSMUST00000171835.9
Scn3b
sodium channel, voltage-gated, type III, beta
chr5_-_108777578 0.55 ENSMUST00000046603.15
Gak
cyclin G associated kinase
chr1_+_32211792 0.53 ENSMUST00000027226.12
ENSMUST00000189878.2
ENSMUST00000188257.7
ENSMUST00000185666.2
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr12_+_89779178 0.47 ENSMUST00000238943.2
Nrxn3
neurexin III
chr3_+_154302989 0.47 ENSMUST00000140644.8
ENSMUST00000144764.8
ENSMUST00000155232.2
Cryz
crystallin, zeta
chr8_-_106723026 0.45 ENSMUST00000227363.2
ENSMUST00000081998.13
Dpep2
dipeptidase 2
chr12_+_89779237 0.41 ENSMUST00000110133.9
ENSMUST00000110130.4
Nrxn3
neurexin III
chr14_-_122703089 0.27 ENSMUST00000039118.7
Zic5
zinc finger protein of the cerebellum 5
chr2_+_131048998 0.26 ENSMUST00000153097.3
Ap5s1
adaptor-related protein 5 complex, sigma 1 subunit
chr5_+_35971697 0.25 ENSMUST00000130233.8
Ablim2
actin-binding LIM protein 2
chrX_+_20714782 0.22 ENSMUST00000001155.11
ENSMUST00000122312.8
ENSMUST00000120356.8
ENSMUST00000122850.2
Araf
Araf proto-oncogene, serine/threonine kinase
chr17_-_89099404 0.22 ENSMUST00000024916.7
Lhcgr
luteinizing hormone/choriogonadotropin receptor
chr14_+_53279810 0.19 ENSMUST00000198439.5
ENSMUST00000103605.3
Trav8d-2
T cell receptor alpha variable 8D-2
chr13_+_19445054 0.15 ENSMUST00000164407.2
ENSMUST00000198163.2
Trgc3
T cell receptor gamma, constant 3
chr2_-_167082505 0.05 ENSMUST00000088041.11
ENSMUST00000018113.8
Ptgis
prostaglandin I2 (prostacyclin) synthase

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb49

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.8 GO:0030091 protein repair(GO:0030091)
0.3 4.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 1.8 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 2.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 7.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 0.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 5.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 6.6 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 1.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0007140 male meiosis(GO:0007140)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0045179 apical cortex(GO:0045179)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.0 5.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 6.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 12.0 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 11.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.7 6.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.5 4.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 7.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 2.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 4.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins