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GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb6

Z-value: 0.73

Motif logo

Transcription factors associated with Zbtb6

Gene Symbol Gene ID Gene Info
ENSMUSG00000066798.4 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb6mm39_v1_chr2_-_37333109_37333210-0.124.7e-01Click!

Activity profile of Zbtb6 motif

Sorted Z-values of Zbtb6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_87724533 4.96 ENSMUST00000126353.8
ENSMUST00000149357.8
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr17_+_37180437 4.21 ENSMUST00000060524.11
tripartite motif-containing 10
chr6_-_60806810 3.61 ENSMUST00000163779.8
synuclein, alpha
chr4_-_87724512 3.60 ENSMUST00000148059.2
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr11_-_102787950 3.54 ENSMUST00000067444.10
glial fibrillary acidic protein
chr6_+_86005729 3.32 ENSMUST00000203366.3
adducin 2 (beta)
chr6_+_86005663 2.99 ENSMUST00000204059.3
adducin 2 (beta)
chr8_-_86091970 2.93 ENSMUST00000121972.8
myosin light chain kinase 3
chr8_-_86091946 2.92 ENSMUST00000034133.14
myosin light chain kinase 3
chr3_-_100396635 2.71 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr4_+_117692583 2.20 ENSMUST00000169885.8
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr9_-_21671571 2.17 ENSMUST00000217382.2
ENSMUST00000214149.2
ENSMUST00000098942.6
ENSMUST00000216057.2
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr9_+_107468146 2.14 ENSMUST00000195746.2
interferon-related developmental regulator 2
chr1_+_134110142 2.08 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr11_-_102787972 2.06 ENSMUST00000077902.5
glial fibrillary acidic protein
chr7_-_97827461 2.05 ENSMUST00000040971.14
calpain 5
chr8_+_94899292 2.01 ENSMUST00000034214.8
ENSMUST00000212806.2
metallothionein 2
chr10_-_40018243 1.83 ENSMUST00000092566.8
ENSMUST00000213488.2
solute carrier family 16 (monocarboxylic acid transporters), member 10
chr11_-_79971750 1.76 ENSMUST00000103233.10
ENSMUST00000061283.15
cytokine receptor-like factor 3
chr15_+_78798116 1.70 ENSMUST00000089378.5
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr17_-_46464441 1.69 ENSMUST00000171172.3
MAD2L1 binding protein
chr4_-_156285247 1.67 ENSMUST00000085425.6
ISG15 ubiquitin-like modifier
chr7_-_100504610 1.60 ENSMUST00000156855.8
RELT tumor necrosis factor receptor
chr9_+_54606832 1.55 ENSMUST00000070070.8
DnaJ heat shock protein family (Hsp40) member A4
chr9_+_54606144 1.48 ENSMUST00000120452.8
DnaJ heat shock protein family (Hsp40) member A4
chr7_-_44785603 1.44 ENSMUST00000209467.2
predicted gene 45713
chr17_+_35069347 1.43 ENSMUST00000097343.11
ENSMUST00000173357.8
ENSMUST00000173065.8
ENSMUST00000165953.3
negative elongation factor complex member E, Rdbp
chr1_+_134109888 1.41 ENSMUST00000156873.8
chitinase-like 1
chr7_+_24246575 1.40 ENSMUST00000063249.9
X-ray repair complementing defective repair in Chinese hamster cells 1
chr4_+_129083553 1.38 ENSMUST00000106054.4
tyrosyl-tRNA synthetase
chr17_+_29171386 1.33 ENSMUST00000118762.9
ENSMUST00000057174.16
ENSMUST00000232874.2
ENSMUST00000232772.2
ENSMUST00000233334.2
ENSMUST00000150858.2
ENSMUST00000233064.2
potassium channel tetramerisation domain containing 20
chr9_+_54606798 1.31 ENSMUST00000154690.8
DnaJ heat shock protein family (Hsp40) member A4
chr2_+_78699360 1.14 ENSMUST00000028398.14
ubiquitin-conjugating enzyme E2E 3
chr1_-_74040723 1.13 ENSMUST00000190389.7
tensin 1
chr15_+_98006346 1.06 ENSMUST00000051226.8
phosphofructokinase, muscle
chr6_+_113508636 1.04 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr15_+_58004793 1.02 ENSMUST00000227142.2
ENSMUST00000226955.2
WDYHV motif containing 1
chr11_-_75918551 1.02 ENSMUST00000021207.7
refilin B
chr15_-_79571977 1.00 ENSMUST00000023061.7
Josephin domain containing 1
chr9_-_22046970 0.93 ENSMUST00000165735.9
acid phosphatase 5, tartrate resistant
chr2_-_126460575 0.93 ENSMUST00000028838.5
histidine decarboxylase
chr15_+_58004753 0.91 ENSMUST00000067563.9
WDYHV motif containing 1
chr3_-_95214443 0.90 ENSMUST00000015846.9
annexin A9
chr17_+_29171655 0.89 ENSMUST00000117672.9
ENSMUST00000153831.9
potassium channel tetramerisation domain containing 20
chr8_+_75820240 0.88 ENSMUST00000005548.8
heme oxygenase 1
chr7_-_30738471 0.86 ENSMUST00000162250.8
FXYD domain-containing ion transport regulator 5
chr8_-_106434565 0.84 ENSMUST00000013299.11
enkurin domain containing 1
chr7_+_28488380 0.84 ENSMUST00000209035.2
ENSMUST00000059857.8
Ras and Rab interactor-like
chr19_+_4242064 0.81 ENSMUST00000046094.6
protein phosphatase 1 catalytic subunit alpha
chr7_-_44785480 0.76 ENSMUST00000211246.2
ENSMUST00000210197.2
FMS-like tyrosine kinase 3 ligand
chr14_-_79718890 0.65 ENSMUST00000022601.7
WW domain binding protein 4
chr7_-_44785709 0.65 ENSMUST00000211429.2
FMS-like tyrosine kinase 3 ligand
chr13_+_55517545 0.63 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr9_-_21982637 0.62 ENSMUST00000179605.9
ENSMUST00000043922.7
zinc finger protein 653
chr9_+_66257747 0.61 ENSMUST00000042824.13
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr16_+_18695787 0.59 ENSMUST00000120532.9
ENSMUST00000004222.14
histone cell cycle regulator
chr9_+_113760376 0.59 ENSMUST00000214095.2
ENSMUST00000116492.3
ENSMUST00000216558.2
upstream binding protein 1
chr11_+_69857722 0.59 ENSMUST00000151515.2
claudin 7
chr6_+_123239076 0.57 ENSMUST00000032240.4
C-type lectin domain family 4, member d
chr17_-_35069136 0.57 ENSMUST00000046022.16
superkiller viralicidic activity 2-like (S. cerevisiae)
chr7_-_44785815 0.55 ENSMUST00000146760.7
FMS-like tyrosine kinase 3 ligand
chrX_-_52328963 0.54 ENSMUST00000074861.9
placental specific protein 1
chr11_+_3438274 0.52 ENSMUST00000064265.13
phospholipase A2, group III
chr7_-_140859034 0.51 ENSMUST00000211667.2
ENSMUST00000167790.3
ENSMUST00000046156.13
secretin
chr16_+_38383154 0.50 ENSMUST00000171687.8
ENSMUST00000002924.15
transmembrane protein 39a
chr8_-_95564881 0.48 ENSMUST00000034233.15
ENSMUST00000162538.9
cytokine induced apoptosis inhibitor 1
chr19_-_46561532 0.47 ENSMUST00000026009.10
ENSMUST00000236255.2
ADP-ribosylation factor-like 3
chr1_+_74627445 0.47 ENSMUST00000113733.10
ENSMUST00000027358.11
BCS1-like (yeast)
chr16_+_17095416 0.47 ENSMUST00000232364.2
transmembrane protein 191C
chr17_-_25652750 0.46 ENSMUST00000159610.8
ENSMUST00000159048.8
ENSMUST00000078496.12
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr14_-_55204023 0.46 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr18_-_42395207 0.46 ENSMUST00000097590.5
leucyl-tRNA synthetase
chr17_+_36134450 0.45 ENSMUST00000172846.2
flotillin 1
chr15_-_101621332 0.45 ENSMUST00000023709.7
keratin 5
chr16_-_19334384 0.45 ENSMUST00000054606.2
olfactory receptor 167
chr4_+_107659361 0.44 ENSMUST00000106731.4
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr2_+_127205117 0.44 ENSMUST00000104934.2
adrenergic receptor, alpha 2b
chr9_-_99599312 0.42 ENSMUST00000112882.9
ENSMUST00000131922.2
claudin 18
chr12_-_69629758 0.42 ENSMUST00000058639.11
valosin containing protein lysine (K) methyltransferase
chr15_-_51728893 0.42 ENSMUST00000022925.10
eukaryotic translation initiation factor 3, subunit H
chr2_-_146927365 0.41 ENSMUST00000067020.3
NK2 homeobox 4
chr16_-_56748424 0.40 ENSMUST00000210579.2
leukemia NUP98 fusion partner 1
chr9_+_108660989 0.40 ENSMUST00000192307.6
ENSMUST00000193560.6
ENSMUST00000194875.6
inositol hexaphosphate kinase 2
chrX_-_165992311 0.39 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr13_-_40887444 0.38 ENSMUST00000224665.2
transcription factor AP-2, alpha
chrX_+_49930311 0.38 ENSMUST00000114887.9
serine/threonine kinase 26
chr4_+_63478478 0.37 ENSMUST00000080336.4
transmembrane protein 268
chr10_-_82459024 0.36 ENSMUST00000183363.2
ENSMUST00000079648.12
ENSMUST00000185168.8
RIKEN cDNA 1190007I07 gene
chr17_+_25946644 0.36 ENSMUST00000237183.2
ENSMUST00000237785.2
ENSMUST00000047273.3
RNA pseudouridylate synthase domain containing 1
chr8_+_106331866 0.35 ENSMUST00000043531.10
RHO family interacting cell polarization regulator 1
chr10_-_82458760 0.35 ENSMUST00000176200.8
ENSMUST00000183416.2
RIKEN cDNA 1190007I07 gene
chr9_+_22322802 0.34 ENSMUST00000058868.9
RIKEN cDNA 9530077C05 gene
chr8_+_84293300 0.33 ENSMUST00000036996.6
NADH:ubiquinone oxidoreductase subunit B7
chr5_-_71253107 0.32 ENSMUST00000197284.5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr5_-_107745404 0.32 ENSMUST00000124140.2
glomulin, FKBP associated protein
chr16_+_17716480 0.32 ENSMUST00000055374.8
testis-specific serine kinase 2
chr1_+_74627506 0.31 ENSMUST00000113732.2
BCS1-like (yeast)
chr7_+_79939747 0.31 ENSMUST00000205864.2
vacuolar protein sorting 33B
chr14_+_55132061 0.31 ENSMUST00000172557.2
poly(A) binding protein, nuclear 1
chr17_-_56607250 0.31 ENSMUST00000233911.2
arrestin domain containing 5
chr17_+_35354655 0.30 ENSMUST00000174478.8
ENSMUST00000174281.9
ENSMUST00000173550.8
BCL2-associated athanogene 6
chr16_-_18066591 0.30 ENSMUST00000115645.10
RAN binding protein 1
chr15_+_102381929 0.30 ENSMUST00000229746.2
ENSMUST00000230211.2
ENSMUST00000230539.2
poly(rC) binding protein 2
chr17_+_24257118 0.29 ENSMUST00000059482.6
protease, serine 27
chr3_-_92594516 0.29 ENSMUST00000029524.4
late cornified envelope 1D
chr17_-_56607286 0.29 ENSMUST00000097303.3
arrestin domain containing 5
chr7_-_29894471 0.29 ENSMUST00000126116.3
calpain, small subunit 1
chr4_+_63478454 0.28 ENSMUST00000124332.8
ENSMUST00000150360.8
transmembrane protein 268
chr2_+_177834868 0.28 ENSMUST00000103065.2
phosphatase and actin regulator 3
chr10_-_116808514 0.28 ENSMUST00000092165.5
predicted gene 10271
chr1_+_78488440 0.27 ENSMUST00000152111.2
monoacylglycerol O-acyltransferase 1
chr7_-_21161866 0.27 ENSMUST00000177741.4
predicted gene 6882
chr8_+_72837021 0.27 ENSMUST00000213940.2
olfactory receptor 373
chr1_-_74627264 0.26 ENSMUST00000066986.13
zinc finger protein 142
chr15_+_103411689 0.26 ENSMUST00000226493.2
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr2_+_139335829 0.26 ENSMUST00000110083.8
ENSMUST00000047370.3
serine palmitoyltransferase, long chain base subunit 3
chr15_+_58004831 0.26 ENSMUST00000226889.2
WDYHV motif containing 1
chr18_-_61147272 0.26 ENSMUST00000025520.10
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr10_-_128505096 0.26 ENSMUST00000238610.2
ENSMUST00000238712.2
IKAROS family zinc finger 4
chr15_+_102381705 0.26 ENSMUST00000229958.2
ENSMUST00000229184.2
ENSMUST00000230728.2
ENSMUST00000230114.2
poly(rC) binding protein 2
chr18_-_42395131 0.26 ENSMUST00000236102.2
leucyl-tRNA synthetase
chr17_-_46044768 0.26 ENSMUST00000178179.2
RIKEN cDNA 1600014C23 gene
chr10_+_21469039 0.25 ENSMUST00000057341.6
RIKEN cDNA 1700020N01 gene
chr8_+_11847411 0.25 ENSMUST00000239427.2
Rho guanine nucleotide exchange factor (GEF7)
chr11_-_115158062 0.25 ENSMUST00000106554.2
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr11_-_83320281 0.25 ENSMUST00000052521.9
growth arrest-specific 2 like 2
chr4_-_140781015 0.25 ENSMUST00000102491.10
ciliary rootlet coiled-coil, rootletin
chr2_-_92201342 0.24 ENSMUST00000176810.8
ENSMUST00000090582.11
ENSMUST00000068586.13
LARGE xylosyl- and glucuronyltransferase 2
chr2_+_84867783 0.24 ENSMUST00000168266.8
ENSMUST00000130729.3
structure specific recognition protein 1
chr4_-_140780972 0.24 ENSMUST00000040222.14
ciliary rootlet coiled-coil, rootletin
chr14_+_55131568 0.24 ENSMUST00000116476.9
ENSMUST00000022808.14
ENSMUST00000150975.8
poly(A) binding protein, nuclear 1
chr7_+_140427729 0.23 ENSMUST00000106049.2
outer dense fiber of sperm tails 3
chr15_+_99024394 0.23 ENSMUST00000063517.6
spermatogenesis associated, serine-rich 2
chr11_-_102837514 0.23 ENSMUST00000057849.6
complement component 1, q subcomponent-like 1
chr12_-_8589545 0.22 ENSMUST00000095863.10
ENSMUST00000165657.3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 15
chr3_+_108000425 0.22 ENSMUST00000151326.8
guanine nucleotide binding protein, alpha transducing 2
chr7_-_103734672 0.22 ENSMUST00000057104.7
olfactory receptor 645
chr12_+_111373243 0.21 ENSMUST00000150384.3
LBH domain containing 2
chr13_-_40887244 0.21 ENSMUST00000110193.9
transcription factor AP-2, alpha
chr5_+_73563418 0.20 ENSMUST00000031040.13
ENSMUST00000065543.8
cell wall biogenesis 43 C-terminal homolog
chr1_+_166829001 0.20 ENSMUST00000126198.3
family with sequence similarity 78, member B
chr1_+_92545510 0.20 ENSMUST00000213247.2
olfactory receptor 12
chr13_-_22193900 0.20 ENSMUST00000006341.4
protease, serine 16 (thymus)
chr14_-_55204383 0.20 ENSMUST00000111456.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr15_+_103181311 0.20 ENSMUST00000100162.5
ENSMUST00000230893.2
coatomer protein complex, subunit zeta 1
chr17_+_35643818 0.19 ENSMUST00000174699.8
histocompatibility 2, Q region locus 6
chr2_-_179976458 0.19 ENSMUST00000015771.3
GATA binding protein 5
chr4_+_124880223 0.19 ENSMUST00000030687.8
R-spondin 1
chr18_+_37637317 0.19 ENSMUST00000052179.8
protocadherin beta 20
chrX_+_135723531 0.19 ENSMUST00000113085.2
proteolipid protein (myelin) 1
chr10_+_36383008 0.19 ENSMUST00000168572.8
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr15_-_48655329 0.19 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
CUB and Sushi multiple domains 3
chr9_+_58395850 0.19 ENSMUST00000085658.5
inhibitory synaptic factor 1
chr7_+_140427711 0.19 ENSMUST00000026555.12
outer dense fiber of sperm tails 3
chr7_+_126832399 0.19 ENSMUST00000056232.7
zinc finger protein 553
chr13_-_64236994 0.18 ENSMUST00000039832.7
hydroxysteroid (17-beta) dehydrogenase 3
chr1_-_74627123 0.18 ENSMUST00000027315.14
ENSMUST00000113737.8
zinc finger protein 142
chr17_-_36953554 0.18 ENSMUST00000087165.11
ENSMUST00000087167.5
histocompatibility 2, M region locus 9
chr18_+_37580692 0.18 ENSMUST00000052387.5
protocadherin beta 14
chr14_-_24054352 0.18 ENSMUST00000190339.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_166828982 0.17 ENSMUST00000165874.8
ENSMUST00000190081.7
family with sequence similarity 78, member B
chr10_-_33920300 0.17 ENSMUST00000048052.7
calcium homeostasis modulator family member 4
chr11_+_74661647 0.16 ENSMUST00000010698.13
ENSMUST00000141755.8
methyltransferase like 16
chr6_-_139478919 0.16 ENSMUST00000170650.3
RERG/RAS-like
chr13_-_64237036 0.16 ENSMUST00000222783.2
hydroxysteroid (17-beta) dehydrogenase 3
chr9_+_110485561 0.16 ENSMUST00000019803.9
ENSMUST00000196347.5
coiled-coil domain containing 12
chr13_-_59879548 0.16 ENSMUST00000052978.6
spermatogenesis associated 31 subfamily D, member 1D
chr19_-_5507532 0.16 ENSMUST00000236881.2
coiled-coil domain containing 85B
chr18_+_37575553 0.16 ENSMUST00000056915.3
protocadherin beta 13
chr3_+_54063459 0.16 ENSMUST00000029311.11
ENSMUST00000200048.5
transient receptor potential cation channel, subfamily C, member 4
chrX_+_135723420 0.16 ENSMUST00000033800.13
proteolipid protein (myelin) 1
chr4_+_103000248 0.16 ENSMUST00000106855.2
MEIR1 treanscription regulator
chr10_-_95509251 0.16 ENSMUST00000218771.2
ENSMUST00000099328.2
anaphase promoting complex C subunit 15, pseudogene
chr3_+_92864693 0.15 ENSMUST00000059053.11
late cornified envelope 3D
chr7_+_108064533 0.15 ENSMUST00000217616.3
olfactory receptor 498
chr16_+_38383182 0.15 ENSMUST00000163948.8
transmembrane protein 39a
chr13_-_64237011 0.14 ENSMUST00000166224.8
ENSMUST00000222810.2
hydroxysteroid (17-beta) dehydrogenase 3
chr18_-_15196612 0.14 ENSMUST00000168989.9
potassium channel tetramerisation domain containing 1
chr18_+_36498826 0.14 ENSMUST00000144158.2
cysteine-rich transmembrane module containing 1
chr11_-_72302520 0.14 ENSMUST00000108500.8
ENSMUST00000050226.7
smoothelin-like 2
chr1_+_75526225 0.14 ENSMUST00000154101.8
solute carrier family 4 (anion exchanger), member 3
chr2_-_85509111 0.14 ENSMUST00000099917.4
olfactory receptor 1006
chr8_-_61407760 0.14 ENSMUST00000110302.8
chloride channel, voltage-sensitive 3
chr15_-_99355623 0.14 ENSMUST00000023747.14
NCK-associated protein 5-like
chr6_-_67931692 0.13 ENSMUST00000103313.3
immunoglobulin kappa variable 9-123
chr3_-_129548954 0.13 ENSMUST00000029653.7
epidermal growth factor
chr10_+_19588318 0.13 ENSMUST00000020185.5
interleukin 20 receptor, alpha
chrX_-_71318353 0.13 ENSMUST00000064780.4
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr4_+_104224774 0.12 ENSMUST00000106830.9
disabled 1
chr7_+_3337591 0.12 ENSMUST00000203328.4
myeloid-associated differentiation marker
chr19_-_45034156 0.12 ENSMUST00000169459.4
PDZ domain containing 7
chr2_+_30485048 0.12 ENSMUST00000102853.4
CSA-conditional, T cell activation-dependent protein
chr15_-_101555815 0.12 ENSMUST00000229963.2
ENSMUST00000100184.4
predicted pseudogene 5478
chr14_+_55132030 0.12 ENSMUST00000141446.8
ENSMUST00000139985.8
poly(A) binding protein, nuclear 1
chr11_-_51153870 0.12 ENSMUST00000054226.3
cDNA sequence BC049762
chrX_-_7185424 0.12 ENSMUST00000115746.8
chloride channel, voltage-sensitive 5
chr14_+_56905698 0.11 ENSMUST00000116468.2
M-phase phosphoprotein 8
chr8_+_120339440 0.11 ENSMUST00000098361.4
adenosine deaminase domain containing 2
chr4_+_33078796 0.10 ENSMUST00000131920.8
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr7_+_126832215 0.10 ENSMUST00000106312.4
zinc finger protein 553

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.0 5.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.9 5.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.7 2.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 1.7 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.5 2.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.4 8.6 GO:0007379 segment specification(GO:0007379)
0.3 1.0 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 0.9 GO:0006788 heme oxidation(GO:0006788)
0.3 4.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 2.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.7 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.2 1.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 1.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.2 1.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.9 GO:0006548 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.2 0.7 GO:0007522 visceral muscle development(GO:0007522)
0.2 0.5 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.2 4.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 0.7 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 6.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 3.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.6 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 1.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.5 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.1 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.5 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.4 GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 1.7 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.6 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.4 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.6 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.5 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.0 0.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0097477 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477)
0.0 1.8 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.3 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.0 0.6 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.0 0.1 GO:1990768 regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.6 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.0 0.2 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 5.6 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.4 6.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 2.2 GO:0031262 Ndc80 complex(GO:0031262)
0.4 1.4 GO:0032021 NELF complex(GO:0032021)
0.2 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.4 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.2 0.6 GO:0055087 Ski complex(GO:0055087)
0.1 8.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.7 GO:0070938 contractile ring(GO:0070938)
0.1 2.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0044301 climbing fiber(GO:0044301)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0070773 protein-N-terminal glutamine amidohydrolase activity(GO:0070773)
0.6 5.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 1.7 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.4 1.8 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.3 3.6 GO:1903136 cuprous ion binding(GO:1903136)
0.3 0.9 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 3.5 GO:0008061 chitin binding(GO:0008061)
0.2 0.7 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.2 1.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 1.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 2.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.7 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 1.7 GO:0031386 protein tag(GO:0031386)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 6.4 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.9 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 5.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 4.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0031768 ghrelin receptor binding(GO:0031768)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 5.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction