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GSE58827: Dynamics of the Mouse Liver

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Results for Zfp691

Z-value: 1.04

Motif logo

Transcription factors associated with Zfp691

Gene Symbol Gene ID Gene Info
ENSMUSG00000045268.14 zinc finger protein 691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp691mm39_v1_chr4_-_119031050_119031100-0.298.5e-02Click!

Activity profile of Zfp691 motif

Sorted Z-values of Zfp691 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_22266580 8.06 ENSMUST00000051017.9
defensin beta 1
chr9_+_62765362 6.61 ENSMUST00000213643.2
ENSMUST00000034777.14
ENSMUST00000163820.3
ENSMUST00000215870.2
ENSMUST00000214633.2
ENSMUST00000215968.2
calmodulin-like 4
chr13_-_100922910 5.97 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr16_+_32427738 5.57 ENSMUST00000023486.15
transferrin receptor
chr11_-_99383938 5.44 ENSMUST00000006969.8
keratin 23
chr14_+_52091156 5.19 ENSMUST00000169070.2
ENSMUST00000074477.7
eosinophil-associated, ribonuclease A family, member 6
chr11_-_120930193 4.75 ENSMUST00000026159.6
CD7 antigen
chr2_-_120867529 4.46 ENSMUST00000102490.10
erythrocyte membrane protein band 4.2
chr6_+_41279199 4.43 ENSMUST00000031913.5
trypsin 4
chr2_-_10135449 3.36 ENSMUST00000042290.14
inter-alpha trypsin inhibitor, heavy chain 2
chr4_-_118314647 2.88 ENSMUST00000106375.2
ENSMUST00000168404.9
ENSMUST00000006556.11
myeloproliferative leukemia virus oncogene
chr13_-_55676334 2.58 ENSMUST00000047877.5
docking protein 3
chr17_-_25973288 2.38 ENSMUST00000075884.8
ENSMUST00000238120.2
ENSMUST00000236137.2
ENSMUST00000237359.2
mesothelin
chr3_+_98187743 2.27 ENSMUST00000120541.8
ENSMUST00000090746.3
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr8_+_72889073 2.26 ENSMUST00000003575.11
tropomyosin 4
chr8_+_70261323 2.24 ENSMUST00000036074.15
ENSMUST00000123453.2
Gem-interacting protein
chr8_+_72889607 2.22 ENSMUST00000238492.2
tropomyosin 4
chr7_+_127503812 2.20 ENSMUST00000151451.3
ENSMUST00000124533.3
ENSMUST00000206745.2
ENSMUST00000206140.2
branched chain ketoacid dehydrogenase kinase
chr4_-_118314707 2.05 ENSMUST00000102671.10
myeloproliferative leukemia virus oncogene
chr11_-_79414542 2.04 ENSMUST00000179322.2
ecotropic viral integration site 2b
chr14_-_70561231 1.98 ENSMUST00000151011.8
solute carrier family 39 (zinc transporter), member 14
chr12_+_86725459 1.79 ENSMUST00000021681.4
vasohibin 1
chr2_+_118943274 1.75 ENSMUST00000140939.8
ENSMUST00000028795.10
RAD51 recombinase
chr9_+_32607301 1.72 ENSMUST00000034534.13
ENSMUST00000050797.14
ENSMUST00000184887.2
E26 avian leukemia oncogene 1, 5' domain
chr1_+_134121170 1.61 ENSMUST00000038445.13
ENSMUST00000191577.2
myosin binding protein H
chr8_-_125296435 1.60 ENSMUST00000238882.2
ENSMUST00000063278.7
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chrX_-_100311824 1.59 ENSMUST00000033664.14
interleukin 2 receptor, gamma chain
chr1_+_51328265 1.59 ENSMUST00000051572.8
caveolae associated 2
chr9_-_58220469 1.44 ENSMUST00000061799.10
lysyl oxidase-like 1
chr19_-_11243530 1.40 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr1_-_181670599 1.31 ENSMUST00000193030.6
lamin B receptor
chr14_+_73379930 1.29 ENSMUST00000170370.8
ENSMUST00000164822.8
ENSMUST00000165429.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr14_+_43951187 1.27 ENSMUST00000094051.6
predicted gene 7324
chr8_+_73072877 1.26 ENSMUST00000067912.8
Kruppel-like factor 2 (lung)
chr8_-_78244412 1.24 ENSMUST00000210922.2
ENSMUST00000210519.2
Rho GTPase activating protein 10
chr12_-_113561594 1.23 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr10_-_112764879 1.18 ENSMUST00000099276.4
ataxin 7-like 3B
chr5_-_32984453 1.14 ENSMUST00000144673.3
predicted gene 20671
chr10_-_88192852 1.12 ENSMUST00000020249.2
DNA-damage regulated autophagy modulator 1
chr6_-_87510200 1.12 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr10_-_93727003 1.11 ENSMUST00000180840.8
methionine aminopeptidase 2
chr2_+_24852409 1.11 ENSMUST00000028351.9
diphthamine biosynethesis 7
chr8_-_78244578 1.08 ENSMUST00000076316.6
Rho GTPase activating protein 10
chr1_-_162641495 1.07 ENSMUST00000144916.8
ENSMUST00000140274.2
flavin containing monooxygenase 4
chr13_-_68730207 1.04 ENSMUST00000221259.2
ENSMUST00000223398.2
ENSMUST00000045827.5
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr10_+_94412116 1.01 ENSMUST00000117929.2
transmembrane and coiled coil domains 3
chr2_+_26481435 1.00 ENSMUST00000152988.9
ENSMUST00000149789.2
EGF-like domain 7
chr9_-_108329576 1.00 ENSMUST00000035232.13
ENSMUST00000195435.6
kelch domain containing 8B
chr4_+_124608569 0.99 ENSMUST00000030734.5
splicing factor 3a, subunit 3
chr19_+_11493825 0.98 ENSMUST00000163078.8
membrane-spanning 4-domains, subfamily A, member 6B
chr4_+_132262853 0.96 ENSMUST00000094657.10
ENSMUST00000105940.10
ENSMUST00000105939.10
ENSMUST00000150207.8
DnaJ heat shock protein family (Hsp40) member C8
chr8_+_92040153 0.92 ENSMUST00000069718.15
ENSMUST00000125471.8
ENSMUST00000128081.8
fat mass and obesity associated
chr9_-_50528727 0.91 ENSMUST00000131351.8
ENSMUST00000171462.8
NKAP domain containing 1
chr7_-_143203348 0.90 ENSMUST00000084396.4
ENSMUST00000075588.13
ENSMUST00000146692.8
tumor necrosis factor receptor superfamily, member 22
chr6_-_119925387 0.89 ENSMUST00000162541.8
WNK lysine deficient protein kinase 1
chr6_-_38814159 0.78 ENSMUST00000160962.8
homeodomain interacting protein kinase 2
chr7_-_143239600 0.78 ENSMUST00000208017.2
ENSMUST00000152703.2
tumor necrosis factor receptor superfamily, member 23
chr12_-_114117264 0.76 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr4_-_129517662 0.76 ENSMUST00000106035.8
ENSMUST00000150357.2
ENSMUST00000030586.15
coiled coil domain containing 28B
chr8_+_92040215 0.74 ENSMUST00000166548.9
fat mass and obesity associated
chr10_-_62438040 0.73 ENSMUST00000045866.9
DExD box helicase 21
chr12_+_69418886 0.73 ENSMUST00000050063.9
ADP-ribosylation factor 6
chr13_+_19528728 0.71 ENSMUST00000179181.3
T cell receptor gamma, constant 4
chr17_-_27816151 0.70 ENSMUST00000231742.2
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr14_+_73380163 0.69 ENSMUST00000170368.8
ENSMUST00000171767.8
ENSMUST00000163533.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_+_92040188 0.68 ENSMUST00000136802.8
fat mass and obesity associated
chr7_-_37718916 0.66 ENSMUST00000085513.6
ENSMUST00000206327.2
URI1, prefoldin-like chaperone
chr9_+_123921573 0.65 ENSMUST00000111442.3
ENSMUST00000171499.3
chemokine (C-C motif) receptor 5
chrX_+_135567124 0.58 ENSMUST00000060904.11
ENSMUST00000113100.2
ENSMUST00000128040.2
transcription elongation factor A (SII)-like 3
chr15_+_101308935 0.58 ENSMUST00000147662.8
keratin 7
chr7_+_142623241 0.55 ENSMUST00000137856.2
tumor-suppressing subchromosomal transferable fragment 4
chr10_-_77002377 0.51 ENSMUST00000081654.13
collagen, type XVIII, alpha 1
chr1_-_75186067 0.50 ENSMUST00000186173.7
galactosidase, beta 1-like
chr1_+_86454511 0.49 ENSMUST00000188533.2
prothymosin alpha
chr10_+_59839142 0.49 ENSMUST00000164083.4
activating signal cointegrator 1 complex subunit 1
chr6_+_70821481 0.48 ENSMUST00000034093.15
ENSMUST00000162950.2
eukaryotic translation initiation factor 2 alpha kinase 3
chr14_-_20398108 0.48 ENSMUST00000224412.2
ENSMUST00000022344.4
ecdysoneless cell cycle regulator
chr6_+_28475099 0.47 ENSMUST00000168362.2
staphylococcal nuclease and tudor domain containing 1
chr7_+_142622986 0.46 ENSMUST00000060433.10
ENSMUST00000133410.3
ENSMUST00000105920.8
ENSMUST00000177841.8
ENSMUST00000147995.2
tumor-suppressing subchromosomal transferable fragment 4
chr4_+_32657105 0.45 ENSMUST00000071642.11
ENSMUST00000178134.2
midasin AAA ATPase 1
chr7_+_28563255 0.45 ENSMUST00000138272.8
lectin, galactose binding, soluble 7
chr7_-_105386546 0.44 ENSMUST00000098148.6
ribosomal RNA processing 8
chr13_+_68730334 0.44 ENSMUST00000222660.2
ENSMUST00000051784.10
ENSMUST00000222631.2
ENSMUST00000223187.2
FAST kinase domains 3
chr6_-_141719536 0.43 ENSMUST00000148411.2
predicted gene 5724
chr8_-_23295603 0.42 ENSMUST00000163739.3
ENSMUST00000210656.2
adaptor-related protein complex 3, mu 2 subunit
chr2_-_131194754 0.40 ENSMUST00000059372.11
ring finger protein 24
chr10_-_27492827 0.40 ENSMUST00000092639.12
laminin, alpha 2
chr13_-_54616618 0.39 ENSMUST00000026990.6
THO complex 3
chr11_+_120358461 0.39 ENSMUST00000140862.7
ENSMUST00000106205.9
ENSMUST00000106203.9
HGF-regulated tyrosine kinase substrate
chr1_+_86454431 0.37 ENSMUST00000045897.15
ENSMUST00000186255.7
ENSMUST00000188699.7
prothymosin alpha
chr9_-_104140099 0.36 ENSMUST00000035170.13
DnaJ heat shock protein family (Hsp40) member C13
chr2_+_91095597 0.35 ENSMUST00000028691.7
ADP-ribosylation factor GTPase activating protein 2
chr14_+_73380485 0.34 ENSMUST00000170677.8
ENSMUST00000167401.8
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr4_+_125940678 0.31 ENSMUST00000030675.8
mitochondrial ribosomal protein S15
chr2_-_105832353 0.30 ENSMUST00000155811.2
DnaJ heat shock protein family (Hsp40) member C24
chr4_+_45342069 0.28 ENSMUST00000155551.8
DDB1 and CUL4 associated factor 10
chr6_+_88442391 0.28 ENSMUST00000032165.16
RuvB-like protein 1
chr11_-_116585627 0.26 ENSMUST00000079545.6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr6_-_128765449 0.26 ENSMUST00000172601.8
killer cell lectin-like receptor subfamily B member 1C
chr3_-_15397325 0.24 ENSMUST00000108361.2
predicted gene 9733
chr3_-_15640045 0.24 ENSMUST00000192382.6
ENSMUST00000195778.3
ENSMUST00000091319.7
signal-regulatory protein beta 1B
chr2_+_181138958 0.23 ENSMUST00000149163.8
ENSMUST00000000844.15
ENSMUST00000184849.8
ENSMUST00000108800.8
ENSMUST00000069712.9
tumor protein D52-like 2
chr15_+_82136598 0.23 ENSMUST00000136948.3
RIKEN cDNA 1500009C09 gene
chr1_-_138784557 0.23 ENSMUST00000112025.3
RIKEN cDNA 2310009B15 gene
chr14_-_63509131 0.22 ENSMUST00000132122.2
GATA binding protein 4
chrX_-_108056995 0.20 ENSMUST00000033597.9
high-mobility group nucleosome binding domain 5
chr17_-_23902992 0.19 ENSMUST00000085989.8
claudin 9
chr15_-_82796308 0.19 ENSMUST00000109510.10
ENSMUST00000048966.7
transcription factor 20
chr4_-_141412910 0.18 ENSMUST00000105782.2
regulatory solute carrier protein, family 1, member 1
chr8_+_89247976 0.16 ENSMUST00000034086.13
naked cuticle 1
chr10_-_59838878 0.15 ENSMUST00000182912.2
ENSMUST00000020307.11
ENSMUST00000182898.8
anaphase promoting complex subunit 16
chr2_+_181139016 0.15 ENSMUST00000108799.10
tumor protein D52-like 2
chr3_+_102377234 0.15 ENSMUST00000035952.5
ENSMUST00000198168.5
ENSMUST00000106925.9
nerve growth factor
chr18_+_65156620 0.12 ENSMUST00000080418.7
ENSMUST00000237854.2
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr6_+_115521625 0.10 ENSMUST00000130425.8
ENSMUST00000040234.9
tRNA splicing endonuclease subunit 2
chr11_-_6576030 0.08 ENSMUST00000000394.14
ENSMUST00000189268.7
ENSMUST00000136682.8
transforming growth factor beta regulated gene 4
chr1_-_135934080 0.04 ENSMUST00000166193.9
immunoglobulin-like and fibronectin type III domain containing 1
chr7_+_41282955 0.03 ENSMUST00000100275.10
ENSMUST00000131180.8
ENSMUST00000140964.8
ENSMUST00000045720.14
ENSMUST00000098508.9
zinc finger protein 788
chr15_+_44059531 0.03 ENSMUST00000038856.14
ENSMUST00000110289.4
thyrotropin releasing hormone receptor
chr1_+_133254950 0.03 ENSMUST00000178033.5
KiSS-1 metastasis-suppressor
chr8_+_12999480 0.02 ENSMUST00000110866.9
mcf.2 transforming sequence-like
chr15_-_83439818 0.02 ENSMUST00000230672.2
ENSMUST00000061882.10
malonyl CoA:ACP acyltransferase (mitochondrial)

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp691

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0035702 monocyte homeostasis(GO:0035702)
1.5 6.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.6 2.3 GO:0042245 RNA repair(GO:0042245)
0.6 1.8 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.5 1.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.4 1.8 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 5.6 GO:0033572 transferrin transport(GO:0033572)
0.3 5.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 1.6 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.2 1.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 0.4 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 0.9 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.2 0.7 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 0.7 GO:0043418 homocysteine catabolic process(GO:0043418)
0.2 0.5 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.2 1.7 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 1.1 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.7 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 2.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 2.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 4.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.2 GO:0060464 lung lobe formation(GO:0060464) diaphragm morphogenesis(GO:0060540)
0.1 1.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 3.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 2.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 1.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.7 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.3 GO:0097503 sialylation(GO:0097503)
0.0 0.9 GO:0043486 histone exchange(GO:0043486)
0.0 1.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 4.4 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 1.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 6.1 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 4.6 GO:0006936 muscle contraction(GO:0006936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.4 5.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 2.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 4.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 6.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0071203 WASH complex(GO:0071203)
0.0 4.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 5.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 2.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0004998 transferrin receptor activity(GO:0004998)
1.0 6.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.8 2.3 GO:0035516 oxidative DNA demethylase activity(GO:0035516) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.8 2.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.4 4.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.6 GO:0019976 interleukin-2 binding(GO:0019976)
0.2 1.8 GO:0000150 recombinase activity(GO:0000150)
0.1 2.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.7 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 6.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 1.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 5.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 2.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 2.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 1.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 6.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 4.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.5 6.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 5.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 4.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 4.9 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 5.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)