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GSE58827: Dynamics of the Mouse Liver

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Results for Zic3

Z-value: 0.56

Motif logo

Transcription factors associated with Zic3

Gene Symbol Gene ID Gene Info
ENSMUSG00000067860.12 zinc finger protein of the cerebellum 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic3mm39_v1_chrX_+_57076359_57076378-0.057.5e-01Click!

Activity profile of Zic3 motif

Sorted Z-values of Zic3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_24069680 2.37 ENSMUST00000205428.2
ENSMUST00000171904.3
ENSMUST00000205626.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_+_115790768 1.73 ENSMUST00000152171.8
small integral membrane protein 5
chr12_-_76756772 1.71 ENSMUST00000166101.2
spectrin beta, erythrocytic
chr7_-_16796309 1.70 ENSMUST00000153833.2
ENSMUST00000108492.9
hypoxia inducible factor 3, alpha subunit
chr18_-_78185334 1.68 ENSMUST00000160639.2
solute carrier family 14 (urea transporter), member 1
chr11_-_85030761 1.58 ENSMUST00000108075.9
ubiquitin specific peptidase 32
chrX_+_55500170 1.32 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
integrator complex subunit 6 like
chr1_+_82817794 1.31 ENSMUST00000186043.2
ArfGAP with FG repeats 1
chr1_+_82817388 1.20 ENSMUST00000190052.7
ENSMUST00000063380.11
ENSMUST00000187899.7
ENSMUST00000186302.7
ENSMUST00000190046.7
ArfGAP with FG repeats 1
chr11_+_115790951 1.20 ENSMUST00000142089.2
ENSMUST00000131566.2
small integral membrane protein 5
chr2_-_170269748 1.11 ENSMUST00000013667.3
ENSMUST00000109152.9
ENSMUST00000068137.11
breast carcinoma amplified sequence 1
chr1_-_133728779 1.11 ENSMUST00000143567.8
ATPase, Ca++ transporting, plasma membrane 4
chr2_+_29759495 1.09 ENSMUST00000047521.7
ENSMUST00000134152.2
cerebral endothelial cell adhesion molecule
chr8_-_86091946 1.07 ENSMUST00000034133.14
myosin light chain kinase 3
chr9_-_107960528 1.01 ENSMUST00000159372.3
ENSMUST00000160249.8
ring finger protein 123
chr13_+_6598185 0.95 ENSMUST00000021611.10
ENSMUST00000222485.2
pitrilysin metallepetidase 1
chr11_-_90578397 0.95 ENSMUST00000107869.9
ENSMUST00000154599.2
ENSMUST00000107868.8
ENSMUST00000020849.9
target of myb1-like 1 (chicken)
chr14_-_73563212 0.92 ENSMUST00000022701.7
RB transcriptional corepressor 1
chr11_+_69806866 0.89 ENSMUST00000134581.2
G protein pathway suppressor 2
chr7_+_110372860 0.89 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chrX_+_139857688 0.88 ENSMUST00000239541.1
autophagy related 4A, cysteine peptidase
chr19_-_5776268 0.86 ENSMUST00000075606.6
ENSMUST00000236215.2
ENSMUST00000235730.2
ENSMUST00000237081.2
ENSMUST00000049295.15
EH domain binding protein 1-like 1
chrX_+_139857640 0.83 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr2_+_78699360 0.79 ENSMUST00000028398.14
ubiquitin-conjugating enzyme E2E 3
chr4_+_52439237 0.79 ENSMUST00000102915.10
ENSMUST00000117280.8
ENSMUST00000142227.3
structural maintenance of chromosomes 2
chr7_+_78563964 0.76 ENSMUST00000120331.4
interferon-stimulated protein
chr2_+_29780122 0.75 ENSMUST00000113762.8
ENSMUST00000113765.8
outer dense fiber of sperm tails 2
chr10_+_82821304 0.75 ENSMUST00000040110.8
carbohydrate sulfotransferase 11
chr11_+_53410697 0.74 ENSMUST00000120878.9
ENSMUST00000147912.2
septin 8
chr14_+_30853010 0.70 ENSMUST00000227096.2
5'-nucleotidase domain containing 2
chr11_-_4544751 0.68 ENSMUST00000109943.10
myotubularin related protein 3
chr17_-_24428351 0.68 ENSMUST00000024931.6
netrin 3
chr13_+_81931196 0.67 ENSMUST00000022009.10
ENSMUST00000223793.2
centrin 3
chr5_+_34731152 0.67 ENSMUST00000001108.11
ENSMUST00000114340.9
adducin 1 (alpha)
chr5_+_34731008 0.66 ENSMUST00000114338.9
adducin 1 (alpha)
chr2_+_29779750 0.66 ENSMUST00000113763.8
ENSMUST00000113757.8
ENSMUST00000113756.8
ENSMUST00000133233.8
ENSMUST00000113759.9
ENSMUST00000113755.8
ENSMUST00000137558.8
ENSMUST00000046571.14
outer dense fiber of sperm tails 2
chr11_-_120520954 0.66 ENSMUST00000106180.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr11_+_53410552 0.65 ENSMUST00000108987.8
ENSMUST00000121334.8
ENSMUST00000117061.8
septin 8
chr2_+_84670956 0.65 ENSMUST00000111625.2
solute carrier family 43, member 1
chr6_-_86646118 0.65 ENSMUST00000001184.10
MAX dimerization protein 1
chr1_-_177624017 0.64 ENSMUST00000016105.9
adenylosuccinate synthetase, non muscle
chr5_+_137756407 0.64 ENSMUST00000141733.8
ENSMUST00000110985.2
TSC22 domain family, member 4
chr10_+_80972368 0.64 ENSMUST00000119606.8
ENSMUST00000146895.2
ENSMUST00000121840.8
zinc finger and BTB domain containing 7a
chr18_-_35795233 0.64 ENSMUST00000025209.12
ENSMUST00000096573.4
spermatogenesis associated 24
chr17_+_47906985 0.63 ENSMUST00000182539.8
cyclin D3
chr7_-_103463120 0.63 ENSMUST00000098192.4
hemoglobin, beta adult t chain
chr7_+_44117444 0.62 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josephin domain containing 2
chr7_-_48530777 0.62 ENSMUST00000058745.15
E2F transcription factor 8
chr5_+_34731087 0.61 ENSMUST00000147574.8
ENSMUST00000146295.8
adducin 1 (alpha)
chr6_-_71417607 0.61 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chrX_+_12454031 0.60 ENSMUST00000033313.3
ATPase, H+ transporting, lysosomal accessory protein 2
chr2_-_104647041 0.59 ENSMUST00000117237.2
ENSMUST00000231375.2
glutamine and serine rich 1
chr5_-_138169476 0.56 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr7_+_44117475 0.55 ENSMUST00000118493.8
Josephin domain containing 2
chr15_-_101833160 0.54 ENSMUST00000023797.8
keratin 4
chr7_+_44117404 0.54 ENSMUST00000035844.11
Josephin domain containing 2
chr17_-_71617945 0.53 ENSMUST00000232777.2
ENSMUST00000024849.11
elastin microfibril interfacer 2
chr5_-_138169509 0.53 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr7_+_44117511 0.53 ENSMUST00000121922.3
ENSMUST00000208117.2
Josephin domain containing 2
chr16_+_36832119 0.51 ENSMUST00000071452.12
ENSMUST00000054034.7
polymerase (DNA directed), theta
chrX_+_10583629 0.51 ENSMUST00000115524.8
ENSMUST00000008179.7
ENSMUST00000156321.2
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr6_-_122587005 0.51 ENSMUST00000032211.5
growth differentiation factor 3
chr6_+_87755046 0.50 ENSMUST00000032133.5
glycoprotein 9 (platelet)
chr4_+_123798625 0.50 ENSMUST00000030400.14
MYC binding protein
chr2_+_126850613 0.50 ENSMUST00000110394.8
ENSMUST00000002063.15
adaptor-related protein complex AP-4, epsilon 1
chr5_-_138169253 0.50 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr3_+_14545751 0.49 ENSMUST00000037321.8
ENSMUST00000120484.8
ENSMUST00000120801.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr6_+_116241146 0.48 ENSMUST00000112900.9
ENSMUST00000036503.14
ENSMUST00000223495.2
zinc finger, AN1-type domain 4
chr11_-_34724458 0.48 ENSMUST00000093191.3
spindle apparatus coiled-coil protein 1
chr18_-_67857594 0.48 ENSMUST00000120934.8
ENSMUST00000025420.14
ENSMUST00000122412.2
protein tyrosine phosphatase, non-receptor type 2
chr15_-_98851423 0.48 ENSMUST00000134214.3
predicted gene, 49450
chr8_+_70953766 0.47 ENSMUST00000127983.2
cytokine receptor-like factor 1
chr10_+_80641067 0.47 ENSMUST00000036016.6
anti-Mullerian hormone
chr17_+_84013575 0.46 ENSMUST00000112350.8
ENSMUST00000112349.9
ENSMUST00000112352.10
ENSMUST00000067826.15
metastasis associated 3
chr17_-_71617968 0.46 ENSMUST00000233057.2
elastin microfibril interfacer 2
chr3_+_63203235 0.46 ENSMUST00000194134.6
membrane metallo endopeptidase
chr5_-_37874461 0.46 ENSMUST00000094836.6
serine/threonine kinase 32B
chr6_-_51446752 0.45 ENSMUST00000204188.3
ENSMUST00000203220.3
ENSMUST00000114459.8
ENSMUST00000090002.10
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_+_62754252 0.45 ENSMUST00000124984.2
ceroid-lipofuscinosis, neuronal 6
chr13_+_81931642 0.44 ENSMUST00000224574.2
centrin 3
chr2_+_30306045 0.44 ENSMUST00000042055.10
protein phosphatase 2 protein activator
chr7_-_126398343 0.44 ENSMUST00000032934.12
aldolase A, fructose-bisphosphate
chr15_-_64886753 0.43 ENSMUST00000110100.3
predicted gene, 21961
chr6_+_52691204 0.43 ENSMUST00000138040.8
ENSMUST00000129660.2
Tax1 (human T cell leukemia virus type I) binding protein 1
chrX_+_36390430 0.43 ENSMUST00000016553.5
NFKB activating protein
chr4_+_123798690 0.42 ENSMUST00000106202.4
MYC binding protein
chr11_+_87628356 0.42 ENSMUST00000093955.12
SPT4A, DSIF elongation factor subunit
chrX_-_139857424 0.42 ENSMUST00000033805.15
ENSMUST00000112978.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr9_-_32255556 0.42 ENSMUST00000214223.2
potassium inwardly-rectifying channel, subfamily J, member 5
chr9_-_88364593 0.42 ENSMUST00000173801.8
ENSMUST00000069221.12
ENSMUST00000172508.2
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_-_146479323 0.42 ENSMUST00000032427.15
integrator complex subunit 13
chr7_-_132454332 0.41 ENSMUST00000120425.8
ENSMUST00000033257.15
EEF1A lysine methyltransferase 2
chr10_-_127358231 0.41 ENSMUST00000219239.2
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_-_78642480 0.41 ENSMUST00000059468.6
cyclin Q
chr9_+_107464841 0.41 ENSMUST00000010192.11
interferon-related developmental regulator 2
chr7_+_90091937 0.41 ENSMUST00000061767.5
CREB/ATF bZIP transcription factor
chr15_-_79976016 0.41 ENSMUST00000185306.3
ribosomal protein L3
chr5_-_110927803 0.40 ENSMUST00000112426.8
pseudouridine synthase 1
chr1_-_120197979 0.40 ENSMUST00000112639.8
STEAP family member 3
chr11_+_72889889 0.40 ENSMUST00000021141.14
purinergic receptor P2X, ligand-gated ion channel, 1
chr12_+_26519203 0.40 ENSMUST00000020969.5
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr9_-_32255533 0.40 ENSMUST00000216033.2
potassium inwardly-rectifying channel, subfamily J, member 5
chr11_+_60428788 0.40 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr1_+_134333506 0.39 ENSMUST00000027726.14
cytochrome b5 reductase 1
chr7_-_110581652 0.39 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr6_-_124790029 0.39 ENSMUST00000149610.3
triosephosphate isomerase 1
chr1_-_52271455 0.38 ENSMUST00000114512.8
glutaminase
chr10_-_127358300 0.38 ENSMUST00000026470.6
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_-_126399208 0.38 ENSMUST00000133514.8
ENSMUST00000151137.8
aldolase A, fructose-bisphosphate
chr10_-_116385007 0.37 ENSMUST00000164088.8
CCR4-NOT transcription complex, subunit 2
chr9_-_45923908 0.37 ENSMUST00000217514.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr5_-_107873883 0.37 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr15_+_78294154 0.37 ENSMUST00000229739.2
mercaptopyruvate sulfurtransferase
chr9_-_103357564 0.37 ENSMUST00000124310.5
beaded filament structural protein 2, phakinin
chr10_-_30679289 0.37 ENSMUST00000215725.2
nuclear receptor coactivator 7
chr1_-_155848917 0.37 ENSMUST00000138762.8
centrosomal protein 350
chr11_+_96679976 0.36 ENSMUST00000093943.10
chromobox 1
chr11_-_113600838 0.35 ENSMUST00000018871.8
cleavage and polyadenylation specific factor 4-like
chr9_-_123507937 0.35 ENSMUST00000040960.13
solute carrier family 6 (neurotransmitter transporter), member 20A
chr9_+_55056648 0.35 ENSMUST00000121677.8
ubiquitin-conjugating enzyme E2Q family member 2
chr7_+_113113061 0.35 ENSMUST00000129087.8
ENSMUST00000067929.15
ENSMUST00000164745.8
ENSMUST00000136158.8
fatty acyl CoA reductase 1
chr15_+_79975520 0.34 ENSMUST00000009728.13
ENSMUST00000009727.12
synaptogyrin 1
chr12_+_111387023 0.34 ENSMUST00000220852.2
exocyst complex component 3-like 4
chr7_-_103778992 0.34 ENSMUST00000053743.6
ubiquilin 5
chr19_+_36325683 0.33 ENSMUST00000225920.2
polycomb group ring finger 5
chr9_-_123507847 0.33 ENSMUST00000170591.2
ENSMUST00000171647.9
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_-_20973337 0.33 ENSMUST00000141298.9
ENSMUST00000125783.3
Rho GTPase activating protein 21
chr7_-_37806912 0.33 ENSMUST00000108023.10
cyclin E1
chr1_-_13444249 0.33 ENSMUST00000068304.13
ENSMUST00000006037.13
nuclear receptor coactivator 2
chr1_+_181952302 0.33 ENSMUST00000111018.2
ENSMUST00000027792.6
signal recognition particle 9
chr17_+_23879448 0.32 ENSMUST00000062967.10
BICD family like cargo adaptor 2
chr14_+_54713557 0.32 ENSMUST00000164766.8
rad and gem related GTP binding protein 2
chr19_+_5928649 0.32 ENSMUST00000136833.8
ENSMUST00000141362.2
solute carrier family 25, member 45
chr5_-_92583078 0.31 ENSMUST00000038514.15
nucleoporin 54
chr6_+_146479357 0.31 ENSMUST00000067404.13
ENSMUST00000111663.9
ENSMUST00000058245.5
FGFR1 oncogene partner 2
chr4_-_152216322 0.31 ENSMUST00000105653.8
espin
chrX_-_74460168 0.30 ENSMUST00000033543.14
ENSMUST00000149863.3
ENSMUST00000114081.2
C-x(9)-C motif containing 4
mature T cell proliferation 1
chr11_+_106265645 0.30 ENSMUST00000106816.8
proline rich 29
chr11_+_96680061 0.30 ENSMUST00000079702.4
chromobox 1
chr3_-_132389584 0.30 ENSMUST00000196206.5
ENSMUST00000029663.11
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr19_-_5711650 0.29 ENSMUST00000236006.2
signal-induced proliferation associated gene 1
chr17_+_29899420 0.29 ENSMUST00000130052.9
cap methyltransferase 1
chrX_+_72108393 0.29 ENSMUST00000060418.8
paraneoplastic antigen MA3
chr7_+_18618605 0.28 ENSMUST00000032573.8
peptidoglycan recognition protein 1
chr7_+_113113037 0.28 ENSMUST00000033018.15
fatty acyl CoA reductase 1
chr7_-_126391657 0.28 ENSMUST00000032936.8
protein phosphatase 4, catalytic subunit
chr5_-_66308421 0.28 ENSMUST00000200775.4
ENSMUST00000094756.11
RNA binding motif protein 47
chr3_-_144425819 0.27 ENSMUST00000199531.5
ENSMUST00000199854.5
SH3-domain GRB2-like B1 (endophilin)
chr5_-_123859070 0.27 ENSMUST00000031376.12
zinc finger, CCHC domain containing 8
chr8_+_106587268 0.27 ENSMUST00000212610.2
ENSMUST00000212484.2
ENSMUST00000212200.2
nuclear transport factor 2
chr5_+_37332834 0.27 ENSMUST00000208827.2
ENSMUST00000207619.2
predicted gene 1043
chr11_-_102207486 0.26 ENSMUST00000146896.9
ENSMUST00000079589.11
upstream binding transcription factor, RNA polymerase I
chr8_-_19000947 0.26 ENSMUST00000055503.12
ENSMUST00000095438.10
X-linked Kx blood group related 5
chr11_+_96679944 0.26 ENSMUST00000018810.10
chromobox 1
chr2_-_103627334 0.26 ENSMUST00000111147.8
cell cycle associated protein 1
chr2_+_119505543 0.26 ENSMUST00000028767.9
RTF1, Paf1/RNA polymerase II complex component
chr1_+_129201081 0.25 ENSMUST00000073527.13
ENSMUST00000040311.14
thrombospondin, type I, domain containing 7B
chr6_-_143045844 0.25 ENSMUST00000204140.2
C2 calcium-dependent domain containing 5
chr11_+_106265660 0.25 ENSMUST00000188561.7
ENSMUST00000190795.7
ENSMUST00000185986.7
ENSMUST00000190268.2
proline rich 29
chr7_+_45199259 0.25 ENSMUST00000210797.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr12_+_69771761 0.25 ENSMUST00000222950.2
distal membrane arm assembly complex 2 like
chr10_-_127031578 0.25 ENSMUST00000038217.14
ENSMUST00000130855.8
ENSMUST00000116229.2
ENSMUST00000144322.8
deltex 3, E3 ubiquitin ligase
chrX_+_72030945 0.25 ENSMUST00000164800.8
ENSMUST00000114546.9
zinc finger protein 185
chr11_-_98040377 0.25 ENSMUST00000103143.10
F-box and leucine-rich repeat protein 20
chr5_-_145077048 0.25 ENSMUST00000031627.9
PDGFA associated protein 1
chr16_-_32630847 0.25 ENSMUST00000179384.3
somatomedin B domain containing 1
chr2_-_153286361 0.25 ENSMUST00000109784.2
nucleolar protein 4-like
chr5_+_92285748 0.24 ENSMUST00000031355.10
ENSMUST00000202155.2
USO1 vesicle docking factor
chr2_+_84867554 0.24 ENSMUST00000077798.13
structure specific recognition protein 1
chr12_+_83678987 0.24 ENSMUST00000048155.16
ENSMUST00000182618.8
ENSMUST00000183154.8
ENSMUST00000182036.8
ENSMUST00000182347.8
RNA binding motif protein 25
chr5_-_123859153 0.24 ENSMUST00000196282.5
zinc finger, CCHC domain containing 8
chr5_+_115417725 0.24 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chr8_+_106587212 0.24 ENSMUST00000008594.9
nuclear transport factor 2
chr9_+_21746785 0.24 ENSMUST00000058777.8
angiopoietin-like 8
chr1_+_75483721 0.23 ENSMUST00000037330.5
inhibin alpha
chr2_+_53082079 0.23 ENSMUST00000028336.7
ADP-ribosylation factor-like 6 interacting protein 6
chr18_-_46874611 0.23 ENSMUST00000035648.6
autophagy related 12
chr16_+_32151056 0.23 ENSMUST00000115151.5
ENSMUST00000232137.2
UBX domain protein 7
chr1_-_84817000 0.23 ENSMUST00000186648.7
thyroid hormone receptor interactor 12
chr4_+_3940747 0.23 ENSMUST00000119403.2
coiled-coil-helix-coiled-coil-helix domain containing 7
chr18_-_35795175 0.23 ENSMUST00000236574.2
ENSMUST00000236971.2
spermatogenesis associated 24
chr12_-_33142858 0.23 ENSMUST00000095774.3
cadherin-related family member 3
chr7_-_43906802 0.23 ENSMUST00000107945.8
ENSMUST00000118216.8
acid phosphatase 4
chr3_-_40856935 0.22 ENSMUST00000099123.5
RIKEN cDNA 1700034I23 gene
chr10_-_49664839 0.22 ENSMUST00000220263.2
ENSMUST00000218823.2
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr13_-_58550290 0.22 ENSMUST00000043269.14
ENSMUST00000177060.8
ENSMUST00000224182.2
ENSMUST00000176207.8
heterogeneous nuclear ribonucleoprotein K
chr16_+_20536545 0.22 ENSMUST00000231656.2
polymerase (RNA) II (DNA directed) polypeptide H
chr11_-_102207516 0.22 ENSMUST00000107115.8
ENSMUST00000128016.2
upstream binding transcription factor, RNA polymerase I
chr7_-_100306160 0.22 ENSMUST00000107046.8
ENSMUST00000107045.9
ENSMUST00000139708.9
pleckstrin homology domain containing, family B (evectins) member 1
chr12_+_3622379 0.21 ENSMUST00000173199.8
ENSMUST00000164578.9
ENSMUST00000174479.8
ENSMUST00000173240.8
ENSMUST00000174663.8
ENSMUST00000173736.8
dystrobrevin, beta
chr11_+_66969119 0.21 ENSMUST00000108689.8
ENSMUST00000007301.14
ENSMUST00000165221.2
myosin, heavy polypeptide 3, skeletal muscle, embryonic
chr14_-_34096574 0.21 ENSMUST00000023826.5
synuclein, gamma
chr2_-_102903680 0.21 ENSMUST00000132449.8
ENSMUST00000111183.2
ENSMUST00000011058.9
pyruvate dehydrogenase complex, component X
chr13_-_63579497 0.21 ENSMUST00000160931.2
ENSMUST00000099444.10
ENSMUST00000220684.2
ENSMUST00000161977.8
ENSMUST00000163091.8
Fanconi anemia, complementation group C
chr12_-_70158348 0.20 ENSMUST00000220689.2
ninein
chr5_-_66308666 0.20 ENSMUST00000201561.4
RNA binding motif protein 47
chr13_+_51799268 0.20 ENSMUST00000075853.6
CDC28 protein kinase regulatory subunit 2
chr4_+_156300325 0.20 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr12_-_69771604 0.20 ENSMUST00000021370.10
L-2-hydroxyglutarate dehydrogenase
chr18_+_37453427 0.20 ENSMUST00000078271.4
protocadherin beta 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.3 0.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.3 1.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 0.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 1.7 GO:0051697 protein delipidation(GO:0051697)
0.2 0.9 GO:1903943 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.9 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.9 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.2 1.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 0.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.6 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.5 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.2 0.5 GO:1990428 miRNA transport(GO:1990428)
0.1 2.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.4 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.4 GO:0046072 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.1 1.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.5 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.6 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 2.5 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.6 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.3 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.9 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.2 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 0.6 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.1 0.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.2 GO:1990751 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.1 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.2 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.2 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.3 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0090649 rRNA export from nucleus(GO:0006407) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.3 GO:0045900 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) negative regulation of translational elongation(GO:0045900)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0031283 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 1.7 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.4 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0019043 establishment of viral latency(GO:0019043)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.5 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0097402 neuroblast migration(GO:0097402)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:1901080 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of hindgut contraction(GO:0060450) regulation of relaxation of smooth muscle(GO:1901080) positive regulation of relaxation of smooth muscle(GO:1901082)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.0 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 1.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 1.0 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.1 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 2.2 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:0021852 pyramidal neuron migration(GO:0021852)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0008091 spectrin(GO:0008091)
0.2 0.9 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0030312 external encapsulating structure(GO:0030312)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 1.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.8 GO:0070552 BRISC complex(GO:0070552)
0.1 0.2 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.9 GO:0001940 male pronucleus(GO:0001940)
0.1 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937) GAIT complex(GO:0097452)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0060473 cortical granule(GO:0060473)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.3 2.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 0.8 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 1.7 GO:0015265 urea channel activity(GO:0015265)
0.2 0.6 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.2 0.6 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 0.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0004798 thymidylate kinase activity(GO:0004798)
0.1 0.4 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 1.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.8 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 1.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.7 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.4 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 0.2 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.1 1.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.3 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 1.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.3 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 3.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6