Project

GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Zic4

Z-value: 0.97

Motif logo

Transcription factors associated with Zic4

Gene Symbol Gene ID Gene Info
ENSMUSG00000036972.15 zinc finger protein of the cerebellum 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic4mm39_v1_chr9_+_91260688_91260700-0.231.8e-01Click!

Activity profile of Zic4 motif

Sorted Z-values of Zic4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_107893676 4.22 ENSMUST00000066530.7
ENSMUST00000012348.9
glutathione S-transferase, mu 2
chr7_-_34914675 2.92 ENSMUST00000118444.3
ENSMUST00000122409.8
low density lipoprotein receptor-related protein 3
chr12_-_102671154 2.62 ENSMUST00000178697.2
ENSMUST00000046518.12
inositol 1,3,4-triphosphate 5/6 kinase
chr17_-_45904540 2.18 ENSMUST00000163905.8
ENSMUST00000167692.8
solute carrier family 29 (nucleoside transporters), member 1
chr11_+_98932062 2.05 ENSMUST00000017637.13
insulin-like growth factor binding protein 4
chr17_-_34250616 1.99 ENSMUST00000169397.9
solute carrier family 39 (zinc transporter), member 7
chr16_-_18245352 1.92 ENSMUST00000000335.12
catechol-O-methyltransferase
chr11_+_101358990 1.87 ENSMUST00000001347.7
Rho family GTPase 2
chr17_-_34250474 1.84 ENSMUST00000171872.3
ENSMUST00000025186.16
solute carrier family 39 (zinc transporter), member 7
chr15_+_7159038 1.77 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr11_+_57692399 1.77 ENSMUST00000020826.6
SAP30-like
chr4_-_124744454 1.66 ENSMUST00000125776.8
ENSMUST00000163946.2
ENSMUST00000106190.10
RIKEN cDNA 1110065P20 gene
chr1_+_131890679 1.65 ENSMUST00000191034.2
ENSMUST00000177943.8
predicted gene 29103
solute carrier family 45, member 3
chr7_+_28466160 1.65 ENSMUST00000122915.8
ENSMUST00000072965.5
ENSMUST00000170068.9
sirtuin 2
chr19_+_4905158 1.64 ENSMUST00000119694.3
ENSMUST00000237504.2
ENSMUST00000237011.2
cathepsin F
chr9_-_107109108 1.55 ENSMUST00000044532.11
dedicator of cyto-kinesis 3
chr4_+_141095415 1.54 ENSMUST00000006380.5
family with sequence similarity 131, member C
chr17_+_26332260 1.53 ENSMUST00000235821.2
ENSMUST00000025010.14
ENSMUST00000237058.2
post-glycosylphosphatidylinositol attachment to proteins 6
chr4_+_152423344 1.52 ENSMUST00000005175.5
chromodomain helicase DNA binding protein 5
chr7_+_142660971 1.48 ENSMUST00000009689.11
potassium voltage-gated channel, subfamily Q, member 1
chr17_-_45906768 1.47 ENSMUST00000164618.8
ENSMUST00000097317.10
ENSMUST00000170113.8
solute carrier family 29 (nucleoside transporters), member 1
chr4_-_124744266 1.39 ENSMUST00000137769.3
RIKEN cDNA 1110065P20 gene
chr13_-_95359543 1.38 ENSMUST00000162292.8
phosphodiesterase 8B
chr7_+_127400016 1.34 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_+_127399776 1.30 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_-_32186721 1.29 ENSMUST00000191501.2
solute carrier family 18 (vesicular monoamine), member 3
chr12_-_98541293 1.25 ENSMUST00000110113.3
potassium channel, subfamily K, member 10
chr14_-_47426863 1.21 ENSMUST00000089959.7
GTP cyclohydrolase 1
chr12_-_98540944 1.20 ENSMUST00000221305.2
potassium channel, subfamily K, member 10
chr7_-_97228589 1.20 ENSMUST00000151840.2
ENSMUST00000135998.8
ENSMUST00000144858.8
ENSMUST00000146605.8
ENSMUST00000072725.12
ENSMUST00000138060.3
ENSMUST00000154853.8
ENSMUST00000136757.8
ENSMUST00000124552.3
adipogenesis associated Mth938 domain containing
chr1_-_13061333 1.18 ENSMUST00000115403.9
ENSMUST00000136197.8
ENSMUST00000115402.8
solute carrier organic anion transporter family, member 5A1
chrX_+_137815171 1.18 ENSMUST00000064937.14
ENSMUST00000113052.8
Nik related kinase
chr16_+_20551853 1.16 ENSMUST00000115423.8
ENSMUST00000007171.13
ENSMUST00000232646.2
chordin
chr6_+_83031502 1.16 ENSMUST00000092618.9
ancient ubiquitous protein 1
chr7_-_44320244 1.14 ENSMUST00000048102.15
myosin, heavy polypeptide 14
chr9_-_58462720 1.12 ENSMUST00000165365.3
CD276 antigen
chr7_+_27290969 1.11 ENSMUST00000108344.9
thymoma viral proto-oncogene 2
chr7_+_27291126 1.11 ENSMUST00000167435.8
thymoma viral proto-oncogene 2
chr7_+_127399789 1.10 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr5_+_115373895 1.09 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr11_+_98932586 1.08 ENSMUST00000177092.8
insulin-like growth factor binding protein 4
chr2_-_143853122 1.05 ENSMUST00000016072.12
ENSMUST00000037875.6
ribosome binding protein 1
chr12_-_5425682 1.05 ENSMUST00000020958.9
kelch-like 29
chr6_-_115228800 1.04 ENSMUST00000205131.2
tissue inhibitor of metalloproteinase 4
chr10_+_77522403 1.01 ENSMUST00000092366.4
thrombospondin type laminin G domain and EAR repeats
chr2_-_152793376 0.98 ENSMUST00000123121.9
dual specificity phosphatase-like 15
chr14_-_24054352 0.97 ENSMUST00000190339.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_-_29323500 0.95 ENSMUST00000115237.8
neurotrimin
chr17_+_37356872 0.95 ENSMUST00000174456.8
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_127399848 0.95 ENSMUST00000139068.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr17_-_24752683 0.95 ENSMUST00000061764.14
RAB26, member RAS oncogene family
chr4_+_152423075 0.95 ENSMUST00000030775.12
ENSMUST00000164662.8
chromodomain helicase DNA binding protein 5
chr14_+_33662976 0.95 ENSMUST00000100720.2
growth differentiation factor 2
chr14_-_118289557 0.95 ENSMUST00000022725.4
dopachrome tautomerase
chr13_+_15637831 0.94 ENSMUST00000141194.8
GLI-Kruppel family member GLI3
chr4_+_124744472 0.93 ENSMUST00000102628.11
yrdC domain containing (E.coli)
chr10_-_81186025 0.90 ENSMUST00000122993.8
high mobility group 20B
chr2_-_152793469 0.90 ENSMUST00000037715.7
dual specificity phosphatase-like 15
chr2_-_25124240 0.90 ENSMUST00000006638.8
solute carrier family 34 (sodium phosphate), member 3
chrX_+_41238410 0.89 ENSMUST00000127618.8
stromal antigen 2
chr15_+_74435587 0.89 ENSMUST00000185682.7
ENSMUST00000170845.8
ENSMUST00000187599.2
adhesion G protein-coupled receptor B1
chr19_+_47167444 0.88 ENSMUST00000235326.2
neuralized E3 ubiquitin protein ligase 1A
chr17_-_29456750 0.88 ENSMUST00000137727.3
copine V
chr14_+_70768289 0.86 ENSMUST00000226548.2
leucine-rich repeat LGI family, member 3
chr11_+_99755302 0.86 ENSMUST00000092694.4
predicted gene 11559
chr11_-_78313043 0.85 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr14_+_70768257 0.85 ENSMUST00000047331.8
leucine-rich repeat LGI family, member 3
chr6_+_22288220 0.84 ENSMUST00000128245.8
ENSMUST00000031681.10
ENSMUST00000148639.2
wingless-type MMTV integration site family, member 16
chr11_-_102837514 0.84 ENSMUST00000057849.6
complement component 1, q subcomponent-like 1
chr2_-_152793607 0.83 ENSMUST00000109811.4
dual specificity phosphatase-like 15
chr17_-_83939316 0.83 ENSMUST00000234613.2
ENSMUST00000051482.2
potassium voltage-gated channel, subfamily G, member 3
chr7_-_16020668 0.82 ENSMUST00000150528.9
ENSMUST00000118976.9
ENSMUST00000146609.3
coiled-coil domain containing 9
chr2_-_165076609 0.81 ENSMUST00000065438.13
cadherin 22
chr19_+_48194464 0.81 ENSMUST00000078880.6
sortilin-related VPS10 domain containing receptor 3
chr7_+_49624978 0.81 ENSMUST00000107603.2
NEL-like 1
chr19_-_60456742 0.80 ENSMUST00000051277.4
prolactin releasing hormone receptor
chr8_+_93687561 0.80 ENSMUST00000072939.8
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr6_-_39095144 0.79 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chr2_-_144173615 0.78 ENSMUST00000103171.10
ovo like zinc finger 2
chr10_-_81186137 0.78 ENSMUST00000167481.8
high mobility group 20B
chr6_-_48422759 0.77 ENSMUST00000114561.9
zinc finger protein 467
chr4_-_129015027 0.76 ENSMUST00000030572.10
hippocalcin
chr1_-_166066298 0.76 ENSMUST00000038782.4
ENSMUST00000194057.6
maelstrom spermatogenic transposon silencer
chr17_-_51486196 0.76 ENSMUST00000024717.10
ENSMUST00000224528.2
TBC1 domain family, member 5
chr15_-_97902576 0.75 ENSMUST00000023123.15
collagen, type II, alpha 1
chr11_-_78388284 0.74 ENSMUST00000108287.10
sterile alpha and HEAT/Armadillo motif containing 1
chr2_+_120807498 0.73 ENSMUST00000067582.14
transmembrane protein 62
chr1_-_37758863 0.73 ENSMUST00000160589.2
capping protein inhibiting regulator of actin like
chr13_+_15637786 0.72 ENSMUST00000130065.8
GLI-Kruppel family member GLI3
chr19_+_37423198 0.72 ENSMUST00000025944.9
hematopoietically expressed homeobox
chr11_+_69891398 0.69 ENSMUST00000019362.15
ENSMUST00000190940.2
dishevelled segment polarity protein 2
chr7_+_139414057 0.69 ENSMUST00000026548.14
adhesion G protein-coupled receptor A1
chr11_-_116226175 0.69 ENSMUST00000036215.8
forkhead box J1
chr13_+_15638466 0.69 ENSMUST00000110510.4
GLI-Kruppel family member GLI3
chr15_-_97902515 0.67 ENSMUST00000088355.12
collagen, type II, alpha 1
chr8_-_45835234 0.67 ENSMUST00000093526.13
family with sequence similarity 149, member A
chr11_-_59181573 0.66 ENSMUST00000010044.8
wingless-type MMTV integration site family, member 3A
chr14_-_24054186 0.66 ENSMUST00000188991.7
ENSMUST00000224468.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr13_+_34221572 0.66 ENSMUST00000040656.8
biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)
chr6_+_99669640 0.65 ENSMUST00000101122.3
G protein-coupled receptor 27
chr5_+_139529643 0.65 ENSMUST00000174792.2
UNC homeobox
chr17_+_25936463 0.65 ENSMUST00000115108.4
guanine nucleotide binding protein (G protein), gamma 13
chr14_-_24054273 0.62 ENSMUST00000188285.7
ENSMUST00000190044.7
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr13_-_95359955 0.62 ENSMUST00000159608.8
phosphodiesterase 8B
chr2_-_160754212 0.61 ENSMUST00000109454.8
ENSMUST00000057169.5
elastin microfibril interfacer 3
chr12_-_75224099 0.60 ENSMUST00000042299.4
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr11_-_55498559 0.59 ENSMUST00000108853.8
ENSMUST00000075603.5
glycine receptor, alpha 1 subunit
chr8_+_123844090 0.59 ENSMUST00000037900.9
copine VII
chr15_+_99122742 0.57 ENSMUST00000041415.5
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr11_-_101062111 0.57 ENSMUST00000164474.8
ENSMUST00000043397.14
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr4_+_62278932 0.56 ENSMUST00000084526.12
solute carrier family 31, member 1
chr19_+_16416664 0.55 ENSMUST00000237350.2
guanine nucleotide binding protein, alpha 14
chr11_+_108812474 0.55 ENSMUST00000144511.2
axin 2
chr14_-_24053994 0.55 ENSMUST00000225431.2
ENSMUST00000188210.8
ENSMUST00000224787.2
ENSMUST00000225315.2
ENSMUST00000225556.2
ENSMUST00000223727.2
ENSMUST00000223655.2
ENSMUST00000224077.2
ENSMUST00000224812.2
ENSMUST00000224285.2
ENSMUST00000225471.2
ENSMUST00000224232.2
ENSMUST00000223749.2
ENSMUST00000224025.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_+_141470261 0.54 ENSMUST00000203140.2
solute carrier organic anion transporter family, member 1c1
chr11_-_78388560 0.54 ENSMUST00000061174.7
sterile alpha and HEAT/Armadillo motif containing 1
chr5_-_113458563 0.54 ENSMUST00000154248.8
ENSMUST00000112325.8
ENSMUST00000048112.13
small G protein signaling modulator 1
chr15_+_75781584 0.53 ENSMUST00000192937.2
tigger transposable element derived 5
chr14_+_119375753 0.53 ENSMUST00000065904.5
heparan sulfate 6-O-sulfotransferase 3
chr19_+_5497575 0.53 ENSMUST00000025850.7
ENSMUST00000236774.2
fos-like antigen 1
chr4_+_125384481 0.53 ENSMUST00000030676.8
glutamate receptor, ionotropic, kainate 3
chr4_-_108075119 0.52 ENSMUST00000223127.2
ENSMUST00000043793.7
ENSMUST00000106690.9
zyg-11 family member A, cell cycle regulator
chr3_-_63836796 0.52 ENSMUST00000061706.7
RIKEN cDNA E130311K13 gene
chr3_+_54063459 0.51 ENSMUST00000029311.11
ENSMUST00000200048.5
transient receptor potential cation channel, subfamily C, member 4
chr6_+_61157279 0.50 ENSMUST00000126214.8
coiled-coil serine rich 1
chr4_-_24851086 0.49 ENSMUST00000084781.6
ENSMUST00000108218.10
kelch-like 32
chr2_-_166904902 0.49 ENSMUST00000048988.14
zinc finger, NFX1-type containing 1
chr13_-_63721412 0.49 ENSMUST00000195106.2
patched 1
chrX_-_110606766 0.48 ENSMUST00000113422.9
ENSMUST00000038472.7
highly divergent homeobox
chr6_+_141470105 0.48 ENSMUST00000032362.12
ENSMUST00000205214.3
solute carrier organic anion transporter family, member 1c1
chr3_+_133015846 0.48 ENSMUST00000029644.16
ENSMUST00000122334.8
pyrophosphatase (inorganic) 2
chr7_+_49624612 0.47 ENSMUST00000151721.8
ENSMUST00000081872.13
NEL-like 1
chr7_+_28466658 0.47 ENSMUST00000155327.8
sirtuin 2
chr11_+_80191692 0.47 ENSMUST00000017836.8
rhomboid like 3
chr10_+_7465555 0.46 ENSMUST00000134346.8
ENSMUST00000019931.12
ENSMUST00000130590.8
low density lipoprotein receptor-related protein 11
chr4_+_42917228 0.46 ENSMUST00000107976.9
ENSMUST00000069184.9
PHD finger protein 24
chr2_+_164721277 0.46 ENSMUST00000041643.5
phosphorylated CTD interacting factor 1
chr12_-_112893382 0.46 ENSMUST00000075827.5
jagged 2
chr8_-_106863521 0.45 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr19_-_4527475 0.45 ENSMUST00000059295.10
synaptotagmin XII
chr10_+_45211847 0.45 ENSMUST00000095715.5
blood vessel epicardial substance
chr7_+_45522551 0.43 ENSMUST00000211234.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr17_+_35055962 0.43 ENSMUST00000173874.8
ENSMUST00000180043.8
ENSMUST00000046244.15
decapping exoribonuclease
chr1_+_153541020 0.43 ENSMUST00000152114.8
ENSMUST00000111812.8
regulator of G-protein signaling 8
chr4_-_129015493 0.42 ENSMUST00000135763.2
ENSMUST00000149763.3
ENSMUST00000164649.8
hippocalcin
chr5_-_125418107 0.42 ENSMUST00000111390.8
ENSMUST00000086075.13
scavenger receptor class B, member 1
chr9_+_87026337 0.42 ENSMUST00000113149.8
ENSMUST00000049457.14
ENSMUST00000179313.3
melanocortin 2 receptor accessory protein 2
chr17_-_85995680 0.42 ENSMUST00000024947.8
ENSMUST00000163568.4
sine oculis-related homeobox 2
chr5_-_49682150 0.40 ENSMUST00000087395.11
Kv channel interacting protein 4
chr6_-_126621751 0.40 ENSMUST00000055168.5
potassium voltage-gated channel, shaker-related subfamily, member 1
chr6_-_126621770 0.40 ENSMUST00000203094.2
potassium voltage-gated channel, shaker-related subfamily, member 1
chr13_+_55097200 0.40 ENSMUST00000026994.14
ENSMUST00000109994.9
unc-5 netrin receptor A
chr19_-_6285827 0.40 ENSMUST00000025695.10
protein phosphatase 2, regulatory subunit B', beta
chr11_-_70128462 0.39 ENSMUST00000100950.10
RIKEN cDNA 0610010K14 gene
chr15_+_61858883 0.39 ENSMUST00000159338.2
myelocytomatosis oncogene
chr1_-_194859015 0.39 ENSMUST00000082321.9
ENSMUST00000195120.6
complement receptor 2
chr12_-_67269323 0.38 ENSMUST00000037181.16
MAM domain containing glycosylphosphatidylinositol anchor 2
chr15_-_64794139 0.38 ENSMUST00000023007.7
ENSMUST00000228014.2
adenylate cyclase 8
chr5_-_76452365 0.38 ENSMUST00000075159.5
circadian locomotor output cycles kaput
chr10_+_7465845 0.38 ENSMUST00000135907.8
low density lipoprotein receptor-related protein 11
chr9_-_105372330 0.38 ENSMUST00000038118.15
ATPase, Ca++-sequestering
chr17_+_86475205 0.38 ENSMUST00000097275.9
protein kinase C, epsilon
chr19_+_6144449 0.37 ENSMUST00000235513.2
predicted gene 550
chr17_+_37356854 0.37 ENSMUST00000025338.16
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_92990110 0.37 ENSMUST00000107863.4
carbonic anhydrase 10
chr19_+_47167554 0.37 ENSMUST00000235290.2
neuralized E3 ubiquitin protein ligase 1A
chr7_+_6442835 0.36 ENSMUST00000168341.2
olfactory receptor 1344
chr7_-_12514534 0.36 ENSMUST00000211392.2
zinc finger and SCAN domain containing 18
chr14_+_26414422 0.36 ENSMUST00000022433.12
dynein, axonemal, heavy chain 12
chr2_-_180929828 0.35 ENSMUST00000049032.13
glucocorticoid modulatory element binding protein 2
chr10_+_58649181 0.35 ENSMUST00000135526.9
ENSMUST00000153031.2
SH3 domain containing ring finger 3
chr5_-_66308421 0.33 ENSMUST00000200775.4
ENSMUST00000094756.11
RNA binding motif protein 47
chr8_-_33374282 0.33 ENSMUST00000209107.4
ENSMUST00000209022.3
neuregulin 1
chr7_-_67409432 0.33 ENSMUST00000208815.2
ENSMUST00000074233.12
ENSMUST00000208231.2
ENSMUST00000051389.10
synemin, intermediate filament protein
chr8_-_88686188 0.32 ENSMUST00000109655.9
zinc finger protein 423
chr17_+_37357451 0.32 ENSMUST00000172789.2
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_-_49682106 0.32 ENSMUST00000176191.8
Kv channel interacting protein 4
chr16_+_90628001 0.32 ENSMUST00000099543.10
eva-1 homolog C (C. elegans)
chr11_-_55499014 0.32 ENSMUST00000102716.10
glycine receptor, alpha 1 subunit
chr7_-_132725575 0.31 ENSMUST00000171968.8
C-terminal binding protein 2
chr11_-_119910986 0.31 ENSMUST00000134319.2
apoptosis-associated tyrosine kinase
chr8_-_106863423 0.31 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr7_+_97229065 0.30 ENSMUST00000107153.3
remodeling and spacing factor 1
chr4_+_116953218 0.30 ENSMUST00000030443.12
patched 2
chr2_+_164802729 0.29 ENSMUST00000202623.4
solute carrier family 12, member 5
chr2_-_144174066 0.29 ENSMUST00000037423.4
ovo like zinc finger 2
chr10_-_79473675 0.29 ENSMUST00000020564.7
SHC (Src homology 2 domain containing) transforming protein 2
chr7_+_143838191 0.28 ENSMUST00000097929.4
SH3 and multiple ankyrin repeat domains 2
chr1_-_186437760 0.28 ENSMUST00000195201.2
transforming growth factor, beta 2
chr14_-_24054927 0.28 ENSMUST00000145596.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chrX_+_93768175 0.27 ENSMUST00000101388.4
zinc finger, X-linked, duplicated B
chr1_-_194858918 0.27 ENSMUST00000210219.2
ENSMUST00000193801.2
complement receptor 2
chr5_-_142495408 0.26 ENSMUST00000110784.8
Ras association and DIL domains
chr5_+_4242367 0.25 ENSMUST00000177258.2
mitochondrial transcription termination factor 1b
chr8_-_112120442 0.25 ENSMUST00000038475.9
fatty acid 2-hydroxylase
chr4_+_42158092 0.24 ENSMUST00000098122.3
predicted gene 13306
chr5_+_115573055 0.24 ENSMUST00000136586.6
musashi RNA-binding protein 1
chr7_-_46783432 0.24 ENSMUST00000102626.10
protein tyrosine phosphatase, non-receptor type 5
chr1_+_153541412 0.24 ENSMUST00000111814.8
ENSMUST00000111810.2
regulator of G-protein signaling 8
chr2_-_58247764 0.24 ENSMUST00000112608.9
ENSMUST00000112607.3
ENSMUST00000028178.14
activin A receptor, type IC

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0022012 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.7 2.1 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.7 4.2 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.5 3.7 GO:0015862 uridine transport(GO:0015862)
0.5 3.1 GO:0034465 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.5 1.5 GO:0072347 response to anesthetic(GO:0072347)
0.5 1.9 GO:0045914 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.4 4.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.4 1.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 1.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 1.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.4 2.2 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.3 0.9 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.3 2.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 1.2 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.3 1.8 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 2.0 GO:0035106 operant conditioning(GO:0035106)
0.2 1.6 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.2 0.9 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 0.7 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.7 GO:0061184 COP9 signalosome assembly(GO:0010387) negative regulation of cardioblast differentiation(GO:0051892) positive regulation of dermatome development(GO:0061184) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 0.8 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.2 1.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 1.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 3.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 0.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.2 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.2 0.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 0.8 GO:0099558 maintenance of synapse structure(GO:0099558)
0.2 1.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.2 0.5 GO:0040040 thermosensory behavior(GO:0040040)
0.2 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 2.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.6 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 1.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 1.1 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.1 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.7 GO:0061017 hepatoblast differentiation(GO:0061017)
0.1 1.1 GO:0060214 endocardium formation(GO:0060214)
0.1 1.4 GO:0060174 limb bud formation(GO:0060174)
0.1 1.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.4 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.1 0.4 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.4 GO:0046722 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 2.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.3 GO:0070237 endocardial cushion fusion(GO:0003274) positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.1 0.4 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1 0.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.6 GO:0072719 cellular response to cisplatin(GO:0072719) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.3 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.1 GO:0072554 blood vessel lumenization(GO:0072554)
0.1 0.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 2.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.0 0.5 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 2.1 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.8 GO:0015874 norepinephrine transport(GO:0015874)
0.0 1.4 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.8 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.4 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.9 GO:1903859 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 1.7 GO:0035272 exocrine system development(GO:0035272)
0.0 0.1 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.0 0.8 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.3 1.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 2.1 GO:0033010 paranodal junction(GO:0033010)
0.2 1.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 3.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.8 GO:0044301 climbing fiber(GO:0044301)
0.2 0.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 1.1 GO:0097513 myosin II filament(GO:0097513)
0.1 0.8 GO:0071547 piP-body(GO:0071547)
0.1 2.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.8 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.9 2.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.8 0.8 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.6 1.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.6 2.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.5 2.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.4 1.3 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.4 1.6 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 3.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 1.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.3 0.9 GO:0019002 GMP binding(GO:0019002)
0.3 3.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 1.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 1.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.9 GO:0030977 taurine binding(GO:0030977)
0.2 0.9 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 4.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.6 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.1 0.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 2.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 1.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.4 GO:0035276 calcium-independent protein kinase C activity(GO:0004699) ethanol binding(GO:0035276)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.7 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0038100 nodal binding(GO:0038100)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 2.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 2.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 4.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.9 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription