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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for CABZ01066694.1

Z-value: 0.85

Motif logo

Transcription factors associated with CABZ01066694.1

Gene Symbol Gene ID Gene Info
ENSDARG00000110178 ENSDARG00000110178

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CABZ01066694.1dr11_v1_chr6_+_168962_1689620.241.9e-02Click!

Activity profile of CABZ01066694.1 motif

Sorted Z-values of CABZ01066694.1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_5685023 14.44 ENSDART00000148680
ENSDART00000149365
troponin T type 2a (cardiac)
chr12_-_20373058 9.81 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr21_-_25756119 6.60 ENSDART00000002341
claudin c
chr12_+_18524953 5.95 ENSDART00000090332
neuralized E3 ubiquitin protein ligase 2
chr15_+_32711663 5.91 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr3_-_20091964 5.86 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr10_-_17484762 5.19 ENSDART00000137905
ENSDART00000007961
5'-nucleotidase, cytosolic II, like 1
chr20_+_33981946 4.90 ENSDART00000131775
si:dkey-51e6.1
chr18_-_21188768 4.61 ENSDART00000060166
glutamic-oxaloacetic transaminase 2a, mitochondrial
chr7_+_34305903 4.56 ENSDART00000173575
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_-_52417060 4.53 ENSDART00000148579
myocardial zonula adherens protein
chr1_-_23274038 4.31 ENSDART00000181658
replication factor C (activator 1) 1
chr8_+_31872992 4.21 ENSDART00000146933
complement component 7a
chr7_+_12931396 4.08 ENSDART00000184664
ferritin, heavy polypeptide 1a
chr15_-_39969988 4.02 ENSDART00000146054
ribosomal protein S5
chr20_-_26066020 3.82 ENSDART00000078559
myc target 1a
chr18_+_20566817 3.73 ENSDART00000100716
BH3 interacting domain death agonist
chr24_-_39858710 3.72 ENSDART00000134251
solute carrier family 12 (potassium/chloride transporter), member 7b
chr16_-_17300030 3.70 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr8_+_21353878 3.65 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr10_-_22506044 3.61 ENSDART00000100497
zgc:172339
chr6_-_49078263 3.44 ENSDART00000032982
solute carrier family 5 (iodide transporter), member 8-like
chr11_-_45185792 3.35 ENSDART00000171328
si:dkey-93h22.7
chr19_+_48102560 3.32 ENSDART00000164464
UTP18 small subunit (SSU) processome component
chr19_+_37509638 3.30 ENSDART00000139999
si:ch211-250g4.3
chr9_+_41156287 3.14 ENSDART00000189195
ENSDART00000186270
signal transducer and activator of transcription 4
chr21_+_198269 3.13 ENSDART00000193485
ENSDART00000163696
gonadal somatic cell derived factor
chr18_+_33340868 3.10 ENSDART00000099139
vomeronasal 2 receptor, h14
chr19_-_27578929 3.09 ENSDART00000177368
si:dkeyp-46h3.3
chr6_+_41038757 2.94 ENSDART00000011245
ectonucleoside triphosphate diphosphohydrolase 8
chr9_+_41156818 2.92 ENSDART00000105764
ENSDART00000147052
signal transducer and activator of transcription 4
chr1_+_25585 2.91 ENSDART00000161139

chr15_-_28587147 2.87 ENSDART00000156049
slingshot protein phosphatase 2a
chr6_-_3982783 2.85 ENSDART00000171944
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr25_-_32311048 2.81 ENSDART00000181806
ENSDART00000086334

chr15_+_404891 2.76 ENSDART00000155682
nipsnap homolog 2
chr17_+_8175998 2.65 ENSDART00000131200
myc target 1b
chr24_-_39121900 2.63 ENSDART00000020282

chr3_-_11203689 2.57 ENSDART00000166328

chr5_+_9246458 2.56 ENSDART00000081772
sushi domain containing 1
chr1_+_54655160 2.55 ENSDART00000190319
si:ch211-202h22.7
chr9_-_7652792 2.54 ENSDART00000137957
DnaJ (Hsp40) homolog, subfamily B, member 2
chr4_+_76692834 2.46 ENSDART00000064315
ENSDART00000137653
membrane-spanning 4-domains, subfamily A, member 17A.1
chr2_-_42375275 2.42 ENSDART00000026339
GTP binding protein 4
chr3_-_3428938 2.32 ENSDART00000179811
ENSDART00000115282
ENSDART00000192263
ENSDART00000046454
zgc:171445
chr21_-_11834452 2.28 ENSDART00000081652
Rieske (Fe-S) domain containing
chr23_+_4689626 2.23 ENSDART00000131532
glycoprotein IX (platelet)
chr9_-_42871756 2.22 ENSDART00000191396
titin, tandem duplicate 1
chr25_-_13320986 2.22 ENSDART00000169238
si:ch211-194m7.8
chr6_+_3334710 2.21 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr3_-_34074806 2.08 ENSDART00000151415
immunoglobulin heavy variable 8-1
chr10_+_36345176 2.06 ENSDART00000099397
odorant receptor, family C, subfamily 105, member 1
chr5_+_9246018 2.04 ENSDART00000081769
ENSDART00000183189
sushi domain containing 1
chr10_+_40633990 2.03 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
chr3_-_3413669 2.03 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
chr15_-_9294929 1.98 ENSDART00000155717
si:ch211-261a10.5
chr3_-_1387292 1.97 ENSDART00000163535
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr3_+_32577994 1.89 ENSDART00000180643
si:ch73-248e21.1
chr5_-_7829657 1.88 ENSDART00000158374
PDZ and LIM domain 5a
chr10_-_32558917 1.86 ENSDART00000128888
ENSDART00000143301
monoacylglycerol O-acyltransferase 2
chr1_+_9082417 1.84 ENSDART00000146303
calcium channel, voltage-dependent, gamma subunit 3a
chr6_+_3334392 1.82 ENSDART00000133707
ENSDART00000130879
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr7_+_5052336 1.81 ENSDART00000133393
si:ch211-272h9.6
chr5_+_30520249 1.80 ENSDART00000013431
hydroxymethylbilane synthase a
chr7_-_38638809 1.78 ENSDART00000144341
six-cysteine containing astacin protease 4
chr25_+_13321307 1.76 ENSDART00000161284
si:ch211-194m7.5
chr15_+_17621375 1.73 ENSDART00000158352
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr12_-_23658888 1.72 ENSDART00000088319
mitogen-activated protein kinase kinase kinase 8
chr16_+_54829574 1.72 ENSDART00000148392
poly(A) binding protein, cytoplasmic 1a
chr7_+_19502744 1.71 ENSDART00000171258
ENSDART00000173691
si:ch211-212k18.9
chr21_-_44565236 1.65 ENSDART00000159323
fun14 domain containing 2
chr23_-_24488696 1.65 ENSDART00000155593
transmembrane protein 82
chr10_+_41199660 1.65 ENSDART00000125314
adrenoceptor beta 3b
chr2_-_32768951 1.64 ENSDART00000004712
beaded filament structural protein 2, phakinin
chr8_-_4586696 1.64 ENSDART00000143511
ENSDART00000134324
glycoprotein Ib (platelet), beta polypeptide
chr19_-_27564458 1.63 ENSDART00000123155
si:dkeyp-46h3.6
chr18_+_33550667 1.61 ENSDART00000141246
ENSDART00000136070
si:dkey-47k20.1
chr3_-_31019715 1.60 ENSDART00000156687
ENSDART00000156127
ENSDART00000153945
si:dkeyp-71f10.5
chr1_+_2025085 1.59 ENSDART00000008332
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3a
chr23_+_22658700 1.59 ENSDART00000192248
enolase 1a, (alpha)
chr24_-_39683582 1.56 ENSDART00000056386

chr15_+_9294620 1.50 ENSDART00000133588
ENSDART00000140009
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr1_-_6028876 1.48 ENSDART00000168117
si:ch1073-345a8.1
chr15_+_36054864 1.47 ENSDART00000156697
collagen, type IV, alpha 3
chr16_-_24668620 1.47 ENSDART00000012807
paraoxonase 3, tandem duplicate 2
chr15_-_37719015 1.46 ENSDART00000154875
si:dkey-117a8.1
chr2_-_35103069 1.45 ENSDART00000111730
pappalysin 2
chr3_-_7961226 1.45 ENSDART00000159801
tripartite motif containing 35-23
chr25_+_12849609 1.43 ENSDART00000168144
chemokine (C-C motif) ligand 33, duplicate 2
chr10_-_24753715 1.42 ENSDART00000192401
integrin-linked kinase
chr17_+_23994633 1.40 ENSDART00000156988
si:ch211-63b16.3
chr17_-_50301313 1.37 ENSDART00000125772
si:ch73-50f9.4
chr19_-_10920577 1.36 ENSDART00000165630
extracellular matrix protein 1a
chr4_-_11122638 1.36 ENSDART00000150600
si:dkey-21h14.10
chr20_-_1439256 1.36 ENSDART00000002928
thymocyte selection associated
chr25_+_35062353 1.35 ENSDART00000089844
zgc:113983
chr5_-_68244564 1.30 ENSDART00000169350

chr2_+_47927026 1.30 ENSDART00000143023
finTRIM family, member 25
chr6_+_28877306 1.28 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tumor protein p63
chr19_+_47502581 1.27 ENSDART00000171526

chr7_+_8324506 1.26 ENSDART00000168110
si:dkey-185m8.2
chr1_+_58400409 1.25 ENSDART00000111526
si:ch73-59p9.2
chr20_-_31018569 1.24 ENSDART00000136039
fibronectin type III domain containing 1
chr15_+_35253247 1.24 ENSDART00000066737
zgc:158328
chr2_+_49713592 1.23 ENSDART00000189624

chr7_-_3826639 1.23 ENSDART00000060330
si:dkey-88n24.10
chr2_+_16160906 1.22 ENSDART00000135783
selenoprotein J
chr22_+_2680895 1.19 ENSDART00000082245
zgc:194221
chr24_+_42129775 1.17 ENSDART00000181576
WW domain containing E3 ubiquitin protein ligase 1
chr4_-_11132617 1.15 ENSDART00000150250
si:dkey-21h14.9
chr25_+_2415131 1.12 ENSDART00000162210
zmp:0000000932
chr22_+_9981079 1.12 ENSDART00000124236

chr3_-_58205045 1.12 ENSDART00000130740
si:ch211-256e16.11
chr17_-_31360951 1.10 ENSDART00000062894
ENSDART00000134686
isovaleryl-CoA dehydrogenase
chr7_-_3826794 1.10 ENSDART00000064229
ENSDART00000142138
si:dkey-88n24.10
chr3_+_59411956 1.09 ENSDART00000166982
SEC14-like lipid binding 1
chr23_-_17450746 1.07 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tumor protein D52-like 2b
chr13_+_33651416 1.05 ENSDART00000180221

chr13_+_30169681 1.04 ENSDART00000138326
phosphatase domain containing, paladin 1b
chr25_-_16742438 1.03 ENSDART00000156091
polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 1
chr20_+_35445462 1.02 ENSDART00000124497
tudor domain containing 6
chr4_+_59245846 1.01 ENSDART00000104921
si:dkey-105i14.1
chr7_-_16597130 1.00 ENSDART00000144118
E2F transcription factor 8
chr1_+_49510209 0.98 ENSDART00000052998
si:dkeyp-80c12.4
chr4_-_11106856 0.98 ENSDART00000150764

chr22_+_6254194 0.98 ENSDART00000112388
ENSDART00000135176
ribonuclease like 4
chr16_-_10547781 0.97 ENSDART00000166495
g6f-like
chr12_+_33433882 0.97 ENSDART00000185053
fatty acid synthase
chr22_+_7923713 0.94 ENSDART00000167210

chr19_+_40250682 0.89 ENSDART00000102888
cyclin-dependent kinase 6
chr7_-_17591007 0.89 ENSDART00000171023

chr5_-_7897316 0.86 ENSDART00000160743
ENSDART00000160912
opsin 4xb
chr25_-_26018240 0.85 ENSDART00000150800
acyl-CoA synthetase bubblegum family member 1
chr20_+_6590220 0.85 ENSDART00000136567
tensin 3, tandem duplicate 2
chr20_-_12936861 0.83 ENSDART00000141046
si:dkey-54g2.2
chr21_-_40040178 0.83 ENSDART00000159741
Danio rerio multidrug and toxin extrusion protein 1-like (mate4), mRNA.
chr23_+_28377360 0.80 ENSDART00000014983
ENSDART00000128831
ENSDART00000135178
ENSDART00000138621
zgc:153867
chr9_+_52613820 0.80 ENSDART00000168753
ENSDART00000165580
ENSDART00000164769
si:ch211-241j8.2
chr9_-_2936017 0.79 ENSDART00000102823
sterile alpha motif and leucine zipper containing kinase AZK
chr13_-_23031803 0.77 ENSDART00000056523
hexokinase domain containing 1
chr7_+_9922607 0.77 ENSDART00000184532
ENSDART00000113396
ceramide synthase 3a
chr25_-_26018424 0.76 ENSDART00000089332
acyl-CoA synthetase bubblegum family member 1
chr3_-_26183699 0.75 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
chr24_-_41195068 0.73 ENSDART00000121592
activin A receptor type 2Ba
chr18_+_618005 0.72 ENSDART00000189667
protogenin homolog a (Gallus gallus)
chr3_-_5555500 0.72 ENSDART00000176133
ENSDART00000057464
tripartite motif containing 35-31
chr20_-_22378401 0.72 ENSDART00000011135
ENSDART00000110967
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr24_+_7153628 0.71 ENSDART00000147715
si:dkeyp-101e12.1
chr4_+_37936249 0.70 ENSDART00000184022
si:dkeyp-82b4.2
chr12_+_15078124 0.68 ENSDART00000187571

chr2_-_43850637 0.67 ENSDART00000136077
zinc finger E-box binding homeobox 1a
chr13_-_32726178 0.67 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr15_+_45563656 0.64 ENSDART00000157501
claudin 15-like b
chr25_+_7299488 0.63 ENSDART00000184836
high mobility group 20A
chr2_+_8779164 0.62 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr3_-_7940522 0.60 ENSDART00000159710
ENSDART00000167201
tripartite motif containing 35-25
chr5_+_43782267 0.58 ENSDART00000130355
nitric oxide synthase 2a, inducible
chr24_+_18286427 0.57 ENSDART00000055443
thiamin pyrophosphokinase 1
chr2_+_21486529 0.57 ENSDART00000047468
inhibin, beta Ab
chr16_-_30931651 0.57 ENSDART00000132643
solute carrier family 45, member 4
chr8_-_45729248 0.55 ENSDART00000187736

chr16_-_42303856 0.53 ENSDART00000180030
protoporphyrinogen oxidase
chr14_+_9462726 0.52 ENSDART00000063559
RELT-like 2
chr16_+_54829293 0.52 ENSDART00000024729
poly(A) binding protein, cytoplasmic 1a
chr25_+_6186823 0.50 ENSDART00000153526
ornithine decarboxylase antizyme 2a
chr25_-_12805295 0.49 ENSDART00000157629
carbonic anhydrase Va
chr3_+_28502419 0.48 ENSDART00000151081
septin 12
chr14_+_34514336 0.47 ENSDART00000024440
forkhead box I3b
chr8_+_8947623 0.42 ENSDART00000131215
solute carrier family 35 (UDP-galactose transporter), member 2
chr5_+_67971627 0.41 ENSDART00000144879
mitochondrial translational initiation factor 3
chr23_+_12072980 0.39 ENSDART00000141646
endothelin 3b
chr23_+_25856541 0.36 ENSDART00000145426
ENSDART00000028236
hepatocyte nuclear factor 4, alpha
chr14_+_46268248 0.36 ENSDART00000172979
calcium binding protein 2b
chr13_-_5065539 0.35 ENSDART00000141790
ATP-binding cassette, sub-family G (WHITE), member 2c
chr13_+_42011287 0.34 ENSDART00000131147
cytochrome P450, family 1, subfamily B, polypeptide 1
chr15_-_23522653 0.33 ENSDART00000144685
hydroxymethylbilane synthase, b
chr1_+_24557414 0.33 ENSDART00000076519
dCTP pyrophosphatase 1
chr4_-_75681004 0.32 ENSDART00000186296
si:dkey-71l4.5
chr21_-_22648007 0.29 ENSDART00000121788
grass carp reovirus (GCRV)-induced gene 2l
chr3_+_52737565 0.29 ENSDART00000108639
GEM interacting protein
chr12_+_48674381 0.28 ENSDART00000105309
uroporphyrinogen III synthase
chr16_+_45930962 0.28 ENSDART00000124689
ENSDART00000041811
OTU deubiquitinase 7B
chr17_-_23609210 0.27 ENSDART00000064003
interferon-induced protein with tetratricopeptide repeats 15
chr5_-_69523816 0.20 ENSDART00000112692
si:ch211-157p22.10
chr10_-_10969596 0.17 ENSDART00000092011
exonuclease 3'-5' domain containing 3
chr4_-_1839192 0.15 ENSDART00000003790
PWP1 homolog (S. cerevisiae)
chr22_-_30935510 0.15 ENSDART00000133335
si:dkey-49n23.1
chr16_-_30931468 0.08 ENSDART00000187838
solute carrier family 45, member 4
chr11_+_41981959 0.04 ENSDART00000055707
hairy and enhancer of split-related 15, tandem duplicate 1
chr7_+_1467863 0.00 ENSDART00000173433
ER membrane protein complex subunit 4

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01066694.1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.4 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
1.6 4.9 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
1.2 4.6 GO:0006531 aspartate metabolic process(GO:0006531)
0.9 3.7 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.7 4.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.6 4.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 1.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.5 1.4 GO:0043383 negative T cell selection(GO:0043383)
0.4 6.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.4 7.3 GO:0016203 muscle attachment(GO:0016203)
0.3 1.6 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.3 2.8 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.3 5.9 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.0 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 1.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.6 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.2 0.7 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 4.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 2.9 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 1.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.2 1.1 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.3 GO:0031179 peptide modification(GO:0031179)
0.1 4.2 GO:0019835 cytolysis(GO:0019835)
0.1 2.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 3.1 GO:0001556 oocyte maturation(GO:0001556)
0.1 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 6.1 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.1 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.8 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.3 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 1.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.9 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.4 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263) regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.0 GO:0030719 P granule organization(GO:0030719)
0.1 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.6 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 5.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.1 0.8 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 1.4 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 1.0 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 1.9 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0 1.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 1.0 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 2.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 1.6 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 1.4 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.7 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.7 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 3.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 2.9 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.4 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 3.7 GO:0016485 protein processing(GO:0016485)
0.0 0.5 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.6 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 4.5 GO:0060047 heart contraction(GO:0060047)
0.0 2.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.5 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 1.5 GO:0048545 response to steroid hormone(GO:0048545)
0.0 2.9 GO:0006814 sodium ion transport(GO:0006814)
0.0 9.9 GO:0016567 protein ubiquitination(GO:0016567)
0.0 3.4 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 2.2 GO:0006417 regulation of translation(GO:0006417)
0.0 3.3 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 1.0 GO:0033391 chromatoid body(GO:0033391)
0.3 14.4 GO:0005861 troponin complex(GO:0005861)
0.3 4.2 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.8 GO:0000801 central element(GO:0000801)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 4.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 5.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 8.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 2.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 4.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.3 14.4 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
1.2 4.9 GO:0101006 protein histidine phosphatase activity(GO:0101006)
1.2 3.6 GO:0016748 succinyltransferase activity(GO:0016748)
1.2 4.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
1.1 9.8 GO:0015250 water channel activity(GO:0015250)
0.7 2.9 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.6 4.0 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.4 1.6 GO:0051380 norepinephrine binding(GO:0051380)
0.4 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.4 2.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.3 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 4.1 GO:0008199 ferric iron binding(GO:0008199)
0.3 5.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 1.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 5.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 2.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.6 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.2 2.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 2.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.6 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.9 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.4 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 4.0 GO:0019843 rRNA binding(GO:0019843)
0.1 2.0 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.9 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.5 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 1.0 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 2.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 6.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 9.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 4.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 2.7 GO:0008083 growth factor activity(GO:0008083)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 1.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 4.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 4.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 4.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 4.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors