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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for CR354582.1

Z-value: 0.72

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Transcription factors associated with CR354582.1

Gene Symbol Gene ID Gene Info
ENSDARG00000110598 ENSDARG00000110598

Activity profile of CR354582.1 motif

Sorted Z-values of CR354582.1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 11.61 ENSDART00000021620
claudin d
chr12_-_35830625 11.43 ENSDART00000180028

chr9_-_35633827 11.19 ENSDART00000077745
zona pellucida glycoprotein 2, like 1
chr2_-_15324837 10.91 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr20_-_23426339 10.58 ENSDART00000004625
zygote arrest 1
chr23_+_20110086 8.52 ENSDART00000054664
troponin C type 1b (slow)
chr21_-_5205617 8.45 ENSDART00000145554
ENSDART00000045284
ribosomal protein L37
chr3_+_18398876 7.90 ENSDART00000141100
ENSDART00000138107
ribosomal protein S2
chr10_-_21362320 7.76 ENSDART00000189789
avidin
chr10_-_21362071 7.52 ENSDART00000125167
avidin
chr15_-_23376541 7.21 ENSDART00000078570
C1q and TNF related 5
chr20_-_40755614 7.02 ENSDART00000061247
connexin 32.3
chr24_+_38306010 6.74 ENSDART00000143184
myosin binding protein C, fast type b
chr6_-_7720332 6.45 ENSDART00000135945
ribosomal protein SA
chr12_+_22580579 6.31 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr24_-_37640705 6.06 ENSDART00000066583
zgc:112496
chr16_-_42056137 5.81 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr6_+_41191482 5.35 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr10_-_34002185 5.34 ENSDART00000046599
zygote arrest 1-like
chr2_+_6253246 5.31 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr11_+_18183220 5.30 ENSDART00000113468

chr19_-_13808630 5.09 ENSDART00000166895
ENSDART00000187670
connective tissue growth factor b
chr8_-_23780334 5.01 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr6_+_49926115 4.88 ENSDART00000018523
adenosylhomocysteinase
chr23_+_44374041 4.86 ENSDART00000136056
eph receptor B4b
chr10_-_2971407 4.60 ENSDART00000132526
MARVEL domain containing 2a
chr18_+_9171778 4.45 ENSDART00000101192
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr24_+_19415124 4.42 ENSDART00000186931
sulfatase 1
chr21_-_35419486 4.27 ENSDART00000138529
si:dkeyp-23e4.3
chr15_-_47848544 4.23 ENSDART00000098711
eukaryotic translation initiation factor 3, subunit K
chr10_+_21867307 4.14 ENSDART00000126629
cerebellin 17
chr21_+_11244068 4.13 ENSDART00000163432
AT-rich interaction domain 6
chr17_+_16046132 4.12 ENSDART00000155005
si:ch73-204p21.2
chr22_-_10121880 4.09 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr11_-_6048490 4.03 ENSDART00000066164
plasmalemma vesicle associated protein b
chr18_+_48423973 4.03 ENSDART00000184233
ENSDART00000147074
Fli-1 proto-oncogene, ETS transcription factor a
chr8_-_24252933 4.03 ENSDART00000057624
zgc:110353
chr17_+_16046314 3.95 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
chr13_-_31017960 3.93 ENSDART00000145287
WDFY family member 4
chr12_-_48477031 3.91 ENSDART00000105176
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr10_+_6884627 3.89 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr8_+_11425048 3.88 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr5_-_63302944 3.80 ENSDART00000047110
gelsolin b
chr9_+_50001746 3.68 ENSDART00000058892
solute carrier family 38, member 11
chr19_+_31585917 3.67 ENSDART00000132182
geminin, DNA replication inhibitor
chr11_+_24703108 3.57 ENSDART00000159173
G protein-coupled receptor 25
chr22_-_10586191 3.56 ENSDART00000148418
si:dkey-42i9.16
chr4_-_9891874 3.48 ENSDART00000067193
adrenomedullin 2a
chr17_+_8799451 3.40 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr12_+_20352400 3.39 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr24_+_1023839 3.39 ENSDART00000082526
zgc:111976
chr12_-_14143344 3.34 ENSDART00000152742
bucky ball 2-like
chr19_-_657439 3.27 ENSDART00000167100
solute carrier family 6 (neutral amino acid transporter), member 18
chr10_-_35257458 3.18 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr3_+_17537352 3.15 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr24_-_25144441 3.14 ENSDART00000152104
pleckstrin homology-like domain, family B, member 2b
chr11_-_30634286 3.10 ENSDART00000191019
zgc:153665
chr24_-_34680956 3.08 ENSDART00000171009
catenin (cadherin-associated protein), alpha 1
chr13_+_35637048 3.05 ENSDART00000085037
thrombospondin 2a
chr23_-_24394719 3.04 ENSDART00000044918
eph receptor A2 b
chr8_+_45334255 3.03 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr22_+_20427170 3.00 ENSDART00000136744
forkhead box Q2
chr16_-_22930925 2.98 ENSDART00000133819
si:dkey-246i14.3
chr24_+_37640626 2.98 ENSDART00000008047
WD repeat domain 24
chr1_-_18811517 2.97 ENSDART00000142026
si:dkey-167i21.2
chr11_-_1550709 2.97 ENSDART00000110097
si:ch73-303b9.1
chr9_-_19161982 2.94 ENSDART00000081878
POU class 1 homeobox 1
chr10_+_39212898 2.94 ENSDART00000159501
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr3_+_17933553 2.93 ENSDART00000167731
ENSDART00000165644
2',3'-cyclic nucleotide 3' phosphodiesterase
chr18_+_20560442 2.91 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr4_+_11464255 2.83 ENSDART00000008584
GDP dissociation inhibitor 2
chr23_+_2728095 2.81 ENSDART00000066086
zgc:114123
chr14_+_45471642 2.80 ENSDART00000126979
ENSDART00000172952
ENSDART00000173284
UBX domain protein 1
chr14_+_33329761 2.78 ENSDART00000161138
sosondowah ankyrin repeat domain family d
chr8_-_14126646 2.70 ENSDART00000027225
biglycan a
chr18_-_40708537 2.69 ENSDART00000077577
si:ch211-132b12.8
chr12_+_48803098 2.62 ENSDART00000074768
peptidylprolyl isomerase Fb
chr19_+_43297546 2.62 ENSDART00000168002
lysosomal protein transmembrane 5
chr22_+_19407531 2.56 ENSDART00000141060
si:dkey-78l4.2
chr9_-_50001606 2.56 ENSDART00000161648
ENSDART00000168514
sodium channel, voltage-gated, type I, alpha
chr6_+_102506 2.56 ENSDART00000172678
low density lipoprotein receptor b
chr3_+_13624815 2.55 ENSDART00000161451
peptidoglycan recognition protein 6
chr9_-_22057658 2.53 ENSDART00000101944
crystallin, gamma MX, like 1
chr25_-_13703826 2.51 ENSDART00000163398
phospholipase A2, group XV
chr1_-_55248496 2.47 ENSDART00000098615
nanos homolog 3
chr8_+_20776654 2.41 ENSDART00000135850
nuclear factor I/C
chr5_-_9625459 2.40 ENSDART00000143347
SH2B adaptor protein 3
chr4_-_4387012 2.38 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr25_-_6049339 2.36 ENSDART00000075184
sorting nexin 1a
chr22_-_13350240 2.35 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
chr24_-_2450597 2.33 ENSDART00000188080
ENSDART00000093331
ras responsive element binding protein 1a
chr10_-_13343831 2.31 ENSDART00000135941
interleukin 11 receptor, alpha
chr10_+_6884123 2.27 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_-_23643751 2.26 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr17_-_10122204 2.21 ENSDART00000160751

chr19_+_390298 2.21 ENSDART00000136361
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr11_-_45138857 2.21 ENSDART00000166501
calcium activated nucleotidase 1b
chr7_+_34592526 2.19 ENSDART00000173959
formin homology 2 domain containing 1
chr24_+_6107901 2.16 ENSDART00000156419
si:ch211-37e10.2
chr15_+_31344472 2.16 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr14_+_33329420 2.16 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr10_+_36178713 2.16 ENSDART00000140816
odorant receptor, family D, subfamily 108, member 3
chr6_+_50381665 2.14 ENSDART00000141128
cytochrome c-1
chr5_+_6954162 2.09 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr10_-_11385155 2.09 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr24_+_13316737 2.07 ENSDART00000191658
somatomedin B and thrombospondin type 1 domain containing
chr7_+_2236317 2.05 ENSDART00000075859
zgc:172065
chr2_+_8779164 2.04 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr2_+_39021282 2.04 ENSDART00000056577
si:ch211-119o8.7
chr25_-_10503043 2.01 ENSDART00000155404
cytochrome c oxidase subunit 8b
chr25_+_35891342 1.95 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr23_-_17003533 1.95 ENSDART00000080545
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr8_-_12867128 1.92 ENSDART00000142201
solute carrier family 2 (facilitated glucose transporter), member 6
chr16_+_33902006 1.88 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)
chr5_-_15851953 1.88 ENSDART00000173101
si:dkey-1k23.3
chr11_+_31864921 1.88 ENSDART00000180252
diaphanous-related formin 3
chr10_+_25726694 1.86 ENSDART00000140308
UDP glucuronosyltransferase 5 family, polypeptide D1
chr20_+_37294112 1.85 ENSDART00000076293
ENSDART00000140450
connexin 23
chr6_+_52873822 1.85 ENSDART00000103138
odorant receptor, family H, subfamily 137, member 3
chr16_-_16761164 1.79 ENSDART00000135872
si:dkey-27n14.1
chr7_-_51368681 1.78 ENSDART00000146385
Rho GTPase activating protein 36
chr9_+_22364997 1.77 ENSDART00000188054
ENSDART00000046116
crystallin, gamma S3
chr10_+_35257651 1.76 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr12_+_16168342 1.73 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr14_+_40874608 1.73 ENSDART00000168448
si:ch211-106m9.1
chr22_+_28337429 1.71 ENSDART00000166177
interphotoreceptor matrix proteoglycan 2b
chr7_-_23768234 1.70 ENSDART00000173981
si:ch211-200p22.4
chr19_-_5265155 1.70 ENSDART00000145003
perforin 1.3
chr10_+_39212601 1.67 ENSDART00000168778
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr20_-_37813863 1.66 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr12_+_10631266 1.64 ENSDART00000161455
colony stimulating factor 3 (granulocyte) a
chr13_+_38817871 1.63 ENSDART00000187708
collagen, type XIX, alpha 1
chr18_+_2228737 1.61 ENSDART00000165301
RAB27A, member RAS oncogene family
chr6_+_28208973 1.61 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
si:ch73-14h10.2
chr13_+_38814521 1.61 ENSDART00000110976
collagen, type XIX, alpha 1
chr4_+_13586689 1.58 ENSDART00000067161
ENSDART00000138201
transportin 3
chr21_-_22827548 1.56 ENSDART00000079161
angiopoietin-like 5
chr13_+_35339182 1.56 ENSDART00000019323
jagged 1b
chr12_-_33357655 1.54 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr10_-_40421050 1.50 ENSDART00000141834
ENSDART00000164847
trace amine associated receptor 20w
chr9_-_3934963 1.49 ENSDART00000062336
ubiquitin protein ligase E3 component n-recognin 3
chr18_-_15551360 1.48 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr10_+_40660772 1.46 ENSDART00000148007
trace amine associated receptor 19l
chr14_+_34490445 1.46 ENSDART00000132193
ENSDART00000148044
wingless-type MMTV integration site family, member 8a
chr15_-_2493771 1.45 ENSDART00000184906
sialidase 4
chr13_+_255067 1.44 ENSDART00000102505
forkhead box G1d
chr24_-_16899406 1.44 ENSDART00000148753
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr1_-_29139141 1.44 ENSDART00000075546
ENSDART00000133246
heat shock transcription factor 2 binding protein
chr7_-_7764287 1.44 ENSDART00000173021
ENSDART00000113131
inturned planar cell polarity protein
chr19_+_10339538 1.43 ENSDART00000151808
ENSDART00000151235
recoverin 3
chr2_+_20793982 1.43 ENSDART00000014785
proteoglycan 4a
chr21_-_26490186 1.40 ENSDART00000009889
zgc:110540
chr2_-_23778180 1.39 ENSDART00000136782
si:dkey-24c2.7
chr3_-_50443607 1.38 ENSDART00000074036
recoverin a
chr13_+_27232848 1.38 ENSDART00000138043
Ras and Rab interactor 2
chr4_-_20292821 1.35 ENSDART00000136069
ENSDART00000192504
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr4_-_56954002 1.31 ENSDART00000160934
si:dkey-269o24.1
chr1_-_17715493 1.31 ENSDART00000133027
si:dkey-256e7.8
chr8_-_15129573 1.30 ENSDART00000142358
BCAR3, NSP family adaptor protein
chr15_+_47903864 1.25 ENSDART00000063835
orthodenticle homolog 5
chr18_-_25646286 1.24 ENSDART00000099511
ENSDART00000186890
si:ch211-13k12.2
chr4_-_9852318 1.22 ENSDART00000080702
glycosyltransferase 8 domain containing 2
chr3_+_17933132 1.21 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_-_19007834 1.21 ENSDART00000153248
chondroadherin-like b
chr20_-_9095105 1.20 ENSDART00000140792
OMA1 zinc metallopeptidase
chr4_+_306036 1.20 ENSDART00000103659
mesogenin 1
chr3_+_46635527 1.20 ENSDART00000153971
si:dkey-248g21.1
chr10_+_42423318 1.19 ENSDART00000134282
neuropeptide Y receptor Y8a
chr9_+_41156818 1.18 ENSDART00000105764
ENSDART00000147052
signal transducer and activator of transcription 4
chr17_-_23616626 1.17 ENSDART00000104730
interferon-induced protein with tetratricopeptide repeats 14
chr16_-_17347727 1.16 ENSDART00000144392
zyxin
chr11_-_3865472 1.16 ENSDART00000161426
GATA binding protein 2a
chr21_+_15592426 1.15 ENSDART00000138207
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr11_-_44801968 1.15 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr18_+_1837668 1.14 ENSDART00000164210

chr8_+_25034544 1.12 ENSDART00000123300
neugrin, neurite outgrowth associated
chr23_-_19230627 1.11 ENSDART00000007122
guanylate cyclase activator 1B
chr6_+_3280939 1.11 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr17_+_37227936 1.08 ENSDART00000076009
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr18_+_2554666 1.08 ENSDART00000167218
purinergic receptor P2Y2, tandem duplicate 1
chr22_+_28337204 1.07 ENSDART00000163352
interphotoreceptor matrix proteoglycan 2b
chr21_-_17296789 1.06 ENSDART00000192180
growth factor independent 1B transcription repressor
chr11_-_15296805 1.05 ENSDART00000124968
ribophorin II
chr7_+_48667081 1.03 ENSDART00000083473
transient receptor potential cation channel, subfamily M, member 5
chr22_-_5518117 1.01 ENSDART00000164613

chr10_+_2799285 0.99 ENSDART00000030709
posterior neuron-specific homeobox
chr15_+_34988148 0.99 ENSDART00000076269
coiled-coil domain containing 105
chr18_-_25568994 0.99 ENSDART00000133029
si:ch211-13k12.2
chr24_-_35282568 0.98 ENSDART00000167406
ENSDART00000088609
syntrophin, gamma 1
chr4_-_71912457 0.96 ENSDART00000179685
si:dkey-92c21.1
chr5_-_25733745 0.94 ENSDART00000051566
zgc:101016
chr1_-_5455498 0.94 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr15_+_1796313 0.92 ENSDART00000126253
family with sequence similarity 124B
chr10_-_26512993 0.89 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
chr16_+_42471455 0.88 ENSDART00000166640
si:ch211-215k15.5
chr15_+_36309070 0.88 ENSDART00000157034
geminin coiled-coil domain containing
chr6_+_50381347 0.85 ENSDART00000055504
cytochrome c-1
chr7_+_19495379 0.85 ENSDART00000180514
si:ch211-212k18.8
chr10_-_32494499 0.85 ENSDART00000129395
UV radiation resistance associated gene
chr10_+_17714866 0.85 ENSDART00000039969
solute carrier family 20 (phosphate transporter), member 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of CR354582.1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.1 3.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
1.0 2.9 GO:0060631 regulation of meiosis I(GO:0060631)
0.9 4.4 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.9 2.6 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.8 4.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.8 3.1 GO:0042755 eating behavior(GO:0042755)
0.7 4.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.7 11.1 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.6 2.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.6 4.4 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.5 1.5 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.5 1.9 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.5 8.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.4 1.8 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 1.2 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.4 2.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 1.9 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.4 1.2 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.4 1.2 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.4 6.2 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.4 2.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.3 11.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.3 3.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 1.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 8.7 GO:0051014 actin filament severing(GO:0051014)
0.3 6.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 1.1 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.3 4.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.3 2.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 2.6 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.2 4.0 GO:0043114 regulation of vascular permeability(GO:0043114)
0.2 3.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 2.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 4.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 3.4 GO:0031297 replication fork processing(GO:0031297)
0.2 3.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 8.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 2.8 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.2 4.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 3.4 GO:0015671 oxygen transport(GO:0015671)
0.2 4.1 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 1.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 2.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 11.3 GO:0017148 negative regulation of translation(GO:0017148)
0.1 3.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.3 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 1.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.3 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 4.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 3.1 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 1.6 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.1 2.0 GO:0043967 histone H4 acetylation(GO:0043967)
0.1 3.2 GO:0007050 cell cycle arrest(GO:0007050)
0.1 3.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.7 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 1.4 GO:0060173 limb development(GO:0060173)
0.1 1.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.7 GO:0019835 cytolysis(GO:0019835)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 4.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 2.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 4.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 3.1 GO:0001894 tissue homeostasis(GO:0001894)
0.0 4.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 4.6 GO:0001756 somitogenesis(GO:0001756)
0.0 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.6 GO:0030217 T cell differentiation(GO:0030217)
0.0 12.5 GO:0006412 translation(GO:0006412)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 2.9 GO:0001708 cell fate specification(GO:0001708)
0.0 0.7 GO:0051784 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 1.2 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 3.1 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 2.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 2.4 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 2.4 GO:0006260 DNA replication(GO:0006260)
0.0 1.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.2 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.2 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 3.6 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.0 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.0 2.8 GO:0060537 muscle tissue development(GO:0060537)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0061689 tricellular tight junction(GO:0061689)
0.6 2.8 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.5 1.5 GO:0097189 apoptotic body(GO:0097189)
0.5 3.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 3.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 14.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 3.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 8.6 GO:0043186 P granule(GO:0043186)
0.2 2.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.4 GO:0030904 retromer complex(GO:0030904)
0.2 8.5 GO:0005861 troponin complex(GO:0005861)
0.2 4.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.2 3.1 GO:0030057 desmosome(GO:0030057)
0.2 8.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.2 1.7 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.2 GO:0035060 brahma complex(GO:0035060)
0.1 3.1 GO:0045180 basal cortex(GO:0045180)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 5.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.0 GO:0070069 respiratory chain complex IV(GO:0045277) cytochrome complex(GO:0070069)
0.1 3.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 3.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 10.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 6.3 GO:0001726 ruffle(GO:0001726)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 3.4 GO:0016592 mediator complex(GO:0016592)
0.1 0.4 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 4.4 GO:0005795 Golgi stack(GO:0005795)
0.0 1.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 15.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 2.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 4.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 2.8 GO:0000323 lytic vacuole(GO:0000323)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.3 GO:0009374 biotin binding(GO:0009374)
1.6 4.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.4 4.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
1.2 4.6 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.9 2.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.9 2.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.7 3.6 GO:0060182 apelin receptor activity(GO:0060182)
0.7 3.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.7 11.1 GO:0032190 acrosin binding(GO:0032190)
0.4 2.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 1.4 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.4 1.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 7.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.4 2.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.3 8.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 4.4 GO:0038191 neuropilin binding(GO:0038191)
0.3 3.4 GO:0031720 haptoglobin binding(GO:0031720)
0.3 6.4 GO:0043236 laminin binding(GO:0043236)
0.3 4.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 3.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 3.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 8.5 GO:0019843 rRNA binding(GO:0019843)
0.2 2.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 11.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 1.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 1.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.4 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 5.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 3.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 5.0 GO:0009055 electron carrier activity(GO:0009055)
0.1 2.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 5.9 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 21.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 4.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 3.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 4.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.9 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.2 GO:0005109 frizzled binding(GO:0005109)
0.1 1.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 8.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 2.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 3.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 1.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.7 GO:0042562 hormone binding(GO:0042562)
0.0 2.3 GO:0019955 cytokine binding(GO:0019955)
0.0 6.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 7.1 GO:0051015 actin filament binding(GO:0051015)
0.0 5.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 3.5 GO:0003779 actin binding(GO:0003779)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.6 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.2 PID CONE PATHWAY Visual signal transduction: Cones
0.2 4.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 6.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 8.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.4 PID EPO PATHWAY EPO signaling pathway
0.1 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 18.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 2.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 3.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 4.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 6.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 8.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 4.6 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)