ISMARA results: TCF4_id4_mespaa+mespab+mespba+mespbb

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 0.95

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Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Gene Symbol	Gene ID	Gene Info
TCF4 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000107408	transcription factor 4
id4 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000045131	inhibitor of DNA binding 4
mespaa NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000017078	mesoderm posterior aa
mespba NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000030347	mesoderm posterior ba
mespab NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000068761	mesoderm posterior ab
mespbb NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000097947	mesoderm posterior bb
mespba NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000110553	mesoderm posterior ba
mespaa NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000114890	mesoderm posterior aa

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
id4	dr11_v1_chr16_-_9980402_9980402	-0.42	3.1e-05	Click!
TCF4	dr11_v1_chr21_+_1382078_1382078	-0.30	3.3e-03	Click!
mespaa	dr11_v1_chr7_+_15308042_15308042	-0.22	3.7e-02	Click!
mespab	dr11_v1_chr25_-_11016675_11016675	-0.19	6.4e-02	Click!
mespba	dr11_v1_chr7_+_15313443_15313443	0.08	4.5e-01	Click!
mespbb	dr11_v1_chr25_-_11026907_11026907	-0.05	6.0e-01	Click!

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_-_36834505 Show fit	11.39	ENSDART00000141275 ENSDART00000139588 ENSDART00000041993	pnp4b NCBI UniProt ZFIN ENSEMBL Google Show fit	purine nucleoside phosphorylase 4b
chr19_-_48312109 Show fit	11.29	ENSDART00000161103	si:ch73-359m17.9 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-359m17.9
chr20_-_42702832 Show fit	10.08	ENSDART00000134689 ENSDART00000045816	plg NCBI UniProt ZFIN ENSEMBL Google Show fit	plasminogen
chr2_-_47620806 Show fit	7.95	ENSDART00000038228	ap1s3b NCBI UniProt ZFIN ENSEMBL Google Show fit	adaptor-related protein complex 1, sigma 3 subunit, b
chr3_+_42923275 Show fit	7.47	ENSDART00000168228	tmem184a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 184a
chr2_-_22688651 Show fit	7.20	ENSDART00000013863	agxtb NCBI UniProt ZFIN ENSEMBL Google Show fit	alanine-glyoxylate aminotransferase b
chr16_+_52512025 Show fit	6.83	ENSDART00000056095	fabp10a NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid binding protein 10a, liver basic
chr6_+_29305190 Show fit	5.46	ENSDART00000078647	si:ch211-201h21.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-201h21.5
chr13_-_21672131 Show fit	5.19	ENSDART00000067537	elovl6l NCBI UniProt ZFIN ENSEMBL Google Show fit	ELOVL family member 6, elongation of long chain fatty acids like
chr6_-_40058686 Show fit	5.08	ENSDART00000103240	uroc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	urocanate hydratase 1
chr22_+_661711 Show fit	5.04	ENSDART00000113795	elf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_+_58751504 Show fit	4.95	ENSDART00000024185	zgc:56231 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:56231
chr12_-_23365737 Show fit	4.92	ENSDART00000170376	mpp7a NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr9_-_34269066 Show fit	4.81	ENSDART00000059955	ildr1b NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin-like domain containing receptor 1b
chr15_-_43164591 Show fit	4.70	ENSDART00000171305	ap1s3a NCBI UniProt ZFIN ENSEMBL Google Show fit	adaptor-related protein complex 1, sigma 3 subunit, a
chr4_+_72797711 Show fit	4.63	ENSDART00000190934 ENSDART00000163236	MYRFL NCBI UniProt ZFIN ENSEMBL Google Show fit	myelin regulatory factor-like
chr14_+_11458044 Show fit	4.62	ENSDART00000186425	si:ch211-153b23.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-153b23.5
chr22_+_7439476 Show fit	4.45	ENSDART00000021594 ENSDART00000063389	zgc:92041 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:92041
chr25_-_4146947 Show fit	4.44	ENSDART00000129268	fads2 NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid desaturase 2
chr8_+_15254564 Show fit	4.37	ENSDART00000024433	slc5a9 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 5 (sodium/sugar cotransporter), member 9
chr22_+_661505 Show fit	4.31	ENSDART00000149460	elf3 NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr25_-_32311048 Show fit	4.28	ENSDART00000181806 ENSDART00000086334	CU372926.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr22_-_17677947 Show fit	4.21	ENSDART00000139911	tjp3 NCBI UniProt ZFIN ENSEMBL Google Show fit	tight junction protein 3
chr2_-_41942666 Show fit	4.14	ENSDART00000075673	ebi3 NCBI UniProt ZFIN ENSEMBL Google Show fit	Epstein-Barr virus induced 3
chr21_-_34261677 Show fit	4.01	ENSDART00000124649 ENSDART00000172381 ENSDART00000064320	alg13 NCBI UniProt ZFIN ENSEMBL Google Show fit	ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr5_-_6567464 Show fit	3.99	ENSDART00000184985	tnks1bp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	tankyrase 1 binding protein 1
chr21_-_30293224 Show fit	3.94	ENSDART00000101051	slbp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	stem-loop binding protein 2
chr14_+_11457500 Show fit	3.90	ENSDART00000169202	si:ch211-153b23.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-153b23.5
chr4_-_9549693 Show fit	3.89	ENSDART00000160242	FQ377934.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr15_+_20239141 Show fit	3.83	ENSDART00000101152 ENSDART00000152473	spint2 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine peptidase inhibitor, Kunitz type, 2
chr21_-_25756119 Show fit	3.80	ENSDART00000002341	cldnc NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin c
chr6_+_45918981 Show fit	3.77	ENSDART00000149642	h6pd NCBI UniProt ZFIN ENSEMBL Google Show fit	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_+_7358749 Show fit	3.76	ENSDART00000081660	ihha NCBI UniProt ZFIN ENSEMBL Google Show fit	Indian hedgehog homolog a
chr6_+_10333920 Show fit	3.73	ENSDART00000151667 ENSDART00000151477	cobll1a NCBI UniProt ZFIN ENSEMBL Google Show fit	cordon-bleu WH2 repeat protein-like 1a
chr6_+_42338309 Show fit	3.72	ENSDART00000015277	gpx1b NCBI UniProt ZFIN ENSEMBL Google Show fit	glutathione peroxidase 1b
chr7_+_7048245 Show fit	3.71	ENSDART00000001649	actn3b NCBI UniProt ZFIN ENSEMBL Google Show fit	actinin alpha 3b
chr5_-_38451082 Show fit	3.64	ENSDART00000136428	chrne NCBI UniProt ZFIN ENSEMBL Google Show fit	cholinergic receptor, nicotinic, epsilon
chr21_-_26114886 Show fit	3.64	ENSDART00000139320	nipal4 NCBI UniProt ZFIN ENSEMBL Google Show fit	NIPA-like domain containing 4
chr7_+_61184551 Show fit	3.57	ENSDART00000190788	zgc:194930 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194930
chr3_+_62161184 Show fit	3.57	ENSDART00000090370 ENSDART00000192665	noxo1a NCBI UniProt ZFIN ENSEMBL Google Show fit	NADPH oxidase organizer 1a
chr25_-_3867990 Show fit	3.54	ENSDART00000075663	cracr2b NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium release activated channel regulator 2B
chr12_+_46543572 Show fit	3.51	ENSDART00000167510	hid1b NCBI UniProt ZFIN ENSEMBL Google Show fit	HID1 domain containing b
chr1_-_18811517 Show fit	3.48	ENSDART00000142026	si:dkey-167i21.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-167i21.2
chr6_-_609880 Show fit	3.46	ENSDART00000149248 ENSDART00000148867 ENSDART00000149414 ENSDART00000148552 ENSDART00000148391	lgals2b NCBI UniProt ZFIN ENSEMBL Google Show fit	lectin, galactoside-binding, soluble, 2b
chr21_-_43666420 Show fit	3.44	ENSDART00000139008 ENSDART00000183996 ENSDART00000183395	si:dkey-229d11.3 NCBI UniProt ZFIN ENSEMBL Google Show fit si:dkey-229d11.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-229d11.3 si:dkey-229d11.5
chr14_-_33277743 Show fit	3.44	ENSDART00000048130	stard14 NCBI UniProt ZFIN ENSEMBL Google Show fit	START domain containing 14
chr23_-_31266586 Show fit	3.43	ENSDART00000139746	si:dkey-261l7.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-261l7.2
chr22_-_25612680 Show fit	3.41	ENSDART00000114167	si:ch211-12h2.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-12h2.8
chr21_-_40630650 Show fit	3.39	ENSDART00000172706	pcyt1bb NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphate cytidylyltransferase 1, choline, beta b
chr10_+_3520256 Show fit	3.35	ENSDART00000003242	zgc:123275 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:123275
chr17_+_53294228 Show fit	3.34	ENSDART00000158172	si:ch1073-416d2.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-416d2.3
chr16_-_17713859 Show fit	3.34	ENSDART00000149275	zgc:174935 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:174935
chr13_-_34683370 Show fit	3.33	ENSDART00000113661	kif16bb NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 16Bb
chr11_+_329687 Show fit	3.30	ENSDART00000172882	cyp27b1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_+_9191981 Show fit	3.27	ENSDART00000150916	zgc:112392 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:112392
chr9_+_310331 Show fit	3.23	ENSDART00000172446 ENSDART00000187731 ENSDART00000193970	stac3 NCBI UniProt ZFIN ENSEMBL Google Show fit	SH3 and cysteine rich domain 3
chr21_-_39024754 Show fit	3.22	ENSDART00000056878	traf4b NCBI UniProt ZFIN ENSEMBL Google Show fit	tnf receptor-associated factor 4b
chr5_-_69948099 Show fit	3.17	ENSDART00000034639 ENSDART00000191111	ugt2a4 NCBI UniProt ZFIN ENSEMBL Google Show fit	UDP glucuronosyltransferase 2 family, polypeptide A4
chr10_-_25217347 Show fit	3.16	ENSDART00000036906	kpna7 NCBI UniProt ZFIN ENSEMBL Google Show fit	karyopherin alpha 7 (importin alpha 8)
chr7_-_38644560 Show fit	3.15	ENSDART00000114934	c6ast3 NCBI UniProt ZFIN ENSEMBL Google Show fit	six-cysteine containing astacin protease 3
chr24_-_25244637 Show fit	3.12	ENSDART00000153798	hhla2b.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	HERV-H LTR-associating 2b, tandem duplicate 2
chr1_-_12027 Show fit	3.12	ENSDART00000164359	rpl24 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein L24
chr7_+_39446247 Show fit	3.07	ENSDART00000033610 ENSDART00000099015	tnnt3b NCBI UniProt ZFIN ENSEMBL Google Show fit	troponin T type 3b (skeletal, fast)
chr17_-_30473374 Show fit	2.97	ENSDART00000155021	si:ch211-175f11.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-175f11.5
chr12_+_6041575 Show fit	2.97	ENSDART00000091868	g6pca.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr7_-_53117131 Show fit	2.96	ENSDART00000169211 ENSDART00000168890 ENSDART00000172179 ENSDART00000167882	cdh1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cadherin 1, type 1, E-cadherin (epithelial)
chr7_+_57088920 Show fit	2.94	ENSDART00000024076	scamp2l NCBI UniProt ZFIN ENSEMBL Google Show fit	secretory carrier membrane protein 2, like
chr13_-_12581388 Show fit	2.93	ENSDART00000079655	enpep NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamyl aminopeptidase
chr11_-_37995501 Show fit	2.87	ENSDART00000192096	slc41a1 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 41 (magnesium transporter), member 1
chr19_+_2590182 Show fit	2.86	ENSDART00000162293	si:ch73-345f18.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-345f18.3
chr16_+_46695777 Show fit	2.84	ENSDART00000169767	rab25b NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB25, member RAS oncogene family b
chr3_-_26204867 Show fit	2.82	ENSDART00000103748	gdpd3a NCBI UniProt ZFIN ENSEMBL Google Show fit	glycerophosphodiester phosphodiesterase domain containing 3a
chr2_-_24402341 Show fit	2.81	ENSDART00000155442 ENSDART00000088572	zgc:154006 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:154006
chr1_+_30422143 Show fit	2.81	ENSDART00000033024	tmem41ab NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 41ab
chr22_+_11756040 Show fit	2.80	ENSDART00000105808	krt97 NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 97
chr16_-_42066523 Show fit	2.80	ENSDART00000180538 ENSDART00000058620	zp3d.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3d tandem duplicate 1
chr20_+_10538025 Show fit	2.79	ENSDART00000129762	serpina1l NCBI UniProt ZFIN ENSEMBL Google Show fit	serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr7_-_38644287 Show fit	2.77	ENSDART00000182307	c6ast3 NCBI UniProt ZFIN ENSEMBL Google Show fit	six-cysteine containing astacin protease 3
chr21_-_25741411 Show fit	2.73	ENSDART00000101211	cldnh NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin h
chr25_-_13614863 Show fit	2.73	ENSDART00000121859	fa2h NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid 2-hydroxylase
chr24_-_25691020 Show fit	2.72	ENSDART00000015391	chrnd NCBI UniProt ZFIN ENSEMBL Google Show fit	cholinergic receptor, nicotinic, delta (muscle)
chr18_+_45666489 Show fit	2.69	ENSDART00000180147 ENSDART00000151351	prrg4 NCBI UniProt ZFIN ENSEMBL Google Show fit	proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr7_+_30392613 Show fit	2.63	ENSDART00000075508	lipca NCBI UniProt ZFIN ENSEMBL Google Show fit	lipase, hepatic a
chr5_-_23696926 Show fit	2.63	ENSDART00000021462	rnf128a NCBI UniProt ZFIN ENSEMBL Google Show fit	ring finger protein 128a
chr23_-_29556844 Show fit	2.59	ENSDART00000138021	rbp7a NCBI UniProt ZFIN ENSEMBL Google Show fit	retinol binding protein 7a, cellular
chr19_+_48117995 Show fit	2.59	ENSDART00000170865	nme2b.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr10_-_2942900 Show fit	2.59	ENSDART00000002622	oclna NCBI UniProt ZFIN ENSEMBL Google Show fit	occludin a
chr6_+_6780873 Show fit	2.58	ENSDART00000011865	sec23b NCBI UniProt ZFIN ENSEMBL Google Show fit	Sec23 homolog B, COPII coat complex component
chr14_-_46198373 Show fit	2.57	ENSDART00000031640 ENSDART00000132966	zgc:113425 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:113425
chr14_+_15155684 Show fit	2.55	ENSDART00000167966	zgc:158852 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:158852
chr14_-_33278084 Show fit	2.53	ENSDART00000132850	stard14 NCBI UniProt ZFIN ENSEMBL Google Show fit	START domain containing 14
chr9_+_307863 Show fit	2.52	ENSDART00000163474	stac3 NCBI UniProt ZFIN ENSEMBL Google Show fit	SH3 and cysteine rich domain 3
chr17_+_30894431 Show fit	2.50	ENSDART00000127996	degs2 NCBI UniProt ZFIN ENSEMBL Google Show fit	delta(4)-desaturase, sphingolipid 2
chr3_+_36424055 Show fit	2.49	ENSDART00000170318	si:ch1073-443f11.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-443f11.2
chr23_+_39854566 Show fit	2.48	ENSDART00000190423 ENSDART00000164473 ENSDART00000161881	si:ch73-217b7.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-217b7.1
chr23_+_553396 Show fit	2.44	ENSDART00000034707	lsm14b NCBI UniProt ZFIN ENSEMBL Google Show fit	LSM family member 14B
chr6_-_13498745 Show fit	2.43	ENSDART00000027684 ENSDART00000189438	mylkb NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin light chain kinase b
chr12_-_28818720 Show fit	2.43	ENSDART00000134453 ENSDART00000141727	prr15lb NCBI UniProt ZFIN ENSEMBL Google Show fit	proline rich 15-like b
chr3_+_14388010 Show fit	2.42	ENSDART00000171726 ENSDART00000165452	tmem56b NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 56b
chr5_-_32338866 Show fit	2.41	ENSDART00000017956 ENSDART00000047670	dab2 NCBI UniProt ZFIN ENSEMBL Google Show fit	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr25_-_17587785 Show fit	2.40	ENSDART00000073679 ENSDART00000146851	zgc:66449 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:66449
chr11_-_34097418 Show fit	2.38	ENSDART00000028301 ENSDART00000138579	tdo2b NCBI UniProt ZFIN ENSEMBL Google Show fit	tryptophan 2,3-dioxygenase b
chr1_-_20593778 Show fit	2.38	ENSDART00000124770	ugt8 NCBI UniProt ZFIN ENSEMBL Google Show fit	UDP glycosyltransferase 8
chr20_+_46924390 Show fit	2.34	ENSDART00000132161	si:ch73-21k16.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-21k16.5
chr22_+_7480465 Show fit	2.33	ENSDART00000034545	CELA1 (1 of many) NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:92745
chr6_-_130849 Show fit	2.33	ENSDART00000108710	LRRC8E NCBI UniProt ZFIN ENSEMBL Google Show fit	si:zfos-323e3.4
chr7_+_32901658 Show fit	2.29	ENSDART00000115420	ano9b NCBI UniProt ZFIN ENSEMBL Google Show fit	anoctamin 9b
chr15_-_3282220 Show fit	2.29	ENSDART00000092942	slc25a15a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr4_-_948776 Show fit	2.29	ENSDART00000023483	sim1b NCBI UniProt ZFIN ENSEMBL Google Show fit	single-minded family bHLH transcription factor 1b
chr3_+_25849560 Show fit	2.28	ENSDART00000007119	mfsd6l NCBI UniProt ZFIN ENSEMBL Google Show fit	major facilitator superfamily domain containing 6-like
chr25_+_5249513 Show fit	2.26	ENSDART00000126814	CABZ01039863.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr14_-_83154 Show fit	2.25	ENSDART00000187097	CABZ01086812.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr25_-_17395315 Show fit	2.25	ENSDART00000064596	cyp2x8 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 2, subfamily X, polypeptide 8
chr13_+_50375800 Show fit	2.25	ENSDART00000099537	cox5b2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome c oxidase subunit Vb 2
chr14_-_36862745 Show fit	2.24	ENSDART00000109293	rnf130 NCBI UniProt ZFIN ENSEMBL Google Show fit	ring finger protein 130
chr9_-_39005317 Show fit	2.21	ENSDART00000014207	myl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin, light chain 1, alkali; skeletal, fast
chr15_+_29025090 Show fit	2.20	ENSDART00000131755	si:ch211-137a8.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-137a8.2
chr1_-_50247 Show fit	2.19	ENSDART00000168428	ildr1a NCBI UniProt ZFIN ENSEMBL Google Show fit	immunoglobulin-like domain containing receptor 1a
chr1_-_29747702 Show fit	2.19	ENSDART00000133225 ENSDART00000189670	spp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	secreted phosphoprotein 2
chr11_-_25853212 Show fit	2.18	ENSDART00000145655	tmem51b NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 51b
chr13_-_41908583 Show fit	2.16	ENSDART00000136515	ipmka NCBI UniProt ZFIN ENSEMBL Google Show fit	inositol polyphosphate multikinase a
chr13_-_50108337 Show fit	2.16	ENSDART00000133308	nid1a NCBI UniProt ZFIN ENSEMBL Google Show fit	nidogen 1a
chr19_-_42551338 Show fit	2.15	ENSDART00000162837	zgc:123103 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:123103
chr18_-_502722 Show fit	2.15	ENSDART00000185757	sdr42e1 NCBI UniProt ZFIN ENSEMBL Google Show fit	short chain dehydrogenase/reductase family 42E, member 1
chr10_+_34001444 Show fit	2.15	ENSDART00000149934	kl NCBI UniProt ZFIN ENSEMBL Google Show fit	klotho
chr19_+_7636941 Show fit	2.14	ENSDART00000081611 ENSDART00000163805 ENSDART00000112404	cgnb NCBI UniProt ZFIN ENSEMBL Google Show fit	cingulin b
chr2_+_6253246 Show fit	2.14	ENSDART00000058256 ENSDART00000076700	zp3b NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida glycoprotein 3b
chr22_+_7439186 Show fit	2.10	ENSDART00000190667	zgc:92041 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:92041
chr16_+_34111919 Show fit	2.10	ENSDART00000134037 ENSDART00000006061 ENSDART00000140552	tcea3 NCBI UniProt ZFIN ENSEMBL Google Show fit	transcription elongation factor A (SII), 3
chr1_+_24387659 Show fit	2.06	ENSDART00000130356	qdprb2 NCBI UniProt ZFIN ENSEMBL Google Show fit	quinoid dihydropteridine reductase b2
chr14_+_32964 Show fit	2.04	ENSDART00000166173	lyar NCBI UniProt ZFIN ENSEMBL Google Show fit	Ly1 antibody reactive homolog (mouse)
chr11_-_165288 Show fit	2.04	ENSDART00000108703 ENSDART00000173151	tegt NCBI UniProt ZFIN ENSEMBL Google Show fit	testis enhanced gene transcript (BAX inhibitor 1)
chr17_-_25331439 Show fit	2.03	ENSDART00000155422 ENSDART00000082324	zpcx NCBI UniProt ZFIN ENSEMBL Google Show fit	zona pellucida protein C
chr3_+_14641962 Show fit	2.03	ENSDART00000091070	zgc:158403 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:158403
chr7_+_6969909 Show fit	2.02	ENSDART00000189886	actn3b NCBI UniProt ZFIN ENSEMBL Google Show fit	actinin alpha 3b
chr23_+_44881020 Show fit	2.00	ENSDART00000149355	si:ch73-361h17.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-361h17.1
chr8_-_47844456 Show fit	1.99	ENSDART00000145429	si:dkeyp-104h9.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkeyp-104h9.5
chr24_+_35564668 Show fit	1.99	ENSDART00000122734	cebpd NCBI UniProt ZFIN ENSEMBL Google Show fit	CCAAT/enhancer binding protein (C/EBP), delta
chr3_+_32526799 Show fit	1.99	ENSDART00000185755	si:ch73-367p23.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-367p23.2
chr17_-_52595932 Show fit	1.95	ENSDART00000127225	si:ch211-173a9.7 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-173a9.7
chr9_-_16109001 Show fit	1.95	ENSDART00000053473	upp2 NCBI UniProt ZFIN ENSEMBL Google Show fit	uridine phosphorylase 2
chr2_+_17181777 Show fit	1.95	ENSDART00000112063	ptger4c NCBI UniProt ZFIN ENSEMBL Google Show fit	prostaglandin E receptor 4 (subtype EP4) c
chr17_-_5878032 Show fit	1.94	ENSDART00000148916	gckr NCBI UniProt ZFIN ENSEMBL Google Show fit	glucokinase (hexokinase 4) regulator
chr16_+_46725087 Show fit	1.94	ENSDART00000008920	rab11al NCBI UniProt ZFIN ENSEMBL Google Show fit	RAB11a, member RAS oncogene family, like
chr2_+_11031360 Show fit	1.93	ENSDART00000180020 ENSDART00000145093	acot11a NCBI UniProt ZFIN ENSEMBL Google Show fit	acyl-CoA thioesterase 11a
chr22_-_10541372 Show fit	1.93	ENSDART00000179708	si:dkey-42i9.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-42i9.4
chr16_+_23975930 Show fit	1.92	ENSDART00000147858 ENSDART00000144347 ENSDART00000115270	apoc4 NCBI UniProt ZFIN ENSEMBL Google Show fit	apolipoprotein C-IV
chr17_-_36860988 Show fit	1.92	ENSDART00000154981	senp6b NCBI UniProt ZFIN ENSEMBL Google Show fit	SUMO1/sentrin specific peptidase 6b
chr6_+_153146 Show fit	1.91	ENSDART00000097468	zglp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger, GATA-like protein 1
chr25_+_7492663 Show fit	1.89	ENSDART00000166496	cat NCBI UniProt ZFIN ENSEMBL Google Show fit	catalase
chr8_+_29593986 Show fit	1.88	ENSDART00000077642	atoh1a NCBI UniProt ZFIN ENSEMBL Google Show fit	atonal bHLH transcription factor 1a
chr21_-_25741096 Show fit	1.88	ENSDART00000181756	cldnh NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin h
chr21_-_19919020 Show fit	1.88	ENSDART00000147396	ppp1r3b NCBI UniProt ZFIN ENSEMBL Google Show fit	protein phosphatase 1, regulatory subunit 3B
chr17_+_39242437 Show fit	1.86	ENSDART00000156138 ENSDART00000128863	zgc:174356 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:174356
chr16_-_25608453 Show fit	1.85	ENSDART00000140140	zgc:110410 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:110410
chr12_+_13091842 Show fit	1.85	ENSDART00000185477 ENSDART00000181435 ENSDART00000124799	si:ch211-103b1.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-103b1.2
chr5_-_25723079 Show fit	1.84	ENSDART00000014013	gda NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine deaminase
chr2_+_27855346 Show fit	1.84	ENSDART00000175159 ENSDART00000192645	buc NCBI UniProt ZFIN ENSEMBL Google Show fit	bucky ball
chr5_-_69212184 Show fit	1.83	ENSDART00000053963	mat2ab NCBI UniProt ZFIN ENSEMBL Google Show fit	methionine adenosyltransferase II, alpha b
chr12_+_19401854 Show fit	1.83	ENSDART00000153415	si:dkey-16i5.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-16i5.8
chr10_+_29771256 Show fit	1.82	ENSDART00000193195	hyou1 NCBI UniProt ZFIN ENSEMBL Google Show fit	hypoxia up-regulated 1
chr15_-_3277635 Show fit	1.82	ENSDART00000189094	slc25a15a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr10_+_38775408 Show fit	1.82	ENSDART00000125045	dscama NCBI UniProt ZFIN ENSEMBL Google Show fit	Down syndrome cell adhesion molecule a
chr21_-_7928101 Show fit	1.82	ENSDART00000151543 ENSDART00000114982	f2rl1.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr19_-_27339670 Show fit	1.82	ENSDART00000139323	znrd1 NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc ribbon domain containing 1
chr17_-_5610514 Show fit	1.81	ENSDART00000004043	enpp4 NCBI UniProt ZFIN ENSEMBL Google Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 4
chr15_+_43906043 Show fit	1.81	ENSDART00000010881	naalad2 NCBI UniProt ZFIN ENSEMBL Google Show fit	N-acetylated alpha-linked acidic dipeptidase 2
chr10_-_2943474 Show fit	1.81	ENSDART00000188698	oclna NCBI UniProt ZFIN ENSEMBL Google Show fit	occludin a
chr17_+_51906053 Show fit	1.80	ENSDART00000159072 ENSDART00000056869	flvcr2a NCBI UniProt ZFIN ENSEMBL Google Show fit	feline leukemia virus subgroup C cellular receptor family, member 2a
chr12_-_48312647 Show fit	1.79	ENSDART00000114415	ascc1 NCBI UniProt ZFIN ENSEMBL Google Show fit	activating signal cointegrator 1 complex subunit 1
chr13_+_33606739 Show fit	1.79	ENSDART00000026464	cfl1l NCBI UniProt ZFIN ENSEMBL Google Show fit	cofilin 1 (non-muscle), like
chr21_-_20725853 Show fit	1.79	ENSDART00000114502	si:ch211-22d5.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-22d5.2
chr22_+_11775269 Show fit	1.79	ENSDART00000140272	krt96 NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 96
chr23_+_26733232 Show fit	1.78	ENSDART00000035080	zgc:158263 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:158263
chr22_-_10110959 Show fit	1.76	ENSDART00000031005 ENSDART00000147580	gls2b NCBI UniProt ZFIN ENSEMBL Google Show fit	glutaminase 2b (liver, mitochondrial)
chr3_-_40275096 Show fit	1.75	ENSDART00000141578	shmt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine hydroxymethyltransferase 1 (soluble)
chr24_-_24983047 Show fit	1.74	ENSDART00000066631	slc51a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 51, alpha subunit
chr7_-_55648336 Show fit	1.73	ENSDART00000147792 ENSDART00000135304 ENSDART00000131923	pabpn1l NCBI UniProt ZFIN ENSEMBL Google Show fit	poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr10_-_1961930 Show fit	1.73	ENSDART00000122446	tdgf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	teratocarcinoma-derived growth factor 1
chr8_+_6576940 Show fit	1.73	ENSDART00000138135	vsig8b NCBI UniProt ZFIN ENSEMBL Google Show fit	V-set and immunoglobulin domain containing 8b
chr2_-_50225411 Show fit	1.71	ENSDART00000147117 ENSDART00000000042	mcm6l NCBI UniProt ZFIN ENSEMBL Google Show fit	MCM6 minichromosome maintenance deficient 6, like
chr22_+_34710036 Show fit	1.71	ENSDART00000025820	hoga1 NCBI UniProt ZFIN ENSEMBL Google Show fit	4-hydroxy-2-oxoglutarate aldolase 1
chr2_-_43698531 Show fit	1.71	ENSDART00000170968	FO704635.1 NCBI UniProt ZFIN ENSEMBL Google Show fit
chr17_+_53292215 Show fit	1.70	ENSDART00000170686	si:ch1073-416d2.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-416d2.3
chr20_-_21672970 Show fit	1.70	ENSDART00000133286	si:ch211-207i1.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-207i1.2
chr2_-_58075414 Show fit	1.69	ENSDART00000161920	nectin4 NCBI UniProt ZFIN ENSEMBL Google Show fit	nectin cell adhesion molecule 4
chr21_+_38817785 Show fit	1.69	ENSDART00000177616 ENSDART00000149085	hnf1bb NCBI UniProt ZFIN ENSEMBL Google Show fit	HNF1 homeobox Bb
chr16_+_23976227 Show fit	1.69	ENSDART00000193013	apoc4 NCBI UniProt ZFIN ENSEMBL Google Show fit	apolipoprotein C-IV
chr21_-_22543611 Show fit	1.69	ENSDART00000177084	myo5b NCBI UniProt ZFIN ENSEMBL Google Show fit	myosin VB
chr23_+_9867483 Show fit	1.67	ENSDART00000023099	slc16a7 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr19_+_791538 Show fit	1.67	ENSDART00000146554 ENSDART00000138406	tmem79a NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 79a
chr15_-_33964897 Show fit	1.66	ENSDART00000172075 ENSDART00000158126 ENSDART00000160456	lsr NCBI UniProt ZFIN ENSEMBL Google Show fit	lipolysis stimulated lipoprotein receptor
chr24_+_10898671 Show fit	1.65	ENSDART00000106272	si:dkey-37o8.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-37o8.1
chr5_-_23715861 Show fit	1.65	ENSDART00000019992	gbgt1l1 NCBI UniProt ZFIN ENSEMBL Google Show fit	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr7_+_61184104 Show fit	1.65	ENSDART00000110671	zgc:194930 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:194930
chr10_+_38775959 Show fit	1.64	ENSDART00000192990	dscama NCBI UniProt ZFIN ENSEMBL Google Show fit	Down syndrome cell adhesion molecule a
chr2_-_37280617 Show fit	1.64	ENSDART00000190458	nadkb NCBI UniProt ZFIN ENSEMBL Google Show fit	NAD kinase b
chr11_-_28050559 Show fit	1.64	ENSDART00000136859	ece1 NCBI UniProt ZFIN ENSEMBL Google Show fit	endothelin converting enzyme 1
chr7_+_14005111 Show fit	1.63	ENSDART00000187365	furina NCBI UniProt ZFIN ENSEMBL Google Show fit	furin (paired basic amino acid cleaving enzyme) a
chr3_-_61494840 Show fit	1.63	ENSDART00000101957	baiap2l1b NCBI UniProt ZFIN ENSEMBL Google Show fit	BAI1-associated protein 2-like 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	10.1	GO:0042730	fibrinolysis(GO:0042730)
1.7	5.1	GO:0019556	formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.5	9.0	GO:0006545	glycine biosynthetic process(GO:0006545)
1.4	4.1	GO:0044321	leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
1.4	4.1	GO:1990575	mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
1.2	5.8	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
1.0	3.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
1.0	3.1	GO:0090008	hypoblast development(GO:0090008)
0.8	3.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.7	12.5	GO:2000344	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7	4.6	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.6	1.9	GO:0009750	response to fructose(GO:0009750)
0.6	4.5	GO:0040016	embryonic cleavage(GO:0040016)
0.6	1.9	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.6	1.9	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.6	3.7	GO:0010269	response to selenium ion(GO:0010269)
0.6	1.8	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.6	1.8	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.6	1.8	GO:0030043	actin filament fragmentation(GO:0030043)
0.6	3.9	GO:0006741	NADP biosynthetic process(GO:0006741)
0.5	3.1	GO:0060832	oocyte animal/vegetal axis specification(GO:0060832)
0.5	1.5	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.5	1.5	GO:0030237	female sex determination(GO:0030237)
0.5	2.5	GO:0043420	anthranilate metabolic process(GO:0043420)
0.5	2.4	GO:0006535	cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.5	0.5	GO:0018057	peptidyl-lysine oxidation(GO:0018057)
0.5	1.9	GO:0090230	regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.5	1.4	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.5	2.7	GO:0090134	mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.5	1.8	GO:0097037	heme export(GO:0097037)
0.4	4.4	GO:0030104	water homeostasis(GO:0030104)
0.4	1.7	GO:0003241	growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.4	4.0	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.4	2.4	GO:0046218	tryptophan metabolic process(GO:0006568) tryptophan catabolic process(GO:0006569) indolalkylamine metabolic process(GO:0006586) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.4	1.9	GO:0071380	response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.4	1.5	GO:0032206	positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.4	2.9	GO:0006543	glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.4	0.7	GO:0090435	protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.3	1.4	GO:0042755	eating behavior(GO:0042755)
0.3	3.5	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.3	3.8	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.3	3.0	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3	2.4	GO:2000725	regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.3	1.2	GO:0042985	negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.3	0.9	GO:0048496	maintenance of organ identity(GO:0048496)
0.3	1.5	GO:0070986	left/right axis specification(GO:0070986)
0.3	1.5	GO:0032289	central nervous system myelin formation(GO:0032289)
0.3	2.9	GO:0034672	anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.3	1.7	GO:0060967	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3	1.7	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.3	4.2	GO:0015693	magnesium ion transport(GO:0015693)
0.3	4.8	GO:0048922	posterior lateral line neuromast deposition(GO:0048922)
0.3	0.8	GO:0065001	specification of axis polarity(GO:0065001)
0.3	3.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.3	1.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.3	4.7	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.3	1.3	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.3	2.3	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3	3.8	GO:0016486	peptide hormone processing(GO:0016486)
0.2	2.7	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.2	0.7	GO:1901232	regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.2	0.7	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.2	1.0	GO:0070166	enamel mineralization(GO:0070166)
0.2	1.2	GO:0033499	galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.2	3.9	GO:0019433	triglyceride catabolic process(GO:0019433)
0.2	2.3	GO:0061588	calcium activated phospholipid scrambling(GO:0061588)
0.2	0.7	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.2	2.5	GO:1902299	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2	1.5	GO:1900048	positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2	0.6	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.2	1.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.2	0.6	GO:0060292	long term synaptic depression(GO:0060292)
0.2	0.4	GO:0048521	negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.2	1.9	GO:0010138	pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.2	0.8	GO:0070291	N-acylethanolamine metabolic process(GO:0070291)
0.2	1.5	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.2	2.5	GO:0034311	diol metabolic process(GO:0034311)
0.2	0.7	GO:0048913	anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.2	1.2	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.2	0.7	GO:0016139	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.2	0.7	GO:0003400	regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2	2.6	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.2	1.0	GO:0008207	C21-steroid hormone metabolic process(GO:0008207)
0.2	2.0	GO:0042542	response to hydrogen peroxide(GO:0042542)
0.2	0.3	GO:0035676	anterior lateral line neuromast hair cell development(GO:0035676)
0.2	0.7	GO:0006844	acyl carnitine transport(GO:0006844)
0.2	1.0	GO:0006004	fucose metabolic process(GO:0006004)
0.2	2.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.2	0.8	GO:1902514	calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2	0.5	GO:0002369	T cell cytokine production(GO:0002369)
0.2	3.4	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2	0.5	GO:2000648	neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.2	0.5	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.2	1.2	GO:0042554	superoxide anion generation(GO:0042554)
0.2	1.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2	1.4	GO:0098789	mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	1.1	GO:0060017	parathyroid gland development(GO:0060017)
0.1	3.0	GO:0006801	superoxide metabolic process(GO:0006801)
0.1	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.1	0.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.7	GO:0007060	male meiosis chromosome segregation(GO:0007060)
0.1	0.8	GO:0015864	uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1	3.1	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	2.4	GO:0008078	mesodermal cell migration(GO:0008078)
0.1	0.6	GO:0015887	biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1	0.6	GO:0009097	isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1	1.2	GO:0034435	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1	0.4	GO:0009957	epidermal cell fate specification(GO:0009957)
0.1	0.9	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.1	0.7	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	5.9	GO:0043297	apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1	0.9	GO:0032196	transposition(GO:0032196)
0.1	0.7	GO:0009450	gamma-aminobutyric acid catabolic process(GO:0009450)
0.1	0.4	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.1	3.7	GO:0070593	dendrite self-avoidance(GO:0070593)
0.1	0.5	GO:0032208	regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1	0.5	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	0.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.8	GO:0045337	farnesyl diphosphate biosynthetic process(GO:0045337)
0.1	0.6	GO:0019359	NAD biosynthetic process(GO:0009435) nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
0.1	2.6	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	1.4	GO:0044247	polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1	0.9	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.1	0.7	GO:0015822	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1	1.5	GO:0016556	mRNA modification(GO:0016556)
0.1	0.5	GO:0055107	Golgi to secretory granule transport(GO:0055107)
0.1	1.5	GO:0032933	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	4.5	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.1	1.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.3	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.9	GO:0040038	meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1	0.5	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.3	GO:0042543	protein N-linked glycosylation via arginine(GO:0042543)
0.1	1.7	GO:0061055	myotome development(GO:0061055)
0.1	0.3	GO:1904478	regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1	2.7	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.1	2.2	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.1	1.8	GO:0030259	lipid glycosylation(GO:0030259)
0.1	1.0	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.3	GO:0044038	cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1	0.4	GO:2000392	lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1	0.6	GO:0006567	threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1	1.1	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1	1.1	GO:0018120	peptidyl-arginine ADP-ribosylation(GO:0018120)
0.1	0.6	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1	0.4	GO:0019566	arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1	1.2	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.1	0.2	GO:0048239	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1	0.4	GO:0042304	regulation of fatty acid biosynthetic process(GO:0042304)
0.1	0.9	GO:0009395	phospholipid catabolic process(GO:0009395)
0.1	0.3	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.7	GO:1990511	piRNA biosynthetic process(GO:1990511)
0.1	0.4	GO:0003322	pancreatic A cell development(GO:0003322)
0.1	0.6	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1	2.5	GO:0043171	peptide catabolic process(GO:0043171)
0.1	0.4	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867) positive regulation of triglyceride metabolic process(GO:0090208)
0.1	4.4	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.1	1.8	GO:0071456	cellular response to hypoxia(GO:0071456)
0.1	0.4	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.8	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.1	0.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	0.3	GO:1990697	protein depalmitoleylation(GO:1990697)
0.1	0.2	GO:2000108	positive regulation of leukocyte apoptotic process(GO:2000108)
0.1	0.3	GO:0036344	platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1	0.2	GO:0048340	paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1	0.2	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.6	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	6.8	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.1	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	1.0	GO:0042694	muscle cell fate specification(GO:0042694)
0.1	0.5	GO:0090497	mesenchymal cell migration(GO:0090497)
0.1	0.5	GO:0044209	AMP salvage(GO:0044209)
0.1	0.5	GO:0035627	ceramide transport(GO:0035627)
0.1	1.0	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	0.7	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	1.0	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	4.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.4	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.1	5.2	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1	4.7	GO:0006694	steroid biosynthetic process(GO:0006694)
0.1	0.3	GO:0001955	blood vessel maturation(GO:0001955)
0.1	3.5	GO:0042738	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1	0.4	GO:0034389	lipid particle organization(GO:0034389)
0.1	0.6	GO:0070293	renal absorption(GO:0070293)
0.1	0.9	GO:0001840	neural plate development(GO:0001840)
0.1	0.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	1.7	GO:0007097	nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1	2.1	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.1	8.1	GO:0045765	regulation of angiogenesis(GO:0045765)
0.1	0.2	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1	0.7	GO:0009303	rRNA transcription(GO:0009303)
0.1	0.3	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	1.9	GO:0007568	aging(GO:0007568)
0.1	0.4	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	1.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.7	GO:0032048	cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1	1.1	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
0.1	4.0	GO:0006414	translational elongation(GO:0006414)
0.1	1.4	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
0.1	0.3	GO:0072003	kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1	0.4	GO:0090594	inflammatory response to wounding(GO:0090594)
0.1	0.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.3	GO:0060437	lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1	0.3	GO:0061056	sclerotome development(GO:0061056)
0.1	0.3	GO:0010719	photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1	0.1	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
0.1	0.8	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	0.4	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.1	2.0	GO:0051346	negative regulation of hydrolase activity(GO:0051346)
0.1	0.2	GO:2000623	negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	0.9	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.5	GO:0008585	female gonad development(GO:0008585)
0.1	2.6	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1	0.2	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1	1.0	GO:0031297	replication fork processing(GO:0031297)
0.1	0.3	GO:0071691	cardiac muscle thin filament assembly(GO:0071691)
0.1	0.3	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.1	0.9	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1	0.2	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.1	0.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.2	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.2	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.3	GO:0010634	positive regulation of epithelial cell migration(GO:0010634)
0.0	2.3	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.3	GO:0002360	T-helper cell lineage commitment(GO:0002295) T cell lineage commitment(GO:0002360) alpha-beta T cell lineage commitment(GO:0002363) positive T cell selection(GO:0043368) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T cell selection(GO:0045058) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.2	GO:0010754	negative regulation of cGMP-mediated signaling(GO:0010754)
0.0	0.2	GO:0043011	myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0	0.4	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	1.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.2	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.0	0.6	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.7	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.4	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.2	GO:0006529	asparagine biosynthetic process(GO:0006529)
0.0	2.2	GO:0071466	cellular response to xenobiotic stimulus(GO:0071466)
0.0	0.4	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	1.1	GO:0048599	oocyte development(GO:0048599)
0.0	0.4	GO:0014034	neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0	1.9	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	1.3	GO:0044243	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0	0.9	GO:0046849	bone remodeling(GO:0046849)
0.0	0.1	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.5	GO:0050870	positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0	0.2	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.2	GO:0031106	septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0	0.6	GO:0046549	retinal cone cell development(GO:0046549)
0.0	0.1	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
0.0	0.3	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.3	GO:0071684	hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0	1.1	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.3	GO:1990845	adaptive thermogenesis(GO:1990845)
0.0	0.3	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.2	GO:0016074	snoRNA metabolic process(GO:0016074)
0.0	0.3	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0	8.0	GO:0006954	inflammatory response(GO:0006954)
0.0	0.4	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.1	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.0	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.2	GO:0097101	blood vessel endothelial cell fate specification(GO:0097101)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.4	GO:0035588	adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.7	GO:0022011	myelination in peripheral nervous system(GO:0022011)
0.0	1.2	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.3	GO:0010889	regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0	0.9	GO:0003323	glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.0	2.1	GO:0006672	ceramide metabolic process(GO:0006672)
0.0	0.3	GO:0060036	notochord cell vacuolation(GO:0060036)
0.0	0.1	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0	0.3	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	1.3	GO:0030282	bone mineralization(GO:0030282)
0.0	1.6	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0	1.4	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.7	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0055109	invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.0	0.9	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.8	GO:0008203	cholesterol metabolic process(GO:0008203)
0.0	0.3	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.4	GO:0060416	growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	1.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.4	GO:1901888	regulation of cell junction assembly(GO:1901888)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	1.6	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.4	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	1.5	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0031048	chromatin silencing by small RNA(GO:0031048)
0.0	1.6	GO:0007492	endoderm development(GO:0007492)
0.0	0.1	GO:0040033	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.2	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0006843	mitochondrial citrate transport(GO:0006843)
0.0	0.3	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0048387	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.7	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.2	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.0	GO:1901207	regulation of heart looping(GO:1901207)
0.0	0.2	GO:2000273	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.2	GO:0001881	receptor recycling(GO:0001881)
0.0	3.7	GO:0006364	rRNA processing(GO:0006364)
0.0	0.3	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.3	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0033292	T-tubule organization(GO:0033292)
0.0	0.5	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.3	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.9	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.9	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
0.0	0.1	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.0	0.2	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.1	GO:0000706	meiotic DNA double-strand break processing(GO:0000706)
0.0	0.1	GO:0010991	SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0097355	protein localization to heterochromatin(GO:0097355)
0.0	0.1	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.4	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.2	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0	0.1	GO:0051352	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	0.7	GO:0006006	glucose metabolic process(GO:0006006)
0.0	0.8	GO:0006900	membrane budding(GO:0006900)
0.0	0.4	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	1.0	GO:0097191	extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0009410	response to xenobiotic stimulus(GO:0009410)
0.0	0.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.6	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.2	GO:0050909	sensory perception of taste(GO:0050909)
0.0	4.2	GO:0009116	nucleoside metabolic process(GO:0009116)
0.0	0.5	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.3	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.2	GO:0048538	thymus development(GO:0048538)
0.0	0.3	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	1.0	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0035776	pronephric proximal tubule development(GO:0035776)
0.0	0.2	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.1	GO:0000338	protein deneddylation(GO:0000338)
0.0	1.6	GO:0008033	tRNA processing(GO:0008033)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.3	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.5	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	2.7	GO:0006914	autophagy(GO:0006914)
0.0	0.1	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.0	0.6	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.5	GO:0010952	positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0	0.9	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.1	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.4	GO:0051781	positive regulation of cell division(GO:0051781)
0.0	0.4	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.7	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.3	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.1	GO:0036368	cone photoresponse recovery(GO:0036368)
0.0	0.1	GO:0051231	mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0	0.2	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.2	GO:0044773	mitotic DNA damage checkpoint(GO:0044773)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	1.0	GO:0045930	negative regulation of mitotic cell cycle(GO:0045930)
0.0	0.2	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.2	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0072676	lymphocyte migration(GO:0072676)
0.0	0.7	GO:0007602	phototransduction(GO:0007602)
0.0	0.7	GO:0003341	cilium movement(GO:0003341)
0.0	0.1	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	12.8	GO:0006508	proteolysis(GO:0006508)
0.0	0.1	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.4	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0	0.1	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.0	0.0	GO:0072387	FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0	0.1	GO:0010828	positive regulation of glucose transport(GO:0010828)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.3	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0000726	non-recombinational repair(GO:0000726)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	0.8	GO:0033391	chromatoid body(GO:0033391)
0.7	3.5	GO:0005797	Golgi medial cisterna(GO:0005797)
0.6	1.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.5	6.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.5	1.8	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.4	6.6	GO:0030315	T-tubule(GO:0030315)
0.4	3.1	GO:0032019	mitochondrial cloud(GO:0032019)
0.3	1.3	GO:0031511	Mis6-Sim4 complex(GO:0031511)
0.3	5.9	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.3	5.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3	3.9	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.3	1.0	GO:0043073	germ cell nucleus(GO:0043073)
0.2	0.6	GO:0005948	acetolactate synthase complex(GO:0005948)
0.2	0.7	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	3.1	GO:0042555	MCM complex(GO:0042555)
0.2	20.8	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2	2.9	GO:0030057	desmosome(GO:0030057)
0.2	0.5	GO:0098536	deuterosome(GO:0098536)
0.2	1.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	2.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.6	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.1	8.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	0.4	GO:0043614	multi-eIF complex(GO:0043614)
0.1	2.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.9	GO:0097225	sperm midpiece(GO:0097225)
0.1	9.2	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1	1.5	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	0.3	GO:0031166	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1	0.6	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.3	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1	0.4	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	0.4	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	1.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.4	GO:0032433	filopodium tip(GO:0032433)
0.1	9.3	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	1.4	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	4.1	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.7	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	0.4	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	0.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.4	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.1	0.3	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.9	GO:0036157	outer dynein arm(GO:0036157)
0.1	4.6	GO:0031901	early endosome membrane(GO:0031901)
0.1	1.0	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1	0.6	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1	5.9	GO:0005871	kinesin complex(GO:0005871)
0.1	0.7	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.9	GO:0098827	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1	1.3	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.9	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	1.9	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.5	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1	0.2	GO:0044609	DBIRD complex(GO:0044609)
0.1	0.4	GO:0001650	fibrillar center(GO:0001650)
0.0	0.7	GO:0070187	telosome(GO:0070187)
0.0	5.3	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.5	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.9	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	3.3	GO:0055037	recycling endosome(GO:0055037)
0.0	1.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.5	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	8.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.4	GO:0031526	brush border membrane(GO:0031526)
0.0	0.2	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.3	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.4	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.6	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.7	GO:0097546	ciliary base(GO:0097546)
0.0	0.5	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.2	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	1.9	GO:0031228	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0	0.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.3	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0	0.2	GO:0031261	DNA replication preinitiation complex(GO:0031261)
0.0	10.1	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.2	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.4	GO:0005839	proteasome core complex(GO:0005839)
0.0	1.2	GO:0010008	endosome membrane(GO:0010008)
0.0	0.8	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.6	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0030662	coated vesicle membrane(GO:0030662)
0.0	0.1	GO:0070390	transcription export complex 2(GO:0070390)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.3	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0033557	Slx1-Slx4 complex(GO:0033557)
0.0	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.4	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.7	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	10.1	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.5	GO:0043186	P granule(GO:0043186)
0.0	1.9	GO:0005770	late endosome(GO:0005770)
0.0	0.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.4	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	17.0	GO:0005615	extracellular space(GO:0005615)
0.0	0.7	GO:0030286	dynein complex(GO:0030286)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.0	0.9	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.2	GO:0080132	fatty acid alpha-hydroxylase activity(GO:0080132)
1.3	3.9	GO:0034185	apolipoprotein binding(GO:0034185)
1.3	11.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
1.3	3.8	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.2	7.4	GO:0032052	bile acid binding(GO:0032052)
0.8	2.4	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.8	3.0	GO:0004155	6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.7	12.5	GO:0032190	acrosin binding(GO:0032190)
0.7	4.4	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.7	2.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6	1.8	GO:0001729	ceramide kinase activity(GO:0001729)
0.6	1.8	GO:0070905	glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.6	2.9	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.6	4.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.5	4.8	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.5	4.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5	4.4	GO:0005113	patched binding(GO:0005113)
0.5	2.4	GO:0004122	cystathionine beta-synthase activity(GO:0004122)
0.5	1.8	GO:0004478	methionine adenosyltransferase activity(GO:0004478)
0.4	1.2	GO:0003978	UDP-glucose 4-epimerase activity(GO:0003978)
0.3	1.7	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3	1.0	GO:0042806	fucose binding(GO:0042806)
0.3	4.3	GO:0070697	activin receptor binding(GO:0070697)
0.3	3.2	GO:0016936	galactoside binding(GO:0016936)
0.3	2.9	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3	2.9	GO:0004359	glutaminase activity(GO:0004359)
0.3	1.2	GO:0004772	sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.3	1.5	GO:0019960	C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3	1.5	GO:0004645	phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3	1.2	GO:0051139	calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.3	2.0	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.3	7.9	GO:0008483	transaminase activity(GO:0008483)
0.3	0.8	GO:0016713	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3	2.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.3	6.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.3	1.0	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3	0.8	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2	1.9	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2	1.4	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.2	2.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2	3.0	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	1.8	GO:0015232	heme transporter activity(GO:0015232)
0.2	4.4	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	2.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	1.9	GO:0004096	catalase activity(GO:0004096)
0.2	4.2	GO:0003785	actin monomer binding(GO:0003785)
0.2	1.0	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2	1.2	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2	1.9	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.2	1.5	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	3.2	GO:0061608	nuclear import signal receptor activity(GO:0061608)
0.2	0.6	GO:0003984	acetolactate synthase activity(GO:0003984)
0.2	0.9	GO:0001223	transcription coactivator binding(GO:0001223)
0.2	0.9	GO:0008097	5S rRNA binding(GO:0008097)
0.2	1.8	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.2	2.1	GO:0008422	beta-glucosidase activity(GO:0008422)
0.2	0.9	GO:0046592	polyamine oxidase activity(GO:0046592)
0.2	0.7	GO:0003844	1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.2	1.2	GO:0000254	C-4 methylsterol oxidase activity(GO:0000254)
0.2	0.7	GO:0015227	acyl carnitine transmembrane transporter activity(GO:0015227)
0.2	3.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	3.4	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2	1.9	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.2	1.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	2.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.2	0.6	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.2	0.3	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.1	2.6	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	1.3	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1	1.3	GO:0035925	AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.4	GO:0032574	5'-3' RNA helicase activity(GO:0032574)
0.1	0.7	GO:0038132	neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1	0.6	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1	0.6	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.7	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.4	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.9	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	3.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	1.8	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	1.9	GO:2001069	glycogen binding(GO:2001069)
0.1	5.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.7	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	1.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	1.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.1	0.5	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1	1.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	12.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.6	GO:0008187	poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.1	3.7	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	3.9	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	3.6	GO:0003951	NAD+ kinase activity(GO:0003951)
0.1	0.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.8	GO:1903924	estradiol binding(GO:1903924)
0.1	0.6	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.5	GO:1902388	ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1	0.9	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1	1.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	1.0	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.4	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.1	3.9	GO:0004180	carboxypeptidase activity(GO:0004180)
0.1	0.3	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1	0.6	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	1.1	GO:0043495	protein anchor(GO:0043495)
0.1	0.5	GO:0004001	adenosine kinase activity(GO:0004001)
0.1	0.4	GO:0004903	growth hormone receptor activity(GO:0004903)
0.1	6.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	1.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	2.9	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	0.8	GO:0048039	ubiquinone binding(GO:0048039)
0.1	1.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.3	GO:1990699	palmitoleyl hydrolase activity(GO:1990699)
0.1	0.7	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	1.4	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.1	2.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.5	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.6	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	4.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	1.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.4	GO:0090554	phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1	0.4	GO:0031769	glucagon receptor binding(GO:0031769)
0.1	0.8	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	17.4	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	5.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	0.3	GO:0005461	UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1	2.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.9	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.2	GO:0005183	gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1	4.7	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	0.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	1.3	GO:0051393	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1	1.1	GO:0004382	guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1	0.5	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.1	0.2	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	3.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	1.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	2.4	GO:0019843	rRNA binding(GO:0019843)
0.1	0.4	GO:0070888	E-box binding(GO:0070888)
0.1	0.2	GO:1990174	m7G(5')pppN diphosphatase activity(GO:0050072) phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1	0.8	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.1	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	0.5	GO:0034452	dynactin binding(GO:0034452)
0.1	0.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	0.2	GO:0004925	prolactin receptor activity(GO:0004925)
0.1	0.9	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1	1.5	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1	0.2	GO:0070224	sulfide:quinone oxidoreductase activity(GO:0070224)
0.1	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1	4.8	GO:0003777	microtubule motor activity(GO:0003777)
0.1	0.3	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1	0.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	1.6	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.1	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	0.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	2.0	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1	0.2	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1	1.0	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	0.2	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.1	0.3	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.4	GO:0072518	Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0	0.3	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	1.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.7	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.3	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	7.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	10.7	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	2.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.2	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0	0.9	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.5	GO:0004549	ribonuclease P activity(GO:0004526) tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.5	GO:0030172	troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0	1.8	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0035197	siRNA binding(GO:0035197)
0.0	6.3	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.9	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	1.5	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.2	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.4	GO:0005223	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.8	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	1.9	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.2	GO:0019202	amino acid kinase activity(GO:0019202)
0.0	0.4	GO:0015385	monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.5	GO:0031729	CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.4	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.4	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.5	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0002020	protease binding(GO:0002020)
0.0	0.4	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.9	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	2.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.2	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.1	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0	0.1	GO:0050254	rhodopsin kinase activity(GO:0050254)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	1.4	GO:0042562	hormone binding(GO:0042562)
0.0	0.7	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.4	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.0	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.7	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.9	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	3.4	GO:0004386	helicase activity(GO:0004386)
0.0	0.1	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	1.2	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0052794	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	1.3	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	0.4	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.2	GO:0070122	isopeptidase activity(GO:0070122)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.3	GO:0045159	myosin II binding(GO:0045159)
0.0	1.4	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	1.1	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.2	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738)
0.0	0.1	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.4	GO:0031267	small GTPase binding(GO:0031267)
0.0	1.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.4	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0072571	ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.4	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0	0.1	GO:0008506	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.7	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	1.5	GO:0042803	protein homodimerization activity(GO:0042803)
0.0	0.7	GO:0032934	sterol binding(GO:0032934)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0016779	nucleotidyltransferase activity(GO:0016779)
0.0	0.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.2	GO:0009055	electron carrier activity(GO:0009055)
0.0	0.3	GO:0015377	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	10.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	4.7	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	0.8	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	4.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	0.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	3.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	2.0	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	0.7	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	0.4	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	2.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	2.7	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	1.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	0.6	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	1.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.7	PID BMP PATHWAY	BMP receptor signaling
0.1	0.9	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	3.0	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	0.4	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	1.9	PID FOXO PATHWAY	FoxO family signaling
0.1	0.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	0.6	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	1.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	1.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	2.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.8	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.6	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.9	PID E2F PATHWAY	E2F transcription factor network
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.8	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	PID WNT SIGNALING PATHWAY	Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	9.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
1.0	3.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7	3.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.7	6.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6	1.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4	4.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.4	2.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	3.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.3	1.9	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	4.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.2	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2	1.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	5.0	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.2	2.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	1.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.6	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	2.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	4.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.0	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	9.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	1.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	2.8	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	0.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	3.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	2.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	1.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	3.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.4	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.7	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	4.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.7	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination

Results for TCF4_id4_mespaa+mespab+mespba+mespbb

Z-value: 0.95

Motif logo

Transcription factors associated with TCF4_id4_mespaa+mespab+mespba+mespbb

Activity-expression correlation:

Activity profile of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Sorted Z-values of TCF4_id4_mespaa+mespab+mespba+mespbb motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF4_id4_mespaa+mespab+mespba+mespbb

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: