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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for barx1

Z-value: 0.78

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Transcription factors associated with barx1

Gene Symbol Gene ID Gene Info
ENSDARG00000007407 BARX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barx1dr11_v1_chr11_+_27543093_27543093-0.075.2e-01Click!

Activity profile of barx1 motif

Sorted Z-values of barx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31276842 11.68 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr5_+_32206378 7.26 ENSDART00000126873
ENSDART00000051361
myosin, heavy polypeptide 2, fast muscle specific
chr5_+_2815021 6.25 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr23_+_20422661 5.88 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr25_+_35019693 5.49 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr20_+_15015557 4.88 ENSDART00000039345
myocilin
chr3_-_18030938 4.84 ENSDART00000013540
si:ch73-141c7.1
chr22_-_31060579 4.77 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr23_+_409578 4.50 ENSDART00000008177
solute carrier family 25, member 55b
chr25_+_20089986 4.46 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr7_+_41295974 3.87 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
chr16_-_38118003 3.84 ENSDART00000058667
si:dkey-23o4.6
chr4_+_2252123 3.67 ENSDART00000163996
ENSDART00000066491
GLI pathogenesis-related 1a
chr17_+_29276544 3.62 ENSDART00000049399
ankyrin repeat domain 9
chr25_+_13620555 3.59 ENSDART00000163642
si:ch211-172l8.4
chr7_+_20471315 3.55 ENSDART00000173714
si:dkey-19b23.13
chr16_-_25608453 3.52 ENSDART00000140140
zgc:110410
chr12_+_48216662 3.41 ENSDART00000187369
leucine rich repeat containing 20
chr5_-_41531629 3.38 ENSDART00000051082
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr9_-_9980704 3.37 ENSDART00000130243
ENSDART00000193475
UDP glucuronosyltransferase 1 family a, b
chr22_+_12770877 3.32 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr3_+_59851537 3.30 ENSDART00000180997

chr24_+_21622373 3.18 ENSDART00000183611
ribosomal protein L21
chr8_-_18537866 3.18 ENSDART00000148802
ENSDART00000148962
ENSDART00000149506
nexilin (F actin binding protein)
chr25_+_10811551 3.04 ENSDART00000167730
alanyl (membrane) aminopeptidase b
chr15_+_32711663 2.98 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr11_-_17981421 2.94 ENSDART00000005999
ENSDART00000104046
twinfilin actin-binding protein 2b
chr13_+_7442023 2.92 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr19_-_40199081 2.91 ENSDART00000051970
ENSDART00000151079
granulin 2
chr6_-_54180699 2.88 ENSDART00000045901
ribosomal protein S10
chr21_-_5881344 2.88 ENSDART00000009241
ribosomal protein L35
chr19_-_11315224 2.87 ENSDART00000104933
endonuclease/exonuclease/phosphatase family domain containing 1
chr18_+_5490668 2.83 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr3_-_61205711 2.78 ENSDART00000055062
parvalbumin 1
chr3_-_45848257 2.75 ENSDART00000147198
insulin-like growth factor binding protein, acid labile subunit
chr14_+_923803 2.75 ENSDART00000111141
myozenin 3a
chr9_+_24088062 2.75 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr24_+_28614576 2.70 ENSDART00000184941
ATP-binding cassette, sub-family A (ABC1), member 4a
chr1_-_12027 2.67 ENSDART00000164359
ribosomal protein L24
chr4_+_76575585 2.65 ENSDART00000131588
membrane-spanning 4-domains, subfamily A, member 17A.11
chr3_-_45848043 2.65 ENSDART00000055132
insulin-like growth factor binding protein, acid labile subunit
chr16_-_26537103 2.64 ENSDART00000134908
ENSDART00000008152
serum/glucocorticoid regulated kinase 2b
chr22_-_18779232 2.54 ENSDART00000186726
ATP synthase F1 subunit delta
chr18_+_26719787 2.51 ENSDART00000141672
alpha-kinase 3a
chr14_-_970853 2.50 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr1_-_53714885 2.50 ENSDART00000026409
chaperonin containing TCP1, subunit 4 (delta)
chr21_+_26071874 2.50 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr13_-_37615029 2.45 ENSDART00000111199
si:dkey-188i13.6
chr16_+_12836143 2.44 ENSDART00000067741
calcium channel, voltage-dependent, gamma subunit 6b
chr12_+_48220584 2.43 ENSDART00000164392
leucine rich repeat containing 20
chr14_+_15622817 2.41 ENSDART00000158624
si:dkey-203a12.9
chr7_+_29954709 2.39 ENSDART00000173904
alpha-tropomyosin
chr1_-_43684584 2.37 ENSDART00000074609
succinate-CoA ligase, alpha subunit
chr6_+_39290777 2.35 ENSDART00000155700
si:dkey-195m11.11
chr24_-_38110779 2.35 ENSDART00000147783
c-reactive protein, pentraxin-related
chr21_-_19316985 2.35 ENSDART00000141596
glycerol-3-phosphate acyltransferase 3
chr14_+_46313396 2.34 ENSDART00000047525
crystallin, beta A1, like 1
chr3_+_442570 2.32 ENSDART00000058099
si:ch73-308m11.1
chr21_-_1635268 2.29 ENSDART00000151258
zgc:152948
chr4_+_391297 2.29 ENSDART00000030215
ribosomal protein L18a
chr11_-_22303678 2.28 ENSDART00000159527
ENSDART00000159681
transcription factor EB
chr2_-_57837838 2.28 ENSDART00000010699
splicing factor 3a, subunit 2
chr8_-_45279411 2.28 ENSDART00000175207
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr24_-_32582880 2.28 ENSDART00000186307
retinol dehydrogenase 12, like
chr14_-_11456724 2.27 ENSDART00000110424
si:ch211-153b23.4
chr22_+_10651726 2.27 ENSDART00000145459
Ras association (RalGDS/AF-6) domain family 1
chr10_+_33382858 2.27 ENSDART00000063662
malate dehydrogenase 2, NAD (mitochondrial)
chr16_-_41762983 2.26 ENSDART00000192936
si:dkey-199f5.8
chr16_+_16977786 2.25 ENSDART00000043173
ENSDART00000132150
ribosomal protein L18
chr22_+_1170294 2.24 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr22_-_24818066 2.24 ENSDART00000143443
vitellogenin 6
chr22_-_36876133 2.23 ENSDART00000147006
kininogen 1
chr17_+_4030493 2.20 ENSDART00000151849
hydroxyacid oxidase (glycolate oxidase) 1
chr13_-_4223955 2.16 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr19_-_657439 2.13 ENSDART00000167100
solute carrier family 6 (neutral amino acid transporter), member 18
chr4_-_75175407 2.12 ENSDART00000180125

chr7_+_27603211 2.11 ENSDART00000148782
cytochrome P450, family 2, subfamily R, polypeptide 1
chr3_-_29870848 2.11 ENSDART00000186457
ribosomal protein L3
chr1_-_513762 2.10 ENSDART00000148162
ENSDART00000144606
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr25_+_186583 2.09 ENSDART00000161504
PCNA clamp associated factor
chr11_+_13224281 2.09 ENSDART00000102557
ENSDART00000178706
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr10_+_9410304 2.07 ENSDART00000080843
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr16_+_31921812 2.07 ENSDART00000176928
ENSDART00000193733
ribosomal protein S9
chr22_+_15315655 2.06 ENSDART00000141249
sulfotransferase family 3, cytosolic sulfotransferase 3
chr3_+_24640946 2.05 ENSDART00000123994
ENSDART00000126230
zgc:113411
chr25_-_22187397 2.05 ENSDART00000123211
ENSDART00000139110
plakophilin 3a
chr9_+_28598577 2.03 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
chr17_+_8799451 2.02 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr16_+_19637384 2.02 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr16_+_13965923 2.01 ENSDART00000103857
zgc:162509
chr14_+_46313135 2.01 ENSDART00000172902
crystallin, beta A1, like 1
chr3_+_26081343 2.00 ENSDART00000134647
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr17_-_7792376 2.00 ENSDART00000064655
zinc finger and BTB domain containing 2a
chr2_-_37098785 1.99 ENSDART00000003670
zgc:101744
chr23_-_19682971 1.98 ENSDART00000048891
zgc:193598
chr2_+_54641644 1.98 ENSDART00000027313
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr23_-_5719453 1.98 ENSDART00000033093
ladinin
chr22_+_3153876 1.92 ENSDART00000163327
ribosomal protein L36
chr22_-_18778988 1.92 ENSDART00000019235
ATP synthase F1 subunit delta
chr17_+_30843881 1.92 ENSDART00000149600
ENSDART00000148547
tripeptidyl peptidase I
chr13_-_17723417 1.90 ENSDART00000183834
voltage-dependent anion channel 2
chr19_+_4139065 1.90 ENSDART00000172524
si:dkey-218f9.10
chr4_-_19884440 1.87 ENSDART00000182979
ENSDART00000105967
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr4_-_17785120 1.86 ENSDART00000024775
myosin binding protein C, slow type
chr9_-_42484444 1.86 ENSDART00000048320
ENSDART00000047653
tissue factor pathway inhibitor a
chr10_+_40633990 1.85 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
chr7_-_16562200 1.84 ENSDART00000169093
ENSDART00000173491
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr16_+_16968682 1.84 ENSDART00000111074
si:ch211-120k19.1
chr14_+_15430991 1.82 ENSDART00000158221
si:dkey-203a12.5
chr20_+_38276690 1.80 ENSDART00000061437
chemokine (C-C motif) ligand 38, duplicate 6
chr24_+_35387517 1.78 ENSDART00000058571
snail family zinc finger 2
chr11_+_41838801 1.76 ENSDART00000014871
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr8_+_47099033 1.75 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr1_-_21287724 1.75 ENSDART00000193900
neuropeptide Y receptor Y1
chr21_-_11575626 1.73 ENSDART00000133171
calpastatin
chr20_-_46534179 1.73 ENSDART00000060689
eukaryotic translation initiation factor 2B, subunit 2 beta
chr24_-_20926812 1.72 ENSDART00000130958
coiled-coil domain containing 58
chr20_+_26556372 1.71 ENSDART00000187179
ENSDART00000157291
interferon regulatory factor 4b
chr18_-_22713402 1.70 ENSDART00000145871
si:ch73-113g13.2
chr3_+_21225750 1.69 ENSDART00000139213
zgc:153968
chr15_-_42206890 1.68 ENSDART00000015843
paired box 3b
chr25_-_18435481 1.68 ENSDART00000004771
POC1 centriolar protein B
chr15_-_43287515 1.67 ENSDART00000155103
protease, serine, 16 (thymus)
chr5_+_72137331 1.66 ENSDART00000149195
exosome component 2
chr14_-_26536504 1.66 ENSDART00000105933
transforming growth factor, beta-induced
chr4_-_12477224 1.65 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr17_+_8799661 1.65 ENSDART00000105326
tonsoku-like, DNA repair protein
chr18_-_22713621 1.64 ENSDART00000079013
si:ch73-113g13.2
chr3_+_17537352 1.64 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr16_+_29509133 1.63 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr12_-_26423439 1.63 ENSDART00000113978
synaptopodin 2-like b
chr9_+_6587364 1.63 ENSDART00000122279
four and a half LIM domains 2a
chr17_+_21452258 1.61 ENSDART00000157098
phospholipase A2, group IVF, tandem duplicate 1
chr4_-_992063 1.60 ENSDART00000181630
ENSDART00000183898
ENSDART00000160902
N-acetylgalactosaminidase, alpha
chr8_+_42718135 1.60 ENSDART00000158900
zgc:194007
chr11_-_2131280 1.59 ENSDART00000008409
calcium binding and coiled-coil domain 1b
chr1_-_6028876 1.59 ENSDART00000168117
si:ch1073-345a8.1
chr6_-_54180516 1.58 ENSDART00000149945
ribosomal protein S10
chr5_+_27897504 1.58 ENSDART00000130936
ADAM metallopeptidase domain 28
chr16_+_41974438 1.58 ENSDART00000102771
si:ch211-225p5.8
chr11_+_42585138 1.58 ENSDART00000019008
ankyrin repeat and SOCS box containing 14a
chr13_-_52089003 1.57 ENSDART00000187600
transmembrane protein 254
chr13_+_35637048 1.57 ENSDART00000085037
thrombospondin 2a
chr12_+_30563550 1.56 ENSDART00000126064
si:ch211-28p3.4
chr24_+_35933869 1.56 ENSDART00000173322
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b
chr6_+_13207139 1.55 ENSDART00000185601
ENSDART00000182182
INO80 complex subunit Db
chr3_-_8272632 1.54 ENSDART00000143522
cytochrome P450, family 2, subfamily K, polypeptide 6
chr10_+_40742685 1.54 ENSDART00000184858
ENSDART00000140300
trace amine associated receptor 19e
chr15_+_46313082 1.54 ENSDART00000153830
si:ch1073-190k2.1
chr4_+_76705830 1.54 ENSDART00000064312
membrane-spanning 4-domains, subfamily A, member 17A.7
chr6_+_34028532 1.53 ENSDART00000155827
si:ch73-185c24.2
chr6_+_13206516 1.53 ENSDART00000036927
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr25_+_10909850 1.53 ENSDART00000186021

chr10_+_40756352 1.53 ENSDART00000156210
ENSDART00000144576
trace amine associated receptor 19f
chr22_-_1168291 1.52 ENSDART00000167724
si:ch1073-181h11.4
chr19_+_627899 1.52 ENSDART00000148508
telomerase reverse transcriptase
chr20_+_38279523 1.52 ENSDART00000061311
chemokine (C-C motif) ligand 38, duplicate 5
chr8_-_38616712 1.52 ENSDART00000141827
si:ch211-198d23.1
chr17_+_25849332 1.51 ENSDART00000191994
acyl-CoA synthetase short chain family member 1
chr17_+_23730089 1.51 ENSDART00000034913
zgc:91976
chr3_-_29899172 1.51 ENSDART00000140518
ENSDART00000020311
ribosomal protein L27
chr21_+_5472330 1.50 ENSDART00000157533
lymphocyte antigen 6 family member M2
chr1_-_614583 1.49 ENSDART00000004062
ENSDART00000147937
ENSDART00000146351
ENSDART00000134456
ATP synthase peripheral stalk subunit F6
chr4_+_21717793 1.49 ENSDART00000040266
myogenic factor 6
chr10_-_40454685 1.49 ENSDART00000137832
trace amine associated receptor 20o
chr20_-_22778394 1.48 ENSDART00000152645
FIP1 like 1a (S. cerevisiae)
chr12_+_47663419 1.48 ENSDART00000171932
hematopoietically expressed homeobox
chr6_-_46861676 1.48 ENSDART00000188712
ENSDART00000190148
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr19_+_20778011 1.47 ENSDART00000024208
nuclear transport factor 2, like
chr7_+_27251376 1.47 ENSDART00000173521
ENSDART00000173962
SRY (sex determining region Y)-box 6
chr24_-_30275735 1.47 ENSDART00000168723
sorting nexin 7
chr7_+_4474880 1.47 ENSDART00000143528
si:dkey-83f18.14
chr3_-_40965328 1.46 ENSDART00000102393
cytochrome P450, family 3, subfamily c, polypeptide 2
chr1_-_17735861 1.46 ENSDART00000018238
PDZ and LIM domain 3a
chr1_-_49250490 1.46 ENSDART00000150386
si:ch73-6k14.2
chr11_+_20896122 1.46 ENSDART00000162339
ENSDART00000181111

chr9_+_21306902 1.45 ENSDART00000138554
ENSDART00000004108
exportin 4
chr3_-_26122353 1.45 ENSDART00000111042
ENSDART00000161427
heat shock cognate 70-kd protein, tandem duplicate 2
chr19_+_41169996 1.44 ENSDART00000048438
ankyrin repeat and SOCS box containing 4
chr20_+_53441935 1.44 ENSDART00000175214
apolipoprotein Bb, tandem duplicate 2
chr15_+_38018301 1.44 ENSDART00000114188
ENSDART00000171150
si:ch73-380l3.1
chr17_-_21884323 1.43 ENSDART00000155574
CUB and zona pellucida-like domains 1, tandem duplicate 1
chr22_-_17631675 1.43 ENSDART00000132565
histocompatibility (minor) HA-1 b
chr16_+_40563533 1.43 ENSDART00000190368
tumor protein p53 inducible nuclear protein 1
chr8_-_39739056 1.43 ENSDART00000147992
si:ch211-170d8.5
chr25_-_28926631 1.43 ENSDART00000112850
electron transfer flavoprotein beta subunit lysine methyltransferase
chr16_-_27566552 1.42 ENSDART00000142102
zgc:153215
chr8_-_31062811 1.42 ENSDART00000142528
solute carrier family 20, member 1a
chr15_+_14165474 1.41 ENSDART00000161891
ENSDART00000159757
chloride channel accessory 5, tandem duplicate 2
chr17_-_30652738 1.41 ENSDART00000154960
SH3 and SYLF domain containing 1
chr25_-_37465064 1.39 ENSDART00000186128
zgc:158366
chr1_-_23293261 1.39 ENSDART00000122648
UDP-glucose 6-dehydrogenase
chr3_-_1970820 1.39 ENSDART00000136467
si:ch211-254c8.3
chr10_+_10313024 1.39 ENSDART00000142895
ENSDART00000129952
ubiquitin related modifier 1
chr3_-_32275975 1.38 ENSDART00000178448
carnitine palmitoyltransferase 1Cb
chr12_+_13319132 1.37 ENSDART00000049167
proteasome activator subunit 2
chr22_-_23706771 1.37 ENSDART00000159771
complement factor H like 1
chr4_+_16323970 1.37 ENSDART00000190651

chr16_+_48682309 1.37 ENSDART00000183957
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_+_33894396 1.37 ENSDART00000130853
ENSDART00000152988
major facilitator superfamily domain containing 13A

Network of associatons between targets according to the STRING database.

First level regulatory network of barx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0010265 SCF complex assembly(GO:0010265)
1.1 3.3 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.0 6.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.9 2.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.7 2.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.7 13.1 GO:0014823 response to activity(GO:0014823)
0.6 3.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.6 5.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.6 1.2 GO:0046385 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.6 2.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.6 1.7 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.6 1.7 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.5 2.2 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.5 2.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.5 2.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.5 1.5 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.5 1.5 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.5 2.0 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.5 1.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.5 2.4 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.5 1.8 GO:0035994 response to muscle stretch(GO:0035994)
0.5 4.5 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.4 2.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.4 4.1 GO:0051601 exocyst localization(GO:0051601)
0.4 1.6 GO:0042755 eating behavior(GO:0042755)
0.4 2.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.4 16.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 1.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.4 2.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 2.1 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.3 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 0.7 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.3 1.4 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3 1.7 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 2.0 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.3 1.0 GO:0036076 ligamentous ossification(GO:0036076)
0.3 2.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.3 1.3 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.3 2.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 5.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 0.8 GO:0030237 female sex determination(GO:0030237)
0.3 1.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 0.8 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 1.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.3 0.8 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.3 2.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.3 4.6 GO:0016203 muscle attachment(GO:0016203)
0.3 1.5 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.3 0.8 GO:0055057 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.2 1.7 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 0.7 GO:2000379 positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 4.8 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 5.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 5.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 3.9 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.2 1.2 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 1.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 1.4 GO:0032447 protein urmylation(GO:0032447)
0.2 1.6 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.2 2.3 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.9 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 1.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.2 0.9 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.2 4.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.3 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.2 1.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 0.8 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.2 1.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.2 2.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.2 0.6 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.2 1.4 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.2 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.2 1.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 4.0 GO:0031297 replication fork processing(GO:0031297)
0.2 1.3 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.2 1.3 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.2 0.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.2 1.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.2 1.2 GO:0034650 glucocorticoid biosynthetic process(GO:0006704) cortisol metabolic process(GO:0034650)
0.2 1.7 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 1.0 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.2 2.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 1.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.2 GO:0021661 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.2 0.7 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.2 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 0.8 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.2 0.5 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.2 1.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 2.1 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.6 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 2.3 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.9 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.9 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 1.4 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 2.7 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.1 1.0 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 2.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.7 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.4 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.3 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 2.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.7 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0003156 regulation of organ formation(GO:0003156)
0.1 0.8 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.1 3.1 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.9 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1 1.2 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.0 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 2.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 2.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.4 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.1 3.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.5 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 2.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.4 GO:0042026 protein refolding(GO:0042026)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.7 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.1 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.3 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 2.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.8 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 1.3 GO:0009651 response to salt stress(GO:0009651)
0.1 0.4 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 0.3 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 1.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 2.2 GO:0032355 response to estradiol(GO:0032355)
0.1 0.3 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.2 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.3 GO:0090398 cellular senescence(GO:0090398)
0.1 4.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 2.1 GO:0051923 sulfation(GO:0051923)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.2 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.1 1.3 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.5 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 2.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 1.1 GO:0015908 fatty acid transport(GO:0015908)
0.1 0.3 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.1 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 1.3 GO:0070672 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.1 1.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.8 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.3 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.5 GO:0032196 transposition(GO:0032196)
0.1 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 0.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.6 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 0.3 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.7 GO:0007099 centriole replication(GO:0007099)
0.1 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.2 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 0.5 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.4 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.6 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.5 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.4 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 4.3 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.3 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 1.3 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.6 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 3.3 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.8 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 3.0 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.6 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.5 GO:0042509 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 2.5 GO:0007416 synapse assembly(GO:0007416)
0.0 2.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 3.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.8 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.4 GO:0045162 neuronal ion channel clustering(GO:0045161) clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.9 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.5 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.9 GO:0007596 blood coagulation(GO:0007596)
0.0 1.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.6 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 2.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.0 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.6 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.7 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.7 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.0 1.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.0 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.0 0.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 1.5 GO:0097530 granulocyte migration(GO:0097530) neutrophil migration(GO:1990266)
0.0 1.1 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.2 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.5 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0030534 adult behavior(GO:0030534)
0.0 0.3 GO:0046464 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 2.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 2.9 GO:0009617 response to bacterium(GO:0009617)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.2 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.6 GO:0048840 otolith development(GO:0048840)
0.0 0.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 1.4 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 1.0 GO:0006400 tRNA modification(GO:0006400)
0.0 4.6 GO:0006412 translation(GO:0006412)
0.0 0.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.4 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.5 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.9 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 4.4 GO:0060548 negative regulation of cell death(GO:0060548)
0.0 0.6 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
1.1 3.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.6 4.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.5 3.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.5 22.0 GO:0005861 troponin complex(GO:0005861)
0.5 1.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.5 1.5 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.5 2.0 GO:0031673 H zone(GO:0031673)
0.4 1.2 GO:0034515 proteasome storage granule(GO:0034515)
0.4 1.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.3 20.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 3.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.4 GO:0034359 mature chylomicron(GO:0034359)
0.3 1.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.3 1.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.3 2.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 1.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 0.7 GO:0034457 Mpp10 complex(GO:0034457)
0.2 3.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 0.8 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 1.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.7 GO:0097519 DNA recombinase complex(GO:0097519)
0.2 1.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 7.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 15.0 GO:0030018 Z disc(GO:0030018)
0.1 3.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.9 GO:0030914 STAGA complex(GO:0030914)
0.1 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.0 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.3 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 2.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 4.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 1.6 GO:0031430 M band(GO:0031430)
0.1 9.8 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 1.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 3.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.2 GO:0097541 axonemal basal plate(GO:0097541)
0.1 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 5.4 GO:0005884 actin filament(GO:0005884)
0.1 2.8 GO:0005643 nuclear pore(GO:0005643)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.7 GO:0002102 podosome(GO:0002102)
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)
0.1 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 3.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 6.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 2.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 7.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 11.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 5.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.6 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 2.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.5 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 8.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.7 GO:0042383 sarcolemma(GO:0042383)
0.0 0.6 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 3.7 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
1.1 3.3 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.8 3.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.7 3.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5 4.8 GO:0048039 ubiquinone binding(GO:0048039)
0.5 1.6 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.5 2.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.5 2.1 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.5 1.5 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.5 2.8 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 2.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.4 1.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.4 3.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 4.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 1.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.4 2.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 1.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.4 4.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 1.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.4 25.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.4 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.3 1.0 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.3 2.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.3 1.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.3 0.9 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.3 1.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.3 2.7 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 1.4 GO:0015440 peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
0.3 1.4 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.3 1.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 2.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 1.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 1.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.2 2.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.9 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.2 0.6 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.2 5.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 1.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.2 0.8 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.5 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.2 1.7 GO:0048038 quinone binding(GO:0048038)
0.2 0.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 1.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.7 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.2 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.8 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.2 30.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 1.2 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 3.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 2.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.8 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.1 0.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 4.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.9 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 2.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 3.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.4 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.8 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.3 GO:0042923 neuropeptide binding(GO:0042923)
0.1 2.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 2.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 1.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.1 GO:0010181 FMN binding(GO:0010181)
0.1 2.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 3.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 7.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 0.8 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.9 GO:0030332 cyclin binding(GO:0030332)
0.1 1.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 2.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.2 GO:0002020 protease binding(GO:0002020)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.6 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 3.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 4.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.3 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 0.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.4 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 2.8 GO:0000049 tRNA binding(GO:0000049)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 5.1 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 3.1 GO:0008009 chemokine activity(GO:0008009)
0.1 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 3.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.8 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 2.6 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 1.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 2.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.5 GO:0032934 sterol binding(GO:0032934)
0.0 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.9 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 12.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 6.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0005496 steroid binding(GO:0005496)
0.0 0.5 GO:0051020 GTPase binding(GO:0051020)
0.0 2.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 3.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 5.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 2.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 7.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 1.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 3.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 7.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 5.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 28.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 1.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 3.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 2.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 1.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 3.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 6.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 2.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 4.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 4.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 2.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.7 REACTOME TRANSLATION Genes involved in Translation
0.1 2.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.0 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 4.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A