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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for bhlhe40

Z-value: 0.56

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Transcription factors associated with bhlhe40

Gene Symbol Gene ID Gene Info
bhlhe40
ENSDARG00000004060 basic helix-loop-helix family, member e40

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
bhlhe40dr11_v1_chr11_-_35763323_35763323-0.028.5e-01Click!

Activity profile of bhlhe40 motif

Sorted Z-values of bhlhe40 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_32050906 3.13 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr15_+_1534644 3.07 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr5_+_26204561 2.74 ENSDART00000137178
marveld2b
MARVEL domain containing 2b
chr9_+_6587364 2.63 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr7_-_67214972 2.49 ENSDART00000156861
swap70a
switching B cell complex subunit SWAP70a
chr10_+_5268054 2.43 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr17_+_25331576 2.23 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr15_+_59417 2.05 ENSDART00000187260
AXL
AXL receptor tyrosine kinase
chr11_-_44945636 2.05 ENSDART00000157658
orc2
origin recognition complex, subunit 2
chr24_+_7631797 1.98 ENSDART00000187464
cavin1b
caveolae associated protein 1b
chr13_+_7164345 1.95 ENSDART00000022051
gins1
GINS complex subunit 1 (Psf1 homolog)
chr21_+_4540127 1.94 ENSDART00000043431
nup188
nucleoporin 188
chr23_+_35847200 1.94 ENSDART00000129222
rarga
retinoic acid receptor gamma a
chr19_-_5103313 1.88 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr15_+_1148074 1.87 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
mlf1
myeloid leukemia factor 1
chr23_+_32028574 1.70 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr16_+_33143503 1.66 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr23_+_31913292 1.63 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr25_+_10547228 1.61 ENSDART00000067678
zgc:110339
zgc:110339
chr23_-_31913231 1.58 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr12_-_44010532 1.55 ENSDART00000183875
si:ch211-182p11.1
si:ch211-182p11.1
chr6_+_12968101 1.52 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr25_-_19608382 1.48 ENSDART00000022279
ENSDART00000135201
ENSDART00000147223
ENSDART00000190220
ENSDART00000184242
ENSDART00000166824
gtse1
G-2 and S-phase expressed 1
chr1_+_54766943 1.42 ENSDART00000144759
nlrc6
NLR family CARD domain containing 6
chr24_-_42072886 1.42 ENSDART00000171389
CABZ01095370.1

chr15_-_28596507 1.42 ENSDART00000156800
si:ch211-225b7.5
si:ch211-225b7.5
chr15_-_1534232 1.32 ENSDART00000056763
ENSDART00000133943
ift80
intraflagellar transport 80 homolog (Chlamydomonas)
chr16_+_19029297 1.28 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr6_+_7123980 1.28 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
si:ch211-237c6.4
chr24_-_21498802 1.27 ENSDART00000181235
ENSDART00000153695
atp8a2
ATPase phospholipid transporting 8A2
chr11_+_42556395 1.19 ENSDART00000039206
rps23
ribosomal protein S23
chr19_+_19777437 1.10 ENSDART00000170662
hoxa3a
homeobox A3a
chr16_-_7228276 1.09 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr3_+_16922226 1.09 ENSDART00000017646
atp6v0a1a
ATPase H+ transporting V0 subunit a1a
chr23_-_10786400 1.08 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr5_-_66798729 1.07 ENSDART00000113077
FERMT3 (1 of many)
im:7154036
chr24_-_33756003 1.06 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr7_-_41881177 1.06 ENSDART00000174258
ENSDART00000018972
zgc:92818
zgc:92818
chr24_-_6024466 1.04 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr17_-_25331439 1.01 ENSDART00000155422
ENSDART00000082324
zpcx
zona pellucida protein C
chr8_+_23738122 0.96 ENSDART00000062983
rpl10a
ribosomal protein L10a
chr19_+_791538 0.93 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr5_-_4532516 0.92 ENSDART00000192398
cst14b.1
cystatin 14b, tandem duplicate 1
chr1_-_54765262 0.90 ENSDART00000150362
si:ch211-197k17.3
si:ch211-197k17.3
chr7_+_34620418 0.87 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr7_+_22293894 0.84 ENSDART00000056790
tmem256
transmembrane protein 256
chr23_+_9035578 0.82 ENSDART00000140455
ccm2l
cerebral cavernous malformation 2-like
chr12_+_47044707 0.79 ENSDART00000186506
zranb1a
zinc finger, RAN-binding domain containing 1a
chr4_+_17353714 0.78 ENSDART00000136299
nup37
nucleoporin 37
chr4_-_9196291 0.76 ENSDART00000153963
hcfc2
host cell factor C2
chr4_-_5831522 0.75 ENSDART00000008898
foxm1
forkhead box M1
chr23_-_22130778 0.73 ENSDART00000079212
phc2a
polyhomeotic homolog 2a (Drosophila)
chr7_+_1442059 0.73 ENSDART00000173391
si:cabz01090193.1
si:cabz01090193.1
chr8_-_25817106 0.69 ENSDART00000099364
taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_-_44077937 0.67 ENSDART00000110112
lamtor1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr21_-_14251306 0.64 ENSDART00000114715
ENSDART00000181380
man1b1a
mannosidase, alpha, class 1B, member 1a
chr20_-_51386511 0.62 ENSDART00000151429
ENSDART00000066072
rnf8
ring finger protein 8, E3 ubiquitin protein ligase
chr11_-_44163164 0.60 ENSDART00000047126
clcn4
chloride channel, voltage-sensitive 4
chr9_-_27868267 0.60 ENSDART00000079502
dbr1
debranching RNA lariats 1
chr8_-_6943155 0.59 ENSDART00000139545
ENSDART00000033294
wdr13
WD repeat domain 13
chr16_+_25296389 0.59 ENSDART00000114528
tbc1d31
TBC1 domain family, member 31
chr21_+_45816030 0.57 ENSDART00000187056
pitx1
paired-like homeodomain 1
chr4_-_17353972 0.56 ENSDART00000041529
parpbp
PARP1 binding protein
chr21_+_11916788 0.56 ENSDART00000136103
ubap2a
ubiquitin associated protein 2a
chr12_+_17933775 0.56 ENSDART00000186047
ENSDART00000160586
trrap
transformation/transcription domain-associated protein
chr16_+_5251768 0.55 ENSDART00000144558
plecb
plectin b
chr9_+_36946340 0.53 ENSDART00000135281
si:dkey-3d4.3
si:dkey-3d4.3
chr8_+_41229233 0.52 ENSDART00000131135
zgc:152830
zgc:152830
chr9_-_10804796 0.52 ENSDART00000134911
si:ch1073-416j23.1
si:ch1073-416j23.1
chr5_-_22130937 0.50 ENSDART00000138606
las1l
LAS1-like, ribosome biogenesis factor
chr5_+_41476443 0.50 ENSDART00000145228
ENSDART00000137981
ENSDART00000142538
pias2
protein inhibitor of activated STAT, 2
chr12_+_34891529 0.48 ENSDART00000015643
tbcc
tubulin folding cofactor C
chr16_+_7985886 0.48 ENSDART00000126041
ano10a
anoctamin 10a
chr24_+_3307857 0.47 ENSDART00000106527
gyg1b
glycogenin 1b
chr21_+_43178831 0.45 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr19_+_40379771 0.44 ENSDART00000017917
ENSDART00000110699
vps50
vps50
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr7_-_14446512 0.44 ENSDART00000041577
kif7
kinesin family member 7
chr5_+_57210237 0.42 ENSDART00000167660
pja2
praja ring finger ubiquitin ligase 2
chr20_-_29683754 0.40 ENSDART00000130599
ENSDART00000015928
ENSDART00000131219
si:ch211-195d17.2
si:ch211-195d17.2
chr10_-_15644904 0.40 ENSDART00000138389
ENSDART00000101191
ENSDART00000186559
ENSDART00000122170
smc5
structural maintenance of chromosomes 5
chr17_-_14705039 0.40 ENSDART00000154281
ENSDART00000123550
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr10_-_6775271 0.40 ENSDART00000110735
zgc:194281
zgc:194281
chr17_-_2126517 0.40 ENSDART00000013093
zfyve19
zinc finger, FYVE domain containing 19
chr15_+_34939906 0.39 ENSDART00000131182
si:ch73-95l15.3
si:ch73-95l15.3
chr14_-_16810401 0.37 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr20_-_40766387 0.37 ENSDART00000061173
hsdl1
hydroxysteroid dehydrogenase like 1
chr17_+_30843881 0.33 ENSDART00000149600
ENSDART00000148547
tpp1
tripeptidyl peptidase I
chr24_+_33462800 0.33 ENSDART00000166666
ENSDART00000050826
rmc1
regulator of MON1-CCZ1
chr10_-_35108683 0.32 ENSDART00000049633
zgc:110006
zgc:110006
chr12_+_19958845 0.32 ENSDART00000193248
ercc4
excision repair cross-complementation group 4
chr22_+_16759010 0.29 ENSDART00000079638
ENSDART00000113099
tm2d1
TM2 domain containing 1
chr6_+_149405 0.29 ENSDART00000161154
fdx1l
ferredoxin 1-like
chr25_-_1323623 0.26 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calml4b
calmodulin-like 4b
chr9_-_34269066 0.23 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr16_+_26824691 0.20 ENSDART00000135053
zmp:0000001316
zmp:0000001316
chr11_-_236984 0.20 ENSDART00000170778
dusp7
dual specificity phosphatase 7
chr3_-_25420931 0.19 ENSDART00000109601
ENSDART00000182184
bptf
bromodomain PHD finger transcription factor
chr14_+_94946 0.19 ENSDART00000165766
ENSDART00000163778
mcm7
minichromosome maintenance complex component 7
chr2_-_53896300 0.19 ENSDART00000161221
capsla
calcyphosine-like a
chr21_-_5393125 0.18 ENSDART00000146061
psmd5
proteasome 26S subunit, non-ATPase 5
chr20_-_13140309 0.17 ENSDART00000020703
ENSDART00000188594
ints7
integrator complex subunit 7
chr25_-_6223567 0.16 ENSDART00000067512
psma4
proteasome subunit alpha 4
chr22_-_16759151 0.16 ENSDART00000191880
patj
PATJ, crumbs cell polarity complex component
chr10_+_22890791 0.15 ENSDART00000176011
arrb2a
arrestin, beta 2a
chr11_-_2478374 0.15 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr5_-_9540641 0.15 ENSDART00000124384
ENSDART00000160079
gak
cyclin G associated kinase
chr2_+_50967947 0.14 ENSDART00000162288
si:ch211-249o11.5
si:ch211-249o11.5
chr2_-_32486080 0.14 ENSDART00000110821
ttc19
tetratricopeptide repeat domain 19
chr19_-_38830582 0.12 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr19_-_27334394 0.08 ENSDART00000052359
gtf2h4
general transcription factor IIH, polypeptide 4
chr1_+_50639416 0.08 ENSDART00000141977
herc3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr12_-_7280551 0.08 ENSDART00000061633
zgc:171971
zgc:171971
chr15_-_41807371 0.08 ENSDART00000156819
slc25a36b
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36b
chr10_+_22891126 0.07 ENSDART00000057291
arrb2a
arrestin, beta 2a
chr10_-_24724388 0.07 ENSDART00000148582
smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr22_-_16758973 0.07 ENSDART00000145208
patj
PATJ, crumbs cell polarity complex component
chr13_+_12389849 0.07 ENSDART00000086525
atp10d
ATPase phospholipid transporting 10D
chr23_-_2901167 0.06 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr9_-_10805231 0.05 ENSDART00000193913
ENSDART00000078348
si:ch1073-416j23.1
si:ch1073-416j23.1
chr23_+_26079467 0.05 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr3_+_12784460 0.05 ENSDART00000168382
cyp2k8
cytochrome P450, family 2, subfamily K, polypeptide 8
chr20_-_211920 0.05 ENSDART00000104790
znf292b
zinc finger protein 292b
chr4_+_331351 0.04 ENSDART00000132625
tulp4a
tubby like protein 4a
chr19_+_15441022 0.03 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr9_+_54686686 0.02 ENSDART00000066198
rab9a
RAB9A, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of bhlhe40

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 3.5 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 2.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.2 0.7 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.2 3.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 1.1 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.4 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 1.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.3 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 1.5 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.6 GO:0002312 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 2.4 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 0.9 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 1.0 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.9 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.9 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.2 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.0 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 1.7 GO:0005880 nuclear microtubule(GO:0005880)
0.4 1.9 GO:0000811 GINS complex(GO:0000811)
0.2 2.0 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:1990745 EARP complex(GO:1990745)
0.1 1.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 1.7 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.6 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.5 1.9 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 1.7 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 2.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.5 GO:0051117 ATPase binding(GO:0051117)
0.1 1.0 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 2.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.7 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.7 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.5 GO:0070006 manganese ion binding(GO:0030145) metalloaminopeptidase activity(GO:0070006)
0.0 1.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.1 PID AURORA B PATHWAY Aurora B signaling
0.1 1.7 PID AURORA A PATHWAY Aurora A signaling
0.1 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation