ISMARA results: cxxc1a+cxxc1b+mbd1a

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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for cxxc1a+cxxc1b+mbd1a

Z-value: 0.14

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Transcription factors associated with cxxc1a+cxxc1b+mbd1a

Gene Symbol	Gene ID	Gene Info
cxxc1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000025718	CXXC finger protein 1b
mbd1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000101205	methyl-CpG binding domain protein 1a
cxxc1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000101996	CXXC finger protein 1a
cxxc1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000111907	CXXC finger protein 1b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
cxxc1a	dr11_v1_chr8_+_7854130_7854130	-0.43	1.7e-05	Click!
cxxc1b	dr11_v1_chr11_+_25539698_25539698	-0.37	2.5e-04	Click!
mbd1a	dr11_v1_chr8_+_7875110_7875142	-0.37	2.8e-04	Click!

Activity profile of cxxc1a+cxxc1b+mbd1a motif

Sorted Z-values of cxxc1a+cxxc1b+mbd1a motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_38509333 Show fit	0.61	ENSDART00000153482	slc7a9 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr23_-_20345473 Show fit	0.46	ENSDART00000140935	si:rp71-17i16.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:rp71-17i16.6
chr21_+_27448856 Show fit	0.46	ENSDART00000100784	cfbl NCBI UniProt ZFIN ENSEMBL Google Show fit	complement factor b-like
chr11_+_44579865 Show fit	0.43	ENSDART00000173425	nid1b NCBI UniProt ZFIN ENSEMBL Google Show fit	nidogen 1b
chr21_-_28901095 Show fit	0.38	ENSDART00000180820	cxxc5a NCBI UniProt ZFIN ENSEMBL Google Show fit	CXXC finger protein 5a
chr22_-_6988102 Show fit	0.33	ENSDART00000185618	fgfr1bl NCBI UniProt ZFIN ENSEMBL Google Show fit	fibroblast growth factor receptor 1b, like
chr1_-_55166511 Show fit	0.32	ENSDART00000150430 ENSDART00000035725	pane1 NCBI UniProt ZFIN ENSEMBL Google Show fit	proliferation associated nuclear element
chr21_+_29179887 Show fit	0.27	ENSDART00000161941	si:ch211-57b15.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-57b15.1
chr21_-_7995994 Show fit	0.24	ENSDART00000151632	zgc:171965 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:171965
chr18_+_1145571 Show fit	0.23	ENSDART00000135055	rec114 NCBI UniProt ZFIN ENSEMBL Google Show fit	REC114 meiotic recombination protein
chr11_-_438492 Show fit	0.23	ENSDART00000137121 ENSDART00000133784	nuf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	NUF2, NDC80 kinetochore complex component, homolog
chr17_+_3390772 Show fit	0.21	ENSDART00000160073	sntg2 NCBI UniProt ZFIN ENSEMBL Google Show fit	syntrophin, gamma 2
chr11_-_438294 Show fit	0.10	ENSDART00000040812	nuf2 NCBI UniProt ZFIN ENSEMBL Google Show fit	NUF2, NDC80 kinetochore complex component, homolog
chr5_+_23136544 Show fit	0.07	ENSDART00000003428 ENSDART00000109340 ENSDART00000171039 ENSDART00000178821	prps1a NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoribosyl pyrophosphate synthetase 1A
chr3_-_19200571 Show fit	0.06	ENSDART00000131503 ENSDART00000012335	rfx1a NCBI UniProt ZFIN ENSEMBL Google Show fit	regulatory factor X, 1a (influences HLA class II expression)
chr17_+_26803470 Show fit	0.05	ENSDART00000023470	pgrmc2 NCBI UniProt ZFIN ENSEMBL Google Show fit	progesterone receptor membrane component 2
chr1_+_41690402 Show fit	0.04	ENSDART00000177298	fbxo41 NCBI UniProt ZFIN ENSEMBL Google Show fit	F-box protein 41
chr4_-_17278904 Show fit	0.01	ENSDART00000178686 ENSDART00000135730	lrmp NCBI UniProt ZFIN ENSEMBL Google Show fit	lymphoid-restricted membrane protein

Network of associatons between targets according to the STRING database.

First level regulatory network of cxxc1a+cxxc1b+mbd1a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.6	GO:0003333	amino acid transmembrane transport(GO:0003333)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions