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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for dharma

Z-value: 0.78

Motif logo

Transcription factors associated with dharma

Gene Symbol Gene ID Gene Info
ENSDARG00000040955 dharma

Activity profile of dharma motif

Sorted Z-values of dharma motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_45177373 16.77 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr19_+_7567763 14.17 ENSDART00000140411
S100 calcium binding protein A11
chr16_+_23403602 8.30 ENSDART00000159848
S100 calcium binding protein W
chr19_+_5640504 7.31 ENSDART00000179987
alpha(1,3)fucosyltransferase gene 2
chr16_+_23404170 6.87 ENSDART00000170061
S100 calcium binding protein W
chr1_-_45146834 6.36 ENSDART00000144997
si:ch211-239f4.6
chr8_+_36142734 6.20 ENSDART00000159361
ENSDART00000161194
major histocompatibility complex class II integral membrane beta chain gene
chr1_+_40291054 6.13 ENSDART00000136916
von Willebrand factor A domain containing 10, tandem duplicate 1
chr22_-_6404807 5.63 ENSDART00000149399
ENSDART00000063420
si:rp71-1i20.2
chr10_+_32104305 5.33 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr20_-_29482492 4.98 ENSDART00000178308
actin, alpha, cardiac muscle 1a
chr22_-_10486477 4.38 ENSDART00000184366
asporin (LRR class 1)
chr14_-_970853 3.76 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr13_-_39947335 3.65 ENSDART00000056996
secreted frizzled-related protein 5
chr20_-_31067306 3.38 ENSDART00000014163
fibronectin type III domain containing 1
chr19_+_2631565 3.33 ENSDART00000171487
family with sequence similarity 126, member A
chr16_+_29586004 3.22 ENSDART00000149520
MCL1, BCL2 family apoptosis regulator b
chr15_+_17848590 3.14 ENSDART00000168940
zgc:113279
chr4_-_77218637 3.10 ENSDART00000174325
proteasome subunit beta 10
chr18_+_50525109 3.01 ENSDART00000098390
ubiquitin-like 7b (bone marrow stromal cell-derived)
chr3_+_26322596 2.99 ENSDART00000172700
si:ch211-156b7.5
chr8_+_52642869 2.98 ENSDART00000163617
ENSDART00000189997
si:dkey-90l8.3
chr3_+_43825785 2.92 ENSDART00000157619
lipopolysaccharide-induced TNF factor
chr1_+_51479128 2.77 ENSDART00000028018
Meis homeobox 1 a
chr4_+_58667348 2.61 ENSDART00000186596
ENSDART00000180673

chr3_+_43826018 2.54 ENSDART00000166197
ENSDART00000165145
lipopolysaccharide-induced TNF factor
chr2_+_9560740 2.53 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr22_-_26100282 2.50 ENSDART00000166075
platelet-derived growth factor alpha polypeptide a
chr5_-_33035295 2.36 ENSDART00000061153
GLI pathogenesis-related 2
chr25_-_31396479 2.32 ENSDART00000156828
proline rich 33
chr16_-_50952266 2.29 ENSDART00000165408
si:dkeyp-97a10.3
chr22_-_26005894 2.24 ENSDART00000105088
platelet-derived growth factor alpha polypeptide a
chr11_+_1602916 2.23 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
chr8_-_43923788 2.14 ENSDART00000146152
adhesion G protein-coupled receptor D1
chr25_-_37305738 2.14 ENSDART00000154185
si:dkey-234i14.15
chr24_-_24060632 2.08 ENSDART00000090514
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr4_+_69712223 2.01 ENSDART00000163035
ENSDART00000164475
si:dkey-238o14.1
zgc:174944
chr3_+_23742868 1.96 ENSDART00000153512
homeobox B3a
chr18_-_15551360 1.95 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr21_+_15865523 1.94 ENSDART00000155098
glucosaminyl (N-acetyl) transferase 4, core 2, b
chr4_-_76186742 1.90 ENSDART00000163970
si:ch211-106j21.4
chr1_-_47122058 1.89 ENSDART00000159925
ENSDART00000101143
ENSDART00000176803
major histocompatibility complex class I ZEA
chr4_-_34480599 1.85 ENSDART00000159602
ENSDART00000182248
si:dkeyp-51g9.4
si:ch211-64i20.3
chr4_+_966061 1.81 ENSDART00000122535
RNA polymerase II associated protein 3
chr4_+_58661331 1.79 ENSDART00000188763

chr4_-_45043910 1.77 ENSDART00000164068
ENSDART00000123524
ENSDART00000135010
ENSDART00000191778
si:ch211-227e10.6
chr23_+_44644911 1.77 ENSDART00000140799
zgc:85858
chr4_-_10599062 1.73 ENSDART00000048003
tetraspanin 12
chr8_-_25814263 1.70 ENSDART00000143397
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_-_9961488 1.68 ENSDART00000191023
spermatid perinuclear RNA binding protein
chr3_+_23743139 1.66 ENSDART00000187409
homeobox B3a
chr16_+_42830152 1.64 ENSDART00000159730
polymerase (RNA) III (DNA directed) polypeptide G like b
chr4_+_43225728 1.63 ENSDART00000158639
ENSDART00000141339
ENSDART00000137770
ENSDART00000166019
si:ch211-76m11.5
chr4_+_60428812 1.59 ENSDART00000162049
si:dkey-16p6.1
chr7_-_41881177 1.59 ENSDART00000174258
ENSDART00000018972
zgc:92818
chr4_-_56673431 1.57 ENSDART00000161464
ENSDART00000191926
si:ch211-227p7.5
chr4_+_22480169 1.56 ENSDART00000146272
ENSDART00000066904
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr21_+_5080789 1.56 ENSDART00000024199
ATP synthase F1 subunit alpha
chr4_+_71014655 1.56 ENSDART00000170837
si:dkeyp-80d11.14
chr21_-_18086114 1.49 ENSDART00000143987
vav 2 guanine nucleotide exchange factor
chr16_+_42829735 1.47 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr4_-_43862121 1.46 ENSDART00000101961
ENSDART00000183525
si:dkey-261p22.1
chr4_-_75651505 1.45 ENSDART00000115143
si:dkey-71l4.2
chr4_-_56103062 1.45 ENSDART00000165784
ENSDART00000190846
si:dkey-16p6.1
chr10_-_45210184 1.44 ENSDART00000167128
poly (ADP-ribose) glycohydrolase, like
chr14_-_1667154 1.43 ENSDART00000190474

chr3_+_1209006 1.42 ENSDART00000158633
polymerase (DNA-directed), delta interacting protein 3
chr4_-_33073382 1.40 ENSDART00000146414
si:dkeyp-4f2.1
chr4_+_75575252 1.38 ENSDART00000166536
si:ch211-227e10.1
chr19_-_1405363 1.35 ENSDART00000165516
cilia and flagella associated protein 20
chr18_+_907266 1.34 ENSDART00000171729
pyruvate kinase M1/2a
chr22_-_21314821 1.34 ENSDART00000105546
ENSDART00000135388
CDC28 protein kinase regulatory subunit 2
chr24_-_1010467 1.32 ENSDART00000114544
cyclin-dependent kinase 13
chr1_+_27690 1.30 ENSDART00000162928
embryonic ectoderm development
chr4_+_76973771 1.25 ENSDART00000142978
si:dkey-240n22.3
chr5_-_69716501 1.24 ENSDART00000158956
MOB kinase activator 1A
chr4_-_52783184 1.24 ENSDART00000172283
si:dkey-4j21.2
chr4_+_36616118 1.23 ENSDART00000160058
ENSDART00000170506
si:dkey-151g22.1
chr24_-_24271629 1.22 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr4_-_34459615 1.21 ENSDART00000169144
ENSDART00000167022
si:ch211-64i20.3
chr4_-_71214516 1.21 ENSDART00000169997
si:ch211-205a14.7
chr22_+_26290209 1.20 ENSDART00000060898
mitochondrial ribosomal protein S28
chr4_+_57192681 1.19 ENSDART00000190438
si:dkey-16p6.4
chr4_-_47096170 1.17 ENSDART00000161079
si:dkey-26m3.3
chr16_+_14201401 1.17 ENSDART00000113679
death associated protein 3
chr17_-_33414781 1.14 ENSDART00000142203
ENSDART00000034638
coiled-coil domain containing 28A
chr9_+_32073606 1.13 ENSDART00000184170
ENSDART00000180355
ENSDART00000110204
ENSDART00000123278
phosphoinositide kinase, FYVE finger containing
chr20_-_42534504 1.13 ENSDART00000132310
regulatory factor X, 6
chr18_+_26048128 1.12 ENSDART00000164495
ENSDART00000015712
zinc finger protein 710a
chr4_-_39186893 1.11 ENSDART00000150371
ENSDART00000121804
ENSDART00000133901
si:ch211-22k7.9
chr4_+_46812891 1.10 ENSDART00000189655
ENSDART00000162329
si:ch211-215p11.3
chr4_-_71554068 1.09 ENSDART00000167414
si:dkey-27n6.1
chr14_-_25928899 1.09 ENSDART00000143518
GTPase activating protein (SH3 domain) binding protein 1
chr4_-_47095583 1.08 ENSDART00000183595
ENSDART00000183279
ENSDART00000191638
si:dkey-26m3.3
chr21_-_21610857 1.08 ENSDART00000172333
diablo, IAP-binding mitochondrial protein b
chr4_-_71470455 1.08 ENSDART00000172685
si:ch211-76m11.5
chr4_-_38539463 1.07 ENSDART00000158211
si:ch211-209n20.3
chr4_-_34460301 1.07 ENSDART00000192977
si:ch211-64i20.3
chr7_+_13756374 1.04 ENSDART00000180808
RAS-like, family 12
chr4_-_75795899 1.03 ENSDART00000157925
si:dkey-261j11.1
chr4_-_43863085 1.03 ENSDART00000147130
si:dkey-261p22.1
chr3_+_52475058 1.03 ENSDART00000035867
si:ch211-241f5.3
chr16_+_5898878 1.03 ENSDART00000180930
unc-51 like kinase 4
chr4_-_43616331 1.03 ENSDART00000183211
ENSDART00000150240
si:dkey-16p6.4
chr4_+_35227135 0.99 ENSDART00000161023
ENSDART00000182403
si:ch211-276i6.1
chr4_+_67994238 0.98 ENSDART00000160968
si:ch211-133h13.1
chr17_-_30944566 0.97 ENSDART00000192663
Enah/Vasp-like a
chr1_-_44025066 0.95 ENSDART00000148932
si:ch73-109d9.1
chr9_-_14084044 0.92 ENSDART00000141571
fer-1-like family member 6
chr4_-_33763221 0.92 ENSDART00000132613
ENSDART00000191816
ENSDART00000188473
si:ch211-197f20.1
chr23_-_46034609 0.92 ENSDART00000158712
zgc:65873
chr4_+_54862025 0.92 ENSDART00000166721
si:dkey-56m15.9
chr2_-_9744081 0.91 ENSDART00000097732
dishevelled segment polarity protein 3a
chr10_-_11397590 0.91 ENSDART00000064212
SREK1-interacting protein 1
chr4_-_38828508 0.91 ENSDART00000151952
si:dkey-59l11.10
chr4_-_71267777 0.91 ENSDART00000169664
si:dkeyp-51g9.4
chr4_+_45388995 0.91 ENSDART00000150802
si:dkey-16p6.1
chr4_+_47782411 0.88 ENSDART00000161728
si:ch211-196h24.2
chr4_-_67984478 0.88 ENSDART00000160623
si:ch211-223k15.1
chr4_+_6639292 0.87 ENSDART00000158573
si:dkey-112e7.2
chr7_+_66884570 0.86 ENSDART00000082664
SET binding factor 2
chr4_-_34776147 0.85 ENSDART00000167498
si:dkey-146m20.14
chr21_-_2348838 0.85 ENSDART00000160337
si:ch73-299h12.8
chr21_-_20341836 0.84 ENSDART00000176689
retinol binding protein 4, like
chr21_-_20342096 0.83 ENSDART00000065659
retinol binding protein 4, like
chr5_+_13394543 0.83 ENSDART00000051669
ENSDART00000135921
tectonic family member 2
chr4_-_63558838 0.83 ENSDART00000191708
ENSDART00000190740
ENSDART00000186476
si:dkey-16p6.1
chr11_+_27968834 0.81 ENSDART00000147984
alkaline phosphatase, liver/bone/kidney
chr4_+_45389591 0.81 ENSDART00000162530
si:dkey-16p6.1
chr4_-_71471302 0.81 ENSDART00000187687
si:ch211-76m11.5
chr4_+_65487457 0.80 ENSDART00000162017
ENSDART00000193241
si:dkeyp-5g9.1
chr7_+_62004048 0.78 ENSDART00000181818
small integral membrane protein 20
chr12_+_47044707 0.77 ENSDART00000186506
zinc finger, RAN-binding domain containing 1a
chr8_+_30747940 0.76 ENSDART00000098975
purinergic receptor P2X, ligand-gated ion channel, 4b
chr21_-_19330333 0.76 ENSDART00000101462
mitochondrial ribosomal protein S18C
chr7_+_20471315 0.75 ENSDART00000173714
si:dkey-19b23.13
chr4_-_63559311 0.75 ENSDART00000164415
si:dkey-16p6.1
chr4_+_40383229 0.75 ENSDART00000126906
ENSDART00000191198
si:ch211-218h8.1
chr7_+_17953589 0.75 ENSDART00000174778
ENSDART00000113120
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr3_-_14498295 0.74 ENSDART00000172102
ELF1 homolog, elongation factor 1
chr3_+_23092762 0.72 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr13_+_24853578 0.72 ENSDART00000145865
si:dkey-24f15.2
chr18_-_19005919 0.72 ENSDART00000129776
integrator complex subunit 14
chr1_-_44928987 0.65 ENSDART00000134635
si:dkey-9i23.15
chr4_-_70263609 0.65 ENSDART00000163868
si:dkey-3h2.3
chr4_+_51201875 0.65 ENSDART00000189875
ENSDART00000186722

chr5_-_22602979 0.65 ENSDART00000146287
non-POU domain containing, octamer-binding
chr9_-_6502491 0.64 ENSDART00000102672
NCK adaptor protein 2a
chr4_-_38829098 0.64 ENSDART00000151932
si:dkey-59l11.10
chr11_-_2478374 0.63 ENSDART00000173205
si:ch73-267c23.10
chr11_+_17984354 0.63 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr7_+_8456999 0.63 ENSDART00000172880
jacalin 4
chr23_-_26652273 0.59 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr4_+_70341246 0.58 ENSDART00000123408
si:ch211-76m11.3
chr7_+_66884291 0.57 ENSDART00000187499
SET binding factor 2
chr17_+_25426091 0.57 ENSDART00000149241
ENSDART00000121848
serine/arginine repetitive matrix 1
chr5_-_30620625 0.55 ENSDART00000098273
transcobalamin like
chr18_-_29898351 0.55 ENSDART00000138533
ENSDART00000064076
C-x(9)-C motif containing 2
chr7_-_21905851 0.54 ENSDART00000111066
ENSDART00000020288
erythropoietin a
chr3_-_55128258 0.52 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr10_+_11398111 0.50 ENSDART00000064210
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr24_+_37533728 0.49 ENSDART00000061203
ras homolog family member T2
chr15_+_21252532 0.49 ENSDART00000162619
ENSDART00000019636
ENSDART00000144901
ENSDART00000138676
ENSDART00000133821
ENSDART00000146967
ENSDART00000143990
ENSDART00000142070
ENSDART00000132373
upstream transcription factor 1
chr9_+_3170101 0.48 ENSDART00000164878
ENSDART00000160567
ENSDART00000161216
dynein, cytoplasmic 1, intermediate chain 2a
chr11_+_17984167 0.47 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr18_-_17531483 0.46 ENSDART00000061000
Bardet-Biedl syndrome 2
chr13_+_40815012 0.45 ENSDART00000016960
protein kinase, cGMP-dependent, type Ia
chr1_+_292545 0.44 ENSDART00000148261
centromere protein E
chr2_-_32386942 0.43 ENSDART00000131408
upstream binding transcription factor, like
chr7_+_13756215 0.42 ENSDART00000172804
ENSDART00000018801
ENSDART00000115054
RAS-like, family 12
chr11_+_25157374 0.41 ENSDART00000019450
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr21_+_30084823 0.36 ENSDART00000154573
proline-rich basic protein 1
chr9_+_27352298 0.36 ENSDART00000124265
toll-like receptor 20, tandem duplicate 2
chr1_-_49950643 0.35 ENSDART00000138301
sphingomyelin synthase 2
chr14_-_7141550 0.33 ENSDART00000172020
tRNA phosphotransferase 1
chr24_+_35195963 0.32 ENSDART00000158801
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr4_+_60547709 0.32 ENSDART00000158732
si:dkey-211i20.5
chr12_+_27034760 0.32 ENSDART00000181170
ENSDART00000153054
fibrosin
chr15_-_15469079 0.31 ENSDART00000132637
ENSDART00000004220
RAB34, member RAS oncogene family a
chr3_+_16664212 0.29 ENSDART00000013816
zgc:55558
chr14_+_32838110 0.26 ENSDART00000158077
arrestin 3b, retinal (X-arrestin)
chr2_-_5356686 0.23 ENSDART00000124290
mitofusin 1
chr18_+_5850837 0.21 ENSDART00000013150
component of oligomeric golgi complex 8
chr11_+_29770966 0.20 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr2_-_32387441 0.19 ENSDART00000148202
upstream binding transcription factor, like
chr5_+_57442271 0.17 ENSDART00000097395
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr4_-_11053543 0.17 ENSDART00000067262
methyltransferase like 25
chr5_+_4016271 0.16 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
gametogenetin binding protein 2
chr3_-_56030117 0.15 ENSDART00000113030
ENSDART00000157764
centrosomal protein 112
chr6_+_41181869 0.14 ENSDART00000002046
opsin 1 (cone pigments), medium-wave-sensitive, 1
chr23_-_41824460 0.12 ENSDART00000131235
si:ch73-302a13.2
chr12_+_27034594 0.12 ENSDART00000111679
fibrosin
chr4_-_6809323 0.12 ENSDART00000099467
interferon-related developmental regulator 1
chr18_+_7639401 0.11 ENSDART00000092416
RAB, member of RAS oncogene family-like 2
chr18_+_21951551 0.09 ENSDART00000146261
RAN binding protein 10
chr24_+_12133814 0.09 ENSDART00000158562
ENSDART00000159029
ENSDART00000168248
leucine zipper transcription factor-like 1
chr4_-_76105527 0.08 ENSDART00000159108
zgc:110171
chr22_-_26289549 0.07 ENSDART00000043774
SDE2 telomere maintenance homolog (S. pombe)
chr9_-_30502010 0.06 ENSDART00000149483
si:dkey-229b18.3
chr14_-_3944017 0.05 ENSDART00000055817
si:ch73-49o8.1

Network of associatons between targets according to the STRING database.

First level regulatory network of dharma

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.9 4.7 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.8 5.0 GO:0003272 endocardial cushion formation(GO:0003272)
0.5 7.3 GO:0036065 fucosylation(GO:0036065)
0.4 1.3 GO:0065001 specification of axis polarity(GO:0065001)
0.4 1.1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 1.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 3.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.2 1.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 6.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 1.7 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.2 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 3.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.9 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.6 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 3.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 3.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 1.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 2.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.8 GO:0033198 response to ATP(GO:0033198)
0.1 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 3.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 1.0 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.4 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 2.4 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 2.4 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.3 GO:0006096 glycolytic process(GO:0006096)
0.0 0.6 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 3.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 44.8 GO:0035556 intracellular signal transduction(GO:0035556)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0001666 response to hypoxia(GO:0001666)
0.0 1.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.9 GO:0061053 somite development(GO:0061053)
0.0 1.0 GO:0007283 spermatogenesis(GO:0007283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.8 6.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 5.0 GO:0005869 dynactin complex(GO:0005869)
0.2 1.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 0.7 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 1.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 29.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 3.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 7.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.1 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.5 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.3 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.0 29.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.6 7.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.5 4.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 1.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 1.4 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.3 3.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 1.7 GO:0034632 retinol transporter activity(GO:0034632)
0.2 1.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 3.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.3 GO:0030332 cyclin binding(GO:0030332)
0.1 4.4 GO:0005518 collagen binding(GO:0005518)
0.1 3.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 3.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.3 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.0 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 3.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.4 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 15.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.7 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis