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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for dlx3b

Z-value: 0.39

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Transcription factors associated with dlx3b

Gene Symbol Gene ID Gene Info
ENSDARG00000014626 distal-less homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx3bdr11_v1_chr12_+_5708400_57084000.047.1e-01Click!

Activity profile of dlx3b motif

Sorted Z-values of dlx3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_17023392 1.72 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr16_+_5774977 1.67 ENSDART00000134202
cholecystokinin a
chr14_-_36378494 1.46 ENSDART00000058503
glycoprotein M6Aa
chr24_+_22485710 1.42 ENSDART00000146058
si:dkey-40h20.1
chr18_-_1185772 1.31 ENSDART00000143245
neuroplastin b
chr24_-_17029374 1.27 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr6_-_35472923 1.20 ENSDART00000185907
regulator of G protein signaling 8
chr3_-_21280373 1.17 ENSDART00000003939
synaptogyrin 1a
chr18_+_41232719 1.14 ENSDART00000138552
ENSDART00000145863
thyroid hormone receptor interactor 12
chr16_-_12953739 1.06 ENSDART00000103894
calcium channel, voltage-dependent, gamma subunit 8b
chr7_+_30787903 1.03 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr10_-_34871737 0.97 ENSDART00000138755
doublecortin-like kinase 1a
chr1_-_58036509 0.95 ENSDART00000081122
si:ch211-114l13.7
chr21_+_6751760 0.95 ENSDART00000135914
olfactomedin 1b
chr16_-_19890303 0.90 ENSDART00000147161
ENSDART00000079159
histone deacetylase 9b
chr4_-_17629444 0.90 ENSDART00000108814
nuclear receptor interacting protein 2
chr21_+_6751405 0.89 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr19_-_32641725 0.80 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr14_-_34044369 0.78 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr20_-_27225876 0.78 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
chr14_-_30587814 0.76 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr7_-_25895189 0.76 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr4_-_15420452 0.73 ENSDART00000016230
plexin A4
chr15_-_755023 0.73 ENSDART00000155594
zinc finger protein 1011
chr23_+_26946744 0.71 ENSDART00000115141
calcium channel, voltage-dependent, beta 3b
chr21_-_5856050 0.70 ENSDART00000115367

chr14_-_24410673 0.69 ENSDART00000125923
chemokine (C-X-C motif) ligand 14
chr23_-_20051369 0.66 ENSDART00000049836
biglycan b
chr24_-_29963858 0.65 ENSDART00000183442

chr22_-_7129631 0.64 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr10_+_22381802 0.64 ENSDART00000112484
neuroligin 2b
chr18_-_2433011 0.62 ENSDART00000181922
ENSDART00000193276

chr9_-_32730487 0.61 ENSDART00000147795
oligodendrocyte transcription factor 1
chr17_+_44780166 0.61 ENSDART00000156260
transmembrane protein 63C
chr23_+_36130883 0.61 ENSDART00000103132
homeobox C4a
chr16_+_42471455 0.60 ENSDART00000166640
si:ch211-215k15.5
chr21_-_43949208 0.58 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr9_+_11532025 0.58 ENSDART00000109037
cyclin-dependent kinase 5, regulatory subunit 2b (p39)
chr11_+_38280454 0.57 ENSDART00000171496
si:dkey-166c18.1
chr21_-_10488379 0.57 ENSDART00000163878
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr19_+_20793237 0.56 ENSDART00000014774
thioredoxin-like 4A
chr23_+_28582865 0.54 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr21_-_26490186 0.54 ENSDART00000009889
zgc:110540
chr14_+_36220479 0.54 ENSDART00000148319
paired-like homeodomain 2
chr9_-_21976670 0.53 ENSDART00000104322
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr20_+_30490682 0.52 ENSDART00000184871
myelin transcription factor 1-like, a
chr17_-_15546862 0.52 ENSDART00000091021
collagen, type X, alpha 1a
chr2_-_55298075 0.51 ENSDART00000186404
ENSDART00000149062
RAB8A, member RAS oncogene family
chr6_-_6487876 0.51 ENSDART00000137642
centrosomal protein 170Ab
chr25_-_32869794 0.50 ENSDART00000162784
transmembrane protein 266
chr7_-_54679595 0.49 ENSDART00000165320
cyclin D1
chr15_-_9272328 0.48 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr5_+_27525477 0.48 ENSDART00000051491
secreted frizzled-related protein 1a
chr1_+_37752171 0.48 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
si:ch211-15e22.3
chr11_-_6974022 0.48 ENSDART00000172851
si:ch211-43f4.1
chr22_-_3564563 0.47 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr23_-_7799184 0.45 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr10_+_21867307 0.42 ENSDART00000126629
cerebellin 17
chr19_+_20793388 0.41 ENSDART00000142463
thioredoxin-like 4A
chr15_-_42736433 0.41 ENSDART00000154379
si:ch211-181d7.1
chr2_+_2168547 0.41 ENSDART00000029347
HIG1 hypoxia inducible domain family, member 1A
chr11_+_18873113 0.41 ENSDART00000103969
ENSDART00000103968
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr4_-_9891874 0.40 ENSDART00000067193
adrenomedullin 2a
chr11_-_34522249 0.40 ENSDART00000158616
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr2_-_23004286 0.39 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr16_-_13623928 0.38 ENSDART00000164344
si:dkeyp-69b9.6
chr2_-_32826108 0.37 ENSDART00000098834
pre-mRNA processing factor 4Ba
chr7_+_30926289 0.37 ENSDART00000173518
si:dkey-1h4.4
chr7_-_69647988 0.37 ENSDART00000169943

chr11_+_18873619 0.37 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr4_+_14727018 0.36 ENSDART00000124189
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr3_-_28428198 0.35 ENSDART00000151546
RNA binding fox-1 homolog 1
chr20_-_9462433 0.35 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr11_-_19775182 0.35 ENSDART00000037894
nicotinamide phosphoribosyltransferase b
chr24_-_25004553 0.35 ENSDART00000080997
ENSDART00000136860
zinc finger, DHHC-type containing 20b
chr12_+_22580579 0.35 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr1_-_44701313 0.35 ENSDART00000193926
si:dkey-28b4.8
chr16_-_13623659 0.34 ENSDART00000168978
si:dkeyp-69b9.6
chr22_-_24284447 0.34 ENSDART00000149894
si:ch211-117l17.4
chr14_+_23717165 0.34 ENSDART00000006373
Nedd4 family interacting protein 1
chr19_-_42607451 0.33 ENSDART00000004392
FK506 binding protein 9
chr1_+_10318089 0.33 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr18_-_19095141 0.32 ENSDART00000090962
ENSDART00000090922
DENN/MADD domain containing 4A
chr16_-_29194517 0.32 ENSDART00000046114
ENSDART00000148899
myocyte enhancer factor 2d
chr19_+_22062202 0.32 ENSDART00000100181
spalt-like transcription factor 3b
chr2_+_35421285 0.32 ENSDART00000143787
tenascin R (restrictin, janusin)
chr21_+_15824182 0.31 ENSDART00000065779
gonadotropin-releasing hormone 2
chr8_+_28452738 0.31 ENSDART00000062706
transmembrane protein 189
chr8_-_31107537 0.31 ENSDART00000098925
vestigial like 4 like
chr11_-_39105253 0.31 ENSDART00000102827
prolyl 3-hydroxylase 1
chr14_+_25817628 0.31 ENSDART00000047680
glycine receptor, alpha 1
chr16_-_21620947 0.29 ENSDART00000115011
ENSDART00000183125
ENSDART00000188856
ENSDART00000189460
discoidin domain receptor tyrosine kinase 1
chr3_+_17346502 0.28 ENSDART00000187786
ENSDART00000131584
si:ch211-210g13.5
chr3_+_32832538 0.28 ENSDART00000139410
CD2 (cytoplasmic tail) binding protein 2
chr11_+_30244356 0.27 ENSDART00000036050
ENSDART00000150080
retinoschisin 1a
chr15_+_5360407 0.27 ENSDART00000110420
odorant receptor, family A, subfamily 112, member 1
chr5_+_63857055 0.27 ENSDART00000138950
regulator of G protein signaling 3b
chr6_+_9289802 0.26 ENSDART00000188650
kalirin RhoGEF kinase b
chr2_-_28671139 0.26 ENSDART00000165272
ENSDART00000164657
7-dehydrocholesterol reductase
chr17_-_20717845 0.25 ENSDART00000150037
ankyrin 3b
chr7_+_15872357 0.24 ENSDART00000165757
paired box 6b
chr18_-_46258612 0.21 ENSDART00000153930
si:dkey-244a7.1
chr15_-_18115540 0.21 ENSDART00000131639
ENSDART00000047902
archain 1b
chr1_+_23783349 0.20 ENSDART00000007531
slit homolog 2 (Drosophila)
chr4_+_14727212 0.20 ENSDART00000158094
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr16_-_13613475 0.20 ENSDART00000139102
D site albumin promoter binding protein b
chr9_+_11034314 0.19 ENSDART00000032695
acid-sensing (proton-gated) ion channel family member 4a
chr23_-_16682186 0.19 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr1_-_47071979 0.19 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chrM_+_9052 0.18 ENSDART00000093612
ATP synthase 6, mitochondrial
chr18_-_37007294 0.18 ENSDART00000088309
mitogen-activated protein kinase kinase kinase 10
chr21_+_30355767 0.18 ENSDART00000189948

chr25_+_6471401 0.18 ENSDART00000132927
sorting nexin 33
chr4_+_3980247 0.17 ENSDART00000049194
G protein-coupled receptor 37b
chr8_+_18588551 0.17 ENSDART00000177476
ENSDART00000063539
proline rich Gla (G-carboxyglutamic acid) 1
chr11_-_42554290 0.16 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr8_-_5847533 0.16 ENSDART00000192489

chr23_-_18130264 0.16 ENSDART00000016976
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr10_+_32104305 0.16 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr17_+_49500820 0.16 ENSDART00000170306
apoptosis resistant E3 ubiquitin protein ligase 1
chr20_-_35578435 0.16 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr3_-_46811611 0.15 ENSDART00000134092
ELAV like neuron-specific RNA binding protein 3
chr18_+_50461981 0.15 ENSDART00000158761

chr16_-_16120941 0.15 ENSDART00000131227
ankyrin repeat and IBR domain containing 1b
chr21_-_37790727 0.15 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr4_+_57580303 0.14 ENSDART00000166492
ENSDART00000103025
ENSDART00000170786
interleukin 17 receptor A1b
interleukin 17 receptor A2
chr20_+_13783040 0.14 ENSDART00000115329
ENSDART00000152497
lysophosphatidylglycerol acyltransferase 1
chr4_+_22343093 0.14 ENSDART00000023588
guanylate cyclase activator 1A
chr5_-_51619742 0.14 ENSDART00000188537
orthopedia homeobox b
chr8_-_23776399 0.13 ENSDART00000114800
si:ch211-163l21.4
chr12_-_19007834 0.13 ENSDART00000153248
chondroadherin-like b
chr12_+_25432627 0.13 ENSDART00000011662
protein phosphatase, Mg2+/Mn2+ dependent, 1Bb
chr19_+_31904836 0.12 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr13_+_22295905 0.12 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr4_+_41311345 0.12 ENSDART00000151905
si:dkey-16p19.8
chr5_+_56268436 0.11 ENSDART00000021159
LIM homeobox 1b
chr19_-_32914227 0.11 ENSDART00000186115
ENSDART00000124246
metadherin a
chr4_+_12612723 0.11 ENSDART00000133767
LIM domain only 3
chr7_-_12464412 0.11 ENSDART00000178723
ADAMTS-like 3
chr19_-_38830582 0.10 ENSDART00000189966
ENSDART00000183055
adhesion G protein-coupled receptor B2
chr12_-_35386910 0.10 ENSDART00000153453
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr4_+_49322310 0.10 ENSDART00000184154
ENSDART00000167162

chr8_-_24252933 0.10 ENSDART00000057624
zgc:110353
chr3_+_22059066 0.09 ENSDART00000155739
KAT8 regulatory NSL complex subunit 1b
chr2_+_56213694 0.09 ENSDART00000162582
upf1 regulator of nonsense transcripts homolog (yeast)
chr18_-_37007061 0.09 ENSDART00000136432
mitogen-activated protein kinase kinase kinase 10
chr25_+_10410620 0.09 ENSDART00000151886
ets homologous factor
chr20_-_37813863 0.09 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr15_-_33172246 0.09 ENSDART00000158666
neurobeachin b
chr11_-_42418374 0.08 ENSDART00000160704
sarcolemma associated protein a
chr3_-_31079186 0.08 ENSDART00000145636
ENSDART00000140569
elongin B
elongin B
chr2_-_26720854 0.08 ENSDART00000148110
si:dkey-181m9.8
chr8_-_15129573 0.08 ENSDART00000142358
BCAR3, NSP family adaptor protein
chr16_+_31804590 0.08 ENSDART00000167321
wingless-type MMTV integration site family, member 4b
chr20_+_4060839 0.08 ENSDART00000178565
tripartite motif containing 67
chr8_-_43997538 0.07 ENSDART00000186449
RIMS binding protein 2
chr14_-_32631013 0.07 ENSDART00000176815
ATPase phospholipid transporting 11C
chr2_+_35612621 0.07 ENSDART00000143082
si:dkey-4i23.5
chr25_-_18913336 0.07 ENSDART00000171010
parietopsin
chr8_-_39822917 0.07 ENSDART00000067843
zgc:162025
chr14_-_7207961 0.07 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr16_-_20312146 0.06 ENSDART00000134980
si:dkeyp-86h10.3
chr6_-_40713183 0.06 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
chr16_-_21038015 0.05 ENSDART00000059239
sorting nexin 10b
chr11_+_13224281 0.05 ENSDART00000102557
ENSDART00000178706
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr11_-_40147032 0.03 ENSDART00000052918
si:dkey-264d12.4
chr12_-_6818676 0.03 ENSDART00000106391
protocadherin-related 15b
chr20_+_23440632 0.02 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr6_+_60004871 0.02 ENSDART00000179832

chr23_-_19230627 0.02 ENSDART00000007122
guanylate cyclase activator 1B
chr13_+_35339182 0.02 ENSDART00000019323
jagged 1b
chr22_+_21324398 0.02 ENSDART00000168509
SHC (Src homology 2 domain containing) transforming protein 2
chr1_+_57311901 0.01 ENSDART00000149397
mycbp associated protein
chr14_-_33821515 0.01 ENSDART00000173218
vimentin-related 2
chr2_+_32826235 0.01 ENSDART00000143127
si:dkey-154p10.3
chr11_+_33818179 0.00 ENSDART00000109418
speckle-type POZ protein-like b
chr11_+_33312601 0.00 ENSDART00000188024
contactin associated protein-like 5 like
chr10_-_21955231 0.00 ENSDART00000183695

chr20_-_32270866 0.00 ENSDART00000153140
armadillo repeat containing 2
chr5_-_27438812 0.00 ENSDART00000078755
dopamine receptor D7

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0007414 axonal defasciculation(GO:0007414)
0.3 1.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 1.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.5 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 1.1 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.6 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 0.2 GO:0051645 Golgi localization(GO:0051645)
0.1 0.6 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 1.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 1.7 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.4 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767)
0.0 0.6 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.3 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.0 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.7 GO:0003146 heart jogging(GO:0003146)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.2 2.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 1.1 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.0 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.3 GO:0050699 WW domain binding(GO:0050699)
0.1 0.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.6 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 1.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events