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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for drgx_arxb

Z-value: 0.88

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Transcription factors associated with drgx_arxb

Gene Symbol Gene ID Gene Info
drgx
ENSDARG00000069329 dorsal root ganglia homeobox
arxb
ENSDARG00000101523 aristaless related homeobox b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
drgxdr11_v1_chr13_+_30912117_309121170.771.5e-19Click!
arxbdr11_v1_chr21_-_40676224_406762240.462.5e-06Click!

Activity profile of drgx_arxb motif

Sorted Z-values of drgx_arxb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_9669717 21.62 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr25_-_13381854 18.58 ENSDART00000164621
ENSDART00000169129
ndrg4
NDRG family member 4
chr21_-_27881752 16.73 ENSDART00000132583
nrxn2a
neurexin 2a
chr4_-_14315855 14.94 ENSDART00000133325
nell2b
neural EGFL like 2b
chr7_+_26629084 14.36 ENSDART00000101044
ENSDART00000173765
hsbp1a
heat shock factor binding protein 1a
chr24_-_38079261 13.93 ENSDART00000105662
crp1
C-reactive protein 1
chr20_-_20931197 12.90 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr15_+_22435460 12.13 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr18_+_1703984 11.73 ENSDART00000114010
slitrk3a
SLIT and NTRK-like family, member 3a
chr18_-_26785861 10.13 ENSDART00000098361
nmba
neuromedin Ba
chr23_-_12345764 10.05 ENSDART00000133956
phactr3a
phosphatase and actin regulator 3a
chr13_-_29421331 10.05 ENSDART00000150228
chata
choline O-acetyltransferase a
chr17_+_18117029 10.03 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr14_+_19258702 9.76 ENSDART00000187087
ENSDART00000005738
slitrk2
SLIT and NTRK-like family, member 2
chr20_-_20930926 9.68 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr10_-_34772211 9.46 ENSDART00000145450
ENSDART00000134307
dclk1a
doublecortin-like kinase 1a
chr7_-_28148310 9.46 ENSDART00000044208
lmo1
LIM domain only 1
chr24_-_38384432 8.62 ENSDART00000140739
lrrc4bb
leucine rich repeat containing 4Bb
chr10_-_26744131 8.41 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr9_+_34641237 8.36 ENSDART00000133996
shox
short stature homeobox
chr12_+_42436920 7.81 ENSDART00000177303
ebf3a
early B cell factor 3a
chr7_+_21859337 7.11 ENSDART00000159626
si:dkey-85k7.7
si:dkey-85k7.7
chr3_+_46628885 7.03 ENSDART00000006602
pde4a
phosphodiesterase 4A, cAMP-specific
chr9_+_29643036 7.02 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr16_+_22654481 6.96 ENSDART00000179762
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr22_-_32507966 6.95 ENSDART00000104693
pcbp4
poly(rC) binding protein 4
chr18_-_13121983 6.85 ENSDART00000092648
rxylt1
ribitol xylosyltransferase 1
chr6_+_40354424 6.81 ENSDART00000047416
slc4a8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr1_+_53954230 6.80 ENSDART00000037729
ENSDART00000159900
ccsapa
centriole, cilia and spindle-associated protein a
chr7_-_52334840 6.78 ENSDART00000174173
CR938716.1

chr17_-_26926577 6.14 ENSDART00000050202
rcan3
regulator of calcineurin 3
chr6_+_58698475 6.03 ENSDART00000056138
igsf8
immunoglobulin superfamily, member 8
chr21_+_19008168 5.98 ENSDART00000136196
ENSDART00000128381
ENSDART00000176624
nefla
neurofilament, light polypeptide a
chr16_-_27640995 5.94 ENSDART00000019658
nacad
NAC alpha domain containing
chr17_-_14726824 5.80 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr21_-_17482465 5.74 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr8_-_7391721 5.68 ENSDART00000149836
lhfpl4b
LHFPL tetraspan subfamily member 4b
chr22_+_10698549 5.46 ENSDART00000081228
abhd14a
abhydrolase domain containing 14A
chr25_+_18964782 5.37 ENSDART00000017299
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr9_-_27649406 5.29 ENSDART00000181270
ENSDART00000187112
stxbp5l
syntaxin binding protein 5-like
chr12_+_42436328 5.17 ENSDART00000167324
ebf3a
early B cell factor 3a
chr12_-_35386910 5.04 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr6_+_40661703 5.01 ENSDART00000142492
eno1b
enolase 1b, (alpha)
chr1_+_18811679 4.87 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr1_+_25801648 4.84 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr3_-_32337653 4.67 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr9_-_46701326 4.64 ENSDART00000159971
si:ch73-193i22.1
si:ch73-193i22.1
chr14_+_6615564 4.49 ENSDART00000139292
si:dkeyp-44a8.2
si:dkeyp-44a8.2
chr23_-_24682244 4.19 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_+_3610140 4.10 ENSDART00000104977
pick1
protein interacting with prkca 1
chr24_-_7697274 4.10 ENSDART00000186077
syt5b
synaptotagmin Vb
chr12_-_47601845 4.04 ENSDART00000169548
ENSDART00000182889
rgs7b
regulator of G protein signaling 7b
chr12_+_25432627 3.77 ENSDART00000011662
ppm1bb
protein phosphatase, Mg2+/Mn2+ dependent, 1Bb
chr20_+_34320635 3.72 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr10_+_40284003 3.63 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
git2b
G protein-coupled receptor kinase interacting ArfGAP 2b
chr10_+_29698467 3.40 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr15_-_25099679 3.36 ENSDART00000154628
rflnb
refilin B
chr17_-_8268406 3.26 ENSDART00000149873
ENSDART00000064668
ENSDART00000148403
ahi1
Abelson helper integration site 1
chr7_+_29167744 3.14 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr9_+_36314867 3.09 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr6_+_16468776 2.90 ENSDART00000109151
ENSDART00000114667
zgc:161969
zgc:161969
chr15_-_17868870 2.85 ENSDART00000170950
atf5b
activating transcription factor 5b
chr9_-_48407408 2.82 ENSDART00000058248
zgc:172182
zgc:172182
chr24_-_38657683 2.81 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr15_-_17869115 2.79 ENSDART00000112838
atf5b
activating transcription factor 5b
chr4_-_28158335 2.77 ENSDART00000134605
gramd4a
GRAM domain containing 4a
chr2_-_42071558 2.76 ENSDART00000142792
cspp1b
centrosome and spindle pole associated protein 1b
chr17_+_30545895 2.58 ENSDART00000076739
nhsl1a
NHS-like 1a
chr12_+_17504559 2.57 ENSDART00000020628
cyth3a
cytohesin 3a
chr21_-_10446405 2.50 ENSDART00000167948
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr22_+_17433968 2.44 ENSDART00000139523
rabgap1l
RAB GTPase activating protein 1-like
chr24_+_25069609 2.43 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr25_+_5755314 2.38 ENSDART00000172088
ENSDART00000164208
appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr1_-_55873178 2.37 ENSDART00000019936
prkacab
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr1_-_23110740 2.32 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr21_-_43022048 2.29 ENSDART00000138329
dpysl3
dihydropyrimidinase-like 3
chr10_-_33621739 2.27 ENSDART00000142655
ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr10_-_5581487 2.26 ENSDART00000141943
syk
spleen tyrosine kinase
chr19_+_16064439 2.19 ENSDART00000151169
gmeb1
glucocorticoid modulatory element binding protein 1
chr23_-_28025943 2.11 ENSDART00000181146
sp5l
Sp5 transcription factor-like
chr19_+_9174166 2.03 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
si:ch211-81a5.8
chr15_+_23550890 2.01 ENSDART00000009796
ENSDART00000152720
MARK4
si:dkey-31m14.7
chr3_-_26787430 1.99 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr10_-_32920690 1.94 ENSDART00000136245
cux1a
cut-like homeobox 1a
chr15_+_8767650 1.84 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr2_-_30135446 1.77 ENSDART00000141906
trpa1a
transient receptor potential cation channel, subfamily A, member 1a
chr11_+_7432533 1.75 ENSDART00000180977
adgrl2a
adhesion G protein-coupled receptor L2a
chr14_-_17068511 1.71 ENSDART00000163766
phox2bb
paired-like homeobox 2bb
chr17_-_45254585 1.67 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr1_+_38142715 1.65 ENSDART00000079928
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr2_+_38554260 1.64 ENSDART00000171527
cdh24b
cadherin 24, type 2b
chr20_+_11731039 1.63 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr21_-_18262287 1.56 ENSDART00000176716
vav2
vav 2 guanine nucleotide exchange factor
chr17_-_14451718 1.49 ENSDART00000039438
jkamp
jnk1/mapk8 associated membrane protein
chr17_-_39772999 1.48 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr5_+_51079504 1.45 ENSDART00000097466
fam169aa
family with sequence similarity 169, member Aa
chr25_+_33002963 1.42 ENSDART00000187366
CABZ01046980.1

chr15_-_21702317 1.42 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr15_+_25528290 1.41 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr5_-_32489796 1.27 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr13_+_15581270 1.19 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr7_+_71764883 1.15 ENSDART00000166865
myl12.1
myosin, light chain 12, genome duplicate 1
chr21_-_18648861 1.15 ENSDART00000112113
si:dkey-112m2.1
si:dkey-112m2.1
chr1_-_46706639 1.14 ENSDART00000074519
kpna3
karyopherin alpha 3 (importin alpha 4)
chr4_-_16001118 1.14 ENSDART00000041070
ENSDART00000125389
mest
mesoderm specific transcript
chr14_-_22152064 1.13 ENSDART00000115422
nudcd2
NudC domain containing 2
chr18_+_6054816 1.11 ENSDART00000113668
si:ch73-386h18.1
si:ch73-386h18.1
chr7_+_38811800 1.09 ENSDART00000052322
zgc:110699
zgc:110699
chr21_-_37973819 1.07 ENSDART00000133405
ripply1
ripply transcriptional repressor 1
chr23_-_16485190 1.05 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr5_+_61361815 1.01 ENSDART00000009507
gatsl2
GATS protein-like 2
chr18_+_33725576 1.01 ENSDART00000146816
si:dkey-145c18.5
si:dkey-145c18.5
chr23_-_18130264 1.01 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr12_-_20795867 1.00 ENSDART00000152835
ENSDART00000153424
nme2a
NME/NM23 nucleoside diphosphate kinase 2a
chr5_+_48683447 0.96 ENSDART00000008043
adgrv1
adhesion G protein-coupled receptor V1
chr22_+_39007533 0.94 ENSDART00000185958
ENSDART00000129848
fam208aa
family with sequence similarity 208, member Aa
chr12_-_32013125 0.94 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr17_-_14451405 0.93 ENSDART00000146786
jkamp
jnk1/mapk8 associated membrane protein
chr9_-_53537989 0.93 ENSDART00000114022
slitrk5b
SLIT and NTRK-like family, member 5b
chr7_+_47243564 0.90 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr23_+_25135858 0.90 ENSDART00000103986
fam3a
family with sequence similarity 3, member A
chr21_-_44104600 0.82 ENSDART00000044599
oatx
organic anion transporter X
chr8_+_35212233 0.81 ENSDART00000111021
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr6_+_33898293 0.80 ENSDART00000122070
ccdc17
coiled-coil domain containing 17
chr5_-_68074592 0.79 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr11_-_37425407 0.77 ENSDART00000160911
erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_+_49417900 0.73 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr8_+_50953776 0.70 ENSDART00000013870
zgc:56596
zgc:56596
chr13_+_1726953 0.67 ENSDART00000103004
zmp:0000000760
zmp:0000000760
chr11_-_16115804 0.59 ENSDART00000143436
ENSDART00000157928
rpf1
ribosome production factor 1 homolog
chr11_-_3535537 0.58 ENSDART00000165329
ENSDART00000009788
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr11_+_25693395 0.55 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr20_-_28931901 0.52 ENSDART00000153082
ENSDART00000046042
susd6
sushi domain containing 6
chr3_+_29445473 0.52 ENSDART00000020381
grap2a
GRB2-related adaptor protein 2a
chr5_-_18897482 0.49 ENSDART00000010101
ENSDART00000099434
aacs
acetoacetyl-CoA synthetase
chr9_+_48219111 0.47 ENSDART00000111225
ENSDART00000145972
ccdc173
coiled-coil domain containing 173
chr6_+_40832635 0.47 ENSDART00000011931
ruvbl1
RuvB-like AAA ATPase 1
chr16_-_31717851 0.44 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr18_+_3243292 0.44 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr17_-_43863700 0.43 ENSDART00000157530
ahsa1b
AHA1, activator of heat shock protein ATPase homolog 1b
chr7_-_30367650 0.42 ENSDART00000075519
aldh1a2
aldehyde dehydrogenase 1 family, member A2
chr3_-_27601812 0.42 ENSDART00000077734
zgc:66160
zgc:66160
chr15_+_45640906 0.40 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr14_-_46070802 0.40 ENSDART00000038670
elf2a
E74-like factor 2a (ets domain transcription factor)
chr11_-_29816429 0.39 ENSDART00000069132
cybb
cytochrome b-245, beta polypeptide (chronic granulomatous disease)
chr13_+_18507592 0.37 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr6_-_3573716 0.36 ENSDART00000026693
dmbx1b
diencephalon/mesencephalon homeobox 1b
chr21_+_7582036 0.34 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr6_-_10708960 0.31 ENSDART00000157704
si:dkey-34m19.3
si:dkey-34m19.3
chr15_-_5720583 0.29 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr13_-_50002852 0.28 ENSDART00000099439
lyst
lysosomal trafficking regulator
chr5_+_45138934 0.27 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_21825913 0.24 ENSDART00000101986
mrpl30
mitochondrial ribosomal protein L30
chr22_+_17784414 0.24 ENSDART00000188189
ENSDART00000145260
tm6sf2
transmembrane 6 superfamily member 2
chr5_+_34407763 0.19 ENSDART00000188849
ENSDART00000145127
lamc3
laminin, gamma 3
chr14_+_22152060 0.18 ENSDART00000082697
ENSDART00000054982
gabra6a
gamma-aminobutyric acid (GABA) A receptor, alpha 6a
chr2_-_5505094 0.17 ENSDART00000145035
saga
S-antigen; retina and pineal gland (arrestin) a
chr22_-_27113332 0.17 ENSDART00000146951
ENSDART00000178855
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr5_+_42400777 0.16 ENSDART00000183114
BX548073.8

chr20_+_41664350 0.11 ENSDART00000186247
fam184a
family with sequence similarity 184, member A
chr2_-_48153945 0.09 ENSDART00000146553
pfkpb
phosphofructokinase, platelet b
chr22_+_21324398 0.07 ENSDART00000168509
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr16_-_39267185 0.05 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr3_-_31079186 0.04 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr16_-_31718013 0.00 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular

Network of associatons between targets according to the STRING database.

First level regulatory network of drgx_arxb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
1.4 7.0 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
1.3 18.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.3 14.4 GO:0034605 cellular response to heat(GO:0034605)
1.2 4.8 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
1.0 6.8 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.8 2.3 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.7 2.2 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.7 2.8 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.7 4.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.6 5.0 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.6 10.6 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.6 8.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 5.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.4 1.8 GO:0050960 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.4 6.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.4 7.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 1.0 GO:0097264 self proteolysis(GO:0097264)
0.3 3.3 GO:0044458 motile cilium assembly(GO:0044458)
0.3 6.8 GO:0015701 bicarbonate transport(GO:0015701)
0.3 2.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 1.8 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.2 2.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.2 4.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 5.3 GO:0050708 regulation of protein secretion(GO:0050708)
0.2 16.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 8.4 GO:0030282 bone mineralization(GO:0030282)
0.2 2.4 GO:0007398 ectoderm development(GO:0007398)
0.2 3.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 2.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 5.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 5.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 2.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 2.4 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.3 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.5 GO:0000492 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.1 2.1 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 3.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 9.8 GO:0021782 glial cell development(GO:0021782)
0.1 0.8 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.7 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 1.0 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 2.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 5.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 3.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.3 GO:0021767 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 4.6 GO:0006612 protein targeting to membrane(GO:0006612)
0.1 4.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 1.1 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 2.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 10.0 GO:0007409 axonogenesis(GO:0007409)
0.0 14.5 GO:0045893 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.6 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 1.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 11.6 GO:0022008 neurogenesis(GO:0022008)
0.0 0.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0098842 postsynaptic early endosome(GO:0098842)
1.0 5.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.6 5.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 4.1 GO:0031045 dense core granule(GO:0031045)
0.2 1.0 GO:0060171 stereocilium membrane(GO:0060171)
0.2 7.0 GO:0035869 ciliary transition zone(GO:0035869)
0.2 1.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 10.7 GO:0030426 growth cone(GO:0030426)
0.1 3.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 4.7 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 2.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 1.9 GO:0043195 terminal bouton(GO:0043195)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818)
0.1 5.3 GO:0031201 SNARE complex(GO:0031201)
0.1 5.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 6.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 7.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 26.4 GO:0043005 neuron projection(GO:0043005)
0.0 43.4 GO:0005829 cytosol(GO:0005829)
0.0 1.6 GO:0016342 catenin complex(GO:0016342)
0.0 2.3 GO:0000922 spindle pole(GO:0000922)
0.0 10.6 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 7.4 GO:0000785 chromatin(GO:0000785)
0.0 1.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 8.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.1 GO:0031705 bombesin receptor binding(GO:0031705)
1.1 19.0 GO:0005080 protein kinase C binding(GO:0005080)
1.0 6.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.9 4.7 GO:0016531 copper chaperone activity(GO:0016531)
0.8 10.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.6 5.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 5.4 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.6 2.2 GO:0031005 filamin binding(GO:0031005)
0.5 6.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.5 2.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.5 4.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 8.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 5.3 GO:0045159 myosin II binding(GO:0045159)
0.3 7.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 4.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 10.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 4.6 GO:0015026 coreceptor activity(GO:0015026)
0.2 2.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.5 GO:0030552 cAMP binding(GO:0030552)
0.1 6.0 GO:0008374 O-acyltransferase activity(GO:0008374)
0.1 5.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 3.8 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 13.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 4.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965) cyclase regulator activity(GO:0010851)
0.1 1.1 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 4.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 2.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0016918 retinal binding(GO:0016918)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 6.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 2.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 5.8 GO:0016874 ligase activity(GO:0016874)
0.0 1.0 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 3.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 12.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 5.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.6 GO:0045296 cadherin binding(GO:0045296)
0.0 5.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 4.9 GO:0008017 microtubule binding(GO:0008017)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.0 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 4.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 2.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 2.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 7.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 2.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 4.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 6.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes