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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for e4f1+si:dkeyp-79b7.12

Z-value: 0.78

Motif logo

Transcription factors associated with e4f1+si:dkeyp-79b7.12

Gene Symbol Gene ID Gene Info
ENSDARG00000038243 E4F transcription factor 1
ENSDARG00000105305 si_dkeyp-79b7.12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e4f1dr11_v1_chr3_-_18737126_187371260.831.6e-24Click!
si:dkeyp-79b7.12dr11_v1_chr22_+_2207502_22075020.534.4e-08Click!

Activity profile of e4f1+si:dkeyp-79b7.12 motif

Sorted Z-values of e4f1+si:dkeyp-79b7.12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_51606552 7.60 ENSDART00000130828
cannabinoid receptor interacting protein 1a
chr2_-_42415902 7.41 ENSDART00000142489
solute carrier organic anion transporter family member 5A1b
chr24_-_7632187 7.18 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr23_-_35694171 7.14 ENSDART00000077539
tubulin, alpha 1c
chr15_-_163586 6.90 ENSDART00000163597
septin-4
chr4_+_9669717 6.26 ENSDART00000004604
si:dkey-153k10.9
chr20_+_29743904 6.17 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr23_-_35694461 5.46 ENSDART00000185884
tubulin, alpha 1c
chr22_-_29922872 5.44 ENSDART00000020249
dual specificity phosphatase 5
chr23_-_29668286 5.03 ENSDART00000129248
calsyntenin 1
chr7_+_29133321 4.86 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr9_+_21722733 4.68 ENSDART00000102021
SRY (sex determining region Y)-box 1a
chr16_+_32995882 4.57 ENSDART00000170157
protease, serine, 35
chr16_-_45069882 4.29 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr20_-_44576949 4.12 ENSDART00000148639
UBX domain protein 2A
chr20_-_37629084 3.77 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr7_+_22616212 3.76 ENSDART00000052844
claudin 7a
chr9_-_42418470 3.69 ENSDART00000144353
calcitonin receptor-like a
chr10_+_6496185 3.68 ENSDART00000164770
receptor accessory protein 5
chr11_+_4026229 3.65 ENSDART00000041417
calcium/calmodulin-dependent protein kinase Ib
chr18_+_6857071 3.58 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr20_+_25911342 3.55 ENSDART00000146004
tau tubulin kinase 2b
chr23_-_30764319 3.42 ENSDART00000075918
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr3_+_20156956 3.16 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr16_+_25137483 3.05 ENSDART00000155666
zinc finger protein 576, tandem duplicate 1
chr2_+_9821757 2.96 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr11_+_40649412 2.95 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr6_-_48311 2.93 ENSDART00000131010
zgc:114175
chr10_+_44903676 2.91 ENSDART00000158553
zgc:114173
chr10_-_41906609 2.86 ENSDART00000102530
lysine (K)-specific demethylase 2Bb
chr17_+_8184649 2.83 ENSDART00000091818
tubby like protein 4b
chr16_-_32649929 2.81 ENSDART00000136161
failed axon connections homolog b
chr20_+_19512727 2.77 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr15_-_1844048 2.72 ENSDART00000102410
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_-_11655031 2.71 ENSDART00000044314
integrin, alpha V
chr19_-_32888758 2.68 ENSDART00000052080
lysosomal protein transmembrane 4 beta
chr13_+_32446169 2.67 ENSDART00000143325
5'-nucleotidase, cytosolic IB a
chr9_-_54840124 2.67 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr3_+_18555899 2.64 ENSDART00000163036
ENSDART00000158791
chromobox homolog 4 (Pc class homolog, Drosophila)
chr3_-_21137362 2.54 ENSDART00000104051
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr8_+_40628926 2.47 ENSDART00000163598
dual specificity phosphatase 2
chr16_+_24681177 2.41 ENSDART00000058956
ENSDART00000189335
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr3_-_11624694 2.23 ENSDART00000127157
hepatic leukemia factor a
chr22_+_33362552 2.23 ENSDART00000101580
nicolin 1
chr6_+_52350443 2.18 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr19_+_46222428 2.18 ENSDART00000183984
vacuolar protein sorting 28 (yeast)
chr14_+_31493119 2.11 ENSDART00000006463
PHD finger protein 6
chr13_-_38792061 2.05 ENSDART00000162858
LMBR1 domain containing 1
chr3_+_26019426 2.02 ENSDART00000135389
ENSDART00000182411
FAD-dependent oxidoreductase domain containing 2
chr6_+_52212574 1.94 ENSDART00000025940
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr12_+_33320504 1.93 ENSDART00000021491
casein kinase 1, delta b
chr15_+_5116179 1.91 ENSDART00000101937
phosphoglucomutase 2-like 1
chr8_+_23147218 1.90 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr8_-_9118958 1.89 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr16_+_21242491 1.88 ENSDART00000145886
oxysterol binding protein-like 3b
chr15_-_1843831 1.85 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr23_-_5759242 1.84 ENSDART00000055087
pleckstrin homology-like domain, family A, member 3
chr8_-_24113575 1.84 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr21_-_43606502 1.71 ENSDART00000151030
si:ch73-362m14.4
chr2_+_30103131 1.70 ENSDART00000185119
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr5_+_24128908 1.69 ENSDART00000029719
si:ch211-114c12.2
chr12_+_33320884 1.68 ENSDART00000188988
casein kinase 1, delta b
chr20_+_16639848 1.67 ENSDART00000063944
ENSDART00000152359
transmembrane protein 30Ab
chr25_-_23052707 1.61 ENSDART00000024633
dual specificity phosphatase 8a
chr2_+_9560740 1.60 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr24_-_12689571 1.60 ENSDART00000015517
programmed cell death 6
chr5_+_26921033 1.60 ENSDART00000051483
TM2 domain containing 2
chr18_-_7539469 1.58 ENSDART00000101296
si:dkey-30c15.2
chr9_-_13963078 1.56 ENSDART00000193398
ENSDART00000061156
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr19_-_20106486 1.55 ENSDART00000043924
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr2_-_10386738 1.55 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr14_+_30413758 1.45 ENSDART00000092953
CCR4-NOT transcription complex, subunit 7
chr21_-_45613564 1.42 ENSDART00000160324

chr20_+_36812368 1.41 ENSDART00000062931
ABRA C-terminal like
chr13_+_17702853 1.39 ENSDART00000145438
si:dkey-27m7.4
chr14_-_6225336 1.37 ENSDART00000111681
highly divergent homeobox
chr2_-_19354622 1.35 ENSDART00000168627
zinc finger, FYVE domain containing 9a
chr4_+_1722899 1.35 ENSDART00000021139
FGFR1 oncogene partner 2
chr18_+_38775277 1.33 ENSDART00000186129
family with sequence similarity 214, member A
chr25_-_13659249 1.33 ENSDART00000045488
casein kinase 2, alpha prime polypeptide b
chr11_-_17782930 1.32 ENSDART00000080770
TATA element modulatory factor 1
chr6_+_7249531 1.26 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
DAZ interacting zinc finger protein 1
chr3_+_36713477 1.23 ENSDART00000181105
ENSDART00000161897
ENSDART00000189952
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr13_+_23843712 1.17 ENSDART00000057611
opioid receptor, mu 1
chr13_+_35856463 1.14 ENSDART00000171056
ENSDART00000017202
potassium channel, subfamily K, member 1b
chr14_+_31493306 1.13 ENSDART00000138341
PHD finger protein 6
chr14_+_30413312 1.12 ENSDART00000186864
CCR4-NOT transcription complex, subunit 7
chr6_+_58832155 1.11 ENSDART00000144842
dynactin 2 (p50)
chr16_-_4770233 1.10 ENSDART00000193228
replication protein A2
chr22_-_10541712 1.10 ENSDART00000013933
si:dkey-42i9.4
chr4_+_40953320 1.08 ENSDART00000151912
zinc finger protein 1136
chr10_-_26744131 1.07 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fibroblast growth factor 13b
chr23_-_17509656 1.07 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr3_-_15487111 1.03 ENSDART00000011320
nuclear factor of activated T cells 2 interacting protein
chr23_-_3409140 1.03 ENSDART00000002309
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr15_-_8309207 1.01 ENSDART00000143880
ENSDART00000061351
tumor necrosis factor receptor superfamily, member 19
chr5_+_6955900 1.01 ENSDART00000099417

chr5_+_57715614 0.98 ENSDART00000037181
ubiquitin-fold modifier conjugating enzyme 1
chr20_-_51727860 0.97 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr25_-_34632050 0.96 ENSDART00000170671
multiple EGF-like-domains 8
chr15_-_5892650 0.95 ENSDART00000154812
bromodomain and WD repeat domain containing 1
chr18_+_25752592 0.95 ENSDART00000111767
si:ch211-39k3.2
chr1_-_55166511 0.94 ENSDART00000150430
ENSDART00000035725
proliferation associated nuclear element
chr7_-_12909352 0.90 ENSDART00000172901
SH3-domain GRB2-like 3a
chr2_+_6999369 0.90 ENSDART00000050597
xenotropic and polytropic retrovirus receptor 1b
chr25_-_36044583 0.90 ENSDART00000073432
retinoblastoma-like 2 (p130)
chr8_+_23147609 0.87 ENSDART00000180284
GID complex subunit 8 homolog a (S. cerevisiae)
chr24_-_37326236 0.86 ENSDART00000003789
3-phosphoinositide dependent protein kinase 1b
chr9_+_219124 0.85 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr24_-_35534273 0.83 ENSDART00000026578
ubiquitin-conjugating enzyme E2 variant 2
chr6_+_12462079 0.83 ENSDART00000192029
ENSDART00000065385
nuclear receptor subfamily 4, group A, member 2b
chr19_+_31904836 0.82 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr25_+_34845115 0.82 ENSDART00000061996
transmembrane protein 231
chr19_+_20163826 0.80 ENSDART00000090942
ENSDART00000134650
coiled-coil domain containing 126
chr23_+_17509794 0.74 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr8_+_49433663 0.74 ENSDART00000140481
ENSDART00000180714
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr18_+_29402623 0.73 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr3_+_40284598 0.67 ENSDART00000009411
BUD31 homolog (S. cerevisiae)
chr7_-_26518086 0.66 ENSDART00000058913
eukaryotic translation initiation factor 4A1A
chr16_-_4769877 0.65 ENSDART00000149421
ENSDART00000054078
replication protein A2
chr23_-_3408777 0.65 ENSDART00000193245
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr9_-_27749936 0.64 ENSDART00000064156
TBCC domain containing 1
chr15_-_34658057 0.63 ENSDART00000110964
BCL2 associated athanogene 6
chr4_-_149334 0.63 ENSDART00000163280
TANK-binding kinase 1
chr13_+_17702522 0.61 ENSDART00000057913
si:dkey-27m7.4
chr1_-_44037843 0.59 ENSDART00000160276
si:ch73-109d9.3
chr17_-_8673567 0.55 ENSDART00000192714
ENSDART00000012546
C-terminal binding protein 2a
chr9_-_52386733 0.55 ENSDART00000171721
death associated protein 1b
chr13_+_18507592 0.53 ENSDART00000142622
si:ch211-198a12.6
chr4_+_73051901 0.53 ENSDART00000174219
zgc:152938
chr20_+_9211237 0.52 ENSDART00000139527
si:ch211-59d15.4
chr23_+_31405497 0.52 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr17_-_9995667 0.45 ENSDART00000148463
sorting nexin 6
chr20_-_18915376 0.42 ENSDART00000063725
XK, Kell blood group complex subunit-related family, member 6b
chr9_+_33334501 0.40 ENSDART00000006867
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr20_-_32446406 0.37 ENSDART00000026635
nuclear receptor subfamily 2, group E, member 1
chr21_-_43474012 0.36 ENSDART00000065104
transmembrane protein 185
chr25_+_18711804 0.33 ENSDART00000011149
family with sequence similarity 185, member A
chr17_+_8754020 0.33 ENSDART00000105322
erythroid differentiation regulatory factor 1
chr25_+_34845469 0.29 ENSDART00000145416
transmembrane protein 231
chr10_-_11353101 0.29 ENSDART00000092110
lin-54 DREAM MuvB core complex component
chr10_+_35554219 0.26 ENSDART00000077373
zinc finger, DHHC-type containing 20a
chr3_+_61221194 0.23 ENSDART00000110030
lemur tyrosine kinase 2
chr1_-_51062405 0.19 ENSDART00000006381
presenilin 2
chr7_+_66634167 0.18 ENSDART00000027616
eukaryotic translation initiation factor 4, gamma 2a
chr10_-_9089545 0.17 ENSDART00000080781
ADP-ribosylation factor-like 15b
chr23_-_41824460 0.15 ENSDART00000131235
si:ch73-302a13.2
chr4_+_77076645 0.13 ENSDART00000174346

chr8_+_44714336 0.12 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr18_-_19103929 0.12 ENSDART00000188370
ENSDART00000177621
DENN/MADD domain containing 4A
chr15_-_23721618 0.11 ENSDART00000109318
zinc finger CCCH-type containing 4
chr8_-_19266325 0.10 ENSDART00000036148
ENSDART00000137994
zgc:77486
chr6_+_52212927 0.10 ENSDART00000143458
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a
chr3_-_18373604 0.10 ENSDART00000148132
sperm associated antigen 9a
chr8_-_410199 0.10 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
tripartite motif containing 36
chr9_-_6501924 0.08 ENSDART00000168143
NCK adaptor protein 2a
chr5_+_58455488 0.08 ENSDART00000038602
ENSDART00000127958
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr23_+_44633858 0.07 ENSDART00000180728
si:ch73-265d7.2
chr4_-_26035770 0.07 ENSDART00000124514
ubiquitin specific peptidase 44
chr4_-_12930086 0.07 ENSDART00000013604
LEM domain containing 3
chr13_-_36439061 0.06 ENSDART00000084867
ddb1 and cul4 associated factor 5
chr17_+_13007307 0.05 ENSDART00000064554
protein phosphatase 2, regulatory subunit B'', gamma
chr17_+_8754426 0.04 ENSDART00000185519
erythroid differentiation regulatory factor 1
chr12_-_34852342 0.02 ENSDART00000152968
si:dkey-21c1.1
chr23_-_20126257 0.01 ENSDART00000005021
transketolase b

Network of associatons between targets according to the STRING database.

First level regulatory network of e4f1+si:dkeyp-79b7.12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.9 2.7 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.8 7.6 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.7 2.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.7 9.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.6 2.5 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.5 1.5 GO:0061355 Wnt protein secretion(GO:0061355)
0.5 7.2 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.5 2.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.4 1.7 GO:0021742 abducens nucleus development(GO:0021742)
0.4 1.2 GO:0042908 xenobiotic transport(GO:0042908)
0.4 1.8 GO:0031627 telomeric loop formation(GO:0031627)
0.3 1.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 1.4 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.2 4.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 2.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 2.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 2.9 GO:0009303 rRNA transcription(GO:0009303)
0.2 1.0 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.2 1.0 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.6 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.2 2.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 3.7 GO:0048844 artery morphogenesis(GO:0048844)
0.1 1.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 3.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.9 GO:0072501 microglia differentiation(GO:0014004) cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 4.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 1.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.1 GO:0030719 P granule organization(GO:0030719)
0.1 1.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 3.6 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 4.7 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 3.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 4.3 GO:0006096 glycolytic process(GO:0006096)
0.1 2.1 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.8 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 10.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.9 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.8 GO:0006301 postreplication repair(GO:0006301)
0.0 0.9 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 2.1 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 12.6 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0034205 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 3.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.7 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.1 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 1.9 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.1 GO:0032880 regulation of protein localization(GO:0032880)
0.0 1.6 GO:0021782 glial cell development(GO:0021782)
0.0 1.6 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 1.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 2.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 8.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 2.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.7 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818)
0.1 3.1 GO:0035869 ciliary transition zone(GO:0035869)
0.1 3.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 4.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0005869 dynactin complex(GO:0005869)
0.1 2.3 GO:0043204 perikaryon(GO:0043204)
0.0 1.8 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 13.7 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 5.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.7 GO:0030658 transport vesicle membrane(GO:0030658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
1.1 4.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.9 4.5 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.7 9.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.6 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 7.2 GO:0051117 ATPase binding(GO:0051117)
0.5 3.2 GO:0005035 death receptor activity(GO:0005035)
0.4 1.2 GO:0038046 enkephalin receptor activity(GO:0038046)
0.4 3.0 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 1.0 GO:0071568 UFM1 transferase activity(GO:0071568)
0.3 2.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 1.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 0.9 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.3 2.1 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 12.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 6.2 GO:0030165 PDZ domain binding(GO:0030165)
0.2 1.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 1.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.6 GO:0070513 death domain binding(GO:0070513)
0.1 2.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 3.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 3.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 2.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.1 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 3.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 7.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 5.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 2.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 12.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 2.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 4.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 2.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4