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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for elf3

Z-value: 0.82

Motif logo

Transcription factors associated with elf3

Gene Symbol Gene ID Gene Info
ENSDARG00000077982 E74-like factor 3 (ets domain transcription factor, epithelial-specific )

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf3dr11_v1_chr22_+_661711_6617110.232.4e-02Click!

Activity profile of elf3 motif

Sorted Z-values of elf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_24245682 4.81 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr7_-_38633867 4.61 ENSDART00000137424
C1q and TNF related 4
chr17_-_6730247 4.23 ENSDART00000031091
visinin-like 1b
chr14_-_32016615 3.57 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr19_+_30662529 3.52 ENSDART00000175662
family with sequence similarity 49, member A-like
chr6_-_19351495 3.45 ENSDART00000164287
growth factor receptor-bound protein 2a
chr13_+_30054996 3.34 ENSDART00000110061
ENSDART00000186045
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr13_+_27316632 3.28 ENSDART00000016121
eukaryotic translation elongation factor 1 alpha 1a
chr13_+_27316934 3.24 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr24_-_24146875 3.18 ENSDART00000173052
MAP7 domain containing 2b
chr16_-_25393699 3.16 ENSDART00000149445
par-6 family cell polarity regulator gamma a
chr1_-_625875 3.12 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr5_+_32141790 3.00 ENSDART00000041504
tescalcin b
chr4_-_27301356 2.92 ENSDART00000100444
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr12_+_30705769 2.90 ENSDART00000186448
ENSDART00000066259
potassium channel, subfamily K, member 1a
chr10_+_3507861 2.87 ENSDART00000092684
rabphilin 3A homolog (mouse), a
chr10_+_21576909 2.87 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr22_-_16377960 2.84 ENSDART00000168170
tetratricopeptide repeat domain 39C
chr20_-_22798794 2.76 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr17_+_19626479 2.76 ENSDART00000044993
ENSDART00000131863
regulator of G protein signaling 7a
chr25_+_34749812 2.75 ENSDART00000185712
WW domain containing E3 ubiquitin protein ligase 2
chr1_+_31112436 2.65 ENSDART00000075340
eukaryotic translation elongation factor 1 alpha 1b
chr16_+_14033121 2.61 ENSDART00000135844
RUN and SH3 domain containing 1
chr23_+_44745317 2.60 ENSDART00000165654
ATPase Na+/K+ transporting subunit beta 2a
chr4_-_12978925 2.59 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr22_+_2598998 2.57 ENSDART00000176665

chr4_-_64284924 2.56 ENSDART00000166733

chr13_+_31070181 2.55 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
chr3_-_50277959 2.55 ENSDART00000082773
ENSDART00000139524
ADP-ribosylation factor-like 16
chr13_+_30055171 2.38 ENSDART00000143581
ENSDART00000132027
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_46718353 2.34 ENSDART00000074514
SPRY domain containing 7a
chr4_-_4261673 2.32 ENSDART00000150694
CD9 molecule b
chr5_+_52067723 2.24 ENSDART00000166902
SET binding protein 1
chr10_+_32561317 2.24 ENSDART00000109029
microtubule-associated protein 6a
chr13_-_21701323 2.22 ENSDART00000164112
si:dkey-191g9.7
chr2_+_31838442 2.21 ENSDART00000066789
STARD3 N-terminal like
chr12_-_43435254 2.21 ENSDART00000182723
protein tyrosine phosphatase, receptor type, E, a
chr20_-_18382708 2.20 ENSDART00000170864
ENSDART00000166762
ENSDART00000191333
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr12_-_16084835 2.16 ENSDART00000090881
potassium voltage-gated channel, subfamily J, member 19b
chr3_+_46479705 2.15 ENSDART00000181564
tyrosine kinase 2
chr8_+_50742975 2.06 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
chr1_+_10318089 2.06 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr20_+_38285671 2.05 ENSDART00000061432
chemokine (C-C motif) ligand 38, duplicate 4
chr5_+_42467867 2.04 ENSDART00000172028
Pim proto-oncogene, serine/threonine kinase, related 58
chr1_-_18848955 2.03 ENSDART00000109294
ENSDART00000146410
zgc:195282
chr6_-_17849786 2.00 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr15_+_15415623 1.99 ENSDART00000127436
zgc:92630
chr1_+_1904419 1.95 ENSDART00000142874
si:ch211-132g1.4
chr7_+_48460239 1.95 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr1_+_51386649 1.93 ENSDART00000152289
autophagy related 4D, cysteine peptidase a
chr16_+_1802307 1.88 ENSDART00000180026
glutamate ionotropic receptor kainate type subunit 2
chr10_-_41450367 1.86 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr15_-_2010926 1.86 ENSDART00000155688
dedicator of cytokinesis 10
chr16_-_55028740 1.82 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr11_-_18601955 1.80 ENSDART00000180565
zinc finger, MYND-type containing 8
chr14_-_34276574 1.79 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr8_+_8712446 1.79 ENSDART00000158674
ELK1, member of ETS oncogene family
chr2_+_25929619 1.78 ENSDART00000137746
solute carrier family 7, member 14a
chr7_-_7676186 1.76 ENSDART00000091105
microfibril associated protein 3 like
chr13_+_33304187 1.76 ENSDART00000075826
ENSDART00000145295
doublecortin domain containing 2B
chr9_+_6079528 1.75 ENSDART00000142167
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr21_-_2217685 1.74 ENSDART00000159315
si:dkey-50i6.5
chr6_-_19340889 1.73 ENSDART00000181407
MIF4G domain containing a
chr17_-_44440832 1.72 ENSDART00000148786
exocyst complex component 5
chr16_+_34528409 1.71 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr6_+_32393057 1.70 ENSDART00000190765
dedicator of cytokinesis 7
chr14_+_20911310 1.70 ENSDART00000160318
lysozyme g-like 2
chr15_-_26570948 1.70 ENSDART00000156621
WD repeat domain 81
chr22_-_20342260 1.67 ENSDART00000161610
ENSDART00000165667
transcription factor 3b
chr1_+_40237276 1.66 ENSDART00000037553
fatty acid amide hydrolase 2a
chr20_-_13625588 1.66 ENSDART00000078893
synaptotagmin-like 3
chr16_-_16590780 1.66 ENSDART00000059841
si:ch211-257p13.3
chr12_+_30706158 1.62 ENSDART00000133869
potassium channel, subfamily K, member 1a
chr9_-_25425381 1.62 ENSDART00000129522
activin A receptor type 2Aa
chr11_-_29816429 1.60 ENSDART00000069132
cytochrome b-245, beta polypeptide (chronic granulomatous disease)
chr16_+_46807214 1.60 ENSDART00000185524

chr3_-_30625219 1.60 ENSDART00000151698
synaptotagmin III
chr8_-_11202378 1.59 ENSDART00000147817
ENSDART00000174039
family with sequence similarity 208, member B
chr14_+_28438947 1.58 ENSDART00000006489
acyl-CoA synthetase long chain family member 4a
chr15_+_16525126 1.58 ENSDART00000193455
polypeptide N-acetylgalactosaminyltransferase 17
chr2_-_59327299 1.54 ENSDART00000133734
finTRIM family, member 36
chr2_+_27652386 1.54 ENSDART00000188261
transmembrane protein 68
chr22_-_21176269 1.54 ENSDART00000112839
required for excision 1-B domain containing
chr23_+_42304602 1.53 ENSDART00000166004
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr24_-_9960290 1.52 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr4_+_2655358 1.52 ENSDART00000007638
B cell receptor associated protein 29
chr1_+_55293424 1.51 ENSDART00000152464
zgc:172106
chr22_-_16377666 1.50 ENSDART00000161878
tetratricopeptide repeat domain 39C
chr13_+_30696286 1.49 ENSDART00000192411
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr18_-_48508585 1.49 ENSDART00000133364
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr5_-_35137365 1.48 ENSDART00000141218
FCH domain only 2
chr4_-_23963838 1.47 ENSDART00000133433
ENSDART00000132615
ENSDART00000135942
ENSDART00000139439
cugbp, Elav-like family member 2
chr3_-_24205339 1.47 ENSDART00000157135
si:dkey-110g7.8
chr17_-_51223788 1.47 ENSDART00000149864
presenilin 1
chr5_-_37959874 1.47 ENSDART00000031719
myelin protein zero-like 2b
chr6_-_41079209 1.46 ENSDART00000151592
RAB44, member RAS oncogene family
chr19_-_20430892 1.44 ENSDART00000111409
TBC1 domain family, member 5
chr4_+_26629368 1.43 ENSDART00000183575
IQ motif and Sec7 domain 3a
chr3_-_37571601 1.43 ENSDART00000016407
ADP-ribosylation factor 2a
chr2_+_36721357 1.43 ENSDART00000019063
programmed cell death 10b
chr9_-_49860756 1.42 ENSDART00000044270
tetratricopeptide repeat domain 21B
chr19_+_42693855 1.41 ENSDART00000136873
cytoplasmic linker associated protein 2
chr1_+_36722122 1.41 ENSDART00000111566
transmembrane protein 184C
chr3_+_57997980 1.40 ENSDART00000168477
ENSDART00000193840
pyrroline-5-carboxylate reductase 1a
chr10_-_22828302 1.40 ENSDART00000079459
ENSDART00000100468
period circadian clock 1a
chr7_+_16509201 1.40 ENSDART00000173777
zinc finger, DHHC-type containing 13
chr11_+_44226200 1.39 ENSDART00000191417
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr6_+_37625787 1.38 ENSDART00000065122
tubulin, gamma complex associated protein 5
chr24_-_22756508 1.37 ENSDART00000035409
ENSDART00000146247
zinc finger, C2HC-type containing 1A
chr10_+_1668106 1.36 ENSDART00000142278
small G protein signaling modulator 1b
chr3_-_34337969 1.35 ENSDART00000151634
trinucleotide repeat containing 6C1
chr1_+_27867706 1.33 ENSDART00000102337
DnaJ (Hsp40) homolog, subfamily B, member 14
chr20_+_27087539 1.33 ENSDART00000062094
transmembrane protein 251
chr12_-_33558879 1.33 ENSDART00000161167
mbt domain containing 1
chr14_+_14043793 1.32 ENSDART00000164376
Ras-related GTP binding A
chr22_+_2300484 1.32 ENSDART00000106503
zinc finger protein 1180
chr8_-_52715911 1.32 ENSDART00000168241
tubulin, beta 2b
chr21_-_40173821 1.32 ENSDART00000180667
solute carrier organic anion transporter family, member 2B1
chr16_-_16590489 1.31 ENSDART00000190021
si:ch211-257p13.3
chr24_+_35911020 1.31 ENSDART00000088480
ATP-binding cassette, sub-family D (ALD), member 4
chr7_-_24204665 1.30 ENSDART00000167141
guanosine monophosphate reductase 2
chr3_+_46479913 1.30 ENSDART00000149755
tyrosine kinase 2
chr5_-_45894802 1.30 ENSDART00000097648
cytokine receptor family member b6
chr2_-_2096055 1.28 ENSDART00000126566
solute carrier family 22, member 23
chr5_-_55623443 1.27 ENSDART00000005671
ENSDART00000176341
heterogeneous nuclear ribonucleoprotein K, like
chr23_-_26120281 1.27 ENSDART00000133372
ENSDART00000103872
regulator of complement activation group 2 gene 1
chr4_+_4902392 1.26 ENSDART00000133866
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr18_+_11970987 1.25 ENSDART00000144111
si:dkeyp-2c8.3
chr17_-_19626357 1.24 ENSDART00000011432
receptor accessory protein 3a
chr21_-_14762944 1.24 ENSDART00000114096
arrestin domain containing 1b
chr12_+_33395748 1.24 ENSDART00000129458
fatty acid synthase
chr2_-_30200206 1.24 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr22_-_16403602 1.23 ENSDART00000183417
laminin, alpha 3
chr2_+_27651984 1.23 ENSDART00000126762
transmembrane protein 68
chr24_-_35707552 1.22 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr22_+_1586060 1.21 ENSDART00000160793
si:ch211-255f4.11
chr19_-_24125457 1.21 ENSDART00000080632
zgc:64022
chr12_-_33558727 1.21 ENSDART00000086087
mbt domain containing 1
chr22_+_12798569 1.21 ENSDART00000005720
signal transducer and activator of transcription 1a
chr22_-_16758438 1.21 ENSDART00000132829
PATJ, crumbs cell polarity complex component
chr1_-_54997746 1.20 ENSDART00000152666
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr23_-_10175898 1.19 ENSDART00000146185
keratin 5
chr9_+_48085039 1.19 ENSDART00000186734
si:ch73-54b5.2
chr8_-_52594111 1.18 ENSDART00000167667
si:ch73-199g24.2
chr7_+_41748693 1.18 ENSDART00000174379
ENSDART00000052168
histamine receptor H3
chr21_+_35296246 1.18 ENSDART00000076750
interleukin 12B, b
chr22_+_1734981 1.18 ENSDART00000158195
zinc finger protein 1159
chr10_-_26766780 1.18 ENSDART00000146666
MCF.2 cell line derived transforming sequence b
chr10_+_10636237 1.16 ENSDART00000136853
family with sequence similarity 163, member B
chr3_-_32902138 1.15 ENSDART00000144026
ENSDART00000083874
ENSDART00000145443
ENSDART00000148239
ENSDART00000134917
K(lysine) acetyltransferase 7a
chr6_-_19341184 1.15 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr5_-_41124241 1.14 ENSDART00000083561
myotubularin related protein 12
chr4_-_17642168 1.14 ENSDART00000007030
kelch-like family, member 42
chr17_-_36988455 1.14 ENSDART00000187180
ENSDART00000126823
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr24_-_11127493 1.14 ENSDART00000144066
myosin VIIA and Rab interacting protein
chr13_+_4225173 1.14 ENSDART00000058242
ENSDART00000143456
male-enhanced antigen 1
chr3_+_46762703 1.13 ENSDART00000133283
protein kinase C substrate 80K-H
chr2_+_36109002 1.12 ENSDART00000158978
T-cell receptor alpha joining 28
chr13_+_28705143 1.11 ENSDART00000183338
LIM domain binding 1a
chr7_+_31051603 1.11 ENSDART00000108721
tight junction protein 1a
chr20_-_51727860 1.11 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr11_+_25139495 1.11 ENSDART00000168368
si:ch211-25d12.7
chr4_-_77252368 1.11 ENSDART00000111941
zgc:174310
chr17_+_43468732 1.10 ENSDART00000055487
charged multivesicular body protein 3
chr7_-_51476276 1.10 ENSDART00000082464
NHS-like 2
chr20_-_1191910 1.10 ENSDART00000043218
ubiquitin-conjugating enzyme E2, J1
chr14_+_26796684 1.09 ENSDART00000187414
kelch-like family member 4
chr23_-_42810664 1.09 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr15_-_2652640 1.08 ENSDART00000146094
claudin f
chr1_+_12767318 1.08 ENSDART00000162652
protocadherin 10a
chr11_+_20899029 1.06 ENSDART00000163029
zgc:162182
chr8_+_20157798 1.06 ENSDART00000124809
acyl-CoA synthetase bubblegum family member 2
chr6_+_19689464 1.05 ENSDART00000164960
syntaxin 8
chr13_+_34689663 1.05 ENSDART00000133661
taspase, threonine aspartase, 1
chr2_+_3823813 1.05 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
Niemann-Pick disease, type C1
chr12_-_44043285 1.05 ENSDART00000163074
si:ch211-182p11.1
chr10_+_39304422 1.04 ENSDART00000019267
potassium inwardly-rectifying channel, subfamily J, member 1b
chr4_-_30422325 1.03 ENSDART00000158444
zinc finger protein 1114
chr11_+_38280454 1.03 ENSDART00000171496
si:dkey-166c18.1
chr23_+_32021803 1.02 ENSDART00000012963
trafficking protein particle complex 6b
chr1_-_14258409 1.02 ENSDART00000079359
phosphodiesterase 5A, cGMP-specific, a
chr2_-_36918709 1.02 ENSDART00000084876
zgc:153654
chr7_-_6351021 1.02 ENSDART00000159542
zgc:112234
chr12_+_14556092 1.02 ENSDART00000115237
beclin 1, autophagy related
chr10_-_105100 1.02 ENSDART00000145716
tetratricopeptide repeat domain 3
chr10_+_42169982 1.01 ENSDART00000190905

chr19_-_12404590 1.01 ENSDART00000103703
finTRIM family, member 56
chr6_-_28943056 1.01 ENSDART00000065138
TBC1 domain family, member 23
chr1_+_1896737 1.00 ENSDART00000152442
si:ch211-132g1.6
chr15_+_3808996 1.00 ENSDART00000110227
ring finger protein 14
chr16_-_22251414 1.00 ENSDART00000158500
ENSDART00000179998
ATPase phospholipid transporting 8B2
chr4_-_22310956 0.99 ENSDART00000162585
hematopoietic cell-specific Lyn substrate 1
chr3_-_21061931 0.99 ENSDART00000036741
family with sequence similarity 57, member Ba
chr8_-_39838660 0.99 ENSDART00000139266
finTRIM family, member 98
chr5_-_61797220 0.98 ENSDART00000079855
im:7138535
chr8_-_36399884 0.98 ENSDART00000108538
si:zfos-2070c2.3
chr6_-_44161262 0.97 ENSDART00000035513
SHQ1, H/ACA ribonucleoprotein assembly factor
chr12_-_23009312 0.97 ENSDART00000111801
mohawk homeobox a
chr16_+_43368572 0.96 ENSDART00000032778
ENSDART00000193897
ring finger protein 144B
chr7_+_60161002 0.96 ENSDART00000054007
solute carrier family 8 (sodium/calcium exchanger), member 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of elf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 1.7 GO:0035973 aggrephagy(GO:0035973)
0.5 1.4 GO:1903358 regulation of Golgi organization(GO:1903358)
0.5 2.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 1.3 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.4 7.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.4 1.5 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.4 1.4 GO:2000383 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.3 1.0 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.3 1.0 GO:1990403 embryonic brain development(GO:1990403)
0.3 2.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.3 2.8 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 0.8 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.3 1.6 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.2 0.7 GO:0042832 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.2 0.7 GO:0035046 pronuclear migration(GO:0035046)
0.2 1.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 6.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.2 0.8 GO:0045938 regulation of endocrine process(GO:0044060) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) endocrine hormone secretion(GO:0060986)
0.2 4.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 4.0 GO:0007020 microtubule nucleation(GO:0007020)
0.2 1.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 0.5 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.2 1.9 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.2 1.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 1.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 2.8 GO:0060021 palate development(GO:0060021)
0.1 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 1.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.1 0.5 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 1.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 6.6 GO:0006414 translational elongation(GO:0006414)
0.1 1.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.2 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.7 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 1.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.5 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 5.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.8 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.1 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.1 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.9 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.4 GO:0042542 response to hydrogen peroxide(GO:0042542) entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.5 GO:0021634 optic nerve formation(GO:0021634)
0.1 3.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.1 0.2 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 0.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 1.3 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 1.0 GO:0045445 myoblast differentiation(GO:0045445)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.4 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.7 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.1 1.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 2.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.1 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0006788 heme oxidation(GO:0006788)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.1 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.9 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.6 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988) synaptic membrane adhesion(GO:0099560)
0.0 0.8 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.0 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 1.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 2.0 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.5 GO:0021754 facial nucleus development(GO:0021754)
0.0 1.0 GO:0038202 TORC1 signaling(GO:0038202)
0.0 1.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 1.5 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.3 GO:0042552 myelination(GO:0042552)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.1 GO:0048278 vesicle docking(GO:0048278)
0.0 0.7 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.3 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 1.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 2.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 2.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 2.2 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 1.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 4.1 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.1 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 2.8 GO:0061008 hepaticobiliary system development(GO:0061008)
0.0 1.1 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.3 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 1.6 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 1.1 GO:0048916 posterior lateral line development(GO:0048916)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 3.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.3 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 1.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.2 GO:0016358 dendrite development(GO:0016358)
0.0 1.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.1 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.4 1.3 GO:1902560 GMP reductase complex(GO:1902560)
0.4 1.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.4 2.8 GO:0031931 TORC1 complex(GO:0031931)
0.3 1.7 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3 1.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.3 2.4 GO:0030897 HOPS complex(GO:0030897)
0.3 1.2 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.3 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.3 4.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 1.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 1.1 GO:0017177 glucosidase II complex(GO:0017177)
0.3 1.3 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 2.6 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 1.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 1.0 GO:0071203 WASH complex(GO:0071203)
0.2 3.3 GO:0005801 cis-Golgi network(GO:0005801)
0.2 1.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 2.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 1.4 GO:0045095 keratin filament(GO:0045095)
0.1 5.5 GO:0043204 perikaryon(GO:0043204)
0.1 0.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 3.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 5.1 GO:0031902 late endosome membrane(GO:0031902)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.7 GO:0000145 exocyst(GO:0000145)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 5.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.6 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.5 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 1.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 3.8 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 1.9 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.7 GO:0005874 microtubule(GO:0005874)
0.0 1.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.8 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0043621 protein self-association(GO:0043621)
0.4 4.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 1.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4 1.7 GO:0003796 lysozyme activity(GO:0003796)
0.3 4.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.3 1.2 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.3 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 1.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 2.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 2.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.7 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.2 1.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.8 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.2 1.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.9 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.2 2.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.5 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.2 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.7 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 2.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.4 GO:0008494 translation activator activity(GO:0008494)
0.2 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 6.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 2.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.6 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.4 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 5.1 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.1 0.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.8 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 2.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 3.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.5 GO:0008009 chemokine activity(GO:0008009)
0.1 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 1.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.9 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.0 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 3.3 GO:0008201 heparin binding(GO:0008201)
0.0 2.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 4.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.0 2.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 6.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 17.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 9.7 GO:0005525 GTP binding(GO:0005525)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.8 GO:0015631 tubulin binding(GO:0015631)
0.0 2.2 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 4.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.7 PID INSULIN PATHWAY Insulin Pathway
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 2.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.5 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs