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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for fosl2l

Z-value: 0.52

Motif logo

Transcription factors associated with fosl2l

Gene Symbol Gene ID Gene Info
ENSDARG00000092174 fos-like antigen 2 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch211-59d15.4dr11_v1_chr20_+_9211237_9211237-0.112.9e-01Click!

Activity profile of fosl2l motif

Sorted Z-values of fosl2l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_20381485 4.95 ENSDART00000131351
si:ch211-270n8.1
chr1_-_56176976 3.68 ENSDART00000052688
complement component c3a, duplicate 1
chr20_+_26880668 3.39 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr20_-_35578435 3.38 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr13_+_23988442 3.08 ENSDART00000010918
angiotensinogen
chr8_-_38201415 3.07 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr3_+_21189766 3.05 ENSDART00000078807
zgc:123295
chr4_-_9891874 2.90 ENSDART00000067193
adrenomedullin 2a
chr13_+_2908764 2.87 ENSDART00000162362
wu:fj16a03
chr16_+_23403602 2.83 ENSDART00000159848
S100 calcium binding protein W
chr25_+_10410620 2.60 ENSDART00000151886
ets homologous factor
chr7_+_33172066 2.24 ENSDART00000174013
si:ch211-194p6.12
chr8_+_8671229 2.23 ENSDART00000131963
ubiquitin specific peptidase 11
chr13_+_4671698 2.23 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
phospholipase A2, group XIIB
chr15_+_21202820 2.20 ENSDART00000154036
si:dkey-52d15.2
chr16_+_49005321 2.14 ENSDART00000160919

chr6_-_609880 2.14 ENSDART00000149248
ENSDART00000148867
ENSDART00000149414
ENSDART00000148552
ENSDART00000148391
lectin, galactoside-binding, soluble, 2b
chr6_+_54711306 2.11 ENSDART00000074605
plakophilin 1b
chr20_+_28364742 2.08 ENSDART00000103355
ras homolog family member V
chr8_+_6576940 2.04 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr7_+_19482084 1.97 ENSDART00000173873
si:ch211-212k18.7
chr22_+_38194151 1.93 ENSDART00000121965
ceruloplasmin
chr2_+_31671545 1.91 ENSDART00000145446
atypical chemokine receptor 4a
chr23_-_1017605 1.88 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr9_+_46745348 1.87 ENSDART00000025256
insulin-like growth factor binding protein 2b
chr8_+_22516728 1.85 ENSDART00000146013
si:ch211-261n11.3
chr23_-_1017428 1.72 ENSDART00000110588
ENSDART00000183158
cadherin 26, tandem duplicate 1
chr7_-_7398350 1.71 ENSDART00000012637
zgc:101810
chr19_-_7420867 1.69 ENSDART00000081741
RAB25, member RAS oncogene family a
chr1_-_25177086 1.69 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr4_+_16715267 1.65 ENSDART00000143849
plakophilin 2
chr3_+_4346854 1.59 ENSDART00000004273
si:dkey-73p2.3
chr8_+_1766206 1.58 ENSDART00000021820
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr24_+_24726956 1.52 ENSDART00000144574
ENSDART00000066628
mitochondrial fission regulator 1
chr17_+_6585333 1.49 ENSDART00000124293
adhesion G protein-coupled receptor F3a
chr4_+_25181572 1.49 ENSDART00000078529
ENSDART00000136643
Kin17 DNA and RNA binding protein
chr16_+_32136550 1.48 ENSDART00000147526
sphingosine kinase 2
chr3_-_48259289 1.46 ENSDART00000160717
zinc finger protein 750
chr5_+_22370167 1.46 ENSDART00000145163
si:dkey-27p18.7
chr15_+_42235449 1.46 ENSDART00000114801
ENSDART00000182053
sphingosine-1-phosphate phosphatase 2
chr7_+_39706004 1.45 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr3_-_4303262 1.43 ENSDART00000112819
si:dkey-73p2.2
chr24_-_33366188 1.42 ENSDART00000074161
solute carrier family 4 (anion exchanger), member 2b
chr8_-_18667693 1.42 ENSDART00000100516
signal transducing adaptor family member 2b
chr25_+_18583877 1.41 ENSDART00000148741
MET proto-oncogene, receptor tyrosine kinase
chr20_-_23439011 1.38 ENSDART00000022887
solute carrier family 10, member 4
chr3_+_46762703 1.37 ENSDART00000133283
protein kinase C substrate 80K-H
chr3_-_26017592 1.34 ENSDART00000030890
heme oxygenase 1a
chr20_-_34127415 1.33 ENSDART00000010028
prostaglandin-endoperoxide synthase 2b
chr24_+_38216340 1.31 ENSDART00000188561

chr25_+_32474031 1.31 ENSDART00000152124
sulfide quinone oxidoreductase
chr16_-_31598771 1.30 ENSDART00000016386
thyroglobulin
chr4_-_18775548 1.30 ENSDART00000141187
differentially expressed in FDCP 6c homolog
chr20_-_34670236 1.29 ENSDART00000033325
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr16_+_26547152 1.28 ENSDART00000141393
protein tyrosine phosphatase, non-receptor type 3
chr19_+_37120491 1.28 ENSDART00000032341
penta-EF-hand domain containing 1
chr3_+_32118670 1.27 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr7_-_29534001 1.25 ENSDART00000124028
annexin A2b
chr6_-_59357256 1.25 ENSDART00000074534
family with sequence similarity 210, member B
chr23_+_28378543 1.25 ENSDART00000145327
zgc:153867
chr8_-_11170114 1.25 ENSDART00000133532
si:ch211-204d2.4
chr15_+_3766101 1.24 ENSDART00000042580
ENSDART00000112698
ENSDART00000187035
ENSDART00000165571
ENSDART00000121752
zmp:0000000524
chr5_+_51026563 1.20 ENSDART00000050988
glucosaminyl (N-acetyl) transferase 4, core 2, a
chr19_+_24488403 1.19 ENSDART00000052421
thioredoxin interacting protein a
chr3_+_34121156 1.19 ENSDART00000174929
aldehyde dehydrogenase 3 family, member B1
chr7_-_30926030 1.18 ENSDART00000075421
sorbitol dehydrogenase
chr3_-_26017831 1.16 ENSDART00000179982
heme oxygenase 1a
chr3_-_39190317 1.15 ENSDART00000013167
retinol saturase (all-trans-retinol 13,14-reductase)
chr25_-_33275666 1.14 ENSDART00000193605

chr2_-_13691834 1.14 ENSDART00000186570

chr2_-_985417 1.12 ENSDART00000140540
si:ch211-241e1.3
chr19_-_7043355 1.10 ENSDART00000104845
TAP binding protein (tapasin), tandem duplicate 1
chr13_-_10945288 1.09 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
ATP-binding cassette, sub-family G (WHITE), member 8
chr14_+_33882973 1.09 ENSDART00000019396
chloride intracellular channel 2
chr24_+_38223618 1.08 ENSDART00000003495
immunoglobulin light 3 variable 2
chr7_+_14005111 1.06 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr17_-_15600455 1.05 ENSDART00000110272
ENSDART00000156911
si:ch211-266g18.9
chr4_-_76303301 1.05 ENSDART00000158504
zgc:174944
chr4_-_17822447 1.03 ENSDART00000185502
DnaJ (Hsp40) homolog, subfamily B, member 9b
chr7_+_69019851 1.03 ENSDART00000162891

chr25_-_11378623 1.02 ENSDART00000166586
ectodermal-neural cortex 2
chr23_-_45398622 1.02 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr25_+_8407892 1.00 ENSDART00000153536
mucin 5.2
chr4_-_76105527 1.00 ENSDART00000159108
zgc:110171
chr13_-_49585385 0.96 ENSDART00000165868
translocase of outer mitochondrial membrane 20
chr5_-_1047504 0.96 ENSDART00000159346
methyl-CpG binding domain protein 2
chr15_+_17343319 0.95 ENSDART00000018461
vacuole membrane protein 1
chr18_+_25225524 0.94 ENSDART00000055563
si:dkeyp-59c12.1
chr4_+_76973771 0.93 ENSDART00000142978
si:dkey-240n22.3
chr4_+_58667348 0.92 ENSDART00000186596
ENSDART00000180673

chr22_+_17399124 0.92 ENSDART00000145769
RAB GTPase activating protein 1-like
chr21_-_27338639 0.92 ENSDART00000130632
hypoxia-inducible factor 1, alpha subunit, like 2
chr19_-_7070691 0.91 ENSDART00000168755
TAP binding protein (tapasin), tandem duplicate 2
chr20_+_6543674 0.91 ENSDART00000134204
tensin 3, tandem duplicate 1
chr6_-_40842768 0.89 ENSDART00000076160
musculoskeletal, embryonic nuclear protein 1a
chr15_-_18197008 0.86 ENSDART00000147632
si:ch211-247l8.8
chr3_+_2754885 0.86 ENSDART00000188692

chr8_-_22288004 0.86 ENSDART00000100042
si:ch211-147a11.3
chr24_+_38208823 0.86 ENSDART00000187538
ENSDART00000190189

chr16_-_21785261 0.85 ENSDART00000078858
si:ch73-86n18.1
chr22_-_6884981 0.84 ENSDART00000124219

chr10_-_32877348 0.84 ENSDART00000018977
ENSDART00000133421
RAB guanine nucleotide exchange factor (GEF) 1
chr23_-_4704938 0.84 ENSDART00000067293
CCHC-type zinc finger, nucleic acid binding protein a
chr10_-_44482911 0.84 ENSDART00000085556
huntingtin interacting protein 1 related a
chr2_+_25378457 0.82 ENSDART00000089108
fibronectin type III domain containing 3Ba
chr24_+_38201089 0.81 ENSDART00000132338
immunoglobulin light 3 variable 2
chr4_-_75651505 0.81 ENSDART00000115143
si:dkey-71l4.2
chr4_+_75575252 0.81 ENSDART00000166536
si:ch211-227e10.1
chr4_+_58661331 0.80 ENSDART00000188763

chr21_+_22892836 0.80 ENSDART00000065565
ALG8, alpha-1,3-glucosyltransferase
chr12_-_17147473 0.78 ENSDART00000106035
STAM binding protein-like 1
chr4_+_68519945 0.78 ENSDART00000171148
si:dkey-16p6.1
chr13_-_33134611 0.78 ENSDART00000026280
pleckstrin 2
chr3_+_43955864 0.77 ENSDART00000168267

chr1_+_46598764 0.76 ENSDART00000053240
calcium binding protein 39-like
chr25_+_13498188 0.76 ENSDART00000015710
SNF related kinase b
chr13_+_19283936 0.76 ENSDART00000111462
eukaryotic translation initiation factor 3, subunit 10 (theta)
chr11_+_37905630 0.75 ENSDART00000170303
si:ch211-112f3.4
chr1_+_10318089 0.75 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr11_+_44617021 0.75 ENSDART00000158887
RNA binding motif protein 34
chr4_-_76186742 0.74 ENSDART00000163970
si:ch211-106j21.4
chr2_+_30379650 0.74 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr7_-_20103384 0.74 ENSDART00000052902
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr8_+_30501170 0.73 ENSDART00000137009
si:dkey-91m11.5
chr20_-_21994901 0.73 ENSDART00000004984
dishevelled associated activator of morphogenesis 1b
chr9_+_2762270 0.73 ENSDART00000123342
ENSDART00000001795
ENSDART00000177563
sp3a transcription factor
chr4_+_43225728 0.73 ENSDART00000158639
ENSDART00000141339
ENSDART00000137770
ENSDART00000166019
si:ch211-76m11.5
chr18_+_47313715 0.72 ENSDART00000138806
BARX homeobox 2
chr6_-_41091151 0.71 ENSDART00000154963
ENSDART00000153818
serine/arginine-rich splicing factor 3a
chr24_-_23998897 0.71 ENSDART00000130053
zmp:0000000991
chr8_-_30979494 0.71 ENSDART00000138959
si:ch211-251j10.3
chr6_+_48348415 0.71 ENSDART00000064826
Mov10 RISC complex RNA helicase a
chr19_-_12078583 0.70 ENSDART00000024193
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr4_+_60428812 0.70 ENSDART00000162049
si:dkey-16p6.1
chr4_+_357810 0.69 ENSDART00000163436
ENSDART00000103645
transmembrane protein 181
chr3_-_34816893 0.69 ENSDART00000084448
ENSDART00000154696
proteasome 26S subunit, non-ATPase 11a
chr23_+_30967686 0.69 ENSDART00000144485
si:ch211-197l9.2
chr21_+_19525141 0.69 ENSDART00000058489
granzyme A
chr8_-_38403018 0.68 ENSDART00000134100
sorbin and SH3 domain containing 3
chr4_-_71471302 0.66 ENSDART00000187687
si:ch211-76m11.5
chr18_-_13360106 0.66 ENSDART00000091512
c-Maf inducing protein
chr21_+_3901775 0.66 ENSDART00000053609
dolichyldiphosphatase 1
chr2_-_6519017 0.66 ENSDART00000181716
regulator of G protein signaling 1
chr8_+_5024468 0.66 ENSDART00000030938
adrenoceptor alpha 1Aa
chr13_+_12671513 0.65 ENSDART00000010517
eukaryotic translation initiation factor 4eb
chr3_+_32365811 0.65 ENSDART00000155967
adaptor-related protein complex 2, alpha 1 subunit
chr24_-_40009446 0.64 ENSDART00000087422
amine oxidase, copper containing 1
chr20_+_53522059 0.64 ENSDART00000147570
p21 protein (Cdc42/Rac)-activated kinase 6b
chr24_+_19415124 0.63 ENSDART00000186931
sulfatase 1
chr7_-_7764287 0.63 ENSDART00000173021
ENSDART00000113131
inturned planar cell polarity protein
chr4_+_71014655 0.62 ENSDART00000170837
si:dkeyp-80d11.14
chr23_+_42336084 0.61 ENSDART00000158959
ENSDART00000161812
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr1_-_10640748 0.61 ENSDART00000103550
zgc:174945
chr17_+_51744450 0.61 ENSDART00000190955
ENSDART00000149807
ornithine decarboxylase 1
chr8_+_39511932 0.61 ENSDART00000113511
leucine zipper, putative tumor suppressor 1
chr5_+_24059598 0.60 ENSDART00000051547
GABA(A) receptor-associated protein a
chr12_+_18234557 0.60 ENSDART00000130741
family with sequence similarity 20, member Cb
chr17_+_32623931 0.59 ENSDART00000144217
cathepsin Ba
chr1_+_57041549 0.59 ENSDART00000152198
si:ch211-1f22.16
chr23_-_36316352 0.59 ENSDART00000014840
nuclear factor, erythroid 2
chr1_+_46598502 0.58 ENSDART00000132861
calcium binding protein 39-like
chr18_-_37355666 0.58 ENSDART00000098914
Yes-associated protein 1
chr4_-_71470455 0.58 ENSDART00000172685
si:ch211-76m11.5
chr15_-_43978141 0.57 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr1_+_57176256 0.56 ENSDART00000152741
si:dkey-27j5.6
chr4_+_69712223 0.56 ENSDART00000163035
ENSDART00000164475
si:dkey-238o14.1
zgc:174944
chr7_-_26125092 0.56 ENSDART00000079364
small nuclear RNA activating complex, polypeptide 2
chr18_+_47313899 0.56 ENSDART00000192389
ENSDART00000189592
ENSDART00000184281
BARX homeobox 2
chr25_+_13205878 0.55 ENSDART00000162319
ENSDART00000162283
si:ch211-147m6.2
chr8_-_22288258 0.55 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
chr23_-_20361971 0.55 ENSDART00000133373
si:rp71-17i16.5
chr13_-_15982707 0.54 ENSDART00000186911
ENSDART00000181072
IKAROS family zinc finger 1 (Ikaros)
chr4_-_39487825 0.54 ENSDART00000161855
si:dkey-261o4.6
chr10_-_22970723 0.54 ENSDART00000182145
ENSDART00000100802

chr4_-_56103062 0.53 ENSDART00000165784
ENSDART00000190846
si:dkey-16p6.1
chr21_+_43199237 0.53 ENSDART00000151748
AF4/FMR2 family, member 4
chr23_+_42254960 0.53 ENSDART00000102980
zinc finger, CCHC domain containing 11
chr3_-_32590164 0.53 ENSDART00000151151
tetraspanin 4b
chr19_+_4051535 0.52 ENSDART00000167084
bloodthirsty-related gene family, member 24
chr2_+_11685742 0.51 ENSDART00000138562
growth regulation by estrogen in breast cancer-like
chr4_-_52783184 0.51 ENSDART00000172283
si:dkey-4j21.2
chr22_+_24603930 0.50 ENSDART00000180240
ENSDART00000164256

chr4_-_56673431 0.50 ENSDART00000161464
ENSDART00000191926
si:ch211-227p7.5
chr7_-_26262978 0.50 ENSDART00000137769
adaptor-related protein complex 1, sigma 1 subunit
chr4_-_39186893 0.50 ENSDART00000150371
ENSDART00000121804
ENSDART00000133901
si:ch211-22k7.9
chr4_-_33073382 0.50 ENSDART00000146414
si:dkeyp-4f2.1
chr20_-_26531850 0.50 ENSDART00000183317
ENSDART00000131994
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr4_-_34459615 0.50 ENSDART00000169144
ENSDART00000167022
si:ch211-64i20.3
chr4_+_70341246 0.49 ENSDART00000123408
si:ch211-76m11.3
chr16_-_33816082 0.49 ENSDART00000181769
R-spondin 1
chr4_+_36616118 0.48 ENSDART00000160058
ENSDART00000170506
si:dkey-151g22.1
chr4_-_38829098 0.48 ENSDART00000151932
si:dkey-59l11.10
chr25_-_31907590 0.47 ENSDART00000149707
ENSDART00000149471
eukaryotic translation initiation factor 3, subunit Ja
chr12_+_46967789 0.46 ENSDART00000114866
ornithine aminotransferase
chr5_-_49951106 0.46 ENSDART00000135954
family with sequence similarity 172, member A
chr4_+_70015788 0.46 ENSDART00000161133
si:dkey-3h2.4
chr4_-_34460301 0.46 ENSDART00000192977
si:ch211-64i20.3
chr17_+_51743908 0.46 ENSDART00000149039
ENSDART00000148869
ornithine decarboxylase 1
chr6_+_23935045 0.46 ENSDART00000162993
growth arrest and DNA-damage-inducible, alpha, b
chr10_+_38593645 0.46 ENSDART00000011573
matrix metallopeptidase 13a

Network of associatons between targets according to the STRING database.

First level regulatory network of fosl2l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.7 2.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.5 3.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.4 1.3 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.3 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.3 0.8 GO:0002188 translation reinitiation(GO:0002188)
0.3 1.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.2 1.0 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 1.5 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.2 3.1 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.2 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 1.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 1.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.2 2.2 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) arachidonate transport(GO:1903963)
0.2 0.6 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.2 GO:0019405 alditol catabolic process(GO:0019405)
0.1 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.4 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.6 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 1.1 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.7 GO:0045907 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460) positive regulation of vasoconstriction(GO:0045907)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 1.1 GO:0016486 peptide hormone processing(GO:0016486) embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.4 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.4 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.3 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.1 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.8 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 4.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.8 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 1.0 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.9 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.5 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.4 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 2.6 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.6 GO:0051492 regulation of stress fiber assembly(GO:0051492) actin filament network formation(GO:0051639)
0.0 1.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.8 GO:0048268 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) clathrin coat assembly(GO:0048268)
0.0 1.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.3 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 2.2 GO:0006956 complement activation(GO:0006956)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.6 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.6 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 2.3 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.6 GO:0001736 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.1 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 1.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.7 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.6 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.1 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.6 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.7 GO:0050922 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.5 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0017177 glucosidase II complex(GO:0017177)
0.3 0.8 GO:0043614 multi-eIF complex(GO:0043614)
0.1 1.7 GO:0014704 intercalated disc(GO:0014704)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 1.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 3.6 GO:0016342 catenin complex(GO:0016342)
0.1 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 2.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.0 29.2 GO:0005615 extracellular space(GO:0005615)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.8 GO:0030136 clathrin-coated vesicle(GO:0030136)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.4 1.3 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.4 2.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 1.7 GO:0019215 intermediate filament binding(GO:0019215)
0.3 1.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 0.7 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.2 1.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.1 GO:0016936 galactoside binding(GO:0016936)
0.2 1.9 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 3.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 2.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 1.3 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.5 GO:0035197 siRNA binding(GO:0035197)
0.1 2.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 11.5 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 5.7 GO:0045296 cadherin binding(GO:0045296)
0.1 1.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 1.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.0 GO:0045182 translation regulator activity(GO:0045182)
0.0 4.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 1.8 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 7.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.1 3.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 5.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 3.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis