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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxb1a

Z-value: 0.65

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Transcription factors associated with foxb1a

Gene Symbol Gene ID Gene Info
ENSDARG00000089042 forkhead box B1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxb1adr11_v1_chr25_-_34156152_341561520.706.1e-15Click!

Activity profile of foxb1a motif

Sorted Z-values of foxb1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_35446110 9.20 ENSDART00000058773
regulator of G protein signaling 16
chr16_-_43025885 7.53 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr23_-_27633730 6.27 ENSDART00000103639
ADP-ribosylation factor 3a
chr4_+_8797197 5.81 ENSDART00000158671
sulfotransferase family 4A, member 1
chr19_-_31522625 5.53 ENSDART00000158438
ENSDART00000035049
N-terminal EF-hand calcium binding protein 1
chr14_-_17599452 5.16 ENSDART00000080042
RAB33A, member RAS oncogene family
chr18_-_39702327 5.06 ENSDART00000149158
Dmx-like 2
chr13_-_21701323 4.88 ENSDART00000164112
si:dkey-191g9.7
chr11_-_29082175 4.66 ENSDART00000123245
immunoglobin superfamily, member 21a
chr25_-_25142387 4.60 ENSDART00000031814
tumor susceptibility 101a
chr22_+_20195280 4.25 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr14_-_34044369 4.24 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr9_+_22632126 4.14 ENSDART00000139434
ets variant 5a
chr1_+_16073887 4.10 ENSDART00000160270
tumor suppressor candidate 3
chr5_-_24000211 4.01 ENSDART00000188865
MAP7 domain containing 2a
chr16_-_12173554 3.92 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr6_-_13408680 3.82 ENSDART00000151566
formin-like 2b
chr17_-_42213285 3.64 ENSDART00000140549
NK2 homeobox 2a
chr3_+_19207176 3.63 ENSDART00000087803
relaxin 3a
chr7_-_31941670 3.61 ENSDART00000180929
ENSDART00000075389
brain-derived neurotrophic factor
chr21_+_17542473 3.53 ENSDART00000005750
ENSDART00000141326
stomatin
chr7_+_46252993 3.48 ENSDART00000167149
zinc finger protein 536
chr1_+_25801648 3.44 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr14_+_8504410 3.22 ENSDART00000123364
vascular endothelial growth factor Ba
chr9_-_6661657 3.18 ENSDART00000133178
ENSDART00000113914
ENSDART00000061593
POU class 3 homeobox 3a
chr7_+_52712807 3.13 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr24_-_22756508 2.97 ENSDART00000035409
ENSDART00000146247
zinc finger, C2HC-type containing 1A
chr3_-_13146631 2.91 ENSDART00000172460
protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_25438737 2.89 ENSDART00000134470
FH2 domain containing 1
chr3_+_25907266 2.71 ENSDART00000170324
ENSDART00000192633
target of myb1 membrane trafficking protein
chr3_+_24134418 2.58 ENSDART00000156204
si:ch211-246i5.5
chr5_-_13086616 2.53 ENSDART00000051664
yippee-like 1
chr16_+_25011994 2.52 ENSDART00000157312
zinc finger protein 1035
chr1_+_22851261 2.39 ENSDART00000193925
general transcription factor IIE, polypeptide 2, beta
chr1_-_25438934 2.38 ENSDART00000111686
FH2 domain containing 1
chr2_+_6885852 2.34 ENSDART00000016607
regulator of G protein signaling 5b
chr21_+_30662263 2.32 ENSDART00000154758
ENSDART00000138664
chloride channel, voltage-sensitive 5a
chr19_-_19025998 2.28 ENSDART00000186156
ENSDART00000163359
ENSDART00000167951
dynein, cytoplasmic 1, light intermediate chain 1
chr15_-_18138607 2.25 ENSDART00000176690

chr24_+_15897717 2.24 ENSDART00000105956
neuropilin (NRP) and tolloid (TLL)-like 1, like
chr24_-_37484123 2.24 ENSDART00000111623
clusterin associated protein 1
chr7_+_30875273 2.20 ENSDART00000173693
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr5_-_28767573 2.20 ENSDART00000158299
ENSDART00000043466
Tnf receptor-associated factor 2a
chr3_-_49138004 2.20 ENSDART00000167173
GIPC PDZ domain containing family, member 1
chr25_+_21178033 2.12 ENSDART00000041169
ELKS/RAB6-interacting/CAST family member 1a
chr12_-_19151708 2.11 ENSDART00000057124
thyrotrophic embryonic factor a
chr11_+_30162407 2.06 ENSDART00000190333
ENSDART00000127502
cyclin-dependent kinase-like 5
chr6_+_4229360 2.04 ENSDART00000191347
ENSDART00000130642

chr14_+_31493119 2.04 ENSDART00000006463
PHD finger protein 6
chr7_+_36898850 2.04 ENSDART00000113342
TOX high mobility group box family member 3
chr21_-_19906786 2.02 ENSDART00000136084
malignant fibrous histiocytoma amplified sequence 1
chr10_-_32880298 2.02 ENSDART00000138243
RAB guanine nucleotide exchange factor (GEF) 1
chr18_-_30020879 2.01 ENSDART00000162086
si:ch211-220f16.2
chr6_+_13730522 2.01 ENSDART00000153524
wingless-type MMTV integration site family, member 6a
chr25_-_25434479 2.00 ENSDART00000171589
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr4_+_12013043 2.00 ENSDART00000130692
cryptochrome circadian clock 1aa
chr17_-_20287530 2.00 ENSDART00000078703
ENSDART00000191289
adducin 3 (gamma) b
chr11_+_6819050 1.97 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr7_-_9803154 1.97 ENSDART00000055593
aldehyde dehydrogenase 1 family, member A3
chr5_-_38384289 1.97 ENSDART00000135260
misshapen-like kinase 1
chr16_+_11724230 1.91 ENSDART00000060266
carcinoembryonic antigen-related cell adhesion molecule 1
chr1_-_37383539 1.91 ENSDART00000127579
secretory calcium-binding phosphoprotein 1
chr9_-_46072805 1.84 ENSDART00000169682
histone deacetylase 4
chr20_-_39103119 1.79 ENSDART00000143379
regulator of calcineurin 2
chr20_-_19365875 1.79 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
chr5_+_36650096 1.76 ENSDART00000111414
alkB homolog 6
chr1_-_37383741 1.74 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr13_+_31070181 1.74 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
chr1_-_22851481 1.72 ENSDART00000054386
quinoid dihydropteridine reductase b1
chr14_-_17576391 1.70 ENSDART00000161355
ENSDART00000168959
ring finger protein 4
chr24_-_25574967 1.69 ENSDART00000189828
connector enhancer of kinase suppressor of Ras 2a
chr6_+_40671336 1.61 ENSDART00000111639
ENSDART00000186617
arginine-glutamic acid dipeptide (RE) repeats b
chr9_-_30494727 1.60 ENSDART00000148729
si:dkey-229b18.3
chr19_+_7549854 1.60 ENSDART00000138866
ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr24_+_19210001 1.59 ENSDART00000179373
ENSDART00000139299
zgc:162928
chr1_-_40411944 1.55 ENSDART00000144135
mastermind-like transcriptional coactivator 3
chr11_-_36475124 1.55 ENSDART00000165203
ubiquitin specific peptidase 48
chr16_-_21668082 1.54 ENSDART00000088513
guanine nucleotide binding protein-like 1
chr9_-_44905867 1.52 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
chr21_-_18824434 1.48 ENSDART00000156333
si:dkey-112m2.1
chr7_-_30227878 1.48 ENSDART00000173514
zinc finger protein 710b
chr18_+_36631923 1.47 ENSDART00000098980
zinc finger protein 296
chr5_-_52243424 1.45 ENSDART00000159078
endoplasmic reticulum aminopeptidase 2
chr6_-_51101834 1.43 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr5_-_66749535 1.43 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr23_+_31405497 1.40 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr14_-_33177935 1.33 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr5_-_19494048 1.31 ENSDART00000098795
methylmalonic aciduria (cobalamin deficiency) cblB type
chr16_-_12173399 1.30 ENSDART00000142574
calsyntenin 3
chr8_-_24113575 1.30 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr24_-_19718077 1.30 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr1_-_19502322 1.27 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr25_+_3677650 1.24 ENSDART00000154348
prion protein, related sequence 3
chr24_-_21620316 1.24 ENSDART00000112670
ubiquitin specific peptidase 12a
chr20_+_46741074 1.16 ENSDART00000145294
si:ch211-57i17.1
chr23_+_31000243 1.15 ENSDART00000085263
selenoprotein I
chr7_+_56472585 1.14 ENSDART00000135259
ENSDART00000073596
increased sodium tolerance 1 homolog (yeast)
chr18_-_44935174 1.13 ENSDART00000081025
peroxisomal biogenesis factor 16
chr13_+_29773153 1.10 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
paired box 2a
chr11_-_45420212 1.10 ENSDART00000182042
ENSDART00000163185
ankyrin repeat domain 13C
chr12_+_48480632 1.10 ENSDART00000158157
Rho GTPase activating protein 44
chr4_+_12013642 1.05 ENSDART00000067281
cryptochrome circadian clock 1aa
chr15_-_15910226 1.03 ENSDART00000154219
synergin, gamma
chr6_-_30683637 0.99 ENSDART00000065212
tetratricopeptide repeat domain 4
chr14_+_31493306 0.99 ENSDART00000138341
PHD finger protein 6
chr15_+_25528290 0.99 ENSDART00000123143
nuclear protein, ataxia-telangiectasia locus
chr6_-_43283122 0.97 ENSDART00000186022
FERM domain containing 4Ba
chr17_+_16755287 0.95 ENSDART00000080129
stonin 2
chr13_+_1944451 0.91 ENSDART00000125914
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr8_-_25716074 0.90 ENSDART00000007482
testis specific protein, Y-linked
chr8_+_13064750 0.88 ENSDART00000039878
SAP30 binding protein
chr18_-_5781922 0.87 ENSDART00000128722
si:ch73-167i17.6
chr2_+_33326522 0.87 ENSDART00000056655
Kruppel-like factor 17
chr14_-_24111292 0.86 ENSDART00000186611
cytoplasmic polyadenylation element binding protein 4a
chr17_-_42213822 0.80 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr15_+_20801253 0.77 ENSDART00000179387
aldehyde dehydrogenase 3 family, member A1
chr13_-_37465524 0.77 ENSDART00000100324
ENSDART00000147336
protein phosphatase 2, regulatory subunit B', epsilon isoform b
chr1_-_39909985 0.76 ENSDART00000181673
storkhead box 2a
chr14_-_9982603 0.75 ENSDART00000054687
interleukin 1 receptor accessory protein-like 2
chr5_-_14344647 0.74 ENSDART00000188456
tet methylcytosine dioxygenase 3
chr4_+_77908076 0.72 ENSDART00000168811
si:zfos-2131b9.2
chr21_-_30032706 0.71 ENSDART00000156721
PWWP domain containing 2A
chr25_+_28253844 0.68 ENSDART00000151891
Ca++-dependent secretion activator 2
chr6_-_51386656 0.66 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
protein tyrosine phosphatase, receptor type, t
chr7_-_32599669 0.66 ENSDART00000173752
potassium voltage-gated channel, shaker-related subfamily, member 4
chr11_+_18612166 0.64 ENSDART00000162694
nuclear receptor coactivator 3
chr19_+_14573998 0.64 ENSDART00000022076
family with sequence similarity 46, member Bb
chr22_+_26798853 0.59 ENSDART00000087576
ENSDART00000179780
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr2_+_16710889 0.59 ENSDART00000017852
UBX domain protein 7
chr17_+_37932706 0.59 ENSDART00000075941
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr25_+_22281441 0.58 ENSDART00000089516
stomatin (EPB72)-like 1
chr25_+_24616717 0.54 ENSDART00000089113
ankyrin repeat and BTB (POZ) domain containing 2b
chr1_-_23268013 0.54 ENSDART00000146575
replication factor C (activator 1) 1
chr16_+_18535618 0.53 ENSDART00000021596
retinoid x receptor, beta b
chr13_-_42400647 0.53 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr21_+_15601100 0.52 ENSDART00000180558
ENSDART00000145454
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr16_-_36748374 0.52 ENSDART00000133310
phosphoinositide-3-kinase, regulatory subunit 4
chr21_+_44684577 0.52 ENSDART00000099528
sprouty homolog 4 (Drosophila)
chr9_+_19489514 0.52 ENSDART00000152032
ENSDART00000114256
ENSDART00000190572
ENSDART00000147571
ENSDART00000151918
ENSDART00000152034
si:ch211-140m22.7
chr12_-_1361517 0.50 ENSDART00000188297

chr6_-_3998199 0.49 ENSDART00000059212
unc-50 homolog (C. elegans)
chr12_-_28537615 0.46 ENSDART00000067762
si:ch211-94l19.4
chr17_+_2130018 0.46 ENSDART00000193675
ENSDART00000110529
BUB1 mitotic checkpoint serine/threonine kinase Bb
chr5_-_67757188 0.41 ENSDART00000167168
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr2_-_43168292 0.41 ENSDART00000132588
cAMP responsive element modulator a
chr10_+_31951338 0.40 ENSDART00000019416
LHFPL tetraspan subfamily member 6
chr20_-_36617313 0.39 ENSDART00000172395
ENSDART00000152856
enabled homolog (Drosophila)
chr7_+_9308625 0.37 ENSDART00000084598
selenoprotein S
chr21_-_13661631 0.36 ENSDART00000184408
patatin-like phospholipase domain containing 7a
chr17_+_44030692 0.35 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr13_-_30645965 0.35 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr5_-_72324371 0.33 ENSDART00000006380
T-box 3a
chr16_-_34477805 0.31 ENSDART00000136546
serine incorporator 2, like
chr10_-_2788668 0.30 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr20_+_7584211 0.29 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr24_-_25461267 0.21 ENSDART00000105820
membrane-bound transcription factor peptidase, site 2
chr8_-_20862443 0.18 ENSDART00000147267
si:ch211-133l5.8
chr21_+_3928947 0.17 ENSDART00000149777
senataxin
chr3_+_46762703 0.17 ENSDART00000133283
protein kinase C substrate 80K-H
chr11_-_20987378 0.16 ENSDART00000110140
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_+_24740013 0.14 ENSDART00000126897
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr2_+_24786765 0.13 ENSDART00000141030
phosphodiesterase 4C, cAMP-specific a
chr8_-_13013123 0.13 ENSDART00000147802
DENN/MADD domain containing 2Da
chr11_+_6295370 0.13 ENSDART00000139882
RAN binding protein 3a
chr4_+_23125689 0.08 ENSDART00000077854
MDM2 oncogene, E3 ubiquitin protein ligase
chr11_+_10984293 0.05 ENSDART00000065933
integrin, beta 6
chr4_+_10721795 0.01 ENSDART00000136000
ENSDART00000067253
stabilin 2
chr13_-_18011168 0.01 ENSDART00000144813
membrane-associated ring finger (C3HC4) 8
chr8_+_17184602 0.00 ENSDART00000050228
ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of foxb1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
1.5 4.4 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.9 3.4 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.8 5.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.7 4.2 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.7 2.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.6 5.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 1.8 GO:0090299 regulation of neural crest formation(GO:0090299)
0.5 2.3 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.4 4.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.4 1.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 1.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.3 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 5.2 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.3 3.2 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.3 0.9 GO:0048785 hatching gland development(GO:0048785)
0.3 4.2 GO:0001964 startle response(GO:0001964)
0.3 2.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.3 2.1 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 1.3 GO:0031627 telomeric loop formation(GO:0031627)
0.2 1.2 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 4.1 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.6 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.9 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.2 5.8 GO:0051923 sulfation(GO:0051923)
0.2 2.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 2.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.7 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.6 GO:0061010 gall bladder development(GO:0061010)
0.1 1.1 GO:0021588 cerebellum formation(GO:0021588)
0.1 4.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.9 GO:0002931 response to ischemia(GO:0002931)
0.1 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 2.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 2.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 2.2 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 1.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 1.1 GO:0007032 endosome organization(GO:0007032)
0.1 3.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 2.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 2.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 2.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.3 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 1.7 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 2.1 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 1.1 GO:0007031 peroxisome organization(GO:0007031)
0.0 1.3 GO:0030901 midbrain development(GO:0030901)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.6 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 2.3 GO:0006821 chloride transport(GO:0006821)
0.0 2.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 1.4 GO:0016573 histone acetylation(GO:0016573)
0.0 1.0 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 9.1 GO:0006886 intracellular protein transport(GO:0006886)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 3.8 GO:0015031 protein transport(GO:0015031)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0043291 RAVE complex(GO:0043291)
0.7 2.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.5 2.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.3 2.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 4.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 4.2 GO:0031209 SCAR complex(GO:0031209)
0.2 6.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.2 2.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.3 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.6 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 3.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 9.9 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.0 1.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 13.1 GO:0005768 endosome(GO:0005768)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 7.9 GO:0098794 postsynapse(GO:0098794)
0.0 1.4 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 4.6 GO:0005912 adherens junction(GO:0005912)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.7 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 1.5 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 1.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 3.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.3 4.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 1.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.9 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2 3.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 2.4 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.2 1.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.7 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 2.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 4.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 5.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.2 GO:0004707 MAP kinase activity(GO:0004707)
0.1 3.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.7 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 2.0 GO:0019003 GDP binding(GO:0019003)
0.1 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 4.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.7 GO:0030276 clathrin binding(GO:0030276)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.6 GO:0005179 hormone activity(GO:0005179)
0.0 12.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 2.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 2.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 5.8 GO:0051015 actin filament binding(GO:0051015)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.8 GO:0051213 dioxygenase activity(GO:0051213)
0.0 1.7 GO:0008134 transcription factor binding(GO:0008134)
0.0 1.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.0 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 3.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels