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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxc1a+foxc1b

Z-value: 0.92

Motif logo

Transcription factors associated with foxc1a+foxc1b

Gene Symbol Gene ID Gene Info
ENSDARG00000055398 forkhead box C1b
ENSDARG00000091481 forkhead box C1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxc1bdr11_v1_chr20_+_26702377_267023770.251.4e-02Click!
foxc1adr11_v1_chr2_-_689047_6890470.065.8e-01Click!

Activity profile of foxc1a+foxc1b motif

Sorted Z-values of foxc1a+foxc1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_26064480 14.11 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
LIM domain binding 3b
chr11_+_11200550 13.75 ENSDART00000181339
ENSDART00000187116
myomesin 2a
chr12_-_26064105 13.34 ENSDART00000168825
LIM domain binding 3b
chr1_+_7540978 12.52 ENSDART00000147770
myosin, light polypeptide 3, skeletal muscle
chr1_-_45177373 12.39 ENSDART00000143142
ENSDART00000034549
zgc:111983
chr22_+_20720808 12.30 ENSDART00000171321
si:dkey-211f22.5
chr21_+_6556635 10.24 ENSDART00000139598
procollagen, type V, alpha 1
chr24_-_25428176 9.75 ENSDART00000090010
phosphate regulating endopeptidase homolog, X-linked
chr24_-_40726073 8.79 ENSDART00000168100
slow myosin heavy chain 2
chr6_-_10828880 7.99 ENSDART00000131458
ENSDART00000020261
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr22_-_10486477 7.41 ENSDART00000184366
asporin (LRR class 1)
chr25_+_20216159 7.37 ENSDART00000048642
troponin T2d, cardiac
chr20_-_35578435 6.87 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr22_-_10487490 6.47 ENSDART00000064798
asporin (LRR class 1)
chr1_-_14332283 6.40 ENSDART00000090025
Wolfram syndrome 1a (wolframin)
chr3_-_18030938 6.39 ENSDART00000013540
si:ch73-141c7.1
chr7_-_18691637 6.14 ENSDART00000183715
si:ch211-119e14.9
chr11_-_29946927 6.07 ENSDART00000165182
zgc:113276
chr18_-_16792561 6.01 ENSDART00000145546
adenosine monophosphate deaminase 3b
chr12_+_20641471 5.99 ENSDART00000133654
calcium binding and coiled-coil domain 2
chr21_-_22928214 5.97 ENSDART00000182760
duboraya
chr16_-_13992646 5.62 ENSDART00000139623
si:dkey-85k15.6
chr5_+_39087364 5.30 ENSDART00000004286
annexin A3a
chr16_-_12723324 5.15 ENSDART00000131915
SH3 domain binding kinase family, member 3
chr18_+_808911 5.13 ENSDART00000172518
cytochrome c oxidase subunit Vab
chr1_-_37383539 5.04 ENSDART00000127579
secretory calcium-binding phosphoprotein 1
chr1_-_45146834 4.91 ENSDART00000144997
si:ch211-239f4.6
chr6_-_51771634 4.88 ENSDART00000073847
bladder cancer associated protein
chr1_-_23274393 4.77 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
ribosomal protein L9
chr20_-_27311675 4.68 ENSDART00000026088
ENSDART00000148361
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr2_-_2642476 4.49 ENSDART00000124032
SERPINE1 mRNA binding protein 1b
chr14_-_2602445 4.44 ENSDART00000166910
eukaryotic translation termination factor 1a
chr2_-_43635777 4.38 ENSDART00000148633
integrin, beta 1b.1
chr3_-_43770876 4.31 ENSDART00000160162
zgc:92162
chr4_-_13502549 4.23 ENSDART00000140366
si:ch211-266a5.12
chr25_+_26798673 4.19 ENSDART00000157235
carbonic anhydrase XII
chr5_-_65000312 4.11 ENSDART00000192893
zgc:110283
chr7_-_17337233 4.08 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr17_+_45404758 4.05 ENSDART00000147557
T cell activation RhoGTPase activating protein a
chr8_-_36370552 3.99 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
chr17_-_53439866 3.98 ENSDART00000154826
c-myc binding protein
chr9_+_17309195 3.92 ENSDART00000048548
sciellin
chr20_+_38276690 3.91 ENSDART00000061437
chemokine (C-C motif) ligand 38, duplicate 6
chr2_+_37804235 3.85 ENSDART00000076321
leukotriene B4 receptor 2b
chr9_-_21918963 3.80 ENSDART00000090782
LIM domain 7a
chr16_-_13818061 3.78 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr23_-_42752387 3.77 ENSDART00000149781
si:ch73-217n20.1
chr1_+_45056371 3.77 ENSDART00000073689
ENSDART00000167309
bloodthirsty-related gene family, member 1
chr11_+_18183220 3.70 ENSDART00000113468

chr22_+_34616151 3.68 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
chr22_-_8860869 3.60 ENSDART00000166188

chr1_-_37383741 3.39 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr18_+_16986903 3.36 ENSDART00000142088
si:ch211-218c6.8
chr6_-_8480815 3.35 ENSDART00000162300
RAS protein activator like 3
chr16_-_42004544 3.14 ENSDART00000034544
caspase a
chr23_-_16737161 3.03 ENSDART00000132573
si:ch211-224l10.4
chr9_-_23994225 3.03 ENSDART00000140346
collagen, type VI, alpha 3
chr13_+_28417297 3.01 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr9_+_13985567 2.99 ENSDART00000102296
CD28 molecule
chr22_-_22147375 2.93 ENSDART00000149304
cell division cycle 34 homolog (S. cerevisiae) a
chr4_-_4387012 2.85 ENSDART00000191836
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr16_+_7662609 2.85 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
blood vessel epicardial substance
chr7_-_38790341 2.83 ENSDART00000159884
si:dkey-23n7.10
chr23_-_36316352 2.81 ENSDART00000014840
nuclear factor, erythroid 2
chr7_-_16598212 2.79 ENSDART00000128488
E2F transcription factor 8
chr20_+_38458084 2.77 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr10_+_15107886 2.74 ENSDART00000188047
ENSDART00000164095
secretory calcium-binding phosphoprotein 8
chr6_+_40629066 2.73 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr11_+_37250839 2.72 ENSDART00000170209
interleukin 17 receptor C
chr15_+_37973197 2.69 ENSDART00000156661
si:dkey-238d18.9
chr19_-_10730488 2.67 ENSDART00000126033
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 1
chr8_-_20243389 2.65 ENSDART00000184904
alkaline ceramidase 1
chr23_+_2185397 2.61 ENSDART00000109373
C1q and TNF related 7
chr16_-_24815091 2.59 ENSDART00000154269
ENSDART00000131025
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr3_-_34034498 2.55 ENSDART00000151145
immunoglobulin heavy variable 11-2
chr7_-_24373662 2.52 ENSDART00000173865
si:dkey-11k2.7
chr2_-_51500957 2.51 ENSDART00000172481
polymeric immunoglobulin receptor-like 3.5
chr3_+_59411956 2.50 ENSDART00000166982
SEC14-like lipid binding 1
chr4_-_67980261 2.48 ENSDART00000182305
si:ch211-223k15.1
chr9_-_24244383 2.47 ENSDART00000182407
caveolae associated protein 2a
chr4_-_11132617 2.41 ENSDART00000150250
si:dkey-21h14.9
chr19_+_4051695 2.41 ENSDART00000166368
bloodthirsty-related gene family, member 24
chr7_+_19482877 2.34 ENSDART00000077868
si:ch211-212k18.7
chr20_+_10723292 2.32 ENSDART00000152805
si:ch211-182e10.4
chr9_+_6255682 2.32 ENSDART00000149827
UDP-glucuronate decarboxylase 1
chr20_-_46817223 2.25 ENSDART00000100336
estrogen-related receptor gamma b
chr11_-_11331052 2.20 ENSDART00000081765
ENSDART00000160247
mitochondrial ribosomal protein L4
chr25_+_19238175 2.19 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
diphosphoinositol pentakisphosphate kinase 1b
chr15_-_36347858 2.19 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
chr3_-_34586403 2.15 ENSDART00000151515
septin 9a
chr5_-_57624425 2.13 ENSDART00000167892
zgc:193711
chr1_-_9109699 2.13 ENSDART00000147833
vascular associated protein
chr12_-_9438227 2.11 ENSDART00000003932
erb-b2 receptor tyrosine kinase 2
chr19_+_164013 2.08 ENSDART00000167379
capping protein regulator and myosin 1 linker 1
chr23_+_16910071 2.04 ENSDART00000104793
si:dkey-147f3.8
chr5_-_4219741 2.03 ENSDART00000100093
si:ch211-283g2.2
chr10_+_38512270 2.03 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr16_+_13818500 1.96 ENSDART00000135245
folliculin
chr14_-_41468892 1.92 ENSDART00000173099
ENSDART00000003170
MID1 interacting protein 1, like
chr6_-_39275793 1.88 ENSDART00000180477
ENSDART00000148531
Rho guanine nucleotide exchange factor (GEF) 25b
chr20_+_36812368 1.87 ENSDART00000062931
ABRA C-terminal like
chr10_-_302827 1.76 ENSDART00000157582
EMSY BRCA2-interacting transcriptional repressor
chr1_+_18550864 1.74 ENSDART00000142515
si:dkey-192k22.2
chr17_-_33415740 1.74 ENSDART00000135218
coiled-coil domain containing 28A
chr16_-_5721386 1.69 ENSDART00000136655
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr13_+_36680564 1.67 ENSDART00000136030
ENSDART00000006923
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr19_+_7930004 1.66 ENSDART00000160410
si:dkey-266f7.4
chr9_+_15893093 1.62 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
chr2_-_24554416 1.61 ENSDART00000052061
calponin 2
chr7_+_49695904 1.61 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr7_+_9981757 1.59 ENSDART00000113429
ENSDART00000173233
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr7_-_2004159 1.59 ENSDART00000181965
ENSDART00000173821
zgc:171424
zgc:171424
chr9_+_51180508 1.58 ENSDART00000138990
interferon induced with helicase C domain 1
chr18_+_33468099 1.57 ENSDART00000131769
vomeronasal 2 receptor, h9
chr12_+_2399130 1.56 ENSDART00000075179
V-set and transmembrane domain containing 4b
chr19_+_7929704 1.53 ENSDART00000147015
si:dkey-266f7.4
chr7_-_17591007 1.50 ENSDART00000171023

chr16_+_33938227 1.48 ENSDART00000166254
GPN-loop GTPase 2
chr14_-_38865800 1.47 ENSDART00000173047
glutathione reductase
chr14_+_16937997 1.45 ENSDART00000163013
ENSDART00000167856
LIM and calponin homology domains 1b
chr24_-_37338739 1.45 ENSDART00000146844
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr6_+_33931740 1.42 ENSDART00000130492
ENSDART00000151213
origin recognition complex, subunit 1
chr23_-_22113455 1.41 ENSDART00000142474
polyhomeotic homolog 2a (Drosophila)
chr8_+_54263946 1.41 ENSDART00000193119
transmembrane and coiled-coil domain family 1
chr22_+_26793389 1.39 ENSDART00000165381
Pim proto-oncogene, serine/threonine kinase, related 69
chr4_-_17353100 1.38 ENSDART00000134467
ENSDART00000189019
PARP1 binding protein
chr19_-_18667130 1.37 ENSDART00000164833
ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like 3
chr19_-_33370271 1.37 ENSDART00000132628
naked cuticle homolog 3, like
chr25_+_35891342 1.35 ENSDART00000147093
LSM14A mRNA processing body assembly factor a
chr21_-_17290941 1.35 ENSDART00000147993
growth factor independent 1B transcription repressor
chr7_+_19483277 1.34 ENSDART00000173750
si:ch211-212k18.7
chr22_+_6198742 1.33 ENSDART00000132889
si:dkey-19a16.11
chr14_+_30285613 1.32 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr22_+_38978084 1.32 ENSDART00000025482
Rho guanine nucleotide exchange factor (GEF) 3
chr21_-_45871866 1.32 ENSDART00000161716
La ribonucleoprotein domain family, member 1
chr7_+_53254234 1.31 ENSDART00000169830
thyroid hormone receptor interactor 4
chr22_-_23000815 1.31 ENSDART00000137111
protein tyrosine phosphatase, receptor type, C
chr5_+_37890521 1.30 ENSDART00000140207
transmembrane protease, serine 4b
chr21_+_18274825 1.30 ENSDART00000144322
ENSDART00000147768
WD repeat domain 5
chr13_-_36680531 1.29 ENSDART00000085298
L-2-hydroxyglutarate dehydrogenase
chr13_+_21600946 1.28 ENSDART00000144045
SH2 domain containing 4Ba
chr11_+_16138065 1.25 ENSDART00000188616
Pim proto-oncogene, serine/threonine kinase, related 204
chr6_+_52853384 1.25 ENSDART00000174155
ENSDART00000164391

chr15_+_436776 1.25 ENSDART00000008504
mediator complex subunit 17
chr14_+_7699443 1.23 ENSDART00000123139
bromodomain containing 8
chr4_+_74945557 1.23 ENSDART00000158533
nucleoporin 50
chr2_-_36914281 1.23 ENSDART00000008322
si:dkey-193b15.5
chr11_+_17984354 1.23 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr8_+_47817454 1.23 ENSDART00000144825
Pim proto-oncogene, serine/threonine kinase, related 185
chr6_-_34008827 1.22 ENSDART00000191183
ENSDART00000003701
ENSDART00000192502
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr21_-_39931285 1.20 ENSDART00000180010
ENSDART00000024407
transmembrane and immunoglobulin domain containing 1
chr4_-_25064510 1.20 ENSDART00000025153
GATA binding protein 3
chr8_+_12951155 1.20 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr8_-_13419049 1.20 ENSDART00000133656
Pim proto-oncogene, serine/threonine kinase, related 101
chr5_-_23705828 1.20 ENSDART00000189419
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr3_+_29641181 1.20 ENSDART00000151517
eukaryotic translation initiation factor 3, subunit D
chr8_-_13471916 1.19 ENSDART00000146558
Pim proto-oncogene, serine/threonine kinase, related 105
chr13_-_301309 1.17 ENSDART00000131747
chitin synthase 1
chr7_-_24838367 1.15 ENSDART00000139455
ENSDART00000012483
ENSDART00000131530
family with sequence similarity 113
chr9_+_12890161 1.15 ENSDART00000146477
si:ch211-167j6.4
chr17_+_21477892 1.15 ENSDART00000155309
phospholipase A2, group IVF, tandem duplicate 2
chr15_-_20468302 1.14 ENSDART00000018514
deltaC
chr21_-_2322102 1.14 ENSDART00000162867
zgc:66483
chr17_-_17764801 1.14 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr1_-_2061419 1.13 ENSDART00000058878
oxoglutarate (alpha-ketoglutarate) receptor 1a, tandem duplicate 3
chr12_+_695619 1.12 ENSDART00000161691
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr12_+_10443785 1.11 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr1_+_40158146 1.10 ENSDART00000145694
si:ch211-113e8.9
chr10_+_23520952 1.08 ENSDART00000125317
zmp:0000000937
chr1_+_35862550 1.08 ENSDART00000132118
si:ch211-194g2.4
chr16_-_31974482 1.08 ENSDART00000189073
serine/threonine/tyrosine kinase 1
chr15_+_47903864 1.08 ENSDART00000063835
orthodenticle homolog 5
chr9_+_18576047 1.04 ENSDART00000145174
laccase (multicopper oxidoreductase) domain containing 1
chr8_+_23788981 1.03 ENSDART00000144229
si:ch211-163l21.8
chr7_-_21925863 1.03 ENSDART00000191213
si:dkey-85k7.10
chr8_-_51340773 1.02 ENSDART00000060633
KAT8 regulatory NSL complex subunit 3
chr18_+_15706160 1.01 ENSDART00000131524
si:ch211-264e16.1
chr8_-_48770163 0.99 ENSDART00000160959
Pim proto-oncogene, serine/threonine kinase, related 184
chr17_-_33416020 0.99 ENSDART00000140149
coiled-coil domain containing 28A
chr11_-_38910527 0.99 ENSDART00000143105
Pim proto-oncogene, serine/threonine kinase, related 126
chr4_+_12342173 0.98 ENSDART00000161518
Pim proto-oncogene, serine/threonine kinase, related 214
chr7_-_32981559 0.96 ENSDART00000175614
plakophilin 3b
chr14_+_15484544 0.96 ENSDART00000188649

chr2_-_37537887 0.95 ENSDART00000143496
ENSDART00000025841
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr8_-_46525092 0.94 ENSDART00000030482
sulfotransferase family 1, cytosolic sulfotransferase 2
chr13_+_21601149 0.92 ENSDART00000179369
SH2 domain containing 4Ba
chr15_-_38009344 0.92 ENSDART00000157094
si:dkey-238d18.6
chr2_+_49644803 0.92 ENSDART00000160342
si:ch211-209f23.7
chr17_+_12265095 0.91 ENSDART00000153812
Pim proto-oncogene, serine/threonine kinase, related 168
chr9_+_12896340 0.91 ENSDART00000136417
si:ch211-167j6.5
chr23_-_44819100 0.89 ENSDART00000076373
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1
chr7_+_20030888 0.89 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr15_-_1590858 0.88 ENSDART00000081875
nanor
chr8_+_32747612 0.86 ENSDART00000142824
hemicentin 2
chr3_+_12784460 0.86 ENSDART00000168382
cytochrome P450, family 2, subfamily K, polypeptide 8
chr24_+_9372292 0.85 ENSDART00000082422
ENSDART00000191127
ENSDART00000180510
si:ch211-285f17.1
chr25_-_35101673 0.84 ENSDART00000140864
zgc:162611
chr10_+_22034477 0.83 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr5_-_67629263 0.76 ENSDART00000133753
zinc finger and BTB domain containing 20
chr9_-_7089303 0.76 ENSDART00000146609
cytochrome C oxidase assembly factor 5

Network of associatons between targets according to the STRING database.

First level regulatory network of foxc1a+foxc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
1.3 8.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
1.2 1.2 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
1.0 8.0 GO:0086009 membrane repolarization(GO:0086009)
0.9 4.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.7 2.8 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.7 2.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.6 2.8 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.5 2.1 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.4 2.7 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.4 6.0 GO:0032264 IMP salvage(GO:0032264)
0.4 1.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.3 2.3 GO:0032475 otolith formation(GO:0032475)
0.3 4.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.3 6.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 12.3 GO:0030199 collagen fibril organization(GO:0030199)
0.3 4.3 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3 2.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 1.6 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.2 3.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.7 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 2.6 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.2 2.8 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.2 1.2 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 1.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 1.1 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.2 0.6 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 0.8 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.2 1.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 1.3 GO:0061055 myotome development(GO:0061055)
0.2 1.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.5 GO:0048211 Golgi vesicle docking(GO:0048211)
0.2 1.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 1.4 GO:0034063 stress granule assembly(GO:0034063)
0.2 2.2 GO:0006020 inositol metabolic process(GO:0006020)
0.2 2.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 6.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 7.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 4.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.9 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 1.4 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.1 1.0 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 1.0 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 5.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 3.1 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 12.3 GO:0006936 muscle contraction(GO:0006936)
0.1 3.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 2.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.3 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 9.7 GO:0016485 protein processing(GO:0016485)
0.1 3.4 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 0.3 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.1 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.4 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 4.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 3.0 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 3.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 27.4 GO:0061061 muscle structure development(GO:0061061)
0.1 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 4.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 3.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 3.8 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.0 3.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.6 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.7 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 3.9 GO:0008544 epidermis development(GO:0008544)
0.0 10.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.7 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 3.8 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 1.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 4.9 GO:0072594 establishment of protein localization to organelle(GO:0072594)
0.0 1.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.3 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.4 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.9 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.8 GO:0009617 response to bacterium(GO:0009617)
0.0 3.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 5.9 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.0 0.7 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.2 GO:0005588 collagen type V trimer(GO:0005588)
0.9 4.4 GO:0018444 translation release factor complex(GO:0018444)
0.8 3.1 GO:0061702 inflammasome complex(GO:0061702)
0.7 13.8 GO:0031430 M band(GO:0031430)
0.6 27.5 GO:0031941 filamentous actin(GO:0031941)
0.4 1.4 GO:0016460 myosin II complex(GO:0016460)
0.3 2.7 GO:0031526 brush border membrane(GO:0031526)
0.3 3.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 2.2 GO:0030428 cell septum(GO:0030428)
0.2 3.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.7 GO:0070209 ASTRA complex(GO:0070209)
0.2 1.2 GO:0070847 core mediator complex(GO:0070847)
0.2 7.4 GO:0005861 troponin complex(GO:0005861)
0.2 7.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 4.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 1.0 GO:0044545 NSL complex(GO:0044545)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 6.9 GO:0016459 myosin complex(GO:0016459)
0.1 1.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 3.7 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.0 4.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 5.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 4.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 3.0 GO:0005581 collagen trimer(GO:0005581)
0.0 2.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0005770 late endosome(GO:0005770)
0.0 2.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
1.4 27.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
1.1 3.4 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.9 4.4 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 6.4 GO:0048039 ubiquinone binding(GO:0048039)
0.7 7.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.6 3.9 GO:0004974 leukotriene receptor activity(GO:0004974)
0.5 2.2 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.5 6.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 5.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.5 15.9 GO:0005518 collagen binding(GO:0005518)
0.4 2.6 GO:0017040 ceramidase activity(GO:0017040)
0.4 5.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.4 1.2 GO:0098808 mRNA cap binding(GO:0098808)
0.4 1.4 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.3 2.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.3 1.5 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.3 2.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 2.2 GO:0004100 chitin synthase activity(GO:0004100)
0.2 5.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 2.7 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 2.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 3.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.6 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.2 2.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 2.8 GO:0030552 cAMP binding(GO:0030552)
0.2 1.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 4.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.4 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 2.1 GO:0033691 sialic acid binding(GO:0033691)
0.1 3.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 10.2 GO:0008201 heparin binding(GO:0008201)
0.1 1.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 4.8 GO:0019843 rRNA binding(GO:0019843)
0.1 0.3 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 3.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 11.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 3.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 22.5 GO:0051015 actin filament binding(GO:0051015)
0.1 1.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 2.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 4.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 5.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 4.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 13.3 NABA COLLAGENS Genes encoding collagen proteins
0.2 9.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 3.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.4 2.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 4.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 11.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 1.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 2.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 6.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 2.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors