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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxj1a+foxj1b

Z-value: 1.02

Motif logo

Transcription factors associated with foxj1a+foxj1b

Gene Symbol Gene ID Gene Info
ENSDARG00000088290 forkhead box J1b
ENSDARG00000101919 forkhead box J1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxj1adr11_v1_chr3_+_60716904_60716904-0.704.5e-15Click!
foxj1bdr11_v1_chr12_+_20149305_20149311-0.683.1e-14Click!

Activity profile of foxj1a+foxj1b motif

Sorted Z-values of foxj1a+foxj1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_7391400 13.72 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr4_+_7391110 12.60 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr7_+_22637515 10.96 ENSDART00000158698
si:dkey-112a7.5
chr22_+_19553390 10.55 ENSDART00000061739
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr25_-_13188678 10.34 ENSDART00000125754
si:ch211-147m6.1
chr21_-_22951604 9.34 ENSDART00000083449
ENSDART00000180129
duboraya
chr23_-_5683147 8.52 ENSDART00000102766
ENSDART00000067351
troponin T type 2a (cardiac)
chr1_+_53945934 8.52 ENSDART00000052838
actin, alpha 1a, skeletal muscle
chr16_-_45235947 7.99 ENSDART00000164436
si:dkey-33i11.4
chr4_-_16353733 7.99 ENSDART00000186785
lumican
chr4_-_12795436 7.69 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr25_+_19734038 7.19 ENSDART00000067354
zgc:101783
chr6_-_55864687 7.14 ENSDART00000160991
cytochrome P450, family 24, subfamily A, polypeptide 1
chr18_+_35842933 6.89 ENSDART00000151587
ENSDART00000131121
protein phosphatase 1, regulatory subunit 13 like
chr15_+_34069746 6.83 ENSDART00000163513
ADP-ribosylation factor-like 4aa
chr17_-_6451801 6.66 ENSDART00000064700
alpha-L-fucosidase 2
chr14_-_36799280 6.57 ENSDART00000168615
ring finger protein 130
chr19_+_18739085 6.50 ENSDART00000188868
sperm acrosome associated 4 like
chr4_-_12795030 6.45 ENSDART00000150427
beta-2-microglobulin
chr21_-_5881344 6.42 ENSDART00000009241
ribosomal protein L35
chr14_-_35462148 6.32 ENSDART00000045809
sushi-repeat containing protein, X-linked 2
chr12_-_8070969 6.18 ENSDART00000020995
transmembrane protein 26b
chr8_-_30791266 6.13 ENSDART00000062220
glutathione S-transferase theta 1a
chr22_-_28653074 6.11 ENSDART00000154717
collagen, type VIII, alpha 1b
chr4_-_6373735 6.01 ENSDART00000140100
si:ch73-156e19.1
chr25_+_8356707 5.95 ENSDART00000153708
mucin 5.1, oligomeric mucus/gel-forming
chr8_+_10305400 5.82 ENSDART00000172400
Pim-1 proto-oncogene, serine/threonine kinase
chr12_+_17100021 5.79 ENSDART00000177923
actin, alpha 2, smooth muscle, aorta
chr17_-_23709347 5.74 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr1_+_36651059 5.49 ENSDART00000187475
endothelin receptor type Aa
chr19_-_24958393 5.46 ENSDART00000098592
si:ch211-195b13.6
chr8_+_23034718 5.45 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr8_-_30791089 5.39 ENSDART00000147332
glutathione S-transferase theta 1a
chr7_-_26270014 5.14 ENSDART00000079347
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr2_+_55365727 4.99 ENSDART00000162943

chr17_+_15297398 4.99 ENSDART00000156574
si:ch211-270g19.5
chr16_-_24195252 4.86 ENSDART00000136205
ENSDART00000048599
ENSDART00000161547
ribosomal protein S19
chr1_-_26702930 4.84 ENSDART00000109297
ENSDART00000152389
forkhead box E1
chr24_+_9298198 4.79 ENSDART00000165780
OTU deubiquitinase 1
chr25_-_13188214 4.74 ENSDART00000187298
si:ch211-147m6.1
chr18_-_48550426 4.73 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr24_-_37640705 4.69 ENSDART00000066583
zgc:112496
chr14_+_15155684 4.67 ENSDART00000167966
zgc:158852
chr13_-_31647323 4.62 ENSDART00000135381
SIX homeobox 4a
chr20_+_15552657 4.61 ENSDART00000063912
Jun proto-oncogene, AP-1 transcription factor subunit
chr24_-_31306724 4.59 ENSDART00000165399
acid phosphatase 5b, tartrate resistant
chr21_+_10577527 4.56 ENSDART00000165070
ENSDART00000127963
collagen and calcium binding EGF domains 1
chr4_+_5842433 4.54 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr21_-_3796461 4.54 ENSDART00000021976
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr7_-_28658143 4.45 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr17_-_27273296 4.36 ENSDART00000077087
inhibitor of DNA binding 3
chr23_-_1571682 4.33 ENSDART00000013635
F-box protein 30b
chr22_-_37686966 4.25 ENSDART00000192217
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr11_-_6048490 4.15 ENSDART00000066164
plasmalemma vesicle associated protein b
chr21_-_11632403 4.03 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr25_-_13202208 3.97 ENSDART00000168155
si:ch211-194m7.4
chr12_-_11457625 3.96 ENSDART00000012318
HtrA serine peptidase 1b
chr7_-_28549361 3.94 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
suppression of tumorigenicity 5
chr24_+_37640626 3.87 ENSDART00000008047
WD repeat domain 24
chr13_-_43149063 3.84 ENSDART00000099601
V-set immunoregulatory receptor
chr17_-_20167206 3.83 ENSDART00000104874
ENSDART00000191995
prolyl 4-hydroxylase, alpha polypeptide I b
chr19_+_30990815 3.79 ENSDART00000134645
syncoilin, intermediate filament protein
chr11_-_183328 3.72 ENSDART00000168562
advillin
chr25_+_37435720 3.69 ENSDART00000164390
charged multivesicular body protein 1A
chr2_+_38271392 3.67 ENSDART00000042100
homeobox and leucine zipper encoding a
chr14_+_26439227 3.60 ENSDART00000054183
G protein-coupled receptor 137
chr12_+_25775734 3.59 ENSDART00000024415
ENSDART00000149198
endothelial PAS domain protein 1a
chr16_+_33143503 3.58 ENSDART00000058471
ENSDART00000179385
rhomboid, veinlet-like 2 (Drosophila)
chr15_+_6661343 3.53 ENSDART00000160136
NOP53 ribosome biogenesis factor
chr20_+_25552057 3.51 ENSDART00000102913
cytochrome P450, family 2, subfamily V, polypeptide 1
chr14_+_30910114 3.48 ENSDART00000187166
ENSDART00000078187
forkhead box O4
chr5_-_34993242 3.48 ENSDART00000134516
ENSDART00000051295
basic transcription factor 3
chr23_+_7692042 3.41 ENSDART00000018512
protein O-fucosyltransferase 1
chr23_+_10469955 3.35 ENSDART00000140557
tensin 2a
chr6_-_37745508 3.25 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr15_-_25527580 3.24 ENSDART00000167005
ENSDART00000157498
hypoxia-inducible factor 1, alpha subunit, like
chr3_+_29510818 3.22 ENSDART00000055407
ENSDART00000193743
ENSDART00000123619
Rac family small GTPase 2
chr24_+_19542323 3.19 ENSDART00000140379
ENSDART00000142830
sulfatase 1
chr20_-_48172556 3.18 ENSDART00000097888

chr3_+_32671146 3.15 ENSDART00000039466
ring finger protein 25
chr22_-_2959005 3.15 ENSDART00000040701
inhibitor of growth family, member 5a
chr18_-_17399291 3.14 ENSDART00000192075
ENSDART00000060949
ENSDART00000188506
zinc finger protein, FOG family member 1
chr23_-_27123171 3.11 ENSDART00000023218
ENSDART00000146467
signal transducer and activator of transcription 6, interleukin-4 induced
chr7_-_3912905 3.09 ENSDART00000143864
si:dkey-88n24.10
chr7_-_28611145 3.08 ENSDART00000054366
signal peptide, CUB domain, EGF-like 2
chr20_+_26881600 3.07 ENSDART00000174799
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_-_1827575 3.07 ENSDART00000171193
mutated in colorectal cancers
chr10_-_3416258 3.03 ENSDART00000005168
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr23_+_25354856 3.02 ENSDART00000109023
ENSDART00000147440
formin-like 3
chr2_+_21000334 3.00 ENSDART00000062563
ENSDART00000147809
ras responsive element binding protein 1b
chr15_-_17960228 2.96 ENSDART00000155898
pleckstrin homology-like domain, family B, member 1b
chr17_-_26867725 2.91 ENSDART00000153590
si:dkey-221l4.10
chr20_+_53368611 2.89 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr23_-_17450746 2.88 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tumor protein D52-like 2b
chr9_-_11550711 2.85 ENSDART00000093343
FEV (ETS oncogene family)
chr18_-_46280578 2.84 ENSDART00000131724
phospholipase D family, member 3
chr20_+_6142433 2.84 ENSDART00000054084
ENSDART00000136986
transthyretin (prealbumin, amyloidosis type I)
chr10_+_41199660 2.82 ENSDART00000125314
adrenoceptor beta 3b
chr7_-_30127082 2.80 ENSDART00000173749
alpha-kinase 3b
chr19_-_32600638 2.78 ENSDART00000143497
zgc:91944
chr24_-_19718077 2.78 ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr5_-_66160415 2.76 ENSDART00000073895
membrane bound O-acyltransferase domain containing 4
chr21_-_20840714 2.76 ENSDART00000144861
ENSDART00000139430
complement component 6
chr17_+_53284040 2.75 ENSDART00000165368
ataxin 3
chr16_-_26731928 2.71 ENSDART00000135860
ring finger protein 41, like
chr16_+_26732086 2.69 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr3_-_13546610 2.67 ENSDART00000159647
amidohydrolase domain containing 2
chr25_+_37435335 2.64 ENSDART00000171602
charged multivesicular body protein 1A
chr1_+_9153141 2.63 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr7_-_24112484 2.63 ENSDART00000111923
ajuba LIM protein
chr10_-_42237304 2.61 ENSDART00000140341
transcription factor 7 like 1a
chr11_+_18612421 2.61 ENSDART00000110621
nuclear receptor coactivator 3
chr17_+_25519089 2.58 ENSDART00000041721
crystallin beta-gamma domain containing 1a
chr19_-_46018152 2.57 ENSDART00000159206
KRIT1, ankyrin repeat containing
chr13_-_21650404 2.49 ENSDART00000078352
tetraspanin 14
chr3_-_40664868 2.49 ENSDART00000138783
ENSDART00000178567
ring finger protein 216
chr13_+_18533005 2.47 ENSDART00000136024
finTRIM family, member 14-like
chr18_+_20226843 2.47 ENSDART00000100632
transducin-like enhancer of split 3a
chr23_+_24598910 2.47 ENSDART00000126510
ENSDART00000078796
KAT8 regulatory NSL complex subunit 2
chr12_-_28537615 2.46 ENSDART00000067762
si:ch211-94l19.4
chr12_+_28117365 2.39 ENSDART00000066290
urotensin 2 receptor
chr15_-_44052927 2.38 ENSDART00000166209
wu:fb44b02
chr2_+_19195841 2.37 ENSDART00000163137
ENSDART00000161095
ELOVL fatty acid elongase 1a
chr19_+_33476557 2.33 ENSDART00000181800
triple QxxK/R motif containing
chr15_+_34675660 2.32 ENSDART00000009127
lymphotoxin alpha (TNF superfamily, member 1)
chr23_-_45398622 2.32 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr3_-_36419641 2.31 ENSDART00000173545
component of oligomeric golgi complex 1
chr5_+_12528693 2.29 ENSDART00000051670
replication factor C (activator 1) 5
chr2_+_19633493 2.27 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr7_+_46003449 2.24 ENSDART00000159700
ENSDART00000173625
si:ch211-260e23.9
chr6_-_43792179 2.22 ENSDART00000160849
forkhead box P1b
chr5_-_19014589 2.21 ENSDART00000002624
RAN binding protein 1
chr25_+_28555584 2.18 ENSDART00000157046
si:ch211-190o6.3
chr10_+_28428222 2.18 ENSDART00000135003
si:ch211-222e20.4
chr15_+_31886284 2.14 ENSDART00000156706
furry homolog a (Drosophila)
chr16_+_22587661 2.13 ENSDART00000129612
ENSDART00000142241
Src homology 2 domain containing E
chr10_+_40836378 2.12 ENSDART00000085792
tripartite motif containing 69
chr23_-_31633201 2.10 ENSDART00000143335
ENSDART00000053531
solute carrier family 2 (facilitated glucose transporter), member 12
chr7_+_57108823 2.09 ENSDART00000184943
ENSDART00000055956
enolase superfamily member 1
chr10_+_11260170 2.08 ENSDART00000155742
hydroxysteroid dehydrogenase like 2
chr15_-_23647078 2.07 ENSDART00000059366
creatine kinase, muscle b
chr23_+_24085531 2.04 ENSDART00000139710
tubulin tyrosine ligase-like family, member 10
chr8_+_49570884 2.04 ENSDART00000182117
ENSDART00000108613
RAS and EF-hand domain containing
chr6_-_9695294 2.01 ENSDART00000162728
NOP58 ribonucleoprotein homolog (yeast)
chr25_-_37435060 2.01 ENSDART00000102855
ENSDART00000148566
pyruvate dehydrogenase complex, component X
chr14_+_16937997 1.99 ENSDART00000163013
ENSDART00000167856
LIM and calponin homology domains 1b
chr6_+_51824596 1.98 ENSDART00000149003
R-spondin 4
chr10_+_22775253 1.97 ENSDART00000190141
transmembrane protein 88 a
chr14_-_28001986 1.95 ENSDART00000054115
TSC22 domain family, member 3
chr13_-_7233811 1.95 ENSDART00000162026
ninein-like
chr7_+_4694924 1.93 ENSDART00000144873
si:ch211-225k7.3
chr3_+_25216790 1.92 ENSDART00000156544
C1q and TNF related 6a
chr15_+_30158652 1.90 ENSDART00000190682
nemo-like kinase, type 2
chr8_+_49065348 1.90 ENSDART00000032277
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr18_-_24988645 1.89 ENSDART00000136434
ENSDART00000085735
chromodomain helicase DNA binding protein 2
chr1_-_30510839 1.87 ENSDART00000168189
ENSDART00000174868
insulin-like growth factor 2 mRNA binding protein 2b
chr14_-_29799993 1.87 ENSDART00000133775
ENSDART00000005568
PDZ and LIM domain 3b
chr25_-_34740627 1.85 ENSDART00000137665
fibroblast growth factor receptor substrate 2b
chr7_+_24165371 1.85 ENSDART00000173472
si:ch211-216p19.5
chr15_-_28805493 1.84 ENSDART00000179617
CD3e molecule, epsilon associated protein
chr22_+_37631234 1.80 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr2_+_19522082 1.79 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr7_-_13906409 1.78 ENSDART00000062257
solute carrier family 39 (zinc transporter), member 1
chr4_-_17725008 1.78 ENSDART00000016658
choline phosphotransferase 1
chr19_+_619200 1.76 ENSDART00000050125
nucleoporin like 2
chr13_+_35635672 1.73 ENSDART00000148481
thrombospondin 2a
chr8_-_33154677 1.70 ENSDART00000133300
zinc finger and BTB domain containing 34
chr6_+_32834760 1.70 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr10_-_17501528 1.67 ENSDART00000144847
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr25_-_26893006 1.67 ENSDART00000006709
dihydrolipoamide dehydrogenase
chr17_+_24111392 1.65 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr22_+_11520249 1.64 ENSDART00000063147
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr20_-_26383368 1.64 ENSDART00000024518
ENSDART00000087844
estrogen receptor 1
chr3_+_46762703 1.63 ENSDART00000133283
protein kinase C substrate 80K-H
chr2_-_19576640 1.62 ENSDART00000141021
Pim proto-oncogene, serine/threonine kinase, related 51
chr10_+_23099890 1.62 ENSDART00000135890
si:dkey-175g6.5
chr2_-_17492080 1.62 ENSDART00000024302
lysine (K)-specific demethylase 4A, genome duplicate b
chr11_+_25430851 1.61 ENSDART00000164999
ENSDART00000126403
si:dkey-13a21.4
chr22_-_9714593 1.61 ENSDART00000188282
si:dkey-286j17.4
chr4_+_16725960 1.60 ENSDART00000034441
t-complex 11, testis-specific-like 2
chr19_+_4051535 1.60 ENSDART00000167084
bloodthirsty-related gene family, member 24
chr21_+_3796620 1.60 ENSDART00000099535
ENSDART00000144515
SPOUT domain containing methyltransferase 1
chr16_-_7228276 1.59 ENSDART00000149030
5'-nucleotidase, cytosolic IIIA
chr1_+_11107688 1.59 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr7_-_60831082 1.59 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr8_-_22288258 1.56 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
chr10_-_14929392 1.56 ENSDART00000137430
SMAD family member 2
chr23_+_38159715 1.56 ENSDART00000137969
zgc:112994
chr10_-_35257458 1.56 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr17_+_6667441 1.56 ENSDART00000123503
ENSDART00000180381
ENSDART00000156140
structural maintenance of chromosomes 6
chr6_-_18228358 1.54 ENSDART00000167937
prolyl 4-hydroxylase, beta polypeptide
chr20_-_2641233 1.51 ENSDART00000145335
ENSDART00000133121
BUB1 mitotic checkpoint serine/threonine kinase
chr6_+_40922572 1.50 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr20_-_18794789 1.49 ENSDART00000003834
cerebral cavernous malformation 2
chr17_+_43843536 1.49 ENSDART00000164097

chr21_-_11856143 1.47 ENSDART00000151204
ubiquitin-conjugating enzyme E2R 2
chr19_-_10915898 1.47 ENSDART00000163179
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr7_+_4694762 1.46 ENSDART00000132862
si:ch211-225k7.3
chr7_-_50367326 1.43 ENSDART00000141926
protein regulator of cytokinesis 1b
chr9_+_11293830 1.43 ENSDART00000144440
wingless-type MMTV integration site family, member 6b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxj1a+foxj1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0090131 mesenchyme migration(GO:0090131)
3.1 9.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
2.4 7.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
2.1 8.5 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
1.9 5.7 GO:0000103 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.7 10.1 GO:0006004 fucose metabolic process(GO:0006004)
1.3 5.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
1.2 7.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.0 14.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.9 5.5 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.9 2.6 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.9 2.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.7 4.5 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.7 5.5 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.7 2.7 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.7 2.0 GO:1901295 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.7 2.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.7 4.6 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.6 3.2 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.6 3.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.6 2.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.6 4.0 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.6 2.8 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.5 3.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.5 26.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 5.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.5 6.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 1.4 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.4 2.2 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.4 4.9 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 7.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4 4.6 GO:0045453 bone resorption(GO:0045453)
0.4 1.2 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.4 1.2 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.4 3.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.4 3.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.4 1.9 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 1.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.4 1.1 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.4 2.5 GO:0061056 sclerotome development(GO:0061056)
0.3 1.4 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.3 5.0 GO:0043462 regulation of ATPase activity(GO:0043462)
0.3 2.0 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.3 4.6 GO:0051597 response to methylmercury(GO:0051597)
0.3 6.8 GO:0071456 cellular response to hypoxia(GO:0071456)
0.3 4.8 GO:0003417 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.3 3.8 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.3 1.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 4.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.3 2.8 GO:0072337 modified amino acid transport(GO:0072337)
0.3 0.8 GO:0051026 chiasma assembly(GO:0051026)
0.3 1.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.3 0.8 GO:0014857 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.3 4.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.3 11.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.3 3.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.3 2.8 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 6.9 GO:0007286 spermatid development(GO:0007286)
0.2 5.8 GO:0007634 optokinetic behavior(GO:0007634)
0.2 3.1 GO:0042694 muscle cell fate specification(GO:0042694)
0.2 1.7 GO:0046323 glucose import(GO:0046323)
0.2 1.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 8.0 GO:0030199 collagen fibril organization(GO:0030199)
0.2 4.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.8 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.2 0.6 GO:0030238 male sex determination(GO:0030238)
0.2 1.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 2.8 GO:0032094 response to food(GO:0032094)
0.2 2.9 GO:0031641 regulation of myelination(GO:0031641)
0.2 3.1 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.2 2.3 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.2 4.3 GO:0050795 regulation of behavior(GO:0050795)
0.2 1.7 GO:1901998 toxin transport(GO:1901998)
0.2 3.3 GO:0015693 magnesium ion transport(GO:0015693)
0.2 4.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 5.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 1.6 GO:0046686 response to cadmium ion(GO:0046686)
0.2 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.2 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.2 2.0 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.2 1.6 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.2 2.1 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 2.3 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.7 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 1.1 GO:0044211 CTP salvage(GO:0044211)
0.1 3.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 2.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444)
0.1 1.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 2.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 2.8 GO:0019835 cytolysis(GO:0019835)
0.1 3.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.6 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.1 0.5 GO:0090398 cellular senescence(GO:0090398)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 7.3 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.5 GO:0097009 energy homeostasis(GO:0097009)
0.1 1.6 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518) steroid hormone mediated signaling pathway(GO:0043401)
0.1 3.5 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 2.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 4.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 2.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.7 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.1 1.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.8 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 2.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 3.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 4.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.9 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 1.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.5 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.7 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.5 GO:0030901 midbrain development(GO:0030901)
0.0 1.5 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 2.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.7 GO:0008272 sulfate transport(GO:0008272)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.0 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 2.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.9 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 4.8 GO:0045597 positive regulation of cell differentiation(GO:0045597)
0.0 3.0 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 5.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.1 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 1.5 GO:0017148 negative regulation of translation(GO:0017148)
0.0 2.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 2.1 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.7 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.9 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 5.4 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 3.8 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.8 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 1.1 GO:0006260 DNA replication(GO:0006260)
0.0 1.2 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.6 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.7 GO:0006457 protein folding(GO:0006457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 14.1 GO:0042612 MHC class I protein complex(GO:0042612)
1.0 2.9 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.9 14.3 GO:0005869 dynactin complex(GO:0005869)
0.8 34.9 GO:0005861 troponin complex(GO:0005861)
0.6 1.8 GO:0034515 proteasome storage granule(GO:0034515)
0.6 3.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.5 2.0 GO:0016460 myosin II complex(GO:0016460)
0.5 6.3 GO:0000815 ESCRT III complex(GO:0000815)
0.4 1.6 GO:0017177 glucosidase II complex(GO:0017177)
0.4 2.3 GO:0070695 FHF complex(GO:0070695)
0.3 2.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 2.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 2.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 2.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.3 5.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 5.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 2.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 4.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 2.3 GO:0017119 Golgi transport complex(GO:0017119)
0.2 3.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 2.8 GO:0005579 membrane attack complex(GO:0005579)
0.2 3.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 6.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 6.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.9 GO:0022627 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.7 GO:0071797 LUBAC complex(GO:0071797)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.1 1.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 0.5 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 18.2 GO:0005667 transcription factor complex(GO:0005667)
0.1 8.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 8.8 GO:0005764 lysosome(GO:0005764)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 2.2 GO:0016605 PML body(GO:0016605)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.6 GO:0030496 midbody(GO:0030496)
0.1 3.1 GO:0005643 nuclear pore(GO:0005643)
0.1 2.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.6 GO:0005581 collagen trimer(GO:0005581)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 4.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 3.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 54.8 GO:0005576 extracellular region(GO:0005576)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.8 GO:0045495 pole plasm(GO:0045495)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.9 GO:0005938 cell cortex(GO:0005938)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.9 5.7 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.8 7.1 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
1.0 5.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.9 5.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.8 5.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 8.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.7 2.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.7 2.8 GO:0051380 norepinephrine binding(GO:0051380)
0.7 3.5 GO:0008097 5S rRNA binding(GO:0008097)
0.6 4.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6 4.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.5 1.6 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.5 2.0 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.5 1.4 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.4 2.7 GO:0015616 DNA translocase activity(GO:0015616)
0.4 1.2 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.4 10.5 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.4 2.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 1.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 1.0 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.3 11.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.3 4.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 3.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 2.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.3 4.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.6 GO:1903924 estradiol binding(GO:1903924)
0.2 2.3 GO:0035198 miRNA binding(GO:0035198)
0.2 1.4 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 1.5 GO:0001727 lipid kinase activity(GO:0001727)
0.2 2.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 10.5 GO:0008013 beta-catenin binding(GO:0008013)
0.2 3.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.2 2.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 3.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.1 GO:0070888 E-box binding(GO:0070888)
0.2 3.2 GO:0070411 I-SMAD binding(GO:0070411)
0.2 2.1 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 4.9 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 3.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 1.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 2.0 GO:0030515 snoRNA binding(GO:0030515)
0.1 12.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 1.9 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.5 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 2.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 3.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.5 GO:0008126 acetylesterase activity(GO:0008126)
0.1 15.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.1 4.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 4.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 3.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 6.1 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.7 GO:0019213 deacetylase activity(GO:0019213)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 25.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 2.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 11.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.2 GO:0043236 laminin binding(GO:0043236)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 3.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 4.4 GO:0008201 heparin binding(GO:0008201)
0.1 6.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 3.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.6 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.2 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 2.3 GO:0008134 transcription factor binding(GO:0008134)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.3 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 14.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.4 5.8 PID IL5 PATHWAY IL5-mediated signaling events
0.2 8.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 3.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 5.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 3.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 3.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 2.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.2 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 3.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 6.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.3 PID ATR PATHWAY ATR signaling pathway
0.1 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 8.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 6.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 14.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.7 8.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.7 4.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.5 4.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.5 4.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 2.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.3 7.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.3 5.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 7.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 1.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 3.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 3.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 11.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 5.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 1.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.1 1.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 3.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.4 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.1 0.6 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 4.0 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME G1 PHASE Genes involved in G1 Phase