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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxo3b+foxo6a+foxo6b

Z-value: 0.41

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Transcription factors associated with foxo3b+foxo6a+foxo6b

Gene Symbol Gene ID Gene Info
ENSDARG00000024619 forkhead box O6 b
ENSDARG00000042904 forkhead box O3b
ENSDARG00000100486 forkhead box O6 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo6adr11_v1_chr16_-_7362806_73628060.381.5e-04Click!
foxo6bdr11_v1_chr19_+_15571290_155712900.364.3e-04Click!
foxo3bdr11_v1_chr20_-_32332736_323327360.122.6e-01Click!

Activity profile of foxo3b+foxo6a+foxo6b motif

Sorted Z-values of foxo3b+foxo6a+foxo6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_38125657 4.81 ENSDART00000143433
cerebellin 12
chr7_-_65492048 3.29 ENSDART00000162381
dickkopf WNT signaling pathway inhibitor 3a
chr21_+_11468934 2.60 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr19_-_13286722 1.92 ENSDART00000168296
ENSDART00000158330
zinc finger protein, FOG family member 2b
chr16_-_29480335 1.86 ENSDART00000148930
leucine rich repeat and Ig domain containing 4b
chr24_+_32411753 1.86 ENSDART00000058530
neuronal differentiation 6a
chr13_+_36613359 1.81 ENSDART00000140598
si:ch211-67f24.7
chr11_+_41560792 1.81 ENSDART00000127292
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr6_+_58549080 1.80 ENSDART00000180117
stathmin-like 3
chr3_-_62380146 1.76 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr6_+_54221654 1.74 ENSDART00000128456
protein kinase C and casein kinase substrate in neurons 1b
chr1_+_10018466 1.74 ENSDART00000113551
tripartite motif containing 2b
chr16_+_34479064 1.67 ENSDART00000159965
si:ch211-255i3.4
chr14_-_4682114 1.65 ENSDART00000014454
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr19_+_8481802 1.65 ENSDART00000050217
ephrin-A1a
chr14_-_2221877 1.47 ENSDART00000106704
protocadherin 2 alpha b 1
chr19_-_19599372 1.46 ENSDART00000160002
ENSDART00000171664
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr18_-_40509006 1.46 ENSDART00000021372
cholinergic receptor, nicotinic, alpha 5
chr21_-_43949208 1.46 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr7_-_30174882 1.42 ENSDART00000110409
FERM domain containing 5
chr15_-_12319065 1.42 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr24_+_32472155 1.40 ENSDART00000098859
neuronal differentiation 6a
chr3_-_48716422 1.36 ENSDART00000164979
si:ch211-114m9.1
chr20_+_25911342 1.30 ENSDART00000146004
tau tubulin kinase 2b
chr7_+_30240791 1.29 ENSDART00000109243
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr5_+_28433215 1.29 ENSDART00000165072
ENSDART00000168005
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr10_-_21046917 1.25 ENSDART00000091004
protocadherin 1a
chr17_-_28198099 1.23 ENSDART00000156143
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr16_-_25400257 1.16 ENSDART00000040756
zgc:136493
chr9_-_785444 1.13 ENSDART00000012506
engrailed homeobox 1a
chr13_-_29420885 1.11 ENSDART00000024225
choline O-acetyltransferase a
chr12_+_28799988 1.07 ENSDART00000022724
pyridoxamine 5'-phosphate oxidase
chr3_+_43460696 1.07 ENSDART00000164581
galanin receptor 2b
chr3_+_62317990 1.07 ENSDART00000058719
zinc finger protein 1124
chr23_-_12158685 1.05 ENSDART00000135035
family with sequence similarity 217, member B
chr21_-_13123176 1.04 ENSDART00000144866
ENSDART00000024616
family with sequence similarity 219, member Aa
chr12_+_31713239 1.02 ENSDART00000122379
hyaluronan binding protein 2
chr23_-_36670369 1.01 ENSDART00000006881
zinc finger and BTB domain containing 39
chr14_+_34547554 1.01 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr6_-_41138854 1.00 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr5_-_12031174 1.00 ENSDART00000159896
cytosolic arginine sensor for mTORC1 subunit 1
chr11_+_23933016 0.96 ENSDART00000000486
contactin 2
chr23_+_31405497 0.95 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr7_-_36358735 0.92 ENSDART00000188392
fat mass and obesity associated
chr14_-_32893785 0.92 ENSDART00000169380
solute carrier family 25, member 43
chr5_+_38726854 0.91 ENSDART00000138484
ENSDART00000142867
si:dkey-58f10.7
chr7_-_36358303 0.89 ENSDART00000130028
fat mass and obesity associated
chr19_-_47323267 0.88 ENSDART00000190077

chr7_-_57949117 0.87 ENSDART00000138803
ankyrin 2b, neuronal
chr1_+_42874410 0.84 ENSDART00000153506
catenin (cadherin-associated protein), alpha 2
chr8_+_47897734 0.81 ENSDART00000140266
mitofusin 2
chr18_+_10689772 0.79 ENSDART00000126441
leptin a
chr1_+_31942961 0.77 ENSDART00000007522
anosmin 1a
chr2_+_10134345 0.75 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr24_-_6345965 0.75 ENSDART00000178287
zgc:174877
chr12_+_11352630 0.74 ENSDART00000129495
si:rp71-19m20.1
chr4_-_71110826 0.74 ENSDART00000167431
si:dkeyp-80d11.1
chr2_-_43850897 0.73 ENSDART00000005449
zinc finger E-box binding homeobox 1a
chr14_-_46238186 0.73 ENSDART00000173245
si:ch211-113d11.6
chr9_-_16877456 0.73 ENSDART00000161105
ENSDART00000160869
F-box and leucine-rich repeat protein 3a
chr16_+_46000956 0.73 ENSDART00000101753
ENSDART00000162393
myotubularin related protein 11
chr9_+_38624478 0.71 ENSDART00000077389
ENSDART00000114728
zinc finger protein 148
chr3_-_26341959 0.69 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
chr22_-_21676364 0.67 ENSDART00000183668
transducin like enhancer of split 2b
chr6_+_28124393 0.63 ENSDART00000089195
G protein-coupled receptor 17
chr15_-_8177919 0.61 ENSDART00000101463
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr19_-_23470709 0.61 ENSDART00000138884
Pim proto-oncogene, serine/threonine kinase, related 80
chr9_-_3834686 0.59 ENSDART00000141492
myosin IIIB
chr25_-_16832705 0.59 ENSDART00000171336
ENSDART00000189396
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr21_-_37973081 0.58 ENSDART00000136569
ripply transcriptional repressor 1
chr2_-_7131657 0.57 ENSDART00000175565
ENSDART00000092116
exostosin-like glycosyltransferase 2
chr5_+_57320113 0.57 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr6_+_18531932 0.57 ENSDART00000165271
SUZ12 polycomb repressive complex 2b subunit
chr22_-_34995333 0.56 ENSDART00000110900
Kv channel interacting protein 2
chr22_+_2524615 0.56 ENSDART00000134277
zinc finger protein 1003
chr9_-_3149896 0.56 ENSDART00000020861
pyruvate dehydrogenase kinase, isozyme 1
chr18_-_20560007 0.56 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
chr22_+_2533514 0.56 ENSDART00000147967
si:ch73-92e7.4
chr17_-_50436199 0.56 ENSDART00000156494
si:ch211-235i11.6
chr24_-_6345647 0.55 ENSDART00000108994
zgc:174877
chr7_+_61906903 0.53 ENSDART00000108540
tudor domain containing 7 b
chr12_+_46582168 0.53 ENSDART00000189402
Usher syndrome 1Gb (autosomal recessive)
chr16_-_21181128 0.52 ENSDART00000133403
phosphodiesterase 11a, like
chr13_-_8601184 0.52 ENSDART00000045086
protein kinase C, epsilon b
chr22_+_7486867 0.52 ENSDART00000034586
zgc:112302
chr3_-_31078348 0.52 ENSDART00000055360
elongin B
chr5_-_26118855 0.51 ENSDART00000009028
elastase 3 like
chr21_-_29110607 0.51 ENSDART00000181595
hepatitis A virus cellular receptor 1
chr21_+_22828500 0.51 ENSDART00000151109
si:rp71-1p14.7
chr18_+_48943875 0.50 ENSDART00000076803

chr14_-_17305849 0.50 ENSDART00000160971
janus kinase and microtubule interacting protein 1
chr1_-_10347198 0.49 ENSDART00000109141
ENSDART00000152565
si:ch211-243g6.3
chr10_-_25570647 0.48 ENSDART00000134215
glutamate receptor, ionotropic, kainate 1a
chr6_+_15762647 0.48 ENSDART00000127133
ENSDART00000128939
IQ motif containing with AAA domain 1
chr21_+_17301790 0.48 ENSDART00000145057
TSC complex subunit 1b
chr6_-_18531760 0.48 ENSDART00000167167
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr22_+_7462997 0.46 ENSDART00000106082
zgc:112368
chr5_+_29652198 0.46 ENSDART00000184083
TSC complex subunit 1a
chr19_-_21766461 0.45 ENSDART00000104279
zinc finger protein 516
chr6_+_55819038 0.45 ENSDART00000108786
si:ch211-81n22.1
chr14_-_17305657 0.44 ENSDART00000168853
janus kinase and microtubule interacting protein 1
chr2_-_44199722 0.43 ENSDART00000140633
ENSDART00000145728
succinate dehydrogenase complex, subunit C, integral membrane protein
chr17_-_50454957 0.43 ENSDART00000171616
ENSDART00000075195
si:ch211-235i11.7
chr6_-_46560207 0.42 ENSDART00000187607
potassium voltage-gated channel, Shab-related subfamily, member 1
chr22_+_7480465 0.42 ENSDART00000034545
zgc:92745
chr13_-_32626247 0.42 ENSDART00000100663
WD repeat domain 35
chr6_-_51386656 0.42 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
protein tyrosine phosphatase, receptor type, t
chr6_+_10077756 0.42 ENSDART00000150982
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate b
chr11_+_25044082 0.41 ENSDART00000123263
PHD finger protein 20, a
chr18_+_41527877 0.41 ENSDART00000146972
selenoprotein T, 1b
chr5_-_31035198 0.40 ENSDART00000086534
cytochrome b5 domain containing 2
chr1_-_45752010 0.40 ENSDART00000101410
si:ch211-214c7.5
chr14_-_6402769 0.40 ENSDART00000121552
solute carrier family 44 (choline transporter), member 1b
chr7_+_32021669 0.39 ENSDART00000173976
methyltransferase like 15
chr4_-_64123545 0.39 ENSDART00000170040

chr16_-_31351419 0.39 ENSDART00000178298
ENSDART00000018091
maestro heat-like repeat family member 1
chr20_+_22067337 0.38 ENSDART00000152636
clock circadian regulator a
chr19_+_19600297 0.38 ENSDART00000160134
ENSDART00000183493
3-hydroxyisobutyrate dehydrogenase a
chr4_-_77377596 0.37 ENSDART00000186068
solute carrier organic anion transporter family, member 1E1
chr23_+_17878969 0.36 ENSDART00000154934
ENSDART00000154140
ENSDART00000156331
si:ch73-390p7.2
chr5_-_30145939 0.36 ENSDART00000086795
zinc finger and BTB domain containing 44
chr25_+_28158352 0.35 ENSDART00000151854
Ca++-dependent secretion activator 2
chr2_-_31540922 0.33 ENSDART00000056686
mannose receptor, C type 1b
chr4_-_12781182 0.33 ENSDART00000058020
helicase (DNA) B
chr1_+_6357059 0.32 ENSDART00000166620
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2b
chr7_-_19966406 0.32 ENSDART00000010932
sorting nexin 15
chr8_-_16464453 0.32 ENSDART00000098691
ring finger protein 11b
chr8_-_36125849 0.31 ENSDART00000159581

chr4_+_75458537 0.31 ENSDART00000166278
si:ch211-266c8.1
chr8_-_14179798 0.31 ENSDART00000040645
ENSDART00000146749
ras homolog gene family, member Aa
chr1_+_19708508 0.31 ENSDART00000054581
ENSDART00000131206
membrane-associated ring finger (C3HC4) 1
chr16_-_8663493 0.30 ENSDART00000014944
ENSDART00000181533
ENSDART00000182721
ENSDART00000162988
cordon-bleu WH2 repeat protein
chr5_-_25733745 0.30 ENSDART00000051566
zgc:101016
chr6_+_52859495 0.29 ENSDART00000103135
odorant receptor, family H, subfamily 134, member 1
chr2_-_43850637 0.29 ENSDART00000136077
zinc finger E-box binding homeobox 1a
chr17_-_5610514 0.29 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr17_-_50472864 0.29 ENSDART00000161066
ENSDART00000156963
si:ch211-235i11.3
chr4_+_20536120 0.28 ENSDART00000125685
zmp:0000000650
chr18_-_46208581 0.28 ENSDART00000141278
si:ch211-14c7.2
chr14_-_17306261 0.28 ENSDART00000191747
janus kinase and microtubule interacting protein 1
chr2_+_24317465 0.27 ENSDART00000139339
ENSDART00000136284
mitochondrial ribosomal protein L34
chr1_+_5576151 0.27 ENSDART00000109756
carboxypeptidase O
chr12_+_17603528 0.27 ENSDART00000111565
PMS1 homolog 2, mismatch repair system component
chr10_+_38526496 0.26 ENSDART00000144329
alkaline ceramidase 3
chr2_-_24317240 0.26 ENSDART00000078975
tRNA selenocysteine 1 associated protein 1b
chr22_-_10440688 0.26 ENSDART00000111962
nucleolar protein 8
chr22_-_5958066 0.26 ENSDART00000145821
si:rp71-36a1.3
chr24_+_19591893 0.26 ENSDART00000152026
solute carrier organic anion transporter family member 5A1a
chr22_-_23590069 0.25 ENSDART00000172067
coagulation factor XIII, B polypeptide
chr22_-_17499513 0.25 ENSDART00000105460
si:ch211-197g15.6
chr2_+_42318012 0.24 ENSDART00000138137
finTRIM family, member 8
chr1_+_8314826 0.24 ENSDART00000160440
calcium channel, voltage-dependent, T type, alpha 1H subunit b
chr17_+_8175998 0.23 ENSDART00000131200
myc target 1b
chr6_+_53429228 0.23 ENSDART00000165067
abhydrolase domain containing 14B
chr23_+_4777612 0.23 ENSDART00000135933
vestigial-like family member 4a
chr6_+_30091811 0.21 ENSDART00000088403
melanotransferrin
chr15_-_44465679 0.21 ENSDART00000054605
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr3_+_52684556 0.21 ENSDART00000139037
6-phosphogluconolactonase
chr1_+_6646529 0.20 ENSDART00000144641
ENSDART00000103701
ENSDART00000138919
ubiquitin-conjugating enzyme E2F (putative)
chr3_-_46115232 0.20 ENSDART00000074537
shisa family member 9b
chr4_+_42604252 0.19 ENSDART00000184850

chr21_+_17541634 0.18 ENSDART00000191700
ENSDART00000163238
stomatin
chr20_-_7069612 0.18 ENSDART00000040793
sirtuin 5
chr13_-_31377299 0.17 ENSDART00000026692
ubiquitin domain containing 1a
chr7_-_13362590 0.17 ENSDART00000091616
succinate dehydrogenase complex assembly factor 2
chr8_-_53044089 0.16 ENSDART00000135982
nuclear receptor subfamily 6, group A, member 1a
chr17_-_2834764 0.16 ENSDART00000024027
bradykinin receptor B1
chr3_+_34180835 0.16 ENSDART00000055252
translocase of inner mitochondrial membrane 29
chr10_+_25369254 0.16 ENSDART00000164375
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr21_-_17037907 0.15 ENSDART00000101263
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr18_-_3103827 0.15 ENSDART00000165048
adipogenesis associated, Mth938 domain containing
chr15_+_791220 0.15 ENSDART00000136137
si:dkey-7i4.1
chr6_+_3516926 0.15 ENSDART00000151607
fatty acid amide hydrolase
chr11_-_23697217 0.15 ENSDART00000124810
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr2_+_23130389 0.15 ENSDART00000142834
si:dkey-218h11.6
chr18_+_33100606 0.14 ENSDART00000003907
si:ch211-229c8.13
chr6_+_46259950 0.14 ENSDART00000032326
zgc:162324
chr15_-_31406093 0.14 ENSDART00000123444
odorant receptor, family D, subfamily 111, member 8
chr25_+_4855549 0.13 ENSDART00000163839
adaptor-related protein complex 4, epsilon 1 subunit
chr2_-_24907741 0.13 ENSDART00000155013
si:dkey-149i17.11
chr13_-_25842074 0.13 ENSDART00000015154
poly(A) polymerase gamma
chr15_-_8191992 0.11 ENSDART00000155381
ENSDART00000190714
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr22_-_34715364 0.11 ENSDART00000189348

chr5_+_56119975 0.11 ENSDART00000083137
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr16_+_46410520 0.11 ENSDART00000131072
rapunzel 2
chr12_-_28799642 0.09 ENSDART00000066303
mitochondrial ribosomal protein L10
chr4_-_53047883 0.09 ENSDART00000157496
si:dkey-201g16.5
chr22_+_18319230 0.08 ENSDART00000184747
ENSDART00000184649
GATA zinc finger domain containing 2Ab
chr5_-_68795063 0.08 ENSDART00000016307
hairy-related 1
chr5_-_51998708 0.08 ENSDART00000097194
serine incorporator 5
chr5_+_29652513 0.08 ENSDART00000035400
TSC complex subunit 1a
chr18_-_44526940 0.07 ENSDART00000077125
amyloid beta (A4) precursor-like protein 2
chr23_+_17417539 0.07 ENSDART00000182605

chr2_-_51388214 0.07 ENSDART00000163838
si:dkeyp-104b3.18
chr18_-_10995410 0.06 ENSDART00000136751
tetraspanin 33b
chr8_-_53044300 0.06 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr20_+_33994580 0.05 ENSDART00000061729
si:dkey-97o5.1
chr11_+_45422206 0.05 ENSDART00000182548
HRAS-like suppressor
chr7_-_30932094 0.05 ENSDART00000057677
telomere repeat binding bouquet formation protein 2
chr3_+_33918510 0.05 ENSDART00000055248
alkB homolog 7

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3b+foxo6a+foxo6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0042245 RNA repair(GO:0042245)
0.4 1.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.4 1.1 GO:0042822 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 1.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.3 1.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 1.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 1.0 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.8 GO:0098900 regulation of action potential(GO:0098900)
0.1 2.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 1.5 GO:0035094 response to nicotine(GO:0035094)
0.1 0.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.8 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 2.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.5 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 1.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.7 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.2 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 1.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 1.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 3.0 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.4 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 1.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 3.3 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.0 GO:0044821 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.7 GO:0003146 heart jogging(GO:0003146)
0.0 0.6 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 1.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0021591 ventricular system development(GO:0021591)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 0.4 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 3.3 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 1.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.0 GO:0032044 DSIF complex(GO:0032044)
0.0 9.4 GO:0043005 neuron projection(GO:0043005)
0.0 0.3 GO:0098978 glutamatergic synapse(GO:0098978)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0039706 co-receptor binding(GO:0039706)
0.5 1.8 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.4 1.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.0 GO:0034618 arginine binding(GO:0034618)
0.3 1.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 2.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.7 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.1 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 1.6 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0009931 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 1.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 1.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels