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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for foxo4

Z-value: 1.14

Motif logo

Transcription factors associated with foxo4

Gene Symbol Gene ID Gene Info
ENSDARG00000055792 forkhead box O4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo4dr11_v1_chr14_+_30910114_309101140.572.0e-09Click!

Activity profile of foxo4 motif

Sorted Z-values of foxo4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_36378494 13.31 ENSDART00000058503
glycoprotein M6Aa
chr13_+_22675802 10.43 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr7_+_22637515 8.78 ENSDART00000158698
si:dkey-112a7.5
chr5_+_37837245 8.43 ENSDART00000171617
ependymin
chr12_+_25640480 7.42 ENSDART00000105608
protein kinase C, epsilon a
chr6_-_30839763 7.05 ENSDART00000154228
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr5_+_28271412 7.01 ENSDART00000031727
vesicle-associated membrane protein 8 (endobrevin)
chr20_-_39273987 6.92 ENSDART00000127173
clusterin
chr14_-_34044369 6.77 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr4_-_4256300 6.66 ENSDART00000103319
ENSDART00000150279
CD9 molecule b
chr24_+_17007407 6.43 ENSDART00000110652
zinc finger protein, X-linked
chr18_-_17485419 6.03 ENSDART00000018764
forkhead box L1
chr6_+_48618512 5.77 ENSDART00000111190
si:dkey-238f9.1
chr11_+_18873619 5.73 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr12_+_19188542 5.73 ENSDART00000134726
ENSDART00000148011
ENSDART00000109541
chibby homolog 1 (Drosophila)
chr12_-_11457625 5.70 ENSDART00000012318
HtrA serine peptidase 1b
chr20_-_39273505 5.69 ENSDART00000153114
clusterin
chr7_+_60551133 5.54 ENSDART00000148038
leucine rich repeat and fibronectin type III domain containing 4b
chr11_+_25112269 5.36 ENSDART00000147546
ndrg family member 3a
chr18_+_17428506 5.12 ENSDART00000100223
zgc:91860
chr9_+_9502610 5.03 ENSDART00000061525
ENSDART00000125174
nuclear receptor subfamily 1, group I, member 2
chr19_-_5103141 5.02 ENSDART00000150952
triosephosphate isomerase 1a
chr10_+_33744098 4.92 ENSDART00000147775
relaxin/insulin-like family peptide receptor 2a
chr14_-_7885707 4.87 ENSDART00000029981
protein phosphatase 3, catalytic subunit, beta isozyme
chr7_-_30082931 4.69 ENSDART00000075600
tetraspanin 3b
chr1_-_37383539 4.69 ENSDART00000127579
secretory calcium-binding phosphoprotein 1
chr16_-_43025885 4.68 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr13_-_25842074 4.64 ENSDART00000015154
poly(A) polymerase gamma
chr13_+_22280983 4.59 ENSDART00000173258
ENSDART00000173379
ubiquitin specific peptidase 54a
chr22_-_29689981 4.58 ENSDART00000009223
programmed cell death 4b
chr22_+_4707663 4.58 ENSDART00000042194
ceramide synthase 4a
chr19_-_5103313 4.57 ENSDART00000037007
triosephosphate isomerase 1a
chr6_+_36942966 4.35 ENSDART00000028895
neuronal growth regulator 1
chr9_+_38163876 4.34 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr6_-_40657653 4.34 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr12_+_27213733 4.33 ENSDART00000133048
neighbor of brca1 gene 1a
chr23_-_36449111 4.28 ENSDART00000110478
zgc:174906
chr16_-_15988320 4.27 ENSDART00000160883

chr9_+_3388099 4.23 ENSDART00000019910
distal-less homeobox 1a
chr3_+_32403758 4.23 ENSDART00000156982
si:ch211-195b15.8
chr22_-_29689485 4.23 ENSDART00000182173
programmed cell death 4b
chr21_+_25071805 4.18 ENSDART00000078651
DIX domain containing 1b
chr16_+_28578352 4.18 ENSDART00000149306
N-myristoyltransferase 2
chr21_+_33459524 4.11 ENSDART00000053205
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr1_+_16127825 4.03 ENSDART00000122503
tumor suppressor candidate 3
chr8_+_23639124 4.01 ENSDART00000083108
5'-nucleotidase domain containing 2
chr20_-_20610812 3.93 ENSDART00000181870
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr14_-_32824380 3.92 ENSDART00000172791
ENSDART00000105745
inositol polyphosphate phosphatase-like 1b
chr14_+_29769336 3.86 ENSDART00000105898
si:dkey-34l15.1
chr13_+_27316934 3.84 ENSDART00000164533
eukaryotic translation elongation factor 1 alpha 1a
chr5_-_25583125 3.83 ENSDART00000031665
ENSDART00000145353
annexin A1a
chr10_+_39084354 3.80 ENSDART00000158245
si:ch73-1a9.3
chr13_+_27316632 3.79 ENSDART00000016121
eukaryotic translation elongation factor 1 alpha 1a
chr17_-_15546862 3.76 ENSDART00000091021
collagen, type X, alpha 1a
chr9_-_24209083 3.76 ENSDART00000134599
zgc:153521
chr20_+_23238833 3.67 ENSDART00000074167
OCIA domain containing 2
chr18_+_6857071 3.65 ENSDART00000018735
ENSDART00000181969
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr6_-_13022166 3.65 ENSDART00000157139
transmembrane BAX inhibitor motif containing 1a
chr13_+_1100197 3.62 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
chr2_+_11205795 3.62 ENSDART00000019078
LIM homeobox 8a
chr1_+_45969240 3.62 ENSDART00000042086
Rho guanine nucleotide exchange factor (GEF) 7b
chr12_-_19346678 3.54 ENSDART00000044860
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr18_-_20560007 3.53 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
chr12_+_16967715 3.53 ENSDART00000138174
solute carrier family 16, member 12b
chr6_-_40744720 3.48 ENSDART00000154916
ENSDART00000186922
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr12_+_25775734 3.46 ENSDART00000024415
ENSDART00000149198
endothelial PAS domain protein 1a
chr15_+_21252532 3.45 ENSDART00000162619
ENSDART00000019636
ENSDART00000144901
ENSDART00000138676
ENSDART00000133821
ENSDART00000146967
ENSDART00000143990
ENSDART00000142070
ENSDART00000132373
upstream transcription factor 1
chr3_-_28258462 3.45 ENSDART00000191573
RNA binding fox-1 homolog 1
chr2_+_49572059 3.45 ENSDART00000108861
semaphorin 4e
chr21_-_22435957 3.44 ENSDART00000137959
interleukin 7 receptor
chr5_+_34407763 3.39 ENSDART00000188849
ENSDART00000145127
laminin, gamma 3
chr25_-_11088839 3.33 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr21_+_45757317 3.29 ENSDART00000163152
H2A histone family, member Y
chr25_+_19149241 3.28 ENSDART00000184982
ENSDART00000067324
milk fat globule-EGF factor 8 protein b
chr2_-_11662851 3.27 ENSDART00000145108
zgc:110130
chr5_-_51998708 3.26 ENSDART00000097194
serine incorporator 5
chr15_+_26933196 3.20 ENSDART00000023842
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr19_-_34063567 3.19 ENSDART00000157815
ENSDART00000183907
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr11_-_30634286 3.17 ENSDART00000191019
zgc:153665
chr18_-_1228688 3.15 ENSDART00000064403
neuroplastin b
chr3_+_15817644 3.11 ENSDART00000055787
zgc:110779
chr12_-_28848015 3.11 ENSDART00000153200
si:ch211-194k22.8
chr5_-_66749535 3.10 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr4_+_18843015 3.08 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
BCL2 interacting killer
chr14_+_26715626 3.08 ENSDART00000078557
polymerase (RNA) II (DNA directed) polypeptide G-like
chr5_-_46329880 3.03 ENSDART00000156577
si:ch211-130m23.5
chr11_+_16153207 3.02 ENSDART00000192356
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr10_+_26834985 2.99 ENSDART00000147518
family with sequence similarity 89, member B
chr12_-_28537615 2.95 ENSDART00000067762
si:ch211-94l19.4
chr16_+_10318893 2.94 ENSDART00000055380
tubulin, beta 5
chr7_+_22688781 2.91 ENSDART00000173509
UDP glucuronosyltransferase 5 family, polypeptide G1
chr20_-_40119872 2.90 ENSDART00000191569
sodium/potassium transporting ATPase interacting 2
chr12_+_8822717 2.89 ENSDART00000021628
receptor accessory protein 3b
chr22_+_30335936 2.84 ENSDART00000059923
max interactor 1, dimerization protein
chr19_+_46222428 2.83 ENSDART00000183984
vacuolar protein sorting 28 (yeast)
chr5_+_22579975 2.82 ENSDART00000080877
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr2_-_12243213 2.79 ENSDART00000113081
G protein-coupled receptor 158b
chr14_-_32876280 2.78 ENSDART00000173168
si:rp71-46j2.7
chr20_-_19590378 2.78 ENSDART00000152588
brain and acute leukemia, cytoplasmic b
chr1_-_30689004 2.77 ENSDART00000018827
dachshund c
chr17_+_44030692 2.77 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr9_+_17971935 2.76 ENSDART00000149736
A kinase (PRKA) anchor protein 11
chr3_-_31254379 2.76 ENSDART00000189376
actinoporin-like protein
chr1_-_37383741 2.75 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
secretory calcium-binding phosphoprotein 1
chr20_-_31497300 2.72 ENSDART00000046841
SAM and SH3 domain containing 1a
chr22_-_3914162 2.69 ENSDART00000187174
ENSDART00000190612
ENSDART00000187928
ENSDART00000057224
ENSDART00000184758
major histocompatibility complex class I UMA
chr3_-_45298487 2.67 ENSDART00000102245
3-phosphoinositide dependent protein kinase 1a
chr16_+_10413551 2.66 ENSDART00000032877
ENSDART00000172827
INO80 complex subunit E
chr13_+_30951155 2.63 ENSDART00000057469
ENSDART00000162254
V-set and transmembrane domain containing 4a
chr11_-_36001495 2.63 ENSDART00000190330
inositol 1,4,5-trisphosphate receptor, type 1b
chr11_+_16152316 2.60 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr14_-_48939560 2.58 ENSDART00000021736
short coiled-coil protein b
chr6_-_8244474 2.56 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr5_+_37504309 2.56 ENSDART00000165465
si:ch1073-224n8.1
chr5_-_45894802 2.55 ENSDART00000097648
cytokine receptor family member b6
chr17_+_38295847 2.54 ENSDART00000008532
MAP3K12 binding inhibitory protein 1
chr3_+_10152092 2.51 ENSDART00000066053
chromobox homolog 2 (Drosophila Pc class)
chr18_+_41561285 2.50 ENSDART00000169621
bromodomain adjacent to zinc finger domain, 1B
chr11_-_16152400 2.49 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr17_+_24718272 2.48 ENSDART00000007271
mitochondrial fission regulator 1-like
chr14_+_26439227 2.48 ENSDART00000054183
G protein-coupled receptor 137
chr19_+_46222918 2.48 ENSDART00000158703
vacuolar protein sorting 28 (yeast)
chr3_+_31621774 2.47 ENSDART00000076636
frizzled class receptor 2
chr24_-_25004553 2.47 ENSDART00000080997
ENSDART00000136860
zinc finger, DHHC-type containing 20b
chr25_-_25142387 2.47 ENSDART00000031814
tumor susceptibility 101a
chr3_-_25369557 2.46 ENSDART00000055491
SMAD specific E3 ubiquitin protein ligase 2
chr23_+_31596441 2.45 ENSDART00000053534
TBP-like 1
chr12_-_33314894 2.43 ENSDART00000152908
C1q and TNF related 1
chr14_+_33427837 2.43 ENSDART00000105687
zinc finger and BTB domain containing 33
chr20_-_39367895 2.43 ENSDART00000136476
ENSDART00000021788
ENSDART00000180784
PDZ binding kinase
chr10_+_33754967 2.42 ENSDART00000153442
relaxin/insulin-like family peptide receptor 2a
chr2_-_30200206 2.40 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr10_-_36633882 2.38 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr7_-_46782264 2.38 ENSDART00000166565
teashirt zinc finger homeobox 3b
chr3_+_27798094 2.37 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr22_+_3914318 2.37 ENSDART00000188774
ENSDART00000082034
Danio rerio major histocompatibility complex class I ULA (mhc1ula), mRNA.
chr13_-_4333181 2.36 ENSDART00000122406
zinc finger protein 318
chr3_-_26191960 2.35 ENSDART00000113843
yippee-like 3
chr11_+_11120532 2.34 ENSDART00000026135
ENSDART00000189872
lymphocyte antigen 75
chr7_+_56472585 2.33 ENSDART00000135259
ENSDART00000073596
increased sodium tolerance 1 homolog (yeast)
chr19_-_32600823 2.33 ENSDART00000134149
ENSDART00000187858
zgc:91944
chr4_+_9612574 2.32 ENSDART00000150336
ENSDART00000041289
ENSDART00000150828
transmembrane protein 243, mitochondrial b
chr16_+_6944564 2.32 ENSDART00000104252
ELL associated factor 1
chr20_+_25552057 2.31 ENSDART00000102913
cytochrome P450, family 2, subfamily V, polypeptide 1
chr15_+_37589698 2.30 ENSDART00000076066
ENSDART00000153894
ENSDART00000156298
lin-37 DREAM MuvB core complex component
chr14_-_33177935 2.30 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr18_+_16749091 2.28 ENSDART00000061265
ring finger protein 141
chr17_+_15388479 2.24 ENSDART00000052439
si:ch211-266g18.6
chr5_-_56924747 2.23 ENSDART00000014028
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr6_-_59505589 2.23 ENSDART00000170685
GLI family zinc finger 1
chr3_+_19685873 2.23 ENSDART00000006490
tousled-like kinase 2
chr24_-_6678640 2.19 ENSDART00000042478
enkurin, TRPC channel interacting protein
chr19_+_10396042 2.18 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr3_+_52999962 2.18 ENSDART00000104683
pre-B-cell leukemia transcription factor 4
chr3_-_60711127 2.17 ENSDART00000184119
UBA-like domain containing 2
chr23_-_10723009 2.17 ENSDART00000189721
forkhead box P1a
chr11_-_21586157 2.16 ENSDART00000190095
SLIT-ROBO Rho GTPase activating protein 2
chr19_+_40115977 2.16 ENSDART00000139802
si:ch211-173p18.3
chr9_+_17348745 2.14 ENSDART00000147488
SLAIN motif family, member 1a
chr3_-_16039619 2.13 ENSDART00000143324
splA/ryanodine receptor domain and SOCS box containing 3a
chr14_+_41406321 2.12 ENSDART00000111480
BCL6 corepressor-like 1
chr25_+_28823952 2.12 ENSDART00000067072
nuclear transcription factor Y, beta b
chr8_-_25716074 2.11 ENSDART00000007482
testis specific protein, Y-linked
chr9_-_13355071 2.10 ENSDART00000084055
frizzled class receptor 7a
chr7_+_47287307 2.09 ENSDART00000114669
dpy-19 like C-mannosyltransferase 3
chr3_-_15496551 2.08 ENSDART00000124063
ENSDART00000007726
SAGA complex associated factor 29
chr3_-_15679107 2.04 ENSDART00000080441
zgc:66443
chr11_+_6819050 2.03 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr9_+_41459759 2.02 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr11_-_34577034 2.01 ENSDART00000133302
ENSDART00000184367
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr21_-_42202792 2.01 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr18_+_1703984 2.00 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr11_-_25733910 1.99 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr13_+_9368621 1.98 ENSDART00000109126
Alstrom syndrome protein 1
chr19_+_20177887 1.95 ENSDART00000008595
transformer 2 alpha homolog
chr17_-_50010121 1.95 ENSDART00000122747
transmembrane protein 30Aa
chr17_+_24111392 1.95 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
EH domain binding protein 1
chr4_-_14207471 1.93 ENSDART00000015134
twinfilin actin-binding protein 1b
chr6_-_32045951 1.92 ENSDART00000016629
ENSDART00000139055
EF-hand calcium binding domain 7
chr17_+_41992054 1.90 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr10_+_22890791 1.90 ENSDART00000176011
arrestin, beta 2a
chr6_-_53334259 1.90 ENSDART00000172465
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr13_-_22903246 1.89 ENSDART00000089133
RUN and FYVE domain containing 2
chr23_-_17450746 1.89 ENSDART00000145399
ENSDART00000136457
ENSDART00000133125
ENSDART00000145719
ENSDART00000147524
ENSDART00000005366
ENSDART00000104680
tumor protein D52-like 2b
chr1_+_25801648 1.87 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr6_-_40922971 1.86 ENSDART00000155363
SFI1 centrin binding protein
chr6_-_42418225 1.86 ENSDART00000002501
inositol hexakisphosphate kinase 2a
chr18_-_15911394 1.86 ENSDART00000091339
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr3_-_15496295 1.85 ENSDART00000144369
SAGA complex associated factor 29
chr12_-_29624638 1.84 ENSDART00000126744
neuregulin 3b
chr5_-_20446082 1.84 ENSDART00000051607
si:ch211-191d15.2
chr15_+_46313082 1.84 ENSDART00000153830
si:ch1073-190k2.1
chr14_-_15155384 1.83 ENSDART00000172666
UV-stimulated scaffold protein A
chr7_+_60359347 1.82 ENSDART00000145201
ENSDART00000039827
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr21_-_27273147 1.82 ENSDART00000143239
MAP/microtubule affinity-regulating kinase 2a
chr9_+_32358514 1.81 ENSDART00000144608
phospholipase C like 1
chr11_-_183328 1.80 ENSDART00000168562
advillin
chr13_-_43599898 1.79 ENSDART00000084416
ENSDART00000145705
actin binding LIM protein 1a
chr2_+_16696052 1.78 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr1_-_9277986 1.77 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubinuclein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.4 4.1 GO:0010934 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
1.2 3.6 GO:0071896 protein localization to adherens junction(GO:0071896)
1.2 7.0 GO:0070254 mucus secretion(GO:0070254)
0.7 2.2 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.7 4.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.7 2.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.7 3.4 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.7 2.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.6 3.8 GO:0002828 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) regulation of type 2 immune response(GO:0002828) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.6 5.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.6 7.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.6 2.8 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.5 3.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.5 1.9 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.5 1.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.5 1.4 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.5 1.9 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.5 2.8 GO:0051818 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.5 6.8 GO:0001964 startle response(GO:0001964)
0.4 1.3 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.4 2.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.4 2.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.4 2.9 GO:0045475 locomotor rhythm(GO:0045475)
0.4 2.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.4 1.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.4 2.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.4 1.2 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.4 1.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.4 1.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.4 1.5 GO:0061010 gall bladder development(GO:0061010)
0.4 2.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 2.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.3 12.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.3 2.6 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 4.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.3 2.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 4.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 8.8 GO:0003171 atrioventricular valve development(GO:0003171)
0.3 1.1 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.3 0.8 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.3 2.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.3 2.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 1.3 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.3 1.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 1.5 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.3 3.5 GO:0014812 muscle cell migration(GO:0014812)
0.2 3.5 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.2 4.0 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.7 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.2 0.9 GO:0061113 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.2 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.2 7.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 2.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 4.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 1.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.2 0.6 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 1.8 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.2 0.8 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 12.6 GO:1901214 regulation of neuron death(GO:1901214)
0.2 1.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.2 0.8 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.2 0.6 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 3.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.2 3.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.2 4.6 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.2 1.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.2 9.9 GO:0007338 single fertilization(GO:0007338)
0.2 3.9 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 0.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 1.5 GO:0061056 sclerotome development(GO:0061056)
0.2 1.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 5.0 GO:0009636 response to toxic substance(GO:0009636)
0.1 3.6 GO:0021884 forebrain neuron development(GO:0021884)
0.1 2.0 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 6.0 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.1 4.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 2.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 7.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 5.2 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.1 1.7 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.5 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 1.1 GO:0045453 bone resorption(GO:0045453)
0.1 0.5 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling(GO:0098917) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 7.6 GO:0006414 translational elongation(GO:0006414)
0.1 2.3 GO:0007032 endosome organization(GO:0007032)
0.1 2.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.4 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 3.3 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.1 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 3.1 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.1 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 1.4 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.1 1.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.0 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 6.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 2.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.6 GO:0090398 cellular senescence(GO:0090398)
0.1 1.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.6 GO:0003139 secondary heart field specification(GO:0003139)
0.1 3.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.3 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 1.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 8.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 1.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 2.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.7 GO:0045824 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.1 0.2 GO:0036316 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 3.2 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 2.9 GO:0030901 midbrain development(GO:0030901)
0.1 11.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 0.4 GO:0000423 macromitophagy(GO:0000423)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 3.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 1.0 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 3.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.5 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.3 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 2.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.5 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 2.7 GO:0016573 histone acetylation(GO:0016573)
0.0 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 1.6 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 1.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 3.1 GO:0031101 fin regeneration(GO:0031101)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.0 GO:0010821 regulation of mitochondrion organization(GO:0010821)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 2.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 1.3 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.5 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 3.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.0 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.5 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.4 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 1.8 GO:0006906 vesicle fusion(GO:0006906) organelle membrane fusion(GO:0090174)
0.0 1.6 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 1.0 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 1.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 5.3 GO:0006897 endocytosis(GO:0006897)
0.0 1.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.6 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.7 GO:0071599 otic vesicle development(GO:0071599)
0.0 1.9 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0007051 spindle organization(GO:0007051)
0.0 5.2 GO:0045892 negative regulation of transcription, DNA-templated(GO:0045892)
0.0 7.0 GO:0031175 neuron projection development(GO:0031175)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0005828 kinetochore microtubule(GO:0005828)
1.3 12.6 GO:0042583 chromaffin granule(GO:0042583)
1.1 13.3 GO:0044295 axonal growth cone(GO:0044295)
1.1 9.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.9 2.8 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.8 4.9 GO:0005955 calcineurin complex(GO:0005955)
0.8 2.4 GO:0031213 RSF complex(GO:0031213)
0.5 4.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 2.0 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.5 2.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.4 3.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 6.8 GO:0031209 SCAR complex(GO:0031209)
0.4 3.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 1.3 GO:0017177 glucosidase II complex(GO:0017177)
0.3 5.3 GO:0000813 ESCRT I complex(GO:0000813)
0.3 4.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 3.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 1.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 1.8 GO:0071797 LUBAC complex(GO:0071797)
0.2 2.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 3.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 4.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 2.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 2.5 GO:0000792 heterochromatin(GO:0000792)
0.2 2.6 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.1 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 5.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 11.2 GO:0030027 lamellipodium(GO:0030027)
0.1 7.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 3.3 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 8.8 GO:0031201 SNARE complex(GO:0031201)
0.1 3.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.7 GO:0043195 terminal bouton(GO:0043195)
0.1 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 6.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.9 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 6.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 1.7 GO:0070382 exocytic vesicle(GO:0070382)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.0 3.8 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0043204 perikaryon(GO:0043204)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.5 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0044297 cell body(GO:0044297)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.9 GO:0045495 pole plasm(GO:0045495)
0.0 7.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 7.2 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 26.9 GO:0005829 cytosol(GO:0005829)
0.0 0.8 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 3.6 GO:0030424 axon(GO:0030424)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.8 GO:0010008 endosome membrane(GO:0010008)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 3.0 GO:0005764 lysosome(GO:0005764)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
1.2 4.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.8 2.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.8 4.9 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.6 3.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.6 1.9 GO:0031701 angiotensin receptor binding(GO:0031701)
0.6 3.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 3.5 GO:0035173 histone kinase activity(GO:0035173)
0.5 9.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.5 4.3 GO:0043515 kinetochore binding(GO:0043515)
0.5 1.4 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.4 1.3 GO:0045545 syndecan binding(GO:0045545)
0.4 6.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.4 1.6 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 6.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 10.3 GO:0051787 misfolded protein binding(GO:0051787)
0.4 1.4 GO:0070513 death domain binding(GO:0070513)
0.4 3.5 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.3 1.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 3.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 1.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 2.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 0.9 GO:0052855 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.3 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 7.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.3 1.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 4.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 3.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 1.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 2.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 11.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.2 1.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 1.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 4.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 4.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 6.4 GO:0035064 methylated histone binding(GO:0035064)
0.2 0.9 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 1.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 3.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 7.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 3.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.0 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 2.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 8.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 7.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 3.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.7 GO:0051117 ATPase binding(GO:0051117)
0.1 1.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 1.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 3.9 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 2.4 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 2.8 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.6 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 1.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 4.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 5.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 1.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.3 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 1.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 2.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.3 GO:0015926 glucosidase activity(GO:0015926)
0.1 4.7 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.1 6.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 3.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 3.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.0 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 6.4 GO:0060090 binding, bridging(GO:0060090)
0.0 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 7.3 GO:0008528 peptide receptor activity(GO:0001653) G-protein coupled peptide receptor activity(GO:0008528)
0.0 2.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 3.3 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 3.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 5.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 9.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)
0.0 3.6 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 3.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 12.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 3.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 5.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.2 6.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 3.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.5 PID BMP PATHWAY BMP receptor signaling
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 6.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 3.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 7.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 2.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 2.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 12.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 3.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 1.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 2.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 2.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 4.6 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling