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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hbp1

Z-value: 0.67

Motif logo

Transcription factors associated with hbp1

Gene Symbol Gene ID Gene Info
ENSDARG00000028517 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hbp1dr11_v1_chr25_-_3470910_34709100.294.0e-03Click!

Activity profile of hbp1 motif

Sorted Z-values of hbp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38301080 13.86 ENSDART00000105672
myosin binding protein C, fast type b
chr12_-_11457625 9.81 ENSDART00000012318
HtrA serine peptidase 1b
chr17_+_15297398 6.26 ENSDART00000156574
si:ch211-270g19.5
chr4_+_77948970 6.14 ENSDART00000149636
protein kinase C and casein kinase substrate in neurons 2
chr3_-_34528306 5.91 ENSDART00000023039
septin 9a
chr8_+_48613040 5.32 ENSDART00000121432
natriuretic peptide A
chr20_-_53996193 5.18 ENSDART00000004756
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr21_-_42831033 4.67 ENSDART00000160998
serine/threonine kinase 10
chr11_+_36243774 4.48 ENSDART00000023323
zgc:172270
chr21_+_45626136 4.21 ENSDART00000158742
interferon regulatory factor 1b
chr6_-_24103666 3.96 ENSDART00000164915
scinderin like a
chr22_+_10646928 3.67 ENSDART00000038465
Ras association (RalGDS/AF-6) domain family 1
chr22_+_35068046 3.65 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
chr3_+_11101585 3.64 ENSDART00000172103
somatostatin receptor 5
chr11_-_25418856 3.42 ENSDART00000013714
GATA binding protein 1a
chr25_-_35182347 3.40 ENSDART00000115210
anoctamin 9a
chr18_+_16986903 3.32 ENSDART00000142088
si:ch211-218c6.8
chr20_-_49729446 3.28 ENSDART00000111089
filamin A interacting protein 1b
chr1_-_33380340 3.15 ENSDART00000181515
CD99 molecule
chr21_+_6034783 3.08 ENSDART00000169613
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr1_-_33380011 2.96 ENSDART00000141347
ENSDART00000136383
CD99 molecule
chr6_+_38880166 2.93 ENSDART00000019939
ENSDART00000144286
bridging integrator 2b
chr11_+_45219558 2.81 ENSDART00000167828
transmembrane channel-like 6b
chr13_-_12660318 2.69 ENSDART00000008498
alcohol dehydrogenase 8a
chr15_+_37936458 2.62 ENSDART00000154491
si:ch73-380l3.2
chr20_+_48116476 2.55 ENSDART00000043938
translocation associated membrane protein 2
chr7_-_66868543 2.50 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr8_-_36399884 2.46 ENSDART00000108538
si:zfos-2070c2.3
chr6_+_23887314 2.28 ENSDART00000163188
zinc finger protein 648
chr18_-_26715655 2.27 ENSDART00000181497
MALT paracaspase 3
chr5_-_4230370 2.23 ENSDART00000133187
si:ch211-283g2.2
chr12_-_28548789 2.22 ENSDART00000153062
si:ch73-180n10.1
chr12_+_4260779 2.16 ENSDART00000081382
matrix metallopeptidase 25b
chr20_-_27086143 2.13 ENSDART00000008590
inositol-tetrakisphosphate 1-kinase a
chr4_-_73190246 2.13 ENSDART00000170842

chr3_+_4346854 2.11 ENSDART00000004273
si:dkey-73p2.3
chr7_-_25697285 2.07 ENSDART00000082620
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr19_-_32487469 2.07 ENSDART00000050130
guanosine monophosphate reductase
chr3_-_4303262 2.05 ENSDART00000112819
si:dkey-73p2.2
chr2_+_9560740 1.93 ENSDART00000003465
GIPC PDZ domain containing family, member 2
chr18_-_44285539 1.92 ENSDART00000137222
Pim proto-oncogene, serine/threonine kinase, related 179
chr24_-_31194847 1.91 ENSDART00000158808
calponin 3, acidic a
chr16_-_51299061 1.90 ENSDART00000148677
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr8_+_21437908 1.88 ENSDART00000142758
si:dkey-163f12.10
chr23_-_32092443 1.85 ENSDART00000133688
LETM1 domain containing 1
chr5_+_20112032 1.85 ENSDART00000130554
ISG15 ubiquitin-like modifier
chr25_-_7650335 1.78 ENSDART00000089034
myosin VAb
chr1_-_40735381 1.77 ENSDART00000093269
zgc:153642
chr12_+_23812530 1.73 ENSDART00000066331
supervillin a
chr3_-_36612877 1.65 ENSDART00000167164
si:dkeyp-72e1.7
chr6_-_40722200 1.63 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr20_-_44496245 1.58 ENSDART00000012229
FK506 binding protein 1b
chr5_+_30518036 1.56 ENSDART00000161836
hydroxymethylbilane synthase a
chr16_+_38201840 1.51 ENSDART00000044971
myosin IE, b
chr14_+_6159162 1.49 ENSDART00000128638
Bernardinelli-Seip congenital lipodystrophy 2, like
chr1_+_55643198 1.47 ENSDART00000060693
adhesion G protein-coupled receptor E7
chr20_+_36806398 1.42 ENSDART00000153317
ABRA C-terminal like
chr7_+_21272833 1.42 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr16_-_10834756 1.41 ENSDART00000188503
Rab acceptor 1 (prenylated)
chr16_-_9423735 1.38 ENSDART00000185645
chemokine (C-C motif) receptor 8.1
chr7_-_735118 1.31 ENSDART00000126424
si:cabz01078036.1
chr4_-_76205022 1.31 ENSDART00000159687
ENSDART00000187593
si:ch211-106j21.5
chr5_-_2721686 1.24 ENSDART00000169404
heat shock protein 5
chr15_-_2497568 1.23 ENSDART00000080398
sialidase 4
chr21_-_7035599 1.22 ENSDART00000139777
si:ch211-93g21.1
chr23_-_38054 1.22 ENSDART00000170393

chr13_-_12645584 1.20 ENSDART00000176216
alcohol dehydrogenase 8b
chr12_-_17201028 1.19 ENSDART00000020541
lipase, gastric
chr12_-_48970299 1.18 ENSDART00000163734
retinal G protein coupled receptor b
chr16_+_7242610 1.18 ENSDART00000081477
sorcin
chr8_+_27555314 1.14 ENSDART00000135568
ENSDART00000016696
ras homolog family member Cb
chr12_+_20412293 1.13 ENSDART00000115015
ENSDART00000177573
Rho GTPase activating protein 17a
chr5_+_9434288 1.10 ENSDART00000162089
UDP glucuronosyltransferase 2 family, polypeptide A7
chr4_-_32458542 1.10 ENSDART00000127211
si:dkey-16p6.1
chr15_+_31816835 1.05 ENSDART00000189658
ENSDART00000186634
ENSDART00000193032
ENSDART00000180401
furry homolog a (Drosophila)
chr3_+_62196672 1.02 ENSDART00000097312
SCO1 cytochrome c oxidase assembly protein
chr16_-_52916248 0.95 ENSDART00000113931
zinc finger, DHHC-type containing 11
chr4_-_76027176 0.95 ENSDART00000165718
si:dkey-71l4.1
chr4_-_75505048 0.91 ENSDART00000163665
si:dkey-71l4.5
chr7_+_51816321 0.89 ENSDART00000073846
si:ch211-122f10.4
chr8_-_4010887 0.89 ENSDART00000163678
myotubularin related protein 3
chr23_-_11128601 0.89 ENSDART00000131232
contactin 3a, tandem duplicate 2
chr6_+_29402997 0.87 ENSDART00000104298
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 5
chr2_-_11027258 0.84 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
single stranded DNA binding protein 3a
chr23_+_27740592 0.84 ENSDART00000137875
desert hedgehog
chr18_-_25276262 0.83 ENSDART00000131855
perilipin 1
chr14_+_6159356 0.80 ENSDART00000157730
Bernardinelli-Seip congenital lipodystrophy 2, like
chr4_-_9909371 0.78 ENSDART00000102656
si:dkey-22l11.6
chr13_-_39160018 0.78 ENSDART00000168795
collagen, type IX, alpha 1b
chr4_-_68868229 0.76 ENSDART00000159219
si:dkey-264f17.5
chr5_+_20437124 0.76 ENSDART00000159001
transmembrane protein 119a
chr4_+_56379907 0.76 ENSDART00000169142
si:dkey-41c6.3
chr16_-_47427016 0.73 ENSDART00000074575
septin 7b
chr21_-_23307653 0.73 ENSDART00000140284
ENSDART00000134103
zinc finger and BTB domain containing 16a
chr12_+_47698356 0.67 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr4_+_5249494 0.67 ENSDART00000150391
si:ch211-214j24.14
chr15_+_45643787 0.65 ENSDART00000055995
ENSDART00000157750
S-antigen; retina and pineal gland (arrestin) b
chr6_+_42693288 0.65 ENSDART00000155010
si:ch211-207d10.2
chr13_+_18515126 0.64 ENSDART00000044697
toll-like receptor 4b, duplicate a
chr4_+_31328329 0.62 ENSDART00000189539
si:rp71-5o12.3
chr2_+_19163965 0.61 ENSDART00000166073
ELOVL fatty acid elongase 1a
chr18_+_22138924 0.61 ENSDART00000183961
RHO family interacting cell polarization regulator 1
chr24_+_26017094 0.60 ENSDART00000137851
transferrin receptor 1b
chr22_+_7923713 0.60 ENSDART00000167210

chr25_-_31698550 0.58 ENSDART00000058400
laminin, beta 4
chr1_-_59252973 0.58 ENSDART00000167061
si:ch1073-286c18.5
chr21_-_22648007 0.55 ENSDART00000121788
grass carp reovirus (GCRV)-induced gene 2l
chr17_+_49096222 0.49 ENSDART00000185900
T cell lymphoma invasion and metastasis 2a
chr23_+_10352921 0.49 ENSDART00000081193
si:ch211-133j6.3
chr23_-_45111637 0.49 ENSDART00000179776
si:ch73-168d20.1
chr14_-_17262082 0.47 ENSDART00000173944
ENSDART00000172317
ENSDART00000171064
janus kinase and microtubule interacting protein 1
chr7_-_4461104 0.47 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr18_+_44795711 0.46 ENSDART00000110229
ENSDART00000188262
ENSDART00000139526
family with sequence similarity 118, member B
chr22_-_16154771 0.45 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr1_-_633356 0.44 ENSDART00000171019
amyloid beta (A4) precursor protein a
chr10_+_40768203 0.43 ENSDART00000171994
ENSDART00000140343
trace amine associated receptor 19d
chr4_-_59159690 0.43 ENSDART00000164706
zinc finger protein 1149
chr25_+_23777469 0.41 ENSDART00000067179
mitochondrial ribosomal protein L23
chr5_-_19444930 0.41 ENSDART00000136259
ENSDART00000188499
potassium channel tetramerization domain containing 10
chr20_+_47491247 0.41 ENSDART00000113412
lin-28 homolog B (C. elegans)
chr7_+_27691647 0.41 ENSDART00000079091
cytochrome P450, family 2, subfamily R, polypeptide 1
chr14_-_34512859 0.40 ENSDART00000140368
si:ch211-232m8.3
chr24_+_13735616 0.40 ENSDART00000184267
musculin (activated B-cell factor-1)
chr14_-_46238186 0.39 ENSDART00000173245
si:ch211-113d11.6
chr6_-_379248 0.38 ENSDART00000172052
si:zfos-169g10.2
chr4_-_55641422 0.38 ENSDART00000165178
zinc finger protein 1074
chr10_+_8554929 0.33 ENSDART00000190849
TBC1 domain family, member 10Ab
chr6_+_42693114 0.32 ENSDART00000154353
si:ch211-207d10.2
chr4_+_77920666 0.32 ENSDART00000129523
tubulin tyrosine ligase-like family, member 1
chr13_-_10620652 0.31 ENSDART00000135000
ENSDART00000191587
si:ch73-54n14.2
calmodulin-lysine N-methyltransferase
chr5_+_12888816 0.29 ENSDART00000139632
galactose-3-O-sulfotransferase 1a
chr14_-_48245816 0.27 ENSDART00000172452
relaxin/insulin-like family peptide receptor 1
chr16_+_21917673 0.27 ENSDART00000170604
zinc finger protein 687a
chr17_-_27419499 0.27 ENSDART00000186773
YTH N(6)-methyladenosine RNA binding protein 2
chr20_+_1088658 0.25 ENSDART00000162991

chr1_+_40263671 0.25 ENSDART00000045697
zgc:56493
chr18_-_25276932 0.24 ENSDART00000076183
perilipin 1
chr13_-_28672474 0.24 ENSDART00000164508
5'-nucleotidase, cytosolic IIa
chr15_+_1199407 0.23 ENSDART00000163827
major facilitator superfamily domain containing 1
chr8_+_32722842 0.22 ENSDART00000147594
hemicentin 2
chr18_+_9362455 0.22 ENSDART00000187025
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr22_+_1821718 0.21 ENSDART00000132220
zinc finger protein 1002
chr14_-_30945515 0.20 ENSDART00000161540
si:zfos-80g12.1
chr4_+_32649955 0.18 ENSDART00000135750
zinc finger protein 1042
chr7_+_26172682 0.18 ENSDART00000173631
si:ch211-196f2.7
chr21_+_38855551 0.14 ENSDART00000171977
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr22_-_7778265 0.11 ENSDART00000097276
si:ch73-44m9.3
chr7_+_6317866 0.10 ENSDART00000173397
si:ch211-220f21.3
chr24_+_26997798 0.09 ENSDART00000089506
La ribonucleoprotein domain family, member 4B
chr17_-_15188440 0.08 ENSDART00000151885
WD repeat and HMG-box DNA binding protein 1
chr21_+_21612214 0.08 ENSDART00000008099
B9 domain containing 2
chr10_+_24660225 0.08 ENSDART00000190695
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr9_-_50000144 0.07 ENSDART00000123416
sodium channel, voltage-gated, type I, alpha
chr1_+_29070661 0.05 ENSDART00000192015
cystathionine-beta-synthase a
chr10_+_24660017 0.03 ENSDART00000079597
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr1_+_7414318 0.02 ENSDART00000127426
si:ch73-383l1.1
chr18_+_618005 0.02 ENSDART00000189667
protogenin homolog a (Gallus gallus)
chr23_-_24343363 0.00 ENSDART00000166392
family with sequence similarity 131, member C

Network of associatons between targets according to the STRING database.

First level regulatory network of hbp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:1905072 cardiac jelly development(GO:1905072)
1.3 5.2 GO:1904407 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
1.2 6.1 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
1.1 10.6 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.9 3.4 GO:0030224 monocyte differentiation(GO:0030224)
0.7 2.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.6 3.9 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.5 2.1 GO:0001778 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.5 2.9 GO:0071800 podosome assembly(GO:0071800)
0.4 4.2 GO:0050688 regulation of defense response to virus(GO:0050688)
0.4 6.3 GO:0043462 regulation of ATPase activity(GO:0043462)
0.3 3.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.3 2.3 GO:0034389 lipid particle organization(GO:0034389)
0.3 1.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.3 4.7 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.3 2.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.3 0.8 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.2 2.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 3.6 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.2 5.7 GO:0051014 actin filament severing(GO:0051014)
0.2 2.5 GO:0032264 IMP salvage(GO:0032264)
0.2 1.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.6 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 3.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.8 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 1.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 2.1 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.5 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 0.3 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 1.2 GO:0042026 protein refolding(GO:0042026)
0.1 3.7 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 1.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 3.3 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 0.4 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 0.7 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 6.6 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 3.3 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.0 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 3.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 14.3 GO:0060537 muscle tissue development(GO:0060537)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.2 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 3.7 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.2 GO:0007602 phototransduction(GO:0007602)
0.0 0.3 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1902560 GMP reductase complex(GO:1902560)
0.4 2.9 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 5.2 GO:0043209 myelin sheath(GO:0043209)
0.3 6.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 10.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 6.6 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.1 GO:0030315 T-tubule(GO:0030315)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.4 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 3.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 15.2 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.2 3.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.8 3.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.7 2.1 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.7 2.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.5 4.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 9.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 1.6 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.2 2.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 3.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 2.6 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.9 GO:0031386 protein tag(GO:0031386)
0.1 1.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 5.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.8 GO:0005113 patched binding(GO:0005113)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 5.3 GO:0051427 hormone receptor binding(GO:0051427)
0.1 5.2 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 7.6 GO:0060090 binding, bridging(GO:0060090)
0.0 1.9 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 3.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 7.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.9 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.3 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.7 PID P53 REGULATION PATHWAY p53 pathway
0.1 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 3.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)