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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hinfp

Z-value: 0.48

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Transcription factors associated with hinfp

Gene Symbol Gene ID Gene Info
ENSDARG00000004851 histone H4 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hinfpdr11_v1_chr5_+_30596477_305964770.084.2e-01Click!

Activity profile of hinfp motif

Sorted Z-values of hinfp motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_41147818 3.67 ENSDART00000167339
ENSDART00000192730
muscle segment homeobox 2b
chr8_+_11687586 2.60 ENSDART00000146241
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr3_+_6469754 2.42 ENSDART00000185809
nucleoporin 85
chr14_-_2602445 2.38 ENSDART00000166910
eukaryotic translation termination factor 1a
chr14_+_52440161 2.28 ENSDART00000168437
DP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, like
chr20_-_2725594 2.28 ENSDART00000152120
akirin 2
chr9_+_8408054 2.13 ENSDART00000144373
zgc:153499
chr11_-_25853212 2.10 ENSDART00000145655
transmembrane protein 51b
chr19_+_48290786 2.07 ENSDART00000165986
zgc:101785
chr11_+_5926850 1.96 ENSDART00000104364
ribosomal protein S15
chr24_+_5799764 1.93 ENSDART00000154482
si:ch211-157j23.2
chr22_+_11775269 1.91 ENSDART00000140272
keratin 96
chr8_+_11687254 1.87 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr3_-_44012748 1.82 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
interleukin 4 receptor, tandem duplicate 1
chr13_-_3155243 1.79 ENSDART00000139183
ENSDART00000050934
protein kinase domain containing, cytoplasmic a
chr10_-_39130839 1.76 ENSDART00000061274
ENSDART00000148648
ribosomal protein S25
chr19_-_31765615 1.67 ENSDART00000103636
si:dkeyp-120h9.1
chr21_+_28747069 1.66 ENSDART00000014058
zgc:100829
chr5_+_47862636 1.64 ENSDART00000139824
RAS p21 protein activator (GTPase activating protein) 1a
chr3_-_44059902 1.64 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr10_-_21362071 1.59 ENSDART00000125167
avidin
chr21_+_28747236 1.59 ENSDART00000137874
zgc:100829
chr9_+_8407778 1.58 ENSDART00000102754
ENSDART00000178144
zgc:153499
chr10_-_21362320 1.55 ENSDART00000189789
avidin
chr23_+_642001 1.52 ENSDART00000030643
ENSDART00000124850
interferon regulatory factor 10
chr19_-_11425542 1.52 ENSDART00000177875
ENSDART00000080762
septin 7a
chr1_+_53945934 1.46 ENSDART00000052838
actin, alpha 1a, skeletal muscle
chr10_-_320153 1.40 ENSDART00000161493
v-akt murine thymoma viral oncogene homolog 2, like
chr7_-_62244744 1.29 ENSDART00000192522
ENSDART00000170635
ENSDART00000073872
cholecystokinin A receptor
chr22_+_38310957 1.28 ENSDART00000040550
Tnf receptor-associated factor 5
chr24_+_35564668 1.26 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr5_+_38596630 1.26 ENSDART00000015136
monoacylglycerol O-acyltransferase 3b
chr23_+_1216215 1.22 ENSDART00000165957
utrophin
chr5_+_47863153 1.20 ENSDART00000051518
RAS p21 protein activator (GTPase activating protein) 1a
chr2_+_16173999 1.13 ENSDART00000177639
ENSDART00000157601
ENSDART00000190186
ENSDART00000045933
SH3-domain GRB2-like endophilin B1b
chr3_+_25849560 1.12 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr16_-_27564256 1.07 ENSDART00000078297
zgc:153215
chr20_-_2725930 1.07 ENSDART00000081643
akirin 2
chr21_-_41839683 1.04 ENSDART00000160908
ENSDART00000137630
chaperonin containing TCP1, subunit 6A (zeta 1)
chr25_-_10791437 0.95 ENSDART00000127054

chr11_+_1551603 0.95 ENSDART00000185383
ENSDART00000121489
ENSDART00000040577
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr23_-_44848961 0.95 ENSDART00000136839
wu:fb72h05
chr17_+_53297822 0.87 ENSDART00000168297
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr11_+_6010177 0.84 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
GTP binding protein 3, mitochondrial
chr2_+_15048410 0.83 ENSDART00000058484
calponin 3, acidic b
chr19_+_3653976 0.81 ENSDART00000125673
neural precursor cell expressed, developmentally down-regulated 9
chr6_-_58975010 0.81 ENSDART00000144911
ENSDART00000144514
methionyl-tRNA synthetase
chr22_+_31059919 0.80 ENSDART00000077063
SEC13 homolog, nuclear pore and COPII coat complex component
chr8_+_29962635 0.79 ENSDART00000007640
patched 1
chr7_-_69184420 0.79 ENSDART00000168311
ENSDART00000159239
ENSDART00000161319
ubiquitin specific peptidase 10
chr2_-_1468258 0.78 ENSDART00000114431
glycosylphosphatidylinositol anchor attachment 1
chr15_-_25319663 0.77 ENSDART00000042218
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a
chr5_-_47975440 0.77 ENSDART00000145665
ENSDART00000007057
cyclin H
chr10_+_21444654 0.77 ENSDART00000140113
ENSDART00000184386
ENSDART00000019252
F-box and WD repeat domain containing 11b
chr14_-_16423200 0.75 ENSDART00000108868
ENSDART00000161793
mastermind-like transcriptional coactivator 1
chr10_-_35321625 0.72 ENSDART00000131268
rhomboid domain containing 2
chr25_-_21763750 0.70 ENSDART00000089596
transmembrane protein 168b
chr3_-_6441619 0.67 ENSDART00000157771
ENSDART00000166758
small ubiquitin-like modifier 2b
chr25_-_36248053 0.62 ENSDART00000134928
nuclear factor of activated T cells 3b
chr23_+_1078072 0.62 ENSDART00000159263
ENSDART00000053527
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2b
chr4_-_77557279 0.62 ENSDART00000180113

chr20_-_2298970 0.61 ENSDART00000136067
si:ch73-18b11.1
chr11_+_6009984 0.61 ENSDART00000185680
GTP binding protein 3, mitochondrial
chr8_+_29963024 0.59 ENSDART00000149372
patched 1
chr12_-_290413 0.57 ENSDART00000152496
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr3_+_60962410 0.56 ENSDART00000042674
helicase with zinc finger
chr20_+_42246948 0.55 ENSDART00000061135
golgi-associated PDZ and coiled-coil motif containing
chr16_+_2905150 0.53 ENSDART00000109980
leucyl-tRNA synthetase 2, mitochondrial
chr19_+_58954 0.53 ENSDART00000162379
collagen, type XIV, alpha 1b
chr7_-_48396193 0.52 ENSDART00000083555
SIN3 transcription regulator family member Ab
chr1_+_54069450 0.50 ENSDART00000108601
ENSDART00000187878
DDB1 and CUL4 associated factor 15
chr19_-_31900893 0.50 ENSDART00000113797
zinc finger and BTB domain containing 10
chr19_+_8612839 0.49 ENSDART00000144925
sorting nexin family member 27a
chr14_+_16937997 0.48 ENSDART00000163013
ENSDART00000167856
LIM and calponin homology domains 1b
chr7_-_39611109 0.46 ENSDART00000149991
protein tyrosine phosphatase, receptor type, J a
chr24_+_28383278 0.44 ENSDART00000018095
SH3-domain GRB2-like endophilin B1a
chr25_-_26833100 0.41 ENSDART00000014052
nei-like DNA glycosylase 1
chr1_-_40132831 0.40 ENSDART00000135647
si:ch211-113e8.10
chr16_+_40954481 0.39 ENSDART00000058587
glycogen synthase kinase binding protein
chr4_+_71086017 0.37 ENSDART00000159113
si:dkeyp-80d11.10
chr8_+_36983559 0.34 ENSDART00000127053
lysine (K)-specific demethylase 5C
chr6_-_40771813 0.34 ENSDART00000076200
H1 histone family, member X
chr5_+_64407896 0.33 ENSDART00000173886
si:ch1073-363c19.3
chr5_-_63065912 0.33 ENSDART00000161149
family with sequence similarity 57 member A
chr23_+_30707837 0.32 ENSDART00000016096
DnaJ (Hsp40) homolog, subfamily C, member 11a
chr16_+_25806400 0.32 ENSDART00000154652
immunity-related GTPase family, q1
chr9_+_56422311 0.31 ENSDART00000171958
G protein-coupled receptor 39
chr11_+_2710530 0.31 ENSDART00000132768
ENSDART00000030921
ENSDART00000040147
mitogen-activated protein kinase 14b
chr6_+_34038963 0.29 ENSDART00000057732
ENSDART00000192496
adaptor-related protein complex 1, mu 3 subunit
chr17_-_24866964 0.27 ENSDART00000190601
ENSDART00000192547
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr22_-_24900121 0.25 ENSDART00000147643
si:dkey-4c23.3
chr24_+_17345521 0.25 ENSDART00000024722
ENSDART00000154250
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr18_-_17020231 0.24 ENSDART00000129146
TBC1 domain family, member 15
chr7_+_28612671 0.24 ENSDART00000019991
solute carrier family 7, member 6 opposite strand
chr13_+_28618086 0.22 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr8_+_21225064 0.16 ENSDART00000129210
cryptochrome circadian clock 1ba
chr17_-_24866727 0.15 ENSDART00000027957
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr23_+_45845423 0.15 ENSDART00000183404
lamin L3
chr5_-_23117078 0.15 ENSDART00000051529
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr16_-_17586883 0.14 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr22_+_569565 0.12 ENSDART00000037069
ubiquitin specific peptidase 49
chr4_+_14899720 0.11 ENSDART00000187456
aldo-keto reductase family 1, member B1 (aldose reductase)
chr7_-_29231686 0.11 ENSDART00000173780
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr24_-_1023112 0.11 ENSDART00000147508
ENSDART00000066863
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr5_-_18961694 0.08 ENSDART00000142531
ENSDART00000090521
ankyrin repeat and LEM domain containing 2
chr21_-_12749501 0.08 ENSDART00000179724

chr5_+_27429872 0.07 ENSDART00000087894
zgc:165555
chr9_+_56422517 0.05 ENSDART00000168620
G protein-coupled receptor 39
chr1_+_57347888 0.04 ENSDART00000104222
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr21_-_1742159 0.01 ENSDART00000151049
one cut homeobox 2
chr7_+_9880811 0.01 ENSDART00000128376
lines homolog 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hinfp

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.5 1.5 GO:0090131 mesenchyme migration(GO:0090131)
0.5 2.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.7 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.3 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.6 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.2 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.4 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.2 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 2.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.5 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 4.3 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 3.1 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 1.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.8 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 2.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.5 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.6 GO:0035194 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.8 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 3.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.5 GO:0005869 dynactin complex(GO:0005869)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.8 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 3.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.5 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) cleavage furrow(GO:0032154) septin cytoskeleton(GO:0032156) cell surface furrow(GO:0097610)
0.0 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.4 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.8 2.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.6 3.1 GO:0009374 biotin binding(GO:0009374)
0.3 1.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 3.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.5 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 1.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.7 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 3.5 GO:0019838 growth factor binding(GO:0019838)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 3.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation