Project

PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

Navigation
Downloads

Results for hmga1a

Z-value: 0.68

Motif logo

logo of

Transcription factors associated with hmga1a

Gene Symbol Gene ID Gene Info
hmga1a
ENSDARG00000028335 high mobility group AT-hook 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmga1adr11_v1_chr23_-_3759692_37596920.132.2e-01Click!

Activity profile of hmga1a motif

Sorted Z-values of hmga1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_45439903 6.16 ENSDART00000170729
NPNT (1 of many)
nephronectin
chr6_-_35472923 5.05 ENSDART00000185907
rgs8
regulator of G protein signaling 8
chr6_+_42545797 5.03 ENSDART00000154333
camkva
CaM kinase-like vesicle-associated a
chr6_+_3827751 4.97 ENSDART00000003008
ENSDART00000122348
gad1b
glutamate decarboxylase 1b
chr11_-_4235811 4.31 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr23_-_27633730 4.02 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr6_+_3828560 3.88 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr6_-_58764672 3.81 ENSDART00000154322
soat2
sterol O-acyltransferase 2
chr12_+_46386983 3.48 ENSDART00000183982
BX005305.3
Danio rerio legumain (LOC100005356), mRNA.
chr24_-_29963858 3.48 ENSDART00000183442
CR352310.1

chr7_-_69521481 3.14 ENSDART00000148465
slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr12_+_46425800 3.07 ENSDART00000191965
BX005305.1

chr12_+_46512881 2.89 ENSDART00000105454
CU855711.1

chr5_-_20814576 2.83 ENSDART00000098682
ENSDART00000147639
si:ch211-225b11.1
si:ch211-225b11.1
chr11_-_16975190 2.70 ENSDART00000122222
suclg2
succinate-CoA ligase, GDP-forming, beta subunit
chr6_-_58757131 2.66 ENSDART00000083582
soat2
sterol O-acyltransferase 2
chr12_+_46462090 2.59 ENSDART00000130748
BX005305.2

chr15_+_17030473 2.54 ENSDART00000129407
plin2
perilipin 2
chr12_+_46404307 2.53 ENSDART00000185011
BX005305.4

chr12_+_21525496 2.49 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr17_-_21200406 2.49 ENSDART00000104708
abhd12
abhydrolase domain containing 12
chr12_+_46443477 2.48 ENSDART00000191873
BX005305.1

chr3_-_33437796 2.47 ENSDART00000075499
si:dkey-283b1.7
si:dkey-283b1.7
chr12_+_46483618 2.45 ENSDART00000186970
BX005305.5

chr7_+_48999723 2.45 ENSDART00000182699
ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr10_+_44584614 2.43 ENSDART00000163523
sez6l
seizure related 6 homolog (mouse)-like
chr21_-_588858 2.14 ENSDART00000168983
TMEM38B
transmembrane protein 38B
chr1_+_19849168 2.08 ENSDART00000111454
si:dkey-82j4.2
si:dkey-82j4.2
chr14_-_2348917 2.07 ENSDART00000159004
si:ch73-233f7.8
si:ch73-233f7.8
chr16_-_15988320 2.04 ENSDART00000160883
CABZ01060453.1

chr8_+_42917515 1.98 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr25_+_581227 1.89 ENSDART00000126863
nell2a
neural EGFL like 2a
chr11_-_34151487 1.84 ENSDART00000173039
atp13a3
ATPase 13A3
chr2_-_10062575 1.82 ENSDART00000091726
fam78ba
family with sequence similarity 78, member B a
chr12_-_36740781 1.80 ENSDART00000105484
si:ch211-216b21.2
si:ch211-216b21.2
chr7_+_15871156 1.76 ENSDART00000145946
pax6b
paired box 6b
chr18_+_31410652 1.75 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr4_+_13568469 1.74 ENSDART00000171235
ENSDART00000136152
calua
calumenin a
chr12_+_46841918 1.64 ENSDART00000157464
adkb
adenosine kinase b
chr8_+_54081819 1.62 ENSDART00000005857
ENSDART00000161795
prickle2a
prickle homolog 2a
chr13_+_1089942 1.62 ENSDART00000054322
cnrip1b
cannabinoid receptor interacting protein 1b
chr15_-_33807758 1.62 ENSDART00000158445
pds5b
PDS5 cohesin associated factor B
chr7_-_33130552 1.59 ENSDART00000127006
mns1
meiosis-specific nuclear structural 1
chr6_-_7123210 1.51 ENSDART00000041304
atg3
autophagy related 3
chr20_+_26349002 1.50 ENSDART00000152842
syne1a
spectrin repeat containing, nuclear envelope 1a
chr15_+_17030941 1.48 ENSDART00000062069
plin2
perilipin 2
chr9_-_12885201 1.46 ENSDART00000124957
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr1_+_49814461 1.46 ENSDART00000132405
lef1
lymphoid enhancer-binding factor 1
chr3_+_36515376 1.44 ENSDART00000161652
si:dkeyp-72e1.9
si:dkeyp-72e1.9
chr5_-_51830997 1.44 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr21_+_21743599 1.42 ENSDART00000101700
pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr15_+_15856178 1.36 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr23_+_38940700 1.34 ENSDART00000065331
sall4
spalt-like transcription factor 4
chr16_-_12236362 1.32 ENSDART00000114759
lpcat3
lysophosphatidylcholine acyltransferase 3
chr6_-_10740365 1.30 ENSDART00000150942
sp3b
Sp3b transcription factor
chr1_+_47335038 1.30 ENSDART00000188153
bcl9
B cell CLL/lymphoma 9
chr12_-_656540 1.29 ENSDART00000172651
sult2st2
sulfotransferase family 2, cytosolic sulfotransferase 2
chr8_+_40644838 1.28 ENSDART00000169311
adra2b
adrenoceptor alpha 2B
chr17_-_5769196 1.28 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr2_+_32846602 1.26 ENSDART00000056649
tmem53
transmembrane protein 53
chr17_-_40110782 1.23 ENSDART00000126929
si:dkey-187k19.2
si:dkey-187k19.2
chr24_-_16975960 1.20 ENSDART00000180687
klhl15
kelch-like family member 15
chr7_+_33130639 1.19 ENSDART00000142450
ENSDART00000173967
ENSDART00000173832
zgc:153219
si:ch211-194p6.7
zgc:153219
si:ch211-194p6.7
chr4_+_26053044 1.18 ENSDART00000039877
SCYL2
si:ch211-244b2.1
chr23_+_45512825 1.15 ENSDART00000064846
prelid1b
PRELI domain containing 1b
chr3_+_62161184 1.13 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr1_-_14258409 1.12 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr4_-_4535189 1.09 ENSDART00000057519
zgc:194209
zgc:194209
chr1_+_41690402 1.04 ENSDART00000177298
fbxo41
F-box protein 41
chr15_+_44135726 1.01 ENSDART00000192151
CU655961.2

chr14_-_38828057 1.01 ENSDART00000186088
spdl1
spindle apparatus coiled-coil protein 1
chr10_+_20364009 0.99 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr6_-_2222707 0.99 ENSDART00000022179
prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr13_+_41917606 0.98 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr15_+_888704 0.96 ENSDART00000182796
si:dkey-7i4.9
si:dkey-7i4.9
chr17_-_1703259 0.96 ENSDART00000156489
xgb
x globin
chr24_-_35534273 0.93 ENSDART00000026578
ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr25_-_13789955 0.92 ENSDART00000167742
ENSDART00000165116
ENSDART00000171461
ckap5
cytoskeleton associated protein 5
chr3_+_26019426 0.91 ENSDART00000135389
ENSDART00000182411
foxred2
FAD-dependent oxidoreductase domain containing 2
chr9_+_36314867 0.91 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr15_-_31508221 0.79 ENSDART00000121464
si:dkey-1m11.5
si:dkey-1m11.5
chr25_-_17910714 0.79 ENSDART00000191586
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr5_+_38612134 0.76 ENSDART00000135600
ENSDART00000181144
si:ch211-271e10.2
si:ch211-271e10.2
chr2_+_25839193 0.75 ENSDART00000078634
eif5a2
eukaryotic translation initiation factor 5A2
chr11_+_5817202 0.74 ENSDART00000126084
ctdspl3
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr14_-_38827442 0.72 ENSDART00000160000
spdl1
spindle apparatus coiled-coil protein 1
chr14_+_11909966 0.71 ENSDART00000171829
frmpd3
FERM and PDZ domain containing 3
chr14_+_35237613 0.70 ENSDART00000163465
ebf3a
early B cell factor 3a
chr7_-_64971839 0.69 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr10_+_42733210 0.68 ENSDART00000189832
CABZ01063556.1

chr19_+_29808471 0.68 ENSDART00000186428
hdac1
histone deacetylase 1
chr14_-_33521071 0.67 ENSDART00000052789
c1galt1c1
C1GALT1-specific chaperone 1
chr5_+_41476443 0.66 ENSDART00000145228
ENSDART00000137981
ENSDART00000142538
pias2
protein inhibitor of activated STAT, 2
chr20_-_874807 0.64 ENSDART00000020506
snx14
sorting nexin 14
chr6_+_22679610 0.64 ENSDART00000102701
zmp:0000000634
zmp:0000000634
chr24_-_31090948 0.63 ENSDART00000176799
hccsb
holocytochrome c synthase b
chr19_+_29808699 0.62 ENSDART00000051799
ENSDART00000164205
hdac1
histone deacetylase 1
chr16_-_24561354 0.60 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr24_+_39137001 0.55 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr22_-_16416882 0.54 ENSDART00000062749
cts12
cathepsin 12
chr11_-_12051502 0.52 ENSDART00000183462
socs7
suppressor of cytokine signaling 7
chr14_+_8710568 0.50 ENSDART00000169505
kcnk4a
potassium channel, subfamily K, member 4a
chr11_-_12051283 0.46 ENSDART00000170516
socs7
suppressor of cytokine signaling 7
chr4_-_73372362 0.44 ENSDART00000182312
ENSDART00000158404
ENSDART00000174367
si:cabz01021430.2
zgc:171727
si:cabz01021426.2
si:cabz01021430.2
zgc:171727
si:cabz01021426.2
chr4_+_73872345 0.41 ENSDART00000174075
CABZ01069022.1

chr16_-_26232411 0.39 ENSDART00000139355
arhgef1b
Rho guanine nucleotide exchange factor (GEF) 1b
chr23_-_28347039 0.35 ENSDART00000145072
neurod4
neuronal differentiation 4
chr15_+_3825117 0.33 ENSDART00000183315
CABZ01061591.1

chr17_-_23221504 0.32 ENSDART00000156411
fam98a
family with sequence similarity 98, member A
chr4_+_17245005 0.31 ENSDART00000027645
casc1
cancer susceptibility candidate 1
chr2_-_31791633 0.30 ENSDART00000180662
retreg1
reticulophagy regulator 1
chr1_+_2112726 0.30 ENSDART00000131714
ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr14_+_34951202 0.28 ENSDART00000047524
ENSDART00000115105
il12ba
interleukin 12Ba
chr18_-_35407695 0.27 ENSDART00000191845
ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr15_+_47440477 0.21 ENSDART00000002384
phox2a
paired-like homeobox 2a
chr4_+_19127973 0.19 ENSDART00000136611
si:dkey-21o22.2
si:dkey-21o22.2
chr4_+_17245217 0.18 ENSDART00000184215
ENSDART00000110908
casc1
cancer susceptibility candidate 1
chr25_+_19739665 0.18 ENSDART00000067353
zgc:101783
zgc:101783
chr12_+_33919502 0.17 ENSDART00000085888
trim8b
tripartite motif containing 8b
chr11_-_18468570 0.12 ENSDART00000155474
ENSDART00000193869
fgd5a
FYVE, RhoGEF and PH domain containing 5a
chr6_+_8630355 0.11 ENSDART00000161749
ENSDART00000193976
tspeara
thrombospondin-type laminin G domain and EAR repeats a
chr17_+_31739418 0.11 ENSDART00000155073
ENSDART00000156180
arhgap5
Rho GTPase activating protein 5
chr24_-_18477672 0.10 ENSDART00000126928
ENSDART00000158393
si:dkey-73n8.3
si:dkey-73n8.3
chr8_+_49975160 0.08 ENSDART00000156403
ENSDART00000080135
gfpt1
glutamine--fructose-6-phosphate transaminase 1
chr18_+_328689 0.03 ENSDART00000167841
ss18l2
synovial sarcoma translocation gene on chromosome 18-like 2
chr5_-_39805874 0.03 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr5_+_32831561 0.03 ENSDART00000169358
ENSDART00000192078
si:ch211-208h16.4
si:ch211-208h16.4
chr13_-_41917050 0.01 ENSDART00000110549
cisd1
CDGSH iron sulfur domain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of hmga1a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.3 5.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.7 6.5 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.7 2.0 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.5 2.5 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.5 1.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.4 4.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 1.5 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.3 1.6 GO:0044209 AMP salvage(GO:0044209)
0.3 1.3 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.3 1.8 GO:0003311 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.3 1.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 1.3 GO:0033687 osteoblast proliferation(GO:0033687)
0.2 1.6 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 1.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.6 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.8 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 1.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 2.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 1.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.4 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 2.5 GO:0036269 swimming behavior(GO:0036269)
0.0 4.3 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 1.3 GO:0051923 sulfation(GO:0051923)
0.0 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 2.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0006301 postreplication repair(GO:0006301)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.6 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 2.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0009648 photoperiodism(GO:0009648)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 4.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0021703 locus ceruleus development(GO:0021703)
0.0 2.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 2.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.3 1.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 5.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 1.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 2.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.5 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 4.0 GO:0005811 lipid particle(GO:0005811)
0.1 0.3 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 1.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.2 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.4 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.6 6.5 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.9 2.7 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.5 1.5 GO:0019777 Atg12 transferase activity(GO:0019777)
0.3 1.6 GO:0004001 adenosine kinase activity(GO:0004001)
0.3 2.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 1.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.7 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.6 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 3.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.4 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 1.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.0 GO:0016208 AMP binding(GO:0016208)
0.0 6.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 7.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 4.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 1.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 1.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 5.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 4.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins