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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hmx2_hmx3a

Z-value: 1.13

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Transcription factors associated with hmx2_hmx3a

Gene Symbol Gene ID Gene Info
ENSDARG00000070954 H6 family homeobox 2
ENSDARG00000115364 H6 family homeobox 2
ENSDARG00000070955 H6 family homeobox 3a
ENSDARG00000115051 H6 family homeobox 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmx3adr11_v1_chr17_-_21793113_21793113-0.355.9e-04Click!
hmx2dr11_v1_chr17_-_21784152_21784152-0.093.8e-01Click!

Activity profile of hmx2_hmx3a motif

Sorted Z-values of hmx2_hmx3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_38301080 24.24 ENSDART00000105672
myosin binding protein C, fast type b
chr25_+_31267268 13.93 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr5_-_25723079 10.68 ENSDART00000014013
guanine deaminase
chr16_-_13516745 6.81 ENSDART00000145410
si:dkeyp-69b9.3
chr6_+_29410986 6.65 ENSDART00000065293
ubiquitin specific peptidase 13
chr8_-_39739627 6.01 ENSDART00000135422
ENSDART00000067844
si:ch211-170d8.5
chr24_-_10014512 6.00 ENSDART00000124341
ENSDART00000191630
zgc:171474
chr11_+_36243774 5.82 ENSDART00000023323
zgc:172270
chr24_-_9997948 5.73 ENSDART00000136274
si:ch211-146l10.7
chr8_-_39739056 5.69 ENSDART00000147992
si:ch211-170d8.5
chr13_+_24280380 5.69 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr1_-_19845378 5.63 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr10_-_1961930 5.45 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr21_+_40484088 5.39 ENSDART00000161919
coronin 6
chr3_-_39152478 4.78 ENSDART00000154550
si:dkeyp-57f11.2
chr18_+_13792490 4.76 ENSDART00000136754
cadherin 13, H-cadherin (heart)
chr23_+_36083529 4.51 ENSDART00000053295
ENSDART00000130260
homeobox C10a
chr8_+_50534948 4.45 ENSDART00000174435
phosphatidylethanolamine binding protein 4
chr8_-_53166975 4.29 ENSDART00000114683
rabenosyn, RAB effector
chr25_-_26018240 4.20 ENSDART00000150800
acyl-CoA synthetase bubblegum family member 1
chr5_+_37032038 4.18 ENSDART00000045036
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr2_+_56657804 4.06 ENSDART00000113964
RNA polymerase II subunit E
chr11_+_18130300 4.05 ENSDART00000169146
zgc:175135
chr24_-_14711597 4.03 ENSDART00000131830
junctophilin 1a
chr5_+_65157576 3.97 ENSDART00000159599
cilia and flagella associated protein 157
chr24_-_3477103 3.96 ENSDART00000143723
isopentenyl-diphosphate delta isomerase 1
chr11_+_18157260 3.84 ENSDART00000144659
zgc:173545
chr6_+_8315050 3.63 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr5_+_24287927 3.57 ENSDART00000143563
zinc finger, DHHC-type containing 23a
chr25_+_20089986 3.49 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr20_-_23171430 3.47 ENSDART00000109234
spermatogenesis associated 18
chr14_-_33454595 3.36 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr20_-_40755614 3.32 ENSDART00000061247
connexin 32.3
chr21_-_35325466 3.31 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ubiquitin-like domain containing CTD phosphatase 1
chr9_+_23009608 3.22 ENSDART00000079879
si:dkey-91i10.3
chr9_-_22821901 3.16 ENSDART00000101711
nebulin
chr13_+_30169681 3.11 ENSDART00000138326
phosphatase domain containing, paladin 1b
chr16_+_31511739 3.10 ENSDART00000049420
N-myc downstream regulated 1b
chr10_+_21780250 3.10 ENSDART00000183782
protocadherin 1 gamma 9
chr1_+_54908895 3.08 ENSDART00000145652
golgin A7 family, member Ba
chr25_-_7683316 3.04 ENSDART00000128820
si:ch211-286c4.6
chr25_-_10503043 3.03 ENSDART00000155404
cytochrome c oxidase subunit 8b
chr6_-_23931442 3.03 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr2_+_47623202 2.99 ENSDART00000154465
si:ch211-165b10.3
chr2_+_24304854 2.96 ENSDART00000078972
fat storage-inducing transmembrane protein 1
chr17_+_45737992 2.90 ENSDART00000135073
ENSDART00000143525
ENSDART00000158165
ENSDART00000184167
ENSDART00000109525
asparaginase homolog (S. cerevisiae)
chr1_-_25966068 2.87 ENSDART00000137869
ENSDART00000134192
synaptopodin 2b
chr4_-_10599062 2.80 ENSDART00000048003
tetraspanin 12
chr22_-_24757785 2.79 ENSDART00000078225
vitellogenin 5
chr3_+_60721342 2.77 ENSDART00000157772
forkhead box J1a
chr10_-_27046639 2.76 ENSDART00000041841
cornichon family AMPA receptor auxiliary protein 2
chr16_-_2818170 2.69 ENSDART00000081918
acyl-CoA thioesterase 22
chr18_+_36582815 2.64 ENSDART00000059311
sialic acid acetylesterase
chr21_+_9628854 2.63 ENSDART00000161753
ENSDART00000160711
mitogen-activated protein kinase 10
chr9_-_48397702 2.61 ENSDART00000147169
zgc:172182
chr15_-_14552101 2.61 ENSDART00000171169
numb homolog (Drosophila)-like
chr2_+_37140448 2.59 ENSDART00000045016
ENSDART00000142940
peroxisomal biogenesis factor 19
chr24_+_25692802 2.58 ENSDART00000190493
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr1_-_53750522 2.56 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr12_+_46605600 2.52 ENSDART00000123533
fatty acid desaturase 6
chr23_+_45785563 2.49 ENSDART00000186027

chr20_-_52846212 2.48 ENSDART00000040265
TBC1 domain family, member 7
chr16_-_28268201 2.46 ENSDART00000121671
ENSDART00000141911
si:dkey-12j5.1
chr15_-_1745408 2.43 ENSDART00000182311
syntaxin 1A (brain)
chr8_+_38415374 2.42 ENSDART00000085395
NK6 homeobox 3
chr10_-_36591511 2.41 ENSDART00000063347
solute carrier family 1 (glial high affinity glutamate transporter), member 3b
chr12_-_3756405 2.41 ENSDART00000150839
family with sequence similarity 57, member Bb
chr21_+_44857293 2.41 ENSDART00000134365
ENSDART00000168217
ENSDART00000065083
follistatin-like 4
chr15_+_1148074 2.40 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
myeloid leukemia factor 1
chr16_+_46995398 2.39 ENSDART00000177679
thrombospondin, type I, domain containing 7Ab
chr16_+_28881235 2.39 ENSDART00000146525
chromatin target of PRMT1b
chr1_-_25966411 2.38 ENSDART00000193375
synaptopodin 2b
chr4_-_16824231 2.37 ENSDART00000014007
glycogen synthase 2
chr2_+_20332044 2.31 ENSDART00000112131
phospholipid phosphatase related 4a
chr11_+_30057762 2.29 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr18_+_1145571 2.28 ENSDART00000135055
REC114 meiotic recombination protein
chr4_+_5848229 2.25 ENSDART00000161101
ENSDART00000067357
LYR motif containing 5a
chr2_+_22702488 2.21 ENSDART00000076647
kinesin family member 1Ab
chr5_+_28849155 2.20 ENSDART00000079090
zgc:174259
chr8_+_49778756 2.20 ENSDART00000083790
neurotrophic tyrosine kinase, receptor, type 2a
chr15_+_478524 2.19 ENSDART00000018062
si:ch1073-280e3.1
chr7_-_19420334 2.17 ENSDART00000173838
si:ch73-71d17.2
chr11_+_37178271 2.16 ENSDART00000161771
inter-alpha-trypsin inhibitor heavy chain 3b
chr3_-_50177658 2.14 ENSDART00000135309
zgc:114118
chr1_-_18811517 2.14 ENSDART00000142026
si:dkey-167i21.2
chr22_-_20695237 2.13 ENSDART00000112722
oogenesis-related gene
chr2_-_1443692 2.11 ENSDART00000004533
retinal pigment epithelium-specific protein 65a
chr23_+_45845159 2.11 ENSDART00000023944
lamin L3
chr5_+_28848870 2.11 ENSDART00000149563
zgc:174259
chr17_+_15433671 2.11 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr6_+_11249706 2.10 ENSDART00000186547
ENSDART00000193287
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr10_-_42882215 2.08 ENSDART00000180580
ENSDART00000187374

chr21_+_39197628 2.07 ENSDART00000113607
carboxypeptidase D, b
chr18_-_8313686 2.06 ENSDART00000182187
mitogen-activated protein kinase 8 interacting protein 2
chr11_-_4235811 2.03 ENSDART00000121716
si:ch211-236d3.4
chr7_+_58843700 2.03 ENSDART00000159500
ENSDART00000158436
lysophospholipase I
chr4_+_25607101 2.03 ENSDART00000133929
acyl-CoA thioesterase 14
chr2_-_47431205 2.00 ENSDART00000014350
ENSDART00000038828
paired box 3a
chr23_-_27345425 2.00 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr25_+_19106574 1.98 ENSDART00000067332
retinaldehyde binding protein 1b
chr9_+_40939336 1.98 ENSDART00000100386
myostatin b
chr17_+_15433518 1.95 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr12_+_48395693 1.95 ENSDART00000180362
stearoyl-CoA desaturase (delta-9-desaturase)
chr9_-_22822084 1.94 ENSDART00000142020
nebulin
chr21_+_45502621 1.93 ENSDART00000166719
si:dkey-223p19.2
chr25_+_3326885 1.91 ENSDART00000104866
lactate dehydrogenase Bb
chr24_-_10021341 1.89 ENSDART00000137250
zgc:173856
chr17_-_6399920 1.88 ENSDART00000022010
human immunodeficiency virus type I enhancer binding protein 2b
chr2_+_20331445 1.88 ENSDART00000186880
phospholipid phosphatase related 4a
chr24_-_6898302 1.87 ENSDART00000158646
dipeptidyl-peptidase 6a
chr13_-_21688176 1.87 ENSDART00000063825
shadow of prion protein
chr9_-_39005317 1.85 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr7_-_4036184 1.85 ENSDART00000019949
NDRG family member 2
chr7_-_4461104 1.85 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr6_+_11250316 1.84 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr21_+_21012210 1.83 ENSDART00000190317
nodal-related 1
chr21_+_45502773 1.81 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
chr16_+_23976227 1.80 ENSDART00000193013
apolipoprotein C-IV
chr17_-_6382392 1.80 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
taxilin beta b
chr1_+_29759678 1.80 ENSDART00000054059
ENSDART00000101856
carboxypeptidase B2 (plasma)
chr22_-_31060579 1.75 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr3_+_56366395 1.74 ENSDART00000154367
calcium channel, voltage-dependent, gamma subunit 5b
chr20_-_23041275 1.74 ENSDART00000188200

chr12_+_24561832 1.74 ENSDART00000088159
neurexin 1a
chr23_+_21424747 1.73 ENSDART00000135440
ENSDART00000104214
taste receptor, type 1, member 1
chr21_-_14803366 1.71 ENSDART00000190872
si:dkey-11o18.5
chr24_+_5912635 1.70 ENSDART00000153736
Pim proto-oncogene, serine/threonine kinase, related 63
chr19_-_45960191 1.69 ENSDART00000052434
ENSDART00000172732
eukaryotic translation initiation factor 3, subunit H, b
chr11_-_23332592 1.67 ENSDART00000125024
golgi transport 1A
chr2_+_9821757 1.67 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr3_-_35800221 1.67 ENSDART00000031390
CASK interacting protein 1
chr13_-_29421331 1.67 ENSDART00000150228
choline O-acetyltransferase a
chr16_-_52821023 1.67 ENSDART00000074718
spire-type actin nucleation factor 1b
chr12_+_16284086 1.66 ENSDART00000013360
ENSDART00000141169
protein phosphatase 1, regulatory subunit 3Cb
chr17_+_16429826 1.65 ENSDART00000136078
EF-hand calcium binding domain 11
chr15_-_21155641 1.65 ENSDART00000061098
ENSDART00000046443
si:dkey-105h12.2
chr3_+_17314997 1.63 ENSDART00000139763
signal transducer and activator of transcription 5a
chr12_-_17897134 1.63 ENSDART00000066407
neuronal pentraxin IIb
chr10_-_40484531 1.63 ENSDART00000142464
ENSDART00000180318
trace amine associated receptor 20z
chr21_+_6394929 1.62 ENSDART00000138600
si:ch211-225g23.1
chr6_+_11250033 1.61 ENSDART00000065411
ENSDART00000132677
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr16_+_22761846 1.61 ENSDART00000193028

chr2_+_33697340 1.60 ENSDART00000137669
si:dkey-31m5.3
chr15_-_47841259 1.60 ENSDART00000155384
kelch repeat and BTB (POZ) domain containing 3
chr11_+_20056732 1.60 ENSDART00000103997
FEZ family zinc finger 2
chr17_+_24318753 1.60 ENSDART00000064083
orthodenticle homeobox 1
chr20_-_1174266 1.59 ENSDART00000023304
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr19_-_5865766 1.58 ENSDART00000191007

chr17_-_40397752 1.58 ENSDART00000178483

chr12_+_34953038 1.58 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
QKI, KH domain containing, RNA binding 2
chr15_-_30857350 1.57 ENSDART00000138988
A kinase (PRKA) anchor protein 1b
chr17_-_1407593 1.57 ENSDART00000157622
ENSDART00000159458
zinc finger and BTB domain containing 42
chr18_-_6855991 1.56 ENSDART00000135206
protein phosphatase 6, regulatory subunit 2b
chr14_+_29581710 1.56 ENSDART00000188820
ENSDART00000193874
si:dkey-34l15.2
chr2_+_4894873 1.56 ENSDART00000164626
si:ch211-162e15.3
chr11_+_18175893 1.55 ENSDART00000177625
zgc:173545
chr8_-_25120231 1.55 ENSDART00000147308
adhesion molecule with Ig-like domain 1
chr11_+_41858807 1.54 ENSDART00000161605
intermediate filament family orphan 2b
chr12_+_28955766 1.54 ENSDART00000123417
ENSDART00000139347
zinc finger protein 668
chr21_+_22124736 1.54 ENSDART00000130179
ENSDART00000172573
cullin 5b
chr4_+_4267451 1.52 ENSDART00000192069
anoctamin 2
chr23_-_26652273 1.51 ENSDART00000112124
ENSDART00000111029
heparan sulfate proteoglycan 2
chr6_+_11369135 1.49 ENSDART00000151260
zgc:112416
chr15_+_45563656 1.48 ENSDART00000157501
claudin 15-like b
chr15_-_16121496 1.48 ENSDART00000128624
uncharacterized serine/threonine-protein kinase SgK494a
chr7_-_17416092 1.48 ENSDART00000043689
ENSDART00000170003
novel immune-type receptor 3a
novel immune-type receptor 3c
chr18_+_8937718 1.46 ENSDART00000138115
si:dkey-5i3.1
chr23_-_39784368 1.45 ENSDART00000110282
si:ch211-286f9.2
chr9_-_3866707 1.44 ENSDART00000010378
myosin IIIB
chr9_-_14273652 1.44 ENSDART00000135458
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr8_-_51293265 1.44 ENSDART00000127875
ENSDART00000181145
bone morphogenetic protein 1a
chr23_+_45845423 1.43 ENSDART00000183404
lamin L3
chr17_+_7524389 1.41 ENSDART00000067579
kelch-like family member 10b, tandem duplicate 2
chr24_-_5911973 1.41 ENSDART00000077933
ENSDART00000077922
Pim proto-oncogene, serine/threonine kinase, related 64
chr15_+_14856307 1.40 ENSDART00000167213
diablo, IAP-binding mitochondrial protein a
chr11_-_34628789 1.39 ENSDART00000192433
mitogen-activated protein kinase-activated protein kinase 3
chr14_-_2318590 1.38 ENSDART00000192735
protocadherin 2 alpha b 8
chr9_-_7394412 1.36 ENSDART00000145456
solute carrier family 23, member 3
chr8_+_41035230 1.36 ENSDART00000141349
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr23_+_26946744 1.34 ENSDART00000115141
calcium channel, voltage-dependent, beta 3b
chr11_-_1509773 1.34 ENSDART00000050762
phosphatase and actin regulator 3b
chr11_+_18183220 1.34 ENSDART00000113468

chr20_-_33566640 1.33 ENSDART00000159729
si:dkey-65b13.9
chr17_+_15111319 1.33 ENSDART00000185099

chr25_-_19433244 1.33 ENSDART00000154778
microtubule-associated protein 1Ab
chr11_-_37691449 1.32 ENSDART00000185340
zgc:158258
chr10_-_43392267 1.32 ENSDART00000142872
EGF-like repeats and discoidin I-like domains 3b
chr20_+_48739154 1.31 ENSDART00000100262
zgc:110348
chr1_+_22002649 1.30 ENSDART00000141317
dynein, axonemal, heavy chain 6
chr13_+_33462232 1.30 ENSDART00000177841
zgc:136302
chr20_-_8443425 1.30 ENSDART00000083908
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr16_-_13004166 1.29 ENSDART00000133735
calcium channel, voltage-dependent, gamma subunit 7b
chr7_-_24520866 1.29 ENSDART00000077039
fatty acid amide hydrolase 2b
chr24_-_33461313 1.27 ENSDART00000163706
si:ch73-173p19.2
chr23_+_33296588 1.27 ENSDART00000030368
si:ch211-226m16.3
chr9_+_29548630 1.27 ENSDART00000132295
ring finger protein 17
chr6_-_21678263 1.27 ENSDART00000038777
si:dkey-43k4.5
chr5_-_12407194 1.25 ENSDART00000125291
kinase suppressor of ras 2
chr25_-_17587785 1.25 ENSDART00000073679
ENSDART00000146851
zgc:66449
chr13_-_40316367 1.25 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2

Network of associatons between targets according to the STRING database.

First level regulatory network of hmx2_hmx3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0006145 purine nucleobase catabolic process(GO:0006145)
1.4 5.5 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
1.4 6.8 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.9 5.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.8 4.0 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.7 2.2 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.6 2.6 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.6 4.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.6 3.0 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.6 1.8 GO:0042730 fibrinolysis(GO:0042730)
0.6 4.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.6 1.7 GO:0010265 SCF complex assembly(GO:0010265)
0.6 5.6 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.6 1.7 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 2.2 GO:1901862 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.5 2.1 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.5 2.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.5 5.0 GO:0044805 late nucleophagy(GO:0044805)
0.5 2.4 GO:0003356 regulation of cilium beat frequency(GO:0003356) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.5 2.0 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.5 3.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 3.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.4 1.2 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.4 1.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.4 1.1 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.3 1.0 GO:0003403 optic vesicle formation(GO:0003403)
0.3 16.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 0.9 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.3 0.9 GO:0036076 ligamentous ossification(GO:0036076)
0.3 1.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.3 0.8 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 1.6 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3 1.6 GO:0021767 mammillary body development(GO:0021767)
0.3 1.0 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.3 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 2.8 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.2 1.2 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.2 1.0 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 1.4 GO:0032964 collagen biosynthetic process(GO:0032964)
0.2 6.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.2 0.7 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.2 0.9 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.7 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 5.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 7.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 2.5 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.2 0.8 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.2 1.2 GO:0032218 riboflavin transport(GO:0032218)
0.2 1.6 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 1.4 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.2 0.6 GO:0060137 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.2 1.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 3.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 2.1 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 1.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 0.9 GO:0051414 response to cortisol(GO:0051414)
0.2 1.3 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.2 0.7 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.2 3.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 1.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.2 6.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 2.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 2.0 GO:0050936 xanthophore differentiation(GO:0050936)
0.2 1.1 GO:0035627 ceramide transport(GO:0035627)
0.1 1.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.7 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.7 GO:0031650 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.4 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.1 1.0 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 2.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.5 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.8 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.8 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.8 GO:0035889 otolith tethering(GO:0035889)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.8 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 0.8 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 1.1 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 1.1 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.7 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 4.3 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 0.9 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 1.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 1.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 5.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 4.0 GO:0032355 response to estradiol(GO:0032355)
0.1 1.1 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 1.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.3 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 1.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.8 GO:0090311 regulation of protein deacetylation(GO:0090311)
0.1 0.8 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.0 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 1.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 3.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 1.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.8 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 2.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.0 GO:0007634 optokinetic behavior(GO:0007634)
0.1 0.4 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.6 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 1.3 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 1.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 2.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.9 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.6 GO:0097009 energy homeostasis(GO:0097009)
0.1 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.6 GO:0006833 water transport(GO:0006833)
0.1 1.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.5 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.5 GO:0030728 ovulation(GO:0030728)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 3.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 2.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 4.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 5.7 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 1.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.6 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 4.8 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 0.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 3.5 GO:0006119 oxidative phosphorylation(GO:0006119)
0.1 0.7 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.8 GO:0030324 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.1 0.9 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 12.6 GO:0060537 muscle tissue development(GO:0060537)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 1.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 3.9 GO:0048545 response to steroid hormone(GO:0048545)
0.1 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.7 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.1 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 1.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 4.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.1 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0002513 tolerance induction(GO:0002507) tolerance induction to self antigen(GO:0002513) thymocyte migration(GO:0072679)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.7 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0007632 visual behavior(GO:0007632)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.7 GO:0007413 axonal fasciculation(GO:0007413)
0.0 1.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0048942 myelination of lateral line nerve axons(GO:0048897) posterior lateral line nerve glial cell differentiation(GO:0048931) myelination of posterior lateral line nerve axons(GO:0048932) lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048938) posterior lateral line nerve glial cell development(GO:0048941) posterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048942)
0.0 2.9 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 2.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.3 GO:0097205 renal filtration(GO:0097205)
0.0 1.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.5 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 4.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.2 GO:1902305 regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 3.4 GO:0072376 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0 1.1 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.3 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.4 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.5 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.7 GO:0021591 ventricular system development(GO:0021591)
0.0 0.8 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.8 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.1 GO:0071696 ectodermal placode development(GO:0071696)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.9 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 6.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 1.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.4 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.7 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:0051180 vitamin transport(GO:0051180)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 3.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.6 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.0 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.7 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.7 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0015809 arginine transport(GO:0015809)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 0.6 GO:0051057 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.0 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 3.4 GO:0046777 protein autophosphorylation(GO:0046777)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0030314 junctional membrane complex(GO:0030314)
0.5 1.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 5.7 GO:0005869 dynactin complex(GO:0005869)
0.3 12.6 GO:0005861 troponin complex(GO:0005861)
0.2 0.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.2 GO:0000801 central element(GO:0000801)
0.2 2.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 3.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 5.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 1.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 1.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.4 GO:0001534 radial spoke(GO:0001534)
0.1 0.3 GO:0034464 BBSome(GO:0034464)
0.1 0.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 5.1 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 3.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.0 GO:0070069 cytochrome complex(GO:0070069)
0.1 2.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 4.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 4.8 GO:0016342 catenin complex(GO:0016342)
0.1 2.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.6 GO:0097546 ciliary base(GO:0097546)
0.1 6.8 GO:0030018 Z disc(GO:0030018)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 5.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.5 GO:0001650 fibrillar center(GO:0001650)
0.1 1.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0000938 GARP complex(GO:0000938)
0.1 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 5.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.3 GO:0005657 replication fork(GO:0005657)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 3.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.0 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.8 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.3 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 5.2 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.8 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0034703 cation channel complex(GO:0034703)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0031514 motile cilium(GO:0031514)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 2.7 GO:0043005 neuron projection(GO:0043005)
0.0 0.8 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.9 3.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.7 2.2 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.7 4.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.6 2.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.6 7.3 GO:0070697 activin receptor binding(GO:0070697)
0.5 2.1 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.5 2.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 2.6 GO:0008126 acetylesterase activity(GO:0008126)
0.4 2.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.4 2.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 2.8 GO:0045735 nutrient reservoir activity(GO:0045735)
0.4 1.1 GO:0004771 sterol esterase activity(GO:0004771)
0.4 2.9 GO:0004067 asparaginase activity(GO:0004067)
0.3 1.0 GO:0038046 enkephalin receptor activity(GO:0038046)
0.3 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.3 1.0 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.3 0.9 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.3 3.9 GO:0016405 CoA-ligase activity(GO:0016405)
0.3 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 0.9 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.3 1.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.3 1.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 1.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 0.8 GO:0070051 fibrinogen binding(GO:0070051)
0.3 4.1 GO:0005504 fatty acid binding(GO:0005504)
0.3 2.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 2.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 5.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 1.2 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.2 1.0 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.2 1.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.2 0.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 2.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 3.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 0.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 1.1 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.2 10.7 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.2 1.8 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 0.6 GO:0000035 acyl binding(GO:0000035)
0.2 1.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 0.6 GO:0004990 oxytocin receptor activity(GO:0004990)
0.2 4.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 2.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.4 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.7 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.2 2.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 0.7 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 1.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 2.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 3.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 2.1 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 3.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 1.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.7 GO:2001069 glycogen binding(GO:2001069)
0.1 0.4 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 1.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.1 GO:0070122 isopeptidase activity(GO:0070122)
0.1 7.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 4.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.3 GO:0051117 ATPase binding(GO:0051117)
0.1 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0035254 GKAP/Homer scaffold activity(GO:0030160) glutamate receptor binding(GO:0035254) ionotropic glutamate receptor binding(GO:0035255)
0.1 0.6 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.6 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.5 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 2.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 6.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 2.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.9 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.8 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 2.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 6.0 GO:0043130 ubiquitin binding(GO:0043130)
0.1 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 6.0 GO:0045296 cadherin binding(GO:0045296)
0.1 1.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 2.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.4 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 1.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 4.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.5 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 2.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 1.1 GO:0051427 hormone receptor binding(GO:0051427)
0.0 3.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.6 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 8.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.0 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 1.0 GO:0042562 hormone binding(GO:0042562)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 4.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.9 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 1.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.8 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 5.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 1.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.8 2.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5 5.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 2.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 2.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 3.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 7.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 4.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 4.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 0.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 1.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.2 4.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 1.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 5.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 0.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4