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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxb2a

Z-value: 0.74

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Transcription factors associated with hoxb2a

Gene Symbol Gene ID Gene Info
ENSDARG00000000175 homeobox B2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb2adr11_v1_chr3_+_23752150_237521500.372.4e-04Click!

Activity profile of hoxb2a motif

Sorted Z-values of hoxb2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_9462433 7.66 ENSDART00000152674
ENSDART00000040557
zgc:101840
chr9_+_38372216 7.05 ENSDART00000141895
phospholipase C, delta 4b
chr8_+_22930627 6.16 ENSDART00000187860
synaptophysin a
chr16_+_5774977 5.24 ENSDART00000134202
cholecystokinin a
chr23_-_26522760 5.05 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
chr18_+_17428258 4.84 ENSDART00000010452
zgc:91860
chr11_+_30057762 4.83 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr9_-_31278048 4.43 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr5_+_64732036 4.25 ENSDART00000073950
olfactomedin 1a
chr3_+_1637358 4.23 ENSDART00000180266

chr4_-_16833518 4.19 ENSDART00000179867
lactate dehydrogenase Ba
chr6_-_54826061 4.12 ENSDART00000149982
troponin I type 1b (skeletal, slow)
chr1_+_16397063 4.01 ENSDART00000159794
mitochondrial calcium uptake family, member 3a
chr17_+_23298928 3.96 ENSDART00000153652
zgc:165461
chr19_-_31402429 3.77 ENSDART00000137292
transmembrane protein 106Bb
chr19_+_14921000 3.63 ENSDART00000144052
opioid receptor, delta 1a
chr21_-_39177564 3.52 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr21_+_28958471 3.48 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_+_45365098 3.40 ENSDART00000052746
ENSDART00000156555
ubiquitin-conjugating enzyme E2Ia
chr22_-_20166660 3.31 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr23_-_14990865 3.27 ENSDART00000147799
ndrg family member 3b
chr13_+_15838151 3.26 ENSDART00000008987
kinesin light chain 1a
chr22_-_881080 3.25 ENSDART00000185489
choline/ethanolamine phosphotransferase 1b
chr1_-_10647484 3.25 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
chr14_+_24935131 3.22 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr22_+_1796057 3.22 ENSDART00000170834
zinc finger protein 1179
chr1_-_10647307 3.20 ENSDART00000103548
si:dkey-31e10.1
chr22_+_17205608 3.17 ENSDART00000181267
RAB3B, member RAS oncogene family
chr5_+_64732270 3.03 ENSDART00000134241
olfactomedin 1a
chr17_+_31185276 3.03 ENSDART00000062887
dispatched homolog 2 (Drosophila)
chr1_-_50859053 3.02 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
chr9_+_38983895 3.01 ENSDART00000144893
microtubule-associated protein 2
chr24_+_16547035 3.01 ENSDART00000164319
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_+_513986 2.99 ENSDART00000109083
ENSDART00000081945
thioredoxin-like 4B
chr16_-_29458806 2.97 ENSDART00000047931
leucine rich repeat and Ig domain containing 4b
chr20_-_46362606 2.91 ENSDART00000153087
BCL2 modifying factor 2
chr3_+_45364849 2.90 ENSDART00000153974
ubiquitin-conjugating enzyme E2Ia
chr7_+_30787903 2.87 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr25_+_16116740 2.87 ENSDART00000139778
fatty acyl CoA reductase 1
chr25_-_27722614 2.71 ENSDART00000190154
zgc:153935
chr9_-_32753535 2.70 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr5_-_41494831 2.64 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr1_+_34696503 2.60 ENSDART00000186106

chr20_+_27020201 2.57 ENSDART00000126919
ENSDART00000016014
chromogranin A
chr15_-_755023 2.56 ENSDART00000155594
zinc finger protein 1011
chr20_+_19512727 2.53 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr3_+_30922947 2.52 ENSDART00000184060
claudin i
chr17_-_28198099 2.51 ENSDART00000156143
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr15_-_9272328 2.51 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr24_+_17007407 2.51 ENSDART00000110652
zinc finger protein, X-linked
chr19_-_30524952 2.50 ENSDART00000103506
hippocalcin like 4
chr5_+_43965078 2.47 ENSDART00000113502
ENSDART00000187143
si:dkey-84j12.1
chr14_-_4273396 2.47 ENSDART00000127318
FERM and PDZ domain containing 1b
chr21_+_26726936 2.45 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr23_+_11285662 2.45 ENSDART00000111028
cell adhesion molecule L1-like a
chr15_-_44601331 2.44 ENSDART00000161514
zgc:165508
chr16_+_25011994 2.43 ENSDART00000157312
zinc finger protein 1035
chr2_+_33326522 2.42 ENSDART00000056655
Kruppel-like factor 17
chr1_+_40562540 2.42 ENSDART00000122059
short coiled-coil protein a
chr3_-_25814097 2.40 ENSDART00000169706
netrin 1b
chr16_+_13818743 2.39 ENSDART00000090191
folliculin
chr23_+_40460333 2.38 ENSDART00000184658
SOGA family member 3b
chr3_-_34337969 2.37 ENSDART00000151634
trinucleotide repeat containing 6C1
chr17_+_24722646 2.33 ENSDART00000138356
mitochondrial fission regulator 1-like
chr25_+_30298377 2.32 ENSDART00000153622
chromosome 11 open reading frame 96
chr12_+_23912074 2.30 ENSDART00000152864
supervillin a
chr16_+_7242610 2.29 ENSDART00000081477
sorcin
chr2_-_33687214 2.27 ENSDART00000147439
ATPase H+ transporting V0 subunit b
chr2_+_50608099 2.24 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr11_+_14937904 2.24 ENSDART00000185103

chr3_+_33341640 2.23 ENSDART00000186352
peptide YYa
chr20_-_38787341 2.22 ENSDART00000136771
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr1_+_16396870 2.22 ENSDART00000189245
ENSDART00000113266
mitochondrial calcium uptake family, member 3a
chr2_+_27010439 2.19 ENSDART00000030547
cadherin 7a
chr18_+_18000887 2.19 ENSDART00000147797
si:ch211-212o1.2
chr22_-_11137268 2.18 ENSDART00000178882
ATPase H+ transporting accessory protein 2
chr2_+_20332044 2.18 ENSDART00000112131
phospholipid phosphatase related 4a
chr13_-_40120252 2.17 ENSDART00000157852
cartilage acidic protein 1b
chr19_-_5103141 2.16 ENSDART00000150952
triosephosphate isomerase 1a
chr14_+_23717165 2.15 ENSDART00000006373
Nedd4 family interacting protein 1
chr10_-_34772211 2.13 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr15_+_6109861 2.12 ENSDART00000185154
Purkinje cell protein 4
chr14_+_30795559 2.10 ENSDART00000006132
cofilin 1
chr4_+_4849789 2.09 ENSDART00000130818
ENSDART00000127751
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr1_-_45039726 2.06 ENSDART00000186188
SMU1, DNA replication regulator and spliceosomal factor b
chr7_+_14291323 2.06 ENSDART00000053521
Rh family, C glycoprotein a
chr20_-_35040041 2.03 ENSDART00000131919
kinesin family member 26Bb
chr7_-_25895189 2.01 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr5_+_63302660 1.98 ENSDART00000142131
si:ch73-376l24.2
chr24_-_1341543 1.97 ENSDART00000169341
neuropilin 1a
chr17_-_25649079 1.97 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_-_32596394 1.94 ENSDART00000103239
tetraspanin 4b
chr3_+_34919810 1.93 ENSDART00000055264
carbonic anhydrase Xb
chr3_+_22442445 1.92 ENSDART00000190921
WNK lysine deficient protein kinase 4b
chr20_-_27225876 1.91 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
chr25_+_28825657 1.91 ENSDART00000153625
nuclear transcription factor Y, beta b
chr5_-_26765188 1.91 ENSDART00000029450
ring finger protein 181
chr25_+_35553542 1.91 ENSDART00000113723
Spi-1 proto-oncogene a
chr8_+_28452738 1.90 ENSDART00000062706
transmembrane protein 189
chr17_-_31695217 1.89 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr12_+_47162456 1.89 ENSDART00000186272
ENSDART00000180811
ryanodine receptor 2
chr8_-_46894362 1.88 ENSDART00000111124
acyl-CoA thioesterase 7
chr16_+_21330634 1.87 ENSDART00000191285
ENSDART00000183267
oxysterol binding protein-like 3b
chr20_-_45661049 1.86 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr7_+_7511914 1.85 ENSDART00000172848
chloride channel 3
chr25_-_27722309 1.84 ENSDART00000148121
zgc:153935
chr19_-_5805923 1.84 ENSDART00000134340
si:ch211-264f5.8
chr1_+_54865552 1.83 ENSDART00000145381
si:ch211-196h16.5
chr22_-_19552796 1.83 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr14_-_7137808 1.83 ENSDART00000054803
tRNA phosphotransferase 1
chr24_+_12989727 1.83 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr21_+_34088377 1.81 ENSDART00000170070
myotubularin related protein 1b
chr16_+_47207691 1.80 ENSDART00000062507
islet cell autoantigen 1
chr1_-_57280585 1.79 ENSDART00000152220
si:dkey-27j5.5
chr18_-_2433011 1.79 ENSDART00000181922
ENSDART00000193276

chr12_+_24342303 1.75 ENSDART00000111239
neurexin 1a
chr1_+_11977426 1.74 ENSDART00000103399
tetraspanin 5b
chr18_+_18000695 1.74 ENSDART00000146898
si:ch211-212o1.2
chr23_-_24493768 1.74 ENSDART00000135559
ENSDART00000046933
sulfotransferase family 1, cytosolic sulfotransferase 5
chr13_+_30903816 1.73 ENSDART00000191727
excision repair cross-complementation group 6
chr10_+_1849874 1.72 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr8_-_19216657 1.72 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
chr19_+_2631565 1.71 ENSDART00000171487
family with sequence similarity 126, member A
chr12_-_30500803 1.69 ENSDART00000153108
NHL repeat containing 2
chr23_-_36446307 1.69 ENSDART00000136623
zgc:174906
chr21_+_34088110 1.66 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
myotubularin related protein 1b
chr1_+_40023640 1.65 ENSDART00000101623
leucine-rich repeat LGI family, member 2b
chr17_+_24687338 1.65 ENSDART00000135794
selenoprotein N
chr21_-_44565236 1.64 ENSDART00000159323
fun14 domain containing 2
chr9_+_17983463 1.62 ENSDART00000182150
A kinase (PRKA) anchor protein 11
chr11_+_38280454 1.62 ENSDART00000171496
si:dkey-166c18.1
chr17_-_16422654 1.61 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr18_-_18875308 1.60 ENSDART00000127182
ADP-ribosylation factor-like 2 binding protein
chr13_-_45475289 1.58 ENSDART00000043345
arginine/serine-rich protein 1
chr10_-_4375190 1.57 ENSDART00000016102

chr1_+_55293424 1.57 ENSDART00000152464
zgc:172106
chr17_-_31639845 1.56 ENSDART00000154196
zinc finger protein 839
chr24_-_6078222 1.55 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr15_-_1844048 1.55 ENSDART00000102410
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr3_+_46459540 1.55 ENSDART00000188150
si:ch211-66e2.5
chr14_+_12178915 1.52 ENSDART00000054626
histone deacetylase 3
chr17_-_22324727 1.52 ENSDART00000160341

chr6_-_14292307 1.52 ENSDART00000177852
ENSDART00000061745
inositol polyphosphate-4-phosphatase type I Ab
chr7_+_71547747 1.51 ENSDART00000180869
adenylate cyclase activating polypeptide 1a
chr19_-_7495006 1.51 ENSDART00000148836
regulatory factor X, 5
chr12_-_3077395 1.50 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_+_54209504 1.48 ENSDART00000020033
X-ray repair complementing defective repair in Chinese hamster cells 1
chr7_-_72261721 1.47 ENSDART00000172229
RAS guanyl releasing protein 2
chr3_+_32832538 1.46 ENSDART00000139410
CD2 (cytoplasmic tail) binding protein 2
chr3_-_32169754 1.46 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr7_-_71389375 1.45 ENSDART00000128928

chr7_-_40145097 1.45 ENSDART00000173634
WD repeat domain 60
chr14_-_8271686 1.44 ENSDART00000165120
purine-rich element binding protein Ab
chr22_-_15593824 1.44 ENSDART00000123125
tropomyosin 4a
chr5_-_30615901 1.44 ENSDART00000147769
si:ch211-117m20.5
chr1_+_33647682 1.44 ENSDART00000114384
zinc finger protein 654
chr22_+_39096911 1.43 ENSDART00000157127
ENSDART00000153841
LIM and cysteine-rich domains 1
chr22_+_30496360 1.43 ENSDART00000189145

chr20_-_32270866 1.41 ENSDART00000153140
armadillo repeat containing 2
chr25_-_1235457 1.41 ENSDART00000093093
coronin, actin binding protein, 2Bb
chr19_+_366034 1.40 ENSDART00000093383
vacuolar protein sorting 72 homolog (S. cerevisiae)
chr18_-_29896367 1.40 ENSDART00000191303
C-x(9)-C motif containing 2
chr4_+_69559692 1.39 ENSDART00000164383
zinc finger protein 993
chr9_+_41156818 1.38 ENSDART00000105764
ENSDART00000147052
signal transducer and activator of transcription 4
chr22_+_2937485 1.38 ENSDART00000082222
ENSDART00000135507
ENSDART00000143258
centrosomal protein 19
chr7_-_7676186 1.37 ENSDART00000091105
microfibril associated protein 3 like
chr17_+_12658411 1.36 ENSDART00000139918
GPN-loop GTPase 1
chr24_+_39518774 1.34 ENSDART00000132939
defective in cullin neddylation 1 domain containing 3
chr8_+_23355484 1.34 ENSDART00000085361
ENSDART00000125729
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr6_-_41138854 1.33 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr22_-_881725 1.30 ENSDART00000035514
choline/ethanolamine phosphotransferase 1b
chr21_-_3770636 1.30 ENSDART00000053596
secretory carrier membrane protein 1
chr5_-_55933420 1.30 ENSDART00000050966
solute carrier family 25, member 46
chr11_-_18604542 1.30 ENSDART00000171183
zinc finger, MYND-type containing 8
chr8_-_37249991 1.29 ENSDART00000189275
ENSDART00000178556
RNA binding motif protein 39b
chr5_-_50640171 1.28 ENSDART00000183353
multiple C2 domains, transmembrane 1a
chr24_-_39518599 1.27 ENSDART00000145606
ENSDART00000031486
LYR motif containing 1
chr24_+_23716918 1.24 ENSDART00000080332
COP9 signalosome subunit 5
chr11_+_28476298 1.23 ENSDART00000122319
leucine rich repeat containing 38b
chr2_+_56213694 1.23 ENSDART00000162582
upf1 regulator of nonsense transcripts homolog (yeast)
chr16_+_9400661 1.23 ENSDART00000146174
KIAA0947-like (H. sapiens)
chr1_+_52929185 1.21 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr12_+_16087077 1.21 ENSDART00000141898
zinc finger protein 281b
chr6_-_40922971 1.21 ENSDART00000155363
SFI1 centrin binding protein
chr16_+_1353894 1.21 ENSDART00000148426
cugbp, Elav-like family member 3b
chr14_+_8940326 1.21 ENSDART00000159920
ribosomal protein S6 kinase a, like
chr17_-_21162821 1.20 ENSDART00000157283
abhydrolase domain containing 12
chr9_+_38163876 1.20 ENSDART00000137955
cytoplasmic linker associated protein 1a
chr10_-_21955231 1.19 ENSDART00000183695

chr5_-_16734060 1.19 ENSDART00000035859
ENSDART00000190457
ENSDART00000179244
ATPase family, AAA domain containing 1a
chr22_+_30543437 1.17 ENSDART00000137983
si:dkey-103k4.1
chr3_-_60827402 1.17 ENSDART00000053494
ankyrin repeat and sterile alpha motif domain containing 4B
chr4_-_193762 1.17 ENSDART00000169667
protein tyrosine phosphatase, receptor type, O
chr21_+_39365920 1.16 ENSDART00000140940
clustered mitochondria (cluA/CLU1) homolog b
chr15_+_7086327 1.15 ENSDART00000114560
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr6_-_43283122 1.15 ENSDART00000186022
FERM domain containing 4Ba
chr23_-_36418708 1.14 ENSDART00000132273
zinc finger protein 740b
chr10_-_41400049 1.14 ENSDART00000009838
glycerol-3-phosphate acyltransferase 4
chr24_+_32592748 1.14 ENSDART00000188256
si:ch211-282b22.1
chr20_-_38787047 1.14 ENSDART00000152913
ENSDART00000153430
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.9 3.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.9 2.6 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.8 7.3 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.8 2.4 GO:0048785 hatching gland development(GO:0048785)
0.8 2.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.7 2.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.7 2.7 GO:0021742 abducens nucleus development(GO:0021742)
0.6 4.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.6 2.5 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.6 3.1 GO:0000012 single strand break repair(GO:0000012)
0.5 2.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.5 2.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 1.9 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.4 1.7 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.4 3.3 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.4 2.0 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.4 1.9 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.4 4.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 6.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3 2.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 1.2 GO:0000338 protein deneddylation(GO:0000338)
0.3 1.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.3 0.8 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 2.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 1.7 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 1.2 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.2 1.2 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 1.7 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.2 3.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 0.7 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 3.8 GO:0032418 lysosome localization(GO:0032418)
0.2 0.6 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.2 0.8 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 1.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 1.0 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 1.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.8 GO:0015677 copper ion import(GO:0015677)
0.2 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 0.5 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2 1.9 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 1.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 0.5 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.2 0.6 GO:0030224 monocyte differentiation(GO:0030224)
0.2 2.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 2.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.9 GO:0036268 swimming(GO:0036268)
0.1 0.7 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 1.6 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.1 5.0 GO:0007586 digestion(GO:0007586)
0.1 2.2 GO:0060034 notochord cell differentiation(GO:0060034)
0.1 2.5 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 2.9 GO:0051014 actin filament severing(GO:0051014)
0.1 2.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 3.0 GO:0035195 gene silencing by miRNA(GO:0035195)
0.1 3.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 8.9 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 0.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 3.3 GO:0030073 insulin secretion(GO:0030073)
0.1 1.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 3.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 3.6 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 2.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 3.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.4 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.4 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.4 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 1.0 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.4 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.1 1.1 GO:0045471 response to ethanol(GO:0045471)
0.1 4.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.9 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 1.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 3.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.6 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 1.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.4 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.9 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 1.8 GO:0000266 mitochondrial fission(GO:0000266)
0.1 2.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 1.0 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.3 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 2.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 5.2 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 1.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 3.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 1.9 GO:0036269 swimming behavior(GO:0036269)
0.0 2.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.4 GO:0097696 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.7 GO:0031033 myosin filament organization(GO:0031033)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.9 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 2.5 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.2 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 1.2 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 2.4 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.6 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 2.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.0 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.3 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.6 GO:0010970 establishment of localization by movement along microtubule(GO:0010970)
0.0 1.2 GO:0006497 protein lipidation(GO:0006497)
0.0 2.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.3 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 6.4 GO:0008380 RNA splicing(GO:0008380)
0.0 1.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0015698 inorganic anion transport(GO:0015698)
0.0 0.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.7 GO:0006954 inflammatory response(GO:0006954)
0.0 0.9 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0007062 sister chromatid cohesion(GO:0007062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0005955 calcineurin complex(GO:0005955)
0.5 6.2 GO:1990246 uniplex complex(GO:1990246)
0.5 1.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4 2.2 GO:0070724 BMP receptor complex(GO:0070724)
0.4 1.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 3.3 GO:0045171 intercellular bridge(GO:0045171)
0.3 4.5 GO:0005682 U5 snRNP(GO:0005682)
0.3 2.6 GO:0042583 chromaffin granule(GO:0042583)
0.2 1.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 2.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 2.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 2.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0035060 brahma complex(GO:0035060)
0.1 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.1 7.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 2.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.9 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 7.9 GO:0008021 synaptic vesicle(GO:0008021)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 2.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 4.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 3.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 2.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 4.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.0 GO:0030496 midbody(GO:0030496)
0.0 3.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 7.3 GO:0045202 synapse(GO:0045202)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.4 GO:0005604 basement membrane(GO:0005604)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 2.7 GO:0016459 myosin complex(GO:0016459)
0.0 16.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0000922 spindle pole(GO:0000922)
0.0 1.8 GO:0005819 spindle(GO:0005819)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.4 GO:0005884 actin filament(GO:0005884)
0.0 2.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.6 GO:0010008 endosome membrane(GO:0010008)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 13.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0005912 adherens junction(GO:0005912)
0.0 0.8 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
1.2 3.6 GO:0038046 enkephalin receptor activity(GO:0038046)
0.9 4.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.6 3.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 2.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 3.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.5 1.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.4 2.2 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.4 2.2 GO:0050699 WW domain binding(GO:0050699)
0.4 2.9 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 2.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.4 1.5 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.4 1.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 3.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 0.9 GO:0019777 Atg12 transferase activity(GO:0019777)
0.3 1.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 5.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.3 1.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.3 0.8 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 1.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 1.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.0 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 0.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.6 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 6.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.2 2.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.5 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2 2.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 2.1 GO:0045503 dynein light chain binding(GO:0045503)
0.2 1.7 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 6.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0043531 ADP binding(GO:0043531)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 3.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.9 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 2.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.8 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 2.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 2.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.7 GO:0070628 proteasome binding(GO:0070628)
0.1 2.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 2.0 GO:0031267 small GTPase binding(GO:0031267)
0.1 2.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 2.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 1.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.6 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0060182 apelin receptor activity(GO:0060182)
0.1 2.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 2.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 2.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 3.9 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 2.4 GO:0019838 growth factor binding(GO:0019838)
0.0 2.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 8.4 GO:0003924 GTPase activity(GO:0003924)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.3 2.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 2.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 2.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 3.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 3.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 1.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.5 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.7 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis