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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxb6a+hoxb6b

Z-value: 6.59

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Transcription factors associated with hoxb6a+hoxb6b

Gene Symbol Gene ID Gene Info
ENSDARG00000010630 homeobox B6a
ENSDARG00000026513 homeobox B6b
ENSDARG00000111786 homeobox B6b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb6bdr11_v1_chr12_+_27127139_271271390.511.1e-07Click!
hoxb6adr11_v1_chr3_+_23703704_237037040.232.4e-02Click!

Activity profile of hoxb6a+hoxb6b motif

Sorted Z-values of hoxb6a+hoxb6b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_25916530 78.82 ENSDART00000186386
synuclein, gamma b (breast cancer-specific protein 1)
chr8_-_49431939 75.54 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
synaptophysin b
chr9_-_32753535 68.04 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr20_+_34915945 66.28 ENSDART00000153064
synaptosomal-associated protein, 25a
chr2_-_54387550 62.83 ENSDART00000097388
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr10_-_17745345 61.74 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
chr21_-_21373242 57.87 ENSDART00000079629
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr22_-_13851297 57.34 ENSDART00000080306
S100 calcium binding protein, beta (neural)
chr4_-_7212875 57.06 ENSDART00000161297
leucine rich repeat neuronal 3b
chr5_-_29643930 56.90 ENSDART00000161250
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr14_+_35748385 56.73 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
glutamate receptor, ionotropic, AMPA 2b
chr21_-_22114625 54.81 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr11_+_25735478 53.79 ENSDART00000103566
si:dkey-183j2.10
chr9_+_31282161 52.33 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr21_-_22115136 51.58 ENSDART00000134715
ENSDART00000089246
ENSDART00000139789
ELMO/CED-12 domain containing 1
chr24_-_6158933 50.73 ENSDART00000021609
glutamate decarboxylase 2
chr5_+_58372164 50.73 ENSDART00000057910
neurogranin (protein kinase C substrate, RC3) a
chr21_+_13861589 48.99 ENSDART00000015629
ENSDART00000171306
syntaxin binding protein 1a
chr22_+_18389271 47.99 ENSDART00000088270
YjeF N-terminal domain containing 3
chr14_+_35748206 47.63 ENSDART00000177391
glutamate receptor, ionotropic, AMPA 2b
chr16_-_16182319 47.48 ENSDART00000103815
stathmin 2a
chr23_-_11870962 47.42 ENSDART00000143481
si:dkey-178k16.1
chr9_-_44295071 47.35 ENSDART00000011837
neuronal differentiation 1
chr13_+_36764715 46.30 ENSDART00000111832
ENSDART00000085230
atlastin GTPase 1
chr4_+_5506952 46.06 ENSDART00000032857
ENSDART00000160222
mitogen-activated protein kinase 11
chr23_-_30431333 45.79 ENSDART00000146633
calmodulin binding transcription activator 1a
chr10_+_21804772 45.35 ENSDART00000162194
protocadherin 1 gamma 31
chr20_-_34801181 45.32 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr4_+_12615836 44.84 ENSDART00000003583
LIM domain only 3
chr15_+_43166511 44.64 ENSDART00000011737
flj13639
chr4_+_11375894 44.24 ENSDART00000190471
ENSDART00000143963
piccolo presynaptic cytomatrix protein a
chr14_+_34966598 44.06 ENSDART00000004550
ring finger protein 145a
chr9_-_54840124 44.01 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr20_-_25671342 43.91 ENSDART00000182775
si:dkeyp-117h8.2
chr21_-_42007213 43.82 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr13_+_11436130 43.67 ENSDART00000169895
zinc finger and BTB domain containing 18
chr15_-_44512461 43.57 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr17_-_16965809 43.30 ENSDART00000153697
neurexin 3a
chr8_+_31248917 43.04 ENSDART00000112170
un-named hu7912
chr1_-_14234076 42.76 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr17_-_26926577 42.64 ENSDART00000050202
regulator of calcineurin 3
chr12_+_24344963 42.01 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
neurexin 1a
chr14_+_35806605 41.91 ENSDART00000173093
glutamate receptor, ionotropic, AMPA 2b
chr2_+_31833997 41.76 ENSDART00000066788
ependymin related 1
chr14_-_36378494 41.75 ENSDART00000058503
glycoprotein M6Aa
chr19_-_9472893 41.55 ENSDART00000045565
ENSDART00000137505
vesicle-associated membrane protein 1
chr21_+_28958471 41.12 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr6_-_10320676 40.97 ENSDART00000151247
sodium channel, voltage-gated, type I like, alpha b
chr24_-_24849091 40.68 ENSDART00000133649
ENSDART00000038290
corticotropin releasing hormone b
chr13_+_27314795 40.59 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr8_+_31119548 40.36 ENSDART00000136578
synapsin I
chr1_+_25801648 39.98 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr5_+_64732036 39.96 ENSDART00000073950
olfactomedin 1a
chr2_+_34967022 39.60 ENSDART00000134926
astrotactin 1
chr10_-_22845485 39.51 ENSDART00000079454
vesicle-associated membrane protein 2
chr20_+_34717403 39.39 ENSDART00000034252
prepronociceptin b
chr7_-_49594995 39.17 ENSDART00000174161
ENSDART00000109147
BR serine/threonine kinase 2b
chr20_+_27020201 38.94 ENSDART00000126919
ENSDART00000016014
chromogranin A
chr5_-_23362602 38.82 ENSDART00000137120
glutamate receptor, ionotropic, AMPA 3a
chr12_-_10300101 38.71 ENSDART00000126428
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr24_-_15648636 38.42 ENSDART00000136200
cerebellin 2b precursor
chr23_+_20563779 38.37 ENSDART00000146008
CaM kinase-like vesicle-associated, like
chr25_-_13381854 38.36 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr16_+_37582872 38.33 ENSDART00000169331
adhesion G protein-coupled receptor B1a
chr17_-_12389259 38.31 ENSDART00000185724
synaptosomal-associated protein, 25b
chr22_-_11493236 38.18 ENSDART00000002691
tetraspanin 7b
chr8_-_34052019 38.17 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr18_-_38088099 37.78 ENSDART00000146120
leucine zipper protein 2
chr6_+_3828560 37.30 ENSDART00000185273
ENSDART00000179091
glutamate decarboxylase 1b
chr24_-_33756003 37.10 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr15_-_24869826 37.08 ENSDART00000127047
tumor suppressor candidate 5a
chr15_+_22267847 37.05 ENSDART00000110665
sperm autoantigenic protein 17
chr16_-_12173554 36.97 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr11_+_35364445 36.87 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr5_-_23280098 36.80 ENSDART00000126540
ENSDART00000051533
proteolipid protein 1b
chr7_-_45076131 36.66 ENSDART00000110590
zgc:194678
chr3_-_28665291 36.46 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr7_+_25059845 36.45 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr21_+_22630297 36.44 ENSDART00000147175
si:dkeyp-69c1.7
chr19_+_10396042 36.19 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr24_+_2519761 35.82 ENSDART00000106619
neuritin 1a
chr13_+_27951688 35.68 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr13_-_29420885 35.63 ENSDART00000024225
choline O-acetyltransferase a
chr16_-_26074529 35.56 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr10_+_21576909 35.26 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr25_-_32869794 35.23 ENSDART00000162784
transmembrane protein 266
chr6_-_41229787 35.18 ENSDART00000065013
synaptoporin
chr14_-_32258759 35.13 ENSDART00000052949
fibroblast growth factor 13a
chr20_-_45661049 35.06 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr3_+_54047342 34.92 ENSDART00000178486
olfactomedin 2a
chr8_-_14052349 34.42 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr17_+_33495194 34.40 ENSDART00000033691
parathyroid hormone 2
chr20_-_29474859 34.31 ENSDART00000152906
ENSDART00000045249
secretogranin V
chr15_-_12545683 34.29 ENSDART00000162807
sodium channel, voltage-gated, type II, beta
chr7_-_35708450 33.98 ENSDART00000193886
iroquois homeobox 5a
chr7_-_31932723 33.90 ENSDART00000014843
brain-derived neurotrophic factor
chr3_-_18711288 33.89 ENSDART00000183885
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr7_-_52842605 33.86 ENSDART00000083002
microtubule-associated protein 1Aa
chr17_-_37214196 33.79 ENSDART00000128715
kinesin family member 3Cb
chr8_+_47633438 33.71 ENSDART00000139096
si:ch211-251b21.1
chr14_-_18672561 33.68 ENSDART00000166730
ENSDART00000006998
SLIT and NTRK-like family, member 4
chr20_+_30490682 33.67 ENSDART00000184871
myelin transcription factor 1-like, a
chr6_-_35472923 33.43 ENSDART00000185907
regulator of G protein signaling 8
chr16_-_25519762 33.35 ENSDART00000146479
ENSDART00000142062
dystrobrevin binding protein 1a
chr19_+_24882845 33.32 ENSDART00000010580
si:ch211-195b13.1
chr7_+_30787903 33.30 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr23_+_28693278 33.24 ENSDART00000078148
structural maintenance of chromosomes 1A
chr16_+_46111849 32.87 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr14_-_49063157 32.87 ENSDART00000021260
septin 8b
chr6_+_24817852 32.79 ENSDART00000165609
BarH-like homeobox 2
chr6_+_29860776 32.57 ENSDART00000028406
discs, large homolog 1 (Drosophila)
chr15_-_27710513 32.33 ENSDART00000005641
ENSDART00000134373
LIM homeobox 1a
chr12_+_18681477 32.25 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr11_+_39672874 32.14 ENSDART00000046663
ENSDART00000157659
calmodulin binding transcription activator 1b
chr17_-_36936649 32.11 ENSDART00000145236
dihydropyrimidinase-like 5a
chr17_+_5915875 32.11 ENSDART00000184179
fibronectin type III domain containing 4b
chr7_-_28148310 32.10 ENSDART00000044208
LIM domain only 1
chr24_-_8730913 31.97 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
transcription factor AP-2 alpha
chr1_+_45085194 31.91 ENSDART00000193863
si:ch211-151p13.8
chr13_+_11440389 31.91 ENSDART00000186463
zinc finger and BTB domain containing 18
chr14_+_44545092 31.82 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr10_+_15777258 31.79 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr10_+_21650828 31.75 ENSDART00000160754
protocadherin 1 gamma 1
chr8_+_16025554 31.63 ENSDART00000110171
ELAV like neuron-specific RNA binding protein 4
chr21_-_42007482 31.55 ENSDART00000075740
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_-_26782573 31.54 ENSDART00000090611
SH3 domain containing GRB2 like 2a, endophilin A1
chr18_-_8313686 31.52 ENSDART00000182187
mitogen-activated protein kinase 8 interacting protein 2
chr1_+_16397063 31.49 ENSDART00000159794
mitochondrial calcium uptake family, member 3a
chr21_-_27010796 31.43 ENSDART00000065398
ENSDART00000144342
ENSDART00000126542
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr2_+_34967210 31.34 ENSDART00000141796
astrotactin 1
chr17_-_37156520 31.34 ENSDART00000145669
dystrobrevin, beta b
chr24_-_7699356 31.16 ENSDART00000013117
synaptotagmin Vb
chr7_+_61050329 31.16 ENSDART00000115355
NACHT and WD repeat domain containing 2
chr1_-_56223913 31.14 ENSDART00000019573
zgc:65894
chr22_+_5103349 31.00 ENSDART00000083474
ataxia, cerebellar, Cayman type a
chr4_-_5302866 30.98 ENSDART00000138590
si:ch211-214j24.9
chr10_+_29698467 30.92 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr3_+_29714775 30.90 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr8_+_22582146 30.66 ENSDART00000157655
ENSDART00000189892

chr20_-_20821783 30.66 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
creatine kinase, brain b
chr25_+_7670683 30.64 ENSDART00000040275
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr12_+_5081759 30.51 ENSDART00000164178
proline-rich transmembrane protein 2
chr10_+_21563986 30.37 ENSDART00000100600
protocadherin 1 alpha 6
chr19_-_31522625 30.37 ENSDART00000158438
ENSDART00000035049
N-terminal EF-hand calcium binding protein 1
chr3_-_28075756 30.13 ENSDART00000122037
RNA binding fox-1 homolog 1
chr15_+_36115955 30.01 ENSDART00000032702
somatostatin 1, tandem duplicate 2
chr9_+_44430974 29.97 ENSDART00000056846
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_-_46398584 29.82 ENSDART00000193098
calcium/calmodulin-dependent protein kinase Ia
chr21_-_43949208 29.67 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr14_-_43000836 29.63 ENSDART00000162714
protocadherin 10b
chr1_-_22412042 29.60 ENSDART00000074678
cholinergic receptor, nicotinic, beta polypeptide 3a
chr13_+_38430466 29.52 ENSDART00000132691
adhesion G protein-coupled receptor B3
chr20_-_28800999 29.30 ENSDART00000049462
RAB15, member RAS oncogene family
chr13_+_16522608 29.11 ENSDART00000182838
ENSDART00000143200
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr17_+_31185276 29.08 ENSDART00000062887
dispatched homolog 2 (Drosophila)
chr1_+_25783801 28.92 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr14_-_34044369 28.79 ENSDART00000149396
ENSDART00000123607
ENSDART00000190746
cytoplasmic FMR1 interacting protein 2
chr3_-_32320537 28.77 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr19_+_14921000 28.75 ENSDART00000144052
opioid receptor, delta 1a
chr6_-_38419318 28.73 ENSDART00000138026
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr4_-_193762 28.69 ENSDART00000169667
protein tyrosine phosphatase, receptor type, O
chr1_+_34203817 28.60 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr6_-_24358732 28.46 ENSDART00000159595
epoxide hydrolase 4
chr1_-_23557877 28.45 ENSDART00000145942
family with sequence similarity 184, member B
chr17_-_45552602 28.45 ENSDART00000154844
ENSDART00000034432
sushi domain containing 4
chr21_-_39639954 28.44 ENSDART00000026766
aldolase C, fructose-bisphosphate, b
chr4_+_17279966 28.37 ENSDART00000067005
ENSDART00000137487
branched chain amino-acid transaminase 1, cytosolic
chr23_-_29667716 28.35 ENSDART00000158302
ENSDART00000133902
calsyntenin 1
chr3_-_28120092 28.34 ENSDART00000151143
RNA binding fox-1 homolog 1
chr17_-_22010668 28.31 ENSDART00000031998
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr10_-_24371312 28.31 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr1_-_38815361 28.23 ENSDART00000148790
ENSDART00000148572
ENSDART00000149080
ankyrin repeat and SOCS box containing 5b
chr1_+_40023640 28.22 ENSDART00000101623
leucine-rich repeat LGI family, member 2b
chr2_+_24199276 28.19 ENSDART00000140575
microtubule associated protein 4 like
chr14_-_34276574 28.02 ENSDART00000021437
glutamate receptor, ionotropic, AMPA 1a
chr5_-_32323136 27.86 ENSDART00000110804
heat shock protein, alpha-crystallin-related, b15
chr1_+_11977426 27.85 ENSDART00000103399
tetraspanin 5b
chr5_-_3627110 27.71 ENSDART00000156071
si:zfos-375h5.1
chr20_-_10120442 27.67 ENSDART00000144970
Meis homeobox 2b
chr23_-_14918276 27.64 ENSDART00000179831
ndrg family member 3b
chr9_-_1702648 27.63 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr13_+_7292061 27.54 ENSDART00000179504
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr19_-_32641725 27.40 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr3_+_46628885 27.33 ENSDART00000006602
phosphodiesterase 4A, cAMP-specific
chr24_+_14713776 27.33 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr1_+_7679328 27.14 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr2_+_24199073 27.12 ENSDART00000144110
microtubule associated protein 4 like
chr23_-_29505463 27.10 ENSDART00000050915
kinesin family member 1B
chr21_-_30545121 27.10 ENSDART00000019199
RAB39B, member RAS oncogene family a
chr13_-_33000649 27.08 ENSDART00000133677
RNA binding motif protein 25a
chr16_-_20435475 27.00 ENSDART00000139776
chimerin 2
chr20_+_16743056 26.99 ENSDART00000050308
calmodulin 1b
chr19_-_17658160 26.88 ENSDART00000151766
ENSDART00000170790
ENSDART00000186678
ENSDART00000188045
ENSDART00000176980
ENSDART00000166313
ENSDART00000188589
thyroid hormone receptor beta
chr14_-_33872092 26.77 ENSDART00000111903
si:ch73-335m24.2
chr10_+_21588002 26.63 ENSDART00000100596
protocadherin 1 alpha 6
chr10_+_21559605 26.58 ENSDART00000123648
ENSDART00000108584
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr20_-_26042070 26.53 ENSDART00000140255
si:dkey-12h9.6
chr16_+_32059785 26.50 ENSDART00000134459
si:dkey-40m6.8
chr12_+_24344611 26.18 ENSDART00000093094
neurexin 1a
chr14_-_2264494 25.90 ENSDART00000191149
protocadherin 2 alpha b 9

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb6a+hoxb6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
29.3 88.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
24.4 121.8 GO:0070208 protein heterotrimerization(GO:0070208)
17.0 68.0 GO:0021742 abducens nucleus development(GO:0021742)
16.3 146.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
16.2 32.3 GO:0061213 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
14.7 44.0 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
14.6 43.9 GO:0048917 posterior lateral line ganglion development(GO:0048917)
14.4 143.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
13.7 41.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
13.6 40.7 GO:0035902 response to immobilization stress(GO:0035902)
13.5 53.8 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
13.0 38.9 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
12.3 37.0 GO:0021611 facial nerve formation(GO:0021611)
12.0 48.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
11.9 35.6 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
11.4 45.5 GO:0009098 leucine biosynthetic process(GO:0009098)
11.1 55.3 GO:0016322 neuron remodeling(GO:0016322)
10.9 43.6 GO:0060074 synapse maturation(GO:0060074)
10.2 10.2 GO:0032652 interleukin-1 production(GO:0032612) regulation of interleukin-1 production(GO:0032652)
10.0 40.0 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
9.5 28.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
8.8 35.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
8.4 33.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
8.3 50.0 GO:0021767 mammillary body development(GO:0021767)
8.3 24.8 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
8.2 8.2 GO:0060031 mediolateral intercalation(GO:0060031)
8.2 32.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
8.1 24.2 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
7.6 22.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
7.5 15.0 GO:0001692 histamine metabolic process(GO:0001692)
7.5 52.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
7.3 132.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
7.1 21.3 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
6.9 34.3 GO:0061072 iris morphogenesis(GO:0061072)
6.7 20.2 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
6.3 143.9 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
6.0 24.2 GO:0003322 pancreatic A cell development(GO:0003322)
6.0 18.1 GO:0046069 cGMP catabolic process(GO:0046069)
5.9 11.8 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
5.8 52.4 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
5.7 23.0 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
5.7 11.5 GO:0051196 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
5.7 102.1 GO:0072160 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
5.7 17.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
5.5 149.1 GO:0016082 synaptic vesicle priming(GO:0016082)
5.4 32.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
5.3 63.9 GO:0035094 response to nicotine(GO:0035094)
5.1 15.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
5.1 15.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
4.9 34.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
4.8 67.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
4.8 38.5 GO:0021794 thalamus development(GO:0021794)
4.8 24.0 GO:0023041 neuronal signal transduction(GO:0023041)
4.8 14.4 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858)
4.8 71.8 GO:0035493 SNARE complex assembly(GO:0035493)
4.5 13.5 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
4.5 13.4 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
4.5 71.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
4.4 40.0 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
4.4 35.5 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
4.4 39.9 GO:0045920 negative regulation of exocytosis(GO:0045920)
4.4 79.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
4.4 13.2 GO:0060986 regulation of endocrine process(GO:0044060) endocrine hormone secretion(GO:0060986)
4.4 79.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
4.4 43.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
4.3 30.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
4.3 17.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
4.3 13.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
4.3 30.0 GO:0061635 regulation of protein complex stability(GO:0061635)
4.3 17.1 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
4.1 53.5 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
4.1 12.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
4.0 16.0 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
4.0 23.9 GO:0003232 bulbus arteriosus development(GO:0003232)
4.0 31.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
4.0 43.8 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
4.0 71.4 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
3.9 74.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
3.8 15.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
3.8 26.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
3.8 26.7 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
3.7 29.7 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
3.7 44.4 GO:0031338 regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
3.7 25.9 GO:0010996 response to auditory stimulus(GO:0010996)
3.7 59.1 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
3.6 17.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
3.5 170.2 GO:0007019 microtubule depolymerization(GO:0007019)
3.5 28.2 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
3.4 82.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
3.4 16.8 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
3.3 23.4 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
3.3 36.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
3.3 13.3 GO:0010226 response to lithium ion(GO:0010226)
3.3 26.6 GO:0046958 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
3.3 26.4 GO:0090594 inflammatory response to wounding(GO:0090594)
3.3 13.0 GO:0061549 sympathetic ganglion development(GO:0061549)
3.2 13.0 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
3.2 38.9 GO:0045773 positive regulation of axon extension(GO:0045773)
3.2 16.2 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
3.2 109.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
3.2 19.4 GO:0014015 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
3.2 28.5 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
3.2 9.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
3.1 12.5 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
3.1 12.5 GO:0015677 copper ion import(GO:0015677)
3.1 25.0 GO:0072498 embryonic skeletal joint development(GO:0072498)
3.1 49.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
3.1 43.0 GO:0046883 regulation of hormone secretion(GO:0046883)
3.1 9.2 GO:0019695 choline metabolic process(GO:0019695)
3.0 15.1 GO:0060055 endothelial cell chemotaxis(GO:0035767) angiogenesis involved in wound healing(GO:0060055)
3.0 9.0 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
3.0 75.0 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
3.0 15.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
3.0 11.8 GO:0019532 oxalate transport(GO:0019532)
3.0 20.7 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
2.9 20.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
2.9 20.6 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
2.9 8.7 GO:0046113 nucleobase catabolic process(GO:0046113)
2.9 99.9 GO:0050708 regulation of protein secretion(GO:0050708)
2.8 5.6 GO:0048588 developmental cell growth(GO:0048588)
2.8 56.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
2.8 8.4 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
2.8 25.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
2.8 22.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
2.7 13.6 GO:0014896 muscle hypertrophy(GO:0014896)
2.7 16.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
2.7 8.1 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
2.7 29.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
2.7 5.4 GO:0033337 dorsal fin development(GO:0033337)
2.7 13.5 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
2.7 8.0 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
2.6 7.9 GO:0003403 optic vesicle formation(GO:0003403)
2.6 15.8 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
2.6 39.4 GO:0042670 retinal cone cell differentiation(GO:0042670)
2.6 7.8 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
2.6 10.3 GO:0051012 microtubule sliding(GO:0051012)
2.6 25.7 GO:0044805 late nucleophagy(GO:0044805)
2.6 7.7 GO:0060292 long term synaptic depression(GO:0060292)
2.6 23.0 GO:0001964 startle response(GO:0001964)
2.6 20.4 GO:0006895 Golgi to endosome transport(GO:0006895)
2.5 53.5 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.5 20.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
2.5 12.6 GO:0007624 ultradian rhythm(GO:0007624)
2.5 9.9 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
2.5 19.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
2.5 27.0 GO:0016199 axon midline choice point recognition(GO:0016199)
2.4 24.0 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
2.4 43.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
2.4 7.2 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
2.4 19.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
2.4 47.2 GO:0097061 dendritic spine organization(GO:0097061)
2.3 155.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
2.3 57.6 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
2.3 11.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
2.3 211.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
2.3 22.9 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
2.3 27.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
2.3 15.8 GO:1990504 dense core granule exocytosis(GO:1990504)
2.2 15.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.2 17.9 GO:2000272 negative regulation of receptor activity(GO:2000272)
2.2 24.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
2.2 13.3 GO:0048795 swim bladder morphogenesis(GO:0048795)
2.2 28.8 GO:0097120 receptor localization to synapse(GO:0097120)
2.2 17.6 GO:0035264 multicellular organism growth(GO:0035264)
2.2 41.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
2.2 10.8 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.1 32.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
2.1 23.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
2.1 10.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
2.1 21.0 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
2.1 6.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
2.0 6.1 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
2.0 18.0 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
2.0 69.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
2.0 9.9 GO:0022029 forebrain cell migration(GO:0021885) telencephalon cell migration(GO:0022029)
2.0 5.9 GO:1902534 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
2.0 33.5 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
2.0 7.8 GO:0048339 paraxial mesoderm development(GO:0048339)
2.0 15.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
2.0 462.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.9 7.8 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
1.9 17.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.9 11.4 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
1.9 33.9 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.9 11.3 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
1.9 22.3 GO:0042407 cristae formation(GO:0042407)
1.8 7.4 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
1.8 5.5 GO:0035973 aggrephagy(GO:0035973)
1.8 7.4 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
1.8 12.8 GO:0021871 forebrain regionalization(GO:0021871)
1.8 51.1 GO:0070831 basement membrane assembly(GO:0070831)
1.8 5.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.8 17.7 GO:0048935 peripheral nervous system neuron development(GO:0048935)
1.8 12.3 GO:0042311 vasodilation(GO:0042311)
1.7 10.5 GO:1990108 protein linear deubiquitination(GO:1990108)
1.7 8.7 GO:0055016 hypochord development(GO:0055016)
1.7 13.8 GO:0046323 glucose import(GO:0046323)
1.7 17.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.7 12.0 GO:0036268 swimming(GO:0036268)
1.7 17.0 GO:0046548 retinal rod cell development(GO:0046548)
1.7 8.5 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.7 23.3 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
1.7 26.5 GO:0008053 mitochondrial fusion(GO:0008053)
1.7 33.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
1.6 26.4 GO:0036065 fucosylation(GO:0036065)
1.6 21.4 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
1.6 4.9 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
1.6 11.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
1.6 19.3 GO:0017121 phospholipid scrambling(GO:0017121)
1.6 38.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
1.6 31.4 GO:0006198 cAMP catabolic process(GO:0006198)
1.6 31.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
1.5 12.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.5 10.6 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
1.5 22.7 GO:0045116 protein neddylation(GO:0045116)
1.5 10.4 GO:0099560 synaptic membrane adhesion(GO:0099560)
1.5 5.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
1.5 39.4 GO:0048263 determination of dorsal identity(GO:0048263)
1.5 55.3 GO:0032400 melanosome localization(GO:0032400)
1.5 8.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
1.4 11.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.4 22.7 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
1.4 19.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.4 2.8 GO:0048211 Golgi vesicle docking(GO:0048211)
1.4 22.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
1.4 6.9 GO:0030431 sleep(GO:0030431)
1.4 9.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.4 2.7 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
1.4 5.5 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
1.4 40.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.3 5.3 GO:0050955 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
1.3 18.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
1.3 8.0 GO:0071569 protein ufmylation(GO:0071569)
1.3 26.3 GO:0033344 cholesterol efflux(GO:0033344)
1.3 9.2 GO:0007288 sperm axoneme assembly(GO:0007288)
1.3 17.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
1.3 7.7 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
1.3 16.6 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
1.3 6.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
1.3 3.8 GO:0008344 adult locomotory behavior(GO:0008344)
1.3 3.8 GO:0003404 optic vesicle morphogenesis(GO:0003404)
1.3 7.6 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
1.3 7.6 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
1.3 3.8 GO:0000338 protein deneddylation(GO:0000338)
1.2 8.7 GO:0007634 optokinetic behavior(GO:0007634)
1.2 11.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
1.2 4.9 GO:0032790 ribosome disassembly(GO:0032790)
1.2 20.6 GO:0015693 magnesium ion transport(GO:0015693)
1.2 23.1 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
1.2 21.7 GO:0019228 neuronal action potential(GO:0019228)
1.2 6.0 GO:0046485 ether lipid metabolic process(GO:0046485)
1.2 13.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
1.2 4.8 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
1.2 3.5 GO:0018872 arsonoacetate metabolic process(GO:0018872)
1.2 18.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
1.2 3.5 GO:0001779 natural killer cell differentiation(GO:0001779)
1.2 31.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
1.1 8.0 GO:1902093 positive regulation of sperm motility(GO:1902093)
1.1 9.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
1.1 7.9 GO:0018344 protein geranylgeranylation(GO:0018344)
1.1 15.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
1.1 5.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
1.1 13.4 GO:0039020 pronephric nephron tubule development(GO:0039020)
1.1 28.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
1.1 40.4 GO:0036269 swimming behavior(GO:0036269)
1.1 27.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
1.1 23.8 GO:0030032 lamellipodium assembly(GO:0030032)
1.1 15.1 GO:0036158 outer dynein arm assembly(GO:0036158)
1.1 2.2 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
1.1 21.3 GO:0015872 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) dopamine transport(GO:0015872)
1.1 3.2 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
1.0 42.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
1.0 245.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
1.0 4.1 GO:0061709 reticulophagy(GO:0061709)
1.0 288.5 GO:0099536 synaptic signaling(GO:0099536)
1.0 8.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.0 15.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
1.0 8.9 GO:1902547 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
1.0 20.7 GO:0007020 microtubule nucleation(GO:0007020)
1.0 7.9 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation involved in immune response(GO:0033006) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
1.0 8.8 GO:0002690 mast cell chemotaxis(GO:0002551) positive regulation of leukocyte chemotaxis(GO:0002690) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
1.0 2.9 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of sulfur metabolic process(GO:0042762) regulation of homocysteine metabolic process(GO:0050666)
1.0 34.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.0 5.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
1.0 27.8 GO:0021587 cerebellum morphogenesis(GO:0021587)
1.0 3.8 GO:0048321 axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
1.0 8.6 GO:0006465 signal peptide processing(GO:0006465)
0.9 4.7 GO:0032418 lysosome localization(GO:0032418)
0.9 14.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.9 8.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.9 3.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.9 6.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.9 4.6 GO:0010586 miRNA metabolic process(GO:0010586)
0.9 20.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.9 2.8 GO:0048569 post-embryonic organ development(GO:0048569)
0.9 8.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.9 33.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.9 2.7 GO:0061462 protein localization to lysosome(GO:0061462)
0.9 4.5 GO:0030242 pexophagy(GO:0030242)
0.9 4.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.9 9.9 GO:0021592 fourth ventricle development(GO:0021592)
0.9 2.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 2.7 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.9 6.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.9 19.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.9 6.2 GO:0097009 energy homeostasis(GO:0097009)
0.9 13.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.9 12.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.9 7.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.9 31.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.9 457.5 GO:0031175 neuron projection development(GO:0031175)
0.8 11.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.8 62.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.8 6.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.8 8.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.8 7.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.8 24.8 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.8 3.3 GO:0014909 smooth muscle cell migration(GO:0014909)
0.8 10.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.8 42.1 GO:0015914 phospholipid transport(GO:0015914)
0.8 23.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.8 2.4 GO:0060765 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.8 9.6 GO:0006020 inositol metabolic process(GO:0006020)
0.8 16.8 GO:1901214 regulation of neuron death(GO:1901214)
0.8 3.9 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.8 3.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.8 15.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 7.7 GO:0006868 glutamine transport(GO:0006868)
0.8 6.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.8 9.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.8 5.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.8 3.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.8 1.5 GO:0071042 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.7 37.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.7 3.7 GO:0046850 regulation of bone remodeling(GO:0046850)
0.7 31.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.7 13.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.7 8.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.7 3.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.7 7.3 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.7 3.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.7 58.0 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.7 3.6 GO:0000012 single strand break repair(GO:0000012)
0.7 31.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.7 11.8 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.7 15.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.7 114.6 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.7 6.1 GO:0070475 rRNA base methylation(GO:0070475)
0.6 8.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.6 11.0 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.6 2.6 GO:0001839 neural plate morphogenesis(GO:0001839)
0.6 1.9 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.6 4.4 GO:0016540 protein autoprocessing(GO:0016540)
0.6 6.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.6 53.3 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.6 12.5 GO:0032456 endocytic recycling(GO:0032456)
0.6 16.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.6 4.3 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.6 9.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.6 14.9 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.6 2.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.6 7.3 GO:0000154 rRNA modification(GO:0000154)
0.6 8.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.6 12.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.6 2.4 GO:0035521 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6 12.0 GO:0048634 regulation of muscle organ development(GO:0048634)
0.6 16.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.6 7.2 GO:0031057 negative regulation of histone modification(GO:0031057)
0.6 2.4 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.6 2.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.6 29.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.6 7.7 GO:0048854 brain morphogenesis(GO:0048854)
0.6 2.4 GO:0051645 Golgi localization(GO:0051645)
0.6 4.7 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.6 7.1 GO:0009648 photoperiodism(GO:0009648)
0.6 6.4 GO:0046683 response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.6 4.6 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.6 59.9 GO:0051260 protein homooligomerization(GO:0051260)
0.6 10.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 11.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.6 10.8 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.6 9.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.6 2.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 7.1 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.5 2.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.5 7.5 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.5 8.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.5 32.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.5 3.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centriole replication(GO:0046600) negative regulation of centrosome cycle(GO:0046606)
0.5 1.6 GO:0050748 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.5 11.1 GO:0035082 axoneme assembly(GO:0035082)
0.5 19.7 GO:0046328 regulation of JNK cascade(GO:0046328)
0.5 2.1 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.5 21.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.5 5.6 GO:0046847 filopodium assembly(GO:0046847)
0.5 13.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.5 17.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.5 3.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.5 3.8 GO:0044211 CTP salvage(GO:0044211)
0.5 10.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.5 26.8 GO:0003341 cilium movement(GO:0003341)
0.5 0.9 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.5 5.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 6.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.5 1.4 GO:0070417 cellular response to cold(GO:0070417)
0.5 2.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.5 2.7 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5 6.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.4 1.8 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.4 1.3 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.4 30.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.4 1.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.4 4.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.4 2.9 GO:0016266 O-glycan processing(GO:0016266)
0.4 3.4 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.4 1.7 GO:0070555 response to interleukin-1(GO:0070555) cellular response to interleukin-1(GO:0071347)
0.4 18.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.4 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.4 2.8 GO:0045444 fat cell differentiation(GO:0045444)
0.4 9.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.4 5.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.4 1.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.4 3.0 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.4 32.2 GO:0006475 internal protein amino acid acetylation(GO:0006475) internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394)
0.4 4.0 GO:0006382 adenosine to inosine editing(GO:0006382)
0.4 6.8 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.4 2.8 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.3 29.6 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.3 6.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 4.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.3 17.9 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.3 43.2 GO:0007018 microtubule-based movement(GO:0007018)
0.3 3.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3 19.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.3 5.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 11.5 GO:0031647 regulation of protein stability(GO:0031647)
0.3 4.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 4.6 GO:0006265 DNA topological change(GO:0006265)
0.3 17.4 GO:0006476 protein deacetylation(GO:0006476)
0.3 8.2 GO:0060968 regulation of gene silencing(GO:0060968)
0.3 2.1 GO:2000404 regulation of T cell migration(GO:2000404)
0.3 2.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 12.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 2.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 1.7 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.3 1.7 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 27.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.3 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 9.4 GO:0016126 sterol biosynthetic process(GO:0016126)
0.3 5.9 GO:0003094 glomerular filtration(GO:0003094)
0.3 10.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.3 9.0 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.3 50.0 GO:0006470 protein dephosphorylation(GO:0006470)
0.3 2.8 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2 1.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2 11.3 GO:0007338 single fertilization(GO:0007338)
0.2 12.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 5.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 1.7 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.2 1.6 GO:0031179 peptide modification(GO:0031179)
0.2 0.6 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 3.1 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.2 5.3 GO:0007062 sister chromatid cohesion(GO:0007062)
0.2 2.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 5.0 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.2 6.5 GO:0034111 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.2 3.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 1.6 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 1.0 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.2 5.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.2 2.0 GO:0018345 protein palmitoylation(GO:0018345)
0.2 4.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 7.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.2 1.9 GO:0006513 protein monoubiquitination(GO:0006513)
0.2 3.3 GO:0035195 gene silencing by miRNA(GO:0035195)
0.2 6.2 GO:0043087 regulation of GTPase activity(GO:0043087)
0.2 1.8 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.1 2.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.3 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.1 1.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.6 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 1.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 3.4 GO:0016574 histone ubiquitination(GO:0016574)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 8.8 GO:0016579 protein deubiquitination(GO:0016579)
0.1 1.0 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.4 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.1 1.4 GO:0032438 melanosome organization(GO:0032438)
0.1 0.7 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.7 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 0.4 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.4 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.1 1.4 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.9 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 1.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 4.8 GO:0010506 regulation of autophagy(GO:0010506)
0.1 2.4 GO:0030488 tRNA methylation(GO:0030488)
0.1 13.5 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1 20.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.7 GO:0006672 ceramide metabolic process(GO:0006672)
0.1 1.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.2 GO:0042148 strand invasion(GO:0042148)
0.1 4.0 GO:0007034 vacuolar transport(GO:0007034)
0.1 0.9 GO:0031503 protein complex localization(GO:0031503)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.5 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.2 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.3 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
27.3 109.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
17.4 104.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
14.4 143.7 GO:0098982 GABA-ergic synapse(GO:0098982)
11.0 66.2 GO:0005955 calcineurin complex(GO:0005955)
9.6 57.3 GO:0043083 synaptic cleft(GO:0043083)
9.5 28.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
8.8 35.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
7.5 22.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
7.4 14.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
7.3 7.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
7.1 21.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
6.9 234.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
6.3 278.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
5.8 17.5 GO:0032839 dendrite cytoplasm(GO:0032839)
5.6 55.7 GO:0042583 chromaffin granule(GO:0042583)
5.5 5.5 GO:0042575 DNA polymerase complex(GO:0042575)
4.9 59.1 GO:0044295 axonal growth cone(GO:0044295)
4.7 198.5 GO:0030426 growth cone(GO:0030426)
4.6 346.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
4.6 142.8 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
4.4 88.6 GO:0031594 neuromuscular junction(GO:0031594)
4.3 13.0 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
4.2 62.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
4.0 31.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
3.8 50.0 GO:1990246 uniplex complex(GO:1990246)
3.8 91.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
3.3 13.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
3.3 23.2 GO:0043194 axon initial segment(GO:0043194)
3.1 21.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
3.1 49.0 GO:0031209 SCAR complex(GO:0031209)
3.0 35.6 GO:0030893 meiotic cohesin complex(GO:0030893)
2.9 23.5 GO:0044232 organelle membrane contact site(GO:0044232)
2.9 20.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.9 23.0 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
2.8 50.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
2.7 2.7 GO:0071564 npBAF complex(GO:0071564)
2.6 21.2 GO:0016586 RSC complex(GO:0016586)
2.6 23.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
2.6 18.2 GO:0033270 paranode region of axon(GO:0033270)
2.6 7.8 GO:0042382 paraspeckles(GO:0042382)
2.6 10.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
2.6 23.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
2.5 19.8 GO:0034464 BBSome(GO:0034464)
2.5 7.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
2.4 16.8 GO:0033010 paranodal junction(GO:0033010)
2.4 165.1 GO:0031201 SNARE complex(GO:0031201)
2.3 217.8 GO:0008021 synaptic vesicle(GO:0008021)
2.3 22.6 GO:0036449 microtubule minus-end(GO:0036449)
2.2 36.8 GO:0043209 myelin sheath(GO:0043209)
2.2 8.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
2.2 154.9 GO:0043025 neuronal cell body(GO:0043025)
2.1 27.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
2.1 6.4 GO:0032591 dendritic spine membrane(GO:0032591)
2.1 40.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
2.1 12.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
2.1 128.5 GO:0034704 calcium channel complex(GO:0034704)
2.1 6.3 GO:0005828 kinetochore microtubule(GO:0005828)
2.1 34.9 GO:0030008 TRAPP complex(GO:0030008)
2.0 50.8 GO:0005921 gap junction(GO:0005921)
2.0 41.9 GO:0002116 semaphorin receptor complex(GO:0002116)
2.0 7.9 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
2.0 15.8 GO:0005614 interstitial matrix(GO:0005614)
1.9 44.5 GO:0048786 presynaptic active zone(GO:0048786)
1.9 20.4 GO:0061617 MICOS complex(GO:0061617)
1.8 9.0 GO:0008091 spectrin(GO:0008091)
1.8 113.5 GO:0031225 anchored component of membrane(GO:0031225)
1.8 25.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
1.8 17.9 GO:0045171 intercellular bridge(GO:0045171)
1.8 214.4 GO:0045211 postsynaptic membrane(GO:0045211)
1.8 31.6 GO:0005640 nuclear outer membrane(GO:0005640)
1.7 98.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
1.6 185.1 GO:0014069 postsynaptic density(GO:0014069)
1.6 31.0 GO:0044666 MLL3/4 complex(GO:0044666)
1.6 45.6 GO:0098978 glutamatergic synapse(GO:0098978)
1.6 48.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
1.6 109.0 GO:0030141 secretory granule(GO:0030141)
1.6 4.9 GO:0072380 TRC complex(GO:0072380)
1.6 35.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
1.5 26.3 GO:0060170 ciliary membrane(GO:0060170)
1.5 40.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
1.5 29.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.5 7.4 GO:0070724 BMP receptor complex(GO:0070724)
1.5 33.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
1.4 17.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.4 10.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
1.4 5.5 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
1.4 112.9 GO:0005871 kinesin complex(GO:0005871)
1.3 13.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.3 3.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
1.3 10.4 GO:0032783 ELL-EAF complex(GO:0032783)
1.3 551.7 GO:0043005 neuron projection(GO:0043005)
1.3 6.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.3 8.9 GO:0001650 fibrillar center(GO:0001650)
1.2 15.0 GO:0030126 COPI vesicle coat(GO:0030126)
1.2 27.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
1.2 26.9 GO:0030125 clathrin vesicle coat(GO:0030125)
1.2 8.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.2 21.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
1.2 4.8 GO:0097268 cytoophidium(GO:0097268)
1.2 9.5 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
1.2 13.0 GO:0000124 SAGA complex(GO:0000124)
1.2 5.8 GO:0071203 WASH complex(GO:0071203)
1.1 9.1 GO:0071914 prominosome(GO:0071914)
1.1 5.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.1 6.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
1.1 10.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.1 2.1 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
1.1 15.8 GO:0098802 plasma membrane receptor complex(GO:0098802)
1.0 10.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
1.0 12.4 GO:0036038 MKS complex(GO:0036038)
1.0 4.1 GO:0005880 nuclear microtubule(GO:0005880)
1.0 3.1 GO:0031417 NatC complex(GO:0031417)
1.0 20.0 GO:0034399 nuclear periphery(GO:0034399)
1.0 8.0 GO:0097225 sperm midpiece(GO:0097225)
1.0 119.1 GO:0045202 synapse(GO:0045202)
1.0 31.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.0 6.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.0 23.4 GO:0005844 polysome(GO:0005844)
0.9 2.7 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.9 2.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.8 3.4 GO:0016589 NURF complex(GO:0016589)
0.8 79.9 GO:0005802 trans-Golgi network(GO:0005802)
0.8 3.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.8 18.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.8 3.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.8 3.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.8 7.0 GO:0071797 LUBAC complex(GO:0071797)
0.8 10.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.7 19.2 GO:0000145 exocyst(GO:0000145)
0.7 3.5 GO:0033503 HULC complex(GO:0033503)
0.7 4.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.7 12.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.6 5.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.6 1.9 GO:1990879 CST complex(GO:1990879)
0.6 2.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.6 3.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.6 4.3 GO:0070847 core mediator complex(GO:0070847)
0.6 9.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.6 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.6 7.0 GO:0000815 ESCRT III complex(GO:0000815)
0.6 7.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.6 4.6 GO:0030670 endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.6 12.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.5 7.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.5 16.2 GO:0030286 dynein complex(GO:0030286)
0.5 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 10.8 GO:0070822 Sin3-type complex(GO:0070822)
0.5 14.5 GO:0000922 spindle pole(GO:0000922)
0.5 2.9 GO:0071986 Ragulator complex(GO:0071986)
0.5 2.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 6.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.4 24.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.4 5.3 GO:0008278 cohesin complex(GO:0008278)
0.4 4.8 GO:0005675 holo TFIIH complex(GO:0005675)
0.4 1.7 GO:0097519 DNA recombinase complex(GO:0097519)
0.4 40.7 GO:0005770 late endosome(GO:0005770)
0.4 12.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.4 33.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 25.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.4 51.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.4 2.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.4 5.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.4 9.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 7.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.4 13.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.4 8.9 GO:0000421 autophagosome membrane(GO:0000421)
0.3 2.4 GO:0035517 PR-DUB complex(GO:0035517)
0.3 4.6 GO:0030056 hemidesmosome(GO:0030056)
0.3 2.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 13.7 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.3 2.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.3 11.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 4.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 14.1 GO:0031514 motile cilium(GO:0031514)
0.3 64.8 GO:0005768 endosome(GO:0005768)
0.3 319.7 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.3 13.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 6.6 GO:0071565 nBAF complex(GO:0071565)
0.3 3.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.3 74.4 GO:0000139 Golgi membrane(GO:0000139)
0.3 1.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 22.6 GO:0005874 microtubule(GO:0005874)
0.2 2.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 89.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.2 2.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 1.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 11.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 4.5 GO:0035861 site of double-strand break(GO:0035861)
0.2 2.4 GO:0032993 protein-DNA complex(GO:0032993)
0.2 12.6 GO:0005925 focal adhesion(GO:0005925)
0.1 3.0 GO:0030175 filopodium(GO:0030175)
0.1 1.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.7 GO:0055087 Ski complex(GO:0055087)
0.1 1.6 GO:0030427 site of polarized growth(GO:0030427)
0.1 658.6 GO:0005634 nucleus(GO:0005634)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.6 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
33.3 99.8 GO:1903136 cuprous ion binding(GO:1903136)
29.3 88.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
27.3 109.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
18.2 273.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
16.3 97.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
15.8 63.4 GO:0044548 S100 protein binding(GO:0044548)
14.4 201.1 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
11.4 45.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
11.0 66.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
9.7 29.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
9.7 174.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
9.6 385.5 GO:0017075 syntaxin-1 binding(GO:0017075)
9.6 28.7 GO:0038046 enkephalin receptor activity(GO:0038046)
8.9 35.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
7.5 89.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
7.1 42.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
6.7 26.9 GO:0070324 thyroid hormone binding(GO:0070324)
5.8 23.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
5.7 23.0 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
4.9 14.7 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
4.8 24.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
4.8 14.4 GO:0031716 calcitonin receptor binding(GO:0031716)
4.6 23.1 GO:0008046 axon guidance receptor activity(GO:0008046)
4.6 41.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
4.5 58.5 GO:0031628 opioid receptor binding(GO:0031628)
4.5 13.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
4.4 17.8 GO:0002151 G-quadruplex RNA binding(GO:0002151)
4.4 21.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
4.3 103.6 GO:0001540 beta-amyloid binding(GO:0001540)
4.3 72.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
4.1 74.5 GO:0004383 guanylate cyclase activity(GO:0004383)
4.1 53.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
4.1 12.3 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
4.1 8.1 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
4.0 28.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
4.0 31.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
4.0 43.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
3.9 35.5 GO:0004359 glutaminase activity(GO:0004359)
3.9 189.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
3.9 15.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
3.9 27.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
3.8 23.0 GO:0030331 estrogen receptor binding(GO:0030331)
3.8 49.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
3.8 64.1 GO:0045159 myosin II binding(GO:0045159)
3.7 51.9 GO:0008327 methyl-CpG binding(GO:0008327)
3.7 77.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
3.6 28.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.5 14.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
3.5 31.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
3.4 91.9 GO:0017080 sodium channel regulator activity(GO:0017080)
3.4 16.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
3.3 9.9 GO:1990226 histone methyltransferase binding(GO:1990226)
3.3 16.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
3.3 42.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
3.1 62.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
3.1 15.7 GO:0070300 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611)
3.1 12.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
3.1 9.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
3.0 36.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
3.0 9.0 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
3.0 12.0 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
2.9 26.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
2.9 8.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.9 86.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
2.9 23.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
2.9 11.5 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
2.9 17.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.8 54.0 GO:0008301 DNA binding, bending(GO:0008301)
2.8 14.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
2.8 45.3 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
2.8 8.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
2.7 39.9 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
2.6 23.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
2.6 44.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
2.5 53.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.5 42.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
2.5 15.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
2.5 12.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
2.5 22.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.5 36.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.4 7.3 GO:0052834 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
2.4 24.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
2.4 7.2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
2.4 9.6 GO:0001607 neuromedin U receptor activity(GO:0001607)
2.4 9.6 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
2.4 7.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
2.4 12.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.4 19.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
2.4 14.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
2.4 30.6 GO:0016413 O-acetyltransferase activity(GO:0016413)
2.2 4.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
2.2 19.8 GO:0048039 ubiquinone binding(GO:0048039)
2.2 83.0 GO:0030145 manganese ion binding(GO:0030145)
2.2 15.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.1 6.3 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
2.1 56.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
2.1 31.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
2.1 26.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
2.0 12.3 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
2.0 6.1 GO:0001729 ceramide kinase activity(GO:0001729)
2.0 57.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
2.0 10.2 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
2.0 10.2 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
2.0 97.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
2.0 6.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
2.0 8.1 GO:0033149 FFAT motif binding(GO:0033149)
2.0 28.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
2.0 28.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
2.0 26.0 GO:0030507 spectrin binding(GO:0030507)
2.0 7.9 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
2.0 27.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
1.9 60.1 GO:0017154 semaphorin receptor activity(GO:0017154)
1.9 32.4 GO:0008417 fucosyltransferase activity(GO:0008417)
1.9 1.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.9 5.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.8 11.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
1.8 11.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
1.8 19.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
1.8 10.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.8 21.3 GO:0051011 microtubule minus-end binding(GO:0051011)
1.8 42.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.8 14.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.8 10.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.7 34.6 GO:0022829 wide pore channel activity(GO:0022829)
1.7 8.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.7 6.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.7 33.4 GO:0016917 GABA receptor activity(GO:0016917)
1.7 57.9 GO:0051010 microtubule plus-end binding(GO:0051010)
1.6 26.3 GO:0017136 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
1.6 25.9 GO:0042910 xenobiotic transporter activity(GO:0042910)
1.6 19.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.6 4.7 GO:0004061 arylformamidase activity(GO:0004061)
1.6 14.0 GO:0030547 receptor inhibitor activity(GO:0030547)
1.5 6.2 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
1.5 23.1 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
1.5 50.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.5 33.1 GO:0050321 tau-protein kinase activity(GO:0050321)
1.5 13.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.5 47.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.5 13.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.5 13.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.5 24.7 GO:0005272 sodium channel activity(GO:0005272)
1.5 7.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.4 5.8 GO:0033745 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
1.4 32.7 GO:0016854 racemase and epimerase activity(GO:0016854)
1.4 18.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
1.4 19.7 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.4 21.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.4 48.6 GO:0019003 GDP binding(GO:0019003)
1.3 144.1 GO:0005516 calmodulin binding(GO:0005516)
1.3 8.0 GO:0008158 hedgehog receptor activity(GO:0008158)
1.3 10.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.3 25.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
1.3 3.9 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
1.3 6.5 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
1.3 3.9 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.3 5.1 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
1.3 7.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.2 1.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.2 27.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.2 4.8 GO:0003883 CTP synthase activity(GO:0003883)
1.2 3.5 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
1.2 60.0 GO:0019905 syntaxin binding(GO:0019905)
1.2 41.9 GO:0004707 MAP kinase activity(GO:0004707)
1.1 4.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.1 11.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.1 13.7 GO:0043014 alpha-tubulin binding(GO:0043014)
1.1 8.0 GO:0004995 tachykinin receptor activity(GO:0004995)
1.1 8.0 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
1.1 3.4 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
1.1 7.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.1 26.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
1.1 5.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.1 7.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.1 7.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 7.5 GO:0016918 retinal binding(GO:0016918)
1.1 35.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
1.1 14.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.0 99.7 GO:0045296 cadherin binding(GO:0045296)
1.0 23.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
1.0 12.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
1.0 23.9 GO:0008378 galactosyltransferase activity(GO:0008378)
1.0 7.8 GO:0015232 heme transporter activity(GO:0015232)
1.0 7.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.9 25.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.9 29.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.9 6.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.9 4.6 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.9 19.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.9 20.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.9 281.0 GO:0015631 tubulin binding(GO:0015631)
0.9 11.3 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.9 3.5 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.9 1.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.9 26.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.8 5.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.8 6.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.8 2.5 GO:0071568 UFM1 transferase activity(GO:0071568)
0.8 8.2 GO:0005042 netrin receptor activity(GO:0005042)
0.8 5.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.8 4.9 GO:0019107 myristoyltransferase activity(GO:0019107)
0.8 9.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.8 8.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.8 7.2 GO:0005113 patched binding(GO:0005113)
0.8 4.0 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.8 31.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.8 65.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.8 46.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.8 17.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 6.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.8 3.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.8 2.3 GO:0047690 aspartyltransferase activity(GO:0047690)
0.8 2.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.8 3.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.8 6.8 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 1.5 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.8 5.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.8 33.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.7 3.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.7 14.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.7 8.8 GO:0048495 Roundabout binding(GO:0048495)
0.7 18.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.7 5.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.7 17.5 GO:0031267 small GTPase binding(GO:0031267)
0.7 7.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.7 10.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.7 3.6 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.7 4.3 GO:0043531 ADP binding(GO:0043531)
0.7 8.5 GO:0005158 insulin receptor binding(GO:0005158)
0.7 11.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.7 283.0 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.7 64.0 GO:0022832 voltage-gated channel activity(GO:0022832)
0.7 4.6 GO:0030371 translation repressor activity(GO:0030371)
0.7 235.5 GO:0005096 GTPase activator activity(GO:0005096)
0.7 2.0 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.6 3.9 GO:0004985 opioid receptor activity(GO:0004985)
0.6 9.7 GO:0035064 methylated histone binding(GO:0035064)
0.6 200.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.6 8.9 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.6 7.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.6 13.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.6 7.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.6 11.1 GO:0033691 sialic acid binding(GO:0033691)
0.6 24.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.6 2.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6 3.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.6 24.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6 2.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.6 2.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.6 5.4 GO:0008013 beta-catenin binding(GO:0008013)
0.6 2.9 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.6 18.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.6 194.0 GO:0003924 GTPase activity(GO:0003924)
0.5 11.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.5 38.8 GO:0042802 identical protein binding(GO:0042802)
0.5 7.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.5 6.4 GO:0005231 extracellular ATP-gated cation channel activity(GO:0004931) excitatory extracellular ligand-gated ion channel activity(GO:0005231) ATP-gated ion channel activity(GO:0035381)
0.5 0.5 GO:0003994 aconitate hydratase activity(GO:0003994)
0.5 1.6 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.5 15.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.5 8.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.5 8.6 GO:0002039 p53 binding(GO:0002039)
0.5 5.3 GO:0015278 calcium-release channel activity(GO:0015278)
0.5 14.1 GO:0005254 chloride channel activity(GO:0005254)
0.5 2.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5 4.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.5 11.0 GO:0035591 signaling adaptor activity(GO:0035591)
0.5 4.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.5 3.8 GO:0004849 uridine kinase activity(GO:0004849)
0.5 0.9 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.5 17.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.5 3.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5 3.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.5 9.3 GO:0097602 cullin family protein binding(GO:0097602)
0.5 12.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 405.2 GO:0005509 calcium ion binding(GO:0005509)
0.4 5.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 13.2 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.4 13.0 GO:0044325 ion channel binding(GO:0044325)
0.4 18.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.4 1.7 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.4 2.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.4 4.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.4 1.6 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.4 5.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 2.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 4.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.4 2.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.4 1.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 2.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.4 2.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 5.8 GO:0015026 coreceptor activity(GO:0015026)
0.3 36.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 2.0 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.3 9.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 16.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.3 34.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 3.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3 4.8 GO:0016018 drug binding(GO:0008144) cyclosporin A binding(GO:0016018)
0.3 0.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 1.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 3.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 6.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.5 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.3 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 2.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.3 3.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 11.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.3 5.8 GO:0051018 protein kinase A binding(GO:0051018)
0.3 4.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.3 1.9 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3 3.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 7.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.2 1.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 59.0 GO:0003682 chromatin binding(GO:0003682)
0.2 108.3 GO:0046983 protein dimerization activity(GO:0046983)
0.2 2.6 GO:0043495 protein anchor(GO:0043495)
0.2 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 2.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 3.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 1.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 1.0 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 11.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 3.3 GO:0035497 cAMP response element binding(GO:0035497)
0.2 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.2 1.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2 2.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 396.6 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.2 8.4 GO:0000146 microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.2 3.0 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.2 9.0 GO:0008170 N-methyltransferase activity(GO:0008170)
0.2 8.0 GO:0071949 FAD binding(GO:0071949)
0.2 3.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 2.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 2.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 4.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 3.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 13.0 GO:0003690 double-stranded DNA binding(GO:0003690)
0.1 66.0 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.1 0.2 GO:0005521 lamin binding(GO:0005521)
0.1 31.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 2.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.5 GO:0019213 deacetylase activity(GO:0019213)
0.1 11.1 GO:0005179 hormone activity(GO:0005179)
0.1 0.4 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 12.0 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.7 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 2.9 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 2.0 GO:0019239 deaminase activity(GO:0019239)
0.1 0.9 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.2 GO:0030276 clathrin binding(GO:0030276)
0.1 12.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 1.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0016836 hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 84.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
3.4 26.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
3.1 36.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
2.2 65.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
2.0 42.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
2.0 44.1 PID NETRIN PATHWAY Netrin-mediated signaling events
2.0 39.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
1.9 27.2 PID LPA4 PATHWAY LPA4-mediated signaling events
1.7 74.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
1.7 48.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.7 35.0 PID EPHA FWDPATHWAY EPHA forward signaling
1.6 12.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.5 42.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
1.4 13.9 PID S1P S1P1 PATHWAY S1P1 pathway
1.4 28.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
1.3 10.6 PID REELIN PATHWAY Reelin signaling pathway
1.3 44.9 ST G ALPHA I PATHWAY G alpha i Pathway
1.3 17.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
1.2 54.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
1.1 37.2 PID ATM PATHWAY ATM pathway
1.1 22.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
1.0 7.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
1.0 24.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
1.0 3.9 ST ADRENERGIC Adrenergic Pathway
1.0 15.6 PID RHOA PATHWAY RhoA signaling pathway
0.9 20.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.9 8.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.8 18.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.8 13.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.8 10.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.8 12.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.8 45.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.7 6.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 2.9 PID IGF1 PATHWAY IGF1 pathway
0.7 2.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.7 8.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.7 21.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.6 26.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.6 4.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.6 6.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.6 21.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.6 7.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.6 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 13.5 PID AP1 PATHWAY AP-1 transcription factor network
0.4 6.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.4 6.8 PID ARF 3PATHWAY Arf1 pathway
0.3 6.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 1.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.3 10.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 2.8 PID FOXO PATHWAY FoxO family signaling
0.2 3.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.8 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
16.0 79.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
13.5 202.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
9.9 29.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
7.7 53.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
5.7 51.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
5.7 79.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
5.4 65.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
5.0 5.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
4.4 26.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
3.6 29.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
3.5 38.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
3.4 41.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
3.2 45.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
3.2 19.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
3.0 27.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
2.6 15.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
2.5 27.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
2.4 24.0 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
2.3 20.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
2.2 21.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
2.1 8.5 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
2.1 33.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.0 37.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
1.9 7.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
1.9 21.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
1.9 17.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
1.9 19.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
1.8 37.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
1.6 42.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
1.6 11.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.5 14.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
1.5 35.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
1.3 44.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
1.2 15.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.1 59.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
1.1 7.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.1 35.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
1.1 12.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
1.0 5.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.9 2.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.9 1.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.9 28.3 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.8 5.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.8 57.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.8 8.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.8 43.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.8 12.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 12.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.7 3.6 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.7 12.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 9.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6 2.5 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.6 3.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 26.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.6 3.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.6 20.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.5 5.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.5 6.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 7.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.5 18.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.5 6.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 7.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5 5.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.4 12.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 12.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.4 15.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.4 4.7 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.4 32.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.4 4.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 40.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 9.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 4.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.4 4.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.3 9.1 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.3 21.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.3 13.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 6.6 REACTOME KINESINS Genes involved in Kinesins
0.3 3.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 5.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 4.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 3.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 12.7 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.2 1.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.2 4.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.2 2.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.2 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 4.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 11.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 5.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 1.9 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 2.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 6.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 4.3 REACTOME MEIOSIS Genes involved in Meiosis
0.1 1.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 6.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 1.0 REACTOME PROTEIN FOLDING Genes involved in Protein folding