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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxb9a

Z-value: 0.52

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Transcription factors associated with hoxb9a

Gene Symbol Gene ID Gene Info
ENSDARG00000056023 homeobox B9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb9adr11_v1_chr3_+_23677351_23677351-0.141.9e-01Click!

Activity profile of hoxb9a motif

Sorted Z-values of hoxb9a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_7379728 9.40 ENSDART00000012194
GATA binding protein 5
chr12_-_20373058 7.00 ENSDART00000066382
aquaporin 8a, tandem duplicate 1
chr4_+_7391110 4.28 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr11_-_18253111 4.07 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr2_+_52847049 3.89 ENSDART00000121980
cAMP responsive element binding protein 3-like 3b
chr15_+_20403903 3.86 ENSDART00000134182
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr1_+_17900306 3.56 ENSDART00000089480
cytochrome P450, family 4, subfamily V, polypeptide 8
chr9_-_9980704 3.34 ENSDART00000130243
ENSDART00000193475
UDP glucuronosyltransferase 1 family a, b
chr23_+_10352921 3.10 ENSDART00000081193
si:ch211-133j6.3
chr11_+_24314148 3.09 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr23_+_18722915 3.06 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr23_+_18722715 3.05 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr24_+_39105051 2.94 ENSDART00000115297
MSS51 mitochondrial translational activator
chr23_+_39606108 2.80 ENSDART00000109464
G0/G1 switch 2
chr1_-_9249943 2.73 ENSDART00000055011
zgc:136472
chr21_+_11969603 2.57 ENSDART00000142247
ENSDART00000140652
motilin-like
chr21_-_19918286 2.29 ENSDART00000180816
protein phosphatase 1, regulatory subunit 3B
chr15_+_45586471 2.26 ENSDART00000165699
claudin 15-like b
chr20_+_52546186 1.80 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr11_+_44503774 1.76 ENSDART00000169295
endoplasmic reticulum oxidoreductase beta
chr21_-_2415808 1.72 ENSDART00000171179
si:ch211-241b2.5
chr18_-_48296793 1.69 ENSDART00000032184
ENSDART00000193076

chr12_-_33817114 1.62 ENSDART00000161265
twinkle mtDNA helicase
chr25_+_32755485 1.60 ENSDART00000162188
electron-transfer-flavoprotein, alpha polypeptide
chr25_+_29161609 1.53 ENSDART00000180752
pyruvate kinase M1/2b
chr10_-_7785930 1.53 ENSDART00000043961
ENSDART00000111058
myeloid-specific peroxidase
chr24_-_32025637 1.53 ENSDART00000180448
ENSDART00000159034
Ras suppressor protein 1
chr14_+_15495088 1.52 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
chr7_+_27317174 1.49 ENSDART00000193058
SRY (sex determining region Y)-box 6
chr11_-_25538341 1.46 ENSDART00000171560
si:dkey-245f22.3
chr24_+_1042594 1.42 ENSDART00000109117
si:dkey-192l18.9
chr8_-_38159805 1.31 ENSDART00000112331
ENSDART00000180006
adhesion G protein-coupled receptor A2
chr15_+_32405959 1.31 ENSDART00000177269
si:ch211-162k9.6
chr10_+_44700103 1.29 ENSDART00000165999
scavenger receptor class B, member 1
chr17_+_33375469 1.27 ENSDART00000032827
zgc:162964
chr17_+_15788100 1.26 ENSDART00000027667
ras-related GTP binding D
chr10_+_40321067 1.22 ENSDART00000109816
glycolipid transfer protein b
chr3_+_36646054 1.15 ENSDART00000170013
ENSDART00000159948
G1 to S phase transition 1, like
chr5_-_32336613 1.14 ENSDART00000139732
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr20_-_2641233 1.14 ENSDART00000145335
ENSDART00000133121
BUB1 mitotic checkpoint serine/threonine kinase
chr9_-_22355391 1.11 ENSDART00000009115
crystallin, gamma M3
chr7_+_24522308 1.11 ENSDART00000173542
bloodthirsty-related gene family, member 9
chr24_-_9997948 1.11 ENSDART00000136274
si:ch211-146l10.7
chr15_-_21014015 1.10 ENSDART00000144991
si:ch211-212c13.10
chr10_+_15107886 1.09 ENSDART00000188047
ENSDART00000164095
secretory calcium-binding phosphoprotein 8
chr7_+_33152723 1.08 ENSDART00000132658
si:ch211-194p6.10
chr11_-_15090118 1.08 ENSDART00000171118
solute carrier family 1 (glutamate transporter), member 8a
chr24_-_14712427 1.07 ENSDART00000176316
junctophilin 1a
chr1_+_44439661 1.07 ENSDART00000100309
crystallin, beta B1, like 2
chr5_+_72194444 1.02 ENSDART00000165436
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr3_-_49554912 0.99 ENSDART00000159392

chr15_+_29727799 0.99 ENSDART00000182006
zgc:153372
chr2_+_15586632 0.98 ENSDART00000164903

chr16_-_27566552 0.97 ENSDART00000142102
zgc:153215
chr13_-_33362191 0.97 ENSDART00000100514
zgc:172120
chr13_-_11578304 0.96 ENSDART00000171145
si:ch211-132e22.4
chr8_+_45004997 0.96 ENSDART00000159779
si:ch211-163b2.4
chr8_+_45004666 0.93 ENSDART00000145348
si:ch211-163b2.4
chr7_-_7692723 0.92 ENSDART00000183352
aminoadipate aminotransferase
chr10_+_40660772 0.92 ENSDART00000148007
trace amine associated receptor 19l
chr10_+_26612321 0.92 ENSDART00000134322
four and a half LIM domains 1b
chr3_-_34089310 0.91 ENSDART00000151774
immunoglobulin heavy variable 5-5
chr17_-_43666166 0.91 ENSDART00000077990
early growth response 2a
chr3_-_34624745 0.91 ENSDART00000151091
tachykinin 4 (hemokinin)
chr21_-_39931285 0.90 ENSDART00000180010
ENSDART00000024407
transmembrane and immunoglobulin domain containing 1
chr7_-_18508815 0.90 ENSDART00000173539
regulator of G protein signaling 12a
chr23_-_21215311 0.87 ENSDART00000112424
multiple EGF-like-domains 6a
chr5_-_57723929 0.87 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr7_-_7692992 0.86 ENSDART00000192619
aminoadipate aminotransferase
chr16_-_16225260 0.86 ENSDART00000165790
granulito
chr21_-_39024754 0.86 ENSDART00000056878
tnf receptor-associated factor 4b
chr5_-_9625459 0.85 ENSDART00000143347
SH2B adaptor protein 3
chr2_-_40196547 0.85 ENSDART00000168098
chemokine (C-C motif) ligand 34a, duplicate 3
chr12_+_27704015 0.84 ENSDART00000153256
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr6_+_13083146 0.84 ENSDART00000172158
trans-L-3-hydroxyproline dehydratase
chr10_+_506538 0.83 ENSDART00000141713
si:ch211-242f23.3
chr21_-_11970199 0.82 ENSDART00000114524
NOP56 ribonucleoprotein homolog
chr15_-_2841677 0.82 ENSDART00000026145
ENSDART00000180290
angiomotin like 1
chr3_+_58119571 0.81 ENSDART00000108979
si:ch211-256e16.4
chr22_-_4644484 0.80 ENSDART00000167748
fibrillin 2b
chr4_-_77300601 0.79 ENSDART00000163015
ENSDART00000174015
solute carrier organic anion transporter family, member 1F2
chr2_-_3158919 0.78 ENSDART00000098394
wingless-type MMTV integration site family, member 3A
chr11_-_15090564 0.75 ENSDART00000162079
solute carrier family 1 (glutamate transporter), member 8a
chr24_-_31452875 0.75 ENSDART00000187381
ENSDART00000185128
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr10_-_40484531 0.74 ENSDART00000142464
ENSDART00000180318
trace amine associated receptor 20z
chr19_+_19747430 0.71 ENSDART00000166129
homeobox A9a
chr17_-_30652738 0.71 ENSDART00000154960
SH3 and SYLF domain containing 1
chr11_-_38533505 0.71 ENSDART00000113894
solute carrier family 45, member 3
chr23_+_3625083 0.71 ENSDART00000184958
si:dkey-9l20.3
chr10_+_40768203 0.70 ENSDART00000171994
ENSDART00000140343
trace amine associated receptor 19d
chr25_-_19219807 0.70 ENSDART00000183577
aggrecan b
chr5_+_24087035 0.69 ENSDART00000183644
tumor protein p53
chr15_+_31515976 0.68 ENSDART00000156471
testis expressed 26
chr13_+_1182257 0.68 ENSDART00000033528
ENSDART00000183702
ENSDART00000147959
tumor necrosis factor, alpha-induced protein 3
chr20_+_46202188 0.67 ENSDART00000100523
trace amine associated receptor 13c
chr2_+_19578079 0.67 ENSDART00000144413
Pim proto-oncogene, serine/threonine kinase, related 50
chr1_+_56463494 0.66 ENSDART00000097964
zgc:171452
chr23_+_36122058 0.66 ENSDART00000184448
homeobox C3a
chr17_-_36841981 0.66 ENSDART00000131566
myosin VIb
chr24_-_3426620 0.65 ENSDART00000184346
NCK adaptor protein 1b
chr20_-_2713120 0.65 ENSDART00000138753
ENSDART00000104606
arginyl-tRNA synthetase 2, mitochondrial (putative)
chr25_-_31898552 0.65 ENSDART00000156128
si:ch73-330k17.3
chr24_+_30392834 0.64 ENSDART00000162555
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr4_-_11122638 0.64 ENSDART00000150600
si:dkey-21h14.10
chr7_+_29512673 0.63 ENSDART00000173895
si:dkey-182o15.5
chr2_-_32637592 0.62 ENSDART00000136353
si:dkeyp-73d8.8
chr10_-_3332362 0.62 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr11_+_12175162 0.60 ENSDART00000125446
si:ch211-156l18.7
chr11_+_42585138 0.58 ENSDART00000019008
ankyrin repeat and SOCS box containing 14a
chr14_+_22447662 0.58 ENSDART00000161776
sosondowah ankyrin repeat domain family member Ab
chr11_+_45323455 0.57 ENSDART00000189249
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr8_-_6897619 0.57 ENSDART00000133606
si:ch211-255g12.8
chr20_-_31496679 0.56 ENSDART00000153437
ENSDART00000153193
SAM and SH3 domain containing 1a
chr4_+_59711338 0.53 ENSDART00000150849
si:dkey-149m13.4
chr6_-_54107269 0.52 ENSDART00000190017
hyaluronoglucosaminidase 2a
chr4_-_64142389 0.51 ENSDART00000172126

chr10_-_1625080 0.51 ENSDART00000137285
nucleoporin 155
chr4_+_45504938 0.51 ENSDART00000145958
si:dkey-256i11.2
chr20_-_47270519 0.48 ENSDART00000153329
si:dkeyp-104f11.8
chr5_-_39698224 0.48 ENSDART00000076929
protein kinase, cGMP-dependent, type II
chr17_-_50050453 0.47 ENSDART00000182057
zgc:100951
chr13_+_27329556 0.47 ENSDART00000140085
Mab-21 domain containing 1
chr11_-_38492269 0.47 ENSDART00000065613
ELK4, ETS-domain protein
chr17_-_21057617 0.46 ENSDART00000148095
ENSDART00000048853
ubiquitin-conjugating enzyme E2D 1a
chr5_-_30074332 0.44 ENSDART00000147963
beta-carotene oxygenase 2a
chr4_-_59159690 0.42 ENSDART00000164706
zinc finger protein 1149
chr24_-_21819010 0.42 ENSDART00000091096

chr22_+_8612462 0.39 ENSDART00000114586

chr17_-_23727978 0.39 ENSDART00000079600
multiple inositol-polyphosphate phosphatase 1a
chr18_+_8320165 0.39 ENSDART00000092053
choline kinase beta
chr4_+_33574463 0.38 ENSDART00000150255
si:dkey-84h14.1
chr4_-_50788075 0.38 ENSDART00000150302
zinc finger protein 1045
chr10_+_44699734 0.37 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scavenger receptor class B, member 1
chr4_-_61920018 0.36 ENSDART00000164832
zinc finger protein 1056
chr17_-_50059664 0.35 ENSDART00000193940

chr6_+_39536596 0.34 ENSDART00000185742

chr22_+_2512154 0.33 ENSDART00000097363
zgc:173726
chr22_+_6321038 0.32 ENSDART00000179961
si:rp71-1i20.1
chr25_-_12923482 0.31 ENSDART00000161754

chr10_+_40700311 0.31 ENSDART00000157650
ENSDART00000138342
trace amine associated receptor 19n
chr3_+_13482542 0.29 ENSDART00000161287

chr5_-_54424019 0.29 ENSDART00000169270
ENSDART00000164067
coenzyme Q4 homolog (S. cerevisiae)
chr3_+_6469754 0.29 ENSDART00000185809
nucleoporin 85
chr8_-_7847921 0.27 ENSDART00000188094
zgc:113363
chr22_+_21255860 0.26 ENSDART00000134893
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr24_+_29352039 0.25 ENSDART00000101641
protein arginine methyltransferase 6
chr5_-_30984271 0.24 ENSDART00000051392
spinster homolog 3 (Drosophila)
chr4_-_71108793 0.24 ENSDART00000189856
si:dkeyp-80d11.1
chr10_+_16069987 0.23 ENSDART00000043936
multiple EGF-like-domains 10
chr1_-_56556326 0.23 ENSDART00000188760

chr21_-_27251112 0.22 ENSDART00000137667
MAP/microtubule affinity-regulating kinase 2a
chr4_-_55641422 0.22 ENSDART00000165178
zinc finger protein 1074
chr25_+_28823952 0.22 ENSDART00000067072
nuclear transcription factor Y, beta b
chr4_-_46915962 0.22 ENSDART00000169555
si:ch211-134c10.1
chr6_-_6345991 0.18 ENSDART00000174445
coiled-coil domain containing 88Aa
chr6_-_3982783 0.17 ENSDART00000171944
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr25_+_7299488 0.17 ENSDART00000184836
high mobility group 20A
chr13_+_22295905 0.17 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr13_-_2283176 0.16 ENSDART00000158462
leucine rich repeat containing 1
chr25_+_32496877 0.15 ENSDART00000132698
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr25_+_22572296 0.14 ENSDART00000152096
stimulated by retinoic acid 6
chr7_+_31145386 0.14 ENSDART00000075407
ENSDART00000169462
family with sequence similarity 189, member A1
chr3_-_53091946 0.14 ENSDART00000187297
lysophosphatidic acid receptor 2a
chr6_+_19948043 0.14 ENSDART00000182636
phosphoinositide-3-kinase, regulatory subunit 5
chr8_-_3312384 0.14 ENSDART00000035965
fucosyltransferase 9b
chr4_+_42556555 0.12 ENSDART00000168536
zinc finger protein 1053
chr21_+_23108420 0.12 ENSDART00000192394
ENSDART00000088459
5-hydroxytryptamine (serotonin) receptor 3B
chr6_+_41186320 0.12 ENSDART00000025241
opsin 1 (cone pigments), medium-wave-sensitive, 2
chr18_+_35173859 0.11 ENSDART00000127379
ENSDART00000098292
cilia and flagella associated protein 45
chr4_-_73190246 0.11 ENSDART00000170842

chr2_+_2967255 0.11 ENSDART00000167649
ENSDART00000166449
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr21_-_3700334 0.11 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr20_+_33532296 0.08 ENSDART00000153153
potassium voltage-gated channel, subfamily F, member 1a
chr7_-_41693004 0.07 ENSDART00000121509
MAM and LDL receptor class A domain containing 1
chr3_-_25490970 0.05 ENSDART00000184651
growth factor receptor-bound protein 2b
chr19_-_24218942 0.05 ENSDART00000189198

chr18_+_35173683 0.04 ENSDART00000192545
cilia and flagella associated protein 45
chr10_-_10969444 0.04 ENSDART00000138041
exonuclease 3'-5' domain containing 3
chr6_+_41956355 0.03 ENSDART00000176856
oxytocin receptor
chr20_-_34670236 0.02 ENSDART00000033325
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr10_-_42923385 0.01 ENSDART00000076731
acyl-CoA thioesterase 12
chr10_-_22127942 0.01 ENSDART00000133374
plac8 onzin related protein 2
chr3_+_33745014 0.00 ENSDART00000159966
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb9a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
1.2 3.6 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.8 4.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.8 2.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 3.9 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.6 3.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6 1.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 1.3 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.3 1.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.3 1.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.3 0.8 GO:0060958 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.2 1.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 1.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 0.7 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 0.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.6 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.2 1.2 GO:0035627 ceramide transport(GO:0035627)
0.2 0.5 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.2 1.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.2 1.7 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.5 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.1 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.6 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.1 1.5 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.1 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 3.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.8 GO:0021794 thalamus development(GO:0021794)
0.1 0.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 2.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 4.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.4 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 1.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.9 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 1.8 GO:0006414 translational elongation(GO:0006414)
0.0 2.7 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.5 GO:0006096 glycolytic process(GO:0006096)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.7 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 2.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.3 1.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 1.3 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.2 GO:0018444 translation release factor complex(GO:0018444)
0.2 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 4.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.1 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 6.8 GO:0016459 myosin complex(GO:0016459)
0.1 3.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.9 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.0 GO:0015250 water channel activity(GO:0015250)
0.3 1.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.0 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.3 0.9 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.3 1.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 1.8 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2 1.2 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.2 3.9 GO:0035497 cAMP response element binding(GO:0035497)
0.2 2.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 3.9 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.5 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.6 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 3.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.9 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 0.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.7 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 3.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.4 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.6 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 6.8 GO:0003774 motor activity(GO:0003774)
0.0 5.1 GO:0020037 heme binding(GO:0020037)
0.0 0.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.6 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID EPO PATHWAY EPO signaling pathway
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 10.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)