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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxc11a

Z-value: 0.97

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Transcription factors associated with hoxc11a

Gene Symbol Gene ID Gene Info
ENSDARG00000070351 homeobox C11a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc11adr11_v1_chr23_+_36074798_360748800.349.6e-04Click!

Activity profile of hoxc11a motif

Sorted Z-values of hoxc11a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_39386982 13.01 ENSDART00000146702
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr12_-_25916530 9.73 ENSDART00000186386
synuclein, gamma b (breast cancer-specific protein 1)
chr6_-_60147517 9.23 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr25_+_29161609 8.57 ENSDART00000180752
pyruvate kinase M1/2b
chr17_-_12389259 8.10 ENSDART00000185724
synaptosomal-associated protein, 25b
chr5_-_40510397 6.89 ENSDART00000146237
ENSDART00000051065
follistatin a
chr20_-_25709247 6.73 ENSDART00000146711
si:dkeyp-117h8.2
chr21_+_5129513 6.46 ENSDART00000102572
thrombospondin 4b
chr10_+_36650222 6.44 ENSDART00000126963
uncoupling protein 3
chr15_-_33896159 6.18 ENSDART00000159791
myelin associated glycoprotein
chr8_-_34052019 5.89 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pre-B-cell leukemia homeobox 3b
chr24_-_6158933 5.81 ENSDART00000021609
glutamate decarboxylase 2
chr9_+_44431174 5.66 ENSDART00000149726
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_-_40697585 5.54 ENSDART00000113196
si:ch211-157b11.14
chr3_+_29714775 5.50 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr24_-_8732519 5.28 ENSDART00000082351
transcription factor AP-2 alpha
chr7_+_25059845 5.14 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr23_-_27571667 5.11 ENSDART00000008174
phosphofructokinase, muscle a
chr17_+_52822831 5.07 ENSDART00000193368
Meis homeobox 2a
chr17_-_26721007 5.04 ENSDART00000034580
calmodulin 1a
chr18_-_14941840 4.89 ENSDART00000091729
megalencephalic leukoencephalopathy with subcortical cysts 1
chr14_-_12837052 4.83 ENSDART00000165004
ENSDART00000043180
glutamate receptor, ionotropic, AMPA 3b
chr16_-_26074529 4.73 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr9_+_44430974 4.61 ENSDART00000056846
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_+_12853655 4.36 ENSDART00000156341
family with sequence similarity 117, member Ba
chr9_+_34425736 4.17 ENSDART00000135147
si:ch211-218d20.15
chr17_-_30975978 4.16 ENSDART00000051697
Enah/Vasp-like a
chr9_-_41784799 4.15 ENSDART00000144573
ENSDART00000112542
ENSDART00000190486
obscurin-like 1b
chr2_+_21128391 4.07 ENSDART00000136814
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr14_-_12837432 4.05 ENSDART00000178444
glutamate receptor, ionotropic, AMPA 3b
chr2_+_2223837 3.96 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr23_-_12014931 3.92 ENSDART00000134652
si:dkey-178k16.1
chr6_+_52804267 3.89 ENSDART00000065681
matrilin 4
chr11_-_18253111 3.87 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr11_-_6188413 3.79 ENSDART00000109972
chemokine (C-C motif) ligand 44
chr7_+_36041509 3.79 ENSDART00000162850
iroquois homeobox 3a
chr14_+_34966598 3.72 ENSDART00000004550
ring finger protein 145a
chr5_+_36611128 3.71 ENSDART00000097684
neuro-oncological ventral antigen 1
chr16_+_32995882 3.67 ENSDART00000170157
protease, serine, 35
chr17_-_30975707 3.64 ENSDART00000138346
Enah/Vasp-like a
chr14_+_49135264 3.64 ENSDART00000084119
si:ch1073-44g3.1
chr1_-_22512063 3.63 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr25_+_20089986 3.62 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr19_-_10243148 3.55 ENSDART00000148073
shisa family member 7
chr3_+_24134418 3.54 ENSDART00000156204
si:ch211-246i5.5
chr24_+_26134029 3.42 ENSDART00000185134
teleost multiple tissue opsin b
chr24_+_39105051 3.37 ENSDART00000115297
MSS51 mitochondrial translational activator
chr1_+_46194333 3.28 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr17_+_52822422 3.19 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr8_+_11687254 3.16 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr24_+_5840258 3.11 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr4_+_5741733 3.07 ENSDART00000110243
POU class 3 homeobox 2a
chr3_+_16265924 2.97 ENSDART00000122519
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr11_+_25257022 2.96 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr25_+_37126921 2.96 ENSDART00000124331
si:ch1073-174d20.1
chr20_+_30490682 2.92 ENSDART00000184871
myelin transcription factor 1-like, a
chr10_+_18877362 2.91 ENSDART00000138334
protein phosphatase 2, regulatory subunit B, alpha b
chr22_-_16377960 2.83 ENSDART00000168170
tetratricopeptide repeat domain 39C
chr8_+_39619087 2.83 ENSDART00000134822
musashi RNA-binding protein 1
chr8_-_52413032 2.82 ENSDART00000183039

chr23_+_28648864 2.81 ENSDART00000189096
L1 cell adhesion molecule, paralog a
chr6_-_6448519 2.81 ENSDART00000180157
ENSDART00000191112
si:ch211-194e18.2
chr21_-_20328375 2.77 ENSDART00000079593
solute carrier family 26 (anion exchanger), member 1
chr11_-_12998400 2.77 ENSDART00000018614
cholinergic receptor, nicotinic, alpha 4b
chr19_-_28789404 2.75 ENSDART00000191453
ENSDART00000026992
SRY (sex determining region Y)-box 4a
chr7_+_30875273 2.75 ENSDART00000173693
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr14_+_15597049 2.74 ENSDART00000159732
si:dkey-203a12.8
chr14_+_15495088 2.71 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
chr2_+_31948352 2.70 ENSDART00000192611
ANKH inorganic pyrophosphate transport regulator b
chr6_-_26559921 2.67 ENSDART00000104532
SRY (sex determining region Y)-box 14
chr11_+_30244356 2.64 ENSDART00000036050
ENSDART00000150080
retinoschisin 1a
chr14_-_33613794 2.63 ENSDART00000010022
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr5_+_31946973 2.61 ENSDART00000189876
ENSDART00000163366
uracil DNA glycosylase b
chr12_-_46959990 2.58 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr22_-_34551568 2.57 ENSDART00000148147
ring finger protein 123
chr10_-_34889053 2.55 ENSDART00000136966
coiled-coil domain containing 169
chr24_+_5237753 2.55 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr6_-_37468971 2.51 ENSDART00000126379
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr23_-_30431333 2.51 ENSDART00000146633
calmodulin binding transcription activator 1a
chr18_-_15373620 2.46 ENSDART00000031752
regulatory factor X, 4
chr5_-_37881345 2.43 ENSDART00000084819
Rho GTPase activating protein 35b
chr10_-_34772211 2.37 ENSDART00000145450
ENSDART00000134307
doublecortin-like kinase 1a
chr25_+_16080181 2.34 ENSDART00000061753
fatty acyl CoA reductase 1
chr5_-_42272517 2.27 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr16_-_35329803 2.26 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
protein tyrosine phosphatase, receptor type, U, b
chr12_+_27117609 2.22 ENSDART00000076154
homeobox B8b
chr23_+_13124085 2.21 ENSDART00000139475
sterile alpha motif domain containing 10b
chr21_+_19070921 2.20 ENSDART00000029874
NK6 homeobox 1
chr6_-_41138854 2.17 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr9_-_16853462 2.15 ENSDART00000160273

chr14_+_45306073 2.15 ENSDART00000034606
ENSDART00000173301
sideroflexin 5b
chr6_-_12296170 2.12 ENSDART00000155685
plakophilin 4
chr24_-_29822913 2.11 ENSDART00000160929
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr17_-_19019635 2.07 ENSDART00000126666
fibronectin leucine rich transmembrane protein 2
chr1_+_961607 2.06 ENSDART00000184660
N-6 adenine-specific DNA methyltransferase 1
chr17_-_18888959 2.05 ENSDART00000080029
adenylate kinase 7b
chr5_+_20147830 2.03 ENSDART00000098727
SV2 related protein a
chr20_-_47731768 1.99 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr11_-_36009924 1.96 ENSDART00000189959
ENSDART00000167472
ENSDART00000191211
ENSDART00000191662
ENSDART00000191780
ENSDART00000192622
ENSDART00000179911
inositol 1,4,5-trisphosphate receptor, type 1b
chr6_+_40629066 1.96 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr18_-_25905574 1.91 ENSDART00000143899
ENSDART00000163369
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr2_-_24962820 1.89 ENSDART00000182767
helicase-like transcription factor
chr11_+_2198831 1.89 ENSDART00000160515
homeobox C6b
chr15_-_13254480 1.88 ENSDART00000190499
zgc:172282
chr23_-_33038423 1.88 ENSDART00000180539
plexin A2
chr10_-_29903165 1.84 ENSDART00000078800
lens intrinsic membrane protein 2.1
chr1_+_45217425 1.80 ENSDART00000179983
ENSDART00000074683
si:ch211-239f4.1
chr1_-_19215336 1.77 ENSDART00000162949
ENSDART00000170680
protein tyrosine phosphatase, receptor type, D, b
chr9_-_42696408 1.75 ENSDART00000144744
collagen, type V, alpha 2a
chr22_+_31821815 1.74 ENSDART00000159825
dedicator of cytokinesis 3
chr20_+_41906960 1.72 ENSDART00000193460
centrosomal protein 85, like
chr18_+_16330025 1.72 ENSDART00000142353
neurotensin
chr23_+_11669109 1.71 ENSDART00000091416
contactin 3a, tandem duplicate 1
chr23_-_7799184 1.67 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr2_+_45068366 1.65 ENSDART00000142175
si:dkey-76d14.2
chr23_+_11669337 1.62 ENSDART00000131355
contactin 3a, tandem duplicate 1
chr19_+_21362553 1.60 ENSDART00000122002
teashirt zinc finger homeobox 1
chr23_-_18030399 1.58 ENSDART00000136967
peptidase M20 domain containing 1, tandem duplicate 1
chr7_+_61480296 1.57 ENSDART00000083255
ADAM metallopeptidase domain 19a
chr25_-_6389713 1.55 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr20_+_20726231 1.53 ENSDART00000147112
zgc:193541
chr19_+_42469058 1.53 ENSDART00000076915
si:dkey-166k12.1
chr14_+_23184517 1.52 ENSDART00000181410
ecto-NOX disulfide-thiol exchanger 2
chr6_+_23931236 1.45 ENSDART00000166079
growth arrest and DNA-damage-inducible, alpha, b
chr12_+_19356623 1.44 ENSDART00000078284
DNA meiotic recombinase 1
chr6_-_46768040 1.43 ENSDART00000154071
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 2
chr24_+_9412450 1.42 ENSDART00000132724
si:ch211-285f17.1
chr9_+_917060 1.40 ENSDART00000082390
transmembrane protein 37
chr14_+_4276394 1.38 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr22_+_5176255 1.37 ENSDART00000092647
ceramide synthase 1
chr2_-_32738535 1.36 ENSDART00000135293
nuclear receptor binding protein 2a
chr7_-_30367650 1.34 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr12_-_1406480 1.33 ENSDART00000152308
si:ch73-105m5.1
chr4_+_20954929 1.33 ENSDART00000143674
neuron navigator 3
chr12_+_27022517 1.33 ENSDART00000152975
male-specific lethal 1 homolog b (Drosophila)
chr5_+_33519943 1.32 ENSDART00000131316
membrane-spanning 4-domains, subfamily A, member 17C.1
chr4_-_16836006 1.31 ENSDART00000010777
lactate dehydrogenase Ba
chr17_+_52823015 1.30 ENSDART00000160507
ENSDART00000186979
Meis homeobox 2a
chr18_-_42333428 1.30 ENSDART00000034225
contactin 5
chr11_+_41243325 1.25 ENSDART00000170657
paired box 7a
chr7_-_26457208 1.21 ENSDART00000173519
zgc:172079
chr23_+_10146542 1.20 ENSDART00000048073
zgc:171775
chr3_+_52545014 1.20 ENSDART00000018908
solute carrier family 27 (fatty acid transporter), member 1a
chr11_+_25044082 1.17 ENSDART00000123263
PHD finger protein 20, a
chr22_-_4644484 1.14 ENSDART00000167748
fibrillin 2b
chr9_-_48370645 1.14 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr19_+_5418006 1.12 ENSDART00000132874
eukaryotic translation initiation factor 1B
chr20_-_45060241 1.09 ENSDART00000185227
kelch-like family member 29
chr23_+_25354856 1.05 ENSDART00000109023
ENSDART00000147440
formin-like 3
chr4_-_5652030 1.05 ENSDART00000010903
radial spoke head 9 homolog
chr9_-_1949915 1.05 ENSDART00000190712
homeobox D3a
chr6_+_35362225 1.04 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr1_+_5402476 1.02 ENSDART00000040204
tubulin, alpha 8 like 2
chr13_-_8892514 1.02 ENSDART00000144553
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr1_+_45217619 1.00 ENSDART00000125037
si:ch211-239f4.1
chr7_+_29080684 0.98 ENSDART00000173709
ENSDART00000173576
ACD, shelterin complex subunit and telomerase recruitment factor
chr1_+_36437585 0.98 ENSDART00000189182
POU class 4 homeobox 2
chr5_+_37785152 0.98 ENSDART00000053511
ENSDART00000189812
myosin Ic, paralog a
chr6_-_50203682 0.97 ENSDART00000083999
ENSDART00000143050
RALY heterogeneous nuclear ribonucleoprotein
chr23_+_36052944 0.96 ENSDART00000103149
homeobox C13a
chr2_+_19785540 0.93 ENSDART00000149789
polypyrimidine tract binding protein 2b
chr2_+_35733335 0.93 ENSDART00000113489
RAS protein activator like 2
chr20_-_4883673 0.92 ENSDART00000145540
ENSDART00000053877
zinc finger, DHHC-type containing 14
chr8_-_45867358 0.92 ENSDART00000132810
ADAM metallopeptidase domain 9
chr15_-_19772372 0.90 ENSDART00000152729
phosphatidylinositol binding clathrin assembly protein b
chr13_-_50614639 0.87 ENSDART00000170527
ventral expressed homeobox
chr22_-_17052381 0.85 ENSDART00000138382
nuclear factor I/A
chr11_-_21586157 0.82 ENSDART00000190095
SLIT-ROBO Rho GTPase activating protein 2
chr19_+_19747430 0.82 ENSDART00000166129
homeobox A9a
chr16_+_10918252 0.81 ENSDART00000172949
POU class 2 homeobox 2a
chr13_+_29519115 0.81 ENSDART00000086711
carbohydrate (chondroitin 6) sulfotransferase 3a
chr11_+_6116503 0.80 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr17_-_17764801 0.80 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr1_+_27153859 0.79 ENSDART00000180184
basonuclin 2
chr19_+_19652439 0.79 ENSDART00000165934
3-hydroxyisobutyrate dehydrogenase a
chr8_+_22977304 0.76 ENSDART00000136784
sterile alpha motif domain containing 10a
chr8_+_23731483 0.74 ENSDART00000099751
Fanconi anemia, complementation group E
chr5_-_63218919 0.73 ENSDART00000149979
tectorin alpha
chr20_+_27428505 0.72 ENSDART00000002641
kinesin family member 26Aa
chr19_-_1002959 0.71 ENSDART00000168138
euchromatic histone-lysine N-methyltransferase 2
chr10_-_25591194 0.69 ENSDART00000131640
T cell lymphoma invasion and metastasis 1a
chr8_-_11324143 0.65 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr1_+_2321384 0.64 ENSDART00000157662
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_37049347 0.64 ENSDART00000109235
bicaudal D homolog 2 (Drosophila)
chr20_-_27733683 0.63 ENSDART00000103317
ENSDART00000138139
zgc:153157
chr3_+_24190207 0.61 ENSDART00000034762
proline rich 15-like a
chr17_-_26610814 0.61 ENSDART00000133402
ENSDART00000016608
mitochondrial ribosomal protein L57
chr19_+_7810028 0.60 ENSDART00000081592
ENSDART00000140719
aquaporin 10b
chr12_-_11560794 0.59 ENSDART00000149098
ENSDART00000169975
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr3_-_19200571 0.58 ENSDART00000131503
ENSDART00000012335
regulatory factor X, 1a (influences HLA class II expression)
chr3_+_52545400 0.58 ENSDART00000184183
solute carrier family 27 (fatty acid transporter), member 1a
chr16_+_38940758 0.57 ENSDART00000102482
ENSDART00000136215
enhancer of yellow 2 homolog (Drosophila)
chr16_-_21903083 0.57 ENSDART00000165849
SET domain, bifurcated 1b
chr10_-_10864331 0.57 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr2_-_4925025 0.51 ENSDART00000160257
discs, large (Drosophila) homolog 1, like
chr6_-_28222592 0.50 ENSDART00000131126
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr8_+_20825987 0.49 ENSDART00000133309
si:ch211-133l5.4
chr11_+_37049105 0.48 ENSDART00000155408
bicaudal D homolog 2 (Drosophila)
chr8_+_12951155 0.48 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr7_-_26844064 0.47 ENSDART00000162241
si:ch211-107p11.3

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc11a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.2 9.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.1 6.5 GO:0035989 tendon development(GO:0035989)
1.0 8.0 GO:1990845 adaptive thermogenesis(GO:1990845)
0.8 3.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.7 2.8 GO:0019532 oxalate transport(GO:0019532)
0.6 2.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.6 1.9 GO:0003403 optic vesicle formation(GO:0003403)
0.6 6.9 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.6 8.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.5 2.6 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.5 5.1 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.5 1.4 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.4 4.9 GO:0034394 protein localization to cell surface(GO:0034394)
0.4 1.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 3.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 9.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.4 1.1 GO:2000793 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.4 3.0 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.4 1.4 GO:0042148 strand invasion(GO:0042148)
0.4 1.8 GO:0071072 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.4 1.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 1.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.3 5.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.3 16.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 4.4 GO:0071698 olfactory placode development(GO:0071698)
0.3 2.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.3 5.5 GO:0014823 response to activity(GO:0014823)
0.3 1.5 GO:0007624 ultradian rhythm(GO:0007624)
0.3 2.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 7.8 GO:0051289 protein homotetramerization(GO:0051289)
0.2 1.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.2 5.1 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.2 2.8 GO:0035094 response to nicotine(GO:0035094)
0.2 2.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 4.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 5.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2 2.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 0.8 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.2 1.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.8 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.2 8.6 GO:0006096 glycolytic process(GO:0006096)
0.2 2.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 1.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.8 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.7 GO:0035889 otolith tethering(GO:0035889)
0.1 2.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.7 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 2.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 3.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 3.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 2.8 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 1.3 GO:0072576 liver morphogenesis(GO:0072576)
0.1 3.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 2.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 3.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 9.9 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 3.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 5.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.6 GO:0060017 parathyroid gland development(GO:0060017)
0.1 2.1 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.1 2.0 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 2.7 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.1 0.9 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.6 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 3.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 4.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.6 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.1 0.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.2 GO:0019859 thymine catabolic process(GO:0006210) uracil catabolic process(GO:0006212) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 3.4 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 3.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 1.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.8 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 3.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 1.9 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.9 GO:0070142 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 4.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 4.7 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 3.6 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.7 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 9.3 GO:0007420 brain development(GO:0007420)
0.0 0.3 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of mRNA catabolic process(GO:0061013) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.5 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 1.2 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.0 GO:0031101 fin regeneration(GO:0031101)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.9 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.6 9.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 5.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 1.7 GO:0005588 collagen type V trimer(GO:0005588)
0.4 17.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 16.6 GO:0005861 troponin complex(GO:0005861)
0.4 1.1 GO:0001534 radial spoke(GO:0001534)
0.3 8.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.0 GO:0060171 stereocilium membrane(GO:0060171)
0.2 9.7 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.2 11.6 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.2 2.8 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.3 GO:0072487 MSL complex(GO:0072487)
0.1 1.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0070390 transcription export complex 2(GO:0070390)
0.1 10.0 GO:0030027 lamellipodium(GO:0030027)
0.1 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.9 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.2 GO:0044545 NSL complex(GO:0044545)
0.1 3.0 GO:0016605 PML body(GO:0016605)
0.1 3.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.0 GO:0070187 telosome(GO:0070187)
0.1 2.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 3.7 GO:0005581 collagen trimer(GO:0005581)
0.0 2.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.7 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 11.9 GO:0043005 neuron projection(GO:0043005)
0.0 4.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 3.1 GO:0034703 cation channel complex(GO:0034703)
0.0 6.5 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 6.0 GO:0045202 synapse(GO:0045202)
0.0 1.7 GO:0030133 transport vesicle(GO:0030133)
0.0 2.1 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:1903136 cuprous ion binding(GO:1903136)
1.9 5.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.6 6.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
1.4 8.6 GO:0004743 pyruvate kinase activity(GO:0004743)
1.0 13.4 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.8 2.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.8 7.8 GO:0005522 profilin binding(GO:0005522)
0.6 2.6 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.6 8.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 2.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 2.7 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.5 2.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.5 1.4 GO:0000150 recombinase activity(GO:0000150)
0.5 5.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.5 1.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 2.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.4 3.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 2.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.3 6.9 GO:0048185 activin binding(GO:0048185)
0.3 6.2 GO:0033691 sialic acid binding(GO:0033691)
0.3 2.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 10.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 5.1 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.3 6.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.6 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 0.8 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.2 8.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.8 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.2 1.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 3.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 2.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.1 GO:0034452 dynactin binding(GO:0034452)
0.1 3.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 4.7 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 2.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 3.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 3.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 10.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 5.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 2.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0031267 small GTPase binding(GO:0031267)
0.0 6.5 GO:0008083 growth factor activity(GO:0008083)
0.0 4.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 5.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 6.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.4 5.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.4 3.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 6.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 6.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation