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PRJDB7713: Age associated transcriptome analysis in 5 tissues of zebrafish

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Results for hoxc4a

Z-value: 0.41

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Transcription factors associated with hoxc4a

Gene Symbol Gene ID Gene Info
ENSDARG00000070338 homeobox C4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc4adr11_v1_chr23_+_36130883_36130883-0.047.3e-01Click!

Activity profile of hoxc4a motif

Sorted Z-values of hoxc4a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_46158078 5.15 ENSDART00000183933
ENSDART00000164055
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr16_-_42894628 2.60 ENSDART00000045600
hemochromatosis type 2
chr8_-_18537866 2.33 ENSDART00000148802
ENSDART00000148962
ENSDART00000149506
nexilin (F actin binding protein)
chr9_-_22834860 2.01 ENSDART00000146486
nebulin
chr12_-_47648538 1.97 ENSDART00000108477
fumarate hydratase
chr16_+_12836143 1.84 ENSDART00000067741
calcium channel, voltage-dependent, gamma subunit 6b
chr24_-_25691020 1.82 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr5_-_38451082 1.76 ENSDART00000136428
cholinergic receptor, nicotinic, epsilon
chr6_-_51771634 1.31 ENSDART00000073847
bladder cancer associated protein
chr25_-_27621268 1.16 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr7_+_4474880 1.15 ENSDART00000143528
si:dkey-83f18.14
chr14_-_34771371 1.13 ENSDART00000160598
ENSDART00000150413
ENSDART00000168910
actin binding LIM protein family, member 3
chr1_+_6172786 1.11 ENSDART00000126468
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr8_+_30664077 1.11 ENSDART00000138750
adenosine A2a receptor a
chr8_-_53044300 1.11 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr10_-_13343831 1.05 ENSDART00000135941
interleukin 11 receptor, alpha
chr12_-_19119176 1.02 ENSDART00000149180
aconitase 2, mitochondrial
chr3_+_5575313 1.01 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
chr12_+_20641102 0.96 ENSDART00000152964
calcium binding and coiled-coil domain 2
chr25_-_13490744 0.94 ENSDART00000056721
lactate dehydrogenase D
chr9_-_22099536 0.92 ENSDART00000101923

chr22_-_19552796 0.88 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr19_+_10855158 0.87 ENSDART00000172219
ENSDART00000170826
apolipoprotein Ea
chr23_+_4709607 0.86 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr1_+_51039558 0.85 ENSDART00000024743
dpy-30 histone methyltransferase complex regulatory subunit
chr15_-_14552101 0.82 ENSDART00000171169
numb homolog (Drosophila)-like
chr20_-_43663494 0.80 ENSDART00000144564

chr13_-_12602920 0.77 ENSDART00000102311
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr3_+_62000822 0.77 ENSDART00000106680
retinoic acid induced 1
chr3_-_59297532 0.76 ENSDART00000187991

chr18_+_3037998 0.73 ENSDART00000185844
ENSDART00000162657
ribosomal protein S3
chr3_-_50443607 0.72 ENSDART00000074036
recoverin a
chr19_+_5480327 0.70 ENSDART00000148794
junction plakoglobin b
chr10_+_11261576 0.70 ENSDART00000155333
hydroxysteroid dehydrogenase like 2
chr12_+_20641471 0.70 ENSDART00000133654
calcium binding and coiled-coil domain 2
chr9_-_1986014 0.70 ENSDART00000142842
homeobox D12a
chr18_+_7456597 0.65 ENSDART00000142270
telomere repeat binding bouquet formation protein 1
chr4_+_33017081 0.63 ENSDART00000151897
si:dkey-26h11.1
chr20_-_23842631 0.63 ENSDART00000153079
si:dkey-15j16.3
chr14_-_858985 0.63 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr1_-_513762 0.63 ENSDART00000148162
ENSDART00000144606
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr9_-_12811936 0.62 ENSDART00000188490
myosin X-like 3
chr3_-_3798755 0.61 ENSDART00000170535
guanylate cyclase 2C
chr23_-_21453614 0.61 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr2_-_7845110 0.61 ENSDART00000091987
si:ch211-38m6.7
chr2_+_37140448 0.61 ENSDART00000045016
ENSDART00000142940
peroxisomal biogenesis factor 19
chr22_+_1615691 0.60 ENSDART00000171555
si:ch211-255f4.13
chr4_-_13548806 0.59 ENSDART00000067155
interleukin 22
chr17_+_31914877 0.59 ENSDART00000177801
family with sequence similarity 196 member A
chr17_-_10122204 0.58 ENSDART00000160751

chr2_+_42318012 0.58 ENSDART00000138137
finTRIM family, member 8
chr2_-_16216568 0.58 ENSDART00000173758
Rho guanine nucleotide exchange factor (GEF) 4
chr11_-_2838699 0.57 ENSDART00000066189
LHFPL tetraspan subfamily member 5a
chr2_-_30668580 0.57 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr9_+_11281969 0.56 ENSDART00000110691
wingless-type MMTV integration site family, member 6b
chr3_-_13921173 0.56 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr19_+_25154066 0.55 ENSDART00000163220
si:ch211-239d6.2
chr25_+_13321307 0.55 ENSDART00000161284
si:ch211-194m7.5
chr23_-_1660708 0.55 ENSDART00000175138

chr5_+_71802014 0.54 ENSDART00000124939
ENSDART00000097164
LIM homeobox 3
chr18_+_7456888 0.52 ENSDART00000081468
telomere repeat binding bouquet formation protein 1
chr10_+_42423318 0.52 ENSDART00000134282
neuropeptide Y receptor Y8a
chr18_+_48168755 0.52 ENSDART00000128189
somatolactin alpha
chr6_-_33878665 0.51 ENSDART00000129916
transmembrane protein 69
chr14_-_4556896 0.50 ENSDART00000044678
ENSDART00000192863
gamma-aminobutyric acid type A receptor alpha2 subunit
chr17_+_2162916 0.50 ENSDART00000103775
p21 protein (Cdc42/Rac)-activated kinase 6a
chr13_-_9450210 0.49 ENSDART00000133768
Pim proto-oncogene, serine/threonine kinase, related 152
chr4_-_2219705 0.49 ENSDART00000131046
si:ch73-278m9.1
chr12_-_26153101 0.49 ENSDART00000076051
opsin 4b
chr3_-_34136778 0.48 ENSDART00000131951
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr9_+_30211038 0.48 ENSDART00000190847
SUMO1/sentrin specific peptidase 7a
chr22_+_1556948 0.48 ENSDART00000159050
si:ch211-255f4.8
chr25_-_13320986 0.48 ENSDART00000169238
si:ch211-194m7.8
chr7_+_38811800 0.47 ENSDART00000052322
zgc:110699
chr1_+_21731382 0.47 ENSDART00000054395
paired box 5
chr11_+_7214353 0.46 ENSDART00000156764
NACHT and WD repeat domain containing 1
chr22_+_23359369 0.45 ENSDART00000170886
DENN/MADD domain containing 1B
chr22_+_1568306 0.45 ENSDART00000163223
si:ch211-255f4.9
chr20_+_40457599 0.45 ENSDART00000017553
serine incorporator 1
chr5_+_33498253 0.44 ENSDART00000140993
membrane-spanning 4-domains, subfamily A, member 17c.2
chr4_+_36150332 0.44 ENSDART00000161697
zinc finger protein 1116
chr5_+_34623107 0.43 ENSDART00000184126
ectodermal-neural cortex 1
chr20_-_9095105 0.42 ENSDART00000140792
OMA1 zinc metallopeptidase
chr5_-_28109416 0.42 ENSDART00000042002
si:ch211-48m9.1
chr5_-_16218777 0.41 ENSDART00000141698
kringle containing transmembrane protein 1
chr2_+_38373272 0.41 ENSDART00000113111
proteasome subunit beta 5
chr1_+_51721851 0.41 ENSDART00000040397
peroxiredoxin 2
chr9_+_1139378 0.40 ENSDART00000170033
solute carrier family 15 (oligopeptide transporter), member 1a
chr9_+_48761455 0.40 ENSDART00000139631
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr6_+_11249706 0.40 ENSDART00000186547
ENSDART00000193287
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr17_-_20558961 0.40 ENSDART00000155993
SH3 and PX domains 2Ab
chr20_-_31308805 0.40 ENSDART00000147045
hippocalcin-like 1
chr21_+_8276989 0.39 ENSDART00000028265
nuclear receptor subfamily 5, group A, member 1b
chr8_+_29742237 0.39 ENSDART00000133955
ENSDART00000020621
mitogen-activated protein kinase 4
chr15_+_31899312 0.39 ENSDART00000155315
furry homolog a (Drosophila)
chr1_-_31534089 0.38 ENSDART00000007770
ladybird homeobox 1b
chr7_-_57509447 0.38 ENSDART00000051973
ENSDART00000147036
sirtuin 3
chr1_+_418869 0.38 ENSDART00000152173
tripeptidyl peptidase 2
chr10_-_31015535 0.37 ENSDART00000146116
pannexin 3
chr3_+_23029484 0.37 ENSDART00000187900
N-acetylglutamate synthase
chr23_-_16485190 0.37 ENSDART00000155038
si:dkeyp-100a5.4
chr19_+_31873308 0.37 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr22_+_737211 0.36 ENSDART00000017305
zinc finger protein 76
chr19_+_3213914 0.35 ENSDART00000193144
zgc:86598
chr2_+_3201345 0.34 ENSDART00000130349
wingless-type MMTV integration site family, member 9A
chr23_-_19225709 0.34 ENSDART00000080099
O-acyl-ADP-ribose deacylase 1
chr14_-_451555 0.34 ENSDART00000190906
FAT atypical cadherin 4
chr1_+_9086942 0.34 ENSDART00000055023
calcium channel, voltage-dependent, gamma subunit 3a
chr24_-_38657683 0.33 ENSDART00000154843
si:ch1073-164k15.3
chr2_+_47708853 0.33 ENSDART00000124307
muscleblind-like splicing regulator 1
chr7_+_21272833 0.33 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr11_-_45141309 0.32 ENSDART00000181736
calcium activated nucleotidase 1b
chr15_-_17619306 0.31 ENSDART00000184011
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr6_+_612594 0.31 ENSDART00000150903
kynureninase
chr13_+_29462249 0.30 ENSDART00000147903
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1a
chr15_+_22867174 0.30 ENSDART00000035812
glutamate receptor, ionotropic, kainate 4
chr9_+_23895711 0.30 ENSDART00000034686
COP9 signalosome subunit 8
chr4_+_77943184 0.30 ENSDART00000159094
protein kinase C and casein kinase substrate in neurons 2
chr1_+_49668423 0.30 ENSDART00000150880
testis specific, 10
chr4_+_45148652 0.29 ENSDART00000150798
si:dkey-51d8.9
chr3_+_40164129 0.29 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr6_+_15373153 0.29 ENSDART00000155865
teleost multiple tissue opsin 2a
chr10_-_14556978 0.29 ENSDART00000126643
zgc:153395
chr1_+_11882186 0.29 ENSDART00000193419
sorting nexin 8b
chr20_+_32552912 0.28 ENSDART00000009691
Scm polycomb group protein like 4
chr17_+_50524573 0.28 ENSDART00000187974

chr12_-_6880694 0.28 ENSDART00000171846
protocadherin-related 15b
chr1_-_19502322 0.28 ENSDART00000181888
ENSDART00000044030
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr13_+_12299997 0.27 ENSDART00000108535
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr2_-_22631498 0.27 ENSDART00000146425
serine/threonine kinase 25b
chr4_+_69191065 0.26 ENSDART00000170595
zinc finger protein 1075
chr14_-_32486757 0.26 ENSDART00000148830
MCF.2 cell line derived transforming sequence a
chr7_-_52388734 0.24 ENSDART00000174186
WD repeat domain 93
chr23_+_16638639 0.24 ENSDART00000143545
syntaphilin b
chr22_+_5532003 0.24 ENSDART00000106174
si:ch73-256j6.2
chr1_+_57787642 0.24 ENSDART00000127091
si:dkey-1c7.2
chr6_+_11250033 0.24 ENSDART00000065411
ENSDART00000132677
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr11_+_45436703 0.24 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr3_-_48716422 0.23 ENSDART00000164979
si:ch211-114m9.1
chr9_-_14504834 0.23 ENSDART00000056103
neuropilin 2b
chr2_+_2223837 0.22 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr8_+_7801060 0.22 ENSDART00000161618
transcription factor binding to IGHM enhancer 3a
chr18_+_17827149 0.22 ENSDART00000190237
ENSDART00000189345
si:ch211-216l23.1
chr21_+_25802190 0.22 ENSDART00000128987
neurofibromin 2b (merlin)
chr14_-_413273 0.22 ENSDART00000163976
ENSDART00000179907
FAT atypical cadherin 4
chr5_-_21422390 0.21 ENSDART00000144198
teneurin transmembrane protein 1
chr17_-_15229787 0.20 ENSDART00000039165
serine/threonine/tyrosine interacting protein
chr2_+_20605925 0.20 ENSDART00000191510
olfactomedin-like 2Bb
chr19_+_19032141 0.19 ENSDART00000192432
copine IVb
chr24_+_21540842 0.19 ENSDART00000091529
WAS protein family, member 3b
chr12_+_46742805 0.19 ENSDART00000192236
plasminogen activator, urokinase b
chr8_-_12867128 0.18 ENSDART00000142201
solute carrier family 2 (facilitated glucose transporter), member 6
chr2_+_105748 0.18 ENSDART00000169601

chr3_+_3681116 0.18 ENSDART00000109618
ADP-ribosyltransferase 4 (Dombrock blood group)
chr6_+_11250316 0.18 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr12_-_31794908 0.17 ENSDART00000105583
ENSDART00000153449
N-acetyltransferase 9 (GCN5-related, putative)
chr23_-_1348933 0.17 ENSDART00000168981

chr14_+_32430982 0.17 ENSDART00000017179
ENSDART00000123382
ENSDART00000075593
coagulation factor IXa
chr3_+_26288981 0.16 ENSDART00000163500
ras homolog family member T1a
chr8_-_12867434 0.16 ENSDART00000081657
solute carrier family 2 (facilitated glucose transporter), member 6
chr13_-_35808904 0.16 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr15_+_5360407 0.15 ENSDART00000110420
odorant receptor, family A, subfamily 112, member 1
chr16_-_12173399 0.14 ENSDART00000142574
calsyntenin 3
chr11_+_34760628 0.14 ENSDART00000087216
si:dkey-202e22.2
chr22_-_12160283 0.14 ENSDART00000146785
ENSDART00000128176
transmembrane protein 163b
chr14_-_26425416 0.14 ENSDART00000088690
lectin, mannose-binding 2
chr1_+_513986 0.14 ENSDART00000109083
ENSDART00000081945
thioredoxin-like 4B
chr24_+_24461341 0.14 ENSDART00000147658
basic helix-loop-helix family, member e22
chr23_+_28809002 0.14 ENSDART00000134121
ENSDART00000183661
peroxisomal biogenesis factor 14
chr21_-_22635245 0.13 ENSDART00000115224
ENSDART00000101782
nectin cell adhesion molecule 1a
chr12_+_17620067 0.13 ENSDART00000073599
radial spoke head 10 homolog B
chr7_-_66868543 0.12 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr24_+_24461558 0.12 ENSDART00000182424
basic helix-loop-helix family, member e22
chr6_+_35052721 0.12 ENSDART00000191090
ENSDART00000082940
U2AF homology motif (UHM) kinase 1
chr14_+_22591624 0.10 ENSDART00000108987
GDNF family receptor alpha 4b
chr24_+_744713 0.10 ENSDART00000067764
serine/threonine kinase 17a
chr12_+_31735159 0.09 ENSDART00000185442
si:dkey-49c17.3
chr2_+_50608099 0.09 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr9_-_27398369 0.08 ENSDART00000186499
testis expressed 30
chr12_-_35830625 0.08 ENSDART00000180028

chr23_-_17657348 0.07 ENSDART00000054736
basic helix-loop-helix family, member e23
chr18_+_14619544 0.07 ENSDART00000010821
UTP4, small subunit processome component
chr18_-_5527050 0.06 ENSDART00000145400
ENSDART00000132498
ENSDART00000146209
zgc:153317
chr24_+_7800486 0.05 ENSDART00000145504
protein tyrosine phosphatase, receptor type, h
chr17_+_51682429 0.05 ENSDART00000004379
nucleolar protein 10
chr3_+_36284986 0.05 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr7_+_24573721 0.04 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
chr2_-_17044959 0.04 ENSDART00000090260
chloride channel, voltage-sensitive 2a
chr12_+_7497882 0.04 ENSDART00000134608
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr22_+_34784075 0.03 ENSDART00000167538
ligand dependent nuclear receptor corepressor
chr11_+_30817943 0.03 ENSDART00000150130
ENSDART00000159997
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr10_+_26747755 0.02 ENSDART00000100329
coagulation factor IXb
chr19_+_43359075 0.02 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
Yes-related kinase
chr6_+_24420523 0.02 ENSDART00000185461
transforming growth factor, beta receptor III
chr21_-_13123176 0.00 ENSDART00000144866
ENSDART00000024616
family with sequence similarity 219, member Aa

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc4a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.3 2.0 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.3 2.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 0.9 GO:0006089 lactate metabolic process(GO:0006089)
0.3 1.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 0.9 GO:0097242 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.2 2.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 5.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.2 0.6 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 2.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0097052 ketone catabolic process(GO:0042182) L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.4 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.8 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.7 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.6 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.4 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.5 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:0043393 regulation of protein binding(GO:0043393)
0.0 0.3 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.6 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.8 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.2 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.1 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.8 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.6 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 2.0 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.2 GO:0070187 telosome(GO:0070187)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 4.3 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.0 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 0.5 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.6 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 3.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.9 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.4 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.3 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.4 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 2.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 1.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0019838 growth factor binding(GO:0019838)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID BMP PATHWAY BMP receptor signaling
0.0 2.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 3.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 5.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)